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Lista de obras de Craig M. Crews

Addressing Kinase-Independent Functions of Fak via PROTAC-Mediated Degradation

artículo científico publicado en 2018

Androgen receptor degradation by the proteolysis-targeting chimera ARCC-4 outperforms enzalutamide in cellular models of prostate cancer drug resistance

artículo científico publicado en 2018

Assessing Different E3 Ligases for Small Molecule Induced Protein Ubiquitination and Degradation.

artículo científico publicado en 2017

Catalytic in vivo protein knockdown by small-molecule PROTACs.

artículo científico publicado en 2015

Differential PROTAC substrate specificity dictated by orientation of recruited E3 ligase

artículo científico publicado en 2019

Enhancing Antiproliferative Activity and Selectivity of a FLT-3 Inhibitor by Proteolysis Targeting Chimera Conversion

artículo científico publicado en 2018

Evolving Rules for Protein Degradation? Insights from the Zinc Finger Degrome

scientific article published on 25 January 2019

Identification and Characterization of Von Hippel-Lindau-Recruiting Proteolysis Targeting Chimeras (PROTACs) of TANK-Binding Kinase 1.

artículo científico publicado en 2017

Inducing Protein Degradation as a Therapeutic Strategy

artículo científico publicado en 2017

Lineage tracing of genome-edited alleles reveals high fidelity axolotl limb regeneration

artículo científico publicado en 2017

MDM2-recruiting PROTAC Offers Superior, Synergistic Anti-proliferative Activity via Simultaneous Degradation of BRD4 and Stabilization of p53

scientific article published on 01 November 2018

Multiplex CRISPR/Cas screen in regenerating haploid limbs of chimeric Axolotls

artículo científico publicado en 2020

Pharmacological targeting of the pseudokinase Her3

artículo científico publicado en 2014

Protein targeting chimeric molecules specific for bromodomain and extra-terminal motif family proteins are active against pre-clinical models of multiple myeloma

artículo científico publicado en 2018

Proteolysis-Targeting Chimeras: Induced Protein Degradation as a Therapeutic Strategy.

artículo científico publicado en 2017

RUNX1-targeted therapy for AML expressing somatic or germline mutation in RUNX1

scientific article published on 25 April 2019

Small-Molecule Modulation of Protein Homeostasis.

artículo científico publicado en 2017

Targeted protein degradation: expanding the toolbox

scientific article published on 30 October 2019

Targeted protein destabilization reveals an estrogen-mediated ER stress response

artículo científico publicado en 2014

Targeting BCR-ABL1 in Chronic Myeloid Leukemia by PROTAC-Mediated Targeted Protein Degradation

scientific article published on 16 July 2019

Targeting nuclear β-catenin as therapy for post-myeloproliferative neoplasm secondary AML

artículo científico publicado en 2018

Waste disposal-An attractive strategy for cancer therapy.

artículo científico publicado en 2017

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