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A bioorthogonal system reveals antitumour immune function of pyroptosis

scientific article published on 11 March 2020

Arginine GlcNAcylation of Rab small GTPases by the pathogen Salmonella Typhimurium

artículo científico publicado en 2020

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

artículo científico publicado en 2015

Cleavage-independent activation of ancient eukaryotic gasdermins and structural mechanisms

artículo científico publicado en 2024

Cullin mediates degradation of RhoA through evolutionarily conserved BTB adaptors to control actin cytoskeleton structure and cell movement

artículo científico publicado en 2009

Glutamine Deamidation and Dysfunction of Ubiquitin/NEDD8 Induced by a Bacterial Effector Family

artículo científico publicado el 5 de agosto de 2010

Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger pyroptosis in target cells

artículo científico publicado en 2020

Growing a gasdermin pore in membranes of pyroptotic cells

artículo científico publicado en 2018

IL-22-induced cell extrusion and IL-18-induced cell death prevent and cure rotavirus infection

scientific article published on 01 October 2020

Improving mass spectrometry analysis of protein structures with arginine-selective chemical cross-linkers

scientific article published on 02 September 2019

Innate immunity to intracellular LPS

artículo científico publicado en 2019

Legionella effector SetA as a general O-glucosyltransferase for eukaryotic proteins

artículo científico publicado en 2019

Metabolic intermediate acetyl phosphate modulates bacterial virulence via acetylation

artículo científico publicado en 2019

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

artículo científico publicado en 2018

N-GSDMD trafficking to neutrophil organelles facilitates IL-1β release independently of plasma membrane pores and pyroptosis

scientific article published on 05 May 2020

Nε-fatty acylation of multiple membrane-associated proteins by Shigella IcsB effector to modulate host function

artículo científico publicado en 2018

Structural mechanism for guanylate-binding proteins (GBPs) targeting by the Shigella E3 ligase IpaH9.8.

artículo científico publicado en 2019

The N-end rule ubiquitin ligase UBR2 mediates NLRP1B inflammasome activation by anthrax lethal toxin

scientific article published on 06 May 2019

The gasdermins, a protein family executing cell death and inflammation

artículo científico publicado en 2019