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Lista de obras de Wiebke Arlt

11-Oxygenated C19 Steroids Are the Predominant Androgens in Polycystic Ovary Syndrome

artículo científico publicado en 2016

11-oxygenated estrogens are a novel class of human estrogens but do not contribute to the circulating estrogen pool

artículo científico publicado en 2020

11β-Hydroxysteroid dehydrogenase type 1 inhibition in idiopathic intracranial hypertension: a double-blind randomized controlled trial

artículo científico publicado en 2020

11βHSD1 inhibition with AZD4017 improves lipid profiles and lean muscle mass in Idiopathic intracranial hypertension

artículo científico publicado en 2020

46,XY disorder of sex development in a sudanese patient caused by a novel mutation in the HSD17B3 gene

artículo científico publicado en 2014

A Feminizing Adrenocortical Carcinoma in the Context of a Late Onset 21-Hydroxylase Deficiency

artículo científico publicado en 2014

A Novel Entity of Clinically Isolated Adrenal Insufficiency Caused by a Partially Inactivating Mutation of the Gene Encoding for P450 Side Chain Cleavage Enzyme (CYP11A1)

article

A SULT2A1 genetic variant identified by GWAS as associated with low serum DHEAS does not impact on the actual DHEA/DHEAS ratio

artículo científico publicado en 2013

A detour guide to the Endocrine Society Clinical Practice Guideline on case detection, diagnosis and treatment of patients with primary aldosteronism

artículo científico publicado en 2009

A diagnosis not to be missed: nonclassic steroid 11β-hydroxylase deficiency presenting with premature adrenarche and hirsutism

artículo científico publicado en 2013

A liquid chromatography-tandem mass spectrometry assay for the profiling of classical and 11-oxygenated androgens in saliva

scientific article published on 09 May 2019

A male twin infant with skull deformity and elevated neonatal 17-hydroxyprogesterone: a prismatic case of P450 oxidoreductase deficiency

artículo científico publicado en 2004

A missense mutation in the human cytochrome b5 gene causes 46,XY disorder of sex development due to true isolated 17,20 lyase deficiency

artículo científico publicado en 2012

A new dawn for androgens: Novel lessons from 11-oxygenated C19 steroids.

artículo científico publicado en 2016

A novel high-throughput assay for the measurement of salivary progesterone by liquid chromatography tandem mass spectrometry

artículo científico publicado en 2018

A pharmacokinetic and pharmacodynamic study of delayed- and extended-release hydrocortisone (Chronocort) vs. conventional hydrocortisone (Cortef) in the treatment of congenital adrenal hyperplasia

artículo científico publicado en 2009

A phase 2 study of Chronocort, a modified-release formulation of hydrocortisone, in the treatment of adults with classic congenital adrenal hyperplasia

artículo científico publicado en 2014

A unique androgen excess signature in idiopathic intracranial hypertension is linked to cerebrospinal fluid dynamics

artículo científico publicado en 2019

AKR1C3-Mediated Adipose Androgen Generation Drives Lipotoxicity in Women With Polycystic Ovary Syndrome.

artículo científico publicado en 2017

AKR1D1 is a novel regulator of metabolic phenotype in human hepatocytes and is dysregulated in non-alcoholic fatty liver disease

scientific article published on 19 July 2019

AKR1D1 regulates glucocorticoid availability and glucocorticoid receptor activation in human hepatoma cells

artículo científico publicado en 2019

Accurate non-invasive diagnosis and staging of non-alcoholic fatty liver disease using the urinary steroid metabolome

scientific article published on 16 April 2020

Acute Hypercortisolemia Exerts Depot-Specific Effects on Abdominal and Femoral Adipose Tissue Function

artículo científico publicado en 2017

Adipose tissue-specific androgen generation fuels an adverse metabolic phenotype in patients with polycystic ovary syndrome

Adrenal corticosteroid biosynthesis, metabolism, and action

artículo científico publicado en 2005

Adrenal crisis causing critical illness related reversible myocardial dysfunction

scientific article published on 17 October 2007

Adrenal crisis in treated Addison's disease: a predictable but under-managed event

artículo científico publicado en 2009

Adrenal crisis. Diagnostic and therapeutic management of acute adrenal cortex insufficiency

artículo científico publicado en 2003

Adrenal insufficiency

artículo científico publicado en 2003

Adrenal insufficiency

artículo científico publicado en 2008

Adrenal suppression in patients taking inhaled glucocorticoids is highly prevalent and management can be guided by morning cortisol

artículo científico publicado en 2015

Adrenocortical insufficiency in Rhodesian sleeping sickness is not attributable to suramin

artículo científico publicado en 1995

Adult consequences of congenital adrenal hyperplasia

artículo científico publicado en 2007

Age-specific changes in sex steroid biosynthesis and sex development

artículo científico publicado en 2007

Altered cortisol metabolism in individuals with HNF1A-MODY

scientific article published on 12 May 2020

Alternative pathway androgen biosynthesis and human fetal female virilization

artículo científico publicado en 2019

An oral multiparticulate, modified-release, hydrocortisone replacement therapy that provides physiological cortisol exposure

scientific article published on 20 September 2013

Analysis of plasma 3-methoxytyramine, normetanephrine and metanephrine by ultraperformance liquid chromatography-tandem mass spectrometry: utility for diagnosis of dopamine-producing metastatic phaeochromocytoma

artículo científico publicado en 2013

Androgen Therapy in Women: A Reappraisal: An Endocrine Society Clinical Practice Guideline

artículo científico publicado en 2014

Androgen generation in adipose tissue in women with simple obesity--a site-specific role for 17beta-hydroxysteroid dehydrogenase type 5.

artículo científico publicado en 2004

Androgen replacement in women

artículo científico publicado en 2007

Androgen replacement therapy in women

artículo científico publicado en 2012

Androgen replacement therapy in women

artículo científico publicado en 2005

Androgen therapy in women

artículo científico publicado en 2006

Approach to the patient: the adult with congenital adrenal hyperplasia

artículo científico publicado en 2013

Assessment of the Safety of Glucocorticoid Regimens in Combination With Abiraterone Acetate: A Randomized, Open-Label Phase 2 Study

artículo científico publicado en 2019

Association between hypercortisolaemia and adipose tissue blood flow in vivo

artículo científico publicado en 2015

Beyond adrenal and ovarian androgen generation: Increased peripheral 5 alpha-reductase activity in women with polycystic ovary syndrome

artículo científico publicado en 2003

Bilateral Testicular Tumors Resulting in Recurrent Cushing Disease After Bilateral Adrenalectomy.

artículo científico publicado en 2016

Biochemical diagnosis of Antley-Bixler syndrome by steroid analysis

artículo científico publicado en 2004

CT characteristics of pheochromocytoma - Relevance for the evaluation of adrenal incidentaloma

artículo científico publicado en 2019

Can dehydroepiandrosterone or testosterone replacement effectively treat the symptoms of aging?

artículo científico publicado en 2007

Causes, patterns and severity of androgen excess in 1205 consecutively recruited women

artículo científico publicado en 2018

Causes, patterns and severity of androgen excess in 487 consecutively recruited pre- and post-pubertal children

artículo científico publicado en 2019

Changes over time in sex assignment for disorders of sex development.

artículo científico publicado en 2014

Characterization of the molecular genetic pathology in patients with 11β-hydroxylase deficiency

artículo científico publicado en 2015

Cinnamic acid based thiazolidinediones inhibit human P450c17 and 3beta-hydroxysteroid dehydrogenase and improve insulin sensitivity independent of PPARgamma agonist activity.

artículo científico publicado en 2004

Circulating steroid hormone variations throughout different stages of prostate cancer

artículo científico publicado en 2017

Clinical Spectrum of Primary Adrenal Lymphoma: Results of a Multicenter Cohort Study

scientific article published on 01 June 2020

Clinical and Biochemical Consequences of CYP17A1 Inhibition with Abiraterone Given with and without Exogenous Glucocorticoids in Castrate Men with Advanced Prostate Cancer

scholarly article by Gerhardt Attard et al published February 2012 in The Journal of Clinical Endocrinology and Metabolism

Clinical, Biochemical, and Radiological Characteristics of a Single-Center Retrospective Cohort of 705 Large Adrenal Tumors

artículo científico publicado en 2017

Combination chemotherapy in advanced adrenocortical carcinoma

artículo científico publicado en 2012

Concomitant mutations in the P450 oxidoreductase and androgen receptor genes presenting with 46,XY disordered sex development and androgenization at adrenarche

artículo científico publicado en 2010

Congenital Adrenal Hyperplasia Due to Steroid 21-Hydroxylase Deficiency: An Endocrine Society Clinical Practice Guideline

artículo científico publicado en 2018

Congenital adrenal hyperplasia and P450 oxidoreductase deficiency

artículo científico publicado en 2007

Congenital adrenal hyperplasia caused by mutant P450 oxidoreductase and human androgen synthesis: analytical study

artículo científico publicado en 2004

Congenital adrenal hyperplasia.

artículo científico publicado en 2017

Consensus statement on the diagnosis, treatment and follow-up of patients with primary adrenal insufficiency.

artículo científico

Consider Addison's disease in differential diagnosis of eating disorders in children and young people

artículo científico publicado en 2018

Correction to: Guidelines for the diagnosis and management of critical illness-related corticosteroid insufficiency (CIRCI) in critically ill patients (Part I): Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine

artículo científico publicado en 2018

Cortisol Excess in Patients With Primary Aldosteronism Impacts Left Ventricular Hypertrophy

artículo científico publicado en 2018

Cortisol, DHEA sulphate, their ratio, and all-cause and cause-specific mortality in the Vietnam Experience Study

artículo científico publicado en 2010

Cortisol, DHEAS, their ratio and the metabolic syndrome: evidence from the Vietnam Experience Study

artículo científico publicado en 2010

Cortisol, dehydroepiandrosterone sulphate, their ratio and hypertension: evidence of associations in male veterans from the Vietnam Experience Study

artículo científico publicado en 2011

Cortisone-reductase deficiency associated with heterozygous mutations in 11beta-hydroxysteroid dehydrogenase type 1.

artículo científico publicado en 2011

Critical Illness-Related Corticosteroid Insufficiency (CIRCI): A Narrative Review from a Multispecialty Task Force of the Society of Critical Care Medicine (SCCM) and the European Society of Intensive Care Medicine (ESICM).

artículo científico publicado en 2017

Critical illness-related corticosteroid insufficiency (CIRCI): a narrative review from a Multispecialty Task Force of the Society of Critical Care Medicine (SCCM) and the European Society of Intensive Care Medicine (ESICM).

artículo científico publicado en 2017

Cushing's syndrome due to an ectopic ACTH-secreting pituitary tumour mimicking occult paraneoplastic ectopic ACTH production

scientific article published on 01 December 1999

DAX-1 expression in human adrenocortical neoplasms: implications for steroidogenesis

artículo científico publicado en 1998

DHEA replacement in adrenal insufficiency

artículo científico publicado en 2003

DHEA treatment: myth or reality?

artículo científico publicado en 2002

DHEA: why, when, and how much--DHEA replacement in adrenal insufficiency

artículo científico publicado en 2007

DIAGNOSIS OF ENDOCRINE DISEASE: The diagnostic performance of adrenal biopsy: a systematic review and meta-analysis

artículo científico publicado en 2016

Dehydroepiandrosterone Replacement Therapy

artículo científico publicado en 2004

Dehydroepiandrosterone Supplementation in Healthy Men with an Age-Related Decline of Dehydroepiandrosterone Secretion

Dehydroepiandrosterone and ageing.

artículo científico publicado en 2004

Dehydroepiandrosterone and androstenedione

Dehydroepiandrosterone as a regulator of immune cell function

artículo científico publicado en 2010

Dehydroepiandrosterone exerts antiglucocorticoid action on human preadipocyte proliferation, differentiation, and glucose uptake

artículo científico publicado en 2013

Dehydroepiandrosterone replacement in women with adrenal insufficiency

artículo científico publicado en 1999

Dehydroepiandrosterone replacement in women with adrenal insufficiency: effects on body composition, serum leptin, bone turnover, and exercise capacity

artículo científico publicado en 2001

Dehydroepiandrosterone replacement therapy

Dehydroepiandrosterone replacement therapy

article published in 2001

Dehydroepiandrosterone sulfate directly activates protein kinase C-beta to increase human neutrophil superoxide generation

artículo científico publicado en 2010

Dehydroepiandrosterone supplementation in elderly men: the role of estrogens versus androgens on the male skeleton

artículo científico publicado en 2002

Dehydroepiandrosterone supplementation in healthy men with an age-related decline of dehydroepiandrosterone secretion

artículo científico publicado en 2001

Delayed diagnosis of adrenal insufficiency in a patient with severe penoscrotal hypospadias due to two novel P450 side-change cleavage enzyme (CYP11A1) mutations (p.R360W; p.R405X)

artículo científico publicado en 2012

Deletion of the adrenocorticotropin receptor gene in human adrenocortical tumors: implications for tumorigenesis

scientific article published on 01 September 1997

Diagnosis and Treatment of Primary Adrenal Insufficiency: An Endocrine Society Clinical Practice Guideline

artículo científico publicado en 2016

Diagnosis and management of adrenal insufficiency

artículo científico

Diagnosis of a malignant adrenal mass: the role of urinary steroid metabolite profiling.

artículo científico publicado en 2017

Differential Inhibition of CYP17A1 and CYP21A2 Activities by the P450 Oxidoreductase Mutant A287P

artículo científico publicado en 2007

Dissociation of serum dehydroepiandrosterone and dehydroepiandrosterone sulfate in septic shock

artículo científico publicado en 2006

Double trouble: two cases of dual adrenal pathologies in one adrenal mass

artículo científico publicado en 2019

Editorial

scientific article published on 21 March 2009

Effect of insulin on AKR1C3 expression in female adipose tissue: in-vivo and in-vitro study of adipose androgen generation in polycystic ovary syndrome.

artículo científico publicado en 2015

Endocrinology in the time of COVID-19

scientific article published on 01 April 2020

Endocrinology in the time of COVID-19: Management of adrenal insufficiency

artículo científico publicado en 2020

Enzymatic activities of P450c17 stably expressed in fibroblasts from patients with the polycystic ovary syndrome

artículo científico publicado en 2000

Epidemiology of adrenal tumours in Olmsted County, Minnesota, USA: a population-based cohort study

scientific article published on 01 November 2020

Evidence for Increased 5α-Reductase Activity During Early Childhood in Daughters of Women With Polycystic Ovary Syndrome

artículo científico publicado en 2016

Fine tuning for quality of life: 21st century approach to treatment of Addison's disease

artículo científico publicado en 2009

Fluconazole inhibits human adrenocortical steroidogenesis in vitro

artículo científico publicado en 2012

Functional characterization of threeCYP21A2sequence variants (p.A265V, p.W302S, p.D322G) employing a yeast co-expression system

artículo científico publicado en 2009

Functional consequences of seven novel mutations in the CYP11B1 gene: four mutations associated with nonclassic and three mutations causing classic 11{beta}-hydroxylase deficiency

artículo científico publicado en 2010

Gas chromatography/mass spectrometry (GC/MS) remains a pre-eminent discovery tool in clinical steroid investigations even in the era of fast liquid chromatography tandem mass spectrometry (LC/MS/MS).

artículo científico publicado en 2010

Genetics of congenital adrenal hyperplasia

artículo científico publicado en 2009

Genotype-phenotype analysis in congenital adrenal hyperplasia due to P450 oxidoreductase deficiency

artículo científico publicado en 2011

Genotype-phenotype correlation in 153 adult patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency: analysis of the United Kingdom Congenital adrenal Hyperplasia Adult Study Executive (CaHASE) cohort

artículo científico publicado en 2013

Glucocorticoid activation by 11β-hydroxysteroid dehydrogenase enzymes in relation to inflammation and glycaemic control in chronic kidney disease: a cross-sectional study

scientific article published on 15 November 2018

Glucocorticoid treatment regimen and health outcomes in adults with congenital adrenal hyperplasia

artículo científico publicado en 2013

Glucocorticoids regulate AKR1D1 activity in human liver in vitro and in vivo

artículo científico publicado en 2020

Gorham-Stout disease--stabilization during bisphosphonate treatment

artículo científico publicado en 2004

Guidance for the prevention and emergency management of adult patients with adrenal insufficiency

artículo científico publicado en 2020

Guidelines for the Diagnosis and Management of Critical Illness-Related Corticosteroid Insufficiency (CIRCI) in Critically Ill Patients (Part I): Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM) 2017.

artículo científico publicado en 2017

Guidelines for the diagnosis and management of critical illness-related corticosteroid insufficiency (CIRCI) in critically ill patients (Part I): Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM) 2017.

artículo científico publicado en 2017

Health problems in congenital adrenal hyperplasia due to 21-hydroxylase deficiency

artículo científico publicado en 2011

Health status of adults with congenital adrenal hyperplasia: a cohort study of 203 patients

artículo científico publicado en 2010

Hormones and immune function: implications of aging

artículo científico publicado en 2004

How to avoid precipitating an acute adrenal crisis

artículo científico publicado en 2012

Human DHEA sulfation requires direct interaction between PAPS synthase 2 and DHEA sulfotransferase SULT2A1.

artículo científico publicado en 2018

Human fetal adrenal cells retain age-related stem- and endocrine-differentiation potential in culture

scientific article published on 24 September 2018

Human steroid biosynthesis, metabolism and excretion are differentially reflected by serum and urine steroid metabolomes: A comprehensive review

artículo científico publicado en 2019

Hyperandrogenemia predicts metabolic phenotype in polycystic ovary syndrome: the utility of serum androstenedione

artículo científico publicado en 2014

Hypopituitarism

artículo científico publicado en 2004

Hypothalamic Reproductive Endocrine Pulse Generator Activity Independent of Neurokinin B and Dynorphin Signaling

artículo científico publicado en 2019

Identification of a duplicated P450 side-chain cleavage enzyme (zCyp11a2) defines initiation and maintenance of steroidogenesis in zebrafish

Immediate versus modified release hydrocortisone in mitotane-treated patients with adrenocortical cancer

artículo científico publicado en 2017

Impact of menopause on outcomes in prolactinomas after dopamine agonist treatment withdrawal

scholarly article by Sandhya Santharam et al published 6 July 2018 in Clinical Endocrinology

Impaired 17,20-Lyase Activity in Male Mice Lacking Cytochrome b5 in Leydig Cells

artículo científico publicado en 2016

Impaired hepatic drug and steroid metabolism in congenital adrenal hyperplasia due to P450 oxidoreductase deficiency

artículo científico publicado en 2010

Impaired subjective health status in 256 patients with adrenal insufficiency on standard therapy based on cross-sectional analysis

artículo científico publicado en 2007

Implicating androgen excess in propagating metabolic disease in polycystic ovary syndrome

scientific article published on 24 June 2020

In the arena of adrenal disorders significant progress has been made over the last few years. Preface

artículo científico publicado en 2009

Inactivating PAPSS2 mutations in a patient with premature pubarche

artículo científico publicado en 2009

Incidence, risk factors and clinical significance of postoperative haemodynamic instability after adrenalectomy for phaeochromocytoma

artículo científico publicado en 2019

Increased 5 alpha-reductase activity and adrenocortical drive in women with polycystic ovary syndrome

artículo científico publicado en 2009

Increased Infection Risk in Addison's Disease and Congenital Adrenal Hyperplasia

artículo científico publicado en 2020

Increased central adiposity and decreased subcutaneous adipose tissue 11β-hydroxysteroid dehydrogenase type 1 are associated with deterioration in glucose tolerance-A longitudinal cohort study

artículo científico publicado en 2019

Increased risk of obstructive sleep apnoea in women with polycystic ovary syndrome: a population-based cohort study

Influence of 17-Hydroxyprogesterone, Progesterone and Sex Steroids on Mineralocorticoid Receptor Transactivation in Congenital Adrenal Hyperplasia

artículo científico publicado en 2015

Insights from the genetic characterization of central precocious puberty associated with multiple anomalies

artículo científico publicado en 2020

Interactions of abiraterone, eplerenone, and prednisolone with wild-type and mutant androgen receptor: a rationale for increasing abiraterone exposure or combining with MDV3100.

artículo científico publicado en 2012

Intracrine Testosterone Activation in Human Pancreatic β Cells Stimulates Insulin Secretion

scientific article published on 27 August 2020

Intracrine androgen biosynthesis, metabolism and action revisited

artículo científico publicado en 2017

Junior doctors' working hours and the circadian rhythm of hormones

artículo científico publicado en 2006

Karyotype - Phenotype Associations in Patients with Turner Syndrome

scientific article published on 01 April 2019

Lack of hepatic conversion of dehydroepiandrosterone sulfate (DHEAS) to DHEA.

artículo científico publicado en 2004

Lack of utility of SDHB mutation testing in adrenergic metastatic phaeochromocytoma

scientific article published on 01 February 2015

Learning pharmacokinetic models for in vivo glucocorticoid activation

Linking Antley-Bixler syndrome and congenital adrenal hyperplasia: a novel case of P450 oxidoreductase deficiency

Localization and expression of adrenocorticotropic hormone receptor mRNA in normal and neoplastic human adrenal cortex

artículo científico publicado en 1998

MANAGEMENT OF ENDOCRINE DISEASE: Imaging for the diagnosis of malignancy in incidentally discovered adrenal masses: a systematic review and meta-analysis

artículo científico publicado en 2016

MECHANISMS IN ENDOCRINOLOGY: The sexually dimorphic role of androgens in human metabolic disease.

artículo científico publicado en 2017

MON-203 Local Activation of 11-Oxygenated Androgens by AKR1C3 Is the Predominant Source of Androgens in Human Female Adipose Tissue

MON-447 Impact Of Cortisone And Glucocorticoid Metabolites On Bone Turnover Markers in Male Patients With Hypopituitarism.

artículo científico publicado en 2019

Major depressive disorder, generalised anxiety disorder, and their comorbidity: associations with cortisol in the Vietnam Experience Study

artículo científico publicado en 2010

Maligne Tumoren der Nebennierenrinde

artículo científico publicado en 2002

Management of adrenal incidentalomas: European Society of Endocrinology Clinical Practice Guideline in collaboration with the European Network for the Study of Adrenal Tumors

artículo científico publicado en 2016

Management of hypoparathyroidism during pregnancy--report of twelve cases

artículo científico publicado en 1998

Management of the androgen-deficient woman

artículo científico publicado en 2003

Mapping the Steroid Response to Major Trauma From Injury to Recovery: A Prospective Cohort Study

artículo científico publicado en 2020

Measurement of selected androgens using liquid chromatography–tandem mass spectrometry in reproductive-age women with Type 1 diabetes

artículo científico publicado en 2018

Menopausal Status and Abdominal Obesity Are Significant Determinants of Hepatic Lipid Metabolism in Women

artículo científico publicado en 2015

Mitotane Therapy in Adrenocortical Cancer Induces CYP3A4 and Inhibits 5α-Reductase, Explaining the Need for Personalized Glucocorticoid and Androgen Replacement

scientific article published on 16 November 2012

Mitotane treatment in patients with metastatic testicular Leydig cell tutor associated with severe androgen excess.

artículo científico publicado en 2018

Modified-Release and Conventional Glucocorticoids and Diurnal Androgen Excretion in Congenital Adrenal Hyperplasia.

artículo científico publicado en 2017

Modified-release hydrocortisone to provide circadian cortisol profiles

artículo científico publicado en 2009

Molecular and clinical evidence for an ARMC5 tumor syndrome: concurrent inactivating germline and somatic mutations are associated with both primary macronodular adrenal hyperplasia and meningioma

artículo científico publicado en 2015

Molecular evolution of adrenarche: structural and functional analysis of p450c17 from four primate species

artículo científico publicado en 2002

Monogenic Disorders of Adrenal Steroidogenesis

artículo científico publicado en 2018

Multi-parametric cardiovascular magnetic resonance imaging detects subclinical myocardial involvement in patients diagnosed with phaeochromocytoma

Mutant P450 oxidoreductase causes disordered steroidogenesis with and without Antley-Bixler syndrome

artículo científico publicado en 2004

Mutation of proline 409 to arginine in the meander region of cytochrome p450c17 causes severe 17 alpha-hydroxylase deficiency

artículo científico publicado en 2001

Mutations in the genes encoding 11beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase interact to cause cortisone reductase deficiency

artículo científico publicado en 2003

National Cancer Institute

Natural History of Adrenal Incidentalomas With and Without Mild Autonomous Cortisol Excess: A Systematic Review and Meta-analysis

artículo científico publicado en 2019

Natural history of adrenal steroidogenesis in autoimmune Addison's disease following diagnosis and treatment

scientific article published on 17 April 2020

Neuroendocrine dysfunction in African trypanosomiasis. The role of cytokines.

artículo científico publicado en 1998

Neutrophil function in young and old caregivers.

artículo científico publicado en 2015

Nicotinamide Nucleotide Transhydrogenase as a Novel Treatment Target in Adrenocortical Carcinoma

artículo científico publicado en 2018

No evidence for hepatic conversion of dehydroepiandrosterone (DHEA) sulfate to DHEA: in vivo and in vitro studies

artículo científico publicado en 2005

Nomenclature for alleles of the cytochrome P450 oxidoreductase gene

artículo científico publicado en 2009

Nonclassic lipoid congenital adrenal hyperplasia masquerading as familial glucocorticoid deficiency

artículo científico publicado en 2009

Novel H6PDH mutations in two girls with premature adrenarche: 'apparent' and 'true' CRD can be differentiated by urinary steroid profiling

artículo científico publicado en 2013

Novel associations in disorders of sex development: findings from the I-DSD Registry

artículo científico publicado en 2013

Novel methods in adrenal research: a metabolomics approach

scientific article published on 06 February 2019

OR09-5 Importance of Islet Intracrinology for Glucose-Stimulated Insulin Secretion (GSIS) in the Male.

artículo científico publicado en 2019

OR29-2 Mild Autonomous Cortisol Excess (MACE) in Adrenal Incidentalomas - Metabolic Risk Profile and Urinary Steroid Metabolome Analysis in 1208 Prospectively Recruited Patients

OX40 ligand and CD30 ligand are expressed on adult but not neonatal CD4+CD3- inducer cells: evidence that IL-7 signals regulate CD30 ligand but not OX40 ligand expression

artículo científico publicado en 2005

Oral Dehydroepiandrosterone for Adrenal Androgen Replacement: Pharmacokinetics and Peripheral Conversion to Androgens and Estrogens in Young Healthy Females after Dexamethasone Suppression

Oral dehydroepiandrosterone for adrenal androgen replacement: pharmacokinetics and peripheral conversion to androgens and estrogens in young healthy females after dexamethasone suppression

scientific article published on 01 June 1998

Oral glucose tolerance testing but not intravenous glucose administration uncovers hyper-responsiveness of hypothalamo-pituitary-adrenal axis in patients with adrenal incidentalomas

scientific article published on 01 May 2000

Outcome of Cushing's disease following transsphenoidal surgery in a single center over 20 years

artículo científico publicado en 2012

Outcome of Nonfunctioning Pituitary Adenomas That Regrow After Primary Treatment: A Study From Two Large UK Centers

artículo científico publicado en 2017

P450 oxidoreductase deficiency and Antley-Bixler syndrome

artículo científico publicado en 2007

PAPSS2 deficiency causes androgen excess via impaired DHEA sulfation--in vitro and in vivo studies in a family harboring two novel PAPSS2 mutations

artículo científico publicado en 2015

POR R457H is a global founder mutation causing Antley-Bixler syndrome with autosomal recessive trait

Paraneoplastische Hypertrichosis lanuginosa et terminalis bei einer 27jährigen Patientin mit Parotiskarzinom

scientific article published on 01 December 1999

Pheochromocytoma Is Characterized by Catecholamine-Mediated Myocarditis, Focal and Diffuse Myocardial Fibrosis, and Myocardial Dysfunction.

artículo científico publicado en 2016

Plasma Renin Measurements are Unrelated to Mineralocorticoid Replacement Dose in Patients With Primary Adrenal Insufficiency

artículo científico publicado en 2020

Polycystic ovary syndrome, androgen excess, and the risk of nonalcoholic fatty liver disease in women: A longitudinal study based on a United Kingdom primary care database.

artículo científico publicado en 2018

Premature adrenarche: novel lessons from early onset androgen excess

artículo científico publicado en 2011

Prenatal diagnosis of P450 oxidoreductase deficiency (ORD): a disorder causing low pregnancy estriol, maternal and fetal virilization, and the Antley-Bixler syndrome phenotype

artículo científico publicado en 2004

Prenatal diagnosis of congenital adrenal hyperplasia caused by P450 oxidoreductase deficiency

artículo científico publicado en 2013

Prevention of adrenal crisis: cortisol responses to major stress compared to stress dose hydrocortisone delivery

artículo científico publicado en 2020

Primary adrenal insufficiency is associated with impaired natural killer cell function: a potential link to increased mortality.

artículo científico publicado en 2017

Prolactinomas diagnosed in the postmenopausal period: Clinical phenotype and outcomes

artículo científico publicado en 2017

Pubertal presentation in seven patients with congenital adrenal hyperplasia due to P450 oxidoreductase deficiency

artículo científico publicado en 2010

Pubertal timing in boys and girls born to mothers with gestational diabetes mellitus: a systematic review

artículo científico publicado en 2020

Quality of glucocorticoid replacement in adrenal insufficiency: clinical assessment vs. timed serum cortisol measurements

artículo científico publicado en 2006

Quality of life in Addison's disease--the case for DHEA replacement

artículo científico publicado en 2002

Quality of life in adults with congenital adrenal hyperplasia relates to glucocorticoid treatment, adiposity and insulin resistance: United Kingdom Congenital adrenal Hyperplasia Adult Study Executive (CaHASE).

artículo científico publicado en 2013

Quantitative MRI brain in congenital adrenal hyperplasia: in vivo assessment of the cognitive and structural impact of steroid hormones.

artículo científico publicado en 2017

Recommendations for the diagnosis and management of corticosteroid insufficiency in critically ill adult patients: consensus statements from an international task force by the American College of Critical Care Medicine

artículo científico publicado en 2008

Redefining the initiation and maintenance of zebrafish interrenal steroidogenesis by characterizing the key enzyme cyp11a2.

artículo científico publicado en 2013

Relationship between final height and health outcomes in adults with congenital adrenal hyperplasia: United Kingdom congenital adrenal hyperplasia adult study executive (CaHASE).

artículo científico publicado en 2014

Reply to Flück et al.: Alternative androgen pathway biosynthesis drives fetal female virilization in P450 oxidoreductase deficiency

artículo científico publicado en 2020

Residual Adrenal Function in Autoimmune Addison's Disease-Effect of Dual Therapy With Rituximab and Depot Tetracosactide

artículo científico publicado en 2020

Residual adrenal function in autoimmune Addison's disease: improvement after tetracosactide (ACTH1-24) treatment.

artículo científico publicado en 2013

Response Letter to the Editor from Chee et al.: "Prevention of Adrenal Crisis: Cortisol Response to Major Stress Compared to Stress Dose Hydrocortisone Delivery"

artículo científico publicado en 2020

Response Letter to the Editor from Dorin et al.: "Prevention of Adrenal Crisis: Cortisol Response to Major Stress Compared to Stress Dose Hydrocortisone Delivery"

scientific article published on 08 October 2020

Response Letter to the Editor from Sweeney AT: "CT Characteristics of Pheochromocytoma: Relevance for the Evaluation of Adrenal Incidentaloma"

artículo científico publicado en 2020

Role of ALADIN in human adrenocortical cells for oxidative stress response and steroidogenesis

artículo científico publicado en 2015

SAT-368 Natural History Of Adrenal Incidentalomas With And Without Mild Autonomous Cortisol Excess; A Systematic Review And Meta-analysis

SAT-LB002 Steroid Metabolome Analysis Reveals 11-Ketotestosterone as the Most Abundant Androgen in Castration-Resistant Prostate Cancer Patients on Second-Line Therapies.

artículo científico publicado en 2019

SOCIETY FOR ENDOCRINOLOGY ENDOCRINE EMERGENCY GUIDANCE: Emergency management of acute adrenal insufficiency (adrenal crisis) in adult patients

artículo científico publicado en 2016

SURAMIN FOR TREATMENT OF ADRENOCORTICAL CARCINOMA

artículo científico publicado en 1989

Salivary Cortisone Reflects Cortisol Exposure Under Physiological Conditions and After Hydrocortisone

artículo científico publicado en 2016

Sensing and signaling of oxidative stress in chloroplasts by inactivation of the SAL1 phosphoadenosine phosphatase

artículo científico publicado en 2016

Serum testosterone, sex hormone-binding globulin and sex-specific risk of incident type 2 diabetes in a retrospective primary care cohort

scientific article published on 23 October 2018

Sex steroid metabolism in human peripheral blood mononuclear cells changes with aging

artículo científico publicado en 2005

Should androgen supplementation be used for poor ovarian response in IVF?

artículo científico publicado en 2012

Simulation via instant messaging-Birmingham advance (SIMBA) model helped improve clinicians' confidence to manage cases in diabetes and endocrinology

artículo científico publicado en 2020

Single-cell RNA sequencing reveals T helper cells synthesizing steroids de novo to contribute to immune homeostasis

artículo científico publicado en 2014

Society for Endocrinology UK guidance on the initial evaluation of an infant or an adolescent with a suspected disorder of sex development (Revised 2015).

artículo científico publicado en 2015

Steroid 17alpha-hydroxylase deficiency: functional characterization of four mutations (A174E, V178D, R440C, L465P) in the CYP17A1 gene

artículo científico publicado en 2009

Steroid Metabolome Analysis in Disorders of Adrenal Steroid Biosynthesis and Metabolism

scientific article published on 01 December 2019

Steroid Sulfatase Deficiency and Androgen Activation Before and After Puberty.

artículo científico publicado en 2016

Steroid biomarkers and genetic studies reveal inactivating mutations in hexose-6-phosphate dehydrogenase in patients with cortisone reductase deficiency

artículo científico publicado en 2008

Steroid metabolome analysis reveals prevalent glucocorticoid excess in primary aldosteronism

artículo científico publicado en 2017

Steroid treatment in ARDS: a critical appraisal of the ARDS network trial and the recent literature

artículo científico publicado en 2007

Strategies for managing ACTH dependent mineralocorticoid excess induced by abiraterone

artículo científico

Sunitinib Inhibits Cell Proliferation and Alters Steroidogenesis by Down-Regulation of HSD3B2 in Adrenocortical Carcinoma Cells

artículo científico publicado en 2011

Supine or sitting plasma metanephrine screening? A unifying solution for patients and doctors

artículo científico publicado en 2014

Supine or sitting? Economic considerations regarding patient position during plasma metanephrine analysis for the exclusion of chromaffin tumours

scientific article published on 25 September 2014

Synergistic Effects of Ageing and Stress on Neutrophil Function

scholarly article

TAC3/TACR3 mutations reveal preferential activation of gonadotropin-releasing hormone release by neurokinin B in neonatal life followed by reversal in adulthood

artículo científico publicado en 2010

THERAPY OF ENDOCRINE DISEASE: Improvement of cardiovascular risk factors after adrenalectomy in patients with adrenal tumors and subclinical Cushing's syndrome: a systematic review and meta-analysis

artículo científico publicado en 2016

The A-ring reduction of 11-ketotestosterone is efficiently catalysed by AKR1D1 and SRD5A2 but not SRD5A1

artículo científico publicado en 2020

The Early Effects of Rapid Androgen Deprivation on Human Prostate Cancer

artículo científico publicado en 2015

The Regulation of Steroid Action by Sulfation and Desulfation

artículo científico publicado en 2015

The Steroid Metabolome in the Isolated Ovarian Follicle and Its Response to Androgen Exposure and Antagonism

artículo científico publicado en 2017

The adrenal cortex and sexual differentiation during early human development

artículo científico publicado en 2009

The approach to the adult with newly diagnosed adrenal insufficiency

artículo científico publicado en 2009

The contribution of serum cortisone and glucocorticoid metabolites to detrimental bone health in patients receiving hydrocortisone therapy

artículo científico publicado en 2020

The cortisol stress response induced by surgery: A systematic review and meta-analysis

artículo científico publicado en 2018

The differential impact of PAPS synthase isoforms on DHEAS may be explained by an isoform-specific interaction of SULT2A1 with PAPSS2, but not PAPSS1

The human fetal adrenal cortex and the window of sexual differentiation

artículo científico publicado en 2006

The impact of Connshing's syndrome - mild cortisol excess in primary aldosteronism drives diabetes risk

artículo científico publicado en 2017

The modulation of corticosteroid metabolism by hydrocortisone therapy in patients with hypopituitarism increases tissue glucocorticoid exposure

artículo científico publicado en 2015

The role of androgens in PCOS-related insulin resistance

scholarly article by Michael O'Reilly et al published 1 May 2015 in Endocrine Abstracts

The utility of ultra-high performance supercritical fluid chromatography-tandem mass spectrometry (UHPSFC-MS/MS) for clinically relevant steroid analysis.

artículo científico publicado en 2018

Thiazolidinediones but not metformin directly inhibit the steroidogenic enzymes P450c17 and 3beta -hydroxysteroid dehydrogenase

artículo científico publicado en 2001

Treatment and health outcomes in adults with congenital adrenal hyperplasia

artículo científico publicado en 2013

UK guidance on the initial evaluation of an infant or an adolescent with a suspected disorder of sex development

artículo científico publicado en 2011

Understanding the Role of Androgen Action in Female Adipose Tissue

scientific article published on 09 September 2019

Urine Steroid Metabolomics as a Novel Tool for Detection of Recurrent Adrenocortical Carcinoma

artículo científico publicado en 2020

Urine metabolomic phenotyping for detection of adrenocortical carcinoma: still a long way to go - Authors' reply

scientific article published on 01 November 2020

Urine steroid metabolomics as a biomarker tool for detecting malignancy in adrenal tumors

artículo científico publicado en 2011

Urine steroid metabolomics for the differential diagnosis of adrenal incidentalomas in the EURINE-ACT study: a prospective test validation study

artículo científico publicado en 2020

Using corticosteroids in intensive care

artículo científico publicado en 2006

Well-being, mood and calcium homeostasis in patients with hypoparathyroidism receiving standard treatment with calcium and vitamin D.

artículo científico publicado en 2002

What is the best diagnostic and therapeutic management strategy for an Addison patient during pregnancy?

artículo científico publicado en 2013