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Lista de obras de Hediye Erdjument-Bromage

A CK2-dependent mechanism for degradation of the PML tumor suppressor

artículo científico publicado en 2006

A Drosophila Polycomb group complex includes Zeste and dTAFII proteins.

artículo científico publicado en 2001

A Rad26-Def1 complex coordinates repair and RNA pol II proteolysis in response to DNA damage

artículo científico publicado en 2002

A Rsc3/Rsc30 zinc cluster dimer reveals novel roles for the chromatin remodeler RSC in gene expression and cell cycle control

artículo científico publicado en 2001

A complex of the Srb8, -9, -10, and -11 transcriptional regulatory proteins from yeast

artículo científico publicado en 2002

A cyclin-dependent kinase-activating kinase (CAK) in budding yeast unrelated to vertebrate CAK.

artículo científico publicado en 1996

A direct interaction between the RAG2 C terminus and the core histones is required for efficient V(D)J recombination

artículo científico publicado en 2005

A glutathione S-transferase (GST) isozyme from broccoli with significant sequence homology to the mammalian theta-class of GSTs

artículo científico publicado en 1994

A histone H2A deubiquitinase complex coordinating histone acetylation and H1 dissociation in transcriptional regulation

artículo científico publicado en 2007

A human telomeric protein

artículo científico publicado en 1995

A new role for Nogo as a regulator of vascular remodeling

artículo científico publicado en 2004

A novel SH2-containing phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase (SHIP2) is constitutively tyrosine phosphorylated and associated with src homologous and collagen gene (SHC) in chronic myelogenous leukemia progenitor cells

artículo científico publicado en 1999

A novel histone acetyltransferase is an integral subunit of elongating RNA polymerase II holoenzyme

artículo científico publicado en 1999

A novel protein complex that interacts with the vitamin D3 receptor in a ligand-dependent manner and enhances VDR transactivation in a cell-free system

artículo científico publicado en 1998

A novel requirement for DROSHA in maintenance of mammalian CG methylation

artículo científico publicado en 2017

A protein complex containing Tho2, Hpr1, Mft1 and a novel protein, Thp2, connects transcription elongation with mitotic recombination in Saccharomyces cerevisiae

artículo científico publicado en 2000

A semisynthetic Eph receptor tyrosine kinase provides insight into ligand-induced kinase activation

artículo científico publicado en 2011

ASAP, a novel protein complex involved in RNA processing and apoptosis

artículo científico publicado en 2003

ATP hydrolysis-dependent disassembly of the 26S proteasome is part of the catalytic cycle

artículo científico publicado en 2005

Activated ADP-ribosylation Factor Assembles Distinct Pools of Actin on Golgi Membranes

artículo científico publicado en 2000

Adhesion signaling by a novel mitotic substrate of src kinases

artículo científico publicado en 2005

Adipocyte-specific transcription factor ARF6 is a heterodimeric complex of two nuclear hormone receptors, PPAR gamma and RXR alpha

artículo científico publicado en 1994

Affinity purification probes of potential use to investigate the endogenous Hsp70 interactome in cancer

artículo científico publicado en 2014

Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90

artículo científico publicado en 2011

Aminopeptidase activities as prospective urinary biomarkers for bladder cancer

artículo científico publicado en 2014

An ikaros-containing chromatin-remodeling complex in adult-type erythroid cells

artículo científico publicado en 2000

An iron delivery pathway mediated by a lipocalin

artículo científico publicado en 2002

Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation

artículo científico publicado en 1999

Architecture of the Mediator head module

artículo científico publicado en 2011

Artemis C-terminal region facilitates V(D)J recombination through its interactions with DNA Ligase IV and DNA-PKcs

artículo científico publicado en 2012

BAFF controls B cell metabolic fitness through a PKC beta- and Akt-dependent mechanism

artículo científico publicado en 2006

Brd4 links chromatin targeting to HPV transcriptional silencing

artículo científico publicado en 2006

Bromodomain protein 7 interacts with PRMT5 and PRC2, and is involved in transcriptional repression of their target genes

artículo científico publicado en 2011

CHMP5 is essential for late endosome function and down-regulation of receptor signaling during mouse embryogenesis

scientific journal article

COMPASS: a complex of proteins associated with a trithorax-related SET domain protein

artículo científico publicado en 2001

Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death

scientific journal article

Catalytic properties of ADAM19

artículo científico publicado en 2003

Cleavage and proteasome-mediated degradation of the basal transcription factor TFIIA.

artículo científico publicado en 2004

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

artículo científico publicado en 1994

Cloning, heterologous expression, and distinct substrate specificity of protein farnesyltransferase from Trypanosoma brucei

artículo científico publicado en 2000

Coatomer-bound Cdc42 regulates dynein recruitment to COPI vesicles

artículo científico publicado en 2005

Communication between Distant Sites in RNA Polymerase II through Ubiquitylation Factors and the Polymerase CTD

article by Baggavalli P. Somesh et al published April 2007 in Cell

Composition of yeast snRNPs and snoRNPs in the absence of trimethylguanosine caps reveals nuclear cap binding protein as a gained U1 component implicated in the cold-sensitivity of tgs1Δ cells

artículo científico publicado en 2011

Conversion of proepithelin to epithelins: roles of SLPI and elastase in host defense and wound repair

artículo científico publicado en 2002

Cytosol-derived proteins are sufficient for Arp2/3 recruitment and ARF/coatomer-dependent actin polymerization on Golgi membranes

scientific journal article

DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA

artículo científico publicado en 2007

Defects in energy homeostasis in Leigh syndrome French Canadian variant through PGC-1alpha/LRP130 complex

artículo científico publicado en 2006

Demethylation of histone H3K36 and H3K9 by Rph1: a vestige of an H3K9 methylation system in Saccharomyces cerevisiae?

artículo científico publicado en 2007

Differential exoprotease activities confer tumor-specific serum peptidome patterns

artículo científico publicado en 2006

ERS-24, a mammalian v-SNARE implicated in vesicle traffic between the ER and the Golgi

artículo científico publicado en 1997

Elongator is a histone H3 and H4 acetyltransferase important for normal histone acetylation levels in vivo

artículo científico publicado en 2002

Enteric beta-defensin: molecular cloning and characterization of a gene with inducible intestinal epithelial cell expression associated with Cryptosporidium parvum infection.

artículo científico publicado en 1998

Evidence for a role of a tumor necrosis factor-alpha (TNF-alpha)-converting enzyme-like protease in shedding of TRANCE, a TNF family member involved in osteoclastogenesis and dendritic cell survival

artículo científico publicado en 1999

Examination of micro-tip reversed-phase liquid chromatographic extraction of peptide pools for mass spectrometric analysis

artículo científico publicado en 1998

Extramitochondrial cardiolipin suggests a novel function of mitochondria in spermatogenesis

artículo científico publicado en 2019

FENS-1 and DFCP1 are FYVE domain-containing proteins with distinct functions in the endosomal and Golgi compartments

artículo científico publicado en 2001

FK506 binding protein associated with the calcium release channel (ryanodine receptor)

artículo científico publicado el 15 de mayo de 1992

Fas-associated death domain (FADD) and the E3 ubiquitin-protein ligase TRIM21 interact to negatively regulate virus-induced interferon production

artículo científico publicado en 2010

Five members of a novel Ca(2+)-binding protein (CABP) subfamily with similarity to calmodulin

artículo científico publicado en 2000

GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR

scientific journal article

Genome-wide dynamics of SAPHIRE, an essential complex for gene activation and chromatin boundaries

artículo científico publicado en 2007

HDAC6 is a specific deacetylase of peroxiredoxins and is involved in redox regulation

artículo científico publicado en 2008

Heat shock protein 90 mediates macrophage activation by Taxol and bacterial lipopolysaccharide

artículo científico publicado en 1999

Hematopoiesis controlled by distinct TIF1gamma and Smad4 branches of the TGFbeta pathway

artículo científico publicado en 2006

Heterogeneous nuclear ribonucleoprotein L Is a subunit of human KMT3a/Set2 complex required for H3 Lys-36 trimethylation activity in vivo

artículo científico publicado en 2009

High-level expression of a full-length Eph receptor

artículo científico publicado en 2013

High-sensitivity sequencing of large proteins: partial structure of the rapamycin-FKBP12 target

artículo científico publicado en 1994

Highly efficient selenomethionine labeling of recombinant proteins produced in mammalian cells

artículo científico publicado en 2006

Histone H3 and H4 ubiquitylation by the CUL4-DDB-ROC1 ubiquitin ligase facilitates cellular response to DNA damage

artículo científico publicado en 2006

Histone deacetylases and SAP18, a novel polypeptide, are components of a human Sin3 complex

artículo científico publicado en 1997

Histone deimination antagonizes arginine methylation

artículo científico publicado en 2004

Histone demethylation by a family of JmjC domain-containing proteins

artículo científico publicado en 2006

Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein

artículo científico publicado en 2002

Human Mob proteins regulate the NDR1 and NDR2 serine-threonine kinases

artículo científico publicado en 2004

Human SWI/SNF-associated PRMT5 methylates histone H3 arginine 8 and negatively regulates expression of ST7 and NM23 tumor suppressor genes

artículo científico publicado en 2004

Human SirT1 interacts with histone H1 and promotes formation of facultative heterochromatin

artículo científico publicado en 2004

Identification and functional characterization of the p66/p68 components of the MeCP1 complex.

artículo científico publicado en 2002

Identification of ARAP3, a novel PI3K effector regulating both Arf and Rho GTPases, by selective capture on phosphoinositide affinity matrices

artículo científico publicado en 2002

Identification of a new class of protein kinases represented by eukaryotic elongation factor-2 kinase

artículo científico publicado en 1997

Identification of a putative effector protein for rab11 that participates in transferrin recycling

artículo científico publicado en 1999

Identification of an allosteric pocket on human hsp70 reveals a mode of inhibition of this therapeutically important protein

artículo científico publicado en 2013

Identification of new mediator subunits in the RNA polymerase II holoenzyme from Saccharomyces cerevisiae

artículo científico publicado en 1998

Induction of terminal differentiation in epithelial cells requires polymerization of hensin by galectin 3

scientific journal article

Inhibition of Hsp90 Suppresses PI3K/AKT/mTOR Signaling and Has Antitumor Activity in Burkitt Lymphoma

artículo científico publicado en 2017

Interleukin-3 signals through multiple isoforms of Stat5.

artículo científico publicado en 1995

Isolation and mass spectrometry of transcription factor complexes

artículo científico publicado en 2002

JAMP optimizes ERAD to protect cells from unfolded proteins

artículo científico publicado en 2008

JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor

artículo científico publicado en 2006

L3MBTL1, a histone-methylation-dependent chromatin lock

artículo científico publicado en 2007

L3MBTL2 protein acts in concert with PcG protein-mediated monoubiquitination of H2A to establish a repressive chromatin structure

artículo científico publicado en 2011

LRPPRC is necessary for polyadenylation and coordination of translation of mitochondrial mRNAs

artículo científico publicado en 2012

Ligand-dependent transcription activation by nuclear receptors requires the DRIP complex

artículo científico publicado en 1999

Lysine methylation within the globular domain of histone H3 by Dot1 is important for telomeric silencing and Sir protein association

artículo científico publicado en 2002

MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex

artículo científico publicado en 1999

MTERF2 is a nucleoid component in mammalian mitochondria

artículo científico publicado en 2009

MTERF3 is a negative regulator of mammalian mtDNA transcription

artículo científico publicado en 2007

MTERF4 regulates translation by targeting the methyltransferase NSUN4 to the mammalian mitochondrial ribosome

artículo científico publicado en 2011

Mammalian mediator of transcriptional regulation and its possible role as an end-point of signal transduction pathways

artículo científico publicado en 1998

Mapping of amino acid residues in the p34 subunit of human single-stranded DNA-binding protein phosphorylated by DNA-dependent protein kinase and Cdc2 kinase in vitro

artículo científico publicado en 1997

Merlin/NF2 Functions Upstream of the Nuclear E3 Ubiquitin Ligase CRL4DCAF1 to Suppress Oncogenic Gene Expression

article

Merlin/NF2 loss-driven tumorigenesis linked to CRL4(DCAF1)-mediated inhibition of the hippo pathway kinases Lats1 and 2 in the nucleus

artículo científico publicado en 2014

Merlin/NF2 suppresses tumorigenesis by inhibiting the E3 ubiquitin ligase CRL4(DCAF1) in the nucleus

artículo científico publicado en 2010

Metabolic enzymes of mycobacteria linked to antioxidant defense by a thioredoxin-like protein

artículo científico publicado en 2002

Metalloprotease-disintegrin MDC9: intracellular maturation and catalytic activity

artículo científico publicado en 1999

Metazoan Scc4 homologs link sister chromatid cohesion to cell and axon migration guidance

artículo científico publicado en 2006

Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domain

scientific journal article

Methylation of RUNX1 by PRMT1 abrogates SIN3A binding and potentiates its transcriptional activity

artículo científico publicado en 2008

Molecular cloning and characterization of (R)-3-hydroxybutyrate dehydrogenase from human heart

artículo científico publicado en 1992

Monoubiquitination of filamin B regulates vascular endothelial growth factor-mediated trafficking of histone deacetylase 7.

artículo científico publicado en 2013

Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation

artículo científico publicado en 2005

Multiple mechanisms confining RNA polymerase II ubiquitylation to polymerases undergoing transcriptional arrest

artículo científico publicado en 2005

Mutual targeting of mediator and the TFIIH kinase Kin28.

artículo científico publicado en 2004

Mycobacterium tuberculosis appears to lack alpha-ketoglutarate dehydrogenase and encodes pyruvate dehydrogenase in widely separated genes

scientific journal article

Myoferlin regulates vascular endothelial growth factor receptor-2 stability and function

scientific journal article

N-Terminal Amino Acid Sequence Determination of Proteins by N-Terminal Dimethyl Labeling: Pitfalls and Advantages When Compared with Edman Degradation Sequence Analysis

artículo científico publicado en 2016

NEDD4-1 is a proto-oncogenic ubiquitin ligase for PTEN

artículo científico publicado en 2007

NGAL (Lcn2) monomer is associated with tubulointerstitial damage in chronic kidney disease

artículo científico publicado en 2012

Nab2p and the Thp1p-Sac3p complex functionally interact at the interface between transcription and mRNA metabolism

artículo científico publicado en 2003

P-Rex1, a PtdIns(3,4,5)P3- and Gbetagamma-regulated guanine-nucleotide exchange factor for Rac

artículo científico publicado en 2002

PARP-1 determines specificity in a retinoid signaling pathway via direct modulation of mediator

artículo científico publicado en 2005

PLU-1 is an H3K4 demethylase involved in transcriptional repression and breast cancer cell proliferation

artículo científico publicado en 2007

PR-Set7 is a nucleosome-specific methyltransferase that modifies lysine 20 of histone H4 and is associated with silent chromatin

scientific journal article

PRC2 complexes with JARID2, MTF2, and esPRC2p48 in ES cells to modulate ES cell pluripotency and somatic cell reprogramming

artículo científico publicado en 2011

PRDM16 controls a brown fat/skeletal muscle switch

artículo científico publicado en 2008

PRMT4 blocks myeloid differentiation by assembling a methyl-RUNX1-dependent repressor complex

artículo científico publicado en 2013

PU.1 and a TTTAAA element in the myeloid defensin-1 promoter create an operational TATA box that can impose cell specificity onto TFIID function

artículo científico publicado en 2006

Parkinson's Disease-associated α-Synuclein Is a Calmodulin Substrate

artículo científico publicado en 2003

Peptide methionine sulfoxide reductase from Escherichia coli and Mycobacterium tuberculosis protects bacteria against oxidative damage from reactive nitrogen intermediates

scientific journal article

Phagocytosis in macrophages lacking Cbl reveals an unsuspected role for Fc gamma receptor signaling and actin assembly in target binding

artículo científico publicado en 2009

Pharmacologically controlling protein-protein interactions through epichaperomes for therapeutic vulnerability in cancer

scientific article published on 25 November 2021

Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis

artículo científico publicado en 2005

Phosphorylation of Thyroid Hormone Receptor-associated Nuclear Receptor Corepressor Holocomplex by the DNA-dependent Protein Kinase Enhances Its Histone Deacetylase Activity

artículo científico publicado en 2007

Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB

artículo científico publicado en 2009

Physical and functional interaction between Elongator and the chromatin-associated Kti12 protein

artículo científico publicado en 2005

Porin activity and sequence analysis of a 31-kilodalton Treponema pallidum subsp. pallidum rare outer membrane protein (Tromp1).

artículo científico publicado en 1995

Porin activity of the native and recombinant outer membrane protein Oms28 of Borrelia burgdorferi

artículo científico publicado en 1996

Processing of autophagic protein LC3 by the 20S proteasome

artículo científico publicado en 2010

Proteasome-mediated processing of Def1, a critical step in the cellular response to transcription stress

artículo científico publicado en 2013

Protein kinase B kinases that mediate phosphatidylinositol 3,4,5-trisphosphate-dependent activation of protein kinase B

scientific journal article

Proteolytic cleavage of MLL generates a complex of N- and C-terminal fragments that confers protein stability and subnuclear localization

artículo científico publicado en 2003

PtdIns(3)P regulates the neutrophil oxidase complex by binding to the PX domain of p40phox

article

Purification and characterization of the human elongator complex

artículo científico publicado en 2002

Purification and functional characterization of SET8, a nucleosomal histone H4-lysine 20-specific methyltransferase

artículo científico publicado en 2002

RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs

artículo científico publicado en 1994

RNA polymerase II elongator holoenzyme is composed of two discrete subcomplexes

artículo científico publicado en 2001

RSC, an essential, abundant chromatin-remodeling complex

artículo científico publicado en 1996

Recognition of trimethylated histone H3 lysine 4 facilitates the recruitment of transcription postinitiation factors and pre-mRNA splicing

artículo científico publicado en 2007

Regulation of 2-oxoglutarate (alpha-ketoglutarate) dehydrogenase stability by the RING finger ubiquitin ligase Siah

artículo científico publicado en 2004

Regulation of cell cycle progression and gene expression by H2A deubiquitination

artículo científico publicado en 2007

Regulation of post-Golgi vesicle production in an in vitro system

artículo científico publicado en 1995

Requirement of a corepressor for Dr1-mediated repression of transcription

artículo científico publicado en 1996

Retracted: SETDB1 Is Involved in Postembryonic DNA Methylation and Gene Silencing in Drosophila

artículo científico publicado en 2010

Reversal of RNA polymerase II ubiquitylation by the ubiquitin protease Ubp3.

artículo científico publicado en 2008

Revised subunit structure of yeast transcription factor IIH (TFIIH) and reconciliation with human TFIIH.

artículo científico publicado en 2003

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

artículo científico publicado en 2004

Role of hPHF1 in H3K27 methylation and Hox gene silencing

artículo científico publicado en 2008

Role of histone H2A ubiquitination in Polycomb silencing

artículo científico publicado en 2004

Role of histone H3 lysine 27 methylation in Polycomb-group silencing

artículo científico publicado en 2002

Role of integrins in the assembly and function of hensin in intercalated cells

artículo científico publicado en 2008

Role of the Sin3-histone deacetylase complex in growth regulation by the candidate tumor suppressor p33(ING1).

artículo científico publicado en 2002

S-nitroso proteome of Mycobacterium tuberculosis: Enzymes of intermediary metabolism and antioxidant defense

artículo científico publicado en 2004

SAP30, a novel protein conserved between human and yeast, is a component of a histone deacetylase complex

artículo científico publicado en 1998

SIRT1 regulates the histone methyl-transferase SUV39H1 during heterochromatin formation

artículo científico publicado en 2007

SNAP receptors implicated in vesicle targeting and fusion

artículo científico publicado en 1993

Schizosaccharomyces pombe carboxyl-terminal domain (CTD) phosphatase Fcp1: distributive mechanism, minimal CTD substrate, and active site mapping

artículo científico publicado en 2003

Sequence analysis and characterization of a 40-kilodalton Borrelia hermsii glycerophosphodiester phosphodiesterase homolog

artículo científico publicado en 1997

Sequence analysis and recombinant expression of a 28-kilodalton Treponema pallidum subsp. pallidum rare outer membrane protein (Tromp2).

artículo científico publicado en 1997

Set9, a novel histone H3 methyltransferase that facilitates transcription by precluding histone tail modifications required for heterochromatin formation

artículo científico publicado en 2002

Siah2 regulates stability of prolyl-hydroxylases, controls HIF1alpha abundance, and modulates physiological responses to hypoxia

artículo científico publicado en 2004

Superoxide dismutase 1 (SOD1) is a target for a small molecule identified in a screen for inhibitors of the growth of lung adenocarcinoma cell lines

artículo científico publicado en 2011

Suppression of mitochondrial respiration through recruitment of p160 myb binding protein to PGC-1alpha: modulation by p38 MAPK

artículo científico publicado en 2004

Synthesis of diphosphoinositol pentakisphosphate by a newly identified family of higher inositol polyphosphate kinases

artículo científico publicado en 1999

T-loop phosphorylation stabilizes the CDK7-cyclin H-MAT1 complex in vivo and regulates its CTD kinase activity

artículo científico publicado en 2001

TLR signalling augments macrophage bactericidal activity through mitochondrial ROS.

artículo científico publicado en 2011

TRIM3, a tumor suppressor linked to regulation of p21(Waf1/Cip1.).

artículo científico publicado en 2013

Tandem bromodomains in the chromatin remodeler RSC recognize acetylated histone H3 Lys14

artículo científico publicado en 2004

Targeting the Hsp90-associated viral oncoproteome in gammaherpesvirus-associated malignancies

artículo científico publicado en 2013

The C-terminal domain phosphatase and transcription elongation activities of FCP1 are regulated by phosphorylation

artículo científico publicado en 2003

The Drosophila fragile X protein functions as a negative regulator in the orb autoregulatory pathway

artículo científico publicado en 2005

The G beta gamma sensitivity of a PI3K is dependent upon a tightly associated adaptor, p101

scientific journal article

The H3K4 demethylase lid associates with and inhibits histone deacetylase Rpd3

artículo científico publicado en 2009

The HSA domain binds nuclear actin-related proteins to regulate chromatin-remodeling ATPases

artículo científico publicado en 2008

The Hsp70-Ydj1 molecular chaperone represses the activity of the heme activator protein Hap1 in the absence of heme

artículo científico publicado en 2001

The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain

artículo científico publicado en 1998

The Oms66 (p66) protein is a Borrelia burgdorferi porin.

artículo científico publicado en 1997

The RNA processing exosome is linked to elongating RNA polymerase II in Drosophila

artículo científico publicado en 2002

The RSC chromatin remodeling complex bears an essential fungal-specific protein module with broad functional roles

artículo científico publicado en 2006

The Ubiquitination of PINK1 Is Restricted to Its Mature 52-kDa Form

artículo científico publicado en 2017

The Yaf9 component of the SWR1 and NuA4 complexes is required for proper gene expression, histone H4 acetylation, and Htz1 replacement near telomeres

artículo científico publicado en 2004

The budding yeast Rad9 checkpoint complex: chaperone proteins are required for its function

artículo científico publicado en 2003

The core of the polycomb repressive complex is compositionally and functionally conserved in flies and humans

artículo científico publicado en 2002

The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction

artículo científico publicado en 2020

The histone chaperone TAF-I/SET/INHAT is required for transcription in vitro of chromatin templates

artículo científico publicado en 2005

The histone variant MacroH2A1 regulates target gene expression in part by recruiting the transcriptional coregulator PELP1.

artículo científico publicado en 2014

The human PAF complex coordinates transcription with events downstream of RNA synthesis

artículo científico publicado en 2005

The laminin receptor modulates granulocyte-macrophage colony-stimulating factor receptor complex formation and modulates its signaling

artículo científico publicado en 2003

The novel ubiquitin ligase complex, SCF(Fbxw4), interacts with the COP9 signalosome in an F-box dependent manner, is mutated, lost and under-expressed in human cancers

artículo científico publicado en 2013

The overlapping host responses to bacterial cyclic dinucleotides

artículo científico publicado en 2011

The retinoblastoma binding protein RBP2 is an H3K4 demethylase

artículo científico

The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36.

artículo científico publicado en 2006

The trithorax-group protein Lid is a histone H3 trimethyl-Lys4 demethylase

artículo científico publicado en 2007

The ubiquitous subunit of erythroid transcription factor NF-E2 is a small basic-leucine zipper protein related to the v-maf oncogene

artículo científico publicado en 1993

The yeast capping enzyme represses RNA polymerase II transcription

artículo científico publicado en 2002

Tissue inhibitor of metalloproteinase-2 stimulates mesenchymal growth and regulates epithelial branching during morphogenesis of the rat metanephros

artículo científico publicado en 1999

Tissue-specific and developmental stage-specific DNA binding by a mammalian SWI/SNF complex associated with human fetal-to-adult globin gene switching

artículo científico publicado en 1999

Two actin-related proteins are shared functional components of the chromatin-remodeling complexes RSC and SWI/SNF.

artículo científico publicado en 1998

Two functionally distinct forms of the RSC nucleosome-remodeling complex, containing essential AT hook, BAH, and bromodomains

artículo científico publicado en 1999

USP49 deubiquitinates histone H2B and regulates cotranscriptional pre-mRNA splicing

artículo científico publicado en 2013

Ubiquitin ligase Nedd4L targets activated Smad2/3 to limit TGF-beta signaling

artículo científico publicado en 2009

Ubiquitination regulates PTEN nuclear import and tumor suppression

artículo científico publicado en 2007

Ubiquitination, localization, and stability of an anti-apoptotic BCL2-like protein, BCL2L10/BCLb, are regulated by Ubiquilin1.

artículo científico publicado en 2012

Ubiquitylation of histone H2B controls RNA polymerase II transcription elongation independently of histone H3 methylation

artículo científico publicado en 2007

Unique Transcriptional Programs Identify Subtypes of AKI.

artículo científico publicado en 2016

WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity

artículo científico publicado en 2009

mAM facilitates conversion by ESET of dimethyl to trimethyl lysine 9 of histone H3 to cause transcriptional repression

artículo científico publicado en 2003

mSin3A/histone deacetylase 2- and PRMT5-containing Brg1 complex is involved in transcriptional repression of the Myc target gene cad

artículo científico publicado en 2003

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

artículo científico publicado en 2002

Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex

artículo científico publicado en 2008