Filtros de búsqueda

Lista de obras de Ulrike Holzgrabe

'Pro et contra' ionic liquid drugs - Challenges and opportunities for pharmaceutical translation

artículo científico

1,4-Substituted 4-(1H)-pyridylene-hydrazone-type inhibitors of AChE, BuChE, and amyloid-β aggregation crossing the blood-brain barrier

artículo científico publicado en 2013

11 The need for CE methods in pharmacopoeial monographs

11-Aminostrychnine and N-(Strychnine-11-yl)propionamide: Synthesis, Configuration, and Pharmacological Evaluation at Glycine Receptors

scientific article published on 06 August 2019

1H NMR analytical characterization of mineral oil hydrocarbons (PARAFFINS) for pharmaceutical use

artículo científico publicado en 2019

1H NMR approach as an alternative to the classical p-anisidine value method

article published in 2012

1H NMR profiling as an approach to differentiate conventionally and organically grown tomatoes

artículo científico publicado en 2014

1H and 13C nuclear magnetic resonance studies of the sites of protonation in itraconazole and fluconazole

artículo científico publicado en 1999

1H and 19F NMR relaxation studies of fleroxacin with Micrococcus luteus

artículo científico publicado en 2007

1H and13C NMR studies of substituted isoquinolinium derivatives in different solvents

1H,19F and13C NMR spectral data of fifteen gyrase inhibitors and some metabolites

1H-NMR Spectroscopy as a New Tool in the Assessment of the Oxidative State in Edible Oils

35 Jahre Resistenzen gegen Antibiotika

4-[(2E)-2-(4-Chloro-benzyl-idene)hydrazinyl-idene]-1-methyl-1,4-dihydro-pyridine monohydrate

artículo científico publicado en 2010

5α‐Reduktase‐Inhibitoren – Benigne Prostatahyperplasie und vieles mehr. BPH, Alopezie und Co

artículo científico publicado en 2008

A Fast and Efficient Track to Allosteric Modulators of Muscarinic Receptors: Microwave-Assisted Syntheses

A New Bioactive Compound From the Marine Sponge-Derived sp. SBT348 Inhibits Staphylococcal Growth and Biofilm Formation

artículo científico publicado en 2018

A New Molecular Mechanism To Engineer Protean Agonism at a G Protein-Coupled Receptor

artículo científico publicado en 2017

A Novel Mechanism of Inactivating Antibacterial Nitro Compounds in the Human Pathogen Staphylococcus aureus by Overexpression of a NADH-Dependent Flavin Nitroreductase

artículo científico publicado en 2017

A Photoswitchable Dualsteric Ligand Controlling Receptor Efficacy.

artículo científico publicado en 2017

A Sequence of Aldol Condensations and a Michael Addition Giving a Cyclohexenone Ring System

article

A Stable and Highly Potent Hexamethonium Derivative Which Modulates Muscarinic Receptors Allosterically in Guinea-pig Hearts

artículo científico publicado en 1994

A Structural Biology Approach Enables the Development of Antimicrobials Targeting Bacterial Immunophilins

artículo científico publicado en 2014

A cell-permeable inhibitor to trap Gαq proteins in the empty pocket conformation

artículo científico publicado en 2014

A diversity oriented synthesis of natural product inspired molecular libraries

artículo científico publicado en 2017

A long-time stability study of 50 drug substances representing common drug classes of pharmaceutical use

artículo científico publicado en 2019

A miniaturized peptidyl-prolyl isomerase enzyme assay

artículo científico publicado en 2017

A new in star in antibiotic heaven--daptomycin

artículo científico publicado en 2004

A new micellar electrokinetic capillary chromatography method for separation of the components of the aminoglycoside antibiotics

artículo científico publicado en 2003

A new synthetic route to compounds of the AFDX-type with affinity to muscarinic M2-receptor

article published in 2003

A novel class of allosteric modulators of the muscarinic M2 acetylcholine receptor: terphenyl derivatives

A riddle solved--why valerian-hops extract makes you drowsy

artículo científico publicado en 2004

A silver lining on the horizon: new antimycotics

artículo científico publicado en 2003

A small-molecule inhibitor of Nipah virus envelope protein-mediated membrane fusion

artículo científico publicado en 2009

A stability-study of expired ampoules manufactured more than 40 years ago.

artículo científico publicado en 2017

A systematic review of the stability of finished pharmaceutical products and drug substances beyond their labeled expiry dates

artículo científico publicado en 2019

A way out of a malaria-resistance?

artículo científico publicado en 2009

Absolute quantitative (1)h NMR spectroscopy for compound purity determination.

artículo científico publicado en 2014

Acetylcholinesterase inhibitors with photoswitchable inhibition of β-amyloid aggregation

artículo científico publicado en 2014

Agonists with supraphysiological efficacy at the muscarinic M2 ACh receptor.

artículo científico publicado en 2013

Allosteric Modulators and Selective Agonists of Muscarinic Receptors

artículo científico publicado en 2006

Allosteric Modulators of the Tertiary Alkanebisamino-Type. Variation of the Substitution of the Middle Chain Nitrogens

Allosteric effect on muscarinic M2-receptors of derivatives of the alkane-bis-ammonium compound W84. Comparison with bispyridinium-type allosteric modulators

Allosteric ligands for G protein-coupled receptors: a novel strategy with attractive therapeutic opportunities

artículo científico publicado en 2010

Allosteric modulators of ligand binding to muscarinic acetylcholine receptors

Allosteric site in M2 acetylcholine receptors: evidence for a major conformational change upon binding of an orthosteric agonist instead of an antagonist

artículo científico publicado en 2005

Allosteric small molecules unveil a role of an extracellular E2/transmembrane helix 7 junction for G protein-coupled receptor activation

artículo científico publicado en 2007

Alpha blockers and 5-alpha reductase inhibitors

artículo científico publicado en 2008

Alte Wege zu neuen Antibiotika – Platensimycin

artículo científico publicado en 2006

Alternative Wege zu “Multidrug”-resistenten Bakterien via reaktiver Sauerstoffspezies

Alternatives to amino acid analysis for the purity control of pharmaceutical grade L-alanine

artículo científico publicado en 2010

Amadacyclin - a new tetracycline antibiotic in the pipeline

artículo científico publicado en 2010

Amino acid analysis for pharmacopoeial purposes

artículo científico publicado en 2016

Amino acids: Aspects of impurity profiling by means of CE

scientific article published on 01 July 2007

An LC–MS/MS procedure for the quantification of naproxen in human plasma: Development, validation, comparison with other methods, and application to a pharmacokinetic study

article

An old drug as a carcinostatic. The new career of thalidomide

artículo científico publicado en 2007

Analysis of atropine, its degradation products and related substances of natural origin by means of reversed-phase high-performance liquid chromatography

artículo científico publicado en 2004

Analysis of the glucosinolate pattern ofArabidopsis thalianaseeds by capillary zone electrophoresis coupled to electrospray ionization-mass spectrometry

article

Analysis of the molecular size distribution of polyethylene glycols by CE-UV versus HPLC with evaporative light scattering detection

artículo científico publicado en 2008

Analytical challenges in drug counterfeiting and falsification-The NMR approach

scientific article published on 21 December 2010

Analytical characterisation of crude extracts from an African Ancistrocladus species using high-performance liquid chromatography and capillary electrophoresis coupled to ion trap mass spectrometry

artículo científico publicado en 2004

Anatoxin-a(s) — ein bakterielles Organophosphat

artículo científico publicado en 1994

Anti-Schistosomal Activity of Cinnamic Acid Esters: Eugenyl and Thymyl Cinnamate Induce Cytoplasmic Vacuoles and Death in Schistosomula of Schistosoma mansoni

artículo científico publicado en 2015

Anti-bacterial anacardic acid derivatives

artículo científico publicado en 2020

Anti-trypanosomal activities and structural chemical properties of selected compound classes

artículo científico publicado en 2014

Anticancer effects of NSC‑631570 (Ukrain) in head and neck cancer cells: In vitro analysis of growth, invasion, angiogenesis and gene expression

artículo científico publicado en 2019

Antileishmanial and cytotoxic compounds from Valeriana wallichii and identification of a novel nepetolactone derivative.

artículo científico publicado en 2015

Antileishmanial lead structures from nature: analysis of structure-activity relationships of a compound library derived from caffeic Acid bornyl ester.

artículo científico publicado en 2014

Antitrypanosomal activity of quaternary naphthalimide derivatives

artículo científico publicado en 2007

Artemisinin and successors

artículo científico publicado en 2005

Assessment of inhibitory potency of antibiotics by MRI: apparent T 2 as a marker of cell growth

Assignment of the major and minor components of gentamicin for evaluation of batches

Atypical muscarinic allosteric modulation: cooperativity between modulators and their atypical binding topology in muscarinic M2 and M2/M5 chimeric receptors

artículo científico publicado en 2005

Azathioprine-induced reversible EBV-associated Hodgkin-like lymphoma after immunosuppressive therapy for autoimmune hepatitis

artículo científico publicado en 2018

Aziridine-2,3-dicarboxylate inhibitors targeting the major cysteine protease of Trypanosoma brucei as lead trypanocidal agents

artículo científico publicado en 2006

Ball milling – a new concept for predicting degradation profiles in active pharmaceutical ingredients

artículo científico publicado en 2021

Bemerkung zum DPhG-Statement: Wissenschaftliche Pharmazie und Homöopathie

artículo científico publicado en 2006

Bioinspired Ion Pairs Transforming Papaverine into a Protic Ionic Liquid and Salts

artículo científico publicado en 2020

Bioinspired co-crystals of Imatinib providing enhanced kinetic solubility

artículo científico publicado en 2018

Bis(ammonio)alkane-type agonists of muscarinic acetylcholine receptors: synthesis, in vitro functional characterization, and in vivo evaluation of their analgesic activity

artículo científico publicado en 2014

Bisquaternary Ligands of the Common Allosteric Site of M2Acetylcholine Receptors: Search for the Minimum Essential Distances between the Pharmacophoric Elements

artículo científico publicado en 1999

Bisquaternary dimers of strychnine and brucine. A new class of potent enhancers of antagonist binding to muscarinic M2 receptors

artículo científico publicado en 2003

Bistacrine derivatives as new potent antimalarials

artículo científico publicado en 2016

Bistacrines as potential antitrypanosomal agents.

artículo científico publicado en 2017

Bitopic muscarinic agonists and antagonists and uses thereof: a patent evaluation of US20160136145A1.

artículo científico publicado en 2016

Bone penetration of amoxicillin and clavulanic acid evaluated by population pharmacokinetics and Monte Carlo simulation

artículo científico publicado en 2009

CONTRIBUTION OF LATERAL SUBSTITUENTS IN HEPTANE-BISAMMONIUM DERIVATIVES TO THE ALLOSTERIC STABILIZATION OF ANTAGONIST BINDING TO M2-RECEPTORS

artículo científico publicado en 1998

Capillary electrophoresis method for determination of related substances in glutathione reduced drug substance

Capillary electrophoresis separation of phenethylamine enantiomers using amino acid based ionic liquids

artículo científico publicado en 2017

Capillary electrophoretic resolution of the enantiomers of 2,5-dimethyl-4-hydroxy-3(2H)-furanone, the key flavor compounds in strawberry fruit

Capillary zone electrophoresis as a tool for the quality control of goldenseal extracts

artículo científico publicado en 2005

Capillary zone electrophoresis for the determination of amodiaquine and three of its synthetic impurities in pharmaceutical formulations

artículo científico publicado en 2018

Cer(IV) Oxidationen, 10. Mitt.: Oxidation von ω-Phenylalkyldicarbonyl- und dicarbonyl-analogen Verbindungen

Cer(IV)-Oxidationen von β-Aminoketonen. 3. Mitt.: Ein Syntheseweg zu 4-spirosubstituierten 1,2,3,4-Tetrahydroisochinolinen

Cer(IV)-Oxidationen von β-Aminoketonen. Teil IV: Synthese isomerer Phenanthridinone Cerium(IV)

Cer(IV)oxidationen von β-Aminoketonen, 6. Mitt.: Untersuchungen zum Reaktionsverlauf

Cer(IV)oxidationen von β-Aminoketonen, 8. Mitt.: Synthese von im Piperidinteil verschieden substituierten 1,2,3,4-Tetrahydroisochinolinen

Cer(IV)oxidationen von β–Aminoketonen. 7. Mitt.: Synthese von 4-Benzoylisochinolin und des davon abgeleiteten Lactams

Cer(IV)sulfat-Oxidationen: Intramolekulare Cyclisierung von N-Benzyl-β-aminoketonen zu 4-Benzoyl-1,2,3,4-tetrahydroisochinolinen

Cerium(IV)oxidations, Part IX: Cyclization of Diethyl 4-Phenylbutane-1, 1-dicarboxylate

scholarly article by Ulrike Holzgrabe et al published 1993 in Archiv der Pharmazie - Chemistry in Life Sciences

Cerulenin analogues as inhibitors of efflux pumps in drug-resistant Candida albicans

artículo científico publicado en 2009

Characterization of bacterial growth and the influence of antibiotics by means of UV resonance Raman spectroscopy.

artículo científico publicado en 2006

Characterization of complexes between phenethylamine enantiomers and β-cyclodextrin derivatives by capillary electrophoresis-Determination of binding constants and complex mobilities.

artículo científico publicado en 2017

Characterization of polydisperse macrogols and macrogol-based excipients via HPLC and charged aerosol detection

artículo científico publicado en 2018

Charged aerosol detection in pharmaceutical analysis

artículo científico

Charged aerosol detector response modeling for fatty acids based on experimental settings and molecular features: a machine learning approach

scholarly article by Ruben Pawellek et al published 15 July 2021 in Journal of Cheminformatics

Chiral capillary electrophoresis: facts and fiction on the reproducibility of resolution with randomly substituted cyclodextrins

artículo científico publicado en 2004

Chiral discrimination of phenethylamines with β-cyclodextrin and heptakis(2,3-di-O-acetyl)β-cyclodextrin by capillary electrophoresis and NMR spectroscopy

artículo científico publicado en 1994

Cinnamic Acid Bornyl Ester Derivatives from Valeriana wallichii Exhibit Antileishmanial In Vivo Activity in Leishmania major-Infected BALB/c Mice

artículo científico publicado en 2015

Comparable Bioavailability and Disposition of Pefloxacin in Patients with Cystic Fibrosis and Healthy Volunteers Assessed via Population Pharmacokinetics

scientific article published on 10 July 2019

Comparable population pharmacokinetics and pharmacodynamic breakpoints of cefpirome in cystic fibrosis patients and healthy volunteers

artículo científico publicado en 2011

Comparison of Conventional and Microwave Assisted Reactions Giving Aromatic Oxazolidines

Comparison of Cyclodextrin-Dipeptide Inclusion Complexes in the Absence and Presence of Urea by Means of Capillary Electrophoresis, Nuclear Magnetic Resonance and Molecular Modeling

Comparison of Pantoprazole Concentrations in Simultaneous Cerebrospinal Fluid and Serum Samples

artículo científico publicado en 2016

Comparison of chiral electrophoretic separation methods for phenethylamines and application on impurity analysis

artículo científico publicado en 2010

Comparison of established and novel purity tests for the quality control of heparin by means of a set of 177 heparin samples

scientific article published on 08 September 2010

Comparison of extraction efficiency and selectivity between low-temperature pressurized microwave-assisted extraction and prolonged maceration

scientific article published on 31 August 2020

Comparison of pharmacological activities of three distinct kappa ligands (Salvinorin A, TRK-820 and 3FLB) on kappa opioid receptors in vitro and their antipruritic and antinociceptive activities in vivo

artículo científico publicado en 2004

Comparison of structurally different allosteric modulators of muscarinic receptors by self-organizing neural networks.

artículo científico publicado en 1996

Comparison of the pharmacokinetics and pharmacodynamic profile of carumonam in cystic fibrosis patients and healthy volunteers

artículo científico publicado en 2009

Comparison of the separation of aziridine isomers applying heptakis(2,3-di-O-methyl-6-sulfato)beta-CD and heptakis(2,3-di-O-acetyl-6-sulfato)beta-CD in aqueous and nonaqueous systems

artículo científico publicado en 2005

Competitive inhibition of renal tubular secretion of ciprofloxacin and metabolite by probenecid

artículo científico publicado en 2010

Competitive inhibition of renal tubular secretion of gemifloxacin by probenecid

artículo científico publicado en 2009

Composition of OSCS-contaminated heparin occurring in 2008 in batches on the German market

artículo científico publicado en 2010

Contribution of lateral substituents in symmetrical and non-symmetrical heptane-bisammonio compounds to the allosteric stabilization of N-methylscopolamine binding to muscarinic M2 receptors

artículo científico publicado en 2003

Control of Cardiac Function in vivo with a Light-Regulated Drug

Control of impurities in L-aspartic acid and L-alanine by high-performance liquid chromatography coupled with a corona charged aerosol detector

artículo científico publicado en 2009

Controlling Supramolecular Structures of Drugs by Light

artículo científico publicado en 2020

Convergent, short synthesis of the muscarinic superagonist iperoxo

Cooperative interactions at M2 muscarinic acetylcholine receptors: structure/activity relationships in stepwise shortened bispyridinium- and bis(ammonio)alkane-type allosteric modulators

artículo científico publicado en 2003

Corona Charged Aerosol Detector in studying retention and β-cyclodextrin complex stability using RP-HPLC

artículo científico publicado en 2020

Critical aspects of analysis of Micrococcus luteus, Neisseria cinerea, and Pseudomonas fluorescens by means of capillary electrophoresis

artículo científico publicado en 2004

Crystal structure of (3S*,4R*)-4-fluoro-3-(4-meth-oxy-phen-yl)-1-oxo-2-phenyl-1,2,3,4-tetra-hydro-iso-quinoline-4-carb-oxy-lic acid

artículo científico publicado en 2017

Crystal structure of 5,11-di-hydro-pyrido[2,3-b][1,4]benzodiazepin-6-one

artículo científico publicado en 2015

Current role and future perspectives of multivariate (chemometric) methods in NMR spectroscopic analysis of pharmaceutical products

artículo científico

Cyclodextrin-Mediated Enantioseparation in Microemulsion Electrokinetic Chromatography

scientific article published on 01 January 2013

Cytochrome P450 1A2 phenotyping for student laboratories

Design, Synthesis and Evaluation of Novel 2-(Aminoalkyl)-isoindoline-1,3-dione Derivatives as Dual-Binding Site Acetylcholinesterase Inhibitors

artículo científico publicado en 2012

Design, synthesis, and action of oxotremorine-related hybrid-type allosteric modulators of muscarinic acetylcholine receptors

artículo científico publicado en 2006

Designing Hybrids Targeting the Cholinergic System by Modulating the Muscarinic and Nicotinic Receptors: A Concept to Treat Alzheimer's Disease

scholarly article by Daniela Volpato & Ulrike Holzgrabe published 7 December 2018 in Molecules

Determination of binding constants of cyclodextrin inclusion complexes with amino acids and dipeptides by potentiometric titration

artículo científico publicado en 2004

Determination of clotrimazole in mice plasma by capillary electrophoresis

artículo científico publicado en 2003

Determination of erythromycin and related substances in commercial samples using liquid chromatography/ion trap mass spectrometry

scientific article published on 02 October 2006

Determination of free fatty acids in edible oils by1H NMR spectroscopy

Determination of free fatty acids in pharmaceutical lipids by 1H NMR and comparison with the classical acid value

artículo científico publicado en 2013

Determination of protein binding of gyrase inhibitors by means of continuous ultrafiltration

scientific article published on 01 December 1998

Determination of the extent of protein binding of antibiotics by means of an automated continuous ultrafiltration method

artículo científico publicado en 2006

Development and validation of a generic stability-indicating MEEKC method for five fluoroquinolone antibiotics

artículo científico publicado en 2015

Development and validation of a separation method for the diastereomers and enantiomers of aziridine-type protease inhibitors

article

Development of a new type of allosteric modulator of muscarinic receptors: hybrids of the antagonist AF-DX 384 and the hexamethonio derivative W84.

artículo científico publicado en 2004

Development of a simple, rapid, and robust liquid chromatographic method for the simultaneous determination of sulfalene, sulfadoxine, and pyrimethamine in tablets.

artículo científico publicado en 2016

Development of an enhanced separation of erythromycin and its related substances by liquid chromatography

article

Development of simplified HPLC methods for the detection of counterfeit antimalarials in resource-restraint environments

article

Development, synthesis and structure-activity-relationships of inhibitors of the macrophage infectivity potentiator (Mip) proteins of Legionella pneumophila and Burkholderia pseudomallei

artículo científico publicado en 2016

Die Entwicklung selektiver α2-Rezeptor-Agonisten

artículo científico publicado en 2011

Die Fettsäuresynthese als Angriffspunkt

artículo científico publicado en 2012

Die Natur als Apotheke gegen Tropenkrankheiten: Tirandamycin B gegen lymphatische Filariosen ⬇️

artículo científico publicado el 1 de noviembre de 2011

Differentiation of Organically and Conventionally Grown Tomatoes by Chemometric Analysis of Combined Data from Proton Nuclear Magnetic Resonance and Mid-infrared Spectroscopy and Stable Isotope Analysis

artículo científico publicado en 2015

Diffusion ordered NMR spectroscopy measurements as screening method of potential reactions of API and excipients in drug formulations

artículo científico publicado en 2018

Distinguishing paracetamol formulations: Comparison of potentiometric "Electronic Tongue" with established analytical techniques

artículo científico publicado en 2020

Do we know the mechanism of chiral recognition between cyclodextrins and analytes?

artículo científico publicado en 2002

Do we need new drugs against human African trypanosomiasis?

artículo científico publicado en 2013

Drug Discovery: A Modern Decathlon

scientific article published on 06 March 2013

Dualsteric GPCR targeting: a novel route to binding and signaling pathway selectivity

artículo científico publicado en 2008

Dualsteric muscarinic antagonists--orthosteric binding pose controls allosteric subtype selectivity

artículo científico publicado en 2014

Dynamic ligand binding dictates partial agonism at a G protein-coupled receptor.

artículo científico publicado en 2013

E-Z isomerism of anilinomethylenemalonic acid derivatives

Editorial: Pharmazie in unserer Zeit 1/2004

scholarly article by Ulrike Holzgrabe & Fritz Sörgel published January 2004 in Pharmazie in unserer Zeit

Editorial: Pharmazie in unserer Zeit 2/2005

scholarly article by Ulrike Holzgrabe & Ulrich Jaehde published March 2005 in Pharmazie in unserer Zeit

Editorial: Pharmazie in unserer Zeit 2/2006

scholarly article by Ulrike Holzgrabe & Charlotte Kloft published March 2006 in Pharmazie in unserer Zeit

Editorial: Pharmazie in unserer Zeit 2/2008

scholarly article by Ulrike Holzgrabe & Matthias F. Melzig published March 2008 in Pharmazie in unserer Zeit

Editorial: Pharmazie in unserer Zeit 2/2009

scholarly article by Petra Högger & Ulrike Holzgrabe published March 2009 in Pharmazie in unserer Zeit

Editorial: Pharmazie in unserer Zeit 2/2011

artículo científico publicado en 2011

Editorial: Pharmazie in unserer Zeit 3/2007

scholarly article by Ulrike Holzgrabe & Christa E. Müller published May 2007 in Pharmazie in unserer Zeit

Editorial: Pharmazie in unserer Zeit 5/2004

scholarly article by Ulrike Holzgrabe & Peter Christian Schmidt published September 2004 in Pharmazie in unserer Zeit

Editorial: Pharmazie in unserer Zeit 5/2006

scholarly article by Fritz Sörgel & Ulrike Holzgrabe published September 2006 in Pharmazie in unserer Zeit

Editorial: Pharmazie in unserer Zeit 6/2005

scientific article published on 01 January 2005

Editorial: Pharmazie in unserer Zeit 6/2007

scholarly article by Gerd Bendas et al published November 2007 in Pharmazie in unserer Zeit

Editorial: Pharmazie in unserer Zeit 6/2009

artículo científico publicado en 2009

Editorial: Pharmazie in unserer Zeit 6/2010

artículo científico publicado en 2010

Editorial: Pharmazie in unserer Zeit 6/2011

scientific article published on 01 November 2011

Effect of various cyclodextrin derivatives on the resolution of fencamfamine isomers with capillary electrophoresis and nuclear magnetic resonance

article published in 1998

Effect of β-cyclodextrin acetylation on the resolution of phenethylamines with capillary electrophoresis and nuclear magnetic resonance spectroscopy

Effects of fluoroquinolones on HERG channels and on pancreatic beta-cell ATP-sensitive K+ channels

artículo científico publicado en 2006

Elevation of ligand binding to muscarinic M(2) acetylcholine receptors by bis(ammonio)alkane-type allosteric modulators

artículo científico publicado en 2002

Emergency admission of peramivir in the U.S.A

artículo científico publicado en 2010

Enantioseparation by Capillary Electrophoresis Using Cyclodextrins in an Amino Acid-Based Ionic Liquid Running Buffer

artículo científico publicado en 2019

Enantioseparation of chiral tropa alkaloids by means of cyclodextrin-modified microemulsion electrokinetic chromatography

artículo científico publicado en 2007

Enantioseparation of dihydropyridine derivatives by means of neutral and negatively charged beta-cyclodextrin derivatives using capillary electrophoresis

scientific article published on 01 November 2000

Enantioseparation of dopa and related compounds by cyclodextrin-modified microemulsion electrokinetic chromatography

artículo científico publicado en 2008

Enantioseparation of linear and cyclic chiral bis(phenethyl)amines by means of cyclodextrin-modified capillary electrophoresis

scientific article published on 01 September 2001

Enantioseparation of tropa alkaloids by means of anionic cyclodextrin-modified capillary electrophoresis

artículo científico publicado en 1999

Engineered Context-Sensitive Agonism: Tissue-Selective Drug Signaling through a G Protein-Coupled Receptor

artículo científico publicado en 2016

Erratum to: Comparison of established and novel purity tests for the quality control of heparin by means of a set of 177 heparin samples

scholarly article published in Analytical and Bioanalytical Chemistry

Evaluation by monte carlo simulation of the pharmacokinetics of two doses of meropenem administered intermittently or as a continuous infusion in healthy volunteers.

artículo científico publicado en 2005

Evaluation of amino sugar, low molecular peptide and amino acid impurities of biotechnologically produced amino acids by means of CE.

artículo científico publicado en 2002

Evaluation of enantiomeric purity of magnesium-L-aspartate dihydrate

artículo científico publicado en 2014

Evaluation of the extent of protein binding by means of NMR diffusion and relaxation experiments, and automated continuous ultrafiltration.

artículo científico publicado en 2009

Evaluation of the impurity profile of alcuronium by means of capillary electrophoresis

artículo científico publicado en 2002

Evaluation of the impurity profile of amino acids by means of CE.

artículo científico publicado en 2001

Evaluation of the stability of gentamicin in different antibiotic carriers using a validated MEKC method

artículo científico publicado en 2008

Evidence for a multiple binding mode of bispyridinium-type allosteric modulators of muscarinic receptors

article

FRET Studies of Quinolone-Based Bitopic Ligands and Their Structural Analogues at the Muscarinic M1 Receptor

artículo científico publicado en 2017

FRET zur Bestimmung der minimalen Hemmkonzentration von Antibiotika

artículo científico publicado en 2012

Fatty acid composition analysis in polysorbate 80 with high performance liquid chromatography coupled to charged aerosol detection

article

Fenton's oxidation: a tool for the investigation of potential drug metabolites

artículo científico publicado en 2010

Ficts and facts of epinephrine and norepinephrine stability in injectable solutions

artículo científico

FimH-Inhibitoren - eine neue Möglichkeit chronische Harnwegsinfektionen zu behandeln und zu verhindern

artículo científico publicado en 2012

First population pharmacokinetic analysis showing increased quinolone metabolite formation and clearance in patients with cystic fibrosis compared to healthy volunteers

scholarly article by Yuanyuan Jiao et al published 15 October 2018 in European Journal of Pharmaceutical Sciences

Fluorination of Photoswitchable Muscarinic Agonists Tunes Receptor Pharmacology and Photochromic Properties

artículo científico publicado en 2019

Fluorine walk: The impact of fluorine in quinolone amides on their activity against African sleeping sickness

artículo científico publicado en 2018

Focus on PAINS: false friends in the quest for selective anti-protozoal lead structures from Nature?

Future Information Technology Tools for Fighting Substandard and Falsified Medicines in Low- and Middle-Income Countries

scholarly article by Huma Rasheed et al published 2018 in Frontiers in Pharmacology

Geometrical and Structural Dynamics of Imatinib within Biorelevant Colloids

article

Glufosfamid – ein neues Lost-Derivat: PerfektesDrug-Targeting

artículo científico publicado en 2006

H1-Antihistaminika der ersten Generation. Problemlos in der Empfehlung?

artículo científico publicado en 2007

Helfen Sie uns, unseren wissenschaftlichen Nachwuchs zu fördern!

artículo científico publicado en 2008

High-performance liquid chromatography evaluation of the enantiomeric purity of amino acids by means of automated precolumn derivatization with ortho-phthalaldehyde and chiral thiols.

artículo científico publicado en 2016

How safe was oseltamivir care in the flu pandemic?

artículo científico publicado en 2011

Ibuprofen for Alzheimer's?

artículo científico publicado en 2002

Identification and characterization of diarylimidazoles as hybrid inhibitors of butyrylcholinesterase and amyloid beta fibril formation

artículo científico publicado en 2011

Identification and control of impurities in streptomycin sulfate by high-performance liquid chromatography coupled with mass detection and corona charged-aerosol detection

artículo científico publicado en 2011

Identification and quantitation of the ingredients in a counterfeit Vietnamese herbal medicine against rheumatic diseases

scientific article published on 19 April 2014

Improving anti-trypanosomal activity of alkamides isolated from Achillea fragrantissima

artículo científico publicado en 2017

Impurity profile of amino acids?

artículo científico publicado en 2005

Impurity profiling of N,N'-ethylenebis-l-cysteine diethyl ester (Bicisate).

artículo científico publicado en 2017

Impurity profiling of atropine sulfate by microemulsion electrokinetic chromatography

artículo científico publicado en 2006

Impurity profiling of carbocisteine by HPLC-CAD, qNMR and UV/vis spectroscopy

scientific article published on 25 February 2014

Impurity profiling of ibandronate sodium by HPLC–CAD

artículo científico publicado en 2015

Impurity profiling of l -asparagine monohydrate by ion pair chromatography applying low wavelength UV detection

scientific article published on 30 August 2016

Impurity profiling of l-aspartic acid and glycine using high-performance liquid chromatography coupled with charged aerosol and ultraviolet detection

artículo científico publicado en 2020

Impurity profiling of l-methionine by HPLC on a mixed mode column

scientific article published on 02 February 2016

In search of novel agents for therapy of tropical diseases and human immunodeficiency virus

artículo científico publicado en 2007

Indirect Enantioseparation of Amino Acids by CE Using Automated In-Capillary Derivatization with ortho-Phthalaldehyde and N-Acetyl-l-Cysteine

article published in 2016

Influence of charged aerosol detector instrument settings on the ultra-high-performance liquid chromatography analysis of fatty acids in polysorbate 80

scientific article published on 18 September 2018

Influence of the capillary diameter on the separation efficiency and sensitivity: a systematic approach

artículo científico publicado en 2012

Inhibition of cytochrome P450 3A4 by extracts and kavalactones of Piper methysticum (Kava-Kava).

artículo científico publicado en 2002

Inhibition of flucloxacillin tubular renal secretion by piperacillin

artículo científico publicado en 2008

Inhibition of hypusine biosynthesis in plasmodium: a possible, new strategy in prevention and therapy of malaria

artículo científico publicado en 2006

Inhibition von Virulenzfaktoren: Ein neuer Ansatz zur Entwicklung von Antibiotika

artículo científico publicado en 2006

Inhibitoren der New-Delhi-Metallolactamase

artículo científico publicado en 2012

Inhibitors of macrophage infectivity potentiator-like PPIases affect neisserial and chlamydial pathogenicity

artículo científico publicado en 2016

Interaction of (benzylidene-hydrazono)-1,4-dihydropyridines with beta-amyloid, acetylcholine, and butyrylcholine esterases

artículo científico publicado en 2010

Interlaboratory Comparison Test as an Evaluation of Applicability of an Alternative Edible Oil Analysis by (1)H NMR Spectroscopy

artículo científico publicado en 2017

Interlaboratory study of a NACE method for the determination ofR-timolol content inS-timolol maleate: Assessment of uncertainty

artículo científico publicado en 2006

Investigation of Multi-Component Drugs by NMR Spectroscopy

Investigation of tryptophan-related yellowing in parenteral amino acid solution: Development of a stability-indicating method and assessment of degradation products in pharmaceutical formulations

scientific article published on 27 August 2019

Ionic Liquids in Capillary Electrophoresis

artículo científico publicado en 2016

Ionic liquid versus prodrug strategy to address formulation challenges

artículo científico publicado en 2014

Isolation and Characterization of Galloylglucoses Effective against Multidrug-Resistant Strains of Escherichia coli and Klebsiella pneumoniae

artículo científico publicado en 2022

Isolation of a novel compound (MIMO2) from the methanolic extract of Moringa oleifera leaves: protective effects against vanadium-induced cytotoxity

artículo científico publicado en 2017

Kappa-receptor selective binding of opioid ligands with a heterocyclic bicyclo[3.3.1]nonan-9-one structure

artículo científico publicado en 2003

Keto-Enol-Tautomerism and Configurational Isomerism of 2,6-Disubstituted 4-Piperidone-3,5-dicarboxylates

Ketolide und Oxazolidinone in der Pipeline: Und die Reise geht weiter…

artículo científico publicado en 2004

Kleine Änderung, große Wirkung – ein neues Vancomycin-Derivat gegen MRSA

artículo científico publicado en 2006

Lactivicin – ein Antibiotikum gegen Penicillin-resistente Pneumokokken

artículo científico publicado en 2007

Large-scale attack against Plasmodium

artículo científico publicado en 2010

Laser-induced fluorescence-capillary electrophoresis and fluorescence microplate reader measurement: two methods to quantify the effect of antibiotics

artículo científico publicado en 2007

Ligand Binding Ensembles Determine Graded Agonist Efficacies at a G Protein-coupled Receptor

artículo científico publicado en 2016

Ligand-Specific Allosteric Coupling Controls G-Protein-Coupled Receptor Signaling

artículo científico publicado en 2020

Ligand-Specific Restriction of Extracellular Conformational Dynamics Constrains Signaling of the M2 Muscarinic Receptor.

artículo científico publicado en 2017

Ligands for the common allosteric site of acetylcholine M2-receptors: development and application

Lipophilicity and membrane interactions of cationic-amphiphilic compounds: syntheses and structure-property relationships

artículo científico publicado en 2001

Lys05 - ein neuer Ansatz zur Tumortherapie?

M1 muscarinic cetylcholine receptor allosteric modulators as potential therapeutic opportunities for treating Alzheimer's disease

scholarly article by Michael Decker & Ulrike Holzgrabe published 2012 in MedChemComm

MRSA--development, distribution and prevention

artículo científico publicado en 2012

Mapping the pharmaceutical design space by amorphous ionic liquid strategies

artículo científico publicado en 2017

Matrix-assisted laser desorption/ionization tandem mass spectrometry of N-glycans derivatized with isonicotinic hydrazide and its biotinylated form

artículo científico publicado en 2014

Mechanism of action of the diazabicyclononanone-type kappa-agonists

artículo científico publicado en 2003

Mechanochemical Oxidative Degradation of Thienopyridine Containing Drugs: Toward a Simple Tool for the Prediction of Drug Stability

artículo científico publicado en 2023

Meropenem-clavulanate: a new strategy for the treatment of tuberculosis?

artículo científico publicado en 2009

Micellar Electrokinetic Chromatography of Aminoglycosides

Micellar electrokinetic capillary chromatography, high performance liquid chromatography and nuclear magnetic resonance--three orthogonal methods for characterization of critical drugs

artículo científico publicado en 2004

Micellar electrokinetic chromatography of aminoglycosides

artículo científico publicado en 2008

Microwave-enhanced hydrogenations at medium pressure using a newly constructed reactor

article published in 2005

Mode-of-action studies of the novel bisquaternary bisnaphthalimide MT02 against Staphylococcus aureus

artículo científico publicado en 2010

Modeling antibiotic and cytotoxic effects of the dimeric isoquinoline IQ-143 on metabolism and its regulation in Staphylococcus aureus, Staphylococcus epidermidis and human cells

artículo científico publicado en 2011

Molecular alliance-from orthosteric and allosteric ligands to dualsteric/bitopic agonists at G protein coupled receptors

artículo científico publicado en 2012

Multivariate analysis of nuclear magnetic resonance data--characterization of critical drug substance quality of gentamicin sulfate

artículo científico publicado en 2005

Muscarinic Allosteric Modulators: Atypical Structure-Activity-Relationships in Bispyridinium-type Compounds

artículo científico publicado en 2006

Muscarinic allosteric enhancers of ligand binding: pivotal pharmacophoric elements in hexamethonio-type agents

artículo científico publicado en 2005

Muscarinic receptor agonists and antagonists

N+/Si Replacement as a Tool for Probing the Pharmacophore of Allosteric Modulators of Muscarinic M2Receptors: Synthesis, Allosteric Potency, and Positive Cooperativity of Silicon-Based W84 Derivatives

N-(3-Cyanophenyl)-2-phenylacetamide, an effective inhibitor of morbillivirus-induced membrane fusion with low cytotoxicity

artículo científico publicado en 2010

NMR Spectroscopic and Molecular Modelling Studies on Cyclodextrin-Dipeptide Inclusion Complexes

NMR spectroscopy in pharmaceutical and biomedical analysis

artículo científico publicado en 2014

NMR spectroscopy in pharmacy

artículo científico publicado en 1998

NMR techniques in biomedical and pharmaceutical analysis

artículo científico publicado en 2010

Natur häufig Vorbild

Natural Products Repertoire of the Red Sea

artículo científico publicado en 2020

Neue Antibiotika in Sicht?

artículo científico publicado en 2009

Neue Antiepileptika im Überblick

artículo científico publicado en 1997

Neue Hoffnung für Krebspatienten?

artículo científico publicado en 2006

Neue Wege zu selektiven Antiinfektiva

artículo científico publicado en 2005

Neuroprotective Effects of Isosteviol Sodium in Murine Brain Capillary Cerebellar Endothelial Cells (cerebEND) After Hypoxia

artículo científico publicado en 2020

New Griselimycins for Treatment of Tuberculosis

scientific article published on 01 August 2015

New hope for malaria vaccine

artículo científico publicado en 2009

New insight into active muscarinic receptors with the novel radioagonist [³H]iperoxo

artículo científico publicado en 2014

New semiphysiological absorption model to assess the pharmacodynamic profile of cefuroxime axetil using nonparametric and parametric population pharmacokinetics

scientific article published on 15 June 2009

New treatments against AIDS: fusion inhibitors

artículo científico publicado en 2004

Nonlinear pharmacokinetics of piperacillin in healthy volunteers--implications for optimal dosage regimens

artículo científico publicado en 2010

Novel Population Pharmacokinetic Approach to Explain the Differences between Cystic Fibrosis Patients and Healthy Volunteers via Protein Binding

scientific article published on 18 June 2019

Novel bipharmacophoric inhibitors of the cholinesterases with affinity to the muscarinic receptors M1 and M2

artículo científico publicado en 2017

Novel lead compounds in pre-clinical development against African sleeping sickness

article

O-glycoside sequence of pentacyclic triterpene saponins from Phytolacca bogotensis using HPLC-ESI/multi-stage tandem mass spectrometry.

artículo científico publicado en 2009

One-Pot Ugi/Aza-Michael Synthesis of Highly Substituted 2,5-Diketopiperazines with Anti-Proliferative Properties

artículo científico publicado en 2012

Online Monitoring of Microwave-Enhanced Reactions by UV/Vis Spectroscopy

Opening NADPH oxidase inhibitors for in vivo translation

artículo científico publicado en 2017

Optical Control of Cardiac Function with a Photoswitchable Muscarinic Agonist

artículo científico publicado en 2019

Overton's rule helps to estimate the penetration of anti-infectives into patients' cerebrospinal fluid

artículo científico publicado en 2011

Oxidative dehydrogenation of C-C and C-N bonds: A convenient approach to access diverse (dihydro)heteroaromatic compounds

artículo científico publicado en 2017

PAH and many other indications. Old and new endothelin receptor antagonists

artículo científico publicado en 2010

Penetration of antibacterials into bone: pharmacokinetic, pharmacodynamic and bioanalytical considerations

artículo científico publicado en 2009

Penetration of moxifloxacin into bone evaluated by Monte Carlo simulation

artículo científico publicado en 2009

Pentacyclic triterpenes from Cecropia telenitida with immunomodulatory activity on dendritic cells

Pharmacokinetics and pharmacodynamics of antibiotics in intensive care

artículo científico publicado en 2016

Pharmacological, Mechanistic, and Pharmacokinetic Assessment of Novel Melatonin-Tamoxifen Drug Conjugates as Breast Cancer Drugs

scientific article published on 20 June 2019

Phosphorsäureester: Vergiftung und Therapie aus molekularer Sicht

artículo científico publicado en 1990

Photocatalyzed [2 + 2 + 2]-cycloaddition of nitriles with acetylene: an effective method for the synthesis of 2-pyridines under mild conditions

artículo científico publicado en 2002

Pipecolic acid derivatives as small-molecule inhibitors of the Legionella MIP protein

artículo científico publicado en 2010

Piperidones with activity against Plasmodium falciparum

artículo científico publicado en 2006

Plasma Protein Binding of Gyrase Inhibitors

artículo científico publicado en 1998

Plectasin - ein neues Peptidantibiotikum mit hohem therapeutischem Potential

scientific article published on 01 September 2010

Population pharmacokinetic comparison and pharmacodynamic breakpoints of ceftazidime in cystic fibrosis patients and healthy volunteers

artículo científico publicado en 2010

Population pharmacokinetics at two dose levels and pharmacodynamic profiling of flucloxacillin

artículo científico publicado en 2007

Population pharmacokinetics of piperacillin at two dose levels: influence of nonlinear pharmacokinetics on the pharmacodynamic profile

artículo científico publicado en 2012

Predicting critical micelle concentration and micelle molecular weight of polysorbate 80 using compendial methods

artículo científico publicado en 2014

Preface

Probing the size of a hydrophobic binding pocket within the allosteric site of muscarinic acetylcholine M2-receptors

artículo científico publicado en 2000

Problem of counterfeit medicines in Africa and Southeast Asia. Fake anti-malaria drugs and more

artículo científico publicado en 2009

Profiling a gut microbiota-generated catechin metabolite's fate in human blood cells using a metabolomic approach

artículo científico publicado en 2015

Protease inhibitors against hepatitis C

artículo científico publicado en 2004

Protein release from electrospun nonwovens: Improving the release characteristics through rational combination of polyester blend matrices with polidocanol

artículo científico publicado en 2014

Qualitative and quantitative 1 H NMR spectroscopy for determination of divalent metal cation concentration in model salt solutions, food supplements, and pharmaceutical products by using EDTA as chelating agent

scientific article published on 15 February 2020

Quality assessment of unfractionated heparin using 1H nuclear magnetic resonance spectroscopy.

artículo científico publicado en 2008

Quality of the antimalarial medicine artemether - lumefantrine in 8 cities of the Democratic Republic of the Congo

scholarly article by Jean-Pierre Mufusama et al published October 2018 in Drug Testing and Analysis

Quantification of Bisoprolol and Metoprolol in Simultaneous Human Serum and Cerebrospinal Fluid Samples

artículo científico publicado en 2017

Quantification of Hydrochlorothiazide and Ramipril/Ramiprilate in Blood Serum and Cerebrospinal Fluid: A Pharmacokinetic Assessment of Central Nervous System Adverse Effects

artículo científico publicado en 2018

Quantification of taurine in energy drinks using 1H NMR

artículo científico publicado en 2013

Quantitation of talinolol and other beta-blockers by capillary electrophoresis for in vitro drug absorption studies

artículo científico publicado en 2003

Quantitative NMR spectroscopy in pharmaceutical applications

artículo científico publicado en 2010

Quantitative NMR spectroscopy of biologically active substances and excipients

article published in 2010

Quantitative NMR spectroscopy—principles and applications

Quantitative NMR, Methods and Applications

Quantitative liquid chromatography-mass spectrometry determination of isatin in urine using automated on-line extraction

artículo científico publicado en 2002

Quantitative structure-property relationship modeling of polar analytes lacking UV chromophores to charged aerosol detector response

artículo científico publicado en 2019

Quantitative ¹H NMR analysis of egg yolk, alcohol, and total sugar content in egg liqueurs

artículo científico publicado en 2015

Quantitative1H NMR spectroscopic determination of theE/Z isomer ratio of the antidepressant drug fluvoxamine for use in pharmaceutical analysis

Quaternary ammonium salts and their antimicrobial potential: targets or nonspecific interactions?

artículo científico publicado en 2011

Quinolone Amides as Antitrypanosomal Lead Compounds with In Vivo Activity

artículo científico publicado en 2016

Quo Vadis qNMR?

artículo científico publicado en 2019

RAL GTPases mediate multiple myeloma cell survival and are activated independently of oncogenic RAS

scientific article published on 10 October 2019

Random chemistry as a new tool for the generation of small compound libraries: development of a new acetylcholinesterase inhibitor

artículo científico publicado en 2005

Random chemistry as a new tool for the generation of small-compound libraries

artículo científico publicado en 2006

Rational design of dualsteric GPCR ligands: quests and promise

artículo científico publicado en 2010

Rational design of partial agonists for the muscarinic m1 acetylcholine receptor

artículo científico publicado en 2014

Real time observation of microwave-enhanced reactions via fast FTIR spectroscopy

Recent applications of the Charged Aerosol Detector for liquid chromatography in drug quality control

artículo científico publicado en 2020

Reduktionen 3,11-dipyridylsubstituierter 5-Oxo-2,6-methano-2-benzazocin-6-carbonsäureester

Reduktionen an 3,7-Diazabicyclo[3.3.1]nonan-9-onen und 1,3-Diazaadamantan-6-onen1)

Regulatory framework in Pakistan: situation analysis of medicine quality and future recommendations

scientific article published on 11 September 2019

Reply to "Requirements for accurate 1H NMR quantification of mineral oil hydrocarbons (paraffins) for pharmaceutical or cosmetic use"

scientific article published on 10 April 2019

Resolution of ephedrine derivatives by means of neutral and sulfated heptakis(2,3-di-O-acetyl)beta-cyclodextrins using capillary electrophoresis and nuclear magnetic resonance spectroscopy

scientific article published on 01 September 1999

Resolution of newly synthesized racemic dihydropyridines with different chiral selectors by means of capillary electrophoresis

scientific article published on 01 August 1999

Risk assessment report of potential impurities in cetirizine dihydrochloride

artículo científico publicado en 2020

Routine quality control of medicines in developing countries: Analytical challenges, regulatory infrastructures and the prevalence of counterfeit medicines in Tanzania

scholarly article by Ludwig Höllein et al published February 2016 in Trends in Analytical Chemistry

Rückkehr in das Vor‐Semmelweis‐Zeitalter – MRSA, NDM‐1 und was kommt noch? ⬇️

artículo científico publicado el 1 de noviembre de 2010

SARS bereits besiegt?

artículo científico publicado en 2003

Search for dual function inhibitors for Alzheimer's disease: synthesis and biological activity of acetylcholinesterase inhibitors of pyridinium-type and their Abeta fibril formation inhibition capacity

artículo científico publicado en 2005

Search for the Pharmacophore in Kappa-agonistic Diazabicyclo[3.3.1]nonan-9-one-1,5-diesters and Arylacetamides

artículo científico publicado en 1996

Search for the Pharmacophore of Bispyridinium-Type Allosteric Modulators of Muscarinic Receptors

scientific article published on 01 May 1994

Selective estrogen receptor modulators

artículo científico publicado en 2004

Semisynthetic analogues of toxiferine I and their pharmacological properties at α7 nAChRs, muscle-type nAChRs, and the allosteric binding site of muscarinic M2 receptors

artículo científico publicado en 2014

Serjanic Acid Improves Immunometabolic Markers in a Diet-Induced Obesity Mouse Model

artículo científico publicado en 2020

Severe Drug-Induced Liver Injury as an Adverse Drug Event of Antibiotics: A Case Report and Review of the Literature

artículo científico publicado en 2017

Simple and rapid high performance liquid chromatography method for the determination of polidocanol as bulk product and in pharmaceutical polymer matrices using charged aerosol detection

artículo científico publicado en 2014

Stability and assessment of amino acids in parenteral nutrition solutions.

artículo científico publicado en 2017

Stabilization of delphinidin in a complex with sulfobutylether-β-cyclodextrin allows for antinociception in inflammatory pain

scientific article published on 25 September 2020

Stereochemistry of 2,6-Dipyridine Substituted N-Benzyl-4-piperidone Mono- and Dicarboxylates and of the Corresponding Reduction Products

Stereocontrolled synthesis of the enantiomers of 1-[2-hydroxy-3-(4-phenyl-1-piperazinyl)-propyl]-pyrrolidin-2-one

article published in 2001

Stereoselektive Synthese tertiärer 2,6-Methano-2-benzazocin-5-ole

Structurally novel group of ligands selective for kappa opioid receptors

Structure-Effect Relationships of Novel Semi-Synthetic Cannabinoid Derivatives

scientific article published on 20 November 2019

Structure-activity relationship and studies on the molecular mechanism of leishmanicidal N,C-coupled arylisoquinolinium salts

artículo científico publicado en 2009

Structure-activity relationships of strychnine analogs at glycine receptors

artículo científico publicado en 2014

Structure−Activity Relationships in a Series of Bisquaternary Bisphthalimidine Derivatives Modulating the Muscarinic M2-Receptor Allosterically

artículo científico publicado en 2000

Studies on the chiral recognition of peptide enantiomers by neutral and sulfated beta-cyclodextrin and heptakis-(2,3-di-O-acetyl)-beta-cyclodextrin using capillary electrophoresis and nuclear magnetic resonance

artículo científico publicado en 2002

Studies on the stereochemistry of 1,2,6-trimethyl-4-piperidone

Study on the chiral recognition of the enantiomers of ephedrine derivatives with neutral and sulfated heptakis(2,3-O-diacetyl)-beta-cyclodextrins using capillary electrophoresis, UV, nuclear magnetic resonance spectroscopy and mass spectrometry

artículo científico publicado en 2001

Synthese und Stereochemie potentiell stark analgetischer 2,4-m-diarylsubstituierter 3,7-Diazabicyclo[3.3.1]nonan-9-on-1,5-diester

artículo científico publicado en 1992

Syntheses and Biological Activities of NewN1-Aryl Substituted Quinolone Antibacterials

artículo científico publicado en 1996

Synthesis and Nucleophilic Reactions of Cyano SubstitutedN-Methoxyisoquinolinium Salts

Synthesis and X-Ray Analysis of the (S) Enantiomer of Methyl 5-Hydroxy-3,11-di-2-pyridyl-4,5-dihydro-1H,3H-2,6-methano- 6-benz[c]azocinecarboxylate C24H23N3O3 and of the Corresponding Camphanic Acid Ester C34H35N3O6

Synthesis and biological activity of pyridinium-type acetylcholinesterase inhibitors

artículo científico publicado en 2003

Synthesis and evaluation of antitrypanosomal activity of some thiosemicarbazide derivatives of 1-butyl-6-fluoro-7-morpholino-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

Synthesis and opioid receptor affinity of a series of 2, 4-diaryl-substituted 3,7-diazabicylononanones

artículo científico publicado en 2000

Synthesis and structure-activity relationships of new quinolone-type molecules against Trypanosoma brucei

artículo científico publicado en 2012

Synthesis, bioactivity and molecular modeling studies on potential anti-Alzheimer piperidinehydrazide-hydrazones

artículo científico publicado en 2018

Synthesis, biological activity, and docking studies of new acetylcholinesterase inhibitors of the bispyridinium type

artículo científico publicado en 2003

Systematic comparison of the population pharmacokinetics and pharmacodynamics of piperacillin in cystic fibrosis patients and healthy volunteers

artículo científico publicado en 2007

Systematic development of high affinity bis(ammonio)alkane-type allosteric enhancers of muscarinic ligand binding

artículo científico publicado en 2003

Tacrine-xanomeline and tacrine-iperoxo hybrid ligands: Synthesis and biological evaluation at acetylcholinesterase and M1 muscarinic acetylcholine receptors

artículo científico publicado en 2020

Tamper-proof tablets for distinction between counterfeit and originator drugs through PEG coding

artículo científico publicado en 2015

Targeting acetylcholinesterase to treat neurodegeneration

artículo científico publicado en 2007

Targeting protein folding; a novel approach for the treatment of pathogenic bacteria

artículo científico publicado en 2020

Tautomerism of 4-hydroxy-2,5-dimethyl-3(2H)-furanone: evidence for its enantioselective biosynthesis

artículo científico publicado en 2003

The Influence of Fluoroquinolone Drugs on the Bacterial Growth ofS. epidermidisUtilizing the Unique Potential of Vibrational Spectroscopy

article

The Role of Orthosteric Building Blocks of Bitopic Ligands for Muscarinic M1 Receptors

artículo científico publicado en 2020

The allosteric vestibule of a seven transmembrane helical receptor controls G-protein coupling

artículo científico publicado en 2012

The ameliorative effects of a phenolic derivative of Moringa oleifera leave against vanadium-induced neurotoxicity in mice

scientific article published on 12 July 2020

The bisnaphthalimides as new active lead compounds against Plasmodium falciparum

artículo científico publicado en 2010

The contamination of valsartan and other sartans, Part 2: Untargeted screening reveals contamination with amides additionally to known nitrosamine impurities

artículo científico publicado en 2019

The contamination of valsartan and other sartans, part 1: New findings

artículo científico publicado en 2019

The influence of Osmunda regalis root extract on head and neck cancer cell proliferation, invasion and gene expression

artículo científico publicado en 2017

The insulinotropic effect of fluoroquinolones

artículo científico publicado en 2008

The role of solvents in the signal separation for quantitative (1)H NMR spectroscopy

artículo científico publicado en 2009

The use of cyclodextrin-modified capillary electrophoresis in the determination of the enantiomeric purity

artículo científico publicado en 2002

Transformation of acidic poorly water soluble drugs into ionic liquids

artículo científico publicado en 2015

Trypanosomen im Fokus

artículo científico publicado en 2010

Ugi Reaction-Derived α-Acyl Aminocarboxamides Bind to Phosphatidylinositol 3-Kinase-Related Kinases, Inhibit HSF1-Dependent Heat Shock Response, and Induce Apoptosis in Multiple Myeloma Cells.

artículo científico publicado en 2017

Use of collision induced dissociation mass spectrometry as a rapid technique for the identification of pharmacologically active peptides in pharmacopoeial testing

scientific article published on 29 March 2011

Use of evaporative light scattering detection for the quality control of drug substances: Influence of different liquid chromatographic and evaporative light scattering detector parameters on the appearance of spike peaks

artículo científico publicado en 2010

Valeriana wallichii root extracts and fractions with activity against Leishmania spp

artículo científico publicado en 2010

Vibrational spectroscopic characterization of fluoroquinolones

artículo científico publicado en 2005

Vitamin E. Alles ist im Fluss

artículo científico publicado en 2009

Von Penicillin G zu tricyclischen β-Lactamen: Struktur-Wirkungs-Beziehungen

artículo científico publicado en 2006

Where are quinolones going? New agents in development

scientific article published on 01 January 2001

Why not using capillary electrophoresis in drug analysis?

artículo científico publicado en 2006

Wie kann man Resistenzen aufheben?

scholarly article by Ulrike Holzgrabe published September 2003 in Pharmazie in unserer Zeit

Wie wirkt Paracetamol? Ein weiterer Mosaikstein zum Wirkmechismus

scientific article published on 01 January 2006

XF-73 - eine neue antibakterielle Leitstruktur

artículo científico publicado en 2010

Zwei Fliegen mit einer Klappe – Platencin, ein neues Antibiotikum

artículo científico publicado en 2007

Zweifach-Angriff auf die Gyrase durch Simocyclinon

artículo científico publicado en 2010

Zwitterionic-hydrophilic interaction liquid chromatography for l-ascorbic acid 2-phosphate magnesium, a raw material in cell therapy

artículo científico publicado en 2018

Zytostatika aus dem Meer

artículo científico publicado en 2003

[A fungal substance against arteriosclerosis]

artículo científico publicado en 2004

[A new weapon against beta-3 lactamases?]

artículo científico publicado en 2006

[Antimycotics]

scientific article published on 01 January 2003

[Arrays overall]

artículo científico publicado en 2003

[Beta-lactam antibiotics as neuroprotectives]

artículo científico publicado en 2006

[Chronic obstructive pulmonary disease]

artículo científico publicado en 2007

[Editorial: Pharmazie in unserer Zeit 1/2012]

scientific article published on 01 January 2012

[Flexibility in avoiding resistance].

artículo científico publicado en 2004

[HIV therapy: and an even newer treatment--PA-457].

artículo científico publicado en 2004

[In Citation]

artículo científico publicado en 2006

[New paths to highly effective tetracyclines]

artículo científico publicado en 2005

[Paclitaxel for Alzheimer treatment].

artículo científico publicado en 2005

[Statement of accounts].

artículo científico publicado en 2008

[Synthesis, stereochemistry and analgesic action of 3,7-diazabicyclo[3.3.1] nonan-9-ones and 1,3-diazaadamantan-6-ones].

artículo científico publicado en 1989

qNMR Spectroscopy in Drug Analysis – A General View

article published in 2008

Dominio Público Uruguay está sostenido por:

Acerca de Dominio Público Uruguay

Ayuda