Lista de obras - Beate Koksch - Dominio Público Uruguay

A New Approach to Glycopeptides

artículo científico publicado en 1999

A Self-Assembling Peptide Scaffold for the Multivalent Presentation of Antigens

artículo científico publicado en 2015

A Sustainable, Semi-Continuous Flow Synthesis of Hydantoins

artículo científico publicado en 2016

A beta/gamma motif to mimic alpha-helical turns in proteins

artículo científico publicado en 2010

A helix-forming αβγ-chimeric peptide with catalytic activity: a hybrid peptide ligase ⬇️

artículo científico publicado el 15 de febrero de 2011

A molecular dynamics study of the formation, stability, and oligomerization state of two designed coiled coils: possibilities and limitations

artículo científico publicado en 2005

A systematic study of fundamentals in α-helical coiled coil mimicry by alternating sequences of β- and γ-amino acids.

artículo científico publicado en 2011

Advanced approaches for the characterization of a de novo designed antiparallel coiled coil peptide

artículo científico publicado en 2005

Amide-I and -II vibrations of the cyclic beta-sheet model peptide gramicidin S in the gas phase

artículo científico publicado en 2010

Amide-to-ester substitution in coiled coils: the effect of removing hydrogen bonds on protein structure.

artículo científico publicado en 2007

Amyloidogenic peptides at hydrophobic-hydrophilic interfaces: coordination affinities and the chelate effect dictate the competitive binding of Cu2+ and Zn2+.

artículo científico publicado en 2011

An Intrinsic Hydrophobicity Scale for Amino Acids and Its Application to Fluorinated Compounds

scientific article published on 10 May 2019

An unusual interstrand H-bond stabilizes the heteroassembly of helical αβγ-chimeras with natural peptides

artículo científico publicado en 2014

Approaches to Obtaining Fluorinated α-Amino Acids

scientific article published on 22 August 2019

Balancing selectivity vs stability using molecular dynamics and umbrella sampling

artículo científico publicado en 2014

Biocatalysis with Unnatural Amino Acids: Enzymology Meets Xenobiology

artículo científico publicado en 2017

Catalytic Activity of Peptide-Nanoparticle Conjugates Regulated by a Conformational Change

artículo científico publicado en 2017

Catalytically Active Peptide-Gold Nanoparticle Conjugates: Prospecting for Artificial Enzymes

scientific article published on 06 January 2020

Cationic membrane-active peptides - anticancer and antifungal activity as well as penetration into human skin

artículo científico publicado en 2014

Chemical aminoacylation of tRNAs with fluorinated amino acids for in vitro protein mutagenesis

artículo científico publicado en 2010

Chemical labeling strategy with (R)- and (S)-trifluoromethylalanine for solid state 19F NMR analysis of peptaibols in membranes

artículo científico publicado en 2009

Coassembly Generates Peptide Hydrogel with Wound Dressing Material Properties

scientific article published on 07 April 2020

Coiled-coils in phage display screening: insight into exceptional selectivity provided by molecular dynamics.

artículo científico publicado en 2015

Compatibility of the conformationally rigid CF3-Bpg side chain with the hydrophobic coiled-coil interface

artículo científico publicado en 2010

Concluding the amyloid formation pathway of a coiled-coil-based peptide from the size of the critical nucleus

artículo científico publicado en 2014

Conjugate hydrotrifluoromethylation of α,β-unsaturated acyl-oxazolidinones: synthesis of chiral fluorinated amino acids ⬇️

artículo científico publicado el 21 de noviembre de 2012

Deciphering the Fluorine Code-The Many Hats Fluorine Wears in a Protein Environment.

artículo científico publicado en 2017

Design and characterization of endosomal-pH-responsive coiled coils for constructing an artificial membrane fusion system

artículo científico publicado en 2011

Design, synthesis, inhibition studies, and molecular modeling of pepstatin analogues addressing different secreted aspartic proteinases of Candida albicans

artículo científico publicado en 2012

Development of zinc finger domains for recognition of the 5'-CNN-3' family DNA sequences and their use in the construction of artificial transcription factors

artículo científico publicado en 2005

Direct one-step 18F-labeling of peptides via nucleophilic aromatic substitution

artículo científico publicado en 2009

Directing the secondary structure of polypeptides at will: from helices to amyloids and back again?

artículo científico publicado en 2005

Discovery and Investigation of Natural Editing Function against Artificial Amino Acids in Protein Translation

artículo científico publicado en 2017

Editorial overview: Synthetic biomolecules: Biopolymers

artículo científico publicado en 2017

Effects of fluorination on the folding kinetics of a heterodimeric coiled coil

artículo científico publicado en 2009

Enzymatically triggered amyloid formation: an approach for studying peptide aggregation

artículo científico publicado en 2010

Evaluation of a modular strategy for the construction of novel polydactyl zinc finger DNA-binding proteins

artículo científico publicado en 2003

Evaluation of the molecular interactions of fluorinated amino acids with native polypeptides

artículo científico publicado en 2004

Exploiting Oligo(amido amine) Backbones for the Multivalent Presentation of Coiled-Coil Peptides

artículo científico publicado en 2015

Exploring the conformational preferences of 20-residue peptides in isolation: Ac-Ala19-Lys + H(+)vs. Ac-Lys-Ala19 + H(+) and the current reach of DFT.

artículo científico publicado en 2015

Fluorinated amino acids in amyloid formation: a symphony of size, hydrophobicity and α-helix propensity

article published in 2014

Fluorinated amino acids: compatibility with native protein structures and effects on protein-protein interactions.

artículo científico publicado en 2011

Fluorine in Peptide Design and Protein Engineering

article by Christian Jäckel & Beate Koksch published November 2005 in European Journal of Organic Chemistry

Fluorine in a native protein environment--How the spatial demand and polarity of fluoroalkyl groups affect protein folding

artículo científico publicado en 2006

Fluorine in protein environments: a QM and MD study

artículo científico publicado en 2009

Fluorine teams up with water to restore inhibitor activity to mutant BPTI.

artículo científico publicado en 2015

Fluoro-modified chemotactic peptides: fMLF analogues

artículo científico publicado en 2004

Following polypeptide folding and assembly with conformational switches

artículo científico publicado en 2008

Formation of α-helical nanofibers by mixing β-structured and α-helical coiled coil peptides

artículo científico publicado en 2012

From alpha-helix to beta-sheet--a reversible metal ion induced peptide secondary structure switch

artículo científico publicado en 2005

Global substitution of hemeproteins with noncanonical amino acids in Escherichia coli with intact cofactor maturation machinery

artículo científico publicado en 2017

Hexafluoroacetone as a Protecting and Activating Reagent: Synthesis of New Types of Fluoro-Substituted α-Amino, α-Hydroxy and α-Mercapto Acids

Highly dynamic motion of crown ethers along oligolysine peptide chains ⬇️

artículo científico publicado el 30 de agosto de 2009

How C(alpha)-Fluoroalkyl amino acids and peptides interact with enzymes: studies concerning the influence on proteolytic stability, enzymatic resolution and peptide coupling

artículo científico publicado en 2006

How cations change peptide structure.

artículo científico publicado en 2013

How metal ions affect amyloid formation: Cu2+- and Zn2+-sensitive peptides

artículo científico publicado en 2008

How post-translational modifications influence amyloid formation: a systematic study of phosphorylation and glycosylation in model peptides

artículo científico publicado en 2010

Impact of fluorination on proteolytic stability of peptides in human blood plasma

artículo científico publicado en 2013

Impact of fluorination on proteolytic stability of peptides: a case study with α-chymotrypsin and pepsin

artículo científico publicado en 2014

Impact of multivalent charge presentation on peptide-nanoparticle aggregation

artículo científico publicado en 2015

Inhibition of Amyloid Aggregation by Formation of Helical Assemblies ⬇️

artículo científico publicado el 12 de septiembre de 2011

Inhibition of peptide aggregation by means of enzymatic phosphorylation

artículo científico publicado en 2016

Intramolecular charge interactions as a tool to control the coiled-coil-to-amyloid transformation

artículo científico publicado en 2008

Investigation of the network of preferred interactions in an artificial coiled-coil association using the peptide array technique ⬇️

artículo científico publicado el 25 de abril de 2012

Investigation of the synthetic route to pepstatin analogues by SPPS using O-protected and O-unprotected statine as building blocks

artículo científico publicado en 2009

Laboratory evolution of Escherichia coli enables life based on fluorinated amino acids

scholarly article published 10 June 2019

Mechanism of discrimination of isoleucyl-tRNA synthetase against nonproteinogenic α-aminobutyrate and its fluorinated analogues

scientific article published on 18 September 2019

Membrane binding and structure of de novo designed alpha-helical cationic coiled-coil-forming peptides

artículo científico publicado en 2006

Membrane binding of peptide models for early stages of amyloid formation: Lipid packing counts more than charge

artículo científico publicado en 2016

Modifizierung von Peptiden

artículo científico publicado en 1998

Molecular Interactions of Fluorinated Amino Acids in a Native Polypeptide Environment

Multiomics Analysis Provides Insight into the Laboratory Evolution of Escherichia coli toward the Metabolic Usage of Fluorinated Indoles

artículo científico publicado en 2020

Multiple glycosylation of de novo designed alpha-helical coiled coil peptides

artículo científico publicado en 2010

Multivalency as a chemical organization and action principle

artículo científico publicado en 2012

NFGAIL Amyloid Oligomers: The Onset of Beta-Sheet Formation and the Mechanism for Fibril Formation

artículo científico publicado en 2017

Nanoparticle-induced folding and fibril formation of coiled-coil-based model peptides

artículo científico publicado en 2010

Nanoscale imaging reveals laterally expanding antimicrobial pores in lipid bilayers ⬇️

artículo científico publicado el 13 de mayo de 2013

Native like helices in a specially designed β peptide in the gas phase

artículo científico publicado en 2015

Orthogonal translation meets electron transfer: in vivo labeling of cytochrome c for probing local electric fields

artículo científico publicado en 2015

Peptide adsorption to cyanine dye aggregates revealed by cryo-transmission electron microscopy

artículo científico publicado en 2010

Position-dependent effects of fluorinated amino acids on the hydrophobic core formation of a heterodimeric coiled coil

artículo científico publicado en 2009

Position-dependent impact of hexafluoroleucine and trifluoroisoleucine on protease digestion

artículo científico publicado en 2017

Proline-glutamate chimera's side chain conformation directs the type of β-hairpin structure

artículo científico publicado en 2013

Protease-catalyzed peptide synthesis for the site-specific incorporation of alpha-fluoroalkyl amino acids into peptides

artículo científico publicado en 2003

Random coils, beta-sheet ribbons, and alpha-helical fibers: one peptide adopting three different secondary structures at will

artículo científico publicado en 2006

Selection of a buried salt bridge by phage display

artículo científico publicado en 2009

Self-Assembling Peptides as Extracellular Matrix Mimics to Influence Stem Cell's Fate

Simple machine-assisted protocol for solid-phase synthesis of depsipeptides

artículo científico publicado en 2007

Specific in situ discrimination of amyloid fibrilsversus α-helical fibres by the fluorophore NIAD-4 ⬇️

artículo científico publicado el 24 de noviembre de 2011

Structural determinants of coiled coil mechanics

scientific article published on 01 May 2019

Structure analysis of an amyloid-forming model peptide by a systematic glycine and proline scan

artículo científico publicado en 2011

Substrate specificity of an actively assembling amyloid catalyst

artículo científico publicado en 2016

Switchable electrostatic interactions between gold nanoparticles and coiled coil peptides direct colloid assembly

artículo científico publicado en 2008

Synthesis of enantiomerically pure (2S,3S)-5,5,5-trifluoroisoleucine and (2R,3S)-5,5,5-trifluoro-allo-isoleucine

artículo científico publicado en 2013

Synthetic strategies to alpha-trifluoromethyl and alpha-difluoromethyl substituted alpha-amino acids

artículo científico publicado en 2008

Tailored Presentation of Carbohydrates on a Coiled Coil-Based Scaffold for Asialoglycoprotein Receptor Targeting

artículo científico publicado en 2015

The Amyloid Precursor Protein C-Terminal Fragment C100 Occurs in Monomeric and Dimeric Stable Conformations and Binds γ-Secretase Modulators ⬇️

artículo científico publicado el 11 de enero de 2011

The Impact of Halogenated Phenylalanine Derivatives on NFGAIL Amyloid Formation

scientific article published on 23 September 2020

The protofilament architecture of a de novo designed coiled coil-based amyloidogenic peptide

Towards identifying preferred interaction partners of fluorinated amino acids within the hydrophobic environment of a dimeric coiled coil peptide

artículo científico publicado en 2010

Towards understanding secondary structure transitions: phosphorylation and metal coordination in model peptides

artículo científico publicado en 2010

Triggers for β-sheet formation at the hydrophobic-hydrophilic interface: high concentration, in-plane orientational order, and metal ion complexation

scientific article published on 07 November 2011

Using the Potential of Fluorine for Peptide and Protein Modification

β- and γ-Amino Acids at α-Helical Interfaces: Toward the Formation of Highly Stable Foldameric Coiled Coils

artículo científico publicado en 2014

Lista de obras de Beate Koksch

A New Approach to Glycopeptides

A Self-Assembling Peptide Scaffold for the Multivalent Presentation of Antigens

A Sustainable, Semi-Continuous Flow Synthesis of Hydantoins

A beta/gamma motif to mimic alpha-helical turns in proteins

A helix-forming αβγ-chimeric peptide with catalytic activity: a hybrid peptide ligase ⬇️

A molecular dynamics study of the formation, stability, and oligomerization state of two designed coiled coils: possibilities and limitations

A systematic study of fundamentals in α-helical coiled coil mimicry by alternating sequences of β- and γ-amino acids.

Advanced approaches for the characterization of a de novo designed antiparallel coiled coil peptide

Amide-I and -II vibrations of the cyclic beta-sheet model peptide gramicidin S in the gas phase

Amide-to-ester substitution in coiled coils: the effect of removing hydrogen bonds on protein structure.

Amyloidogenic peptides at hydrophobic-hydrophilic interfaces: coordination affinities and the chelate effect dictate the competitive binding of Cu2+ and Zn2+.

An Intrinsic Hydrophobicity Scale for Amino Acids and Its Application to Fluorinated Compounds

An unusual interstrand H-bond stabilizes the heteroassembly of helical αβγ-chimeras with natural peptides

Approaches to Obtaining Fluorinated α-Amino Acids

Balancing selectivity vs stability using molecular dynamics and umbrella sampling

Biocatalysis with Unnatural Amino Acids: Enzymology Meets Xenobiology

Catalytic Activity of Peptide-Nanoparticle Conjugates Regulated by a Conformational Change

Catalytically Active Peptide-Gold Nanoparticle Conjugates: Prospecting for Artificial Enzymes

Cationic membrane-active peptides - anticancer and antifungal activity as well as penetration into human skin

Chemical aminoacylation of tRNAs with fluorinated amino acids for in vitro protein mutagenesis

Chemical labeling strategy with (R)- and (S)-trifluoromethylalanine for solid state 19F NMR analysis of peptaibols in membranes

Coassembly Generates Peptide Hydrogel with Wound Dressing Material Properties

Coiled-coils in phage display screening: insight into exceptional selectivity provided by molecular dynamics.

Compatibility of the conformationally rigid CF3-Bpg side chain with the hydrophobic coiled-coil interface

Concluding the amyloid formation pathway of a coiled-coil-based peptide from the size of the critical nucleus

Conjugate hydrotrifluoromethylation of α,β-unsaturated acyl-oxazolidinones: synthesis of chiral fluorinated amino acids ⬇️

Deciphering the Fluorine Code-The Many Hats Fluorine Wears in a Protein Environment.

Design and characterization of endosomal-pH-responsive coiled coils for constructing an artificial membrane fusion system

Design, synthesis, inhibition studies, and molecular modeling of pepstatin analogues addressing different secreted aspartic proteinases of Candida albicans

Development of zinc finger domains for recognition of the 5'-CNN-3' family DNA sequences and their use in the construction of artificial transcription factors

Direct one-step 18F-labeling of peptides via nucleophilic aromatic substitution

Directing the secondary structure of polypeptides at will: from helices to amyloids and back again?

Discovery and Investigation of Natural Editing Function against Artificial Amino Acids in Protein Translation

Editorial overview: Synthetic biomolecules: Biopolymers

Effects of fluorination on the folding kinetics of a heterodimeric coiled coil

Enzymatically triggered amyloid formation: an approach for studying peptide aggregation

Evaluation of a modular strategy for the construction of novel polydactyl zinc finger DNA-binding proteins

Evaluation of the molecular interactions of fluorinated amino acids with native polypeptides

Exploiting Oligo(amido amine) Backbones for the Multivalent Presentation of Coiled-Coil Peptides

Exploring the conformational preferences of 20-residue peptides in isolation: Ac-Ala19-Lys + H(+)vs. Ac-Lys-Ala19 + H(+) and the current reach of DFT.

Fluorinated amino acids in amyloid formation: a symphony of size, hydrophobicity and α-helix propensity

Fluorinated amino acids: compatibility with native protein structures and effects on protein-protein interactions.

Fluorine in Peptide Design and Protein Engineering

Fluorine in a native protein environment--How the spatial demand and polarity of fluoroalkyl groups affect protein folding

Fluorine in protein environments: a QM and MD study

Fluorine teams up with water to restore inhibitor activity to mutant BPTI.

Fluoro-modified chemotactic peptides: fMLF analogues

Following polypeptide folding and assembly with conformational switches

Formation of α-helical nanofibers by mixing β-structured and α-helical coiled coil peptides

From alpha-helix to beta-sheet--a reversible metal ion induced peptide secondary structure switch

Global substitution of hemeproteins with noncanonical amino acids in Escherichia coli with intact cofactor maturation machinery

Hexafluoroacetone as a Protecting and Activating Reagent: Synthesis of New Types of Fluoro-Substituted α-Amino, α-Hydroxy and α-Mercapto Acids

Highly dynamic motion of crown ethers along oligolysine peptide chains ⬇️

How C(alpha)-Fluoroalkyl amino acids and peptides interact with enzymes: studies concerning the influence on proteolytic stability, enzymatic resolution and peptide coupling

How cations change peptide structure.

How metal ions affect amyloid formation: Cu2+- and Zn2+-sensitive peptides

How post-translational modifications influence amyloid formation: a systematic study of phosphorylation and glycosylation in model peptides

Impact of fluorination on proteolytic stability of peptides in human blood plasma

Impact of fluorination on proteolytic stability of peptides: a case study with α-chymotrypsin and pepsin

Impact of multivalent charge presentation on peptide-nanoparticle aggregation

Inhibition of Amyloid Aggregation by Formation of Helical Assemblies ⬇️

Inhibition of peptide aggregation by means of enzymatic phosphorylation

Intramolecular charge interactions as a tool to control the coiled-coil-to-amyloid transformation

Investigation of the network of preferred interactions in an artificial coiled-coil association using the peptide array technique ⬇️

Investigation of the synthetic route to pepstatin analogues by SPPS using O-protected and O-unprotected statine as building blocks

Laboratory evolution of Escherichia coli enables life based on fluorinated amino acids

Mechanism of discrimination of isoleucyl-tRNA synthetase against nonproteinogenic α-aminobutyrate and its fluorinated analogues

Membrane binding and structure of de novo designed alpha-helical cationic coiled-coil-forming peptides

Membrane binding of peptide models for early stages of amyloid formation: Lipid packing counts more than charge

Modifizierung von Peptiden

Molecular Interactions of Fluorinated Amino Acids in a Native Polypeptide Environment

Multiomics Analysis Provides Insight into the Laboratory Evolution of Escherichia coli toward the Metabolic Usage of Fluorinated Indoles

Multiple glycosylation of de novo designed alpha-helical coiled coil peptides

Multivalency as a chemical organization and action principle

NFGAIL Amyloid Oligomers: The Onset of Beta-Sheet Formation and the Mechanism for Fibril Formation

Nanoparticle-induced folding and fibril formation of coiled-coil-based model peptides

Nanoscale imaging reveals laterally expanding antimicrobial pores in lipid bilayers ⬇️

Native like helices in a specially designed β peptide in the gas phase

Orthogonal translation meets electron transfer: in vivo labeling of cytochrome c for probing local electric fields