Lista de obras - Stephen Elledge - Dominio Público Uruguay

A DNA Damage Response Screen Identifies RHINO, a 9-1-1 and TopBP1 Interacting Protein Required for ATR Signaling ⬇️

artículo científico publicado el 10 de junio de 2011

A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis

artículo científico publicado en 2012

A genetic screen for candidate tumor suppressors identifies REST

artículo científico publicado en 2005

A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair

artículo científico publicado en 2010

A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability

artículo científico publicado en 2010

A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene

artículo científico publicado en 2009

A genome-wide camptothecin sensitivity screen identifies a mammalian MMS22L-NFKBIL2 complex required for genomic stability

artículo científico publicado en 2010

A genome-wide genetic screen for host factors required for hepatitis C virus propagation

artículo científico publicado en 2009

A glycine-specific N-degron pathway mediates the quality control of protein N-myristoylation

scientific article published on 01 July 2019

A quantitative atlas of mitotic phosphorylation

artículo científico publicado en 2008

A role for the deubiquitinating enzyme USP28 in control of the DNA-damage response

artículo científico publicado en 2006

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

artículo científico publicado en 2007

Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response

artículo científico publicado en 2007

Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities

artículo científico publicado en 2007

Autoreactivity and Exceptional CDR Plasticity (but Not Unusual Polyspecificity) Hinder Elicitation of the Anti-HIV Antibody 4E10

artículo científico publicado en 2013

Comprehensive viromewide antibody responses by systematic epitope scanning after hematopoietic cell transplantation

scientific article published on 11 June 2019

Control of ribonucleotide reductase localization through an anchoring mechanism involving Wtm1.

artículo científico publicado en 2006

DNA repair. Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1

artículo científico publicado en 2014

Distinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virus

artículo científico publicado en 2011

Exit from exit: resetting the cell cycle through Amn1 inhibition of G protein signaling

artículo científico publicado en 2003

Germline-encoded amino acid–binding motifs drive immunodominant public antibody responses

artículo científico publicado en 2023

Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair

artículo científico publicado en 2015

Human Claspin works with BRCA1 to both positively and negatively regulate cell proliferation

artículo científico publicado en 2004

IFITM3 inhibits influenza A virus infection by preventing cytosolic entry

artículo científico publicado en 2011

Identification of host proteins required for HIV infection through a functional genomic screen

artículo científico publicado en 2008

Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair

artículo científico publicado en 2007

Integrated proteogenetic analysis reveals the landscape of a mitochondrial-autophagosome synapse during PARK2-dependent mitophagy

artículo científico publicado en 2019

Interspecies analysis of MYC targets identifies tRNA synthetases as mediators of growth and survival in MYC-overexpressing cells

scientific article published on 01 July 2019

MDC1 is a mediator of the mammalian DNA damage checkpoint

artículo científico publicado en 2003

Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair

artículo científico publicado en 2009

Measles virus infection diminishes preexisting antibodies that offer protection from other pathogens

scientific article published on 01 November 2019

Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases

artículo científico publicado en 2004

Multiple tumor suppressor pathways negatively regulate telomerase

artículo científico publicado en 2003

NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint control

artículo científico publicado en 2009

Ontogeny of recognition specificity and functionality for the broadly neutralizing anti-HIV antibody 4E10

artículo científico publicado en 2014

Origins of lymphatic and distant metastases in human colorectal cancer.

artículo científico publicado en 2017

Polyubiquitinated PCNA Recruits the ZRANB3 Translocase to Maintain Genomic Integrity after Replication Stress ⬇️

artículo científico publicado el 14 de junio de 2012

Proliferating cell nuclear antigen (PCNA)-associated KIAA0101/PAF15 protein is a cell cycle-regulated anaphase-promoting complex/cyclosome substrate ⬇️

artículo científico publicado el 31 de mayo de 2011

Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin

artículo científico publicado en 2002

Replication protein A-mediated recruitment and activation of Rad17 complexes ⬇️

artículo científico publicado el 6 de noviembre de 2003

SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase

artículo científico publicado en 2003

Second-generation shRNA libraries covering the mouse and human genomes

artículo científico publicado en 2005

Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

artículo científico publicado en 2003

Structural basis for antibody inhibition of flavivirus NS1-triggered endothelial dysfunction

artículo científico publicado en 2021

Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

artículo científico publicado en 2002

Structure of the FANCI-FANCD2 Complex: Insights into the Fanconi Anemia DNA Repair Pathway

artículo científico publicado en 2011

Systematic analysis and nomenclature of mammalian F-box proteins

artículo científico publicado en 2004

Systematic characterization of mutations altering protein degradation in human cancers

artículo científico publicado en 2021

Taking the brakes off telomerase

artículo científico publicado en 2015

Temporal virus serological profiling of kidney graft recipients using VirScan

scientific article published on 13 May 2019

The DNA Damage Response: Making It Safe to Play with Knives ⬇️

artículo científico publicado el 22 de octubre de 2010

The DNA damage response: ten years after

artículo científico publicado en 2007

The IFITM proteins mediate cellular resistance to influenza A H1N1 virus, West Nile virus, and dengue virus

artículo científico publicado en 2009

The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome

artículo científico publicado en 2010

The SIOD disorder protein SMARCAL1 is an RPA-interacting protein involved in replication fork restart

artículo científico publicado en 2009

The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation

artículo científico publicado en 2023

The primary mechanism of cytotoxicity of the chemotherapeutic agent CX-5461 is topoisomerase II poisoning

scientific article published on 10 February 2020

The tumor suppressor CYLD regulates entry into mitosis

artículo científico publicado en 2007

The ubiquitin-specific protease USP28 is required for MYC stability

artículo científico publicado en 2007

Tipin and Timeless form a mutually protective complex required for genotoxic stress resistance and checkpoint function

artículo científico publicado en 2006

Tissue-specificity in cancer: The rule, not the exception

artículo científico publicado en 2019

Turkey must end violent response to protests

artículo científico publicado en 2013

Viral epitope profiling of COVID-19 patients reveals cross-reactivity and correlates of severity

artículo científico publicado en 2020

WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity

artículo científico publicado en 2009

Lista de obras de Stephen Elledge

A DNA Damage Response Screen Identifies RHINO, a 9-1-1 and TopBP1 Interacting Protein Required for ATR Signaling ⬇️

A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis

A genetic screen for candidate tumor suppressors identifies REST

A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair

A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability

A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene

A genome-wide camptothecin sensitivity screen identifies a mammalian MMS22L-NFKBIL2 complex required for genomic stability

A genome-wide genetic screen for host factors required for hepatitis C virus propagation

A glycine-specific N-degron pathway mediates the quality control of protein N-myristoylation

A quantitative atlas of mitotic phosphorylation

A role for the deubiquitinating enzyme USP28 in control of the DNA-damage response

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response

Anaphase initiation is regulated by antagonistic ubiquitination and deubiquitination activities

Autoreactivity and Exceptional CDR Plasticity (but Not Unusual Polyspecificity) Hinder Elicitation of the Anti-HIV Antibody 4E10

Comprehensive viromewide antibody responses by systematic epitope scanning after hematopoietic cell transplantation

Control of ribonucleotide reductase localization through an anchoring mechanism involving Wtm1.

DNA repair. Mechanism of DNA interstrand cross-link processing by repair nuclease FAN1

Distinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virus

Exit from exit: resetting the cell cycle through Amn1 inhibition of G protein signaling

Germline-encoded amino acid–binding motifs drive immunodominant public antibody responses

Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair

Human Claspin works with BRCA1 to both positively and negatively regulate cell proliferation

IFITM3 inhibits influenza A virus infection by preventing cytosolic entry

Identification of host proteins required for HIV infection through a functional genomic screen

Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair

Integrated proteogenetic analysis reveals the landscape of a mitochondrial-autophagosome synapse during PARK2-dependent mitophagy

Interspecies analysis of MYC targets identifies tRNA synthetases as mediators of growth and survival in MYC-overexpressing cells

MDC1 is a mediator of the mammalian DNA damage checkpoint

Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair

Measles virus infection diminishes preexisting antibodies that offer protection from other pathogens

Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases

Multiple tumor suppressor pathways negatively regulate telomerase

NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint control

Ontogeny of recognition specificity and functionality for the broadly neutralizing anti-HIV antibody 4E10

Origins of lymphatic and distant metastases in human colorectal cancer.

Polyubiquitinated PCNA Recruits the ZRANB3 Translocase to Maintain Genomic Integrity after Replication Stress ⬇️

Proliferating cell nuclear antigen (PCNA)-associated KIAA0101/PAF15 protein is a cell cycle-regulated anaphase-promoting complex/cyclosome substrate ⬇️

Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin

Replication protein A-mediated recruitment and activation of Rad17 complexes ⬇️

SCFbeta-TRCP links Chk1 signaling to degradation of the Cdc25A protein phosphatase

Second-generation shRNA libraries covering the mouse and human genomes

Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

Structural basis for antibody inhibition of flavivirus NS1-triggered endothelial dysfunction

Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex

Structure of the FANCI-FANCD2 Complex: Insights into the Fanconi Anemia DNA Repair Pathway

Systematic analysis and nomenclature of mammalian F-box proteins

Systematic characterization of mutations altering protein degradation in human cancers

Taking the brakes off telomerase

Temporal virus serological profiling of kidney graft recipients using VirScan

The DNA Damage Response: Making It Safe to Play with Knives ⬇️

The DNA damage response: ten years after

The IFITM proteins mediate cellular resistance to influenza A H1N1 virus, West Nile virus, and dengue virus

The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome

The SIOD disorder protein SMARCAL1 is an RPA-interacting protein involved in replication fork restart

The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation

The primary mechanism of cytotoxicity of the chemotherapeutic agent CX-5461 is topoisomerase II poisoning

The tumor suppressor CYLD regulates entry into mitosis

The ubiquitin-specific protease USP28 is required for MYC stability

Tipin and Timeless form a mutually protective complex required for genotoxic stress resistance and checkpoint function

Tissue-specificity in cancer: The rule, not the exception

Turkey must end violent response to protests

Viral epitope profiling of COVID-19 patients reveals cross-reactivity and correlates of severity

WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity