Lista de obras - Manuela Baccarini - Dominio Público Uruguay

"RAF" neighborhood: protein-protein interaction in the Raf/Mek/Erk pathway

artículo científico publicado en 2014

A Mek1-Mek2 heterodimer determines the strength and duration of the Erk signal

artículo científico publicado en 2009

A balance between Raf-1 and Fas expression sets the pace of erythroid differentiation

artículo científico publicado en 2006

A cell-autonomous tumour suppressor role of RAF1 in hepatocarcinogenesis

artículo científico publicado en 2016

A fast and objective assay for cell mediated intra- and extracellular killing of Leishmania promastigotes

artículo científico publicado en 1986

A radiolabel release microassay for phagocytic killing of Candida albicans

artículo científico publicado en 1982

Activating mutations in MEK1 enhance homodimerization and promote tumorigenesis

artículo científico publicado en 2018

Activation of bcl-2 suppressible 40 and 44 kDa p38-like kinases during apoptosis of early and late B lymphocytic cell lines

artículo científico publicado en 1998

Alike but Different: RAF Paralogs and Their Signaling Outputs

artículo científico

An ERK-Dependent Feedback Mechanism Prevents Hematopoietic Stem Cell Exhaustion.

artículo científico publicado en 2018

An old kinase on a new path: Raf and apoptosis

artículo científico publicado en 2002

Angiogenic sprouting requires the fine tuning of endothelial cell cohesion by the Raf-1/Rok-α complex

artículo científico publicado en 2011

B-Raf and C-Raf are required for melanocyte stem cell self-maintenance

scientific journal article

B-Raf is required for ERK activation and tumor progression in a mouse model of pancreatic beta-cell carcinogenesis.

artículo científico publicado en 2008

BRAF inhibitors suppress apoptosis through off-target inhibition of JNK signaling

artículo científico publicado en 2013

Bacterially expressed murine CSF-1 possesses agonistic activity in its monomeric form

artículo científico publicado en 1993

C-Raf is required for the initiation of lung cancer by K-Ras(G12D).

artículo científico publicado en 2011

Cardiac-specific disruption of the c-raf-1 gene induces cardiac dysfunction and apoptosis

artículo científico publicado en 2004

Cellular mechanisms underlying the adjuvant activity of Candida albicans in a mouse lymphoma model.

artículo científico publicado en 1982

Central role for type I interferons and Tyk2 in lipopolysaccharide-induced endotoxin shock

artículo científico publicado en 2003

Colony stimulating factor-1 (CSF-1) stimulates temperature dependent phosphorylation and activation of the RAF-1 proto-oncogene product

artículo científico publicado en 1990

Combination of Hypoglycemia and Metformin Impairs Tumor Metabolic Plasticity and Growth by Modulating the PP2A-GSK3β-MCL-1 Axis

artículo científico publicado en 2019

Combined effects of cyclophosphamide and thymostimulin treatment on the in vitro natural killer and candidacidal activity of murine spleen cells

artículo científico publicado en 1984

Comparison between natural reactivity (NR) against Candida albicans and natural killer (NK) activity against YAC-1 tumour cells

artículo científico publicado el 1 de enero de 1983

Conservation of Salmonella infection mechanisms in plants and animals

artículo científico publicado en 2011

Constitutive activation of the MAPK pathway mediates v-fes-induced mitogenesis in murine macrophages.

artículo científico publicado en 2000

Cooperative effects of colony-stimulating factor 1 and recombinant interleukin 2 on proliferation and induction of cytotoxicity of macrophage precursors generated from mouse bone marrow cell cultures

artículo científico publicado en 1989

Coordinate expression of the lineage-specific growth factor colony-stimulating factor (CSF)-1 and its receptor selectively promotes macrophage maturation during differentiation of multipotential progenitor cells.

artículo científico publicado en 1994

Correlation between in vivo and in vitro studies of modulation of resistance to experimental Candida albicans infection by cyclophosphamide in mice

artículo científico publicado en 1983

Deciphering signaling pathways in vivo: the Ras/Raf/MEK/ERK cascade.

artículo científico publicado en 2010

Deciphering the RAS/ERK pathway in vivo

artículo científico publicado en 2017

Dephosphorylation of Ser-259 regulates Raf-1 membrane association

artículo científico publicado en 2001

Distinct mechanisms target stress and extracellular signal-activated kinase 1 and Jun N-terminal kinase during infection of macrophages with Salmonella.

artículo científico publicado en 1999

EGFR-ras-raf signaling in epidermal stem cells: roles in hair follicle development, regeneration, tissue remodeling and epidermal cancers

artículo científico

ERK and beyond: insights from B-Raf and Raf-1 conditional knockouts

artículo científico publicado en 2006

ERK signaling, but not c-Raf, is required for gonadotropin-releasing hormone (GnRH)-induced regulation of Nur77 in pituitary gonadotropes

artículo científico publicado en 2011

Editorial overview: Cell regulation

Effect of human recombinant IL-2 on murine macrophage precursors. Involvement of a receptor distinct from the p55 (Tac) protein

scientific article published on 01 January 1989

Efficient natural defense mechanisms against Listeria monocytogenes in T and B cell-deficient allogeneic bone marrow radiation chimeras. Preactivated macrophages are the main effector cells in an early phase after bone marrow transfer.

artículo científico publicado en 1989

Embryonic lethality and fetal liver apoptosis in mice lacking the c-raf-1 gene

artículo científico publicado en 2001

Enhancement of natural killer cell activity in mice by treatment with a thymic factor

artículo científico publicado en 1984

Epidermal RAF prevents allergic skin disease

artículo científico publicado en 2016

Epidermal growth factor stimulates phosphorylation of RAF-1 independently of receptor autophosphorylation and internalization.

artículo científico publicado en 1991

Erratum: Ras and Raf pathways in epidermis development and carcinogenesis

article

Essential role of B-Raf in ERK activation during extraembryonic development

artículo científico publicado en 2006

Essential role of B-Raf in oligodendrocyte maturation and myelination during postnatal central nervous system development

artículo científico publicado en 2008

Essential, non-redundant roles of B-Raf and Raf-1 in Ras-driven skin tumorigenesis

artículo científico publicado en 2012

Fibronectin-tissue transglutaminase matrix rescues RGD-impaired cell adhesion through syndecan-4 and beta1 integrin co-signaling

artículo científico publicado en 2008

From autoinhibition to inhibition in trans: the Raf-1 regulatory domain inhibits Rok-alpha kinase activity

artículo científico publicado en 2009

Functional heterogeneity of macrophage precursor cells from spleen of Leishmania donovani-infected and untreated mice

artículo científico publicado en 1989

Functional heterogeneity of murine macrophage precursor cells from spleen and bone marrow

scientific article published on 01 September 1986

Growth phase-regulated induction of Salmonella-induced macrophage apoptosis correlates with transient expression of SPI-1 genes

artículo científico publicado en 1999

Heterogeneous activity of immature and mature cells of the murine monocyte-macrophage lineage derived from different anatomical districts against yeast-phase Candida albicans

artículo científico publicado en 1986

Host factor I, Hfq, binds to Escherichia coli ompA mRNA in a growth rate-dependent fashion and regulates its stability.

artículo científico publicado en 1998

IFN-gamma/lipopolysaccharide activation of macrophages is associated with protein kinase C-dependent down-modulation of the colony-stimulating factor-1 receptor

artículo científico publicado en 1992

In vitro natural cell-mediated cytotoxicity against Candida albicans: macrophage precursors as effector cells

artículo científico publicado en 1985

Involvement of the protein tyrosine phosphatase SHP-1 in Ras-mediated activation of the mitogen-activated protein kinase pathway.

artículo científico publicado en 1996

Keratinocyte-specific stat3 heterozygosity impairs development of skin tumors in human papillomavirus 8 transgenic mice.

artículo científico publicado en 2010

Killing of yeast, germ-tube and mycelial forms of Candida albicans by murine effectors as measured by a radiolabel release microassay

artículo científico publicado en 1985

Knock-in(g) RAF for a loop

artículo científico publicado en 2015

Lipopolysaccharide induces activation of the Raf-1/MAP kinase pathway. A putative role for Raf-1 in the induction of the IL-1 beta and the TNF-alpha genes

artículo científico publicado en 1994

Lipopolysaccharide induces jun N-terminal kinase activation in macrophages by a novel Cdc42/Rac-independent pathway involving sequential activation of protein kinase C zeta and phosphatidylcholine-dependent phospholipase C.

artículo científico publicado en 2000

Listeria monocytogenes infection rewires host metabolism with regulatory input from type I interferons

artículo científico publicado en 2021

Liver-associated macrophage precursor cells proliferate under impairment of regular hemopoiesis

artículo científico publicado en 1988

Liver-associated macrophage precursors as natural cytotoxic effectors againstCandida albicans and Yac-1 cells

scholarly article by Thomas Decker et al published 1986 in European Journal of Immunology

MEK1 is required for PTEN membrane recruitment, AKT regulation, and the maintenance of peripheral tolerance

artículo científico publicado en 2013

MEK1 is required for the development of NRAS-driven leukemia

artículo científico publicado en 2016

Macrophage function in murine allogeneic bone marrow radiation chimeras in the early phase after transplantation.

artículo científico publicado en 1989

Modulation of polymorphonucleate-mediated cytotoxicity against Candida albicans by thymosin alpha 1.

artículo científico publicado en 1985

Natural cell-mediated cytotoxicity against Candida albicans induced by cyclophosphamide: nature of the in vitro cytotoxic effector.

artículo científico publicado en 1983

Opposite effects of different doses of MCSF on ERK phosphorylation and cell proliferation in macrophages

artículo científico publicado en 2002

Organ-associated macrophage precursor activity: isolation of candidacidal and tumoricidal effectors from the spleens of cyclophosphamide-treated mice

artículo científico publicado en 1986

Pancreatic β-cell Raf-1 is required for glucose tolerance, insulin secretion, and insulin 2 transcription

scientific journal article

Partner exchange: protein-protein interactions in the Raf pathway

artículo científico publicado en 2010

Phagocytic killing of Candida albicans by different murine effector cells

artículo científico publicado en 1983

Protective role of Raf-1 in Salmonella-induced macrophage apoptosis

artículo científico publicado en 2001

RAF dimers control vascular permeability and cytoskeletal rearrangements at endothelial cell-cell junctions

scientific article published on 18 March 2019

RAF proteins exert both specific and compensatory functions during tumour progression of NRAS-driven melanoma.

artículo científico publicado en 2017

RAF1/BRAF dimerization integrates the signal from RAS to ERK and ROKα.

artículo científico publicado en 2017

RASSF1A elicits apoptosis through an MST2 pathway directing proapoptotic transcription by the p73 tumor suppressor protein

artículo científico publicado en 2007

RKIP regulates MAP kinase signaling in cells with defective B-Raf activity

artículo científico publicado en 2013

Raf Kinases Are Essential for Phosphate Induction of ERK1/2 Phosphorylation in Hypertrophic Chondrocytes and Normal Endochondral Bone Development.

artículo científico publicado en 2017

Raf kinase signaling functions in sensory neuron differentiation and axon growth in vivo

artículo científico publicado en 2007

Raf kinases in cancer-roles and therapeutic opportunities

artículo científico publicado en 2011

Raf protects against colitis by promoting mouse colon epithelial cell survival through NF-kappaB

artículo científico publicado en 2008

Raf-1 addiction in Ras-induced skin carcinogenesis

artículo científico publicado en 2009

Raf-1 and B-Raf proteins have similar regional distributions but differential subcellular localization in adult rat brain

scientific journal article

Raf-1 antagonizes erythroid differentiation by restraining caspase activation

artículo científico publicado en 2002

Raf-1 regulates Rho signaling and cell migration

artículo científico publicado en 2005

Raf-1 sets the threshold of Fas sensitivity by modulating Rok-alpha signaling

scientific journal article

Raf-1-associated Protein Phosphatase 2A as a Positive Regulator of Kinase Activation

artículo científico publicado en 2000

Ras and Raf pathways in epidermis development and carcinogenesis

artículo científico publicado en 2010

Ras-dependent and -independent pathways target the mitogen-activated protein kinase network in macrophages.

artículo científico publicado en 1995

Ras/MAP kinase-dependent and -independent signaling pathways target distinct ternary complex factors

artículo científico publicado en 1994

Regulation of cytosolic phospholipase A2 in arachidonic acid release of rat-liver macrophages

scientific article published on 01 January 1997

Relationships among tumor load, route of tumor inoculation, and response to immunochemotherapy in a murine lymphoma model

article

Role of cytosolic phospholipase A2 in arachidonic acid release of rat-liver macrophages: regulation by Ca2+ and phosphorylation

artículo científico publicado en 1995

Role of the kinase MST2 in suppression of apoptosis by the proto-oncogene product Raf-1.

artículo científico publicado en 2004

Salmonella typhimurium and lipopolysaccharide stimulate extracellularly regulated kinase activation in macrophages by a mechanism involving phosphatidylinositol 3-kinase and phospholipase D as novel intermediates.

artículo científico publicado en 1999

Salmonella-induced caspase-2 activation in macrophages: a novel mechanism in pathogen-mediated apoptosis

artículo científico publicado en 2000

Second nature: biological functions of the Raf-1 "kinase"

artículo científico publicado en 2005

Selective requirement of PI3K/PDK1 signaling for Kras oncogene-driven pancreatic cell plasticity and cancer

artículo científico publicado en 2013

Skin tumorigenesis stimulated by Raf inhibitors relies upon Raf functions that are dependent and independent of ERK.

artículo científico publicado en 2013

Sorafenib suppresses JNK-dependent apoptosis through inhibition of ZAK.

artículo científico publicado en 2013

Suppression of growth factor-mediated MAP kinase activation by v-raf in macrophages: a putative role for the MKP-1 phosphatase

artículo científico publicado en 1995

Targets of Raf in tumorigenesis

artículo científico publicado en 2010

The Raf-1 kinase associates with vimentin kinases and regulates the structure of vimentin filaments

artículo científico publicado en 2000

The dimer-dependent catalytic activity of RAF family kinases is revealed through characterizing their oncogenic mutants

scholarly article by Jimin Yuan published in June 2018

The response of gamma interferon activation factor is under developmental control in cells of the macrophage lineage

artículo científico publicado en 1993

The role of the peritoneal cavity in successful treatment of a murine lymphoma with chemotherapy and non-specific immunostimulation

scientific article published on 01 January 1982

Transient activation of RAF-1, MEK, and ERK2 coincides kinetically with ternary complex factor phosphorylation and immediate-early gene promoter activity in vivo

artículo científico publicado en 1994

Upregulation of lineage specific receptors and ligands in multipotential progenitor cells is part of an endogenous program of differentiation

artículo científico publicado en 1993

c-Raf promotes angiogenesis during normal growth plate maturation

artículo científico publicado en 2015

c-Raf, but not B-Raf, is essential for development of K-Ras oncogene-driven non-small cell lung carcinoma

artículo científico publicado en 2011

p38 links RAS to GATA2.

artículo científico publicado en 2014

v-raf confers CSF-1 independent growth to a macrophage cell line and leads to immediate early gene expression without MAP-kinase activation

artículo científico publicado en 1993

Lista de obras de Manuela Baccarini

"RAF" neighborhood: protein-protein interaction in the Raf/Mek/Erk pathway

A Mek1-Mek2 heterodimer determines the strength and duration of the Erk signal

A balance between Raf-1 and Fas expression sets the pace of erythroid differentiation

A cell-autonomous tumour suppressor role of RAF1 in hepatocarcinogenesis

A fast and objective assay for cell mediated intra- and extracellular killing of Leishmania promastigotes

A radiolabel release microassay for phagocytic killing of Candida albicans

Activating mutations in MEK1 enhance homodimerization and promote tumorigenesis

Activation of bcl-2 suppressible 40 and 44 kDa p38-like kinases during apoptosis of early and late B lymphocytic cell lines

Alike but Different: RAF Paralogs and Their Signaling Outputs

An ERK-Dependent Feedback Mechanism Prevents Hematopoietic Stem Cell Exhaustion.

An old kinase on a new path: Raf and apoptosis

Angiogenic sprouting requires the fine tuning of endothelial cell cohesion by the Raf-1/Rok-α complex

B-Raf and C-Raf are required for melanocyte stem cell self-maintenance

B-Raf is required for ERK activation and tumor progression in a mouse model of pancreatic beta-cell carcinogenesis.

BRAF inhibitors suppress apoptosis through off-target inhibition of JNK signaling

Bacterially expressed murine CSF-1 possesses agonistic activity in its monomeric form

C-Raf is required for the initiation of lung cancer by K-Ras(G12D).

Cardiac-specific disruption of the c-raf-1 gene induces cardiac dysfunction and apoptosis

Cellular mechanisms underlying the adjuvant activity of Candida albicans in a mouse lymphoma model.

Central role for type I interferons and Tyk2 in lipopolysaccharide-induced endotoxin shock

Colony stimulating factor-1 (CSF-1) stimulates temperature dependent phosphorylation and activation of the RAF-1 proto-oncogene product

Combination of Hypoglycemia and Metformin Impairs Tumor Metabolic Plasticity and Growth by Modulating the PP2A-GSK3β-MCL-1 Axis

Combined effects of cyclophosphamide and thymostimulin treatment on the in vitro natural killer and candidacidal activity of murine spleen cells

Comparison between natural reactivity (NR) against Candida albicans and natural killer (NK) activity against YAC-1 tumour cells

Conservation of Salmonella infection mechanisms in plants and animals

Constitutive activation of the MAPK pathway mediates v-fes-induced mitogenesis in murine macrophages.

Cooperative effects of colony-stimulating factor 1 and recombinant interleukin 2 on proliferation and induction of cytotoxicity of macrophage precursors generated from mouse bone marrow cell cultures

Coordinate expression of the lineage-specific growth factor colony-stimulating factor (CSF)-1 and its receptor selectively promotes macrophage maturation during differentiation of multipotential progenitor cells.

Correlation between in vivo and in vitro studies of modulation of resistance to experimental Candida albicans infection by cyclophosphamide in mice

Deciphering signaling pathways in vivo: the Ras/Raf/MEK/ERK cascade.

Deciphering the RAS/ERK pathway in vivo

Dephosphorylation of Ser-259 regulates Raf-1 membrane association

Distinct mechanisms target stress and extracellular signal-activated kinase 1 and Jun N-terminal kinase during infection of macrophages with Salmonella.

EGFR-ras-raf signaling in epidermal stem cells: roles in hair follicle development, regeneration, tissue remodeling and epidermal cancers

ERK and beyond: insights from B-Raf and Raf-1 conditional knockouts

ERK signaling, but not c-Raf, is required for gonadotropin-releasing hormone (GnRH)-induced regulation of Nur77 in pituitary gonadotropes

Editorial overview: Cell regulation

Effect of human recombinant IL-2 on murine macrophage precursors. Involvement of a receptor distinct from the p55 (Tac) protein

Efficient natural defense mechanisms against Listeria monocytogenes in T and B cell-deficient allogeneic bone marrow radiation chimeras. Preactivated macrophages are the main effector cells in an early phase after bone marrow transfer.

Embryonic lethality and fetal liver apoptosis in mice lacking the c-raf-1 gene

Enhancement of natural killer cell activity in mice by treatment with a thymic factor

Epidermal RAF prevents allergic skin disease

Epidermal growth factor stimulates phosphorylation of RAF-1 independently of receptor autophosphorylation and internalization.

Erratum: Ras and Raf pathways in epidermis development and carcinogenesis

Essential role of B-Raf in ERK activation during extraembryonic development

Essential role of B-Raf in oligodendrocyte maturation and myelination during postnatal central nervous system development

Essential, non-redundant roles of B-Raf and Raf-1 in Ras-driven skin tumorigenesis

Fibronectin-tissue transglutaminase matrix rescues RGD-impaired cell adhesion through syndecan-4 and beta1 integrin co-signaling

From autoinhibition to inhibition in trans: the Raf-1 regulatory domain inhibits Rok-alpha kinase activity

Functional heterogeneity of macrophage precursor cells from spleen of Leishmania donovani-infected and untreated mice

Functional heterogeneity of murine macrophage precursor cells from spleen and bone marrow

Growth phase-regulated induction of Salmonella-induced macrophage apoptosis correlates with transient expression of SPI-1 genes

Heterogeneous activity of immature and mature cells of the murine monocyte-macrophage lineage derived from different anatomical districts against yeast-phase Candida albicans

Host factor I, Hfq, binds to Escherichia coli ompA mRNA in a growth rate-dependent fashion and regulates its stability.

IFN-gamma/lipopolysaccharide activation of macrophages is associated with protein kinase C-dependent down-modulation of the colony-stimulating factor-1 receptor

In vitro natural cell-mediated cytotoxicity against Candida albicans: macrophage precursors as effector cells

Involvement of the protein tyrosine phosphatase SHP-1 in Ras-mediated activation of the mitogen-activated protein kinase pathway.

Keratinocyte-specific stat3 heterozygosity impairs development of skin tumors in human papillomavirus 8 transgenic mice.

Killing of yeast, germ-tube and mycelial forms of Candida albicans by murine effectors as measured by a radiolabel release microassay

Knock-in(g) RAF for a loop

Lipopolysaccharide induces activation of the Raf-1/MAP kinase pathway. A putative role for Raf-1 in the induction of the IL-1 beta and the TNF-alpha genes

Lipopolysaccharide induces jun N-terminal kinase activation in macrophages by a novel Cdc42/Rac-independent pathway involving sequential activation of protein kinase C zeta and phosphatidylcholine-dependent phospholipase C.

Listeria monocytogenes infection rewires host metabolism with regulatory input from type I interferons

Liver-associated macrophage precursor cells proliferate under impairment of regular hemopoiesis

Liver-associated macrophage precursors as natural cytotoxic effectors againstCandida albicans and Yac-1 cells

MEK1 is required for PTEN membrane recruitment, AKT regulation, and the maintenance of peripheral tolerance

MEK1 is required for the development of NRAS-driven leukemia

Macrophage function in murine allogeneic bone marrow radiation chimeras in the early phase after transplantation.

Modulation of polymorphonucleate-mediated cytotoxicity against Candida albicans by thymosin alpha 1.

Natural cell-mediated cytotoxicity against Candida albicans induced by cyclophosphamide: nature of the in vitro cytotoxic effector.

Opposite effects of different doses of MCSF on ERK phosphorylation and cell proliferation in macrophages

Organ-associated macrophage precursor activity: isolation of candidacidal and tumoricidal effectors from the spleens of cyclophosphamide-treated mice

Pancreatic β-cell Raf-1 is required for glucose tolerance, insulin secretion, and insulin 2 transcription

Partner exchange: protein-protein interactions in the Raf pathway

Phagocytic killing of Candida albicans by different murine effector cells

Protective role of Raf-1 in Salmonella-induced macrophage apoptosis

RAF dimers control vascular permeability and cytoskeletal rearrangements at endothelial cell-cell junctions

RAF proteins exert both specific and compensatory functions during tumour progression of NRAS-driven melanoma.

RAF1/BRAF dimerization integrates the signal from RAS to ERK and ROKα.