Lista de obras - Rino Rappuoli - Dominio Público Uruguay

2. How is the economic assessment of vaccines performed today?

artículo científico publicado en 2017

3. How comprehensive can we be in the economic assessment of vaccines?

artículo científico publicado en 2017

3D imaging of the 58 kDa cell binding subunit of the Helicobacter pylori cytotoxin

artículo científico publicado en 1999

4CMenB Immunization Induces Serum Bactericidal Antibodies Against Non-Serogroup B Meningococcal Strains in Adolescents

artículo científico publicado en 2020

4CMenB vaccine induces elite cross-protective human antibodies that compete with human factor H for binding to meningococcal fHbp

artículo científico publicado en 2020

A 2020 vision for vaccines against HIV, tuberculosis and malaria

artículo científico publicado en 2011

A C terminus cysteine of diphtheria toxin B chain involved in immunotoxin cell penetration and cytotoxicity

scientific article published on 01 April 1988

A Crisis of Public Confidence in Vaccines ⬇️

artículo científico publicado el 8 de diciembre de 2010

A beta-glucan-conjugate vaccine and anti-beta-glucan antibodies are effective against murine vaginal candidiasis as assessed by a novel in vivo imaging technique

artículo científico publicado en 2009

A common conserved amino acid motif module shared by bacterial and intercellular adhesins: bacterial adherence mimicking cell cell recognition?

artículo científico publicado en 2001

A genetically detoxified derivative of heat-labile Escherichia coli enterotoxin induces neutralizing antibodies against the A subunit

artículo científico publicado en 1994

A mutant pertussis toxin molecule that lacks ADP-ribosyltransferase activity, PT-9K/129G, is an effective mucosal adjuvant for intranasally delivered proteins

artículo científico publicado en 1995

A non-living nasal influenza vaccine can induce major humoral and cellular immune responses in humans without the need for adjuvants

artículo científico publicado en 2005

A novel epigenetic regulator associated with the hypervirulent Neisseria meningitidis clonal complex 41/44.

artículo científico publicado en 2011

A novel glyco-conjugate vaccine against fungal pathogens

artículo científico publicado en 2005

A priority-setting aid for new vaccine candidates

scientific article published on March 2014

A recombinant DNA approach to the pertussis vaccine

artículo científico publicado en 1986

A second pilus type in Streptococcus pneumoniae is prevalent in emerging serotypes and mediates adhesion to host cells

artículo científico publicado en 2008

A structural overview of the Helicobacter cytotoxin

artículo científico publicado en 2000

A sweet T cell response

artículo científico publicado en 2011

A universal vaccine for serogroup B meningococcus

artículo científico publicado en 2006

ADITEC: joining forces for next-generation vaccines

artículo científico publicado en 2012

Acellular pertussis vaccine composed of genetically inactivated pertussis toxin.

artículo científico publicado en 1995

Acellular pertussis vaccines: a turning point in infant and adolescent vaccination.

artículo científico publicado en 1996

Adjuvant activity of Mycobacterium bovis BCG expressing CRM197 on the immune response induced by BCG expressing tetanus toxin fragment C.

artículo científico publicado en 2004

Adjuvant effect of non-toxic mutants of E. coli heat-labile enterotoxin following intranasal, oral and intravaginal immunization

artículo científico publicado el 1 de enero de 1998

Adjuvant is necessary for a robust immune response to a single dose of H1N1 pandemic flu vaccine in mice.

artículo científico publicado en 2009

Adjuvanted H5N1 vaccine induces early CD4+ T cell response that predicts long-term persistence of protective antibody levels

scholarly article

Adjuvanticity of the oil-in-water emulsion MF59 is independent of Nlrp3 inflammasome but requires the adaptor protein MyD88

artículo científico publicado en 2011

Adjuvanting a subunit COVID-19 vaccine to induce protective immunity

artículo científico

Aflunov®: a vaccine tailored for pre-pandemic and pandemic approaches against influenza

artículo científico publicado en 2012

Ageing and immunity: addressing immune senescence to ensure healthy ageing

artículo científico publicado en 2010

Alum adjuvanticity: unraveling a century old mystery

artículo científico publicado en 2008

An MF59-adjuvanted inactivated influenza vaccine containing A/Panama/1999 (H3N2) induced broader serological protection against heterovariant influenza virus strain A/Fujian/2002 than a subunit and a split influenza vaccine

artículo científico publicado en 2006

An analysis of the sequence variability of meningococcal fHbp, NadA and NHBA over a 50-year period in the Netherlands

artículo científico publicado en 2013

An anti-repression Fur operator upstream of the promoter is required for iron-mediated transcriptional autoregulation in Helicobacter pylori

artículo científico publicado en 2003

An audience with... Rino Rappuoli

artículo científico publicado en 2007

An efficient method to make human monoclonal antibodies from memory B cells: potent neutralization of SARS coronavirus

artículo científico publicado en 2004

An unwanted guest: Neisseria meningitidis - carriage, risk for invasive disease and the impact of vaccination with insight on Italy incidence

artículo científico publicado en 2017

Analysis of expression of CagA and VacA virulence factors in 43 strains of Helicobacter pylori reveals that clinical isolates can be divided into two major types and that CagA is not necessary for expression of the vacuolating cytotoxin

artículo científico publicado en 1995

Anatomy of Omicron BA.1 and BA.2 neutralizing antibodies in COVID-19 mRNA vaccinees

artículo científico publicado en 2022

Antibodies to influenza nucleoprotein cross-react with human hypocretin receptor 2.

artículo científico publicado en 2015

Antibody to genome-derived neisserial antigen 2132, a Neisseria meningitidis candidate vaccine, confers protection against bacteremia in the absence of complement-mediated bactericidal activity

artículo científico publicado en 2003

Antibody-dependent macrophage-mediated activity against Helicobacter pylori in the absence of complement

artículo científico publicado en 2002

Anticipating crisis: towards a pandemic flu vaccination strategy through alignment of public health and industrial policy

artículo científico publicado en 2005

Antigenic recognition of pertussis and cholera toxin by the same antipeptide antibodies

scientific article published on 01 January 1986

Antimicrobial resistance and the role of vaccines

article published in the Proceedings of the National Academy of Sciences of the United States of America

Application of microbial genomic science to advanced therapeutics

artículo científico publicado en 2005

Are serological responses to acellular pertussis antigens sufficient criteria to ensure that new combination vaccines are effective for prevention of disease?

artículo científico publicado el 1 de enero de 1997

Auto ADP-ribosylation of NarE, a Neisseria meningitidis ADP-ribosyltransferase, regulates its catalytic activities

artículo científico publicado en 2013

Auto-Assembling Detoxified Staphylococcus aureus Alpha-Hemolysin Mimicking the Wild-Type Cytolytic Toxin

artículo científico publicado en 2016

Autoregulation of Helicobacter pylori Fur revealed by functional analysis of the iron-binding site

artículo científico publicado en 2002

Bacterial pathogen genomics and vaccines.

artículo científico publicado en 2002

Beta-glucan-CRM197 conjugates as candidates antifungal vaccines

artículo científico publicado en 2010

Beyond cost-effectiveness: Using systems analysis for infectious disease preparedness

artículo científico publicado en 2016

Big science for vaccine development

article

Biochemical and biological characteristics of cross-reacting material 197 (CRM197), a non-toxic mutant of diphtheria toxin: Use as a conjugation protein in vaccines and other potential clinical applications ⬇️

artículo científico publicado el 28 de junio de 2011

Biotechnology and vaccines: application of functional genomics to Neisseria meningitidis and other bacterial pathogens

artículo científico publicado en 2004

Blocking bacterial enterotoxins

artículo científico publicado en 2000

Bordetella parapertussis and Bordetella bronchiseptica contain transcriptionally silent pertussis toxin genes

artículo científico publicado en 1987

Bridging the gap: need for a data repository to support vaccine prioritization efforts

artículo científico publicado en 2015

Bridging the knowledge gaps in vaccine design

artículo científico publicado en 2007

Bringing influenza vaccines into the 21st century.

artículo científico publicado en 2013

Building an insurance against modern pandemics.

artículo científico publicado en 2010

Cell penetration of diphtheria toxin. Reduction of the interchain disulfide bridge is the rate-limiting step of translocation in the cytosol

artículo científico publicado en 1993

Cellular microbiology emerging

artículo científico publicado en 1996

Cellular pertussis vaccine containing a Bordetella pertussis strain that produces a nontoxic pertussis toxin molecule

artículo científico publicado en 1992

Changing Priorities in Vaccinology: Antibiotic Resistance Moving to the Top.

artículo científico publicado en 2018

Changing route: aerosol vaccine against tuberculosis

artículo científico publicado en 2014

Characterization and immunogenicity of the CagF protein of the cag pathogenicity island of Helicobacter pylori

artículo científico publicado en 2002

Characterization of an IS-like element from Mycobacterium tuberculosis

artículo científico publicado en 1993

Characterization of diverse subvariants of the meningococcal factor H (fH) binding protein for their ability to bind fH, to mediate serum resistance, and to induce bactericidal antibodies

artículo científico publicado en 2010

Characterization of the HspR-mediated stress response in Helicobacter pylori

artículo científico publicado en 2002

Characterization of the antibody response to pneumococcal glycoconjugates and the effect of heat-labile enterotoxin on IGg subclasses after intranasal immunization

artículo científico publicado en 2001

Chemistry of a new investigational quadrivalent meningococcal conjugate vaccine that is immunogenic at all ages

scientific article published on 18 July 2009

Chlamydia trachomatis control requires a vaccine ⬇️

artículo científico publicado el 29 de enero de 2013

Clonal success of piliated penicillin nonsusceptible pneumococci ⬇️

artículo científico publicado en 2007

Cloning of a novel pilin-like gene from Bordetella pertussis: homology to the fim2 gene

artículo científico publicado en 1988

Combination adjuvants for the induction of potent, long-lasting antibody and T-cell responses to influenza vaccine in mice.

artículo científico publicado en 2007

Combined adenovirus vector and hepatitis C virus envelope protein prime-boost regimen elicits T cell and neutralizing antibody immune responses

artículo científico publicado en 2014

Combined conjugate vaccines: enhanced immunogenicity with the N19 polyepitope as a carrier protein

artículo científico publicado en 2005

Common features of the NAD-binding and catalytic site of ADP-ribosylating toxins

artículo científico publicado en 1994

Comparative Systems Analyses Reveal Molecular Signatures of Clinically tested Vaccine Adjuvants

artículo científico publicado en 2016

Comparative genomics of Neisseria meningitidis: core genome, islands of horizontal transfer and pathogen-specific genes

article

Comparative immunogenicity and efficacy of equivalent outer membrane vesicle and glycoconjugate vaccines against nontyphoidal

article published in the Proceedings of the National Academy of Sciences of the United States of America

Compare voting systems to improve them

artículo científico publicado en 2017

Comparison of Open-Source Reverse Vaccinology Programs for Bacterial Vaccine Antigen Discovery

scholarly article by Mattia Dalsass et al published 14 February 2019 in Frontiers in Immunology

Complete Genome Sequence of Neisseria meningitidis Serogroup B Strain MC58

artículo científico publicado en 2000

Complete genome sequence and comparative genomic analysis of an emerging human pathogen, serotype V Streptococcus agalactiae

artículo científico publicado en 2002

Conformational changes in diphtheria toxoids. Analysis with monoclonal antibodies

scientific article published on 01 June 1987

Conjugates and reverse vaccinology to eliminate bacterial meningitis

artículo científico publicado en 2001

Conservation of meningococcal antigens in the genus Neisseria

artículo científico publicado en 2013

Construction of nontoxic derivatives of cholera toxin and characterization of the immunological response against the A subunit.

artículo científico publicado en 1995

Core values for vaccine evaluation

artículo científico publicado en 2016

Correction: Structure and dynamics of the pan-genome of Streptococcus pneumoniae and closely related species.

artículo científico publicado en 2011

Correlates of adjuvanticity: A review on adjuvants in licensed vaccines

article

Correlates of protection against influenza infection in humans—on the path to a universal vaccine? ⬇️

artículo científico publicado el 13 de agosto de 2013

Corrigendum: Vaccines Against Antimicrobial Resistance

artículo científico publicado en 2020

Cost effectiveness has its place, but so does common sense

artículo científico publicado en 2014

Coxsackie B4 virus infection of beta cells and natural killer cell insulitis in recent-onset type 1 diabetic patients

artículo científico publicado en 2007

CrgA is an inducible LysR-type regulator of Neisseria meningitidis, acting both as a repressor and as an activator of gene transcription

artículo científico publicado en 2005

Current Developments in New Vaccines for Adolescents ⬇️

artículo científico publicado el 1 de junio de 1997

Current approaches to developing a preventative HIV vaccine.

artículo científico publicado en 2005

Cytoskeletal alterations as a parameter for assessment of toxicity

artículo científico publicado en 1988

DNA binding of the Bordetella pertussis H1 homolog alters in vitro DNA flexibility

artículo científico publicado en 1996

DNA element of Corynebacterium diphtheriae with properties of an insertion sequence and usefulness for epidemiological studies

artículo científico publicado en 1987

DNA topology affects transcriptional regulation of the pertussis toxin gene of Bordetella pertussis in Escherichia coli and in vitro

artículo científico publicado en 1993

DNA vaccination

artículo científico publicado en 2003

Defining a protective epitope on factor H binding protein, a key meningococcal virulence factor and vaccine antigen

artículo científico publicado en 2013

Deletion of the major proteolytic site of the Helicobacter pylori cytotoxin does not influence toxin activity but favors assembly of the toxin into hexameric structures.

artículo científico publicado en 1998

Deploy vaccines to fight superbugs

artículo científico publicado en 2017

Designing the Next Generation of Vaccines for Global Public Health ⬇️

artículo científico publicado el 17 de junio de 2011

Designing vaccines for the twenty-first century society

artículo científico publicado en 2014

Detection and physical map of a omega tox+-related defective prophage in Corynebacterium diphtheriae Belfanti 1030(-)tox-.

artículo científico publicado en 1985

Detection of a vacuolating cytotoxin in stools from children with diarrhea

artículo científico publicado en 1996

Detoxification of the Helicobacter pylori cytotoxin ⬇️

artículo científico publicado el 1 de noviembre de 1997

Developing vaccines for an aging population

artículo científico

Development and clinical testing of an acellular pertussis vaccine containing genetically detoxified pertussis toxin

artículo científico publicado el 1 de febrero de 1992

Development of V2-deleted trimeric envelope vaccine candidates from human immunodeficiency virus type 1 (HIV-1) subtypes B and C.

artículo científico publicado en 2005

Development of a glycoconjugate vaccine to prevent meningitis in Africa caused by meningococcal serogroup X.

artículo científico publicado en 2013

Development of a mouse model of Helicobacter pylori infection that mimics human disease

artículo científico publicado en 1995

Development of a vaccine against serogroup B has been the main scientific challenge. Preface

artículo científico publicado en 2012

Development of an influenza virus protein array using Sortagging technology

artículo científico publicado en 2012

Development of the new acellular recombinant pertussis vaccine

scientific article published on 01 July 1994

Development of vaccines against Helicobacter pylori

artículo científico publicado en 2009

Did the inheritance of a pathogenicity island modify the virulence of Helicobacter pylori?

artículo científico publicado en 1997

Different human vaccine adjuvants promote distinct antigen-independent immunological signatures tailored to different pathogens

artículo científico publicado en 2016

Differential binding of BvgA to two classes of virulence genes of Bordetella pertussis directs promoter selectivity by RNA polymerase.

artículo científico publicado en 1996

Differential response of the bvg virulence regulon of Bordetella pertussis to MgSO4 modulation

artículo científico publicado en 1991

Diphtheria toxin and its mutant crm 197 differ in their interaction with lipids

artículo científico publicado en 1987

Dissecting human T cell responses against Bordetella species

artículo científico publicado en 1988

Distribution and genetic variability of three vaccine components in a panel of strains representative of the diversity of serogroup B meningococcus

artículo científico publicado en 2009

Dual RNA-seq of Nontypeable Haemophilus influenzae and Host Cell Transcriptomes Reveals Novel Insights into Host-Pathogen Cross Talk

artículo científico publicado en 2015

Dual control of Helicobacter pylori heat shock gene transcription by HspR and HrcA.

artículo científico publicado en 2004

Editorial overview: Preventive and therapeutic vaccines: Vaccination against viral disease - current advances and challenges

artículo científico publicado en 2017

Editorial overview: Vaccines 2020

artículo científico publicado en 2020

Editorial overview: Vaccines: novel technologies for vaccine development

artículo científico publicado en 2016

Editorial: A Global Perspective on Vaccines: Priorities, Challenges and Online Information.

artículo científico publicado en 2019

Editorial: Advanced Immunization Technologies for Next Generation Vaccines

scientific article published on 06 May 2020

Editorial: Reverse Vaccinology

scientific article published on 03 December 2019

Effect of Neisseria meningitidis fur mutations on global control of gene transcription

artículo científico publicado en 2006

Effect of heparin binding on Helicobacter pylori resistance to serum

artículo científico publicado en 2004

Effects of the insertion of a nonapeptide from murine IL-1beta on the immunogenicity of carrier proteins delivered by live attenuated Salmonella

artículo científico publicado en 1998

Efficacy of vaccination with different combinations of MF59-adjuvanted and nonadjuvanted seasonal and pandemic influenza vaccines against pandemic H1N1 (2009) influenza virus infection in ferrets

artículo científico publicado en 2011

Efficacy, immunogenicity, and safety of a parenteral vaccine against Helicobacter pylori in healthy volunteers challenged with a Cag-positive strain: a randomised, placebo-controlled phase 1/2 study

scientific article published on 02 July 2018

Efficient production of heat-labile enterotoxin mutant proteins by overexpression of dsbA in a degP-deficient Escherichia coli strain.

artículo científico publicado en 1997

Emerging experience with meningococcal serogroup B protein vaccines

artículo científico publicado en 2017

Emerging infectious diseases: A proactive approach

artículo científico publicado en 2017

Emerging vaccine informatics

artículo científico publicado en 2010

Enhancement of protective efficacy following intranasal immunization with vaccine plus a nontoxic LTK63 mutant delivered with nanoparticles

artículo científico publicado en 2002

Environmental regulation of virulence factors in Bordetella species

artículo científico publicado en 1993

Epitope mapping of a bactericidal monoclonal antibody against the factor H binding protein of Neisseria meningitidis.

artículo científico publicado en 2008

Erratum for Baddal et al., Dual RNA-seq of Nontypeable Haemophilus influenzae and Host Cell Transcriptomes Reveals Novel Insights into Host-Pathogen Cross Talk

artículo científico publicado en 2016

Escherichia coli heat-labile enterotoxin promotes protective Th17 responses against infection by driving innate IL-1 and IL-23 production

artículo científico publicado en 2011

Escherichia coli: great diversity around a common core

artículo científico publicado en 2012

European Commission COST/STD Initiative. Report of the expert panel VIII. New vaccines, especially new combined vaccines

artículo científico publicado en 1996

Evaluation of a Group A Streptococcus synthetic oligosaccharide as vaccine candidate

artículo científico publicado en 2010

Evaluation of the recombinant 38-kilodalton antigen of Mycobacterium tuberculosis as a potential immunodiagnostic reagent

artículo científico publicado en 1997

Evolution of functional polymorphism in the gene coding for the Helicobacter pylori cytotoxin

artículo científico publicado en 2002

Experimental model of Helicobacter pylori infection

artículo científico publicado en 1998

Expression and immunological properties of the five subunits of pertussis toxin

artículo científico publicado en 1987

Expression and selective up-regulation of toxin-related mono ADP-ribosyltransferases by pathogen-associated molecular patterns in alveolar epithelial cells

artículo científico publicado en 2007

Expression of factor H binding protein in meningococcal strains can vary at least 15-fold and is genetically determined

artículo científico publicado en 2016

Expression of fragment C of tetanus toxin fused to a carboxyl-terminal fragment of diphtheria toxin in Salmonella typhi CVD 908 vaccine strain

artículo científico publicado en 1995

Factor H-binding protein, a unique meningococcal vaccine antigen

artículo científico publicado en 2008

Families of bacterial signal-transducing proteins

artículo científico publicado en 1989

FdeC, a Novel Broadly Conserved Escherichia coli Adhesin Eliciting Protection against Urinary Tract Infections

artículo científico publicado en 2012

Finding epitopes with computers

artículo científico publicado en 2013

Formaldehyde treatment of proteins can constrain presentation to T cells by limiting antigen processing

artículo científico publicado en 1994

Four-component Meningococcal Serogroup B Vaccine Induces Antibodies With Bactericidal Activity Against Diverse Outbreak Strains in Adolescents

scientific article published on 13 October 2020

From Pasteur to genomics: progress and challenges in infectious diseases

artículo científico publicado en 2004

From empiricism to rational design: a personal perspective of the evolution of vaccine development

artículo científico publicado en 2014

From pioneers to marketeers

artículo científico publicado en 2000

Functional analysis of the Helicobacter pylori principal sigma subunit of RNA polymerase reveals that the spacer region is important for efficient transcription

artículo científico publicado en 1998

Functional analysis of the pertussis toxin promoter

artículo científico publicado el 1 de septiembre de 1992

Fur functions as an activator and as a repressor of putative virulence genes in Neisseria meningitidis

artículo científico publicado en 2004

Further analysis of the sequence of the S1 subunit of pertussis toxin

artículo científico publicado en 1991

Future Challenges for Vaccinologists

artículo científico publicado en 2016

GITR contributes to the systemic adjuvanticity of the Escherichia coli heat-labile enterotoxin

artículo científico publicado en 2010

GNA33 from Neisseria meningitidis serogroup B encodes a membrane-bound lytic transglycosylase (MltA).

artículo científico publicado en 2002

GNA33 of Neisseria meningitidis is a lipoprotein required for cell separation, membrane architecture, and virulence.

artículo científico publicado en 2004

Generating memory with vaccination

artículo científico publicado en 2009

Generation of human monoclonal antibodies that confer protection against pertussis toxin ⬇️

artículo científico publicado el 1 de marzo de 1992

Genetic Meningococcal Antigen Typing System (gMATS): A genotyping tool that predicts 4CMenB strain coverage worldwide

artículo científico publicado en 2019

Genetic detoxification of bacterial toxins

artículo científico publicado en 2003

Genetic detoxification of bacterial toxins: a new approach to vaccine development

artículo científico publicado en 1995

Genetically derived toxoids for use as vaccines and adjuvants

artículo científico publicado en 1999

Genetically detoxified pertussis toxin induces Th1/Th17 immune response through MAPKs and IL-10-dependent mechanisms.

artículo científico publicado en 2009

Genetics of pertussis toxin

artículo científico

Genome Analysis Reveals Pili in Group B Streptococcus

artículo científico publicado en 2005

Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: implications for the microbial "pan-genome"

artículo científico publicado en 2005

Genome and infectious diseases

artículo científico publicado en 2005

Genome sequencing of disease and carriage isolates of nontypeable Haemophilus influenzae identifies discrete population structure

artículo científico publicado en 2014

Genome-based vaccine development: a short cut for the future

artículo científico publicado en 2009

Genome-derived vaccines

artículo científico publicado en 2004

Genome‑based vaccine development: A short cut for the future ⬇️

artículo científico publicado el 1 de mayo de 2008

Genomics of ecology and industrial microbiology

artículo científico publicado en 2009

Glycoconjugate vaccines: Principles and mechanisms

scientific article published on 01 August 2018

Group B Streptococcus crosses human epithelial cells by a paracellular route

artículo científico publicado en 2005

Group B Streptococcus: global incidence and vaccine development

artículo científico publicado en 2006

Growth of Helicobacter pylori in media containing cyclodextrins

artículo científico publicado en 1993

Growth phase-dependent regulation of target gene promoters for binding of the essential orphan response regulator HP1043 of Helicobacter pylori

artículo científico publicado en 2002

H1N1: can a pandemic cycle be broken?

artículo científico publicado en 2010

HIV-1 tat promotes integrin-mediated HIV transmission to dendritic cells by binding Env spikes and competes neutralization by anti-HIV antibodies

artículo científico publicado en 2012

HadA is an atypical new multifunctional trimeric coiled-coil adhesin of Haemophilus influenzae biogroup aegyptius, which promotes entry into host cells

artículo científico publicado en 2009

Heat-labile enterotoxin of Escherichia coli and its site-directed mutant LTK63 enhance the proliferative and cytotoxic T-cell responses to intranasally co-immunized synthetic peptides

artículo científico publicado en 1999

Helicobacter pylori CagA: From Pathogenic Mechanisms to Its Use as an Anti-Cancer Vaccine

artículo científico publicado en 2013

Helicobacter pylori VacA cytotoxin associated with the bacteria increases epithelial permeability independently of its vacuolating activity

artículo científico publicado en 1999

Helicobacter pylori cytotoxin-associated gene A (CagA) subverts the apoptosis-stimulating protein of p53 (ASPP2) tumor suppressor pathway of the host

artículo científico publicado en 2011

Helicobacter pylori cytotoxin: importance of native conformation for induction of neutralizing antibodies

artículo científico publicado en 1995

Helicobacter pylori induced interleukin-8 expression in gastric epithelial cells is associated with CagA positive phenotype

artículo científico publicado en 1995

Helicobacter pylori infection negatively influences pregnancy outcome in a mouse model

artículo científico publicado en 2004

Helicobacter pylori interactions with host serum and extracellular matrix proteins: potential role in the infectious process

artículo científico publicado en 2002

Helicobacter pylori neutrophil-activating protein stimulates tissue factor and plasminogen activator inhibitor-2 production by human blood mononuclear cells

scientific article published on 23 February 2001

Helicobacter pylori virulence and genetic geography ⬇️

artículo científico publicado en 1999

Helicobacter pylori-specific CD4+ T-cell clones from peripheral blood and gastric biopsies

artículo científico publicado en 1995

Helicobacter pylori: after the genomes, back to biology

artículo científico publicado en 2003

Helicobacter pylori: molecular evolution of a bacterial quasi-species

artículo científico publicado en 1998

Hemagglutination inhibition antibody titers as a correlate of protection for inactivated influenza vaccines in children

artículo científico publicado en 2011

Histidine 21 is at the NAD+ binding site of diphtheria toxin

artículo científico publicado en 1989

Human T cell clones define S1 subunit as the most immunogenic moiety of pertussis toxin and determine its epitope map.

artículo científico publicado en 1989

Human T cell immunity against Bordetella pertussis analyzed at clonal level

artículo científico publicado el 1 de enero de 1991

Human T lymphocyte clones specific for "Bordetella pertussis"

scientific article published on 01 January 1986

Human T-cell immunity against Bordetella pertussis analyzed at clonal level

artículo científico publicado en 1988

Human circulating influenza-CD4 + ICOS1 + IL-21 + T cells expand after vaccination, exert helper function, and predict antibody responses ⬇️

artículo científico publicado el 12 de agosto de 2013

Human heat shock protein (Hsp) 90 interferes with Neisseria meningitidis adhesin A (NadA)-mediated adhesion and invasion

artículo científico publicado en 2011

Human monoclonal antibodies for discovery, therapy, and vaccine acceleration

scientific article published on 23 August 2019

Human papillomavirus E2 protein: a potential key regulator of viral cell pathogenesis ⬇️

artículo científico publicado el 1 de julio de 2012

Hydrophobic photolabelling of pertussis toxin subunits interacting with lipids

artículo científico publicado en 1986

IL-1 stimulates a diverging signaling pathway in EL4 6.1 thymoma cells. IL-2 release, but not IL-2 receptor expression, is sensitive to pertussis toxin ⬇️

artículo científico publicado el 1 de julio de 1995

INNAMORA, a European Workshop focussed on the mechanisms of innate immunity in pathogen-host interaction and their exploitation in novel mucosal immunisation strategies

scientific article published on 01 June 2003

Identification of Neisseria meningitidis nonlipopolysaccharide ligands for class A macrophage scavenger receptor by using a novel assay

artículo científico

Identification of a 35-Kilodalton Protein Containing B- and T-Cell Epitopes

scientific article published in 2006

Identification of a 35-kilodalton Mycobacterium tuberculosis protein containing B- and T-cell epitopes

artículo científico publicado en 1990

Identification of a new OmpA-like protein in Neisseria gonorrhoeae involved in the binding to human epithelial cells and in vivo colonization

artículo científico publicado en 2007

Identification of a universal Group B streptococcus vaccine by multiple genome screen

artículo científico publicado en 2005

Identification of an iron-sulfur cluster that modulates the enzymatic activity in NarE, a Neisseria meningitidis ADP-ribosyltransferase

artículo científico publicado en 2009

Identification of iron-activated and -repressed Fur-dependent genes by transcriptome analysis of Neisseria meningitidis group B.

artículo científico publicado en 2003

Identification of neutralizing human monoclonal antibodies from Italian Covid-19 convalescent patients

artículo científico publicado en 2020

Identification of protective and broadly conserved vaccine antigens from the genome of extraintestinal pathogenic Escherichia coli

artículo científico publicado en 2010

Identification of subregions of Bordetella pertussis filamentous hemagglutinin that stimulate human T-cell responses ⬇️

artículo científico publicado el 1 de septiembre de 1991

IgA-dependent cell-mediated activity against enteropathogenic bacteria: distribution, specificity, and characterization of the effector cells

artículo científico publicado en 1984

Immune response to SARS-CoV-2 Omicron variant in patients and vaccinees following homologous and heterologous vaccinations

artículo científico publicado en 2022

Immunisation against meningococcus B

artículo científico publicado en 2013

Immunization with the Chlamydia trachomatis major outer membrane protein, using adjuvants developed for human vaccines, can induce partial protection in a mouse model against a genital challenge

artículo científico publicado en 2005

Immunobiology of Helicobacter pylori infection ⬇️

artículo científico publicado el 1 de agosto de 1997

Immunohistochemical study of lymphocyte populations infiltrating the gastric mucosa of beagle dogs experimentally infected with Helicobacter pylori

artículo científico publicado en 2000

Immunological fingerprint of 4CMenB recombinant antigens via protein microarray reveals key immunosignatures correlating with bactericidal activity

artículo científico publicado en 2020

Improving accountability in vaccine decision-making

artículo científico publicado en 2017

Improving influenza vaccines ⬇️

artículo científico publicado el 1 de agosto de 2012

In silico identification of novel bacterial ADP-ribosyltransferases

artículo científico publicado en 2004

In vitro analysis of protein-operator interactions of the NikR and fur metal-responsive regulators of coregulated genes in Helicobacter pylori

artículo científico publicado en 2005

In vitro selection of high affinity HspR-binding sites within the genome of Helicobacter pylori

scientific article published on 01 January 2002

In vivo dissection of the Helicobacter pylori Fur regulatory circuit by genome-wide location analysis

artículo científico publicado en 2006

Inactivated and adjuvanted influenza vaccines.

artículo científico publicado en 2015

Induction of antigen-specific antibodies in vaginal secretions by using a nontoxic mutant of heat-labile enterotoxin as a mucosal adjuvant

artículo científico publicado en 1996

Induction of interleukin-8 secretion from gastric epithelial cells by a cagA negative isogenic mutant of Helicobacter pylori

artículo científico publicado en 1995

Induction of neutralizing antibodies against diphtheria toxin by priming with recombinant Mycobacterium bovis BCG expressing CRM(197), a mutant diphtheria toxin.

artículo científico publicado en 2001

Induction of protective serum meningococcal bactericidal and diphtheria-neutralizing antibodies and mucosal immunoglobulin A in volunteers by nasal insufflations of the Neisseria meningitidis serogroup C polysaccharide-CRM197 conjugate vaccine mixed

artículo científico publicado en 2005

Influence of Statins on Influenza Vaccine Response in Elderly Individuals

artículo científico publicado en 2015

Influence of sequence variability on bactericidal activity sera induced by Factor H binding protein variant 1.1.

scientific article published on 03 December 2010

Influence of serogroup B meningococcal vaccine antigens on growth and survival of the meningococcus in vitro and in ex vivo and in vivo models of infection

scientific article published on 10 January 2010

Influenza vaccine immunology ⬇️

artículo científico publicado el 1 de enero de 2011

Influenza: Options to Improve Pandemic Preparation ⬇️

artículo científico publicado el 22 de junio de 2012

Inhibiting neuraminidase can make the difference

scientific article published on 25 January 2019

Innate imprinting by the modified heat-labile toxin of Escherichia coli (LTK63) provides generic protection against lung infectious disease

artículo científico publicado en 2004

Inner Workings: 1885, the first rabies vaccination in humans

artículo científico publicado en 2014

Inside sensors detecting outside pathogens

scientific article published on 01 November 2004

Interaction of the pertussis toxin peptide containing residues 30-42 with DR1 and the T-cell receptors of 12 human T-cell clones ⬇️

artículo científico publicado el 1 de abril de 1992

Interlaboratory standardization of the sandwich enzyme-linked immunosorbent assay designed for MATS, a rapid, reproducible method for estimating the strain coverage of investigational vaccines

artículo científico publicado en 2012

Intranasal immunization with SAG1 and nontoxic mutant heat-labile enterotoxins protects mice against Toxoplasma gondii

artículo científico publicado en 2001

Intranasal immunization with genetically detoxified diphtheria toxin induces T cell responses in humans: enhancement of Th2 responses and toxin-neutralizing antibodies by formulation with chitosan

artículo científico publicado en 2004

Introduction of unmarked mutations in the Helicobacter pylori vacA gene with a sucrose sensitivity marker

artículo científico publicado en 1997

Introduction to the supplement

artículo científico publicado en 2015

Introduction to the vaccine supplement

artículo científico publicado en 2016

Introduction: Addressing the challenge of group B streptococcal disease

artículo científico publicado en 2013

Invariant NKT cells sustain specific B cell responses and memory

artículo científico publicado en 2007

Investigation on the effect of immune selection on resistance to bactericidal antibodies to group B meningococci in vitro

artículo científico publicado en 2009

Involvement of the intrinsic and extrinsic cell-death pathways in the induction of apoptosis of mature lymphocytes by the Escherichia coli heat-labile enterotoxin

artículo científico publicado en 2009

Isogenic mutants of the cag pathogenicity island of Helicobacter pylori in the mouse model of infection: effects on colonization efficiency

artículo científico publicado en 2002

Italy must invest more in science and technology

scientific article published on 01 April 2008

LTK63 and LTR72, two mucosal adjuvants ready for clinical trials

artículo científico publicado en 2000

Lack of Interference with Immunogenicity of a Chimeric Alphavirus Replicon Particle-Based Influenza Vaccine by Preexisting Antivector Immunity ⬇️

artículo científico publicado el 23 de mayo de 2012

Learning from the 2009 H1N1 pandemic: prospects for more broadly effective influenza vaccines ⬇️

artículo científico publicado el 23 de marzo de 2011

Lessons from Reverse Vaccinology for viral vaccine design

artículo científico

Living dangerously: how Helicobacter pylori survives in the human stomach

artículo científico publicado en 2001

Long noncoding RNAs are involved in multiple immunological pathways in response to vaccination

scientific article published on 09 August 2019

Long-term solutions for the problem of vaccine shortages

Lymphokine secretion and cytotoxic activity of human CD4+ T-cell clones against Bordetella pertussis ⬇️

artículo científico publicado el 1 de octubre de 1991

LytM proteins play a crucial role in cell separation, outer membrane composition, and pathogenesis in nontypeable Haemophilus influenzae.

artículo científico publicado en 2015

MF59 Adjuvant Enhances Diversity and Affinity of Antibody-Mediated Immune Response to Pandemic Influenza Vaccines ⬇️

artículo científico publicado el 1 de junio de 2011

MF59 adjuvant: the best insurance against influenza strain diversity ⬇️

artículo científico publicado el 1 de abril de 2011

MHC class I-restricted cytotoxic lymphocyte responses induced by enterotoxin-based mucosal adjuvants

article

Measuring antigen-specific bactericidal responses to a multicomponent vaccine against serogroup B meningococcus

artículo científico publicado en 2010

Medicine. The intangible value of vaccination

scientific article published on 01 August 2002

Meningococcal B Vaccine during a University Outbreak

artículo científico publicado en 2016

Meningococcal B vaccine (4CMenB): the journey from research to real world experience

scientific article published on 05 December 2018

Meningococcal factor H-binding protein as immune evasion factor and vaccine antigen

scientific article published on 16 April 2020

Metronidazole resistance in Helicobacter pylori

scientific article published on 01 April 1999

Microbial genomes and vaccine design: refinements to the classical reverse vaccinology approach

artículo científico publicado en 2006

Microbial pathogenesis--an interdisciplinary point of view

scientific article published on 01 April 1995

Microbiology in the post-genomic era.

artículo científico publicado en 2008

Modulation of immune response to group C meningococcal conjugate vaccine given intranasally to mice together with the LTK63 mucosal adjuvant and the trimethyl chitosan delivery system

artículo científico publicado en 2004

Modulation of the immune response to the severe acute respiratory syndrome spike glycoprotein by gene-based and inactivated virus immunization

artículo científico publicado en 2005

Molecular approaches for safer and stronger vaccines

artículo científico publicado en 1999

Molecular architecture of Streptococcus pneumoniae TIGR4 pili

artículo científico publicado en 2009

Molecular epidemiology of the 1984-1986 outbreak of diphtheria in Sweden

artículo científico publicado en 1988

Molecular mechanisms of complement evasion: learning from staphylococci and meningococci

artículo científico publicado en 2010

Mu-like Prophage in serogroup B Neisseria meningitidis coding for surface-exposed antigens

artículo científico publicado en 2001

Mucosal administration of Ag85B-ESAT-6 protects against infection with Mycobacterium tuberculosis and boosts prior bacillus Calmette-Guerin immunity

artículo científico publicado en 2006

Mucosal delivery of the human immunodeficiency virus-1 Tat protein in mice elicits systemic neutralizing antibodies, cytotoxic T lymphocytes and mucosal IgA.

artículo científico publicado en 2003

Mucosal delivery of vaccines

artículo científico publicado en 1999

Mucosal immunogenicity of genetically detoxified derivatives of heat labile toxin from Escherichia coli ⬇️

artículo científico publicado el 1 de julio de 1998

Mucosal vaccination against serogroup B meningococci: induction of bactericidal antibodies and cellular immunity following intranasal immunization with NadA of Neisseria meningitidis and mutants of Escherichia coli heat-labile enterotoxin

artículo científico publicado en 2004

Multicomponent meningococcal serogroup B vaccination elicits cross-reactive immunity in infants against genetically diverse serogroup C, W and Y invasive disease isolates

scientific article published on 06 October 2020

Multicriteria decision analysis and core values for enhancing vaccine-related decision-making

artículo científico publicado en 2016

Mutants of Escherichia coli heat-labile toxin lacking ADP-ribosyltransferase activity act as nontoxic, mucosal adjuvants

artículo científico publicado en 1995

Mutants of the Escherichia coli heat-labile enterotoxin as safe and strong adjuvants for intranasal delivery of vaccines

artículo científico publicado en 2003

Mutations in the A subunit affect yield, stability, and protease sensitivity of nontoxic derivatives of heat-labile enterotoxin

artículo científico publicado en 1996

N19 polyepitope as a carrier for enhanced immunogenicity and protective efficacy of meningococcal conjugate vaccines

artículo científico publicado en 2004

NadA diversity and carriage in Neisseria meningitidis

artículo científico publicado en 2004

NadA, a novel vaccine candidate of Neisseria meningitidis

artículo científico publicado en 2002

NarE: a novel ADP-ribosyltransferase from Neisseria meningitidis

artículo científico publicado en 2003

Neisseria adhesin A variation and revised nomenclature scheme

artículo científico publicado en 2014

Neisseria gonorrhoeae PIII has a role on NG1873 outer membrane localization and is involved in bacterial adhesion to human cervical and urethral epithelial cells

artículo científico publicado en 2013

Neisseria meningitidis App, a new adhesin with autocatalytic serine protease activity

artículo científico publicado en 2003

Neisseria meningitidis GNA2132, a heparin-binding protein that induces protective immunity in humans

artículo científico publicado en 2010

Neisseria meningitidis NadA is a new invasin which promotes bacterial adhesion to and penetration into human epithelial cells.

artículo científico publicado en 2005

Neisseria meningitidis NalP cleaves human complement C3, facilitating degradation of C3b and survival in human serum

artículo científico publicado en 2013

Neisseria meningitidis NhhA is a multifunctional trimeric autotransporter adhesin

artículo científico publicado en 2006

Neisseria meningitidis group B correlates of protection and assay standardization--international meeting report Emory University, Atlanta, Georgia, United States, 16-17 March 2005.

artículo científico publicado en 2006

Neisseria meningitidis is structured in clades associated with restriction modification systems that modulate homologous recombination

artículo científico publicado en 2011

Neisseria meningitidis: pathogenesis and immunity

artículo científico publicado en 2014

Neutrophil-activating protein (HP-NAP) versus ferritin (Pfr): comparison of synthesis in Helicobacter pylori

artículo científico publicado en 2001

New adjuvants for human vaccines

artículo científico publicado en 2010

New strategies for the prevention and treatment of Helicobacter pylori infection

artículo científico publicado en 2002

Ng-MIP, a surface-exposed lipoprotein of Neisseria gonorrhoeae, has a peptidyl-prolyl cis/trans isomerase (PPIase) activity and is involved in persistence in macrophages

artículo científico publicado en 2005

Nonviral delivery of self-amplifying RNA vaccines ⬇️

artículo científico publicado el 20 de agosto de 2012

Novel adjuvant Alum-TLR7 significantly potentiates immune response to glycoconjugate vaccines

artículo científico publicado en 2016

Novel approaches to pediatric vaccine delivery

artículo científico publicado en 2006

Novel approaches to vaccine delivery

artículo científico publicado en 2004

Novel meningococcal 4CMenB vaccine antigens - prevalence and polymorphisms of the encoding genes in Neisseria gonorrhoeae

artículo científico publicado en 2012

Oil-in-Water Emulsion MF59 Increases Germinal Center B Cell Differentiation and Persistence in Response to Vaccination

artículo científico publicado en 2015

Oligomeric and subunit structure of the Helicobacter pylori vacuolating cytotoxin

artículo científico publicado en 1996

On the Cellular Mechanism of Action of Diphtheria Toxin

On the mechanisms of conjugate vaccines

artículo científico publicado en 2018

On the membrane translocation of diphtheria toxin: at low pH the toxin induces ion channels on cells.

artículo científico publicado en 1988

One Dose of Staphylococcus aureus 4C-Staph Vaccine Formulated with a Novel TLR7-Dependent Adjuvant Rapidly Protects Mice through Antibodies, Effector CD4+ T Cells, and IL-17A.

artículo científico publicado en 2016

One dose of an MF59-adjuvanted pandemic A/H1N1 vaccine recruits pre-existing immune memory and induces the rapid rise of neutralizing antibodies

artículo científico publicado en 2012

Opinion: Cell entry machines: a common theme in nature?

artículo científico publicado en 2005

Optimized fluorescent labeling to identify memory B cells specific for Neisseria meningitidis serogroup B vaccine antigens ex vivo

artículo científico publicado en 2013

Oral spray immunization may be an alternative to intranasal vaccine delivery to induce systemic antibodies but not nasal mucosal or cellular immunity

artículo científico publicado en 2006

Pangenomic Reverse Vaccinology

article published in 2009

Pathogenesis of Helicobacter pylori and perspectives of vaccine development against an emerging pathogen.

artículo científico publicado en 1994

Perspectives on vaccine development for the elderly

artículo científico

Pertussis toxin export requires accessory genes located downstream from the pertussis toxin operon

artículo científico publicado en 1993

Pertussis toxin interferes with superantigen-induced deletion of peripheral T cells without affecting T cell activation in vivo. Inhibition of deletion and associated programmed cell death depends on ADP-ribosyltransferase activity

scientific article published on 01 May 1994

Pertussis toxin potentiates Th1 and Th2 responses to co-injected antigen: adjuvant action is associated with enhanced regulatory cytokine production and expression of the co-stimulatory molecules B7-1, B7-2 and CD28.

artículo científico publicado en 1998

Pertussis toxin promoter sequences involved in modulation

artículo científico publicado en 1989

Phagocyte subsets and lymphocyte clonal deletion behind ineffective immune response to Staphylococcus aureus

artículo científico

Phase I clinical trial of an acellular pertussis vaccine composed of genetically detoxified pertussis toxin combined with FHA and 69 kDa ⬇️

artículo científico publicado el 1 de octubre de 1991

Phase variants of Bordetella bronchiseptica arise by spontaneous deletions in the vir locus

artículo científico publicado en 1989

Phylogeny of the SARS coronavirus

artículo científico publicado en 2003

Physical map of the chromosomal region of Corynebacterium diphtheriae containing corynephage attachment sites attB1 and attB2 ⬇️

artículo científico publicado el 1 de abril de 1984

Physicochemical characterisation of glycoconjugate vaccines for prevention of meningococcal diseases

artículo científico publicado en 2008

Pili in gram-positive pathogens

artículo científico publicado en 2006

Pilus operon evolution in Streptococcus pneumoniae is driven by positive selection and recombination

artículo científico publicado en 2008

Pneumococcal pili are composed of protofilaments exposing adhesive clusters of Rrg A

artículo científico publicado en 2008

Positive regulation of pertussis toxin expression

artículo científico publicado en 1988

Positive transcriptional feedback at the bvg locus controls expression of virulence factors in Bordetella pertussis

artículo científico publicado en 1990

Positive transcriptional feedback at the bvg locus controls expression of virulence factors in Bordetella pertussis

scholarly article

Post-genomic vaccine development

artículo científico publicado en 2006

Post-hoc analysis from phase III trials of human papillomavirus vaccines: considerations on impact on non-vaccine types

scientific article published on 04 March 2019

Preclinical evaluation of group B Neisseria meningitidis and Escherichia coli K92 capsular polysaccharide-protein conjugate vaccines in juvenile rhesus monkeys

artículo científico publicado en 1997

Predicted strain coverage of a meningococcal multicomponent vaccine (4CMenB) in Europe: a qualitative and quantitative assessment

artículo científico publicado en 2013

Preparation, characterization and immunogenicity of HIV-1 related high-mannose oligosaccharides-CRM197 glycoconjugates

artículo científico publicado en 2010

Prevalence and genetic diversity of candidate vaccine antigens among invasive Neisseria meningitidis isolates in the United States

scientific article published on 13 May 2011

Prevalence and sequence variations of the genes encoding the five antigens included in the novel 5CVMB vaccine covering group B meningococcal disease

scientific article published on 20 January 2009

Preventing Newborn Infection with Maternal Immunization ⬇️

artículo científico publicado el 24 de julio de 2013

Prevention and control of meningococcal outbreaks: The emerging role of serogroup B meningococcal vaccines

artículo científico

Previously unrecognized vaccine candidates against group B meningococcus identified by DNA microarrays

artículo científico publicado en 2002

Priming to heat shock proteins in infants vaccinated against pertussis.

artículo científico publicado en 1993

Production and characterization of high titre rabbit antigonococcal R-type lipopolysaccharide serum

scientific article published on 01 July 1982

Production and characterization of monoclonal antibodies (Mabs) specifically reactive with the different subunits of toxin from "Bordetella pertussis"

artículo científico publicado en 1986

Progress towards the development of new vaccines against whooping cough

artículo científico publicado el 1 de enero de 1992

Promoter of the pertussis toxin operon and production of pertussis toxin

artículo científico publicado en 1987

Properties of pertussis toxin mutant PT-9K/129G after formaldehyde treatment ⬇️

artículo científico publicado el 1 de febrero de 1991

Properties of the B oligomer of pertussis toxin

artículo científico publicado en 1991

Protease susceptibility and toxicity of heat-labile enterotoxins with a mutation in the active site or in the protease-sensitive loop

artículo científico publicado en 1997

Protective efficacy induced by recombinant Clostridium difficile toxin fragments

scientific article published on 28 May 2013

Protective immune responses to meningococcal C conjugate vaccine after intranasal immunization of mice with the LTK63 mutant plus chitosan or trimethyl chitosan chloride as novel delivery platform

artículo científico publicado en 2005

Protective levels of diphtheria-neutralizing antibody induced in healthy volunteers by unilateral priming-boosting intranasal immunization associated with restricted ipsilateral mucosal secretory immunoglobulin a

artículo científico publicado en 2003

Protein Export

Pseudoparticle neutralization is a reliable assay to measure immunity and cross-reactivity to H5N1 influenza viruses

article

Public health. Rethinking influenza

artículo científico publicado en 2009

Purification of gonococcal R-type lipopolysaccharide not bearing the lactose-like antigen

scientific article published on 01 July 1981

Pushing the limits of cellular microbiology: microarrays to study bacteria-host cell intimate contacts

artículo científico publicado en 2000

Putative vaccine antigens from Neisseria meningitidis recognized by serum antibodies of young children convalescing after meningococcal disease

artículo científico publicado en 2004

Qualitative and quantitative assessment of meningococcal antigens to evaluate the potential strain coverage of protein-based vaccines

artículo científico publicado en 2010

Rapidly produced SAM(®) vaccine against H7N9 influenza is immunogenic in mice.

artículo científico publicado en 2013

Rational Design of a Glycoconjugate Vaccine against Group A Streptococcus

scientific article published on 13 November 2020

Rational design of a meningococcal antigen inducing broad protective immunity

artículo científico publicado en 2011

Rationally designed strings of promiscuous CD4+ T cell epitopes provide help toHaemophilus influenzae type b oligosaccharide: a model for new conjugate vaccines

artículo científico publicado en 2001

Recognition of Neisseria meningitidis by the long pentraxin PTX3 and its role as an endogenous adjuvant

artículo científico publicado en 2015

Recombinant BCG Expressing LTAK63 Adjuvant induces Superior Protection against Mycobacterium tuberculosis

artículo científico publicado en 2017

Recombinant Mycobacterium bovis BCG Expressing Pertussis Toxin Subunit S1 Induces Protection against an Intracerebral Challenge with Live Bordetella pertussis in Mice.

artículo científico publicado en 2001

Recombinant acellular pertussis vaccine--from the laboratory to the clinic: improving the quality of the immune response

artículo científico publicado el 1 de octubre de 1992

Recombinant bacterial vaccines ⬇️

artículo científico publicado el 26 de abril de 2012

Recombinant microbial ADP-ribosylating toxins of Bordetella pertussis, Vibrio cholerae, and enterotoxigenic Escherichia coli: structure, function, and toxoid vaccine development.

artículo científico publicado en 1994

Rediscovering complement, the first barrier of innate immunity

artículo científico publicado en 2008

Response of the bvg regulon of Bordetella pertussis to different temperatures and short-term temperature shifts

artículo científico publicado en 1995

Reverse Vaccinology and Genomics ⬇️

artículo científico publicado el 24 de octubre de 2003

Reverse Vaccinology: Developing Vaccines in the Era of Genomics ⬇️

artículo científico publicado el 29 de octubre de 2010

Reverse vaccinology

artículo científico publicado en 2000

Reverse vaccinology

artículo científico publicado en 2003

Reverse vaccinology 2.0: Human immunology instructs vaccine antigen design

artículo científico publicado en 2016

Reverse vaccinology and vaccines for serogroup B Neisseria meningitidis

scientific article published on 01 January 2005

Reverse vaccinology in the 21st century: improvements over the original design

artículo científico

Reverse vaccinology, a genome-based approach to vaccine development

artículo científico publicado en 2001

Reverse vaccinology: a genome-based approach for vaccine development

artículo científico publicado en 2002

Role of ARF6, Rab11 and external Hsp90 in the trafficking and recycling of recombinant-soluble Neisseria meningitidis adhesin A (rNadA) in human epithelial cells

artículo científico publicado en 2014

Role of O-Acetylation in the Immunogenicity of Bacterial Polysaccharide Vaccines

artículo científico publicado en 2018

RrgA is a pilus-associated adhesin in Streptococcus pneumoniae

artículo científico publicado en 2007

RrgB321, a fusion protein of the three variants of the pneumococcal pilus backbone RrgB, is protective in vivo and elicits opsonic antibodies

artículo científico publicado en 2011

SARS vaccine protective in mice

artículo científico publicado en 2005

SARS--beginning to understand a new virus

artículo científico publicado en 2003

SARS: understanding the virus and development of rational therapy

artículo científico publicado en 2005

SR-A, MARCO and TLRs differentially recognise selected surface proteins from Neisseria meningitidis: an example of fine specificity in microbial ligand recognition by innate immune receptors

artículo científico publicado en 2008

Safety and immunogenicity of an intramuscular Helicobacter pylori vaccine in noninfected volunteers: a phase I study

artículo científico publicado en 2008

Safety of AS03-adjuvanted influenza vaccines: A review of the evidence

artículo científico publicado en 2019

Save the microbes to save the planet. A call to action of the International Union of the Microbiological Societies (IUMS)

artículo científico publicado en 2023

Seasonal influenza vaccine provides priming for A/H1N1 immunization

artículo científico publicado en 2009

Selective increase of the permeability of polarized epithelial cell monolayers by Helicobacter pylori vacuolating toxin ⬇️

artículo científico publicado el 15 de agosto de 1998

Selective inhibition of Ii-dependent antigen presentation by Helicobacter pylori toxin VacA.

artículo científico publicado en 1998

Self-Assembling Nanoparticles Usher in a New Era of Vaccine Design

artículo científico publicado en 2019

Self-assembling protein nanoparticles in the design of vaccines

artículo científico publicado en 2016

Seminars in Immunology. Technologies and opportunities for vaccines. Introduction

artículo científico publicado en 2013

Sequence constancies and variations in genes encoding three new meningococcal vaccine candidate antigens

scientific article published on 16 November 2005

Sequence type 1 group B Streptococcus, an emerging cause of invasive disease in adults, evolves by small genetic changes

artículo científico publicado en 2015

Sequential activation and environmental regulation of virulence genes in Bordetella pertussis ⬇️

artículo científico publicado el 1 de diciembre de 1991

Shelter from the cytokine storm: pitfalls and prospects in the development of SARS-CoV-2 vaccines for an elderly population

artículo científico publicado en 2020

Short Vi-polysaccharide abrogates T-independent immune response and hyporesponsiveness elicited by long Vi-CRM197 conjugate vaccine

artículo científico publicado en 2020

Short-term and mid-term solutions for influenza vaccines

artículo científico publicado en 2018

Size fractionation of bacterial capsular polysaccharides for their use in conjugate vaccines

artículo científico publicado en 1999

Solution Structure of the Factor H-binding Protein, a Survival Factor and Protective Antigen of Neisseria meningitidis

artículo científico publicado en 2009

Solution structure of the immunodominant domain of protective antigen GNA1870 of Neisseria meningitidis

artículo científico publicado en 2005

Sortase A confers protection against Streptococcus pneumoniae in mice

artículo científico publicado en 2009

Staphylococcus aureus coagulase R domain, a new evasion mechanism and vaccine target

artículo científico publicado en 2016

Strategic Planning in Population Health and Public Health Practice: A Call to Action for Higher Education

artículo científico publicado en 2016

Streptococcus pneumoniae contains 3 rlrA pilus variants that are clonally related

artículo científico publicado en 2008

Streptococcus pneumoniae pilus subunits protect mice against lethal challenge

artículo científico publicado en 2006

Structural and biochemical studies of HCMV gH/gL/gO and Pentamer reveal mutually exclusive cell entry complexes

artículo científico publicado en 2015

Structural and genetic analysis of the bvg locus in Bordetella species ⬇️

artículo científico publicado el 1 de octubre de 1991

Structural basis for immunization with postfusion respiratory syncytial virus fusion F glycoprotein (RSV F) to elicit high neutralizing antibody titers

artículo científico publicado en 2011

Structural basis for lack of toxicity of the diphtheria toxin mutant CRM197 ⬇️

artículo científico publicado el 19 de marzo de 2012

Structural insight into the mechanism of DNA-binding attenuation of the Neisserial adhesin repressor NadR by the small natural ligand 4-hydroxyphenylacetic acid

artículo científico publicado en 2012

Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody

scientific article published on 12 May 2022

Structural vaccinology starts to deliver

artículo científico publicado en 2012

Structure and dynamics of the pan-genome of Streptococcus pneumoniae and closely related species

artículo científico publicado en 2010

Structure and mucosal adjuvanticity of cholera and Escherichia coli heat-labile enterotoxins

artículo científico publicado en 1999

Structure of a protective epitope of group B Streptococcus type III capsular polysaccharide

artículo científico publicado en 2017

Structure of a protective epitope reveals the importance of acetylation of Neisseria meningitidis serogroup A capsular polysaccharide

artículo científico publicado en 2020

Structure of the meningococcal vaccine antigen NadA and epitope mapping of a bactericidal antibody

artículo científico publicado en 2014

Structure of the neutrophil-activating protein from Helicobacter pylori

artículo científico publicado en 2002

Structure-based antigen design: a strategy for next generation vaccines

artículo científico publicado en 2008

Structure-based approach to rationally design a chimeric protein for an effective vaccine against Group B Streptococcus infections

artículo científico publicado en 2011

Studies of the antigenic structure of two cross-reacting proteins, pertussis and cholera toxins, using synthetic peptides

artículo científico publicado en 1989

Subunit S1 of pertussis toxin: mapping of the regions essential for ADP-ribosyltransferase activity

artículo científico publicado en 1988

Successful induction of protective antibody responses against Haemophilus influenzae type b and diphtheria after transcutaneous immunization with the glycoconjugate polyribosyl ribitol phosphate-cross-reacting material 197 vaccine

artículo científico publicado en 2004

Supramolecular Organization of the Repetitive Backbone Unit of the Streptococcus pneumoniae Pilus

artículo científico publicado en 2010

Sustainable vaccine development: a vaccine manufacturer's perspective

scientific article published on 08 May 2018

Synthesis and characterization of a native, oligomeric form of recombinant severe acute respiratory syndrome coronavirus spike glycoprotein

artículo científico publicado en 2004

Synthetic generation of influenza vaccine viruses for rapid response to pandemics

artículo científico publicado en 2013

Systems biology of immunity to MF59-adjuvanted versus nonadjuvanted trivalent seasonal influenza vaccines in early childhood

artículo científico publicado en 2016

Systems vaccinomics: the road ahead for vaccinology

artículo científico publicado en 2011

TIPICO IX: report of the 9th interactive infectious disease workshop on infectious diseases and vaccines

artículo científico publicado en 2019

Targeting infectious diseases in the genomics era.

artículo científico publicado en 2006

Technologies to address antimicrobial resistance

article published in the Proceedings of the National Academy of Sciences of the United States of America

The Escherichia coli heat-labile enterotoxin induces apoptosis of immature lymphocytes in vivo via a glucocorticoid-dependent pathway

artículo científico publicado en 2005

The European effort towards the development of mucosal vaccines for poverty-related diseases

scientific article published on 03 March 2009

The Hsp60 protein of Helicobacter pylori: structure and immune response in patients with gastroduodenal diseases

artículo científico publicado en 1993

The Human Pathogen Streptococcus pyogenes Releases Lipoproteins as Lipoprotein-rich Membrane Vesicles

artículo científico publicado en 2015

The Iron-Responsive Regulator Fur Is Transcriptionally Autoregulated and Not Essential in Neisseria meningitidis ⬇️

artículo científico publicado el 1 de octubre de 2003

The Microbial Pangenome: Implications for Vaccine Development

article

The Novartis Vaccines Institute for Global Health: a new initiative for developing vaccines for neglected diseases in developing countries

artículo científico publicado en 2008

The Pangenome: A Data-Driven Discovery in Biology

artículo científico publicado en 2020

The VacA toxin of Helicobacter pylori identifies a new intermediate filament-interacting protein

artículo científico publicado en 2000

The acquired immune response to the mucosal adjuvant LTK63 imprints the mouse lung with a protective signature

artículo científico publicado en 2007

The adjuvant MF59 induces ATP release from muscle that potentiates response to vaccination

scientific article published on 09 December 2013

The adjuvant effect of a non-toxic mutant of heat-labile enterotoxin of Escherichia coli for the induction of measles virus-specific CTL responses after intranasal co-immunization with a synthetic peptide

artículo científico publicado en 1996

The bvg-dependent promoters show similar behaviour in different Bordetella species and share sequence homologies

artículo científico publicado en 1991

The cag Pathogenicity Island ⬇️

artículo científico publicado el 4 de febrero de 2011

The challenge of developing universal vaccines ⬇️

artículo científico publicado el 1 de enero de 2011

The complete nucleotide sequence of the gene coding for diphtheria toxin in the corynephage omega (tox+) genome ⬇️

artículo científico publicado el 11 de octubre de 1983

The concept of "tailor-made", protein-based, outer membrane vesicle vaccines against meningococcal disease

scientific article published on 01 March 2005

The concomitant use of the LTK63 mucosal adjuvant and of chitosan-based delivery system enhances the immunogenicity and efficacy of intranasally administered vaccines

artículo científico publicado en 2003

The design of semi-synthetic and synthetic glycoconjugate vaccines ⬇️

artículo científico publicado el 6 de septiembre de 2011

The design of vaccines against Helicobacter pylori and their development

artículo científico publicado en 2001

The diphtheria and pertussis components of diphtheria-tetanus toxoids-pertussis vaccine should be genetically inactivated mutant toxins

artículo científico publicado en 2004

The factor H binding protein of Neisseria meningitidis interacts with xenosiderophores in vitro.

artículo científico publicado en 2012

The genome revolution in vaccine research

artículo científico publicado en 2004

The gracefully aging immune system

artículo científico publicado en 2013

The history of MF59®adjuvant: a phoenix that arose from the ashes ⬇️

artículo científico publicado el 1 de enero de 2013

The impact of genomics on vaccine design

artículo científico publicado en 2005

The key role of genomics in modern vaccine and drug design for emerging infectious diseases

artículo científico publicado en 2009

The microbial pan-genome

artículo científico publicado en 2005

The multiple cellular activities of the VacA cytotoxin of Helicobacter pylori

artículo científico publicado en 2004

The neutrophil-activating protein (HP-NAP) of Helicobacter pylori is a potent stimulant of mast cells

artículo científico publicado en 2002

The neutrophil-activating protein of Helicobacter pylori

artículo científico publicado en 2002

The neutrophil-activating protein of Helicobacter pylori (HP-NAP) activates the MAPK pathway in human neutrophils

scientific article published on 01 April 2003

The new multicomponent vaccine against meningococcal serogroup B, 4CMenB: Immunological, functional and structural characterization of the antigens ⬇️

artículo científico publicado el 30 de mayo de 2012

The nucleotide sequence of the gene coding for diphtheria toxoid CRM176.

artículo científico publicado en 1987

The pan-genome: towards a knowledge-based discovery of novel targets for vaccines and antibacterials

artículo científico publicado en 2007

The pertussis toxin liberation genes of Bordetella pertussis are transcriptionally linked to the pertussis toxin operon.

artículo científico publicado en 1996

The quest for a vaccine against Helicobacter pylori: how to move from mouse to man?

artículo científico publicado en 2003

The reaction of bacterial toxins with formaldehyde and its use for antigen stabilization

artículo científico publicado en 1996

The real cost of an affordable vaccine for meningococcus A.

artículo científico publicado en 2003

The region comprising amino acids 100 to 255 of Neisseria meningitidis lipoprotein GNA 1870 elicits bactericidal antibodies

artículo científico publicado en 2005

The response of primary articular chondrocytes to micrometric surface topography and sulphated hyaluronic acid-based matrices

artículo científico publicado en 2005

The role of structural proteomics in vaccine development: recent advances and future prospects

artículo científico

The role of vaccines in combatting antimicrobial resistance

artículo científico publicado en 2021

The safety of vaccines

artículo científico publicado en 2004

The subunit S1 is important for pertussis toxin secretion

scientific article published on 01 October 1990

The use and abuse of a 4-fold increase in antibody response to assess immunogenicity in early stage vaccine clinical trials

scientific article published on 09 December 2019

The use of genomics in microbial vaccine development

artículo científico publicado en 2009

The vaccine containing recombinant pertussis toxin induces early and long-lasting protection

artículo científico publicado en 1999

The vacuolar ATPase proton pump is present on intracellular vacuoles induced by Helicobacter pylori.

artículo científico publicado en 1996

The value of vaccines

artículo científico publicado en 2003

Therapeutic intragastric vaccination against Helicobacter pylori in mice eradicates an otherwise chronic infection and confers protection against reinfection ⬇️

artículo científico publicado el 1 de diciembre de 1997

Therapeutic vaccination against Helicobacter pylori in the beagle dog experimental model: safety, immunogenicity, and efficacy

artículo científico publicado en 2004

Thermoregulation and reversible differentiation in Bordetella: a model for pathogenic bacteria

artículo científico publicado en 1992

Three conserved consensus sequences identify the NAD-binding site of ADP-ribosylating enzymes, expressed by eukaryotes, bacteria and T-even bacteriophages

artículo científico publicado en 1996

Three-Dimensional Reconstruction of Metal Replicas of the Helicobacter pylori Vacuolating Cytotoxin ⬇️

artículo científico publicado el 1 de enero de 1998

Timeline: Vaccines

artículo científico publicado en 2020

Toll-free immunity?

artículo científico publicado en 2008

Toward a meningitis-free world

artículo científico publicado en 2012

Towards a more comprehensive approach for a total economic assessment of vaccines?: 1. The building blocks for a health economic assessment of vaccination.

artículo científico publicado en 2017

Towards a vaccine against Escherichia coli-associated urinary tract infections

artículo científico publicado en 2010

Towards animal free and science based measures of critical quality attributes for vaccine quality control and release

scientific article published on 01 June 2019

Towards deciphering the Helicobacter pylori cytotoxin

artículo científico publicado en 1999

Towards third-generation whooping cough vaccines

artículo científico publicado el 1 de julio de 1991

Toxin inactivation and antigen stabilization: two different uses of formaldehyde

artículo científico publicado en 1994

Transcriptome analysis of Neisseria meningitidis in human whole blood and mutagenesis studies identify virulence factors involved in blood survival

artículo científico publicado en 2011

Transcutaneous immunization with cross-reacting material CRM(197) of diphtheria toxin boosts functional antibody levels in mice primed parenterally with adsorbed diphtheria toxoid vaccine

artículo científico publicado en 2008

Transcutaneous immunization with tetanus toxoid and mutants of Escherichia coli heat-labile enterotoxin as adjuvants elicits strong protective antibody responses.

artículo científico publicado en 2003

Transforming vaccine development

scientific article published on 27 October 2020

Transient facial nerve paralysis (Bell's palsy) following intranasal delivery of a genetically detoxified mutant of Escherichia coli heat labile toxin

artículo científico publicado en 2009

Transmission-Blocking Vaccines for Malaria: Time to Talk about Vaccine Introduction

artículo científico publicado en 2019

Twenty-first century vaccines ⬇️

artículo científico publicado el 12 de octubre de 2011

Two years into reverse vaccinology

artículo científico publicado en 2003

Tyrosine 65 is photolabeled by 8-azidoadenine and 8-azidoadenosine at the NAD binding site of diphtheria toxin

artículo científico publicado en 1991

Tyrosine phosphorylation of the Helicobacter pylori CagA antigen after cag-driven host cell translocation

artículo científico publicado en 2000

Universal vaccines: shifting to one for many

artículo científico publicado en 2010

Unravelling the pathogenic role of Helicobacter pylori in peptic ulcer: potential new therapies and vaccines

artículo científico publicado en 1994

Vaccination against Neisseria meningitidis using three variants of the lipoprotein GNA1870

artículo científico publicado en 2003

Vaccine Evolution and Its Application to Fight Modern Threats

artículo científico publicado en 2019

Vaccine adjuvants: the dream becomes real

artículo científico publicado en 2008

Vaccine adjuvants: the future is bright. Interview by Jenaid Rees

artículo científico publicado en 2013

Vaccine candidates for poor nations are going to waste

artículo científico publicado en 2018

Vaccine composition formulated with a novel TLR7-dependent adjuvant induces high and broad protection against Staphylococcus aureus

artículo científico publicado en 2015

Vaccine discovery and translation of new vaccine technology ⬇️

artículo científico publicado el 12 de junio de 2011

Vaccine informatics

artículo científico publicado en 2010

Vaccine innovations for emerging infectious diseases-a symposium report

scientific article published on 28 October 2019

Vaccine manufacturing: challenges and solutions

artículo científico publicado en 2006

Vaccines Against Antimicrobial Resistance

artículo científico publicado en 2020

Vaccines against Meningococcal Diseases

artículo científico publicado en 2020

Vaccines and antibiotic resistance ⬇️

artículo científico publicado el 12 de septiembre de 2012

Vaccines and global health: In search of a sustainable model for vaccine development and delivery

artículo científico publicado en 2019

Vaccines as remedy for antimicrobial resistance and emerging infections

artículo científico publicado en 2020

Vaccines for Staphylococcus aureus and Target Populations

artículo científico publicado en 2017

Vaccines for the future: learning from human immunology ⬇️

artículo científico publicado el 31 de agosto de 2011

Vaccines for the twenty-first century society ⬇️

artículo científico publicado el 4 de noviembre de 2011

Vaccines in the era of genomics: the pneumococcal challenge

artículo científico publicado en 2007

Vaccines to Overcome Antibiotic Resistance: The Challenge of Burkholderia cenocepacia

artículo científico publicado en 2020

Vaccines with MF59 adjuvant expand the antibody repertoire to target protective sites of pandemic avian H5N1 influenza virus

artículo científico publicado en 2010

Vaccines with the MF59 adjuvant do not stimulate antibody responses against squalene

artículo científico publicado en 2006

Vaccines, Reverse Vaccinology, and Bacterial Pathogenesis ⬇️

artículo científico publicado el 1 de mayo de 2013

Vaccines, emerging viruses, and how to avoid disaster

artículo científico publicado en 2014

Vaccines, new opportunities for a new society

artículo científico publicado en 2014

Vaccines: An achievement of civilization, a human right, our health insurance for the future

article

Vaccines: ideal drugs for the 21st century?

scientific article published on 01 January 2001

Vaccines: science, health, longevity, and wealth

artículo científico publicado en 2014

Vaccinology - Editorial

scientific article published on 07 December 2020

Vaccinology at the beginning of the 21st century

artículo científico publicado en 2005

Vaccinology in the genome era.

artículo científico publicado en 2009

Vacuolation induced by VacA toxin of Helicobacter pylori requires the intracellular accumulation of membrane permeant bases, Cl− and water ⬇️

artículo científico publicado el 23 de noviembre de 2001

Variability of genes encoding surface proteins used as vaccine antigens in meningococcal endemic and epidemic strain panels from Norway

artículo científico publicado en 2014

Vir90, a virulence-activated gene coding for a Bordetella pertussis iron-regulated outer membrane protein

artículo científico publicado en 2003

Vision for a systems architecture to integrate and transform population health

article published in the Proceedings of the National Academy of Sciences of the United States of America

Visualizing bacterial surfaces in real time ⬇️

artículo científico publicado el 1 de marzo de 2009

What are affordable vaccines?

artículo científico publicado en 2015

Will Systems Biology Deliver Its Promise and Contribute to the Development of New or Improved Vaccines? Systems Biology Views of Vaccine Innate and Adaptive Immunity

artículo científico publicado en 2017

c-Src/Lyn kinases activate Helicobacter pylori CagA through tyrosine phosphorylation of the EPIYA motifs

artículo científico publicado en 2002

cag, a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors

artículo científico publicado en 1996

Lista de obras de Rino Rappuoli

2. How is the economic assessment of vaccines performed today?

3. How comprehensive can we be in the economic assessment of vaccines?

3D imaging of the 58 kDa cell binding subunit of the Helicobacter pylori cytotoxin

4CMenB Immunization Induces Serum Bactericidal Antibodies Against Non-Serogroup B Meningococcal Strains in Adolescents

4CMenB vaccine induces elite cross-protective human antibodies that compete with human factor H for binding to meningococcal fHbp

A 2020 vision for vaccines against HIV, tuberculosis and malaria

A C terminus cysteine of diphtheria toxin B chain involved in immunotoxin cell penetration and cytotoxicity

A Crisis of Public Confidence in Vaccines ⬇️

A beta-glucan-conjugate vaccine and anti-beta-glucan antibodies are effective against murine vaginal candidiasis as assessed by a novel in vivo imaging technique

A common conserved amino acid motif module shared by bacterial and intercellular adhesins: bacterial adherence mimicking cell cell recognition?

A genetically detoxified derivative of heat-labile Escherichia coli enterotoxin induces neutralizing antibodies against the A subunit

A mutant pertussis toxin molecule that lacks ADP-ribosyltransferase activity, PT-9K/129G, is an effective mucosal adjuvant for intranasally delivered proteins

A non-living nasal influenza vaccine can induce major humoral and cellular immune responses in humans without the need for adjuvants

A novel epigenetic regulator associated with the hypervirulent Neisseria meningitidis clonal complex 41/44.

A novel glyco-conjugate vaccine against fungal pathogens

A priority-setting aid for new vaccine candidates

A recombinant DNA approach to the pertussis vaccine

A second pilus type in Streptococcus pneumoniae is prevalent in emerging serotypes and mediates adhesion to host cells

A structural overview of the Helicobacter cytotoxin

A sweet T cell response

A universal vaccine for serogroup B meningococcus

ADITEC: joining forces for next-generation vaccines

Acellular pertussis vaccine composed of genetically inactivated pertussis toxin.

Acellular pertussis vaccines: a turning point in infant and adolescent vaccination.

Adjuvant activity of Mycobacterium bovis BCG expressing CRM197 on the immune response induced by BCG expressing tetanus toxin fragment C.

Adjuvant effect of non-toxic mutants of E. coli heat-labile enterotoxin following intranasal, oral and intravaginal immunization

Adjuvant is necessary for a robust immune response to a single dose of H1N1 pandemic flu vaccine in mice.

Adjuvanted H5N1 vaccine induces early CD4+ T cell response that predicts long-term persistence of protective antibody levels

Adjuvanticity of the oil-in-water emulsion MF59 is independent of Nlrp3 inflammasome but requires the adaptor protein MyD88

Adjuvanting a subunit COVID-19 vaccine to induce protective immunity

Aflunov®: a vaccine tailored for pre-pandemic and pandemic approaches against influenza

Ageing and immunity: addressing immune senescence to ensure healthy ageing

Alum adjuvanticity: unraveling a century old mystery

An MF59-adjuvanted inactivated influenza vaccine containing A/Panama/1999 (H3N2) induced broader serological protection against heterovariant influenza virus strain A/Fujian/2002 than a subunit and a split influenza vaccine

An analysis of the sequence variability of meningococcal fHbp, NadA and NHBA over a 50-year period in the Netherlands

An anti-repression Fur operator upstream of the promoter is required for iron-mediated transcriptional autoregulation in Helicobacter pylori

An audience with... Rino Rappuoli

An efficient method to make human monoclonal antibodies from memory B cells: potent neutralization of SARS coronavirus

An unwanted guest: Neisseria meningitidis - carriage, risk for invasive disease and the impact of vaccination with insight on Italy incidence

Analysis of expression of CagA and VacA virulence factors in 43 strains of Helicobacter pylori reveals that clinical isolates can be divided into two major types and that CagA is not necessary for expression of the vacuolating cytotoxin

Anatomy of Omicron BA.1 and BA.2 neutralizing antibodies in COVID-19 mRNA vaccinees

Antibodies to influenza nucleoprotein cross-react with human hypocretin receptor 2.

Antibody to genome-derived neisserial antigen 2132, a Neisseria meningitidis candidate vaccine, confers protection against bacteremia in the absence of complement-mediated bactericidal activity

Antibody-dependent macrophage-mediated activity against Helicobacter pylori in the absence of complement

Anticipating crisis: towards a pandemic flu vaccination strategy through alignment of public health and industrial policy

Antigenic recognition of pertussis and cholera toxin by the same antipeptide antibodies

Antimicrobial resistance and the role of vaccines

Application of microbial genomic science to advanced therapeutics

Are serological responses to acellular pertussis antigens sufficient criteria to ensure that new combination vaccines are effective for prevention of disease?

Auto ADP-ribosylation of NarE, a Neisseria meningitidis ADP-ribosyltransferase, regulates its catalytic activities

Auto-Assembling Detoxified Staphylococcus aureus Alpha-Hemolysin Mimicking the Wild-Type Cytolytic Toxin

Autoregulation of Helicobacter pylori Fur revealed by functional analysis of the iron-binding site

Bacterial pathogen genomics and vaccines.

Beta-glucan-CRM197 conjugates as candidates antifungal vaccines

Beyond cost-effectiveness: Using systems analysis for infectious disease preparedness

Big science for vaccine development

Biochemical and biological characteristics of cross-reacting material 197 (CRM197), a non-toxic mutant of diphtheria toxin: Use as a conjugation protein in vaccines and other potential clinical applications ⬇️

Biotechnology and vaccines: application of functional genomics to Neisseria meningitidis and other bacterial pathogens

Blocking bacterial enterotoxins

Bordetella parapertussis and Bordetella bronchiseptica contain transcriptionally silent pertussis toxin genes

Bridging the gap: need for a data repository to support vaccine prioritization efforts

Bridging the knowledge gaps in vaccine design

Bringing influenza vaccines into the 21st century.

Building an insurance against modern pandemics.

Cell penetration of diphtheria toxin. Reduction of the interchain disulfide bridge is the rate-limiting step of translocation in the cytosol

Cellular microbiology emerging

Cellular pertussis vaccine containing a Bordetella pertussis strain that produces a nontoxic pertussis toxin molecule

Changing Priorities in Vaccinology: Antibiotic Resistance Moving to the Top.

Changing route: aerosol vaccine against tuberculosis

Characterization and immunogenicity of the CagF protein of the cag pathogenicity island of Helicobacter pylori

Characterization of an IS-like element from Mycobacterium tuberculosis

Characterization of diverse subvariants of the meningococcal factor H (fH) binding protein for their ability to bind fH, to mediate serum resistance, and to induce bactericidal antibodies

Characterization of the HspR-mediated stress response in Helicobacter pylori

Characterization of the antibody response to pneumococcal glycoconjugates and the effect of heat-labile enterotoxin on IGg subclasses after intranasal immunization

Chemistry of a new investigational quadrivalent meningococcal conjugate vaccine that is immunogenic at all ages

Chlamydia trachomatis control requires a vaccine ⬇️

Clonal success of piliated penicillin nonsusceptible pneumococci ⬇️

Cloning of a novel pilin-like gene from Bordetella pertussis: homology to the fim2 gene

Combination adjuvants for the induction of potent, long-lasting antibody and T-cell responses to influenza vaccine in mice.