Lista de obras - Jane Skok - Dominio Público Uruguay

4C-ker: A Method to Reproducibly Identify Genome-Wide Interactions Captured by 4C-Seq Experiments

artículo científico publicado en 2016

A Damage-Independent Role for 53BP1 that Impacts Break Order and Igh Architecture during Class Switch Recombination

artículo científico publicado en 2016

A multifunctional element in the mouse Igκ locus that specifies repertoire and Ig loci subnuclear location.

artículo científico publicado en 2011

A new take on v(d)j recombination: transcription driven nuclear and chromatin reorganization in rag-mediated cleavage.

artículo científico

Active and Inactive Enhancers Cooperate to Exert Localized and Long-Range Control of Gene Regulation.

artículo científico publicado en 2016

Analysis of 3D genomic interactions identifies candidate host genes that transposable elements potentially regulate

article

Association between the Igk and Igh immunoglobulin loci mediated by the 3' Igk enhancer induces 'decontraction' of the Igh locus in pre-B cells

artículo científico publicado en 2008

B-1a cells acquire their unique characteristics by bypassing the pre-BCR selection stage

artículo científico publicado en 2019

Breaking TADs: insights into hierarchical genome organization.

artículo científico

C-terminal SRC kinase controls acute inflammation and granulocyte adhesion

artículo científico publicado en 2004

CRISPR-dCas9 and sgRNA scaffolds enable dual-colour live imaging of satellite sequences and repeat-enriched individual loci.

artículo científico publicado en 2016

CTCF and CTCFL in cancer

scientific article published on 22 April 2020

CTCF establishes discrete functional chromatin domains at the Hox clusters during differentiation

artículo científico publicado en 2015

Capturing the Onset of PRC2-Mediated Repressive Domain Formation

scientific article published on 01 June 2018

Close proximity to Igh is a contributing factor to AID-mediated translocations.

artículo científico publicado en 2012

Cohesin loss alters adult hematopoietic stem cell homeostasis, leading to myeloproliferative neoplasms

artículo científico publicado en 2015

Control of B-1a cell development by instructive BCR signaling

artículo científico publicado en 2018

DNA methylation disruption reshapes the hematopoietic differentiation landscape

artículo científico publicado en 2020

Defining the relative and combined contribution of CTCF and CTCFL to genomic regulation

scientific article published on 11 May 2020

Dendritic cell-derived IL-12 promotes B cell induction of Th2 differentiation: a feedback regulation of Th1 development

article

Dynamic changes in accessibility, nuclear positioning, recombination, and transcription at the Ig kappa locus.

artículo científico publicado en 2007

Enhancer talk

artículo científico publicado en 2018

EpiMethylTag: simultaneous detection of ATAC-seq or ChIP-seq signals with DNA methylation

scientific article published on 21 November 2019

Epigenetic ontogeny of the Igk locus during B cell development

artículo científico publicado en 2004

Equal opportunity for all.

artículo científico publicado en 2012

Erratum: Corrigendum: RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci

scholarly article published in Nature Immunology

Erratum: Corrigendum: RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci

scholarly article published in Nature Immunology

IL-7 functionally segregates the pro-B cell stage by regulating transcription of recombination mediators across cell cycle

artículo científico publicado en 2012

Identification of multi-loci hubs from 4C-seq demonstrates the functional importance of simultaneous interactions.

artículo científico publicado en 2016

Impaired Expression of Rearranged Immunoglobulin Genes and Premature p53 Activation Block B Cell Development in BMI1 Null Mice

artículo científico publicado en 2019

Interpreting 4C-Seq data: how far can we go?

artículo científico publicado en 2014

It takes two: communication between homologous alleles preserves genomic stability during V(D)J recombination.

artículo científico publicado en 2010

Jane Skok: choreography of allelic exclusion. [Interview by Hema Bashyam].

artículo científico publicado en 2008

Locus 'decontraction' and centromeric recruitment contribute to allelic exclusion of the immunoglobulin heavy-chain gene

artículo científico

Long-Range Regulation of V(D)J Recombination

artículo científico publicado en 2015

Low-Grade Astrocytoma Mutations in IDH1, P53, and ATRX Cooperate to Block Differentiation of Human Neural Stem Cells via Repression of SOX2.

artículo científico publicado en 2017

MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis

scientific article published on 24 August 2016

Mediator facilitates transcriptional activation and dynamic long-range contacts at the IgH locus during class switch recombination

artículo científico publicado en 2016

Molecular biology. Finding the right partner in a 3D genome.

artículo científico

NSD2 overexpression drives clustered chromatin and transcriptional changes in a subset of insulated domains

artículo científico publicado en 2019

Nonequivalent nuclear location of immunoglobulin alleles in B lymphocytes.

artículo científico publicado en 2001

Ontogeny and Vulnerabilities of Drug-Tolerant Persisters in HER2+ Breast Cancer

artículo científico publicado en 2021

Pax5 induces V-to-DJ rearrangements and locus contraction of the immunoglobulin heavy-chain gene

artículo científico publicado en 2004

RAG Off-Target Activity Is in the Loop

artículo científico publicado en 2015

RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci

scientific journal article

RNA Interactions Are Essential for CTCF-Mediated Genome Organization

scientific article published on 12 September 2019

Regulation of immunoglobulin light-chain recombination by the transcription factor IRF-4 and the attenuation of interleukin-7 signaling.

artículo científico publicado en 2008

Response to Casellas et al

artículo científico publicado en 2013

Reversible contraction by looping of the Tcra and Tcrb loci in rearranging thymocytes

artículo científico publicado en 2007

Rewiring of CD40 is necessary for delivery of rescue signals to B cells in germinal centres and subsequent entry into the memory pool.

artículo científico publicado en 2001

Scaffold association factor B (SAFB) is required for expression of prenyltransferases and RAS membrane association

artículo científico publicado en 2020

Silencing and nuclear repositioning of the lambda5 gene locus at the pre-B cell stage requires Aiolos and OBF-1.

artículo científico publicado en 2008

Stage-specific epigenetic regulation of CD4 expression by coordinated enhancer elements during T cell development

artículo científico publicado en 2018

Taking a break from the lab: can it really be done?

artículo científico publicado en 2014

The Conserved ATM Kinase RAG2-S365 Phosphorylation Site Limits Cleavage Events in Individual Cells Independent of Any Repair Defect

artículo científico publicado en 2017

The Ig heavy chain protein but not its message controls early B cell development

scientific article published on 23 November 2020

The IgH locus 3' cis-regulatory super-enhancer co-opts AID for allelic transvection

artículo científico publicado en 2017

The RAG2 C terminus suppresses genomic instability and lymphomagenesis ⬇️

artículo científico publicado el 3 de marzo de 2011

The novel lncRNA BlackMamba controls the neoplastic phenotype of ALK- anaplastic large cell lymphoma by regulating the DNA helicase HELLS

artículo científico publicado en 2020

The origin of recurrent translocations in recombining lymphocytes: a balance between break frequency and nuclear proximity.

artículo científico publicado en 2013

The pre-B-cell receptor induces silencing of VpreB and lambda5 transcription.

artículo científico publicado en 2005

The role of CTCF in regulating V(D)J recombination

artículo científico publicado en 2012

V(D)J recombination: a paradigm for studying chromosome interactions in mammalian cells

artículo científico publicado en 2010

VH replacement in primary immunoglobulin repertoire diversification.

artículo científico publicado en 2015

Wolf-Hirschhorn Syndrome Candidate 1 Is Necessary for Correct Hematopoietic and B Cell Development

artículo científico publicado en 2017

Yin Yang 1 is a critical regulator of B-cell development

artículo científico publicado en 2007

miRNAs Are Essential for the Regulation of the PI3K/AKT/FOXO Pathway and Receptor Editing during B Cell Maturation

artículo científico publicado en 2016

β-Catenin induces T-cell transformation by promoting genomic instability

artículo científico publicado en 2013

Lista de obras de Jane Skok

4C-ker: A Method to Reproducibly Identify Genome-Wide Interactions Captured by 4C-Seq Experiments

A Damage-Independent Role for 53BP1 that Impacts Break Order and Igh Architecture during Class Switch Recombination

A multifunctional element in the mouse Igκ locus that specifies repertoire and Ig loci subnuclear location.

A new take on v(d)j recombination: transcription driven nuclear and chromatin reorganization in rag-mediated cleavage.

Active and Inactive Enhancers Cooperate to Exert Localized and Long-Range Control of Gene Regulation.

Analysis of 3D genomic interactions identifies candidate host genes that transposable elements potentially regulate

Association between the Igk and Igh immunoglobulin loci mediated by the 3' Igk enhancer induces 'decontraction' of the Igh locus in pre-B cells

B-1a cells acquire their unique characteristics by bypassing the pre-BCR selection stage

Breaking TADs: insights into hierarchical genome organization.

C-terminal SRC kinase controls acute inflammation and granulocyte adhesion

CRISPR-dCas9 and sgRNA scaffolds enable dual-colour live imaging of satellite sequences and repeat-enriched individual loci.

CTCF and CTCFL in cancer

CTCF establishes discrete functional chromatin domains at the Hox clusters during differentiation

Capturing the Onset of PRC2-Mediated Repressive Domain Formation

Close proximity to Igh is a contributing factor to AID-mediated translocations.

Cohesin loss alters adult hematopoietic stem cell homeostasis, leading to myeloproliferative neoplasms

Control of B-1a cell development by instructive BCR signaling

DNA methylation disruption reshapes the hematopoietic differentiation landscape

Defining the relative and combined contribution of CTCF and CTCFL to genomic regulation

Dendritic cell-derived IL-12 promotes B cell induction of Th2 differentiation: a feedback regulation of Th1 development

Dynamic changes in accessibility, nuclear positioning, recombination, and transcription at the Ig kappa locus.

Enhancer talk

EpiMethylTag: simultaneous detection of ATAC-seq or ChIP-seq signals with DNA methylation

Epigenetic ontogeny of the Igk locus during B cell development

Equal opportunity for all.

Erratum: Corrigendum: RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci

Erratum: Corrigendum: RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci

IL-7 functionally segregates the pro-B cell stage by regulating transcription of recombination mediators across cell cycle

Identification of multi-loci hubs from 4C-seq demonstrates the functional importance of simultaneous interactions.

Impaired Expression of Rearranged Immunoglobulin Genes and Premature p53 Activation Block B Cell Development in BMI1 Null Mice

Interpreting 4C-Seq data: how far can we go?

It takes two: communication between homologous alleles preserves genomic stability during V(D)J recombination.

Jane Skok: choreography of allelic exclusion. [Interview by Hema Bashyam].

Locus 'decontraction' and centromeric recruitment contribute to allelic exclusion of the immunoglobulin heavy-chain gene

Long-Range Regulation of V(D)J Recombination

Low-Grade Astrocytoma Mutations in IDH1, P53, and ATRX Cooperate to Block Differentiation of Human Neural Stem Cells via Repression of SOX2.

MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis

Mediator facilitates transcriptional activation and dynamic long-range contacts at the IgH locus during class switch recombination

Molecular biology. Finding the right partner in a 3D genome.

NSD2 overexpression drives clustered chromatin and transcriptional changes in a subset of insulated domains

Nonequivalent nuclear location of immunoglobulin alleles in B lymphocytes.

Ontogeny and Vulnerabilities of Drug-Tolerant Persisters in HER2+ Breast Cancer

Pax5 induces V-to-DJ rearrangements and locus contraction of the immunoglobulin heavy-chain gene

RAG Off-Target Activity Is in the Loop

RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci

RNA Interactions Are Essential for CTCF-Mediated Genome Organization

Regulation of immunoglobulin light-chain recombination by the transcription factor IRF-4 and the attenuation of interleukin-7 signaling.

Response to Casellas et al

Reversible contraction by looping of the Tcra and Tcrb loci in rearranging thymocytes

Rewiring of CD40 is necessary for delivery of rescue signals to B cells in germinal centres and subsequent entry into the memory pool.

Scaffold association factor B (SAFB) is required for expression of prenyltransferases and RAS membrane association

Silencing and nuclear repositioning of the lambda5 gene locus at the pre-B cell stage requires Aiolos and OBF-1.

Stage-specific epigenetic regulation of CD4 expression by coordinated enhancer elements during T cell development

Taking a break from the lab: can it really be done?

The Conserved ATM Kinase RAG2-S365 Phosphorylation Site Limits Cleavage Events in Individual Cells Independent of Any Repair Defect

The Ig heavy chain protein but not its message controls early B cell development

The IgH locus 3' cis-regulatory super-enhancer co-opts AID for allelic transvection

The RAG2 C terminus suppresses genomic instability and lymphomagenesis ⬇️

The novel lncRNA BlackMamba controls the neoplastic phenotype of ALK- anaplastic large cell lymphoma by regulating the DNA helicase HELLS

The origin of recurrent translocations in recombining lymphocytes: a balance between break frequency and nuclear proximity.

The pre-B-cell receptor induces silencing of VpreB and lambda5 transcription.

The role of CTCF in regulating V(D)J recombination

V(D)J recombination: a paradigm for studying chromosome interactions in mammalian cells

VH replacement in primary immunoglobulin repertoire diversification.

Wolf-Hirschhorn Syndrome Candidate 1 Is Necessary for Correct Hematopoietic and B Cell Development

Yin Yang 1 is a critical regulator of B-cell development

miRNAs Are Essential for the Regulation of the PI3K/AKT/FOXO Pathway and Receptor Editing during B Cell Maturation

β-Catenin induces T-cell transformation by promoting genomic instability