Lista de obras - Adi Kimchi - Dominio Público Uruguay

A cancer associated somatic mutation in LC3B attenuates its binding to E1-like ATG7 protein and subsequent lipidation

artículo científico publicado en 2018

A high throughput proteomics screen identifies novel substrates of death-associated protein kinase

artículo científico publicado en 2008

A new function for the serine protease HtrA2 in controlling radiation-induced senescence in cancer cells

artículo científico publicado en 2022

A short mitochondrial form of p19ARF induces autophagy and caspase-independent cell death

artículo científico publicado en 2006

A smARF way to die: a novel short isoform of p19ARF is linked to autophagic cell death

artículo científico publicado en 2006

AMPK activates DAPK2 to promote autophagy

ANAT: a tool for constructing and analyzing functional protein networks

artículo científico publicado en 2011

Antisense Libraries to Isolate Tumor Suppressor Genes

artículo científico publicado el 1 de enero de 2003

Assignment of Death Associated Protein 3 (DAP3) to human chromosome 1q21 by in situ hybridization ⬇️

artículo científico publicado el 1 de enero de 1997

Autophagy and cell death.

artículo científico publicado en 2007

Autophagy and tumor suppression: recent advances in understanding the link between autophagic cell death pathways and tumor development

scientific article published on January 2008

Autophagy as a cell death and tumor suppressor mechanism

artículo científico publicado en 2004

Autophagy gets a brake: DAP1, a novel mTOR substrate, is activated to suppress the autophagic process

artículo científico publicado en 2010

Autophagy, Inflammation, and Metabolism (AIM) Center in its second year

scientific article published on 15 July 2019

Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence: supporting the next generation of autophagy researchers and fostering international collaborations

artículo científico publicado en 2018

Autophagy-dependent cell death - where, how and why a cell eats itself to death

scientific article published on 20 September 2018

Biochemical and functional characterization of the ROC domain of DAPK establishes a new paradigm of GTP regulation in ROCO proteins

artículo científico publicado en 2012

Cap-independent translation by DAP5 controls cell fate decisions in human embryonic stem cells

artículo científico publicado en 2016

Cell biology. Promoting tumorigenesis by suppressing autophagy.

artículo científico publicado en 2012

Changes in cIAP2, survivin and BimEL expression characterize the switch from autophagy to apoptosis in prolonged starvation.

artículo científico publicado en 2017

DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death

artículo científico publicado en 2002

DAP-kinase and autophagy

artículo científico

DAP-kinase as a target for drug design in cancer and diseases associated with accelerated cell death

artículo científico publicado en 2004

DAP-kinase loss of expression in various carcinoma and B-cell lymphoma cell lines: possible implications for role as tumor suppressor gene ⬇️

artículo científico publicado el 24 de julio de 1997

DAP1, a novel substrate of mTOR, negatively regulates autophagy

artículo científico publicado en 2010

DAP5 associates with eIF2β and eIF4AI to promote Internal Ribosome Entry Site driven translation

artículo científico publicado en 2015

DAP5 promotes cap-independent translation of Bcl-2 and CDK1 to facilitate cell survival during mitosis

artículo científico publicado en 2008

DAPK activates MARK1/2 to regulate microtubule assembly, neuronal differentiation, and tau toxicity ⬇️

artículo científico publicado el 11 de febrero de 2011

DAPk and pyruvate kinase: unlikely partners in cancer metabolic regulation.

artículo científico publicado en 2012

DAPk protein family and cancer

artículo científico publicado en 2006

DAPk silencing by DNA methylation conveys resistance to anti EGFR drugs in lung cancer cells.

artículo científico publicado en 2012

Death by over-eating: The Gaucher disease associated gene GBA1, identified in a screen for mediators of autophagic cell death, is necessary for developmental cell death in Drosophila midgut.

artículo científico publicado en 2017

Death-associated protein (DAP) kinase plays a central role in ceramide-induced apoptosis in cultured hippocampal neurons

artículo científico publicado en 2001

Death-associated protein 3 localizes to the mitochondria and is involved in the process of mitochondrial fragmentation during cell death

artículo científico publicado en 2004

Death-associated protein kinase loss of expression is a new marker for breast cancer prognosis

artículo científico publicado en 2004

Death-associated protein kinase phosphorylates ZIP kinase, forming a unique kinase hierarchy to activate its cell death functions.

artículo científico publicado en 2004

Discovering protein-protein interactions within the programmed cell death network using a protein-fragment complementation screen

artículo científico publicado en 2014

ETS Proteins Bind with Glucocorticoid Receptors: Relevance for Treatment of Ewing Sarcoma

scientific article published on 01 October 2019

GTP binding to the ROC domain of DAP-kinase regulates its function through intramolecular signalling

artículo científico publicado en 2011

Guidelines for the use and interpretation of assays for monitoring autophagy

artículo científico publicado en 2012

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

artículo científico publicado en 2008

Hsp90 Recognizes a Common Surface on Client Kinases

artículo científico publicado en 2006

Immune-related mechanisms participating in resistance and susceptibility to glutamate toxicity

artículo científico publicado en 2002

Initial Characterization of a Spontaneous Interferon Secreted During Growth and Differentiation of Friend Erythroleukemia Cells ⬇️

artículo científico publicado el 1 de diciembre de 1982

Interferons and Interleukin-6 Suppress the DNA-Binding Activity of E2F in Growth-Sensitive Hematopoietic Cells ⬇️

artículo científico publicado el 1 de septiembre de 1993

Lethal weapons: DAP-kinase, autophagy and cell death: DAP-kinase regulates autophagy

scientific article published on 11 December 2009

Life in the balance - a mechanistic view of the crosstalk between autophagy and apoptosis

artículo científico publicado en 2012

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

artículo científico publicado en 2018

Myosin drives autophagy in a pathway linking Atg1 to Atg9.

artículo científico publicado en 2011

New modularity of DAP-kinases: alternative splicing of the DRP-1 gene produces a ZIPk-like isoform

artículo científico publicado en 2011

Non-canonical activation of DAPK2 by AMPK constitutes a new pathway linking metabolic stress to autophagy.

artículo científico publicado en 2018

Nucleolar p19ARF, unlike mitochondrial smARF, is incapable of inducing p53-independent autophagy

artículo científico publicado en 2008

PKD at the crossroads of necrosis and autophagy

artículo científico publicado en 2012

PKD is a kinase of Vps34 that mediates ROS-induced autophagy downstream of DAPk ⬇️

artículo científico publicado el 18 de noviembre de 2011

Phosphorylation of Beclin 1 by DAP-kinase promotes autophagy by weakening its interactions with Bcl-2 and Bcl-XL.

artículo científico publicado en 2009

Pin-pointing a new DAP kinase function: the peptidyl-proly isomerase Pin1 Is Negatively Regulated by DAP kinase-mediated phosphorylation

artículo científico publicado en 2011

Programmed cell death: from novel gene discovery to studies on network connectivity and emerging biomedical implications

artículo científico publicado en 2007

Progress in differentiation induction as a treatment for acute promyelocytic leukemia and beyond

artículo científico publicado en 2002

SPIKE: a database of highly curated human signaling pathways

artículo científico publicado en 2011

Ser289 phosphorylation activates both DAPK1 and DAPK2 but in response to different intracellular signaling pathways

artículo científico publicado en 2019

Signalome-wide RNAi screen identifies GBA1 as a positive mediator of autophagic cell death

artículo científico publicado en 2017

Systems biology analysis of programmed cell death

scientific article published on 28 May 2010

The DAP-kinase family of proteins: study of a novel group of calcium-regulated death-promoting kinases

artículo científico publicado en 2002

The DAP-kinase interactome

artículo científico

The DAPK family: a structure-function analysis

artículo científico

The autophagy protein Atg12 associates with antiapoptotic Bcl-2 family members to promote mitochondrial apoptosis

artículo científico publicado en 2011

The caspase-cleaved DAP5 protein supports internal ribosome entry site-mediated translation of death proteins

artículo científico publicado en 2002

The crystal structure of the C-terminal DAP5/p97 domain sheds light on the molecular basis for its processing by caspase cleavage

artículo científico publicado en 2008

The death-associated protein kinases: structure, function, and beyond

artículo científico publicado en 2006

The dependence receptor UNC5H2 mediates apoptosis through DAP-kinase

artículo científico publicado en 2005

The dependence receptor UNC5H2/B triggers apoptosis via PP2A-mediated dephosphorylation of DAP kinase

artículo científico publicado en 2010

The paradox of autophagy and its implication in cancer etiology and therapy

artículo científico publicado en 2009

The programmed cell death GLuc PCA library - a powerful tool for pathway discovery and drug screening

artículo científico publicado en 2014

The regulation of death-associated protein (DAP) kinase in apoptosis.

artículo científico publicado en 2002

The road not taken: a systems level strategy for analyzing the cell death network

artículo científico publicado en 2010

The translation initiation factor DAP5 is a regulator of cell survival during mitosis

scientific article published on 10 January 2009

Toward accurate reconstruction of functional protein networks

artículo científico publicado en 2009

Tumor suppressor death-associated protein kinase 1 inhibits necroptosis by p38 MAPK activation

scientific article published on 04 May 2020

Tumor suppressor death-associated protein kinase attenuates inflammatory responses in the lung

scientific article published on 13 October 2011

Tumor suppressor death-associated protein kinase is required for full IL-1β production.

artículo científico publicado en 2010

Tumour suppressor death-associated protein kinase targets cytoplasmic HIF-1α for Th17 suppression

artículo científico publicado en 2016

ZIPK: a unique case of murine-specific divergence of a conserved vertebrate gene

artículo científico publicado en 2007

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

artículo científico publicado en 2016

Lista de obras de Adi Kimchi

A cancer associated somatic mutation in LC3B attenuates its binding to E1-like ATG7 protein and subsequent lipidation

A high throughput proteomics screen identifies novel substrates of death-associated protein kinase

A new function for the serine protease HtrA2 in controlling radiation-induced senescence in cancer cells

A short mitochondrial form of p19ARF induces autophagy and caspase-independent cell death

A smARF way to die: a novel short isoform of p19ARF is linked to autophagic cell death

AMPK activates DAPK2 to promote autophagy

ANAT: a tool for constructing and analyzing functional protein networks

Antisense Libraries to Isolate Tumor Suppressor Genes

Assignment of Death Associated Protein 3 (DAP3) to human chromosome 1q21 by in situ hybridization ⬇️

Autophagy and cell death.

Autophagy and tumor suppression: recent advances in understanding the link between autophagic cell death pathways and tumor development

Autophagy as a cell death and tumor suppressor mechanism

Autophagy gets a brake: DAP1, a novel mTOR substrate, is activated to suppress the autophagic process

Autophagy, Inflammation, and Metabolism (AIM) Center in its second year

Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence: supporting the next generation of autophagy researchers and fostering international collaborations

Autophagy-dependent cell death - where, how and why a cell eats itself to death

Biochemical and functional characterization of the ROC domain of DAPK establishes a new paradigm of GTP regulation in ROCO proteins

Cap-independent translation by DAP5 controls cell fate decisions in human embryonic stem cells

Cell biology. Promoting tumorigenesis by suppressing autophagy.

Changes in cIAP2, survivin and BimEL expression characterize the switch from autophagy to apoptosis in prolonged starvation.

DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death

DAP-kinase and autophagy

DAP-kinase as a target for drug design in cancer and diseases associated with accelerated cell death

DAP-kinase loss of expression in various carcinoma and B-cell lymphoma cell lines: possible implications for role as tumor suppressor gene ⬇️

DAP1, a novel substrate of mTOR, negatively regulates autophagy

DAP5 associates with eIF2β and eIF4AI to promote Internal Ribosome Entry Site driven translation

DAP5 promotes cap-independent translation of Bcl-2 and CDK1 to facilitate cell survival during mitosis

DAPK activates MARK1/2 to regulate microtubule assembly, neuronal differentiation, and tau toxicity ⬇️

DAPk and pyruvate kinase: unlikely partners in cancer metabolic regulation.

DAPk protein family and cancer

DAPk silencing by DNA methylation conveys resistance to anti EGFR drugs in lung cancer cells.

Death by over-eating: The Gaucher disease associated gene GBA1, identified in a screen for mediators of autophagic cell death, is necessary for developmental cell death in Drosophila midgut.

Death-associated protein (DAP) kinase plays a central role in ceramide-induced apoptosis in cultured hippocampal neurons

Death-associated protein 3 localizes to the mitochondria and is involved in the process of mitochondrial fragmentation during cell death

Death-associated protein kinase loss of expression is a new marker for breast cancer prognosis

Death-associated protein kinase phosphorylates ZIP kinase, forming a unique kinase hierarchy to activate its cell death functions.

Discovering protein-protein interactions within the programmed cell death network using a protein-fragment complementation screen

ETS Proteins Bind with Glucocorticoid Receptors: Relevance for Treatment of Ewing Sarcoma

GTP binding to the ROC domain of DAP-kinase regulates its function through intramolecular signalling

Guidelines for the use and interpretation of assays for monitoring autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

Hsp90 Recognizes a Common Surface on Client Kinases

Immune-related mechanisms participating in resistance and susceptibility to glutamate toxicity

Initial Characterization of a Spontaneous Interferon Secreted During Growth and Differentiation of Friend Erythroleukemia Cells ⬇️

Interferons and Interleukin-6 Suppress the DNA-Binding Activity of E2F in Growth-Sensitive Hematopoietic Cells ⬇️

Lethal weapons: DAP-kinase, autophagy and cell death: DAP-kinase regulates autophagy

Life in the balance - a mechanistic view of the crosstalk between autophagy and apoptosis

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Myosin drives autophagy in a pathway linking Atg1 to Atg9.

New modularity of DAP-kinases: alternative splicing of the DRP-1 gene produces a ZIPk-like isoform

Non-canonical activation of DAPK2 by AMPK constitutes a new pathway linking metabolic stress to autophagy.

Nucleolar p19ARF, unlike mitochondrial smARF, is incapable of inducing p53-independent autophagy

PKD at the crossroads of necrosis and autophagy

PKD is a kinase of Vps34 that mediates ROS-induced autophagy downstream of DAPk ⬇️

Phosphorylation of Beclin 1 by DAP-kinase promotes autophagy by weakening its interactions with Bcl-2 and Bcl-XL.

Pin-pointing a new DAP kinase function: the peptidyl-proly isomerase Pin1 Is Negatively Regulated by DAP kinase-mediated phosphorylation

Programmed cell death: from novel gene discovery to studies on network connectivity and emerging biomedical implications

Progress in differentiation induction as a treatment for acute promyelocytic leukemia and beyond

SPIKE: a database of highly curated human signaling pathways

Ser289 phosphorylation activates both DAPK1 and DAPK2 but in response to different intracellular signaling pathways

Signalome-wide RNAi screen identifies GBA1 as a positive mediator of autophagic cell death

Systems biology analysis of programmed cell death

The DAP-kinase family of proteins: study of a novel group of calcium-regulated death-promoting kinases

The DAP-kinase interactome

The DAPK family: a structure-function analysis

The autophagy protein Atg12 associates with antiapoptotic Bcl-2 family members to promote mitochondrial apoptosis

The caspase-cleaved DAP5 protein supports internal ribosome entry site-mediated translation of death proteins

The crystal structure of the C-terminal DAP5/p97 domain sheds light on the molecular basis for its processing by caspase cleavage

The death-associated protein kinases: structure, function, and beyond

The dependence receptor UNC5H2 mediates apoptosis through DAP-kinase

The dependence receptor UNC5H2/B triggers apoptosis via PP2A-mediated dephosphorylation of DAP kinase

The paradox of autophagy and its implication in cancer etiology and therapy

The programmed cell death GLuc PCA library - a powerful tool for pathway discovery and drug screening

The regulation of death-associated protein (DAP) kinase in apoptosis.

The road not taken: a systems level strategy for analyzing the cell death network

The translation initiation factor DAP5 is a regulator of cell survival during mitosis

Toward accurate reconstruction of functional protein networks

Tumor suppressor death-associated protein kinase 1 inhibits necroptosis by p38 MAPK activation

Tumor suppressor death-associated protein kinase attenuates inflammatory responses in the lung