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Lista de obras de Simone Fulda

4-hydroperoxy-cyclophosphamide mediates caspase-independent T-cell apoptosis involving oxidative stress-induced nuclear relocation of mitochondrial apoptogenic factors AIF and EndoG.

artículo científico publicado en 2007

5-Aza-2'-deoxycytidine and IFN-gamma cooperate to sensitize for TRAIL-induced apoptosis by upregulating caspase-8.

artículo científico publicado en 2006

A Bak-dependent mitochondrial amplification step contributes to Smac mimetic/glucocorticoid-induced necroptosis

artículo científico publicado en 2016

A Perspective on Polo-Like Kinase-1 Inhibition for the Treatment of Rhabdomyosarcomas

scientific article published on 22 November 2019

A direct comparison of selective BH3-mimetics reveals BCL-XL, BCL-2 and MCL-1 as promising therapeutic targets in neuroblastoma

artículo científico publicado en 2020

A novel paradigm to trigger apoptosis in chronic lymphocytic leukemia

artículo científico publicado en 2009

A small molecule inhibits protein disulfide isomerase and triggers the chemosensitization of cancer cells

artículo científico publicado en 2014

ABT-737 promotes tBid mitochondrial accumulation to enhance TRAIL-induced apoptosis in glioblastoma cells

artículo científico publicado en 2012

APG350 induces superior clustering of TRAIL receptors and shows therapeutic antitumor efficacy independent of cross-linking via Fcγ receptors

artículo científico publicado en 2013

AT 101 induces early mitochondrial dysfunction and HMOX1 (heme oxygenase 1) to trigger mitophagic cell death in glioma cells.

artículo científico publicado en 2018

ATF4 links ER stress with reticulophagy in glioblastoma cells

artículo científico publicado en 2020

ATM inhibition enhances Auranofin-induced oxidative stress and cell death in lung cell lines

artículo científico publicado en 2020

Absence of FLICE-Inhibitory Protein Is a Novel Independent Prognostic Marker for Very Short Survival in Pancreatic Ductal Adenocarcinoma

Activation of Akt predicts poor outcome in neuroblastoma

artículo científico publicado en 2007

Activation of Mitochondria and Release of Mitochondrial Apoptogenic Factors by Betulinic Acid

artículo científico publicado en 1998

Activation of apoptosis pathways in peripheral blood lymphocytes by in vivo chemotherapy

artículo científico publicado en 2001

Activation of the CD95 (APO-1/Fas) pathway in drug- and gamma-irradiation-induced apoptosis of brain tumor cells

artículo científico publicado en 1998

Activation of the hedgehog pathway confers a poor prognosis in embryonal and fusion gene-negative alveolar rhabdomyosarcoma

article

Acute lymphoblastic leukemia cells treated with CpG oligodeoxynucleotides, IL-4 and CD40 ligand facilitate enhanced anti-leukemic CTL responses.

artículo científico publicado en 2011

Adhesion-mediated apoptosis resistance in cancer

artículo científico publicado en 2009

Alternative Cell Death Pathways and Cell Metabolism

artículo científico publicado el 21 de enero de 2013

An introduction to molecular targeted therapy of cancer

scientific article published on January 2008

Antiproliferative potential of cytostatic drugs on neuroblastoma cells in vitro

scientific article published on 01 January 1995

Apoptose

Apoptosis in hematological disorders.

artículo científico publicado en 2003

Apoptosis pathways and neuroblastoma therapy

artículo científico publicado en 2009

Apoptosis pathways and their therapeutic exploitation in pancreatic cancer

artículo científico publicado en 2009

Apoptosis pathways in neuroblastoma therapy

artículo científico publicado en 2003

Apoptosis pathways: turned on their heads?

artículo científico publicado en 2003

Apoptosis signaling in cancer stem cells

artículo científico publicado en 2009

Apoptosis signaling in tumor therapy

artículo científico publicado en 2004

Apoptotic responsiveness of the Ewing's sarcoma family of tumours to tumour necrosis factor-related apoptosis-inducing ligand (TRAIL).

artículo científico publicado en 2000

Arsenic trioxide induces Noxa-dependent apoptosis in rhabdomyosarcoma cells and synergizes with antimicrotubule drugs

artículo científico publicado en 2016

Author Correction: The landscape of genomic alterations across childhood cancers

artículo científico publicado en 2018

Autophagy activation, lipotoxicity and lysosomal membrane permeabilization synergize to promote pimozide- and loperamide-induced glioma cell death

artículo científico publicado en 2021

Autophagy and cell death

article by Simone Fulda published 31 August 2012 in Autophagy

Autophagy in Cancer Therapy

artículo científico publicado en 2017

BAG3 induction is required to mitigate proteotoxicity via selective autophagy following inhibition of constitutive protein degradation pathways

artículo científico publicado el 6 de mayo de 2013

BCL-2 selective inhibitor ABT-199 primes rhabdomyosarcoma cells to histone deacetylase inhibitor-induced apoptosis

scholarly article by Ulrike Heinicke published in June 2018

BCL-xL-selective BH3 mimetic sensitizes rhabdomyosarcoma cells to chemotherapeutics by activation of the mitochondrial pathway of apoptosis.

artículo científico publicado en 2017

Betulinic Acid for cancer treatment and prevention

artículo científico publicado en 2008

Betulinic acid as new activator of NF-kappaB: molecular mechanisms and implications for cancer therapy

artículo científico publicado en 2005

Betulinic acid induces apoptosis through a direct effect on mitochondria in neuroectodermal tumors.

artículo científico publicado en 2000

Betulinic acid triggers CD95 (APO-1/Fas)- and p53-independent apoptosis via activation of caspases in neuroectodermal tumors

artículo científico publicado en 1997

Betulinic acid-induced apoptosis in leukemia cells

artículo científico publicado en 2004

Betulinic acid: a natural product with anticancer activity

scientific article published on January 2009

Betulinic acid: a new cytotoxic agent against malignant brain-tumor cells

artículo científico publicado en 1999

Biglycan is a new high-affinity ligand for CD14 in macrophages

artículo científico publicado en 2018

Biomarker of sensitivity to PR-104 in leukemia.

artículo científico publicado en 2015

Bortezomib antagonizes microtubule-interfering drug-induced apoptosis by inhibiting G2/M transition and MCL-1 degradation

artículo científico publicado en 2013

Bortezomib primes glioblastoma, including glioblastoma stem cells, for TRAIL by increasing tBid stability and mitochondrial apoptosis

artículo científico publicado en 2011

Bortezomib primes neuroblastoma cells for TRAIL-induced apoptosis by linking the death receptor to the mitochondrial pathway

artículo científico publicado en 2011

CD95 co-stimulation blocks activation of naive T cells by inhibiting T cell receptor signaling

artículo científico publicado en 2009

CUX1: target of Akt signalling and mediator of resistance to apoptosis in pancreatic cancer.

artículo científico publicado en 2010

Caspase-8 in cancer biology and therapy

scientific article published on 25 December 2008

Cathepsin D is released after severe tissue trauma in vivo and is capable of generating C5a in vitro.

artículo científico publicado en 2012

Cell Death Pathways as Therapeutic Targets in Rhabdomyosarcoma

artículo científico publicado el 12 de enero de 2012

Cell cycle arrest in mitosis promotes interferon-induced necroptosis

scientific article published on 11 February 2019

Cell death and survival signaling in oncogenesis

artículo científico publicado el 22 de septiembre de 2010

Cell death by autophagy: emerging molecular mechanisms and implications for cancer therapy

artículo científico publicado en 2015

Cell death in hematological tumors

scientific article published on April 2009

Cell death-based treatment of glioblastoma

artículo científico publicado en 2018

Cell stress and cell death

artículo científico publicado en 2010

Cell type specific involvement of death receptor and mitochondrial pathways in drug-induced apoptosis

artículo científico publicado en 2001

Cellular stress responses: cell survival and cell death

artículo científico publicado en 2010

Characterization of sonic hedgehog as a novel NF-kappaB target gene that promotes NF-kappaB-mediated apoptosis resistance and tumor growth in vivo

artículo científico publicado en 2008

Chemosensitivity of solid tumor cellsin vitro is related to activation of the CD95 system

artículo científico publicado en 1998

Chemosensitization of glioblastoma cells by the histone deacetylase inhibitor MS275.

artículo científico publicado en 2011

Chemosensitization of rhabdomyosarcoma cells by the histone deacetylase inhibitor SAHA.

artículo científico publicado en 2014

Chloroquine overcomes resistance of lung carcinoma cells to the dual PI3K/mTOR inhibitor PI103 by lysosome-mediated apoptosis

artículo científico publicado en 2013

Co-inhibition of BET proteins and PI3Kα triggers mitochondrial apoptosis in rhabdomyosarcoma cells

scientific article published on 11 March 2020

Co-targeting of BET proteins and HDACs as a novel approach to trigger apoptosis in rhabdomyosarcoma cells

Combination of Chemotherapy and Death Ligands in Cancer Therapy

Combined Inhibition of Epigenetic Readers and Transcription Initiation Targets the EWS-ETS Transcriptional Program in Ewing Sarcoma

scientific article published on 28 January 2020

Concomitant epigenetic targeting of LSD1 and HDAC synergistically induces mitochondrial apoptosis in rhabdomyosarcoma cells

artículo científico publicado en 2017

Concomitant targeting of Hedgehog signaling and MCL-1 synergistically induces cell death in Hedgehog-driven cancer cells

scientific article published on 26 August 2019

Congenital embryonal rhabdomyosarcoma caused by heterozygous concomitant PTCH1 and PTCH2 germline mutations.

artículo científico publicado en 2017

Cooperation of betulinic acid and TRAIL to induce apoptosis in tumor cells

artículo científico publicado en 2004

Cooperative TRAIL production mediates IFNα/Smac mimetic-induced cell death in TNFα-resistant solid cancer cells

artículo científico publicado en 2016

Correction: Smac mimetic suppresses tunicamycin-induced apoptosis via resolution of ER stress

scientific article published on 25 September 2020

Cotreatment with Smac mimetics and demethylating agents induces both apoptotic and necroptotic cell death pathways in acute lymphoblastic leukemia cells

artículo científico publicado en 2016

Cotreatment with sorafenib and oleanolic acid induces reactive oxygen species-dependent and mitochondrial-mediated apoptotic cell death in hepatocellular carcinoma cells

artículo científico publicado en 2019

Critical role of mitochondria-mediated apoptosis for JNJ-26481585-induced antitumor activity in rhabdomyosarcoma

Cross talk between cell death regulation and metabolism

artículo científico

Cross-resistance of CD95- and drug-induced apoptosis as a consequence of deficient activation of caspases (ICE/Ced-3 proteases).

artículo científico publicado en 1997

Cytotoxic Capacity of IL-15-Stimulated Cytokine-Induced Killer Cells Against Human Acute Myeloid Leukemia and Rhabdomyosarcoma in Humanized Preclinical Mouse Models

artículo científico publicado en 2012

Cytotoxic drug-induced, p53-mediated upregulation of caspase-8 in tumor cells

artículo científico publicado en 2007

DNA damage response involves modulation of Ku70 and Rb functions by cyclin A1 in leukemia cells

artículo científico publicado en 2007

Death Receptor Pathways As Targets for Anticancer Therapy

Death receptor signaling in cancer therapy

artículo científico publicado en 2003

Decreased sensitivity of drug-resistant cells towards T cell cytotoxicity

artículo científico publicado en 1999

Deficient activation of the CD95 (APO-1/Fas) system in drug-resistant cells

scientific article published on 01 November 1997

Depression, comorbidities and the TNF-α system

Deregulated apoptosis signaling in core-binding factor leukemia differentiates clinically relevant, molecular marker-independent subgroups

artículo científico publicado en 2011

Diagnostic and clinical relevance of the autophago-lysosomal network in human gliomas

artículo científico publicado en 2016

Different Response of Mutant and Wildtype Rhabdomyosarcoma Toward SMO and PI3K Inhibitors

artículo científico publicado en 2018

Differential induction of apoptosis and senescence by the DNA methyltransferase inhibitors 5-azacytidine and 5-aza-2'-deoxycytidine in solid tumor cells

artículo científico publicado en 2013

Differential involvement of TAK1, RIPK1 and NF-κB signaling in Smac mimetic-induced cell death in breast cancer cells

artículo científico publicado en 2019

Differential role of RIP1 in Smac mimetic-mediated chemosensitization of neuroblastoma cells

artículo científico publicado en 2015

Dose-dependent modulation of apoptotic processes by fluoxetine in maturing neuronal cells: anin vitrostudy

Dual antitumour effect of 5-azacytidine by inducing a breakdown of resistance-mediating factors and epigenetic modulation

artículo científico publicado en 2010

Dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 synergizes with chloroquine to induce apoptosis in embryonal rhabdomyosarcoma

artículo científico publicado en 2015

ESF-EMBO Symposium "Molecular Biology and Innovative Therapies in Sarcomas of Childhood and Adolescence" Sept 29-Oct 4, Polonia Castle Pultusk, Poland

artículo científico publicado en 2013

Editorial

Editorial: Biology-Driven Targeted Therapy of Pediatric Soft-Tissue and Bone Tumors: Current Opportunities and Future Challenges

artículo científico

Effects of WR-2721 (amifostine) and its metabolite WR-1065 on the antiproliferative activity of chemotherapeutic agents on neuroblastoma cells in vitro

artículo científico publicado en 1997

Endoplasmic reticulum stress signalling - from basic mechanisms to clinical applications

scientific article published on 04 August 2018

Eribulin alone or in combination with the PLK1 inhibitor BI 6727 triggers intrinsic apoptosis in Ewing sarcoma cell lines

artículo científico publicado en 2017

Eribulin synergizes with Polo-like kinase 1 inhibitors to induce apoptosis in rhabdomyosarcoma

artículo científico publicado en 2015

Erratum: Obatoclax (GX15-070) triggers necroptosis by promoting the assembly of the necrosome on autophagosomal membranes

scholarly article published in Cell Death & Differentiation

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015.

artículo científico publicado en 2014

Evasion of apoptosis as a cellular stress response in cancer

artículo científico publicado en 2010

Exome sequencing of osteosarcoma reveals mutation signatures reminiscent of BRCA deficiency

artículo científico publicado en 2015

Exploiting apoptosis pathways for the treatment of pediatric cancers

artículo científico publicado en 2009

Exploiting death receptor signaling pathways for tumor therapy

artículo científico publicado en 2004

Exploiting inhibitor of apoptosis proteins as therapeutic targets in hematological malignancies

artículo científico publicado el 9 de enero de 2012

Exploiting mitochondrial apoptosis for the treatment of cancer

artículo científico publicado en 2010

Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease

artículo científico publicado en 2017

First EACR Conference on Cell Death in Cancer, Amsterdam, Netherlands, 26-28 January 2012.

artículo científico publicado en 2012

Functional CD95 ligand and CD95 death-inducing signaling complex in activation-induced cell death and doxorubicin-induced apoptosis in leukemic T cells.

artículo científico publicado en 2000

G-Protein coupled receptor 64 promotes invasiveness and metastasis in Ewing sarcomas through PGF and MMP1

artículo científico publicado en 2013

GDC-0941 enhances the lysosomal compartment via TFEB and primes glioblastoma cells to lysosomal membrane permeabilization and cell death

artículo científico publicado en 2012

Generation and characterization of ErbB2-CAR-engineered cytokine-induced killer cells for the treatment of high-risk soft tissue sarcoma in children

artículo científico publicado en 2017

Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes.

artículo científico publicado en 2009

HDAC inhibitors: Double edge sword for TRAIL cancer therapy?

artículo científico publicado en 2005

HIF-1-regulated glucose metabolism in the control of apoptosis signaling

scientific article published on 01 May 2008

HIF-1-regulated glucose metabolism: a key to apoptosis resistance?

artículo científico publicado en 2007

Hedgehog Inhibitors in Rhabdomyosarcoma: A Comparison of Four Compounds and Responsiveness of Four Cell Lines

artículo científico publicado en 2015

Hedgehog signaling negatively co-regulates BH3-only protein Noxa and TAp73 in TP53-mutated cells

artículo científico publicado en 2018

Herpes simplex virus thymidine kinase/ganciclovir-induced apoptosis involves ligand-independent death receptor aggregation and activation of caspases.

artículo científico publicado en 1999

Histone acetyltransferase inhibitors block neuroblastoma cell growth in vivo

artículo científico publicado en 2015

Histone deacetylase (HDAC) inhibitors and regulation of TRAIL-induced apoptosis

artículo científico publicado el 15 de febrero de 2012

Histone deacetylase inhibitors cooperate with IFN-gamma to restore caspase-8 expression and overcome TRAIL resistance in cancers with silencing of caspase-8.

artículo científico publicado en 2009

Histone deacetylase inhibitors prime medulloblastoma cells for chemotherapy-induced apoptosis by enhancing p53-dependent Bax activation.

artículo científico publicado en 2011

Histone deacetylase inhibitors sensitize glioblastoma cells to TRAIL-induced apoptosis by c-myc-mediated downregulation of cFLIP

artículo científico publicado en 2012

How to target apoptosis signaling pathways for the treatment of pediatric cancers

artículo científico publicado el 14 de febrero de 2013

How treatment affects cognitive deficits in patients with sleep disorders: methodological issues and results

scientific article published on January 2010

Hypoxia enhances the antiglioma cytotoxicity of B10, a glycosylated derivative of betulinic acid

artículo científico publicado en 2014

IAP antagonists: promising candidates for cancer therapy

artículo científico publicado en 2010

IFN-gamma reduction by tricyclic antidepressants.

artículo científico publicado en 2010

IFNgamma sensitizes for apoptosis by upregulating caspase-8 expression through the Stat1 pathway

artículo científico publicado en 2002

Identification of DR5 as a critical, NF-κB-regulated mediator of Smac-induced apoptosis

artículo científico publicado en 2013

Identification of IRF1 as critical dual regulator of Smac mimetic-induced apoptosis and inflammatory cytokine response

artículo científico publicado en 2014

Identification of RIP1 as a critical mediator of Smac mimetic-mediated sensitization of glioblastoma cells for Drozitumab-induced apoptosis

artículo científico publicado en 2015

Identification of Smac mimetics as novel substrates for p-glycoprotein

Identification of a novel oxidative stress induced cell death by Sorafenib and oleanolic acid in human hepatocellular carcinoma cells

artículo científico publicado en 2016

Identification of a novel pro-apopotic function of NF-kappaB in the DNA damage response

artículo científico publicado en 2009

Identification of a novel pro-apoptotic role of NF-κB in the regulation of TRAIL- and CD95-mediated apoptosis of glioblastoma cells

artículo científico publicado en 2012

Identification of a novel proapoptotic function of resveratrol in fat cells: SIRT1-independent sensitization to TRAIL-induced apoptosis

artículo científico publicado en 2010

Identification of a novel switch in the dominant forms of cell adhesion-mediated drug resistance in glioblastoma cells

artículo científico publicado en 2008

Identification of a novel synergistic induction of cell death by Smac mimetic and HDAC inhibitors in acute myeloid leukemia cells

artículo científico publicado en 2015

Identification of a novel synthetic lethality of combined inhibition of hedgehog and PI3K signaling in rhabdomyosarcoma

artículo científico publicado en 2015

Identification of a synergistic combination of Smac mimetic and Bortezomib to trigger cell death in B-cell non-Hodgkin lymphoma cells

artículo científico publicado en 2017

Identification of c-FLIP(L) and c-FLIP(S) as critical regulators of death receptor-induced apoptosis in pancreatic cancer cells

artículo científico publicado en 2010

Identification of flubendazole as potential anti-neuroblastoma compound in a large cell line screen

artículo científico publicado en 2015

Identification of non-canonical NF-κB signaling as a critical mediator of Smac mimetic-stimulated migration and invasion of glioblastoma cells

artículo científico publicado en 2013

Identification of synthetic lethality of PLK1 inhibition and microtubule-destabilizing drugs

artículo científico publicado en 2015

Impact of antipsychotics on cytokine production in-vitro.

artículo científico publicado en 2011

Impairment of antioxidant defense via glutathione depletion sensitizes acute lymphoblastic leukemia cells for Smac mimetic-induced cell death

artículo científico publicado en 2014

Impairment of lysosomal integrity by B10, a glycosylated derivative of betulinic acid, leads to lysosomal cell death and converts autophagy into a detrimental process.

artículo científico publicado en 2012

In vitro anticancer studies of alpha- and beta-D-glucopyranose betulin anomers

artículo científico publicado en 2010

Induction of CD95 ligand and apoptosis by doxorubicin is modulated by the redox state in chemosensitive- and drug-resistant tumor cells

article by Claudia Friesen et al published May 1999 in Cell Death & Differentiation

Inflammation, regeneration, and transformation in the pancreas: results of the Collaborative Research Center 518 (SFB 518) at the University of Ulm.

artículo científico publicado en 2011

Inhibition of TRAIL-induced apoptosis by Bcl-2 overexpression.

artículo científico publicado en 2002

Inhibition of clonogenic tumor growth: a novel function of Smac contributing to its antitumor activity

artículo científico publicado en 2005

Inhibitor of Apoptosis (IAP) Proteins: Novel Insights into the Cancer-Relevant Targets for Cell Death Induction

Inhibitor of Apoptosis (IAP) proteins as therapeutic targets for radiosensitization of human cancers

artículo científico publicado el 18 de febrero de 2012

Inhibitor of Apoptosis (IAP) proteins in hematological malignancies: molecular mechanisms and therapeutic opportunities

artículo científico publicado en 2014

Inhibitor of apoptosis proteins as targets for anticancer therapy

artículo científico publicado en 2007

Inhibitor of apoptosis proteins in hematological malignancies

artículo científico publicado en 2008

Inhibitor of apoptosis proteins in pediatric leukemia: molecular pathways and novel approaches to therapy

artículo científico publicado en 2014

Interference with the HSF1/HSP70/BAG3 Pathway Primes Glioma Cells to Matrix Detachment and BH3 Mimetic-Induced Apoptosis

artículo científico publicado en 2016

Interferons Transcriptionally Up-Regulate MLKL Expression in Cancer Cells

JNJ-26481585 primes rhabdomyosarcoma cells for chemotherapeutics by engaging the mitochondrial pathway of apoptosis

artículo científico publicado en 2015

Linear ubiquitination of cytosolic Salmonella Typhimurium activates NF-κB and restricts bacterial proliferation

artículo científico publicado en 2017

Lipoxygenase inhibitors protect acute lymphoblastic leukemia cells from ferroptotic cell death

artículo científico publicado en 2017

Loperamide, pimozide, and STF-62247 trigger autophagy-dependent cell death in glioblastoma cells

artículo científico publicado en 2018

Loss of caspase-8 expression does not correlate with MYCN amplification, aggressive disease, or prognosis in neuroblastoma

artículo científico publicado en 2006

Loss of the Chr16p11.2 ASD candidate gene leads to aberrant neuronal differentiation in the SH-SY5Y neuronal cell model

article

Macrophages induce apoptosis in proximal tubule cells

artículo científico publicado el 21 de marzo de 2003

Manatee invariants reveal functional pathways in signaling networks

artículo científico publicado en 2017

Mathematical modeling of the molecular switch of TNFR1-mediated signaling pathways applying Petri net formalism and in silico knockout analysis

scientific article published in 2022

Metabolic inhibitors sensitize for CD95 (APO-1/Fas)-induced apoptosis by down-regulating Fas-associated death domain-like interleukin 1-converting enzyme inhibitory protein expression.

artículo científico publicado en 2000

Mitochondria as therapeutic targets for the treatment of malignant disease

artículo científico publicado en 2011

Mitochondria, redox signaling and cell death in cancer

artículo científico publicado en 2016

Mitochondrial amplification of death signals determines thymidine kinase/ganciclovir-triggered activation of apoptosis.

artículo científico publicado en 2000

Modulation of TRAIL Signaling for Cancer Therapy

Modulation of TRAIL signaling for cancer therapy

artículo científico publicado en 2004

Modulation of TRAIL-induced apoptosis by HDAC inhibitors

artículo científico publicado en 2008

Modulation of apoptosis by natural products for cancer therapy

artículo científico publicado en 2010

Modulation of apoptosis signaling for cancer therapy

artículo científico publicado en 2006

Modulation of mitochondrial apoptosis by PI3K inhibitors

artículo científico

Molecular definitions of autophagy and related processes.

artículo científico publicado en 2017

Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012

artículo científico publicado en 2012

Molecular determinants of apoptosis induced by cytotoxic drugs

article

Molecular features of the cytotoxicity of an NHE inhibitor: Evidence of mitochondrial alterations, ROS overproduction and DNA damage

artículo científico publicado en 2016

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

artículo científico publicado en 2018

Molecular mechanisms of sulfasalazine-induced T-cell apoptosis

artículo científico publicado en 2002

Molecular ordering of apoptosis induced by anticancer drugs in neuroblastoma cells

artículo científico publicado en 1998

Molecular pathways: targeting death receptors and smac mimetics

artículo científico publicado en 2014

Molecular pathways: targeting inhibitor of apoptosis proteins in cancer--from molecular mechanism to therapeutic application

artículo científico publicado en 2013

Molecular targeted therapies for rhabdomyosarcoma: focus on hedgehog and apoptosis signaling

artículo científico publicado el 26 de abril de 2013

More (on) prognostic factors in chronic lymphocytic leukemia

article published in 2009

Mouse lung fibroblasts are highly susceptible to necroptosis in a reactive oxygen species-dependent manner

artículo científico publicado en 2018

MycN and IFNgamma cooperate in apoptosis of human neuroblastoma cells.

artículo científico publicado en 1998

MycN sensitizes neuroblastoma cells for drug-induced apoptosis

artículo científico publicado en 1999

MycN sensitizes neuroblastoma cells for drug-triggered apoptosis

artículo científico publicado en 2000

NF-kappaB inhibition improves the sensitivity of human glioblastoma cells to 5-aminolevulinic acid-based photodynamic therapy.

artículo científico publicado en 2010

NF-kappaB-independent sensitization of glioblastoma cells for TRAIL-induced apoptosis by proteasome inhibition.

artículo científico publicado en 2006

NF-κB contributes to Smac mimetic-conferred protection from tunicamycin-induced apoptosis

scientific article published on 01 April 2019

NF-κB is required for Smac mimetic-mediated sensitization of glioblastoma cells for γ-irradiation-induced apoptosis

artículo científico publicado en 2011

NF-κB regulates DNA double-strand break repair in conjunction with BRCA1-CtIP complexes

artículo científico publicado en 2011

NIK is required for NF-κB-mediated induction of BAG3 upon inhibition of constitutive protein degradation pathways

artículo científico publicado en 2015

NOXA as critical mediator for drug combinations in polychemotherapy

artículo científico publicado en 2012

NRAS-mutated rhabdomyosarcoma cells are vulnerable to mitochondrial apoptosis induced by co-inhibition of MEK and PI3Kα.

artículo científico publicado en 2018

Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma

scholarly article by Behrouz Hassannia et al published 1 August 2018 in Journal of Clinical Investigation

Natural killer resistance of a drug-resistant leukemia cell line, mediated by up-regulation of HLA class I expression.

artículo científico publicado en 2003

Neuroblastoma cells depend on HDAC11 for mitotic cell cycle progression and survival.

scientific article published on 02 March 2017

Newly identified c-KIT receptor tyrosine kinase ITD in childhood AML induces ligand-independent growth and is responsive to a synergistic effect of imatinib and rapamycin

artículo científico publicado en 2006

Next-generation hypomethylating agent SGI-110 primes acute myeloid leukemia cells to IAP antagonist by activating extrinsic and intrinsic apoptosis pathways

scientific article published on 12 December 2019

Next-generation personalised medicine for high-risk paediatric cancer patients - The INFORM pilot study

artículo científico publicado en 2016

Next-generation sequencing reveals a novel role of lysine-specific demethylase 1 in adhesion of rhabdomyosarcoma cells

scientific article published on 21 November 2019

Novel Promising IAP Antagonist on the Horizon for Clinical Translation

artículo científico publicado el 19 de abril de 2012

Novel insights into the synergistic interaction of Bortezomib and TRAIL: tBid provides the link

artículo científico publicado el 1 de mayo de 2011

Obatoclax (GX15-070) triggers necroptosis by promoting the assembly of the necrosome on autophagosomal membranes

artículo científico publicado en 2013

Oncogenic RAS Mutants Confer Resistance of RMS13 Rhabdomyosarcoma Cells to Oxidative Stress-Induced Ferroptotic Cell Death

artículo científico publicado en 2015

Organelle-specific mechanisms of drug-induced autophagy-dependent cell death

artículo científico publicado en 2020

Osteosarcoma cells with genetic signatures of BRCAness are susceptible to the PARP inhibitor talazoparib alone or in combination with chemotherapeutics

artículo científico publicado en 2016

PARP Inhibitors Sensitize Ewing Sarcoma Cells to Temozolomide-Induced Apoptosis via the Mitochondrial Pathway

artículo científico publicado en 2015

PI3K inhibition enhances doxorubicin-induced apoptosis in sarcoma cells

artículo científico publicado en 2012

PI3K inhibitors prime neuroblastoma cells for chemotherapy by shifting the balance towards pro-apoptotic Bcl-2 proteins and enhanced mitochondrial apoptosis

artículo científico publicado en 2010

Pan-mammalian target of rapamycin (mTOR) inhibitor AZD8055 primes rhabdomyosarcoma cells for ABT-737-induced apoptosis by down-regulating Mcl-1 protein

artículo científico publicado en 2013

Phosphatidylinositol 3-kinase inhibition broadly sensitizes glioblastoma cells to death receptor- and drug-induced apoptosis

artículo científico publicado en 2008

Plasma levels of tumor necrosis factor alpha and soluble tumor necrosis factor receptors in patients with narcolepsy

artículo científico publicado en 2006

Pleiotropic effects of sonic hedgehog on muscle satellite cells.

artículo científico publicado en 2005

Polo-like kinase 1 inhibition sensitizes neuroblastoma cells for vinca alkaloid-induced apoptosis

artículo científico publicado en 2015

Pretubulysin: a new option for the treatment of metastatic cancer

artículo científico publicado en 2014

Promises and Challenges of Smac Mimetics as Cancer Therapeutics

artículo científico publicado en 2015

Propofol--sweet dreams, but not for everyone?

artículo científico publicado en 2011

Proteasome inhibitors and Smac mimetics cooperate to induce cell death in diffuse large B-cell lymphoma by stabilizing NOXA and triggering mitochondrial apoptosis

artículo científico publicado en 2020

Proteomic screening of salt-stress-induced changes in plasma membranes of Synechocystis sp. strain PCC 6803.

artículo científico publicado en 2006

Quantitative single-molecule imaging of TNFR1 reveals zafirlukast as antagonist of TNFR1 clustering and TNFα-induced NF-ĸB signaling

artículo científico publicado en 2020

RIP1 is required for IAP inhibitor-mediated sensitization for TRAIL-induced apoptosis via a RIP1/FADD/caspase-8 cell death complex

artículo científico publicado en 2012

RIP1 is required for IAP inhibitor-mediated sensitization of childhood acute leukemia cells to chemotherapy-induced apoptosis

artículo científico publicado en 2012

RIP1 protein-dependent assembly of a cytosolic cell death complex is required for inhibitor of apoptosis (IAP) inhibitor-mediated sensitization to lexatumumab-induced apoptosis

artículo científico publicado en 2012

RIST: a potent new combination therapy for glioblastoma

artículo científico publicado en 2014

RSL3 and Erastin differentially regulate redox signaling to promote Smac mimetic-induced cell death

artículo científico publicado en 2016

Reactive oxygen species contribute toward Smac mimetic/temozolomide-induced cell death in glioblastoma cells

artículo científico publicado en 2016

Reactive oxygen species regulate Smac mimetic/TNFα-induced necroptotic signaling and cell death

artículo científico publicado en 2015

Receptor proteins in selective autophagy

artículo científico publicado en 2012

Redox Modulation and Induction of Ferroptosis as a New Therapeutic Strategy in Hepatocellular Carcinoma

artículo científico publicado en 2020

Redox regulation of Smac mimetic-induced cell death

artículo científico publicado en 2015

Regulation of Cell Death and Survival by Resveratrol: Implications for Cancer Therapy

artículo científico publicado el 1 de octubre de 2012

Regulation of TRAIL-induced apoptosis by XIAP in pancreatic carcinoma cells

artículo científico publicado en 2006

Regulation of apoptosis pathways in cancer stem cells

artículo científico publicado el 16 de marzo de 2012

Regulation of apoptosis through CD95 (APO-I/Fas) receptor-ligand interaction

artículo científico publicado en 1997

Regulation of cancer stem-like cell differentiation by Smac mimetics

artículo científico publicado en 2014

Regulation of cell death in cancer-possible implications for immunotherapy

artículo científico publicado en 2013

Regulation of cell migration, invasion and metastasis by IAP proteins and their antagonists

artículo científico publicado el 11 de marzo de 2013

Regulation of necroptosis signaling and cell death by reactive oxygen species

artículo científico publicado en 2016

Regulation of the antiapoptotic protein cFLIP by the glucocorticoid Dexamethasone in ALL cells

artículo científico publicado en 2018

Regulation of tumorigenic Wnt signaling by cyclooxygenase-2, 5-lipoxygenase and their pharmacological inhibitors: A basis for novel drugs targeting cancer cells?

artículo científico publicado en 2015

Regulatory T cells increased while IL-1β decreased during antidepressant therapy

artículo científico publicado en 2010

Repurposing anticancer drugs for targeting necroptosis

artículo científico publicado en 2018

Requirement of nuclear factor κB for Smac mimetic-mediated sensitization of pancreatic carcinoma cells for gemcitabine-induced apoptosis

artículo científico publicado en 2011

Resveratrol and derivatives for the prevention and treatment of cancer

artículo científico publicado el 6 de agosto de 2010

Resveratrol as Inhibitor of Cell Survival Signal Transduction

Resveratrol modulates DNA double-strand break repair pathways in an ATM/ATR-p53- and -Nbs1-dependent manner

artículo científico publicado en 2008

Resveratrol modulation of signal transduction in apoptosis and cell survival: A mini-review

article

Resveratrol regulates human adipocyte number and function in a Sirt1-dependent manner

artículo científico publicado en 2010

Resveratrol-mediated sensitisation to TRAIL-induced apoptosis depends on death receptor and mitochondrial signalling

artículo científico publicado en 2005

Rhabdomyosarcoma cells are susceptible to cell death by LDK378 alone or in combination with sorafenib independently of anaplastic lymphoma kinase status

artículo científico publicado en 2017

Rocaglamide and a XIAP inhibitor cooperatively sensitize TRAIL-mediated apoptosis in Hodgkin's lymphomas

artículo científico publicado en 2011

Role of Smac in cephalostatin-induced cell death

scientific article published on 19 September 2008

Role of hypoxia inducible factor-1 alpha in modulation of apoptosis resistance

artículo científico publicado en 2006

SMAC Mimetic BV6 Enables Sensitization of Resistant Tumor Cells but also Affects Cytokine-Induced Killer (CIK) Cells: A Potential Challenge for Combination Therapy

artículo científico publicado en 2014

STF-62247 and pimozide induce autophagy and autophagic cell death in mouse embryonic fibroblasts

scientific article published on 20 January 2020

Safety and tolerability of TRAIL receptor agonists in cancer treatment

artículo científico publicado en 2015

Second EACR Conference on Cell Death in Cancer, Amsterdam, The Netherlands, 30 January-1 February 2014.

artículo científico publicado en 2014

Selective BH3-mimetics targeting BCL-2, BCL-XL or MCL-1 induce severe mitochondrial perturbations

scholarly article by Kristina Henz published in July 2018

Selective and nonselective toxicity of TRAIL/Apo2L combined with chemotherapy in human bone tumour cells vs. normal human cells

artículo científico publicado en 2003

Sensitization for anticancer drug-induced apoptosis by betulinic Acid

artículo científico publicado en 2005

Sensitization for anticancer drug-induced apoptosis by the chemopreventive agent resveratrol

artículo científico publicado en 2004

Sensitization for death receptor- or drug-induced apoptosis by re-expression of caspase-8 through demethylation or gene transfer

artículo científico publicado en 2001

Sensitization for gamma-irradiation-induced apoptosis by second mitochondria-derived activator of caspase

artículo científico publicado en 2005

Sensitization for tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by the chemopreventive agent resveratrol

artículo científico publicado en 2004

Sensitization of acute lymphoblastic leukemia cells for LCL161-induced cell death by targeting redox homeostasis

artículo científico publicado en 2016

Sensitization of neuroblastoma cells for TRAIL-induced apoptosis by NF-kappaB inhibition

artículo científico publicado en 2009

Sensitization of pancreatic carcinoma cells for γ-irradiation-induced apoptosis by XIAP inhibition

artículo científico publicado en 2007

Sequential dosing in chemosensitization: targeting the PI3K/Akt/mTOR pathway in neuroblastoma

artículo científico publicado en 2013

Shifting the balance of mitochondrial apoptosis: therapeutic perspectives

artículo científico publicado el 8 de octubre de 2012

Side-by-side comparison of BH3-mimetics identifies MCL-1 as a key therapeutic target in AML

scientific article published on 04 December 2019

Signal Transduction Therapy Targeting Apoptosis Pathways in Cancers

Signaling through death receptors in cancer therapy

artículo científico publicado en 2004

Single-molecule imaging reveals the oligomeric state of functional TNFα-induced plasma membrane TNFR1 clusters in cells

artículo científico publicado en 2020

Smac Mimetic-Induced Upregulation of CCL2/MCP-1 Triggers Migration and Invasion of Glioblastoma Cells and Influences the Tumor Microenvironment in a Paracrine Manner

artículo científico publicado en 2015

Smac Mimetics to Therapeutically Target IAP Proteins in Cancer

artículo científico publicado en 2017

Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo

artículo científico publicado en 2002

Smac mimetic and demethylating agents synergistically trigger cell death in acute myeloid leukemia cells and overcome apoptosis resistance by inducing necroptosis

artículo científico publicado en 2013

Smac mimetic and glucocorticoids synergize to induce apoptosis in childhood ALL by promoting ripoptosome assembly

artículo científico publicado en 2014

Smac mimetic and oleanolic acid synergize to induce cell death in human hepatocellular carcinoma cells

artículo científico publicado en 2015

Smac mimetic bypasses apoptosis resistance in FADD- or caspase-8-deficient cells by priming for tumor necrosis factor α-induced necroptosis

artículo científico publicado en 2011

Smac mimetic induces an early wave of gene expression via NF-κB and AP-1 and a second wave via TNFR1 signaling

artículo científico publicado en 2018

Smac mimetic induces cell death in a large proportion of primary acute myeloid leukemia samples, which correlates with defined molecular markers

scientific article published on 02 July 2016

Smac mimetic primes apoptosis-resistant acute myeloid leukaemia cells for cytarabine-induced cell death by triggering necroptosis

artículo científico publicado en 2013

Smac mimetic promotes glioblastoma cancer stem-like cell differentiation by activating NF-κB.

artículo científico

Smac mimetic sensitizes glioblastoma cells to Temozolomide-induced apoptosis in a RIP1- and NF-κB-dependent manner.

artículo científico publicado en 2012

Smac mimetic sensitizes renal cell carcinoma cells to interferon-α-induced apoptosis

artículo científico publicado en 2016

Smac mimetic suppresses tunicamycin-induced apoptosis via resolution of ER stress

Smac mimetic triggers necroptosis in pancreatic carcinoma cells when caspase activation is blocked

artículo científico publicado en 2016

Smac mimetic-induced upregulation of interferon-β sensitizes glioblastoma to temozolomide-induced cell death

artículo científico publicado en 2015

Smac mimetics and TRAIL cooperate to induce MLKL-dependent necroptosis in Burkitt's lymphoma cell lines

artículo científico publicado en 2021

Smac mimetics and type II interferon synergistically induce necroptosis in various cancer cell lines

artículo científico publicado en 2017

Smac mimetics as IAP antagonists

artículo científico

Small molecule XIAP inhibitors cooperate with TRAIL to induce apoptosis in childhood acute leukemia cells and overcome Bcl-2-mediated resistance

scientific article published on 25 November 2008

Small molecule XIAP inhibitors enhance TRAIL-induced apoptosis and antitumor activity in preclinical models of pancreatic carcinoma

artículo científico publicado en 2009

Small molecule XIAP inhibitors sensitize childhood acute leukemia cells for CD95-induced apoptosis

artículo científico publicado en 2010

Small-molecule XIAP inhibitors enhance gamma-irradiation-induced apoptosis in glioblastoma

artículo científico publicado en 2009

Sorafenib inhibits therapeutic induction of necroptosis in acute leukemia cells

artículo científico publicado en 2017

Sorafenib tosylate inhibits directly necrosome complex formation and protects in mouse models of inflammation and tissue injury.

artículo científico publicado en 2017

Specific interactions of BCL-2 family proteins mediate sensitivity to BH3-mimetics in diffuse large B-cell lymphoma

scientific article published on 10 October 2019

Structure-activity studies on N-Substituted tranylcypromine derivatives lead to selective inhibitors of lysine specific demethylase 1 (LSD1) and potent inducers of leukemic cell differentiation

artículo científico publicado en 2017

Suberoylanilide hydroxamic acid synergistically enhances the antitumor activity of etoposide in Ewing sarcoma cell lines

artículo científico publicado en 2015

Survivin as a prognostic/predictive marker and molecular target in cancer therapy

artículo científico

Synergistic induction of apoptosis by a polo-like kinase 1 inhibitor and microtubule-interfering drugs in Ewing sarcoma cells

artículo científico publicado en 2015

Synergistic interaction of Smac mimetic and IFNα to trigger apoptosis in acute myeloid leukemia cells

artículo científico publicado en 2014

Synthetic lethal interaction between PI3K/Akt/mTOR and Ras/MEK/ERK pathway inhibition in rhabdomyosarcoma

artículo científico publicado en 2013

Synthetic lethality by co-targeting mitochondrial apoptosis and PI3K/Akt/mTOR signaling

artículo científico

TNF-alpha, soluble TNF receptor and interleukin-6 plasma levels in the general population

artículo científico publicado en 2006

TRAIL enhances thymidine kinase/ganciclovir gene therapy of neuroblastoma cells

artículo científico publicado en 2002

TRAIL induced survival and proliferation in cancer cells resistant towards TRAIL-induced apoptosis mediated by NF-kappaB.

artículo científico publicado en 2003

TRAIL-induced apoptosis is preferentially mediated via TRAIL receptor 1 in pancreatic carcinoma cells and profoundly enhanced by XIAP inhibitors

artículo científico publicado en 2010

Targeting Apoptosis Signaling Pathways for Anticancer Therapy

artículo científico publicado el 27 de agosto de 2011

Targeting BCL-2 proteins in pediatric cancer: Dual inhibition of BCL-XL and MCL-1 leads to rapid induction of intrinsic apoptosis

scientific article published on 04 March 2020

Targeting IAP proteins for therapeutic intervention in cancer

artículo científico

Targeting IAP proteins in combination with radiotherapy

artículo científico publicado en 2015

Targeting Inhibitor of Apoptosis Proteins for Cancer Therapy: A Double-Edge Sword?

Targeting X-linked inhibitor of apoptosis protein to increase the efficacy of endoplasmic reticulum stress-induced apoptosis for melanoma therapy.

artículo científico publicado en 2010

Targeting XIAP Bypasses Bcl-2-Mediated Resistance to TRAIL and Cooperates with TRAIL to Suppress Pancreatic Cancer Growth In vitro and In vivo

artículo científico publicado en 2008

Targeting aberrant PI3K/Akt activation by PI103 restores sensitivity to TRAIL-induced apoptosis in neuroblastoma.

artículo científico publicado en 2011

Targeting apoptosis for anticancer therapy

artículo científico

Targeting apoptosis pathways in cancer therapy

artículo científico publicado en 2004

Targeting apoptosis pathways in childhood malignancies

artículo científico publicado el 30 de octubre de 2010

Targeting apoptosis resistance in rhabdomyosarcoma

artículo científico publicado en 2008

Targeting apoptosis signaling in pancreatic cancer

artículo científico publicado en 2011

Targeting autophagy for the treatment of cancer

artículo científico publicado en 2018

Targeting c-FLICE-like inhibitory protein (CFLAR) in cancer

artículo científico publicado el 20 de diciembre de 2012

Targeting extrinsic apoptosis in cancer: Challenges and opportunities

artículo científico publicado en 2015

Targeting ferroptosis in rhabdomyosarcoma cells

scientific article published on 04 July 2019

Targeting inhibitor of apoptosis proteins (IAPs) for cancer therapy

artículo científico publicado en 2008

Targeting inhibitor of apoptosis proteins (IAPs) for diagnosis and treatment of human diseases

artículo científico publicado en 2006

Targeting inhibitor of apoptosis proteins by Smac mimetic elicits cell death in poor prognostic subgroups of chronic lymphocytic leukemia

artículo científico publicado en 2015

Targeting mitochondria for cancer therapy

artículo científico publicado en 2010

Targeting mitochondrial apoptosis by betulinic acid in human cancers

artículo científico publicado en 2009

Targeting of XIAP combined with systemic mesenchymal stem cell-mediated delivery of sTRAIL ligand inhibits metastatic growth of pancreatic carcinoma cells

artículo científico publicado en 2010

Targeting redox homeostasis in rhabdomyosarcoma cells: GSH-depleting agents enhance auranofin-induced cell death

artículo científico publicado en 2017

The CD95 (APO-1/Fas) system mediates drug-induced apoptosis in neuroblastoma cells

artículo científico publicado en 1997

The IRE1 and PERK arms of the unfolded protein response promote survival of rhabdomyosarcoma cells

artículo científico publicado en 2020

The PI3K/Akt/mTOR pathway as therapeutic target in neuroblastoma

artículo científico publicado en 2009

The SMAC mimetic BV6 sensitizes colorectal cancer cells to ionizing radiation by interfering with DNA repair processes and enhancing apoptosis

artículo científico publicado en 2015

The Smac Mimetic BV6 Improves NK Cell-Mediated Killing of Rhabdomyosarcoma Cells by Simultaneously Targeting Tumor and Effector Cells

artículo científico publicado en 2017

The cytotoxic potential of interleukin-15-stimulated cytokine-induced killer cells against leukemia cells

artículo científico publicado en 2011

The dark side of TRAIL signaling

artículo científico publicado en 2013

The dual PI3K/mTOR inhibitor NVP-BEZ235 and chloroquine synergize to trigger apoptosis via mitochondrial-lysosomal cross-talk

artículo científico publicado en 2012

The first European interdisciplinary ewing sarcoma research summit

artículo científico publicado en 2012

The landscape of genomic alterations across childhood cancers

artículo científico publicado en 2018

The long non-coding RNA HOTAIRM1 promotes tumor aggressiveness and radiotherapy resistance in glioblastoma

artículo científico publicado en 2021

The mechanism of necroptosis in normal and cancer cells

artículo científico publicado en 2013

The novel dual BET/HDAC inhibitor TW09 mediates cell death by mitochondrial apoptosis in rhabdomyosarcoma cells

artículo científico publicado en 2020

The pleiotropic profile of the indirubin derivative 6BIO overcomes TRAIL resistance in cancer

artículo científico publicado en 2014

The pyridinylfuranopyrimidine inhibitor, PI-103, chemosensitizes glioblastoma cells for apoptosis by inhibiting DNA repair.

artículo científico publicado en 2009

The role of survivin for radiation oncology: moving beyond apoptosis inhibition

artículo científico publicado en 2011

Therapeutic Modulation of Apoptosis in Cancer Therapy

Therapeutic exploitation of apoptosis and autophagy for glioblastoma

artículo científico publicado en 2010

Therapeutic exploitation of necroptosis for cancer therapy

artículo científico publicado en 2014

Therapeutic modulation of death receptor- or drug-mediated apoptosis

article published in 2002

Therapeutic opportunities based on caspase modulation

artículo científico publicado en 2017

Therapeutic opportunities for counteracting apoptosis resistance in childhood leukaemia

scientific article published on May 2009

Therapeutic targeting of necroptosis by Smac mimetic bypasses apoptosis resistance in acute myeloid leukemia cells

artículo científico publicado en 2016

Thioredoxin inhibitor PX-12 induces mitochondria-mediated apoptosis in acute lymphoblastic leukemia cells

artículo científico publicado en 2020

Thirty-eight-negative kinase 1 (TNK1) facilitates TNFα-induced apoptosis by blocking NF-κB activation

scholarly article by N Azoitei et al published 30 April 2007 in Oncogene

Transcriptomic signatures of neuronal differentiation and their association with risk genes for autism spectrum and related neuropsychiatric disorders.

artículo científico publicado en 2016

Tumor resistance to apoptosis

artículo científico publicado en 2009

Tumor-necrosis-factor-related apoptosis-inducing ligand (TRAIL).

artículo científico

USP22 controls necroptosis by regulating receptor-interacting protein kinase 3 ubiquitination

artículo científico publicado en 2020

USP9X stabilizes XIAP to regulate mitotic cell death and chemoresistance in aggressive B-cell lymphoma

artículo científico publicado en 2016

Ubiquitylation in immune disorders and cancer: from molecular mechanisms to therapeutic implications

artículo científico

Variants of the CNTNAP2 5' promoter as risk factors for autism spectrum disorders: a genetic and functional approach

artículo científico publicado en 2014

Visualizing ubiquitination in mammalian cells

artículo científico publicado en 2019

Zellbiologie

scholarly article

cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production

scientific journal article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

artículo científico publicado en 2016

Guía para el uso y la interpretación de ensayos para el seguimiento de la autofagia (4ª edición)

artículo científico