Lista de obras - Wolfgang Wiechert - Dominio Público Uruguay

(13)C Tracers for Glucose Degrading Pathway Discrimination in Gluconobacter oxydans 621H.

artículo científico publicado en 2015

13C labeling experiments at metabolic nonstationary conditions: an exploratory study.

artículo científico publicado en 2008

13C-flux spectral analysis of host-pathogen metabolism reveals a mixed diet for intracellular Mycobacterium tuberculosis

artículo científico publicado en 2013

13CFLUX2--high-performance software suite for (13)C-metabolic flux analysis.

artículo científico publicado en 2012

40 Years of Biotechnology Research at Forschungszentrum Jülich

artículo científico publicado en 2017

A FRET-based biosensor for the quantification of glucose in culture supernatants of mL scale microbial cultivations

scientific article published on 21 August 2019

A Pareto approach to resolve the conflict between information gain and experimental costs: Multiple-criteria design of carbon labeling experiments

artículo científico publicado en 2018

A Primer to13C Metabolic Flux Analysis

A Toolbox of Genetically Encoded FRET-Based Biosensors for Rapid l-Lysine Analysis

artículo científico publicado en 2016

A closer look at Aspergillus: online monitoring via scattered light enables reproducible phenotyping

scientific article published on 05 August 2019

A disposable picolitre bioreactor for cultivation and investigation of industrially relevant bacteria on the single cell level.

artículo científico publicado en 2012

A framework for accelerated phototrophic bioprocess development: integration of parallelized microscale cultivation, laboratory automation and Kriging-assisted experimental design.

artículo científico publicado en 2017

A scientific workflow framework for (13)C metabolic flux analysis.

artículo científico publicado en 2015

Absolute quantification of Corynebacterium glutamicum glycolytic and anaplerotic enzymes by QconCAT.

artículo científico publicado en 2014

An Efficient Route to Both Enantiomers of allo-Threonine by Simultaneous Amino Acid Racemase-Catalyzed Isomerization of Threonine and Crystallization

An Enzymatic 2-Step Cofactor and Co-Product Recycling Cascade towards a Chiral 1,2-Diol. Part I: Cascade Design.

artículo científico publicado en 2019

An Online Provenance Service for Distributed Metabolic Flux Analysis Workflows

An evaluation of genetically encoded FRET-based biosensors for quantitative metabolite analyses in vivo

artículo científico publicado en 2014

An introduction to 13C metabolic flux analysis.

artículo científico publicado en 2002

Analyzing Microbial Population Heterogeneity-Expanding the Toolbox of Microfluidic Single-Cell Cultivations

scientific article published on 26 April 2019

Assessment of robustness against dissolved oxygen/substrate oscillations for C. glutamicum DM1933 in two-compartment bioreactor.

artículo científico publicado en 2013

Atomic Force Microscope Cantilevers Used as Sensors for Monitoring Microdrop Evaporation

Automated growth rate determination in high-throughput microbioreactor systems.

artículo científico publicado en 2017

Automation of a Nile red staining assay enables high throughput quantification of microalgal lipid production

artículo científico publicado en 2016

Bayesian calibration, process modeling and uncertainty quantification in biotechnology

artículo científico publicado en 2022

Beyond growth rate 0.6: Corynebacterium glutamicum cultivated in highly diluted environments

artículo científico publicado en 2012

Beyond growth rate 0.6: What drives Corynebacterium glutamicum to higher growth rates in defined medium.

artículo científico publicado en 2013

Bioprocess automation on a Mini Pilot Plant enables fast quantitative microbial phenotyping.

artículo científico publicado en 2015

Characterization of Sigma Factor Genes in TK24 Using a Genomic Library-Based Approach for Multiple Gene Deletions ⬇️

article

Chassis organism from Corynebacterium glutamicum – Genome reduction as a tool toward improved strains for synthetic biology and industrial biotechnology

scholarly article by Meike Baumgart published in July 2016

Chassis organism from Corynebacterium glutamicum--a top-down approach to identify and delete irrelevant gene clusters

artículo científico publicado en 2014

Cloud MapReduce for Monte Carlo bootstrap applied to Metabolic Flux Analysis

Coarse-graining bacteria colonies for modelling critical solute distributions in picolitre bioreactors for bacterial studies on single-cell level.

artículo científico publicado en 2017

Collisional fragmentation of central carbon metabolites in LC-MS/MS increases precision of ¹³C metabolic flux analysis

artículo científico publicado en 2011

Combinatorial impact of Sec signal peptides from Bacillus subtilis and bioprocess conditions on heterologous cutinase secretion by Corynebacterium glutamicum

artículo científico publicado en 2018

Combined fluxomics and transcriptomics analysis of glucose catabolism via a partially cyclic pentose phosphate pathway in Gluconobacter oxydans 621H.

artículo científico publicado en 2013

Comparative 13C metabolic flux analysis of pyruvate dehydrogenase complex-deficient, L-valine-producing Corynebacterium glutamicum.

artículo científico

Comparative evaluation of phototrophic microtiter plate cultivation against laboratory-scale photobioreactors

artículo científico publicado en 2017

Comprehensive analysis of metabolic sensitivity of 1,4-butanediol producing Escherichia coli toward substrate and oxygen availability

scientific article published on 01 November 2019

Computational tools for isotopically instationary 13C labeling experiments under metabolic steady state conditions.

artículo científico publicado en 2006

Corrigendum: The Design of FluxML: A Universal Modeling Language for 13C Metabolic Flux Analysis

scientific article published on 30 July 2019

Corynebacterium glutamicum Chassis C1*: Building and Testing a Novel Platform Host for Synthetic Biology and Industrial Biotechnology.

artículo científico

Customizable Visualization of Multi-omics Data in the Context of Biochemical Networks

scholarly article published July 2009

Customizable Visualization on Demand for Hierarchically Organized Information in Biochemical Networks

scholarly article by Peter Droste et al published 2010 in Lecture Notes in Computer Science

Cutting the Gordian Knot: Identifiability of anaplerotic reactions in Corynebacterium glutamicum by means of (13) C-metabolic flux analysis

artículo científico publicado en 2015

Design and validation of a parallelized micro-photobioreactor enabling phototrophic bioprocess development at elevated throughput.

artículo científico publicado en 2016

Determination of flux directions by thermodynamic network analysis: Computing informative metabolite pools

Developing a new production host from a blueprint: Bacillus pumilus as an industrial enzyme producer

scientific article published on 24 March 2014

Differential transcriptomic analysis reveals hidden light response in Streptomyces lividans

artículo científico publicado en 2017

Discrete-continuous reaction-diffusion model with mobile point-like sources and sinks.

artículo científico publicado en 2016

Dynamic flux balance analysis with nonlinear objective function.

artículo científico publicado en 2017

Editorial: Synthetic biology--ready for application.

artículo científico publicado en 2015

Effective Production of (S)-α-Hydroxy ketones: An Reaction Engineering Approach

article

Emerging Corynebacterium glutamicum systems biology

artículo científico publicado en 2006

Engineering of Corynebacterium glutamicum for minimized carbon loss during utilization of D-xylose containing substrates

artículo científico publicado en 2014

Error propagation analysis for quantitative intracellular metabolomics

artículo científico publicado en 2012

Experimental design principles for isotopically instationary 13C labeling experiments

artículo científico publicado en 2006

Extensive exometabolome analysis reveals extended overflow metabolism in various microorganisms

artículo científico publicado en 2012

Fast and reliable strain characterization of Streptomyces lividans through micro-scale cultivation.

artículo científico publicado en 2017

FeedER: a feedback-regulated enzyme-based slow-release system for fed-batch cultivation in microtiter plates

artículo científico publicado en 2019

First- and second-order parameter sensitivities of a metabolically and isotopically non-stationary biochemical network model

scholarly article published 19 November 2012

Fluxomics: mass spectrometry versus quantitative imaging

artículo científico publicado en 2007

From stationary to instationary metabolic flux analysis

artículo científico publicado en 2005

Generic Protocol for Optimization of Heterologous Protein Production Using Automated Microbioreactor Technology

artículo científico publicado en 2017

Germination and Growth Analysis of at the Single-Cell Level Under Varying Medium Compositions

article

Homogenizing bacterial cell factories: Analysis and engineering of phenotypic heterogeneity.

artículo científico publicado en 2017

How to measure metabolic fluxes: a taxonomic guide for (13)C fluxomics

artículo científico publicado en 2014

Hydroxynitrile Lyase from Arabidopsis thaliana: Identification of Reaction Parameters for Enantiopure Cyanohydrin Synthesis by Pure and Immobilized Catalyst

Image-Based Single Cell Profiling: High-Throughput Processing of Mother Machine Experiments.

artículo científico publicado en 2016

Improved microscale cultivation of Pichia pastoris for clonal screening.

artículo científico publicado en 2018

Influence of Organic Solvents on Enzymatic Asymmetric Carboligations

artículo científico publicado en 2012

Interpretation of metabolic flux maps by limitation potentials and constrained limitation sensitivities

artículo científico publicado en 2006

Investigating the dynamic behavior of biochemical networks using model families

artículo científico

Isotopically non-stationary metabolic flux analysis: complex yet highly informative

artículo científico publicado en 2013

Kriging with trend functions nonlinear in their parameters: Theory and application in enzyme kinetics

artículo científico publicado en 2017

Laboratory-scale photobiotechnology-current trends and future perspectives.

artículo científico publicado en 2017

Less sacrifice, more insight: Repeated low-volume sampling of microbioreactor cultivations enables accelerated deep phenotyping of microbial strain libraries

scientific article published on 19 November 2018

Light-responsive control of bacterial gene expression: precise triggering of the lac promoter activity using photocaged IPTG.

artículo científico publicado en 2014

Live cell imaging of SOS and prophage dynamics in isogenic bacterial populations

artículo científico publicado en 2015

MMT--a pathway modeling tool for data from rapid sampling experiments

artículo científico publicado en 2002

Mechanistic pathway modeling for industrial biotechnology: challenging but worthwhile

artículo científico publicado en 2011

Metabolic Flux Analysis in the Cloud

Metabolic Footprinting of Microbial Systems Based on Comprehensive In Silico Predictions of MS/MS Relevant Data

scientific article published on 17 March 2022

Metabolic flux analysis at ultra short time scale: isotopically non-stationary 13C labeling experiments

artículo científico publicado en 2006

Metabolic isotopomer labeling systems. Part II: structural flux identifiability analysis

artículo científico publicado en 2003

Metabolic isotopomer labeling systems. Part III: path tracing

artículo científico publicado en 2013

Metabolic profile of 1,5-diaminopentane producing Corynebacterium glutamicum under scale-down conditions: Blueprint for robustness to bioreactor inhomogeneities.

artículo científico publicado en 2016

Microbial single-cell analysis in picoliter-sized batch cultivation chambers

artículo científico publicado en 2018

Microbioreactor systems for accelerated bioprocess development

artículo científico publicado en 2017

Microfluidic growth chambers with optical tweezers for full spatial single-cell control and analysis of evolving microbes

artículo científico publicado en 2013

Microfluidic picoliter bioreactor for microbial single-cell analysis: fabrication, system setup, and operation

artículo científico publicado en 2013

Miniaturized and automated adaptive laboratory evolution: Evolving Corynebacterium glutamicum towards an improved d-xylose utilization

artículo científico

Modeling and CFD simulation of nutrient distribution in picoliter bioreactors for bacterial growth studies on single-cell level

artículo científico publicado en 2015

Modeling and simulation: tools for metabolic engineering

artículo científico publicado en 2002

Modeling languages for biochemical network simulation: reaction vs equation based approaches

artículo científico publicado en 2010

Multi-Omics and Targeted Approaches to Determine the Role of Cellular Proteases in Streptomyces Protein Secretion.

artículo científico publicado en 2018

Multiscale dynamic modeling and simulation of a biorefinery

scientific article published on 21 July 2019

New tools for mass isotopomer data evaluation in (13)C flux analysis: mass isotope correction, data consistency checking, and precursor relationships.

artículo científico publicado en 2004

Non-Invasive Microbial Metabolic Activity Sensing at Single Cell Level by Perfusion of Calcein Acetoxymethyl Ester

artículo científico publicado en 2015

Nondestructive and noncontact method for determining the spring constant of rectangular cantilevers

artículo científico publicado en 2007

Omix - A Visualization Tool for Metabolic Networks with Highest Usability and Customizability in Focus

scholarly article by Peter Droste et al published 25 April 2013 in Chemie Ingenieur Technik

Optical sensors for monitoring dynamic changes of intracellular metabolite levels in mammalian cells

artículo científico publicado en 2011

Parallelized microscale fed-batch cultivation in online-monitored microtiter plates: implications of media composition and feed strategies for process design and performance

artículo científico publicado en 2019

Photocaged Arabinose: A Novel Optogenetic Switch for Rapid and Gradual Control of Microbial Gene Expression

artículo científico publicado en 2015

Process inhomogeneity leads to rapid side product turnover in cultivation of Corynebacterium glutamicum

artículo científico publicado en 2014

Quantitative measurements in single-cell analysis: towards scalability in microbial bioprocess development

artículo científico publicado en 2018

Quantitative metabolomics: a phantom?

artículo científico publicado en 2014

Rapid and comprehensive evaluation of microalgal fatty acids via untargeted gas chromatography and time-of-flight mass spectrometry

artículo científico publicado en 2019

Rapid assessment of oxygen transfer impact for Corynebacterium glutamicum

artículo científico publicado en 2014

Rapid inoculation of single bacteria into parallel picoliter fermentation chambers

Real-time monitoring of fungal growth and morphogenesis at single-cell resolution

artículo científico publicado en 2016

Revisiting the Growth Modulon of Corynebacterium glutamicum Under Glucose Limited Chemostat Conditions

scientific article published on 15 October 2020

Screening of a genome-reduced Corynebacterium glutamicum strain library for improved heterologous cutinase secretion

artículo científico publicado en 2020

Semi-automatic drawing of metabolic networks

Serial 13C-based flux analysis of an L-phenylalanine-producing E. coli strain using the sensor reactor.

artículo científico publicado en 2004

Sessile-drop-induced bending of atomic force microscope cantilevers: a model system for monitoring microdrop evaporation

Simultaneous utilization of glucose and gluconate in Penicillium chrysogenum during overflow metabolism

artículo científico publicado en 2013

Single-cell microfluidics: opportunity for bioprocess development

artículo científico publicado en 2014

Spatiotemporal microbial single-cell analysis using a high-throughput microfluidics cultivation platform

artículo científico publicado en 2015

Stationary versus non-stationary 13C-MFA: A comparison using a consistent dataset

artículo científico publicado en 2010

Tailor-made catalytically active inclusion bodies for different applications in biocatalysis

Tailoring a Stabilized Variant of Hydroxynitrile Lyase from Arabidopsis thaliana

artículo científico publicado en 2012

Technical bias of microcultivation environments on single-cell physiology

artículo científico publicado en 2015

The Design of FluxML: A Universal Modeling Language for 13C Metabolic Flux Analysis

scientific article published on 24 May 2019

The benefits of being transient: isotope-based metabolic flux analysis at the short time scale ⬇️

artículo científico publicado el 6 de julio de 2011

The effect of composition on diffusion of macromolecules in a crowded environment.

artículo científico publicado en 2015

The linkage between nutrient supply, intracellular enzyme abundances and bacterial growth: New evidences from the central carbon metabolism of Corynebacterium glutamicum

artículo científico publicado en 2017

The thermodynamic meaning of metabolic exchange fluxes

artículo científico publicado en 2007

The topology of metabolic isotope labeling networks

artículo científico publicado en 2007

Time-resolved, single-cell analysis of induced and programmed cell death via non-invasive propidium iodide and counterstain perfusion

artículo científico publicado en 2016

To be certain about the uncertainty: Bayesian statistics for 13 C metabolic flux analysis.

artículo científico

Translating biochemical network models between different kinetic formats

artículo científico publicado en 2008

Use of a Sec signal peptide library from Bacillus subtilis for the optimization of cutinase secretion in Corynebacterium glutamicum

artículo científico publicado en 2016

Visual workflows for 13C-metabolic flux analysis

artículo científico publicado en 2014

Visualizing multi-omics data in metabolic networks with the software Omix: a case study

artículo científico publicado en 2011

Visualizing regulatory interactions in metabolic networks

artículo científico publicado en 2007

Vizardous: interactive analysis of microbial populations with single cell resolution.

artículo científico publicado en 2015

Workflows for Metabolic Flux Analysis: Data Integration and Human Interaction

bletl - A Python package for integrating BioLector microcultivation devices in the Design-Build-Test-Learn cycle

artículo científico publicado en 2022

mycelyso - high-throughput analysis of Streptomyces mycelium live cell imaging data

scientific article published on 04 September 2019

pH fluctuations imperil the robustness of C. glutamicum to short term oxygen limitation

artículo científico publicado en 2017

μMORE: A microfluidic magnetic oscillation reactor for accelerated parameter optimization in biocatalysis

artículo científico publicado en 2016

Lista de obras de Wolfgang Wiechert

(13)C Tracers for Glucose Degrading Pathway Discrimination in Gluconobacter oxydans 621H.

13C labeling experiments at metabolic nonstationary conditions: an exploratory study.

13C-flux spectral analysis of host-pathogen metabolism reveals a mixed diet for intracellular Mycobacterium tuberculosis

13CFLUX2--high-performance software suite for (13)C-metabolic flux analysis.

40 Years of Biotechnology Research at Forschungszentrum Jülich

A FRET-based biosensor for the quantification of glucose in culture supernatants of mL scale microbial cultivations

A Pareto approach to resolve the conflict between information gain and experimental costs: Multiple-criteria design of carbon labeling experiments

A Primer to13C Metabolic Flux Analysis

A Toolbox of Genetically Encoded FRET-Based Biosensors for Rapid l-Lysine Analysis

A closer look at Aspergillus: online monitoring via scattered light enables reproducible phenotyping

A disposable picolitre bioreactor for cultivation and investigation of industrially relevant bacteria on the single cell level.

A framework for accelerated phototrophic bioprocess development: integration of parallelized microscale cultivation, laboratory automation and Kriging-assisted experimental design.

A scientific workflow framework for (13)C metabolic flux analysis.

Absolute quantification of Corynebacterium glutamicum glycolytic and anaplerotic enzymes by QconCAT.

An Efficient Route to Both Enantiomers of allo-Threonine by Simultaneous Amino Acid Racemase-Catalyzed Isomerization of Threonine and Crystallization

An Enzymatic 2-Step Cofactor and Co-Product Recycling Cascade towards a Chiral 1,2-Diol. Part I: Cascade Design.

An Online Provenance Service for Distributed Metabolic Flux Analysis Workflows

An evaluation of genetically encoded FRET-based biosensors for quantitative metabolite analyses in vivo

An introduction to 13C metabolic flux analysis.

Analyzing Microbial Population Heterogeneity-Expanding the Toolbox of Microfluidic Single-Cell Cultivations

Assessment of robustness against dissolved oxygen/substrate oscillations for C. glutamicum DM1933 in two-compartment bioreactor.

Atomic Force Microscope Cantilevers Used as Sensors for Monitoring Microdrop Evaporation

Automated growth rate determination in high-throughput microbioreactor systems.

Automation of a Nile red staining assay enables high throughput quantification of microalgal lipid production

Bayesian calibration, process modeling and uncertainty quantification in biotechnology

Beyond growth rate 0.6: Corynebacterium glutamicum cultivated in highly diluted environments

Beyond growth rate 0.6: What drives Corynebacterium glutamicum to higher growth rates in defined medium.

Bioprocess automation on a Mini Pilot Plant enables fast quantitative microbial phenotyping.

Characterization of Sigma Factor Genes in TK24 Using a Genomic Library-Based Approach for Multiple Gene Deletions ⬇️

Chassis organism from Corynebacterium glutamicum – Genome reduction as a tool toward improved strains for synthetic biology and industrial biotechnology

Chassis organism from Corynebacterium glutamicum--a top-down approach to identify and delete irrelevant gene clusters

Cloud MapReduce for Monte Carlo bootstrap applied to Metabolic Flux Analysis

Coarse-graining bacteria colonies for modelling critical solute distributions in picolitre bioreactors for bacterial studies on single-cell level.

Collisional fragmentation of central carbon metabolites in LC-MS/MS increases precision of ¹³C metabolic flux analysis

Combinatorial impact of Sec signal peptides from Bacillus subtilis and bioprocess conditions on heterologous cutinase secretion by Corynebacterium glutamicum

Combined fluxomics and transcriptomics analysis of glucose catabolism via a partially cyclic pentose phosphate pathway in Gluconobacter oxydans 621H.

Comparative 13C metabolic flux analysis of pyruvate dehydrogenase complex-deficient, L-valine-producing Corynebacterium glutamicum.

Comparative evaluation of phototrophic microtiter plate cultivation against laboratory-scale photobioreactors

Comprehensive analysis of metabolic sensitivity of 1,4-butanediol producing Escherichia coli toward substrate and oxygen availability

Computational tools for isotopically instationary 13C labeling experiments under metabolic steady state conditions.

Corrigendum: The Design of FluxML: A Universal Modeling Language for 13C Metabolic Flux Analysis

Corynebacterium glutamicum Chassis C1*: Building and Testing a Novel Platform Host for Synthetic Biology and Industrial Biotechnology.

Customizable Visualization of Multi-omics Data in the Context of Biochemical Networks

Customizable Visualization on Demand for Hierarchically Organized Information in Biochemical Networks

Cutting the Gordian Knot: Identifiability of anaplerotic reactions in Corynebacterium glutamicum by means of (13) C-metabolic flux analysis

Design and validation of a parallelized micro-photobioreactor enabling phototrophic bioprocess development at elevated throughput.

Determination of flux directions by thermodynamic network analysis: Computing informative metabolite pools

Developing a new production host from a blueprint: Bacillus pumilus as an industrial enzyme producer

Differential transcriptomic analysis reveals hidden light response in Streptomyces lividans

Discrete-continuous reaction-diffusion model with mobile point-like sources and sinks.

Dynamic flux balance analysis with nonlinear objective function.

Editorial: Synthetic biology--ready for application.

Effective Production of (S)-α-Hydroxy ketones: An Reaction Engineering Approach

Emerging Corynebacterium glutamicum systems biology

Engineering of Corynebacterium glutamicum for minimized carbon loss during utilization of D-xylose containing substrates

Error propagation analysis for quantitative intracellular metabolomics

Experimental design principles for isotopically instationary 13C labeling experiments

Extensive exometabolome analysis reveals extended overflow metabolism in various microorganisms

Fast and reliable strain characterization of Streptomyces lividans through micro-scale cultivation.

FeedER: a feedback-regulated enzyme-based slow-release system for fed-batch cultivation in microtiter plates

First- and second-order parameter sensitivities of a metabolically and isotopically non-stationary biochemical network model

Fluxomics: mass spectrometry versus quantitative imaging

From stationary to instationary metabolic flux analysis

Generic Protocol for Optimization of Heterologous Protein Production Using Automated Microbioreactor Technology

Germination and Growth Analysis of at the Single-Cell Level Under Varying Medium Compositions

Homogenizing bacterial cell factories: Analysis and engineering of phenotypic heterogeneity.

How to measure metabolic fluxes: a taxonomic guide for (13)C fluxomics

Hydroxynitrile Lyase from Arabidopsis thaliana: Identification of Reaction Parameters for Enantiopure Cyanohydrin Synthesis by Pure and Immobilized Catalyst

Image-Based Single Cell Profiling: High-Throughput Processing of Mother Machine Experiments.

Improved microscale cultivation of Pichia pastoris for clonal screening.

Influence of Organic Solvents on Enzymatic Asymmetric Carboligations

Interpretation of metabolic flux maps by limitation potentials and constrained limitation sensitivities

Investigating the dynamic behavior of biochemical networks using model families

Isotopically non-stationary metabolic flux analysis: complex yet highly informative

Kriging with trend functions nonlinear in their parameters: Theory and application in enzyme kinetics

Laboratory-scale photobiotechnology-current trends and future perspectives.

Less sacrifice, more insight: Repeated low-volume sampling of microbioreactor cultivations enables accelerated deep phenotyping of microbial strain libraries

Light-responsive control of bacterial gene expression: precise triggering of the lac promoter activity using photocaged IPTG.

Live cell imaging of SOS and prophage dynamics in isogenic bacterial populations