Lista de obras - Maree Smith - Dominio Público Uruguay

A novel fully validated LC–MS/MS method for quantification of pyridoxal-5′-phosphate concentrations in samples of human whole blood

artículo científico publicado en 2015

A randomized, controlled trial of oxycodone versus placebo in patients with postherpetic neuralgia and painful diabetic neuropathy treated with pregabalin

artículo científico publicado en 2009

A small molecule angiotensin II type 2 receptor (AT₂R) antagonist produces analgesia in a rat model of neuropathic pain by inhibition of p38 mitogen-activated protein kinase (MAPK) and p44/p42 MAPK activation in the dorsal root ganglia.

artículo científico publicado en 2013

ASAP ECMO: Antibiotic, Sedative and Analgesic Pharmacokinetics during Extracorporeal Membrane Oxygenation: a multi-centre study to optimise drug therapy during ECMO.

artículo científico publicado en 2012

Altered antibiotic pharmacokinetics during extracorporeal membrane oxygenation: cause for concern?

article

Analgesic efficacy and mode of action of a selective small molecule angiotensin II type 2 receptor antagonist in a rat model of prostate cancer-induced bone pain.

artículo científico publicado en 2013

Analgesic efficacy of small-molecule angiotensin II type 2 receptor antagonists in a rat model of antiretroviral toxic polyneuropathy

artículo científico publicado en 2014

Angiotensin II type 2-receptor: new clinically validated target in the treatment of neuropathic pain

artículo científico publicado en 2014

Anti-allodynic efficacy of the chi-conopeptide, Xen2174, in rats with neuropathic pain

artículo científico publicado en 2005

Antinociception versus serum concentration relationships following acute administration of intravenous morphine in male and female Sprague-Dawley rats: differences between the tail flick and hot plate nociceptive tests

artículo científico publicado en 2008

Assessment of the anti-allodynic efficacy of a glycine transporter 2 inhibitor relative to pregabalin and duloxetine in a rat model of prostate cancer-induced bone pain

artículo científico publicado en 2020

Assessment of the anti-hyperalgesic efficacy of J-2156, relative to clinically available analgesic/adjuvant agents in a rat model of mild to moderate chronic mechanical low back pain (LBP)

artículo científico publicado en 2020

Bioavailability and pharmacokinetics of phenytoin during pregnancy

artículo científico publicado en 1984

Cerebrospinal fluid and plasma concentrations of morphine, morphine-3-glucuronide, and morphine-6-glucuronide in patients before and after initiation of intracerebroventricular morphine for cancer pain management.

artículo científico publicado en 1999

Characterisation of a rat model of mechanical low back pain at an advanced stage using immunohistochemical methods

artículo científico publicado en 2020

Characterization of non-conventional opioid binding sites in rat and human lung

artículo científico publicado en 1994

Chronic propranolol administration during pregnancy

artículo científico publicado en 1983

Co-administration of oxycodone and morphine and analgesic synergy re-examined

artículo científico publicado en 2005

Co-administration of sub-antinociceptive doses of oxycodone and morphine produces marked antinociceptive synergy with reduced CNS side-effects in rats

artículo científico publicado en 2000

Comment on “protective arms of the renin‐angiotensin system in neurological disease” ⬇️

artículo científico publicado el 1 de noviembre de 2013

Comments on Goucke et al., PAIN, 56 (1994) 145-149.

artículo científico publicado en 1994

Comparative analgesic efficacy of pregabalin administered according to either a prevention protocol or an intervention protocol in rats with cisplatin-induced peripheral neuropathy

scientific article published on 28 June 2018

Comparative oxycodone pharmacokinetics in humans after intravenous, oral, and rectal administration

artículo científico publicado en 1992

Comparative studies of the neuro-excitatory behavioural effects of morphine-3-glucuronide and dynorphin A(2-17) following spinal and supraspinal routes of administration

artículo científico publicado en 2009

Comparative studies using the Morris water maze to assess spatial memory deficits in two transgenic mouse models of Alzheimer's disease

artículo científico publicado en 2014

Comparison of Burrowing and Stimuli-Evoked Pain Behaviors as End-Points in Rat Models of Inflammatory Pain and Peripheral Neuropathic Pain.

artículo científico publicado en 2016

Comparison of the pharmacokinetics of oxycodone and noroxycodone in male dark agouti and Sprague--Dawley rats: influence of streptozotocin-induced diabetes

artículo científico publicado en 2005

Correlations between in vitro dissolution, in vivo bioavailability and hypoglycaemic effect of oral glibenclamide

artículo científico publicado en 1986

Corrigendum: Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere

artículo científico publicado en 2018

Countering opioid-induced respiratory depression by non-opioids that are respiratory stimulants

artículo científico publicado en 2020

Current developments in MRI for assessing rodent models of multiple sclerosis

Cyclooctatetraene: A Bioactive Cubane Paradigm Complement

scientific article published on 25 January 2019

Deletion of guanine nucleotide binding protein alpha z subunit in mice induces a gene dose dependent tolerance to morphine.

artículo científico publicado en 2004

Determination of the Serum Protein Binding of Oxycodone and Morphine Using Ultrafiltration

artículo científico publicado en 1993

Development and validation of a sensitive solid-phase-extraction (SPE) method using high-performance liquid chromatography/tandem mass spectrometry (LC–MS/MS) for determination of risedronate concentrations in human plasma

article

Differences between and combinations of opioids re-visited

artículo científico publicado en 2008

Effects of morphine-3-glucuronide and morphine on the K+-evoked release of [3H]-glutamic acid and [14C]-gamma-aminobutyric acid from rat brain synaptosomes

artículo científico publicado en 1996

Endomorphin analogues with mixed μ-opioid (MOP) receptor agonism/δ-opioid (DOP) receptor antagonism and lacking β-arrestin2 recruitment activity

artículo científico publicado en 2014

Establishment and characterisation of a stavudine (d4T)-induced rat model of antiretroviral toxic neuropathy (ATN) using behavioural and pharmacological methods

artículo científico publicado en 2019

Establishment and characterization of an optimized mouse model of multiple sclerosis-induced neuropathic pain using behavioral, pharmacologic, histologic and immunohistochemical methods

artículo científico publicado en 2014

Evaluation of a High-Throughput Peptide Reactivity Format Assay for Assessment of the Skin Sensitization Potential of Chemicals

artículo científico publicado en 2016

Formulation of Bioerodible Ketamine Microparticles as an Analgesic Adjuvant Treatment Produced by Supercritical Fluid Polymer Encapsulation

scholarly article by Felicity Y Han et al published 6 December 2018 in Pharmaceutics

Fully validated LC–MS/MS method for quantification of homocysteine concentrations in samples of human serum: A new approach

scientific article published on 02 October 2014

High-throughput assay for simultaneous quantification of the plasma concentrations of morphine, fentanyl, midazolam and their major metabolites using automated SPE coupled to LC-MS/MS.

artículo científico publicado en 2012

Hydromorphone-3-glucuronide: a more potent neuro-excitant than its structural analogue, morphine-3-glucuronide.

artículo científico publicado en 2001

Hydromorphone-3-glucuronide: biochemical synthesis and preliminary pharmacological evaluation

artículo científico publicado en 1998

Improved One-Step Solid-Phase Extraction Method for Morphine, Morphine-3-Glucuronide, and Morphine-6-Glucuronide From Plasma and Quantitation Using High-Performance Liquid Chromatography With Electrochemical Detection

artículo científico publicado en 1998

In vitro methods for hazard assessment of industrial chemicals - opportunities and challenges

artículo científico publicado en 2015

In vivo high angular resolution diffusion-weighted imaging of mouse brain at 16.4 Tesla

artículo científico publicado en 2015

In vivo profiling of four centrally administered opioids for antinociception, constipation and respiratory depression: Between-colony differences in Sprague Dawley rats

artículo científico publicado en 2018

In vivo profiling of seven common opioids for antinociception, constipation and respiratory depression: no two opioids have the same profile

artículo científico publicado en 2014

Insulin implants prevent the temporal development of mechanical allodynia and opioid hyposensitivity for 24-wks in streptozotocin (STZ)-diabetic Wistar rats

artículo científico publicado en 2011

Intraarticular and periarticular opioid binding in inflamed tissue in experimental canine arthritis

artículo científico publicado en 1999

Investigation of the antinociceptive efficacy and relative potency of extended duration injectable 3-acylmorphine-6-sulfate prodrugs in rats

Lipo-endomorphin-1 derivatives with systemic activity against neuropathic pain without producing constipation

artículo científico publicado en 2012

Longitudinal Study of Painful Diabetic Neuropathy in the Zucker Diabetic Fatty Rat Model of Type 2 Diabetes: Impaired Basal G-Protein Activity Appears to Underpin Marked Morphine Hyposensitivity at 6 Months

article

Low-level quantitation of oxycodone and its oxidative metabolites, noroxycodone, and oxymorphone, in rat plasma by high-performance liquid chromatography–electrospray ionization–tandem mass spectrometry

scientific article published on 13 November 2006

Measurement of intracellular Ca2+ in cultured rat embryonic hippocampal neurons using a fluorescence microplate reader: potential application to biomolecular screening

artículo científico publicado en 2004

Metabolism of propranolol in the human maternal-placental-foetal unit

article

Morphine has a dual concentration-dependent effect on K(+)-evoked substance P release from rat peripheral airways

artículo científico publicado en 1997

Morphine hyposensitivity in streptozotocin-diabetic rats: Reversal by dietary l-arginine treatment

artículo científico publicado en 2017

Morphine-3-glucuronide's neuro-excitatory effects are mediated via indirect activation of N-methyl-D-aspartic acid receptors: mechanistic studies in embryonic cultured hippocampal neurones

artículo científico publicado en 2003

Morphine-3-glucuronide--a potent antagonist of morphine analgesia

artículo científico publicado en 1990

Morphine-3-glucuronide: evidence to support its putative role in the development of tolerance to the antinociceptive effects of morphine in the rat

article

Multiple sclerosis-induced neuropathic pain: pharmacological management and pathophysiological insights from rodent EAE models

artículo científico publicado en 2014

Neurotrophins and Neuropathic Pain: Role in Pathobiology

artículo científico publicado en 2015

Nitric oxide modulates μ-opioid receptor function in vitro

scientific article published on 14 April 2019

Novel Source of Ubiquitous Phthalates as Analytical Contaminant ⬇️

artículo científico publicado el 1 de marzo de 1981

Novel polymeric bioerodable microparticles for prolonged-release intrathecal delivery of analgesic agents for relief of intractable cancer-related pain

artículo científico publicado en 2015

Optimization and characterization of a rat model of prostate cancer-induced bone pain using behavioral, pharmacological, radiological, histological and immunohistochemical methods.

artículo científico publicado en 2013

Optimization and pharmacological characterization of a refined cisplatin-induced rat model of peripheral neuropathic pain

article

Oxycodone and morphine have distinctly different pharmacological profiles: radioligand binding and behavioural studies in two rat models of neuropathic pain

artículo científico publicado en 2007

Oxycodone has a distinctly different pharmacology from morphine

scholarly article by Maree Smith et al published December 2001 in European Journal of Pain

Oxycodone???s Mechanism of Action and Potency Differences after Spinal and Systemic Routes of Administration

artículo científico publicado en 2007

PG545, a dual heparanase and angiogenesis inhibitor, induces potent anti-tumour and anti-metastatic efficacy in preclinical models

artículo científico publicado en 2011

Pain, analgesia and genetics ⬇️

artículo científico publicado el 19 de agosto de 2011

Pathobiology and management of prostate cancer-induced bone pain: recent insights and future treatments ⬇️

artículo científico publicado el 6 de agosto de 2013

Pathobiology of cancer chemotherapy-induced peripheral neuropathy (CIPN).

artículo científico publicado en 2013

Peripherally acting novel lipo-endomorphin-1 peptides in neuropathic pain without producing constipation

artículo científico publicado en 2013

Pharmacokinetic changes in patients receiving extracorporeal membrane oxygenation

artículo científico publicado en 2012

Pharmacokinetics and pharmacodynamics of oxycodone when given intravenously and rectally to adult patients with cancer pain

artículo científico publicado en 1995

Pharmacokinetics of midazolam in the aged

artículo científico publicado en 1984

Pharmacokinetics of prazepam in man.

artículo científico publicado en 1979

Pregabalin for the treatment of fibromyalgia

artículo científico

Pregabalin in severe burn injury pain: A double-blind, randomised placebo-controlled trial

scientific article published on 12 March 2011

Preliminary study of the plasma and cerebrospinal fluid concentrations of IL-6 and IL-10 in patients with chronic pain receiving intrathecal opioid infusions by chronically implanted pump for pain management

artículo científico publicado en 2010

Propranolol in Pregnancy Three Year Prospective Study

artículo científico publicado en 1983

Quantitation of Morphine, Morphine-3-Glucuronide, and Morphine-6-Glucuronide in Plasma and Cerebrospinal Fluid Using Solid-Phase Extraction and High-Performance Liquid Chromatography with Electrochemical Detection

artículo científico publicado en 1994

Quantitation of Oxycodone in Human Plasma Using High-Performance Liquid Chromatography with Electrochemical Detection

artículo científico publicado en 1991

Quantitative autoradiography of peripheral opioid binding sites in rat lung

artículo científico publicado en 1996

Selective small molecule angiotensin II type 2 receptor antagonists for neuropathic pain: preclinical and clinical studies

artículo científico publicado en 2016

Sequestration of drugs in the circuit may lead to therapeutic failure during extracorporeal membrane oxygenation

artículo científico publicado en 2012

Sex differences in the pharmacokinetics, oxidative metabolism and oral bioavailability of oxycodone in the Sprague-Dawley rat.

artículo científico publicado en 2007

Simultaneous determination of morphine, oxycodone, morphine-3-glucuronide, and noroxycodone concentrations in rat serum by high performance liquid chromatography-electrospray ionization-tandem mass spectrometry

artículo científico publicado en 2005

Small molecule angiotensin II type 2 receptor (AT₂R) antagonists as novel analgesics for neuropathic pain: comparative pharmacokinetics, radioligand binding, and efficacy in rats

artículo científico publicado en 2013

Solid-phase extraction method with high-performance liquid chromatography and electrochemical detection for the quantitative analysis of oxycodone in human plasma

artículo científico publicado en 1998

Studies with ketamine and alfentanil following Freund's complete adjuvant-induced inflammation in rats.

artículo científico publicado en 2007

Study Protocol for a Pilot, Open-Label, Prospective, and Observational Study to Evaluate the Pharmacokinetics of Drugs Administered to Patients during Extracorporeal Circulation; Potential of In Vivo Cytochrome P450 Phenotyping to Optimise Pharmacot

scientific article published on 13 May 2019

Synthesis and biological evaluation of an orally active glycosylated endomorphin-1.

artículo científico publicado en 2012

Targeting angiotensin II type 2 receptor pathways to treat neuropathic pain and inflammatory pain.

artículo científico publicado en 2014

The ECMO PK Project: an incremental research approach to advance understanding of the pharmacokinetic alterations and improve patient outcomes during extracorporeal membrane oxygenation

artículo científico publicado en 2013

The antinociceptive potencies of oxycodone, noroxycodone and morphine after intracerebroventricular administration to rats

artículo científico publicado en 1994

The cubane paradigm in bioactive molecule discovery: further scope, limitations and the cyclooctatetraene complement

scientific article published on 01 July 2019

The excitatory effects of morphine-3-glucuronide are attenuated by LY274614, a competitive NMDA receptor antagonist, and by midazolam, an agonist at the benzodiazepine site on the GABAA receptor complex

artículo científico publicado en 1994

The furoxan nitric oxide donor, PRG150, evokes dose-dependent analgesia in a rat model of painful diabetic neuropathy

article

The intrinsic antinociceptive effects of oxycodone appear to be κ -opioid receptor mediated ⬇️

artículo científico publicado el 1 de noviembre de 1997

The neuroexcitatory morphine metabolite, morphine-3-glucuronide (M3G), is not neurotoxic in primary cultures of either hippocampal or cerebellar granule neurones

artículo científico publicado en 2003

The novel N-type calcium channel blocker, AM336, produces potent dose-dependent antinociception after intrathecal dosing in rats and inhibits substance P release in rat spinal cord slices

artículo científico publicado en 2002

The pharmacokinetics of midazolam in man.

artículo científico publicado en 1981

The role of morphine-6-glucuronide (M6G) in pain control

The streptozotocin-diabetic rat as a model of the chronic complications of human diabetes

artículo científico publicado en 2003

Theoretical and practical applications of the intracerebroventricular route for CSF sampling and drug administration in CNS drug discovery research: a mini review

artículo científico publicado en 2014

Topical application of a novel oxycodone gel formulation (tocopheryl phosphate mixture) in a rat model of peripheral inflammatory pain produces localized pain relief without significant systemic exposure

artículo científico publicado en 2015

Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere.

artículo científico publicado en 2016

Ventilatory responses of healthy subjects to intravenous combinations of morphine and oxycodone under imposed hypercapnic and hypoxaemic conditions

artículo científico publicado en 2005

chi-Conopeptide pharmacophore development: toward a novel class of norepinephrine transporter inhibitor (Xen2174) for pain

artículo científico publicado en 2009

Lista de obras de Maree Smith

A novel fully validated LC–MS/MS method for quantification of pyridoxal-5′-phosphate concentrations in samples of human whole blood

A randomized, controlled trial of oxycodone versus placebo in patients with postherpetic neuralgia and painful diabetic neuropathy treated with pregabalin

A small molecule angiotensin II type 2 receptor (AT₂R) antagonist produces analgesia in a rat model of neuropathic pain by inhibition of p38 mitogen-activated protein kinase (MAPK) and p44/p42 MAPK activation in the dorsal root ganglia.

ASAP ECMO: Antibiotic, Sedative and Analgesic Pharmacokinetics during Extracorporeal Membrane Oxygenation: a multi-centre study to optimise drug therapy during ECMO.

Altered antibiotic pharmacokinetics during extracorporeal membrane oxygenation: cause for concern?

Analgesic efficacy and mode of action of a selective small molecule angiotensin II type 2 receptor antagonist in a rat model of prostate cancer-induced bone pain.

Analgesic efficacy of small-molecule angiotensin II type 2 receptor antagonists in a rat model of antiretroviral toxic polyneuropathy

Angiotensin II type 2-receptor: new clinically validated target in the treatment of neuropathic pain

Anti-allodynic efficacy of the chi-conopeptide, Xen2174, in rats with neuropathic pain

Antinociception versus serum concentration relationships following acute administration of intravenous morphine in male and female Sprague-Dawley rats: differences between the tail flick and hot plate nociceptive tests

Assessment of the anti-allodynic efficacy of a glycine transporter 2 inhibitor relative to pregabalin and duloxetine in a rat model of prostate cancer-induced bone pain

Assessment of the anti-hyperalgesic efficacy of J-2156, relative to clinically available analgesic/adjuvant agents in a rat model of mild to moderate chronic mechanical low back pain (LBP)

Bioavailability and pharmacokinetics of phenytoin during pregnancy

Cerebrospinal fluid and plasma concentrations of morphine, morphine-3-glucuronide, and morphine-6-glucuronide in patients before and after initiation of intracerebroventricular morphine for cancer pain management.

Characterisation of a rat model of mechanical low back pain at an advanced stage using immunohistochemical methods

Characterization of non-conventional opioid binding sites in rat and human lung

Chronic propranolol administration during pregnancy

Co-administration of oxycodone and morphine and analgesic synergy re-examined

Co-administration of sub-antinociceptive doses of oxycodone and morphine produces marked antinociceptive synergy with reduced CNS side-effects in rats

Comment on “protective arms of the renin‐angiotensin system in neurological disease” ⬇️

Comments on Goucke et al., PAIN, 56 (1994) 145-149.

Comparative analgesic efficacy of pregabalin administered according to either a prevention protocol or an intervention protocol in rats with cisplatin-induced peripheral neuropathy

Comparative oxycodone pharmacokinetics in humans after intravenous, oral, and rectal administration

Comparative studies of the neuro-excitatory behavioural effects of morphine-3-glucuronide and dynorphin A(2-17) following spinal and supraspinal routes of administration

Comparative studies using the Morris water maze to assess spatial memory deficits in two transgenic mouse models of Alzheimer's disease

Comparison of Burrowing and Stimuli-Evoked Pain Behaviors as End-Points in Rat Models of Inflammatory Pain and Peripheral Neuropathic Pain.

Comparison of the pharmacokinetics of oxycodone and noroxycodone in male dark agouti and Sprague--Dawley rats: influence of streptozotocin-induced diabetes

Correlations between in vitro dissolution, in vivo bioavailability and hypoglycaemic effect of oral glibenclamide

Corrigendum: Validating Eaton's Hypothesis: Cubane as a Benzene Bioisostere

Countering opioid-induced respiratory depression by non-opioids that are respiratory stimulants

Current developments in MRI for assessing rodent models of multiple sclerosis

Cyclooctatetraene: A Bioactive Cubane Paradigm Complement

Deletion of guanine nucleotide binding protein alpha z subunit in mice induces a gene dose dependent tolerance to morphine.

Determination of the Serum Protein Binding of Oxycodone and Morphine Using Ultrafiltration

Development and validation of a sensitive solid-phase-extraction (SPE) method using high-performance liquid chromatography/tandem mass spectrometry (LC–MS/MS) for determination of risedronate concentrations in human plasma

Differences between and combinations of opioids re-visited

Effects of morphine-3-glucuronide and morphine on the K+-evoked release of [3H]-glutamic acid and [14C]-gamma-aminobutyric acid from rat brain synaptosomes

Endomorphin analogues with mixed μ-opioid (MOP) receptor agonism/δ-opioid (DOP) receptor antagonism and lacking β-arrestin2 recruitment activity

Establishment and characterisation of a stavudine (d4T)-induced rat model of antiretroviral toxic neuropathy (ATN) using behavioural and pharmacological methods

Establishment and characterization of an optimized mouse model of multiple sclerosis-induced neuropathic pain using behavioral, pharmacologic, histologic and immunohistochemical methods

Evaluation of a High-Throughput Peptide Reactivity Format Assay for Assessment of the Skin Sensitization Potential of Chemicals

Formulation of Bioerodible Ketamine Microparticles as an Analgesic Adjuvant Treatment Produced by Supercritical Fluid Polymer Encapsulation

Fully validated LC–MS/MS method for quantification of homocysteine concentrations in samples of human serum: A new approach

High-throughput assay for simultaneous quantification of the plasma concentrations of morphine, fentanyl, midazolam and their major metabolites using automated SPE coupled to LC-MS/MS.

Hydromorphone-3-glucuronide: a more potent neuro-excitant than its structural analogue, morphine-3-glucuronide.

Hydromorphone-3-glucuronide: biochemical synthesis and preliminary pharmacological evaluation

Improved One-Step Solid-Phase Extraction Method for Morphine, Morphine-3-Glucuronide, and Morphine-6-Glucuronide From Plasma and Quantitation Using High-Performance Liquid Chromatography With Electrochemical Detection

In vitro methods for hazard assessment of industrial chemicals - opportunities and challenges

In vivo high angular resolution diffusion-weighted imaging of mouse brain at 16.4 Tesla

In vivo profiling of four centrally administered opioids for antinociception, constipation and respiratory depression: Between-colony differences in Sprague Dawley rats

In vivo profiling of seven common opioids for antinociception, constipation and respiratory depression: no two opioids have the same profile

Insulin implants prevent the temporal development of mechanical allodynia and opioid hyposensitivity for 24-wks in streptozotocin (STZ)-diabetic Wistar rats

Intraarticular and periarticular opioid binding in inflamed tissue in experimental canine arthritis

Investigation of the antinociceptive efficacy and relative potency of extended duration injectable 3-acylmorphine-6-sulfate prodrugs in rats

Lipo-endomorphin-1 derivatives with systemic activity against neuropathic pain without producing constipation

Longitudinal Study of Painful Diabetic Neuropathy in the Zucker Diabetic Fatty Rat Model of Type 2 Diabetes: Impaired Basal G-Protein Activity Appears to Underpin Marked Morphine Hyposensitivity at 6 Months

Low-level quantitation of oxycodone and its oxidative metabolites, noroxycodone, and oxymorphone, in rat plasma by high-performance liquid chromatography–electrospray ionization–tandem mass spectrometry

Measurement of intracellular Ca2+ in cultured rat embryonic hippocampal neurons using a fluorescence microplate reader: potential application to biomolecular screening

Metabolism of propranolol in the human maternal-placental-foetal unit

Morphine has a dual concentration-dependent effect on K(+)-evoked substance P release from rat peripheral airways

Morphine hyposensitivity in streptozotocin-diabetic rats: Reversal by dietary l-arginine treatment

Morphine-3-glucuronide's neuro-excitatory effects are mediated via indirect activation of N-methyl-D-aspartic acid receptors: mechanistic studies in embryonic cultured hippocampal neurones

Morphine-3-glucuronide--a potent antagonist of morphine analgesia

Morphine-3-glucuronide: evidence to support its putative role in the development of tolerance to the antinociceptive effects of morphine in the rat

Multiple sclerosis-induced neuropathic pain: pharmacological management and pathophysiological insights from rodent EAE models

Neurotrophins and Neuropathic Pain: Role in Pathobiology

Nitric oxide modulates μ-opioid receptor function in vitro

Novel Source of Ubiquitous Phthalates as Analytical Contaminant ⬇️

Novel polymeric bioerodable microparticles for prolonged-release intrathecal delivery of analgesic agents for relief of intractable cancer-related pain

Optimization and characterization of a rat model of prostate cancer-induced bone pain using behavioral, pharmacological, radiological, histological and immunohistochemical methods.

Optimization and pharmacological characterization of a refined cisplatin-induced rat model of peripheral neuropathic pain

Oxycodone and morphine have distinctly different pharmacological profiles: radioligand binding and behavioural studies in two rat models of neuropathic pain

Oxycodone has a distinctly different pharmacology from morphine

Oxycodone???s Mechanism of Action and Potency Differences after Spinal and Systemic Routes of Administration

PG545, a dual heparanase and angiogenesis inhibitor, induces potent anti-tumour and anti-metastatic efficacy in preclinical models

Pain, analgesia and genetics ⬇️

Pathobiology and management of prostate cancer-induced bone pain: recent insights and future treatments ⬇️

Pathobiology of cancer chemotherapy-induced peripheral neuropathy (CIPN).

Peripherally acting novel lipo-endomorphin-1 peptides in neuropathic pain without producing constipation