Lista de obras - Michael Otmar Hengartner

A Steric-inhibition model for regulation of nucleotide exchange via the Dock180 family of GEFs

artículo científico publicado en 2005

A conserved role for SNX9-family members in the regulation of phagosome maturation during engulfment of apoptotic cells

artículo científico publicado en 2011

A dynamic physical model of cell migration, differentiation and apoptosis in Caenorhabditis elegans

artículo científico publicado en 2012

A lectin-mediated resistance of higher fungi against predators and parasites.

artículo científico publicado en 2011

A novel mouse model for inhibition of DOHH-mediated hypusine modification reveals a crucial function in embryonic development, proliferation and oncogenic transformation

scientific journal article

A pathway for phagosome maturation during engulfment of apoptotic cells

artículo científico publicado en 2008

A quantitative targeted proteomics approach to validate predicted microRNA targets in C. elegans

artículo científico publicado en 2010

A worm rich in protein: Quantitative, differential, and global proteomics in Caenorhabditis elegans

scientific article published on 14 April 2010

Activation of C. elegans cell death protein CED-9 by an amino-acid substitution in a domain conserved in Bcl-2.

artículo científico publicado en 1994

Advances in apoptosis research ⬇️

artículo científico publicado el 25 de noviembre de 1997

Alteration of the nuclear pore complex in Ca(2+)-mediated cell death.

artículo científico publicado en 2010

Aminophospholipid translocase TAT-1 promotes phosphatidylserine exposure during C. elegans apoptosis.

artículo científico publicado en 2007

Analysis of C. elegans intestinal gene expression and polyadenylation by fluorescence-activated nuclei sorting and 3'-end-seq

artículo científico publicado en 2012

Apoptosis CED-4 is a stranger no more ⬇️

artículo científico publicado el 21 de agosto de 1997

Apoptosis and the shape of death

article by Michael Otmar Hengartner published 1997 in Genesis

Apoptotic cell death under hypoxia.

artículo científico

Biotoxicity assays for fruiting body lectins and other cytoplasmic proteins

artículo científico publicado en 2010

C. elegans GLA-3 is a novel component of the MAP kinase MPK-1 signaling pathway required for germ cell survival

artículo científico publicado en 2006

C. elegans RAD-5/CLK-2 defines a new DNA damage checkpoint protein

scientific journal article

C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2.

artículo científico publicado en 1994

Caenorhabditis elegans ABL-1 antagonizes p53-mediated germline apoptosis after ionizing irradiation

artículo científico publicado en 2004

Caenorhabditis elegans DNA mismatch repair gene msh-2 is required for microsatellite stability and maintenance of genome integrity

artículo científico publicado en 2002

Caenorhabditis elegans HUS-1 is a DNA damage checkpoint protein required for genome stability and EGL-1-mediated apoptosis

artículo científico publicado en 2002

Caenorhabditis elegans N-glycan Core β-galactoside Confers Sensitivity towards Nematotoxic Fungal Galectin CGL2

artículo científico publicado en 2010

Caenorhabditis elegans contains two distinct acid sphingomyelinases.

artículo científico publicado en 1998

Caenorhabditis elegans gene ced-9 protects cells from programmed cell death

artículo científico publicado el 9 de abril de 1992

Candidate adaptor protein CED-6 promotes the engulfment of apoptotic cells in C. elegans.

artículo científico publicado en 1998

Cell biology. Tickling macrophages, a serious business

artículo científico publicado en 2004

Cell biology: divide and conquer

artículo científico publicado en 2005

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

artículo científico publicado en 2009

Cleaning up the mess: cell corpse clearance in Caenorhabditis elegans

artículo científico

Comparative analysis reveals conserved protein phosphorylation networks implicated in multiple diseases

artículo científico publicado en 2009

Comparative functional analysis of the Caenorhabditis elegans and Drosophila melanogaster proteomes

artículo científico publicado en 2009

Correction: Long-term C. elegans immobilization enables high resolution developmental studies in vivo

scientific article published on 01 June 2018

Death and more: DNA damage response pathways in the nematode C. elegans.

artículo científico publicado en 2004

Death cycle and Swiss army knives ⬇️

artículo científico publicado el 29 de enero de 1998

Deficiency of FANCD2-associated nuclease KIAA1018/FAN1 sensitizes cells to interstrand crosslinking agents

artículo científico publicado en 2010

Deleted in cancer 1 (DICE1) is an essential protein controlling the topology of the inner mitochondrial membrane in C. elegans

artículo científico publicado en 2006

Developmental apoptosis in C. elegans: a complex CEDnario

artículo científico publicado en 2006

Differential regulation of DNA damage response activation between somatic and germline cells in Caenorhabditis elegans.

artículo científico publicado en 2012

Differential regulation of germ line apoptosis and germ cell differentiation by CPEB family members in C. elegans

artículo científico publicado en 2017

Dimerization of the fungal defense lectin CCL2 is essential for its toxicity against nematodes.

artículo científico publicado en 2016

Dock180 and ELMO1 proteins cooperate to promote evolutionarily conserved Rac-dependent cell migration

artículo científico publicado en 2004

Dying to hold you

artículo científico publicado en 2008

Engulfment genes cooperate with ced-3 to promote cell death in Caenorhabditis elegans

artículo científico publicado en 2001

Epigenetic regulation of histone H3 serine 10 phosphorylation status by HCF-1 proteins in C. elegans and mammalian cells

artículo científico publicado en 2007

Erratum: A quantitative targeted proteomics approach to validate predicted microRNA targets in C. elegans

scholarly article published in Nature Methods

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.

artículo científico publicado en 2014

Establishing a Blueprint for CED-3-dependent Killing through Identification of Multiple Substrates for This Protease

artículo científico publicado en 2007

Finding function in novel targets: C. elegans as a model organism

artículo científico publicado en 2006

Functional identification of optimized RNAi triggers using a massively parallel sensor assay

artículo científico publicado en 2011

Generic comparison of protein inference engines

artículo científico publicado en 2011

Genetic control of programmed cell death and aging in the nematode Caenorhabditis elegans.

artículo científico publicado en 1997

Genetics of apoptosis

artículo científico publicado en 1997

Genome-wide RNAi identifies p53-dependent and -independent regulators of germ cell apoptosis in C. elegans

scientific article published on 01 November 2004

Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes.

artículo científico publicado en 2009

HIF-1 antagonizes p53-mediated apoptosis through a secreted neuronal tyrosinase

artículo científico publicado en 2010

How the worm removes corpses: the nematode C. elegans as a model system to study engulfment.

artículo científico publicado en 2001

Identification of two signaling submodules within the CrkII/ELMO/Dock180 pathway regulating engulfment of apoptotic cells.

artículo científico publicado en 2007

LEM-3 - A LEM domain containing nuclease involved in the DNA damage response in C. elegans

artículo científico publicado en 2012

Long-term C. elegans immobilization enables high resolution developmental studies in vivo.

artículo científico publicado en 2018

Loss of Acetylcholine Signaling Reduces Cell Clearance Deficiencies in Caenorhabditis elegans

artículo científico publicado en 2016

Loss of the RhoGAP SRGP-1 promotes the clearance of dead and injured cells in Caenorhabditis elegans

artículo científico publicado en 2010

MINA-1 and WAGO-4 are part of regulatory network coordinating germ cell death and RNAi in C. elegans

scientific article published on 06 February 2019

Methylated glycans as conserved targets of animal and fungal innate defense.

artículo científico publicado en 2014

Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells

artículo científico publicado en 2011

Model organisms proteomics--from holobionts to human nutrition.

artículo científico publicado en 2013

Modeling the binding specificity of the RNA-binding protein GLD-1 suggests a function of coding region-located sites in translational repression

artículo científico

Molecular basis for galactosylation of core fucose residues in invertebrates: identification of caenorhabditis elegans N-glycan core alpha1,6-fucoside beta1,4-galactosyltransferase GALT-1 as a member of a novel glycosyltransferase family

artículo científico publicado en 2009

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

artículo científico publicado en 2012

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

artículo científico publicado en 2018

NER and HR pathways act sequentially to promote UV-C-induced germ cell apoptosis in Caenorhabditis elegans ⬇️

artículo científico publicado el 10 de diciembre de 2010

Natural Genetic Variation Differentially Affects the Proteome and Transcriptome in Caenorhabditis elegans.

artículo científico publicado en 2016

Natural Genetic Variation Influences Protein Abundances in C. elegans Developmental Signalling Pathways.

artículo científico publicado en 2016

Nematotoxicity of Marasmius oreades agglutinin (MOA) depends on glycolipid binding and cysteine protease activity.

artículo científico publicado en 2011

No death without life: vital functions of apoptotic effectors

artículo científico publicado en 2008

Nonapoptotic Role for Apaf-1 in the DNA Damage Checkpoint

Nonapoptotic role for Apaf-1 in the DNA damage checkpoint

artículo científico publicado en 2007

PH domain of ELMO functions in trans to regulate Rac activation via Dock180

artículo científico publicado en 2004

PaxDb, a database of protein abundance averages across all three domains of life

artículo científico publicado en 2012

Phagocytosis of apoptotic cells is regulated by a UNC-73/TRIO-MIG-2/RhoG signaling module and armadillo repeats of CED-12/ELMO

artículo científico publicado en 2004

Plasticity of the β-Trefoil Protein Fold in the Recognition and Control of Invertebrate Predators and Parasites by a Fungal Defence System

artículo científico publicado en 2012

Post-transcriptional control of executioner caspases by RNA-binding proteins

scientific article published on October 2016

Predictive Modelling of Stem Cell Differentiation and Apoptosis in C. elegans

Programmed cell death in Caenorhabditis elegans

article

Programmed cell death in invertebrates.

artículo científico publicado en 1996

Programmed cell death. A rich harvest.

artículo científico publicado en 1994

Programmed cell death: from development to disease

article

Protection of C. elegans from anoxia by HYL-2 ceramide synthase

artículo científico publicado en 2009

Protein identification false discovery rates for very large proteomics data sets generated by tandem mass spectrometry

artículo científico publicado en 2009

RIP-chip-SRM--a new combinatorial large-scale approach identifies a set of translationally regulated bantam/miR-58 targets in C. elegans

artículo científico publicado en 2012

Rearrangements of the nucleosome structure in chromatin by poly(ADP-ribose)

artículo científico publicado en 1992

Regulation of nicotinic receptor trafficking by the transmembrane Golgi protein UNC-50.

artículo científico publicado en 2007

Ribosome synthesis and MAPK activity modulate ionizing radiation-induced germ cell apoptosis in Caenorhabditis elegans

artículo científico publicado en 2013

Shotgun proteomics data from multiple organisms reveals remarkable quantitative conservation of the eukaryotic core proteome

artículo científico publicado en 2010

Small GTPase CDC-42 promotes apoptotic cell corpse clearance in response to PAT-2 and CED-1 in C. elegans

artículo científico publicado en 2014

Sugar antennae for guidance signals: syndecans and glypicans integrate directional cues for navigating neurons.

artículo científico publicado en 2006

Syndecan regulates cell migration and axon guidance in C. elegans

artículo científico publicado en 2005

Tales of cannibalism, suicide, and murder: Programmed cell death in C. elegans

artículo científico publicado en 2005

The HUPO initiative on Model Organism Proteomes, iMOP.

artículo científico publicado en 2012

The Wnt pathway controls cell death engulfment, spindle orientation, and migration through CED-10/Rac

artículo científico publicado en 2010

The biochemistry of apoptosis

artículo científico publicado en 2000

The future of model organisms in human disease research

artículo científico publicado en 2011

The genes pme-1 and pme-2 encode two poly(ADP-ribose) polymerases in Caenorhabditis elegans

artículo científico publicado en 2002

The genetics of programmed cell death in the nematode Caenorhabditis elegans.

artículo científico publicado en 1994

The initiative on Model Organism Proteomes (iMOP) Session September 6, 2011, Geneva, Switzerland

artículo científico publicado en 2012

The phosphoinositide phosphatase MTM-1 regulates apoptotic cell corpse clearance through CED-5-CED-12 in C. elegans.

artículo científico publicado en 2011

The short coiled-coil domain-containing protein UNC-69 cooperates with UNC-76 to regulate axonal outgrowth and normal presynaptic organization in Caenorhabditis elegans

artículo científico publicado en 2006

Transcriptional regulator of programmed cell death encoded by Caenorhabditis elegans gene ces-2.

artículo científico publicado en 1996

Translational Repression of C. elegans p53 by GLD-1 Regulates DNA Damage-Induced Apoptosis

Translational repression of C. elegans p53 by GLD-1 regulates DNA damage-induced apoptosis

artículo científico publicado en 2005

Two pathways converge at CED-10 to mediate actin rearrangement and corpse removal in C. elegans

artículo científico publicado en 2005

URI-1 is required for DNA stability in C. elegans

artículo científico publicado en 2006

WormQTL--public archive and analysis web portal for natural variation data in Caenorhabditis spp.

artículo científico publicado en 2012

ccz-1 mediates the digestion of apoptotic corpses in C. elegans

artículo científico publicado en 2010

eor-1 and eor-2 are required for cell-specific apoptotic death in C. elegans

artículo científico publicado en 2004

jkk-1 and mek-1 regulate body movement coordination and response to heavy metals through jnk-1 in Caenorhabditis elegans

artículo científico publicado en 2001

mProphet: automated data processing and statistical validation for large-scale SRM experiments

artículo científico publicado en 2011

miRNAs and apoptosis: RNAs to die for.

artículo científico publicado en 2006

Lista de obras de Michael Otmar Hengartner

A Steric-inhibition model for regulation of nucleotide exchange via the Dock180 family of GEFs

A conserved role for SNX9-family members in the regulation of phagosome maturation during engulfment of apoptotic cells

A dynamic physical model of cell migration, differentiation and apoptosis in Caenorhabditis elegans

A lectin-mediated resistance of higher fungi against predators and parasites.

A novel mouse model for inhibition of DOHH-mediated hypusine modification reveals a crucial function in embryonic development, proliferation and oncogenic transformation

A pathway for phagosome maturation during engulfment of apoptotic cells

A quantitative targeted proteomics approach to validate predicted microRNA targets in C. elegans

A worm rich in protein: Quantitative, differential, and global proteomics in Caenorhabditis elegans

Activation of C. elegans cell death protein CED-9 by an amino-acid substitution in a domain conserved in Bcl-2.

Advances in apoptosis research ⬇️

Alteration of the nuclear pore complex in Ca(2+)-mediated cell death.

Aminophospholipid translocase TAT-1 promotes phosphatidylserine exposure during C. elegans apoptosis.

Analysis of C. elegans intestinal gene expression and polyadenylation by fluorescence-activated nuclei sorting and 3'-end-seq

Apoptosis CED-4 is a stranger no more ⬇️

Apoptosis and the shape of death

Apoptotic cell death under hypoxia.

Biotoxicity assays for fruiting body lectins and other cytoplasmic proteins

C. elegans GLA-3 is a novel component of the MAP kinase MPK-1 signaling pathway required for germ cell survival

C. elegans RAD-5/CLK-2 defines a new DNA damage checkpoint protein

C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2.

Caenorhabditis elegans ABL-1 antagonizes p53-mediated germline apoptosis after ionizing irradiation

Caenorhabditis elegans DNA mismatch repair gene msh-2 is required for microsatellite stability and maintenance of genome integrity

Caenorhabditis elegans HUS-1 is a DNA damage checkpoint protein required for genome stability and EGL-1-mediated apoptosis

Caenorhabditis elegans N-glycan Core β-galactoside Confers Sensitivity towards Nematotoxic Fungal Galectin CGL2

Caenorhabditis elegans contains two distinct acid sphingomyelinases.

Caenorhabditis elegans gene ced-9 protects cells from programmed cell death

Candidate adaptor protein CED-6 promotes the engulfment of apoptotic cells in C. elegans.

Cell biology. Tickling macrophages, a serious business

Cell biology: divide and conquer

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

Cleaning up the mess: cell corpse clearance in Caenorhabditis elegans

Comparative analysis reveals conserved protein phosphorylation networks implicated in multiple diseases

Comparative functional analysis of the Caenorhabditis elegans and Drosophila melanogaster proteomes

Correction: Long-term C. elegans immobilization enables high resolution developmental studies in vivo

Death and more: DNA damage response pathways in the nematode C. elegans.

Death cycle and Swiss army knives ⬇️

Deficiency of FANCD2-associated nuclease KIAA1018/FAN1 sensitizes cells to interstrand crosslinking agents

Deleted in cancer 1 (DICE1) is an essential protein controlling the topology of the inner mitochondrial membrane in C. elegans

Developmental apoptosis in C. elegans: a complex CEDnario

Differential regulation of DNA damage response activation between somatic and germline cells in Caenorhabditis elegans.

Differential regulation of germ line apoptosis and germ cell differentiation by CPEB family members in C. elegans

Dimerization of the fungal defense lectin CCL2 is essential for its toxicity against nematodes.

Dock180 and ELMO1 proteins cooperate to promote evolutionarily conserved Rac-dependent cell migration

Dying to hold you

Engulfment genes cooperate with ced-3 to promote cell death in Caenorhabditis elegans

Epigenetic regulation of histone H3 serine 10 phosphorylation status by HCF-1 proteins in C. elegans and mammalian cells

Erratum: A quantitative targeted proteomics approach to validate predicted microRNA targets in C. elegans

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.

Establishing a Blueprint for CED-3-dependent Killing through Identification of Multiple Substrates for This Protease

Finding function in novel targets: C. elegans as a model organism

Functional identification of optimized RNAi triggers using a massively parallel sensor assay

Generic comparison of protein inference engines

Genetic control of programmed cell death and aging in the nematode Caenorhabditis elegans.

Genetics of apoptosis

Genome-wide RNAi identifies p53-dependent and -independent regulators of germ cell apoptosis in C. elegans

Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes.

HIF-1 antagonizes p53-mediated apoptosis through a secreted neuronal tyrosinase

How the worm removes corpses: the nematode C. elegans as a model system to study engulfment.

Identification of two signaling submodules within the CrkII/ELMO/Dock180 pathway regulating engulfment of apoptotic cells.

LEM-3 - A LEM domain containing nuclease involved in the DNA damage response in C. elegans

Long-term C. elegans immobilization enables high resolution developmental studies in vivo.

Loss of Acetylcholine Signaling Reduces Cell Clearance Deficiencies in Caenorhabditis elegans

Loss of the RhoGAP SRGP-1 promotes the clearance of dead and injured cells in Caenorhabditis elegans

MINA-1 and WAGO-4 are part of regulatory network coordinating germ cell death and RNAi in C. elegans

Methylated glycans as conserved targets of animal and fungal innate defense.

Microtubule-associated protein 1 light chain 3 alpha (LC3)-associated phagocytosis is required for the efficient clearance of dead cells

Model organisms proteomics--from holobionts to human nutrition.

Modeling the binding specificity of the RNA-binding protein GLD-1 suggests a function of coding region-located sites in translational repression

Molecular basis for galactosylation of core fucose residues in invertebrates: identification of caenorhabditis elegans N-glycan core alpha1,6-fucoside beta1,4-galactosyltransferase GALT-1 as a member of a novel glycosyltransferase family

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

NER and HR pathways act sequentially to promote UV-C-induced germ cell apoptosis in Caenorhabditis elegans ⬇️

Natural Genetic Variation Differentially Affects the Proteome and Transcriptome in Caenorhabditis elegans.

Natural Genetic Variation Influences Protein Abundances in C. elegans Developmental Signalling Pathways.

Nematotoxicity of Marasmius oreades agglutinin (MOA) depends on glycolipid binding and cysteine protease activity.

No death without life: vital functions of apoptotic effectors

Nonapoptotic Role for Apaf-1 in the DNA Damage Checkpoint

Nonapoptotic role for Apaf-1 in the DNA damage checkpoint

PH domain of ELMO functions in trans to regulate Rac activation via Dock180