Lista de obras - Charles Antzelevitch - Dominio Público Uruguay

A CACNA1C variant associated with reduced voltage-dependent inactivation, increased CaV1.2 channel window current, and arrhythmogenesis

artículo científico publicado en 2014

A common single nucleotide polymorphism can exacerbate long-QT type 2 syndrome leading to sudden infant death.

artículo científico publicado en 2010

A complete right bundle-branch block masking Brugada syndrome

artículo científico publicado en 2012

A gain-of-function I(K-ATP) mutation and its role in sudden cardiac death associated with J-wave syndromes

artículo científico publicado en 2010

A molecular link between the sudden infant death syndrome and the long-QT syndrome

artículo científico publicado en 2000

A mutation in the beta 3 subunit of the cardiac sodium channel associated with Brugada ECG phenotype

artículo científico publicado en 2009

A novel mutation in KCNQ1 associated with a potent dominant negative effect as the basis for the LQT1 form of the long QT syndrome.

artículo científico publicado en 2007

A novel mutation in the HCN4 gene causes symptomatic sinus bradycardia in Moroccan Jews.

artículo científico publicado en 2010

A novel rare variant in SCN1Bb linked to Brugada syndrome and SIDS by combined modulation of Na(v)1.5 and K(v)4.3 channel currents

artículo científico publicado en 2011

A temporal window of vulnerability for development of atrial fibrillation with advancing heart failure

article

A transient outward potassium current activator recapitulates the electrocardiographic manifestations of Brugada syndrome.

artículo científico publicado en 2008

ABCC9 is a novel Brugada and early repolarization syndrome susceptibility gene.

artículo científico publicado en 2014

ABSTRACTS

scholarly article

AZD1305 exerts atrial predominant electrophysiological actions and is effective in suppressing atrial fibrillation and preventing its reinduction in the dog

artículo científico publicado en 2010

Abnormal repolarization as the basis for late potentials and fractionated electrograms recorded from epicardium in experimental models of Brugada syndrome

artículo científico publicado en 2014

Accelerated inactivation of the L-type calcium current due to a mutation in CACNB2b underlies Brugada syndrome

artículo científico publicado en 2009

Acute dronedarone is inferior to amiodarone in terminating and preventing atrial fibrillation in canine atria.

artículo científico publicado en 2010

Acute myocardial ischemia: cellular mechanisms underlying ST segment elevation

artículo científico

Advances in the Pharmacologic Management of Atrial Fibrillation

artículo científico publicado en 2011

Advances in the Pharmacological Treatment of Atrial Fibrillation ⬇️

artículo científico publicado el 1 de enero de 2010

Ajmaline-Induced Slowing of Conduction in the Right Ventricular Outflow Tract Cannot Account for ST Elevation in Patients With Type I Brugada ECG.

artículo científico publicado en 2017

American Heart Association atrial fibrillation research summit: a conference report from the American Heart Association

artículo científico publicado en 2011

Amplified transmural dispersion of repolarization as the basis for arrhythmogenesis in a canine ventricular-wedge model of short-QT syndrome

artículo científico publicado en 2004

An international compendium of mutations in the SCN5A-encoded cardiac sodium channel in patients referred for Brugada syndrome genetic testing

artículo científico publicado en 2009

Andersen-Tawil syndrome: Clinical presentation and predictors of symptomatic arrhythmias - Possible role of polymorphisms K897T in KCNH2 and H558R in SCN5A gene

artículo científico publicado en 2017

Androgens and male predominance of the Brugada syndrome phenotype

artículo científico publicado en 2003

Antiarrhythmic effects of losartan and enalapril in canine pulmonary vein sleeve preparations.

artículo científico publicado en 2010

Antiarrhythmic effects of ranolazine in a guinea pig in vitro model of long-QT syndrome

artículo científico publicado en 2004

Antiarrhythmic effects of ranolazine in canine pulmonary vein sleeve preparations.

artículo científico publicado en 2008

Antiarrhythmic effects of simvastatin in canine pulmonary vein sleeve preparations

artículo científico publicado en 2011

Antiarrhythmic effects of the highly selective late sodium channel current blocker GS-458967

scientific article published on 22 March 2013

Arrhythmogenic mechanisms of QT prolonging drugs: is QT prolongation really the problem?

artículo científico publicado en 2004

Assessing predictors of drug-induced torsade de pointes.

artículo científico publicado en 2003

Atria are More Sensitive Than Ventricles to GS-458967-Induced Inhibition of Late Sodium Current

artículo científico publicado en 2015

Atrial fibrillation and Brugada syndrome

artículo científico publicado en 2008

Atrial fibrillation in inherited cardiac channelopathies: From mechanisms to management

artículo científico publicado en 2016

Atrial-selective effects of chronic amiodarone in the management of atrial fibrillation.

artículo científico publicado en 2008

Atrial-selective inhibition of sodium-channel current by Wenxin Keli is effective in suppressing atrial fibrillation.

artículo científico publicado en 2011

Atrial-selective prolongation of refractory period with AVE0118 is due principally to inhibition of sodium channel activity

artículo científico publicado en 2012

Atrial-selective sodium channel block as a novel strategy for the management of atrial fibrillation

artículo científico publicado en 2009

Atrial-selective sodium channel block as a novel strategy for the management of atrial fibrillation.

artículo científico publicado en 2010

Atrial-selective sodium channel block as a strategy for suppression of atrial fibrillation

artículo científico publicado en 2008

Atrial-selective sodium channel block for the treatment of atrial fibrillation.

artículo científico publicado en 2009

Atrial-selective sodium channel block strategy to suppress atrial fibrillation: ranolazine versus propafenone.

artículo científico publicado en 2011

Atrial-selective sodium channel blockers: do they exist?

artículo científico publicado en 2008

Atrium-selective sodium channel block as a strategy for suppression of atrial fibrillation: differences in sodium channel inactivation between atria and ventricles and the role of ranolazine

artículo científico publicado en 2007

Augmentation of J waves and electrical storms in patients with early repolarization

artículo científico publicado en 2008

Augmentation of late sodium current unmasks the proarrhythmic effects of amiodarone.

artículo científico publicado en 2007

Author's response to letter to the editor from Perez and Froelicher.

artículo científico publicado en 2013

Autonomic aspects of arrhythmogenesis: the enduring and the new.

artículo científico publicado en 2004

Basic mechanisms of reentrant arrhythmias

artículo científico publicado en 2001

Biophysical and molecular characterization of a novel de novo KCNJ2 mutation associated with Andersen-Tawil syndrome and catecholaminergic polymorphic ventricular tachycardia mimicry

artículo científico publicado en 2010

Blinded validation of the isolated arterially perfused rabbit ventricular wedge in preclinical assessment of drug-induced proarrhythmias.

artículo científico publicado en 2006

Brugada Syndrome: Cellular Mechanisms and Approaches to Therapy

scientific article

Brugada Syndrome: Clinical, Genetic, Molecular, Cellular, and Ionic Aspects

artículo científico publicado en 2015

Brugada Syndrome: Overview

Brugada syndrome

artículo científico publicado en 2006

Brugada syndrome and ischemia-induced ST-segment elevation. Similarities and differences.

artículo científico publicado en 2005

Brugada syndrome.

artículo científico publicado en 2005

Brugada syndrome: 12 years of progression

artículo científico publicado en 2004

Brugada syndrome: 1992-2002: a historical perspective

artículo científico publicado en 2003

Brugada syndrome: a decade of progress

artículo científico publicado en 2002

Brugada syndrome: clinical, genetic, molecular, cellular and ionic aspects

artículo científico publicado en 2003

Brugada syndrome: from cell to bedside

artículo científico publicado en 2005

Brugada syndrome: recent advances and controversies.

artículo científico publicado en 2008

Brugada syndrome: report of the second consensus conference.

artículo científico publicado en 2005

Brugada syndrome: report of the second consensus conference: endorsed by the Heart Rhythm Society and the European Heart Rhythm Association.

artículo científico publicado en 2005

Brugada-like electrocardiographic pattern.

artículo científico publicado en 2003

Brugada-like syndrome in infancy presenting with rapid ventricular tachycardia and intraventricular conduction delay.

artículo científico publicado en 2011

Call “the Cleaners”

scientific article published on 11 July 2015

Can inhibition of IKur promote atrial fibrillation?

artículo científico publicado en 2008

Cardiac repolarization. The long and short of it.

artículo científico publicado en 2005

Cardiomyocyte calcium cycling in a naturally occurring German shepherd dog model of inherited ventricular arrhythmia and sudden cardiac death

article

Case scenario: anesthesia-related cardiac arrest in a child with Timothy syndrome

artículo científico publicado en 2012

Cellular and Ionic Mechanisms Underlying Erythromycin-Induced Long QT Intervals and Torsade de Pointes

scientific article published on 01 December 1996

Cellular and ionic basis for the sex-related difference in the manifestation of the Brugada syndrome and progressive conduction disease phenotypes

artículo científico publicado en 2003

Cellular and ionic mechanisms responsible for the Brugada syndrome

artículo científico publicado en 2000

Cellular and ionic mechanisms underlying the effects of cilostazol, milrinone, and isoproterenol to suppress arrhythmogenesis in an experimental model of early repolarization syndrome.

artículo científico publicado en 2016

Cellular and subcellular alternans in the canine left ventricle

artículo científico publicado en 2007

Cellular basis and mechanism underlying normal and abnormal myocardial repolarization and arrhythmogenesis.

artículo científico publicado en 2004

Cellular basis for QT dispersion.

artículo científico publicado en 1998

Cellular basis for arrhythmogenesis in an experimental model of the SQT1 form of the short QT syndrome

artículo científico publicado en 2008

Cellular basis for atrial fibrillation in an experimental model of short QT1: implications for a pharmacological approach to therapy.

artículo científico publicado en 2009

Cellular basis for electrocardiographic and arrhythmic manifestations of Andersen-Tawil syndrome (LQT7).

artículo científico publicado en 2006

Cellular basis for long QT, transmural dispersion of repolarization, and torsade de pointes in the long QT syndrome

artículo científico publicado en 1999

Cellular basis for the electrocardiographic and arrhythmic manifestations of Timothy syndrome: effects of ranolazine

artículo científico publicado en 2007

Cellular basis for the monophasic action potential. Which electrode is the recording electrode?

artículo científico publicado en 2004

Cellular basis for the normal T wave and the ECG manifestations of the long QT syndrome

Cellular basis for the repolarization waves of the ECG.

artículo científico publicado en 2006

Cellular mechanism and arrhythmogenic potential of T-wave alternans in the Brugada syndrome

artículo científico publicado en 2007

Cellular mechanism underlying hypothermia-induced ventricular tachycardia/ventricular fibrillation in the setting of early repolarization and the protective effect of quinidine, cilostazol, and milrinone

artículo científico publicado en 2014

Cellular mechanisms underlying the development of catecholaminergic ventricular tachycardia.

artículo científico publicado en 2005

Cellular mechanisms underlying the effects of milrinone and cilostazol to suppress arrhythmogenesis associated with Brugada syndrome

artículo científico publicado en 2013

Cellular mechanisms underlying the long QT syndrome.

artículo científico publicado en 2002

Cellular, Molecular, and Pharmacologic Mechanisms Underlying Drug-Induced Cardiac Arrhythmogenesis

scholarly article

Chromanol 293B inhibits slowly activating delayed rectifier and transient outward currents in canine left ventricular myocytes

artículo científico publicado en 2001

Cisapride-induced transmural dispersion of repolarization and torsade de pointes in the canine left ventricular wedge preparation during epicardial stimulation

artículo científico publicado en 2003

Clinical approaches to tachyarrhythmias, volume 10: The brugada syndrome

Clinical relevance of cardiac arrhythmias generated by afterdepolarizations. Role of M cells in the generation of U waves, triggered activity and torsade de pointes.

artículo científico publicado en 1994

Coexistence of atrioventricular accessory pathways and drug-induced type 1 Brugada pattern

artículo científico publicado en 2018

Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death

artículo científico publicado en 2013

Comparison of electrophysiological and antiarrhythmic effects of vernakalant, ranolazine, and sotalol in canine pulmonary vein sleeve preparations.

artículo científico publicado en 2011

Comparison of the effects of a transient outward potassium channel activator on currents recorded from atrial and ventricular cardiomyocytes

artículo científico publicado en 2011

Compound heterozygous mutations P336L and I1660V in the human cardiac sodium channel associated with the Brugada syndrome

artículo científico publicado en 2006

Coordinated down-regulation of KCNQ1 and KCNE1 expression contributes to reduction of I(Ks) in canine hypertrophied hearts.

artículo científico publicado en 2003

Correspondence

artículo científico publicado en 1997

Descripción de la utilización de cuñas ventriculares aisladas de corazón canino en el laboratorio de electrofisiología experimental

Development of a coronary-perfused interventricular septal preparation as a model for studying the role of the septum in arrhythmogenesis

artículo científico publicado en 2007

Developmental changes in expression and biophysics of ion channels in the canine ventricle

artículo científico publicado en 2013

Diagnostic and genetic aspects of the Brugada and other inherited arrhythmias syndromes.

artículo científico publicado en 2007

Differences in the electrophysiologic response of four canine ventricular cell types to α1-adrenergic agonists

artículo científico publicado en 1999

Differential effects of beta-adrenergic agonists and antagonists in LQT1, LQT2 and LQT3 models of the long QT syndrome.

artículo científico publicado en 2000

Differential effects of the transient outward K(+) current activator NS5806 in the canine left ventricle

artículo científico publicado en 2009

Dimethyl lithospermate B, an extract of Danshen, suppresses arrhythmogenesis associated with the Brugada syndrome.

artículo científico publicado en 2006

Divergent expression of delayed rectifier K+ channel subunits during mouse heart development

article

Does Tpeak-Tend provide an index of transmural dispersion of repolarization?

artículo científico publicado en 2007

Drug-induced Brugada syndrome

Drug-induced Channelopathies

Drug-induced QT-interval shortening following antiepileptic treatment with oral rufinamide.

artículo científico publicado en 2012

Drug-induced spatial dispersion of repolarization

artículo científico publicado en 2008

Drug-induced torsades de pointes and implications for drug development.

artículo científico publicado en 2004

Dual variation in SCN5A and CACNB2b underlies the development of cardiac conduction disease without Brugada syndrome.

artículo científico publicado en 2009

ECG phenomenon of idiopathic and paradoxical short QT intervals

artículo científico publicado en 2002

Early repolarization syndrome: a decade of progress

artículo científico publicado en 2013

Early repolarization syndrome: clinical characteristics and possible cellular and ionic mechanisms.

artículo científico publicado en 2000

Effect of Wenxin Keli and quinidine to suppress arrhythmogenesis in an experimental model of Brugada syndrome ⬇️

artículo científico publicado en 2013

Effect of epicardial or biventricular pacing to prolong QT interval and increase transmural dispersion of repolarization: does resynchronization therapy pose a risk for patients predisposed to long QT or torsade de pointes?

artículo científico publicado en 2003

Electrical Diseases of the Heart

Electrocardiographic changes predicting sudden death in propofol-related infusion syndrome.

artículo científico publicado en 2006

Electromechanical coupling in patients with the short QT syndrome: further insights into the mechanoelectrical hypothesis of the U wave.

artículo científico publicado en 2007

Electrophysiologic and antiarrhythmic effects of AZD1305 in canine pulmonary vein sleeves

artículo científico publicado en 2010

Electrophysiologic basis for the antiarrhythmic actions of ranolazine ⬇️

artículo científico publicado el 21 de marzo de 2011

Electrophysiologic characteristics and pharmacologic response of human cardiomyocytes isolated from a patient with hypertrophic cardiomyopathy

artículo científico publicado en 2013

Electrophysiologic characteristics of M cells in the canine left ventricular free wall

artículo científico publicado en 1995

Electrophysiological characteristics of canine superior vena cava sleeve preparations: effect of ranolazine

artículo científico publicado en 2012

Electrophysiological effects of ranolazine, a novel antianginal agent with antiarrhythmic properties

artículo científico publicado en 2004

Empiric quinidine therapy for asymptomatic Brugada syndrome: time for a prospective registry

artículo científico publicado en 2008

Enhancing rare variant interpretation in inherited arrhythmias through quantitative analysis of consortium disease cohorts and population controls

artículo científico publicado en 2020

Epicardial Substrate as a Target for Radiofrequency Ablation in an Experimental Model of Early Repolarization Syndrome

artículo científico publicado en 2018

Epicardial activation of left ventricular wall prolongs QT interval and transmural dispersion of repolarization: implications for biventricular pacing

artículo científico publicado en 2004

Erratum: Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death

scholarly article published in Nature Genetics

Evidence for the presence of M cells in the guinea pig ventricle

artículo científico publicado en 1996

Expert's opinion

Extending the conditions of application of an inversion of the Hodgkin-Huxley gating model

artículo científico publicado en 2013

Extracellular proton depression of peak and late Na⁺ current in the canine left ventricle

artículo científico publicado en 2011

Fever accentuates transmural dispersion of repolarization and facilitates development of early afterdepolarizations and torsade de pointes under long-QT Conditions

artículo científico publicado en 2008

Fever-induced Brugada pattern: how common is it and what does it mean?

artículo científico publicado en 2013

Foreword: Brugada syndrome

Functional effects of KCNE3 mutation and its role in the development of Brugada syndrome

artículo científico publicado en 2008

Functional expression of "cardiac-type" Nav1.5 sodium channel in canine intracardiac ganglia.

artículo científico publicado en 2006

Functionally distinct sodium channels in ventricular epicardial and endocardial cells contribute to a greater sensitivity of the epicardium to electrical depression.

artículo científico publicado en 2008

Further Insights in the Most Common SCN5A Mutation Causing Overlapping Phenotype of Long QT Syndrome, Brugada Syndrome, and Conduction Defect

artículo científico publicado en 2016

Further insights into the effect of quinidine in short QT syndrome caused by a mutation in HERG

artículo científico publicado en 2005

Gain of function in IKs secondary to a mutation in KCNE5 associated with atrial fibrillation

artículo científico publicado en 2008

Genetic and biophysical basis for bupivacaine-induced ST segment elevation and VT/VF. Anesthesia unmasked Brugada syndrome

artículo científico publicado en 2006

Genetic and biophysical basis of sudden unexplained nocturnal death syndrome (SUNDS), a disease allelic to Brugada syndrome

artículo científico publicado en 2002

Genetic basis and molecular mechanism for idiopathic ventricular fibrillation

artículo científico publicado en 1998

Genetic basis of Brugada syndrome

artículo científico publicado en 2007

Genetic predisposition and cellular basis for ischemia-induced ST-segment changes and arrhythmias

artículo científico publicado en 2007

Genetic, molecular and cellular mechanisms underlying the J wave syndromes

artículo científico

Genetics and Cellular Mechanisms of the J Wave Syndromes

Genetics and Sinus Node Dysfunction

artículo científico publicado en 2009

HMR 1556, a potent and selective blocker of slowly activating delayed rectifier potassium current

artículo científico publicado en 2003

Heterogeneity and cardiac arrhythmias: an overview.

artículo científico publicado en 2007

Heterogeneity of cellular repolarization in LQTS: the role of M cells

article published in 2001

High prevalence of concealed Brugada syndrome in patients with atrioventricular nodal reentrant tachycardia

artículo científico publicado en 2015

How Do Atrial-Selective Drugs Differ From Antiarrhythmic Drugs Currently Used in the Treatment of Atrial Fibrillation?

artículo científico publicado en 2008

How Do Atrial-Selective Drugs Differ From Antiarrhythmic Drugs Currently Used in the Treatment of Atrial Fibrillation?

artículo científico publicado en 2008

Identification and characterization of a transient outward K+ current in human induced pluripotent stem cell-derived cardiomyocytes.

artículo científico publicado en 2013

Identification of a novel de novo mutation associated with PRKAG2 cardiac syndrome and early onset of heart failure

artículo científico publicado en 2013

Identification of a novel loss-of-function calcium channel gene mutation in short QT syndrome (SQTS6)

scientific journal article

Identification of specific pluripotent stem cell death--inducing small molecules by chemical screening.

artículo científico publicado en 2012

Impact of Ancestral Differences and Reassessment of the Classification of Previously Reported Pathogenic Variants in Patients With Brugada Syndrome in the Genomic Era: A SADS-TW BrS Registry

scholarly article by Ching-Yu Julius Chen et al published 2018 in Frontiers in Genetics

In vivo human demonstration of phase 2 reentry

artículo científico publicado en 2005

Induced pluripotent stem cells as a model for accelerated patient- and disease-specific drug discovery.

artículo científico publicado en 2010

Inferolateral J-wave syndromes: A reflection of abnormal repolarization, depolarization, or both?

scientific article published on 20 November 2018

Inherited Arrhythmogenic Diseases

Inhibition of IKr potentiates development of atrial-selective INa block leading to effective suppression of atrial fibrillation

artículo científico publicado en 2014

Inter-Regulation of Kv4.3 and Voltage-Gated Sodium Channels Underlies Predisposition to Cardiac and Neuronal Channelopathies

scientific article published on 17 July 2020

Intravenous drug challenge using flecainide and ajmaline in patients with Brugada syndrome

artículo científico publicado en 2005

Ion channels and ventricular arrhythmias: cellular and ionic mechanisms underlying the Brugada syndrome

artículo científico publicado en 1999

Ionic and cellular basis for the predominance of the Brugada syndrome phenotype in males

artículo científico publicado en 2002

Ionic and cellular mechanisms underlying the development of acquired Brugada syndrome in patients treated with antidepressants.

artículo científico publicado en 2011

Ionic, molecular, and cellular bases of QT-interval prolongation and torsade de pointes.

artículo científico publicado en 2007

Is a narrow and tall QRS complex an ECG marker for sudden death?

artículo científico publicado en 2008

Is extensive atrial fibrosis in the setting of heart failure associated with a reduced atrial fibrillation burden?

artículo científico publicado en 2018

Is there a significant transmural gradient in repolarization time in the intact heart? Cellular basis of the T wave: a century of controversy.

artículo científico publicado en 2009

Ischemic ventricular arrhythmias: experimental models and their clinical relevance

artículo científico publicado en 2011

J wave syndromes as a cause of malignant cardiac arrhythmias

J wave syndromes.

artículo científico publicado en 2009

J wave syndromes: molecular and cellular mechanisms

artículo científico publicado en 2013

J-Wave syndromes expert consensus conference report: Emerging concepts and gaps in knowledge

artículo científico publicado en 2016

J-Wave syndromes expert consensus conference report: Emerging concepts and gaps in knowledge.

artículo científico publicado en 2016

J-wave syndromes. from cell to bedside

artículo científico publicado en 2011

J-wave syndromes: Brugada and early repolarization syndromes

artículo científico publicado en 2015

KCNE2 modulation of Kv4.3 current and its potential role in fatal rhythm disorders

artículo científico publicado en 2009

LQT5 masquerading as LQT2: a dominant negative effect of KCNE1-D85N rare polymorphism on KCNH2 current.

artículo científico publicado en 2011

Larger late sodium conductance in M cells contributes to electrical heterogeneity in canine ventricle

artículo científico publicado en 2001

Late potentials and the Brugada syndrome**Editorials published in the Journal of the American College of Cardiologyreflect the views of the authors and do not necessarily represent the views of JACCor the American College of Cardiology

artículo científico publicado en 2002

Late-phase 3 EAD. A unique mechanism contributing to initiation of atrial fibrillation

artículo científico publicado en 2006

Lidocaine-induced Brugada syndrome phenotype linked to a novel double mutation in the cardiac sodium channel.

artículo científico publicado en 2008

Link between hypothermia and the Brugada syndrome.

artículo científico publicado en 2004

Long QT, syndactyly, joint contractures, stroke and novel CACNA1C mutation: expanding the spectrum of Timothy syndrome

artículo científico publicado en 2011

Long-term follow-up of individuals with the electrocardiographic pattern of right bundle-branch block and ST-segment elevation in precordial leads V1 to V3.

artículo científico publicado en 2002

Loss-of-function mutations in the cardiac calcium channel underlie a new clinical entity characterized by ST-segment elevation, short QT intervals, and sudden cardiac death

artículo científico publicado en 2007

M cells in the human heart

artículo científico publicado en 2010

Malignant early repolarization: It's the T-wave, stupid….

artículo científico publicado en 2015

Management of ventricular arrhythmias in suspected channelopathies

artículo científico publicado en 2015

Maximum diastolic potential of human induced pluripotent stem cell-derived cardiomyocytes depends critically on I(Kr).

artículo científico publicado en 2012

Mechanisms Underlying Arrhythmogenesis in Long QT Syndrome

Mechanisms Underlying Epicardial Radiofrequency Ablation to Suppress Arrhythmogenesis in Experimental Models of Brugada Syndrome

artículo científico publicado en 2016

Mechanisms Underlying the Actions of Antidepressant and Antipsychotic Drugs That Cause Sudden Cardiac Arrest

Mechanisms of Action of Antiarrhythmic Drugs in Atrial Fibrillation

Mechanisms of Cardiac Arrhythmia

Mechanisms of atrial-selective block of Na⁺ channels by ranolazine: I. Experimental analysis of the use-dependent block

artículo científico publicado en 2011

Mechanisms of atrial-selective block of Na⁺ channels by ranolazine: II. Insights from a mathematical model

artículo científico publicado en 2011

Mechanisms underlying atrial-selective block of sodium channels by Wenxin Keli: Experimental and theoretical analysis.

artículo científico

Mechanisms underlying the development of the electrocardiographic and arrhythmic manifestations of early repolarization syndrome

artículo científico publicado en 2013

Minimum Information about a Cardiac Electrophysiology Experiment (MICEE): standardised reporting for model reproducibility, interoperability, and data sharing.

artículo científico publicado en 2011

Mode of onset of ventricular fibrillation in patients with early repolarization pattern vs. Brugada syndrome

artículo científico publicado en 2009

Modulation of canine cardiac sodium current by Apelin

artículo científico publicado en 2009

Modulation of transmural repolarization

artículo científico publicado en 2005

Molecular Genetics of Arrhythmias and Cardiovascular Conditions Associated with Arrhythmias

article

Molecular and Functional Characterization of Rare CACNA1C Variants in Sudden Unexplained Death in the Young

artículo científico publicado en 2016

Molecular genetic and functional association of Brugada and early repolarization syndromes with S422L missense mutation in KCNJ8

artículo científico publicado en 2011

Molecular genetics of arrhythmias and cardiovascular conditions associated with arrhythmias

artículo científico publicado en 2003

Molecular mechanisms underlying the long QT syndrome ⬇️

artículo científico publicado el 1 de enero de 2002

Multiple arrhythmic syndromes in a newborn, owing to a novel mutation in SCN5A

artículo científico publicado en 2011

Multiple serial ECGs aid with the diagnosis and prognosis of Brugada syndrome

Mutation in Nav1.5 Associated with Brugada Syndrome - a Mutational Hotspot?

Mutations in SCN10A are responsible for a large fraction of cases of Brugada syndrome

artículo científico publicado en 2014

Mutations in the cardiac L-type calcium channel associated with inherited J-wave syndromes and sudden cardiac death.

artículo científico publicado en 2010

New approaches to antiarrhythmic therapy: emerging therapeutic applications of the cell biology of cardiac arrhythmias(1).

artículo científico publicado en 2001

New developments in atrial antiarrhythmic drug therapy

artículo científico publicado en 2010

New pharmacological strategies for the treatment of atrial fibrillation

artículo científico publicado en 2009

Novel Pharmacological Targets for the Management of Atrial Fibrillation

scholarly article

Novel Therapeutic Strategies for the Management of Ventricular Arrhythmias Associated with the Brugada Syndrome

artículo científico publicado en 2015

Novel Timothy syndrome mutation leading to increase in CACNA1C window current

artículo científico publicado en 2014

Novel mutation in the SCN5A gene associated with arrhythmic storm development during acute myocardial infarction

artículo científico publicado en 2007

Novel mutations in domain I of SCN5A cause Brugada syndrome

artículo científico publicado en 2002

Novel mutations in the KCND3-encoded Kv4.3 K+ channel associated with autopsy-negative sudden unexplained death ⬇️

artículo científico publicado el 27 de marzo de 2012

Novel pharmacological targets for the rhythm control management of atrial fibrillation.

artículo científico publicado en 2011

Occurrence of "J waves" in 12-lead ECG as a marker of acute ischemia and their cellular basis

artículo científico publicado en 2007

Optical and electrical recordings from isolated coronary-perfused ventricular wedge preparations.

artículo científico publicado en 2012

Overlapping LQT1 and LQT2 phenotype in a patient with long QT syndrome associated with loss-of-function variations in KCNQ1 and KCNH2

artículo científico publicado en 2010

Overview of Basic Mechanisms of Cardiac Arrhythmia ⬇️

artículo científico publicado el 1 de marzo de 2011

PQ segment depression in patients with short QT syndrome: a novel marker for diagnosing short QT syndrome?

artículo científico publicado en 2014

Pathophysiology of atrial fibrillation

Pharmacological approach to the treatment of long and short QT syndromes

artículo científico publicado en 2008

Phase 2 reentry as a mechanism of initiation of circus movement reentry in canine epicardium exposed to simulated ischemia

artículo científico publicado en 1996

Phenotypic characterization of a large European family with Brugada syndrome displaying a sudden unexpected death syndrome mutation in SCN5A:.

artículo científico publicado en 2004

Phenotypical manifestations of mutations in the genes encoding subunits of the cardiac voltage-dependent L-type calcium channel

artículo científico publicado en 2011

Physiological consequences of transient outward K+ current activation during heart failure in the canine left ventricle.

artículo científico publicado en 2012

Pooled Analysis of Risk Stratification of Spontaneous Type 1 Brugada ECG: Focus on the Influence of Gender and EPS

Postpacing abnormal repolarization in catecholaminergic polymorphic ventricular tachycardia associated with a mutation in the cardiac ryanodine receptor gene.

artículo científico publicado en 2011

Potent antiarrhythmic effects of chronic amiodarone in canine pulmonary vein sleeve preparations

scientific article published on 27 February 2009

Potential proarrhythmic effects of biventricular pacing

artículo científico publicado en 2005

Preface

Prominent I(Ks) in epicardium and endocardium contributes to development of transmural dispersion of repolarization but protects against development of early afterdepolarizations

artículo científico publicado en 2002

Proposed Diagnostic Criteria for the Brugada Syndrome

article published in 2002

Proposed diagnostic criteria for the Brugada syndrome

artículo científico publicado en 2002

Proposed diagnostic criteria for the Brugada syndrome: consensus report

artículo científico publicado en 2002

Provocation of sudden heart rate oscillation with adenosine exposes abnormal QT responses in patients with long QT syndrome: a bedside test for diagnosing long QT syndrome.

artículo científico publicado en 2005

Pulmonary Vein Sleeves as a Pharmacologic Model for the Study of Atrial Fibrillation

artículo científico publicado en 2010

Quinidine: a valuable medication joins the list of 'endangered species'.

artículo científico publicado en 2007

Ranolazine effectively suppresses atrial fibrillation in the setting of heart failure.

artículo científico publicado en 2014

Ranolazine for Congenital Long-QT Syndrome Type III: Experimental and Long-Term Clinical Data

artículo científico publicado en 2016

Ranolazine versus amiodarone for prevention of postoperative atrial fibrillation.

artículo científico publicado en 2011

Ranolazine: a new antiarrhythmic agent for patients with non-ST-segment elevation acute coronary syndromes?

artículo científico publicado en 2008

Rare syndromes, commotio cordis, sudden death in athletes

Rate dependence of action potential duration and refractoriness in canine ventricular endocardium differs from that of epicardium: role of the transient outward current.

artículo científico publicado en 1989

Rate-dependent effects of vernakalant in the isolated non-remodeled canine left atria are primarily due to block of the sodium channel: comparison with ranolazine and dl-sotalol

artículo científico publicado en 2012

Rationale for the use of the terms J-wave syndromes and early repolarization.

artículo científico publicado en 2011

Recognition and Clinical Implications of High Prevalence of Migraine in Patients with Brugada Syndrome and Drug-Induced Type 1 Brugada Pattern

scientific article published on 15 October 2020

Reinduction of atrial fibrillation immediately after termination of the arrhythmia is mediated by late phase 3 early afterdepolarization-induced triggered activity

artículo científico publicado en 2003

Reply to the Editor- Tpeak-Tend is alive and well

scientific article published on 23 January 2019

Reply to the Editor--PQ-segment depression in short QT syndrome patients: a novel marker for diagnosing short QT syndrome?

artículo científico publicado en 2014

Reply to the Editor–Mechanoelectrical factors in M-cell debate

Resolving the M-cell debate: why and how.

artículo científico publicado en 2011

Risk stratification [corrected] of Brugada syndrome revisited.

artículo científico publicado en 2008

Risk stratification in Brugada syndrome: Clinical characteristics, electrocardiographic parameters, and auxiliary testing

artículo científico publicado en 2015

Role of Late Sodium Channel Current Block in the Management of Atrial Fibrillation ⬇️

artículo científico publicado el 1 de febrero de 2013

Role of M cells in acquired long QT syndrome, U waves, and torsade de pointes

artículo científico publicado en 1995

Role of late sodium current in modulating the proarrhythmic and antiarrhythmic effects of quinidine

artículo científico publicado en 2008

Role of repolarization restitution in the development of coarse and fine atrial fibrillation in the isolated canine right atria

artículo científico publicado en 2005

Role of sodium and calcium channel block in unmasking the Brugada syndrome

artículo científico publicado en 2004

Role of spatial dispersion of repolarization in inherited and acquired sudden cardiac death syndromes.

artículo científico publicado en 2007

Role of transmural dispersion of repolarization in the genesis of drug-induced torsades de pointes

artículo científico publicado en 2005

Short QT syndrome. Genotype-phenotype correlations

artículo científico publicado en 2005

Short QT syndrome: from bench to bedside.

artículo científico publicado en 2010

Short QT syndrome: pharmacological treatment

artículo científico publicado en 2004

Should theophylline be added to the J wave syndrome therapeutic armamentarium?

artículo científico publicado en 2017

Sodium channel blockers identify risk for sudden death in patients with ST-segment elevation and right bundle branch block but structurally normal hearts

artículo científico publicado en 2000

Sodium pentobarbital reduces transmural dispersion of repolarization and prevents torsades de Pointes in models of acquired and congenital long QT syndrome

artículo científico publicado en 1999

Specific therapy based on the genotype and cellular mechanism in inherited cardiac arrhythmias. Long QT syndrome and Brugada syndrome

artículo científico publicado en 2005

Study of the extent of the information of cardiologists from São Paulo city, Brazil, regarding a low-prevalence entity: Brugada syndrome.

artículo científico publicado en 2008

Sudden cardiac death secondary to antidepressant and antipsychotic drugs

article by Serge Sicouri & Charles Antzelevitch published 1 March 2008 in Expert Opinion on Drug Safety

Sudden death associated with short-QT syndrome linked to mutations in HERG.

artículo científico publicado en 2003

Sympathetic modulation of the long QT syndrome

artículo científico publicado en 2002

Synergistic effect of the combination of ranolazine and dronedarone to suppress atrial fibrillation.

artículo científico publicado en 2010

Synergistic electrophysiologic and antiarrhythmic effects of the combination of ranolazine and chronic amiodarone in canine atria

artículo científico publicado en 2009

The Brugada Syndrome

The Brugada Syndrome: From Bench to Bedside

The Brugada syndrome

artículo científico publicado en 2002

The Brugada syndrome: clinical, electrophysiologic and genetic aspects.

artículo científico publicado en 1999

The Brugada syndrome: diagnostic criteria and cellular mechanisms

artículo científico publicado en 2001

The Brugada syndrome: is an implantable cardioverter defibrillator the only therapeutic option?

artículo científico publicado en 2002

The Cardiac Electrophysiology Society abstracts that have published in the November issue of HeartRhythm Journal (2013;10:1741-1754) were inadvertently posted on PubMed. These abstracts were not peer-reviewed and they were posted without approval or

The Contribution of HCN4 to normal sinus node function in humans and animal models

artículo científico publicado en 2009

The Early Repolarization Pattern: A Consensus Paper

artículo científico publicado en 2015

The Effects of Peg-Interleukin-2 and Interleukin-2 on Essential Hypertension and Cellular Immune Function in the Spontaneously Hypertensive Rat

scientific article published on 01 March 1993

The J Wave Syndromes and their Role in Sudden Cardiac Death.

artículo científico publicado en 2011

The M cell: its contribution to the ECG and to normal and abnormal electrical function of the heart

artículo científico publicado en 1999

The Role of Spatial Dispersion of Repolarization and Intramural Reentry in Inherited and Acquired Sudden Cardiac Death Syndromes

The acquired Brugada syndrome and the paradox of choice.

artículo científico publicado en 2009

The arrhythmogenic consequences of increasing late INa in the cardiomyocyte

artículo científico publicado en 2013

The cardiologists' worst nightmare sudden death from "benign" ventricular arrhythmias

artículo científico publicado en 2005

The homeodomain transcription factor Irx5 establishes the mouse cardiac ventricular repolarization gradient

scientific journal article

The pathophysiological mechanism underlying Brugada syndrome: depolarization versus repolarization

artículo científico publicado en 2010

The phenomenon of "QT stunning": the abnormal QT prolongation provoked by standing persists even as the heart rate returns to normal in patients with long QT syndrome

artículo científico publicado en 2012

The potential for QT prolongation and pro-arrhythmia by non-anti-arrhythmic drugs: clinical and regulatory implications. Report on a Policy Conference of the European Society of Cardiology.

artículo científico publicado en 2000

The response of the QT interval to the brief tachycardia provoked by standing: a bedside test for diagnosing long QT syndrome

artículo científico publicado en 2010

The role of late I Na in development of cardiac arrhythmias

artículo científico publicado en 2014

The role of local voltage potentials in outflow tract ectopy

artículo científico publicado en 2010

The role of sodium channel current in modulating transmural dispersion of repolarization and arrhythmogenesis.

artículo científico publicado en 2006

Theophylline: The forgotten antiarrhythmic drug… now for malignant early repolarization

artículo científico publicado en 2017

Tissue-specific effects of acetylcholine in the canine heart.

artículo científico publicado en 2013

To the Editor Response

Torsades de pointes following acute myocardial infarction: evidence for a deadly link with a common genetic variant

artículo científico publicado en 2012

Tpeak-Tend and Tpeak-Tend dispersion as risk factors for ventricular tachycardia/ventricular fibrillation in patients with the Brugada syndrome.

artículo científico publicado en 2006

Tpeak-Tend as a predictor of ventricular arrhythmogenesis

artículo científico publicado en 2017

Tpeak-Tend interval as a marker of arrhythmic risk

artículo científico publicado en 2019

Tpeak-tend interval as a marker of arrhythmic risk in early repolarization syndrome

artículo científico publicado en 2019

Traditional Chinese Medicine and Vascular Disease

artículo científico publicado en 2015

Transcriptional changes associated with advancing stages of heart failure underlie atrial and ventricular arrhythmogenesis.

artículo científico publicado en 2019

Transient outward current (I(to)) gain-of-function mutations in the KCND3-encoded Kv4.3 potassium channel and Brugada syndrome

scientific journal article

Transmembrane action potential heterogeneity in the canine isolated arterially perfused right atrium: effect of IKr and IKur/Ito block

artículo científico publicado en 2004

Transmural dispersion of repolarization and arrhythmogenicity: the Brugada syndrome versus the long QT syndrome

artículo científico publicado en 1999

Transmural dispersion of repolarization and the T wave

artículo científico publicado en 2001

Transmural heterogeneity of calcium activity and mechanical function in the canine left ventricle

artículo científico publicado en 2003

Transseptal dispersion of repolarization and its role in the development of Torsade de Pointes arrhythmias

artículo científico publicado en 2009

Unique topographical distribution of M cells underlies reentrant mechanism of torsade de pointes in the long-QT syndrome

artículo científico publicado en 2002

Unraveling the Enigma of Bangungut: Is Sudden Unexplained Nocturnal Death Syndrome (SUNDS) in the Philippines a Disease Allelic to the Brugada Syndrome? ⬇️

artículo científico publicado el 1 de julio de 2011

Usefulness of exercise test in the diagnosis of short QT syndrome

artículo científico publicado en 2015

Value of electrocardiographic parameters and ajmaline test in the diagnosis of Brugada syndrome caused by SCN5A mutations

artículo científico publicado en 2004

Ventricular fibrillation associated with complete right bundle branch block

artículo científico publicado en 2013

When u say "U Waves," what do u mean?

artículo científico publicado en 2004

[Genetic and molecular basis for sodium channel-mediated Brugada syndrome].

artículo científico publicado en 2013

Lista de obras de Charles Antzelevitch

A CACNA1C variant associated with reduced voltage-dependent inactivation, increased CaV1.2 channel window current, and arrhythmogenesis

A common single nucleotide polymorphism can exacerbate long-QT type 2 syndrome leading to sudden infant death.

A complete right bundle-branch block masking Brugada syndrome

A gain-of-function I(K-ATP) mutation and its role in sudden cardiac death associated with J-wave syndromes

A molecular link between the sudden infant death syndrome and the long-QT syndrome

A mutation in the beta 3 subunit of the cardiac sodium channel associated with Brugada ECG phenotype

A novel mutation in KCNQ1 associated with a potent dominant negative effect as the basis for the LQT1 form of the long QT syndrome.

A novel mutation in the HCN4 gene causes symptomatic sinus bradycardia in Moroccan Jews.

A novel rare variant in SCN1Bb linked to Brugada syndrome and SIDS by combined modulation of Na(v)1.5 and K(v)4.3 channel currents

A temporal window of vulnerability for development of atrial fibrillation with advancing heart failure

A transient outward potassium current activator recapitulates the electrocardiographic manifestations of Brugada syndrome.

ABCC9 is a novel Brugada and early repolarization syndrome susceptibility gene.

ABSTRACTS

AZD1305 exerts atrial predominant electrophysiological actions and is effective in suppressing atrial fibrillation and preventing its reinduction in the dog

Abnormal repolarization as the basis for late potentials and fractionated electrograms recorded from epicardium in experimental models of Brugada syndrome

Accelerated inactivation of the L-type calcium current due to a mutation in CACNB2b underlies Brugada syndrome

Acute dronedarone is inferior to amiodarone in terminating and preventing atrial fibrillation in canine atria.

Acute myocardial ischemia: cellular mechanisms underlying ST segment elevation

Advances in the Pharmacologic Management of Atrial Fibrillation

Advances in the Pharmacological Treatment of Atrial Fibrillation ⬇️

Ajmaline-Induced Slowing of Conduction in the Right Ventricular Outflow Tract Cannot Account for ST Elevation in Patients With Type I Brugada ECG.

American Heart Association atrial fibrillation research summit: a conference report from the American Heart Association

Amplified transmural dispersion of repolarization as the basis for arrhythmogenesis in a canine ventricular-wedge model of short-QT syndrome

An international compendium of mutations in the SCN5A-encoded cardiac sodium channel in patients referred for Brugada syndrome genetic testing

Andersen-Tawil syndrome: Clinical presentation and predictors of symptomatic arrhythmias - Possible role of polymorphisms K897T in KCNH2 and H558R in SCN5A gene

Androgens and male predominance of the Brugada syndrome phenotype

Antiarrhythmic effects of losartan and enalapril in canine pulmonary vein sleeve preparations.

Antiarrhythmic effects of ranolazine in a guinea pig in vitro model of long-QT syndrome

Antiarrhythmic effects of ranolazine in canine pulmonary vein sleeve preparations.

Antiarrhythmic effects of simvastatin in canine pulmonary vein sleeve preparations

Antiarrhythmic effects of the highly selective late sodium channel current blocker GS-458967

Arrhythmogenic mechanisms of QT prolonging drugs: is QT prolongation really the problem?

Assessing predictors of drug-induced torsade de pointes.

Atria are More Sensitive Than Ventricles to GS-458967-Induced Inhibition of Late Sodium Current

Atrial fibrillation and Brugada syndrome

Atrial fibrillation in inherited cardiac channelopathies: From mechanisms to management

Atrial-selective effects of chronic amiodarone in the management of atrial fibrillation.

Atrial-selective inhibition of sodium-channel current by Wenxin Keli is effective in suppressing atrial fibrillation.

Atrial-selective prolongation of refractory period with AVE0118 is due principally to inhibition of sodium channel activity

Atrial-selective sodium channel block as a novel strategy for the management of atrial fibrillation

Atrial-selective sodium channel block as a novel strategy for the management of atrial fibrillation.

Atrial-selective sodium channel block as a strategy for suppression of atrial fibrillation

Atrial-selective sodium channel block for the treatment of atrial fibrillation.

Atrial-selective sodium channel block strategy to suppress atrial fibrillation: ranolazine versus propafenone.

Atrial-selective sodium channel blockers: do they exist?

Atrium-selective sodium channel block as a strategy for suppression of atrial fibrillation: differences in sodium channel inactivation between atria and ventricles and the role of ranolazine

Augmentation of J waves and electrical storms in patients with early repolarization

Augmentation of late sodium current unmasks the proarrhythmic effects of amiodarone.

Author's response to letter to the editor from Perez and Froelicher.

Autonomic aspects of arrhythmogenesis: the enduring and the new.

Basic mechanisms of reentrant arrhythmias

Biophysical and molecular characterization of a novel de novo KCNJ2 mutation associated with Andersen-Tawil syndrome and catecholaminergic polymorphic ventricular tachycardia mimicry

Blinded validation of the isolated arterially perfused rabbit ventricular wedge in preclinical assessment of drug-induced proarrhythmias.

Brugada Syndrome: Cellular Mechanisms and Approaches to Therapy

Brugada Syndrome: Cellular Mechanisms and Approaches to Therapy

Brugada Syndrome: Clinical, Genetic, Molecular, Cellular, and Ionic Aspects

Brugada Syndrome: Overview

Brugada syndrome

Brugada syndrome and ischemia-induced ST-segment elevation. Similarities and differences.

Brugada syndrome.

Brugada syndrome: 12 years of progression

Brugada syndrome: 1992-2002: a historical perspective

Brugada syndrome: a decade of progress

Brugada syndrome: clinical, genetic, molecular, cellular and ionic aspects

Brugada syndrome: from cell to bedside

Brugada syndrome: recent advances and controversies.

Brugada syndrome: report of the second consensus conference.

Brugada syndrome: report of the second consensus conference: endorsed by the Heart Rhythm Society and the European Heart Rhythm Association.

Brugada-like electrocardiographic pattern.

Brugada-like syndrome in infancy presenting with rapid ventricular tachycardia and intraventricular conduction delay.

Call “the Cleaners”

Can inhibition of IKur promote atrial fibrillation?

Cardiac repolarization. The long and short of it.

Cardiomyocyte calcium cycling in a naturally occurring German shepherd dog model of inherited ventricular arrhythmia and sudden cardiac death

Case scenario: anesthesia-related cardiac arrest in a child with Timothy syndrome

Cellular and Ionic Mechanisms Underlying Erythromycin-Induced Long QT Intervals and Torsade de Pointes

Cellular and ionic basis for the sex-related difference in the manifestation of the Brugada syndrome and progressive conduction disease phenotypes

Cellular and ionic mechanisms responsible for the Brugada syndrome

Cellular and ionic mechanisms underlying the effects of cilostazol, milrinone, and isoproterenol to suppress arrhythmogenesis in an experimental model of early repolarization syndrome.