Lista de obras - Frauke Melchior - Dominio Público Uruguay

"ChopNSpice," a mass spectrometric approach that allows identification of endogenous small ubiquitin-like modifier-conjugated peptides

artículo científico publicado en 2009

A fluorescence resonance energy transfer-based assay to study SUMO modification in solution

artículo científico publicado en 2005

A novel SUMO1-specific interacting motif in dipeptidyl peptidase 9 (DPP9) that is important for enzymatic regulation.

artículo científico publicado en 2012

A role for the Cajal-body-associated SUMO isopeptidase USPL1 in snRNA transcription mediated by RNA polymerase II.

artículo científico publicado en 2014

A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2

artículo científico publicado en 1997

A stable chemical SUMO1-Ubc9 conjugate specifically binds as a thioester mimic to the RanBP2-E3 ligase complex.

artículo científico publicado en 2015

Activation of transforming growth factor-beta signaling by SUMO-1 modification of tumor suppressor Smad4/DPC4

artículo científico publicado en 2003

An in vitro FRET-based assay for the analysis of SUMO conjugation and isopeptidase cleavage

artículo científico publicado en 2009

Bicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entry

artículo científico publicado en 2010

CRM1/Ran-mediated nuclear export of p27(Kip1) involves a nuclear export signal and links p27 export and proteolysis

artículo científico publicado en 2003

Calcium, viruses and nuclear pores: meeting report from the EMBO workshop 'Signal-Transduction-Mediated Regulation of Nuclear Transport', Strasbourg, France, 11--14 August 2001

scientific article published on 01 January 2002

Cell biology: SUMO.

artículo científico publicado en 2008

Concepts in sumoylation: a decade on

artículo científico publicado en 2007

Control of SUMO and Ubiquitin by ROS: Signaling and disease implications

scientific article published on 04 August 2018

Detecting endogenous SUMO targets in mammalian cells and tissues

artículo científico publicado en 2013

Dynamically regulated sumoylation of HDAC2 controls p53 deacetylation and restricts apoptosis following genotoxic stress

artículo científico publicado en 2012

Exploring the association between genetic variation in the SUMO isopeptidase gene USPL1 and breast cancer through integration of data from the population-based GENICA study and external genetic databases

artículo científico publicado en 2013

Frauke Melchior: How SUMO wrestles other proteins. Interview by Caitlin Sedwick.

artículo científico publicado en 2009

GTP hydrolysis by Ran occurs at the nuclear pore complex in an early step of protein import ⬇️

artículo científico publicado el 1 de noviembre de 1995

Grapevine stilbene synthase cDNA only slightly differing from chalcone synthase cDNA is expressed in Escherichia coli into a catalytically active enzyme

scientific article published on 01 July 1990

Hypoxia-induced Changes in SUMO Conjugation Affect Transcriptional Regulation Under Low Oxygen

scientific article published on 29 March 2019

IRAK2 directs stimulus-dependent nuclear export of inflammatory mRNAs.

artículo científico publicado en 2017

Identification and analysis of endogenous SUMO1 and SUMO2/3 targets in mammalian cells and tissues using monoclonal antibodies

artículo científico publicado en 2014

Importin α/β mediates nuclear import of individual SUMO E1 subunits and of the holo-enzyme

artículo científico publicado en 2011

In vivo localization and identification of SUMOylated proteins in the brain of His6-HA-SUMO1 knock-in mice

artículo científico publicado en 2012

Induction of stilbene synthase by Botrytis cinerea in cultured grapevine cells.

artículo científico publicado en 1991

Mdm2-SUMO1: is bigger better?

artículo científico publicado en 2000

Mechanism and consequences for paralog-specific sumoylation of ubiquitin-specific protease 25

artículo científico publicado en 2008

Modification of Ran GTPase-activating Protein by the Small Ubiquitin-related Modifier SUMO-1 Requires Ubc9, an E2-type Ubiquitin-conjugating Enzyme Homologue ⬇️

artículo científico publicado el 13 de marzo de 1998

Molecular Characterization of the SUMO-1 Modification of RanGAP1 and Its Role in Nuclear Envelope Association ⬇️

artículo científico publicado el 26 de enero de 1998

Nuclear Pore Complex Structure and Dynamics Revealed by Cryoelectron Tomography

scientific article published in Science

Nucleocytoplasmic transport: more than the usual suspects

artículo científico publicado en 2002

Opposed regulation of corepressor CtBP by SUMOylation and PDZ binding.

artículo científico publicado en 2003

PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies

artículo científico publicado en 2001

Performing in vitro sumoylation reactions using recombinant enzymes.

artículo científico publicado en 2009

Plant polyketide synthases leading to stilbenoids have a domain catalyzing malonyl-CoA:CO2 exchange, malonyl-CoA decarboxylation, and covalent enzyme modification and a site for chain lengthening

artículo científico publicado en 1997

Pyrophosphate modulates plant stress responses via SUMOylation

article

Quantitative SUMO-1 modification of a vaccinia virus protein is required for its specific localization and prevents its self-association

artículo científico publicado en 2005

RanGAP1*SUMO1 is phosphorylated at the onset of mitosis and remains associated with RanBP2 upon NPC disassembly

artículo científico publicado en 2004

RanGTP Targets p97 to RanBP2, a Filamentous Protein Localized at the Cytoplasmic Periphery of the Nuclear Pore Complex ⬇️

artículo científico publicado el 1 de diciembre de 1997

Recombinant reconstitution of sumoylation reactions in vitro

artículo científico publicado en 2012

Reconstitution of the Recombinant RanBP2 SUMO E3 Ligase Complex.

artículo científico publicado en 2016

Redox regulation of SUMO enzymes is required for ATM activity and survival in oxidative stress

artículo científico publicado en 2016

Regulation of SUMOylation by reversible oxidation of SUMO conjugating enzymes.

artículo científico publicado en 2006

Regulation of Smad4 sumoylation and transforming growth factor-beta signaling by protein inhibitor of activated STAT1.

artículo científico publicado en 2004

Retraction: Pyrophosphate modulates plant stress responses via SUMOylation

article

SCF<sup>Fbxw5</sup> targets kinesin-13 proteins to facilitate ciliogenesis

artículo científico publicado en 2021

SCFFbxw5 mediates transient degradation of actin remodeller Eps8 to allow proper mitotic progression

artículo científico publicado en 2013

SUMO modification of the ubiquitin-conjugating enzyme E2-25K

SUMO unloads the Kap114 cab.

artículo científico publicado en 2012

SUMO-1 and p53.

artículo científico publicado en 2002

SUMO: ligases, isopeptidases and nuclear pores

artículo científico publicado en 2003

SUMO: regulating the regulator.

artículo científico publicado en 2006

SUMOylation of the corepressor N-CoR modulates its capacity to repress transcription.

artículo científico publicado en 2006

SUMOylation-dependent LRH-1/PROX1 interaction promotes atherosclerosis by decreasing hepatic reverse cholesterol transport

artículo científico publicado en 2014

Sumoylation inhibits alpha-synuclein aggregation and toxicity.

artículo científico publicado en 2011

Sumoylation of the GTPase Ran by the RanBP2 SUMO E3 Ligase Complex.

artículo científico publicado en 2015

Sumoylation: a regulatory protein modification in health and disease

artículo científico publicado en 2013

The Nup358-RanGAP complex is required for efficient importin alpha/beta-dependent nuclear import

artículo científico publicado en 2008

The Ran GTPase-activating protein (RanGAP1) is critically involved in smooth muscle cell differentiation, proliferation and migration following vascular injury: implications for neointima formation and restenosis

artículo científico publicado en 2014

The RanBP2 SUMO E3 ligase is neither HECT- nor RING-type

scientific journal article

The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexes

artículo científico publicado en 2016

The RanBP2/RanGAP1*SUMO1/Ubc9 complex is a multisubunit SUMO E3 ligase.

artículo científico publicado en 2012

The SUMO E3 ligase RanBP2 promotes modification of the HDAC4 deacetylase

artículo científico publicado en 2002

The cytoplasmic peptidase DPP9 is rate-limiting for degradation of proline-containing peptides.

artículo científico publicado en 2009

The nucleoporin RanBP2 has SUMO1 E3 ligase activity

scientific journal article

The ubiquitin-like modifier FAT10 interferes with SUMO activation

scientific article published on 01 October 2019

Thiolutin is a zinc chelator that inhibits the Rpn11 and other JAMM metalloproteases

artículo científico publicado en 2017

Transcription factor Sp3 is silenced through SUMO modification by PIAS1

artículo científico publicado en 2002

Transient deSUMOylation of IRF2BP proteins controls early transcription in EGFR signaling

artículo científico publicado en 2021

Ubiquitin-related modifier SUMO1 and nucleocytoplasmic transport.

artículo científico publicado en 2002

Ubiquitin-specific protease-like 1 (USPL1) is a SUMO isopeptidase with essential, non-catalytic functions

artículo científico publicado en 2012

Lista de obras de Frauke Melchior

"ChopNSpice," a mass spectrometric approach that allows identification of endogenous small ubiquitin-like modifier-conjugated peptides

A fluorescence resonance energy transfer-based assay to study SUMO modification in solution

A novel SUMO1-specific interacting motif in dipeptidyl peptidase 9 (DPP9) that is important for enzymatic regulation.

A role for the Cajal-body-associated SUMO isopeptidase USPL1 in snRNA transcription mediated by RNA polymerase II.

A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2

A stable chemical SUMO1-Ubc9 conjugate specifically binds as a thioester mimic to the RanBP2-E3 ligase complex.

Activation of transforming growth factor-beta signaling by SUMO-1 modification of tumor suppressor Smad4/DPC4

An in vitro FRET-based assay for the analysis of SUMO conjugation and isopeptidase cleavage

Bicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entry

CRM1/Ran-mediated nuclear export of p27(Kip1) involves a nuclear export signal and links p27 export and proteolysis

Calcium, viruses and nuclear pores: meeting report from the EMBO workshop 'Signal-Transduction-Mediated Regulation of Nuclear Transport', Strasbourg, France, 11--14 August 2001

Cell biology: SUMO.

Concepts in sumoylation: a decade on

Control of SUMO and Ubiquitin by ROS: Signaling and disease implications

Detecting endogenous SUMO targets in mammalian cells and tissues

Dynamically regulated sumoylation of HDAC2 controls p53 deacetylation and restricts apoptosis following genotoxic stress

Exploring the association between genetic variation in the SUMO isopeptidase gene USPL1 and breast cancer through integration of data from the population-based GENICA study and external genetic databases

Frauke Melchior: How SUMO wrestles other proteins. Interview by Caitlin Sedwick.

GTP hydrolysis by Ran occurs at the nuclear pore complex in an early step of protein import ⬇️

Grapevine stilbene synthase cDNA only slightly differing from chalcone synthase cDNA is expressed in Escherichia coli into a catalytically active enzyme

Hypoxia-induced Changes in SUMO Conjugation Affect Transcriptional Regulation Under Low Oxygen

IRAK2 directs stimulus-dependent nuclear export of inflammatory mRNAs.

Identification and analysis of endogenous SUMO1 and SUMO2/3 targets in mammalian cells and tissues using monoclonal antibodies

Importin α/β mediates nuclear import of individual SUMO E1 subunits and of the holo-enzyme

In vivo localization and identification of SUMOylated proteins in the brain of His6-HA-SUMO1 knock-in mice

Induction of stilbene synthase by Botrytis cinerea in cultured grapevine cells.

Mdm2-SUMO1: is bigger better?

Mechanism and consequences for paralog-specific sumoylation of ubiquitin-specific protease 25

Modification of Ran GTPase-activating Protein by the Small Ubiquitin-related Modifier SUMO-1 Requires Ubc9, an E2-type Ubiquitin-conjugating Enzyme Homologue ⬇️

Molecular Characterization of the SUMO-1 Modification of RanGAP1 and Its Role in Nuclear Envelope Association ⬇️

Nuclear Pore Complex Structure and Dynamics Revealed by Cryoelectron Tomography

Nucleocytoplasmic transport: more than the usual suspects

Opposed regulation of corepressor CtBP by SUMOylation and PDZ binding.

PIASy, a nuclear matrix-associated SUMO E3 ligase, represses LEF1 activity by sequestration into nuclear bodies

Performing in vitro sumoylation reactions using recombinant enzymes.

Plant polyketide synthases leading to stilbenoids have a domain catalyzing malonyl-CoA:CO2 exchange, malonyl-CoA decarboxylation, and covalent enzyme modification and a site for chain lengthening

Pyrophosphate modulates plant stress responses via SUMOylation

Quantitative SUMO-1 modification of a vaccinia virus protein is required for its specific localization and prevents its self-association

RanGAP1*SUMO1 is phosphorylated at the onset of mitosis and remains associated with RanBP2 upon NPC disassembly

RanGTP Targets p97 to RanBP2, a Filamentous Protein Localized at the Cytoplasmic Periphery of the Nuclear Pore Complex ⬇️

Recombinant reconstitution of sumoylation reactions in vitro

Reconstitution of the Recombinant RanBP2 SUMO E3 Ligase Complex.

Redox regulation of SUMO enzymes is required for ATM activity and survival in oxidative stress

Regulation of SUMOylation by reversible oxidation of SUMO conjugating enzymes.

Regulation of Smad4 sumoylation and transforming growth factor-beta signaling by protein inhibitor of activated STAT1.

Retraction: Pyrophosphate modulates plant stress responses via SUMOylation

SCF<sup>Fbxw5</sup> targets kinesin-13 proteins to facilitate ciliogenesis

SCFFbxw5 mediates transient degradation of actin remodeller Eps8 to allow proper mitotic progression

SUMO modification of the ubiquitin-conjugating enzyme E2-25K

SUMO unloads the Kap114 cab.

SUMO-1 and p53.

SUMO: ligases, isopeptidases and nuclear pores

SUMO: regulating the regulator.

SUMOylation of the corepressor N-CoR modulates its capacity to repress transcription.

SUMOylation-dependent LRH-1/PROX1 interaction promotes atherosclerosis by decreasing hepatic reverse cholesterol transport

Sumoylation inhibits alpha-synuclein aggregation and toxicity.

Sumoylation of the GTPase Ran by the RanBP2 SUMO E3 Ligase Complex.

Sumoylation: a regulatory protein modification in health and disease

The Nup358-RanGAP complex is required for efficient importin alpha/beta-dependent nuclear import

The Ran GTPase-activating protein (RanGAP1) is critically involved in smooth muscle cell differentiation, proliferation and migration following vascular injury: implications for neointima formation and restenosis

The RanBP2 SUMO E3 ligase is neither HECT- nor RING-type

The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexes

The RanBP2/RanGAP1*SUMO1/Ubc9 complex is a multisubunit SUMO E3 ligase.

The SUMO E3 ligase RanBP2 promotes modification of the HDAC4 deacetylase

The cytoplasmic peptidase DPP9 is rate-limiting for degradation of proline-containing peptides.

The nucleoporin RanBP2 has SUMO1 E3 ligase activity

The ubiquitin-like modifier FAT10 interferes with SUMO activation

Thiolutin is a zinc chelator that inhibits the Rpn11 and other JAMM metalloproteases

Transcription factor Sp3 is silenced through SUMO modification by PIAS1

Transient deSUMOylation of IRF2BP proteins controls early transcription in EGFR signaling

Ubiquitin-related modifier SUMO1 and nucleocytoplasmic transport.

Ubiquitin-specific protease-like 1 (USPL1) is a SUMO isopeptidase with essential, non-catalytic functions