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Lista de obras de Ellen Fritsche

A Brainer on Neurotoxicity

artículo científico publicado en 2020

A Historical Perspective on the Use of Stem/Progenitor Cell-Based In Vitro Methods for Neurodevelopmental Toxicity Testing

article

A prevalent POLG CAG microsatellite length allele in humans and African great apes.

artículo científico publicado en 2004

A transcriptome comparison of time-matched developing human, mouse and rat neural progenitor cells reveals human uniqueness

artículo científico publicado en 2018

Activation of the aryl hydrocarbon receptor by the widely used Src family kinase inhibitor 4-amino-5-(4-chlorophenyl)-7-(dimethylethyl)pyrazolo[3,4-d]pyrimidine (PP2).

artículo científico publicado en 2014

Advancing human health risk assessment

artículo científico publicado en 2019

Advancing the science of developmental neurotoxicity (DNT): testing for better safety evaluation

artículo científico publicado en 2012

Allelic variants of drug metabolizing enzymes as risk factors in psoriasis

artículo científico publicado en 2003

Analysis of the transcriptional regulation and molecular function of the aryl hydrocarbon receptor repressor in human cell lines

artículo científico publicado en 2007

Application of the adverse outcome pathway concept for investigating developmental neurotoxicity potential of Chinese herbal medicines by using human neural progenitor cells in vitro

artículo científico publicado en 2022

Arsenite interrupts neurodevelopmental processes of human and rat neural progenitor cells: The role of reactive oxygen species and species-specific antioxidative defense

scientific article published on 17 June 2019

Aryl hydrocarbon receptor repressor (AhRR) function revisited: repression of CYP1 activity in human skin fibroblasts is not related to AhRR expression

artículo científico publicado en 2012

Automatic counting and positioning of 5-bromo-2-deoxyuridine (BrdU) positive cells in cortical layers of rat brain slices

artículo científico publicado en 2014

BDE-47 and 6-OH-BDE-47 modulate calcium homeostasis in primary fetal human neural progenitor cells via ryanodine receptor-independent mechanisms

artículo científico publicado en 2014

BDE-99 impairs differentiation of human and mouse NPCs into the oligodendroglial lineage by species-specific modes of action

scientific article published on 20 March 2017

Binding of epigallocatechin gallate to the laminin–β-integrin binding site decreases neural progenitor cell adhesion and migration: Adverse outcome pathway framework supporting neurodevelopmental toxicity research and risk assessment

artículo científico publicado en 2015

Building a developmental toxicity ontology

artículo científico publicado en 2018

Characterization and application of electrically active neuronal networks established from human induced pluripotent stem cell-derived neural progenitor cells for neurotoxicity evaluation

artículo científico publicado en 2020

Characterization of Skin Aging-Associated Secreted Proteins (SAASP) Produced by Dermal Fibroblasts Isolated from Intrinsically Aged Human Skin.

artículo científico publicado en 2015

Comparative human and rat "neurosphere assay" for developmental neurotoxicity testing.

artículo científico publicado en 2014

Comparative human and rat neurospheres reveal species differences in chemical effects on neurodevelopmental key events

artículo científico publicado en 2015

Comparative performance analysis of human iPSC-derived and primary neural progenitor cells (NPC) grown as neurospheres in vitro

artículo científico publicado en 2017

Comparison of migration disturbance potency of epigallocatechin gallate (EGCG) synthetic analogs and EGCG PEGylated PLGA nanoparticles in rat neurospheres

artículo científico publicado en 2018

Concepts in molecular dermatotoxicology

artículo científico publicado en 2006

Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes

artículo científico publicado en 2018

Corrigendum to "Current Availability of Stem Cell-Based In Vitro Methods for Developmental Neurotoxicity (DNT) Testing"

scientific article published on 01 October 2018

Corrigendum to Recommendation on test readiness criteria for new approach methods in toxicology: exemplified for developmental neurotoxicity

scientific article published on 01 January 2019

Culture of human neurospheres in 3D scaffolds for developmental neurotoxicity testing

artículo científico publicado en 2018

Current Availability of Stem Cell-Based In Vitro Methods for Developmental Neurotoxicity (DNT) Testing

scientific article published on 01 September 2018

Deficiency of the clock gene Bmal1 affects neural progenitor cell migration

artículo científico publicado en 2018

Developing and applying the adverse outcome pathway concept for understanding and predicting neurotoxicity

artículo científico publicado en 2016

Development of the Concept for Stem Cell-Based Developmental Neurotoxicity Evaluation

artículo científico publicado en 2018

Developmental neurotoxicity of MDMA. A systematic literature review summarized in a putative adverse outcome pathway

scientific article published on 05 December 2019

Differential cellular metabolite alterations in HaCaT cells caused by exposure to the aryl hydrocarbon receptor-binding polycyclic aromatic hydrocarbons chrysene, benzo[a]pyrene and dibenzo[a,l]pyrene

artículo científico publicado en 2016

ERK-dependent and -independent pathways trigger human neural progenitor cell migration

artículo científico publicado en 2007

Editorial: Developmental neurotoxicity

scientific article published on 17 July 2018

Effects of the genotoxic compounds, benzo[a]pyrene and cyclophosphamide on phase 1 and 2 activities in EpiDerm™ models

scientific article published on 17 December 2011

Efficient Modulation of TP53 Expression in Human Induced Pluripotent Stem Cells

artículo científico publicado en 2020

Elucidation of xenobiotic metabolism pathways in human skin and human skin models by proteomic profiling

artículo científico publicado en 2012

Epigallocatechin gallate (EGCG) inhibits adhesion and migration of neural progenitor cells in vitro

artículo científico publicado en 2016

Epigallocatechin-3-gallate does not affect the activity of enzymes involved in metabolic activation and cellular excretion of benzo[a]pyrene in human colon carcinoma cells ⬇️

artículo científico publicado el 31 de marzo de 2011

Erratum to Template for the description of cell-based toxicological test methods to allow evaluation and regulatory use of the data

artículo científico publicado en 2020

Estradiol protects dermal hyaluronan/versican matrix during photoaging by release of epidermal growth factor from keratinocytes.

artículo científico publicado en 2012

Evaluation of in vitro embryotoxicity tests for Chinese herbal medicines

scientific article published on 20 June 2019

Fibroblast origin shapes tissue homeostasis, epidermal differentiation, and drug uptake

artículo científico publicado en 2019

Human neurospheres as three-dimensional cellular systems for developmental neurotoxicity testing

artículo científico publicado en 2009

Impact of the arylhydrocarbon receptor on eugenol- and isoeugenol-induced cell cycle arrest in human immortalized keratinocytes (HaCaT).

artículo científico publicado en 2006

In vitro neurotoxicity data in human risk assessment of polybrominated diphenyl ethers (PBDEs): overview and perspectives.

artículo científico publicado en 2011

Inadequate mito-biogenesis in primary dermal fibroblasts from old humans is associated with impairment of PGC1A-independent stimulation.

artículo científico publicado en 2014

International STakeholder NETwork (ISTNET) for creating a developmental neurotoxicity testing (DNT) roadmap for regulatory purposes

artículo científico publicado en 2014

International STakeholder NETwork (ISTNET): creating a developmental neurotoxicity (DNT) testing road map for regulatory purposes

artículo científico publicado en 2015

Investigation into experimental toxicological properties of plant protection products having a potential link to Parkinson's disease and childhood leukaemia†

artículo científico publicado en 2017

Is Intake of Flavonoid-Based Food Supplements During Pregnancy Safe for the Developing Child? A Literature Review

artículo científico

Lightening up the UV response by identification of the arylhydrocarbon receptor as a cytoplasmatic target for ultraviolet B radiation.

artículo científico publicado en 2007

Luteolin enhances the bioavailability of benzo(a)pyrene in human colon carcinoma cells

artículo científico publicado en 2010

Nanoparticles Dysregulate the Human Placental Secretome with Consequences on Angiogenesis and Vascularization

artículo científico publicado en 2024

Neural In Vitro Models for Studying Substances Acting on the Central Nervous System

artículo científico publicado en 2020

Neural progenitor cells as models for high-throughput screens of developmental neurotoxicity: state of the science.

artículo científico publicado en 2009

Neuronal Differentiation from Induced Pluripotent Stem Cell-Derived Neurospheres by the Application of Oxidized Alginate-Gelatin-Laminin Hydrogels

Neurospheres as a Model for Developmental Neurotoxicity Testing ⬇️

artículo científico publicado el 1 de enero de 2011

Nitric oxide stimulates human neural progenitor cell migration via cGMP-mediated signal transduction ⬇️

artículo científico publicado el 19 de octubre de 2010

Novel chemical hazard characterisation approaches

artículo científico publicado en 2016

OECD/EFSA workshop on developmental neurotoxicity (DNT): The use of non-animal test methods for regulatory purposes.

artículo científico publicado en 2017

Omnisphero: a high-content image analysis (HCA) approach for phenotypic developmental neurotoxicity (DNT) screenings of organoid neurosphere cultures in vitro.

artículo científico publicado en 2016

Ontogenetic expression of thyroid hormone signaling genes: An in vitro and in vivo species comparison

artículo científico publicado en 2019

Polybrominated diphenyl ethers induce developmental neurotoxicity in a human in vitro model: evidence for endocrine disruption

artículo científico publicado en 2010

Polychlorinated biphenyls disturb differentiation of normal human neural progenitor cells: clue for involvement of thyroid hormone receptors

artículo científico publicado en 2005

Proteome-wide analysis reveals an age-associated cellular phenotype of in situ aged human fibroblasts

artículo científico publicado en 2014

Putative adverse outcome pathways relevant to neurotoxicity

artículo científico publicado en 2015

Recommendation on test readiness criteria for new approach methods in toxicology: Exemplified for developmental neurotoxicity

artículo científico publicado en 2018

Reference compounds for alternative test methods to indicate developmental neurotoxicity (DNT) potential of chemicals: example lists and criteria for their selection and use.

artículo científico publicado en 2016

Regulation of dioxin receptor function by different beta-carboline alkaloids

artículo científico publicado en 2010

Role of the aryl hydrocarbon receptor in tobacco smoke extract-induced matrix metalloproteinase-1 expression.

artículo científico publicado en 2013

Species-specific differential AhR expression protects human neural progenitor cells against developmental neurotoxicity of PAHs

artículo científico publicado en 2010

State-of-the-art of 3D cultures (organs-on-a-chip) in safety testing and pathophysiology

artículo científico publicado en 2014

Stem Cells for Next Level Toxicity Testing in the 21st Century

artículo científico publicado en 2020

Template for the description of cell-based toxicological test methods to allow evaluation and regulatory use of the data

scientific article published on 01 January 2019

The AhR–Nrf2 Pathway in Keratinocytes: On the Road to Chemoprevention? ⬇️

artículo científico publicado el 1 de enero de 2012

The Aryl Hydrocarbon Receptor Is Involved in UVR-Induced Immunosuppression ⬇️

artículo científico publicado el 7 de mayo de 2013

The ENDpoiNTs Project: Novel Testing Strategies for Endocrine Disruptors Linked to Developmental Neurotoxicity

scientific article published on 01 June 2020

The European Long-range Research Initiative (LRI): A decade of contributions to human health protection, exposure modelling and environmental integrity

artículo científico

The aryl hydrocarbon receptor and light

artículo científico publicado en 2006

The hallmarks of fibroblast ageing

artículo científico

The new aryl hydrocarbon receptor antagonist E/Z-2-benzylindene-5,6-dimethoxy-3,3-dimethylindan-1-one protects against UVB-induced signal transduction.

artículo científico publicado en 2013

Tissue distribution and function of the Aryl hydrocarbon receptor repressor (AhRR) in C57BL/6 and Aryl hydrocarbon receptor deficient mice

artículo científico publicado en 2006

Update of the DevTox data database for harmonized risk assessment and alternative methodologies in developmental toxicology: Report of the 9th Berlin Workshop on Developmental Toxicity

scientific article published on 06 July 2019

Use of Human In Vitro Skin Models for Accurate and Ethical Risk Assessment: Metabolic Considerations ⬇️

artículo científico publicado el 28 de marzo de 2013

Xenobiotic metabolism capacities of human skin in comparison with a 3D epidermis model and keratinocyte-based cell culture as in vitro alternatives for chemical testing: activating enzymes (Phase I).

artículo científico publicado en 2012

Xenobiotic metabolism capacities of human skin in comparison with a 3D‐epidermis model and keratinocyte‐based cell culture as in vitro alternatives for chemical testing: phase II enzymes ⬇️

artículo científico publicado el 1 de mayo de 2012

miR-23a-3p causes cellular senescence by targeting hyaluronan synthase 2: possible implication for skin aging

artículo científico publicado en 2014

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