Lista de obras - Thomas Mertens - Dominio Público Uruguay

A new tool linking human cytomegalovirus drug resistance mutations to resistance phenotypes

artículo científico publicado en 2010

Adoptive transfer and selective reconstitution of streptamer‐selected cytomegalovirus‐specific CD8+ T cells leads to virus clearance in patients after allogeneic peripheral blood stem cell transplantation ⬇️

artículo científico publicado el 6 de diciembre de 2010

Analysis of human cytomegalovirus secondary envelopment by advanced electron microscopy

artículo científico publicado en 2012

Antiviral treatment of cytomegalovirus infection and resistant strains

artículo científico publicado en 2009

Assessment of natural killer cell responses to human cytomegalovirus-infected macrophages

artículo científico publicado en 2013

Beschluss der STIKO zur 1. Aktualisierung der COVID-19-Impfempfehlung und die dazugehörige wissenschaftliche Begründung

artículo científico publicado en 2021

Cellular Immunity and Active Human Cytomegalovirus Infection in Patients with Septic Shock

artículo científico publicado en 2007

Constitutive inositol phosphate formation in cytomegalovirus-infected human fibroblasts is due to expression of the chemokine receptor homologue pUS28.

artículo científico publicado en 2003

Constitutive signaling of the human cytomegalovirus-encoded receptor UL33 differs from that of its rat cytomegalovirus homolog R33 by promiscuous activation of G proteins of the Gq, Gi, and Gs classes.

artículo científico publicado en 2003

Cytomegalovirus primary envelopment at large nuclear membrane infoldings: what's new?

artículo científico publicado en 2007

Cytomegalovirus primary envelopment occurs at large infoldings of the inner nuclear membrane.

artículo científico publicado en 2006

Cytomegalovirus retinitis in a patient treated with anti-tumor necrosis factor alpha antibody therapy for rheumatoid arthritis.

artículo científico publicado en 2004

Development of a high-throughput colorimetric Zika virus infection assay

artículo científico publicado en 2017

Differentiation between Polymorphisms and Resistance-Associated Mutations in Human Cytomegalovirus DNA Polymerase ⬇️

artículo científico publicado el 27 de septiembre de 2010

Early selection of a new UL97 mutant with a severe defect of ganciclovir phosphorylation after valaciclovir prophylaxis and short-term ganciclovir therapy in a renal transplant recipient.

artículo científico publicado en 2005

Fast selection of maribavir resistant cytomegalovirus in a bone marrow transplant recipient

artículo científico publicado en 2013

Fatal reactivation of postnatal cytomegalovirus infection with rapid emergence of ganciclovir resistance in an infant after allogeneic stem cell transplantation

artículo científico publicado en 2005

Fluorescence-based assay for phenotypic characterization of human cytomegalovirus polymerase mutations regarding drug susceptibility and viral replicative fitness

artículo científico publicado en 2009

GCV resistance due to the mutation A594P in the cytomegalovirus protein UL97 is partially reconstituted by a second mutation at D605E.

artículo científico publicado en 2002

Ganciclovir/valganciclovir prophylaxis decreases cytomegalovirus-related events and bronchiolitis obliterans syndrome after lung transplantation.

artículo científico publicado en 2008

HCMV infection of human vascular smooth muscle cells leads to enhanced expression of functionally intact PDGF β-receptor

artículo científico publicado en 2005

HCMV-infection in a human arterial organ culture model: effects on cell proliferation and neointimal hyperplasia

artículo científico publicado en 2007

High variability between results of different in-house tests for cytomegalovirus (CMV) monitoring and a standardized quantitative plasma CMV PCR assay.

artículo científico publicado en 2002

Hintergrundpapier der STIKO: Evaluation der bestehenden Influenzaimpfempfehlung für Indikationsgruppen und für Senioren (Standardimpfung ab 60 Jahren).

artículo científico publicado en 2016

Human Cytomegalovirus pUL47 Modulates Tegumentation and Capsid Accumulation at the Viral Assembly Complex

artículo científico publicado en 2015

Human Macrophages Escape Inhibition of Major Histocompatibility Complex-Dependent Antigen Presentation by Cytomegalovirus and Drive Proliferation and Activation of Memory CD4+ and CD8+ T Cells.

artículo científico publicado en 2018

Human cytomegalovirus infection impairs endothelial cell chemotaxis by disturbing VEGF signalling and actin polymerization

artículo científico publicado en 2014

Human cytomegalovirus infection in human renal arteries in vitro

artículo científico publicado en 2003

Human cytomegalovirus infection of M1 and M2 macrophages triggers inflammation and autologous T-cell proliferation.

artículo científico publicado en 2012

Human cytomegalovirus paralyzes macrophage motility through down-regulation of chemokine receptors, reorganization of the cytoskeleton, and release of macrophage migration inhibitory factor

artículo científico publicado en 2009

Human cytomegalovirus tegument protein ppUL35 is important for viral replication and particle formation

artículo científico publicado en 2005

Human cytomegalovirus-induced NKG2C(hi) CD57(hi) natural killer cells are effectors dependent on humoral antiviral immunity

artículo científico publicado en 2013

Human cytomegalovirus-induced reduction of extracellular matrix proteins in vascular smooth muscle cell cultures: a pathomechanism in vasculopathies?

artículo científico publicado en 2006

Identification of the first nonpeptidergic inverse agonist for a constitutively active viral-encoded G protein-coupled receptor

artículo científico publicado en 2002

Impfen bei Immundefizienz : Anwendungshinweise zu den von der Ständigen Impfkommission empfohlenen Impfungen(I) Grundlagenpapier.

artículo científico publicado en 2017

Improved detection of mutated human cytomegalovirus UL97 by pyrosequencing

artículo científico publicado en 2010

In vivo/ex vivo T cell depletion for GVHD prophylaxis influences onset and course of active cytomegalovirus infection and disease after BMT

artículo científico publicado el 1 de marzo de 1995

Inactivation and Environmental Stability of Zika Virus

artículo científico publicado en 2016

Influenza vaccination and the end of simplicity

artículo científico publicado en 2013

Interleukin-2 from Adaptive T Cells Enhances Natural Killer Cell Activity against Human Cytomegalovirus-Infected Macrophages

artículo científico publicado en 2015

Late HBsAg seroreversion of mutated hepatitis B virus after bone marrow transplantation

artículo científico publicado en 2013

Major tegument protein pp65 of human cytomegalovirus is required for the incorporation of pUL69 and pUL97 into the virus particle and for viral growth in macrophages

scientific article published on 30 December 2008

Megapinocytosis: a novel endocytic pathway

artículo científico publicado en 2016

Multimer staining of cytomegalovirus phosphoprotein 65-specific T cells for diagnosis and therapeutic purposes: a comparative study

scientific article published on 01 May 2008

Mutations in the UL97 ORF of ganciclovir-resistant clinical cytomegalovirus isolates differentially affect GCV phosphorylation as determined in a recombinant vaccinia virus system

artículo científico publicado en 2002

NK Cells from RAG- or DCLRE1C-Deficient Patients Inhibit HCMV

scientific article published on 10 November 2019

Natural killer cells can inhibit the transmission of human cytomegalovirus in cell culture by using mechanisms from innate and adaptive immune responses

artículo científico publicado en 2014

Naïve T cells are activated by autologous HCMV-infected endothelial cells through NKG2D and can control HCMV transmission in vitro.

artículo científico publicado en 2017

Nuclear targeting of human cytomegalovirus large tegument protein pUL48 is essential for viral growth

artículo científico publicado en 2013

Peptide vaccination in the presence of adjuvants in patients after hematopoietic stem cell transplantation with CD4+ T cell reconstitution elicits consistent CD8+ T cell responses

artículo científico publicado en 2017

Post-pandemic seroprevalence of pandemic influenza A (H1N1) 2009 infection (swine flu) among children <18 years in Germany

artículo científico publicado en 2011

Protein pUL128 of Human Cytomegalovirus Is Necessary for Monocyte Infection and Blocking of Migration ⬇️

artículo científico publicado el 2 de marzo de 2011

Quantitative investigation of murine cytomegalovirus nucleocapsid interaction

artículo científico publicado en 2007

Report on the 1st international workshop on procedures for the development of evidence-based vaccination recommendations, Berlin, Germany, 22-23 November 2010.

artículo científico publicado en 2011

Role of the human herpesvirus 6 u69-encoded kinase in the phosphorylation of ganciclovir

artículo científico publicado en 2002

Single nucleotide polymorphisms of thymidine kinase and DNA polymerase genes in clinical herpes simplex virus type 1 isolates associated with different resistance phenotypes.

artículo científico publicado en 2014

The 7-transmembrane protein homologue UL78 of the human cytomegalovirus forms oligomers and traffics between the plasma membrane and different intracellular compartments ⬇️

artículo científico publicado el 12 de febrero de 2012

The Tegument Protein UL71 of Human Cytomegalovirus Is Involved in Late Envelopment and Affects Multivesicular Bodies ⬇️

artículo científico publicado el 2 de febrero de 2011

The UL97 protein kinase of human cytomegalovirus and homologues in other herpesviruses: impact on virus and host.

artículo científico publicado en 2004

The human cytomegalovirus UL78 gene is highly conserved among clinical isolates, but is dispensable for replication in fibroblasts and a renal artery organ-culture system

artículo científico publicado en 2005

The immunodominant CD8 T cell response to the human cytomegalovirus tegument phosphoprotein pp65(495-503) epitope critically depends on CD4 T cell help in vaccinated HLA-A*0201 transgenic mice

artículo científico publicado en 2011

Upregulation of functionally active vascular endothelial growth factor by human cytomegalovirus

artículo científico publicado en 2005

Varicella-zoster-virus vaccination in immunosuppressed children with rheumatic diseases using a pre-vaccination check list.

artículo científico publicado en 2018

[Vaccination in Germany - Recommendations of STIKO]

artículo científico publicado en 2019

Lista de obras de Thomas Mertens

A new tool linking human cytomegalovirus drug resistance mutations to resistance phenotypes

Adoptive transfer and selective reconstitution of streptamer‐selected cytomegalovirus‐specific CD8+ T cells leads to virus clearance in patients after allogeneic peripheral blood stem cell transplantation ⬇️

Analysis of human cytomegalovirus secondary envelopment by advanced electron microscopy

Antiviral treatment of cytomegalovirus infection and resistant strains

Assessment of natural killer cell responses to human cytomegalovirus-infected macrophages

Beschluss der STIKO zur 1. Aktualisierung der COVID-19-Impfempfehlung und die dazugehörige wissenschaftliche Begründung

Cellular Immunity and Active Human Cytomegalovirus Infection in Patients with Septic Shock

Constitutive inositol phosphate formation in cytomegalovirus-infected human fibroblasts is due to expression of the chemokine receptor homologue pUS28.

Constitutive signaling of the human cytomegalovirus-encoded receptor UL33 differs from that of its rat cytomegalovirus homolog R33 by promiscuous activation of G proteins of the Gq, Gi, and Gs classes.

Cytomegalovirus primary envelopment at large nuclear membrane infoldings: what's new?

Cytomegalovirus primary envelopment occurs at large infoldings of the inner nuclear membrane.

Cytomegalovirus retinitis in a patient treated with anti-tumor necrosis factor alpha antibody therapy for rheumatoid arthritis.

Development of a high-throughput colorimetric Zika virus infection assay

Differentiation between Polymorphisms and Resistance-Associated Mutations in Human Cytomegalovirus DNA Polymerase ⬇️

Early selection of a new UL97 mutant with a severe defect of ganciclovir phosphorylation after valaciclovir prophylaxis and short-term ganciclovir therapy in a renal transplant recipient.

Fast selection of maribavir resistant cytomegalovirus in a bone marrow transplant recipient

Fatal reactivation of postnatal cytomegalovirus infection with rapid emergence of ganciclovir resistance in an infant after allogeneic stem cell transplantation

Fluorescence-based assay for phenotypic characterization of human cytomegalovirus polymerase mutations regarding drug susceptibility and viral replicative fitness

GCV resistance due to the mutation A594P in the cytomegalovirus protein UL97 is partially reconstituted by a second mutation at D605E.

Ganciclovir/valganciclovir prophylaxis decreases cytomegalovirus-related events and bronchiolitis obliterans syndrome after lung transplantation.

HCMV infection of human vascular smooth muscle cells leads to enhanced expression of functionally intact PDGF β-receptor

HCMV-infection in a human arterial organ culture model: effects on cell proliferation and neointimal hyperplasia

High variability between results of different in-house tests for cytomegalovirus (CMV) monitoring and a standardized quantitative plasma CMV PCR assay.

Hintergrundpapier der STIKO: Evaluation der bestehenden Influenzaimpfempfehlung für Indikationsgruppen und für Senioren (Standardimpfung ab 60 Jahren).

Human Cytomegalovirus pUL47 Modulates Tegumentation and Capsid Accumulation at the Viral Assembly Complex

Human Macrophages Escape Inhibition of Major Histocompatibility Complex-Dependent Antigen Presentation by Cytomegalovirus and Drive Proliferation and Activation of Memory CD4+ and CD8+ T Cells.

Human cytomegalovirus infection impairs endothelial cell chemotaxis by disturbing VEGF signalling and actin polymerization

Human cytomegalovirus infection in human renal arteries in vitro

Human cytomegalovirus infection of M1 and M2 macrophages triggers inflammation and autologous T-cell proliferation.

Human cytomegalovirus paralyzes macrophage motility through down-regulation of chemokine receptors, reorganization of the cytoskeleton, and release of macrophage migration inhibitory factor

Human cytomegalovirus tegument protein ppUL35 is important for viral replication and particle formation

Human cytomegalovirus-induced NKG2C(hi) CD57(hi) natural killer cells are effectors dependent on humoral antiviral immunity

Human cytomegalovirus-induced reduction of extracellular matrix proteins in vascular smooth muscle cell cultures: a pathomechanism in vasculopathies?

Identification of the first nonpeptidergic inverse agonist for a constitutively active viral-encoded G protein-coupled receptor

Impfen bei Immundefizienz : Anwendungshinweise zu den von der Ständigen Impfkommission empfohlenen Impfungen(I) Grundlagenpapier.

Improved detection of mutated human cytomegalovirus UL97 by pyrosequencing

In vivo/ex vivo T cell depletion for GVHD prophylaxis influences onset and course of active cytomegalovirus infection and disease after BMT

Inactivation and Environmental Stability of Zika Virus

Influenza vaccination and the end of simplicity

Interleukin-2 from Adaptive T Cells Enhances Natural Killer Cell Activity against Human Cytomegalovirus-Infected Macrophages

Late HBsAg seroreversion of mutated hepatitis B virus after bone marrow transplantation

Major tegument protein pp65 of human cytomegalovirus is required for the incorporation of pUL69 and pUL97 into the virus particle and for viral growth in macrophages

Megapinocytosis: a novel endocytic pathway

Multimer staining of cytomegalovirus phosphoprotein 65-specific T cells for diagnosis and therapeutic purposes: a comparative study

Mutations in the UL97 ORF of ganciclovir-resistant clinical cytomegalovirus isolates differentially affect GCV phosphorylation as determined in a recombinant vaccinia virus system

NK Cells from RAG- or DCLRE1C-Deficient Patients Inhibit HCMV

Natural killer cells can inhibit the transmission of human cytomegalovirus in cell culture by using mechanisms from innate and adaptive immune responses

Naïve T cells are activated by autologous HCMV-infected endothelial cells through NKG2D and can control HCMV transmission in vitro.

Nuclear targeting of human cytomegalovirus large tegument protein pUL48 is essential for viral growth

Peptide vaccination in the presence of adjuvants in patients after hematopoietic stem cell transplantation with CD4+ T cell reconstitution elicits consistent CD8+ T cell responses

Post-pandemic seroprevalence of pandemic influenza A (H1N1) 2009 infection (swine flu) among children <18 years in Germany

Protein pUL128 of Human Cytomegalovirus Is Necessary for Monocyte Infection and Blocking of Migration ⬇️

Quantitative investigation of murine cytomegalovirus nucleocapsid interaction

Report on the 1st international workshop on procedures for the development of evidence-based vaccination recommendations, Berlin, Germany, 22-23 November 2010.

Role of the human herpesvirus 6 u69-encoded kinase in the phosphorylation of ganciclovir

Single nucleotide polymorphisms of thymidine kinase and DNA polymerase genes in clinical herpes simplex virus type 1 isolates associated with different resistance phenotypes.

The 7-transmembrane protein homologue UL78 of the human cytomegalovirus forms oligomers and traffics between the plasma membrane and different intracellular compartments ⬇️

The Tegument Protein UL71 of Human Cytomegalovirus Is Involved in Late Envelopment and Affects Multivesicular Bodies ⬇️

The UL97 protein kinase of human cytomegalovirus and homologues in other herpesviruses: impact on virus and host.

The human cytomegalovirus UL78 gene is highly conserved among clinical isolates, but is dispensable for replication in fibroblasts and a renal artery organ-culture system

The immunodominant CD8 T cell response to the human cytomegalovirus tegument phosphoprotein pp65(495-503) epitope critically depends on CD4 T cell help in vaccinated HLA-A*0201 transgenic mice

Upregulation of functionally active vascular endothelial growth factor by human cytomegalovirus

Varicella-zoster-virus vaccination in immunosuppressed children with rheumatic diseases using a pre-vaccination check list.

[Vaccination in Germany - Recommendations of STIKO]