Lista de obras - Almut Schulze - Dominio Público Uruguay

3D Growth of Cancer Cells Elicits Sensitivity to Kinase Inhibitors but Not Lipid Metabolism Modifiers

artículo científico publicado en 2019

6-Phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 is essential for p53-null cancer cells.

artículo científico publicado en 2017

A MYC-GCN2-eIF2α negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer

scientific article published on 04 November 2019

A computational study of the Warburg effect identifies metabolic targets inhibiting cancer migration

artículo científico publicado en 2014

A fresh look at cancer metabolism in a historical setting ⬇️

artículo científico publicado el 18 de marzo de 2011

A new player in the orchestra of cell growth: SREBP activity is regulated by mTORC1 and contributes to the regulation of cell and organ size

artículo científico publicado en 2009

Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress

artículo científico publicado en 2015

Activation of cyclin A gene expression by the cyclin encoded by human herpesvirus-8.

artículo científico publicado en 1999

Analysis of the transcriptional program induced by Raf in epithelial cells

artículo científico publicado en 2001

Anchorage-dependent transcription of the cyclin A gene

artículo científico publicado en 1996

Antagonism between FOXO and MYC Regulates Cellular Powerhouse

artículo científico

Cathepsin Inhibition Modulates Metabolism and Polarization of Tumor-Associated Macrophages

artículo científico publicado en 2020

Cell cycle regulation of the cyclin A gene promoter is mediated by a variant E2F site

artículo científico publicado en 1995

Cellular fatty acid metabolism and cancer

scientific article published on 20 June 2013

Cholesteryl esters: fueling the fury of prostate cancer.

artículo científico publicado en 2014

Direct control of caveolin-1 expression by FOXO transcription factors

artículo científico publicado en 2005

Erratum: Corrigendum: How cancer metabolism is tuned for proliferation and vulnerable to disruption

artículo científico publicado en 2013

FOXO3a regulates reactive oxygen metabolism by inhibiting mitochondrial gene expression

artículo científico publicado en 2011

Fatty acid uptake and lipid storage induced by HIF-1α contribute to cell growth and survival after hypoxia-reoxygenation

artículo científico publicado en 2014

Flicking the Warburg Switch—Tyrosine Phosphorylation of Pyruvate Dehydrogenase Kinase Regulates Mitochondrial Activity in Cancer Cells ⬇️

artículo científico publicado el 23 de diciembre de 2011

Flux balance analysis predicts essential genes in clear cell renal cell carcinoma metabolism

artículo científico publicado en 2015

Functional metabolic screen identifies 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 as an important regulator of prostate cancer cell survival.

artículo científico publicado en 2012

Functional screening identifies MCT4 as a key regulator of breast cancer cell metabolism and survival

artículo científico publicado en 2015

Genetic ablation of S6-kinase does not prevent processing of SREBP1

artículo científico publicado en 2010

Genome-wide analysis of FOXO3 mediated transcription regulation through RNA polymerase II profiling

artículo científico publicado en 2013

Glycolysis back in the limelight: systemic targeting of HK2 blocks tumor growth

artículo científico publicado en 2013

Hooked on fat: the role of lipid synthesis in cancer metabolism and tumour development

artículo científico publicado en 2013

How cancer metabolism is tuned for proliferation and vulnerable to disruption ⬇️

artículo científico publicado el 15 de noviembre de 2012

Induction of Mxi1-SR alpha by FOXO3a contributes to repression of Myc-dependent gene expression

artículo científico publicado en 2007

Involvement of MINK, a Ste20 family kinase, in Ras oncogene-induced growth arrest in human ovarian surface epithelial cells

artículo científico publicado en 2005

LXRα activation and Raf inhibition trigger lethal lipotoxicity in liver cancer

artículo científico publicado en 2021

Linking Glycogen and Senescence in Cancer Cells ⬇️

artículo científico publicado el 5 de diciembre de 2012

Lipid desaturation - the next step in targeting lipogenesis in cancer?

artículo científico publicado en 2016

Lipid metabolism in cancer

artículo científico

Metabotypes of breast cancer cell lines revealed by non-targeted metabolomics

artículo científico publicado en 2016

Mevalonate Pathway Provides Ubiquinone to Maintain Pyrimidine Synthesis and Survival in p53-Deficient Cancer Cells Exposed to Metabolic Stress

scientific article published on 19 November 2019

MiR-205-driven downregulation of cholesterol biosynthesis through SQLE-inhibition identifies therapeutic vulnerability in aggressive prostate cancer

artículo científico publicado en 2021

Modulation of cellular migration and survival by c-Myc through the downregulation of urokinase (uPA) and uPA receptor

artículo científico publicado en 2010

NFATc1 controls the cytotoxicity of CD8+ T cells

artículo científico publicado en 2017

Navigating gene expression using microarrays--a technology review

artículo científico publicado en 2001

Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways.

artículo científico publicado en 2018

PKB/Akt induces transcription of enzymes involved in cholesterol and fatty acid biosynthesis via activation of SREBP.

artículo científico publicado en 2005

Raf induces TGFbeta production while blocking its apoptotic but not invasive responses: a mechanism leading to increased malignancy in epithelial cells

artículo científico publicado en 2000

Regulation of Metabolic Activity by p53.

artículo científico publicado en 2017

Regulation of cyclin E gene expression by the human papillomavirus type 16 E7 oncoprotein.

artículo científico publicado en 1999

Regulation of the SREBP transcription factors by mTORC1.

scientific article published on April 2011

SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth

artículo científico publicado en 2008

SREBP maintains lipid biosynthesis and viability of cancer cells under lipid- and oxygen-deprived conditions and defines a gene signature associated with poor survival in glioblastoma multiforme

artículo científico

Systematic Analysis Reveals that Cancer Mutations Converge on Deregulated Metabolism of Arachidonate and Xenobiotics

artículo científico publicado en 2016

Targeting cancer metabolism--aiming at a tumour's sweet-spot

artículo científico

The Role of Glucose and Lipid Metabolism in Growth and Survival of Cancer Cells

artículo científico publicado en 2016

The big picture: exploring the metabolic cross-talk in cancer

The forkhead transcription factor FOXO3a increases phosphoinositide-3 kinase/Akt activity in drug-resistant leukemic cells through induction of PIK3CA expression

artículo científico publicado en 2008

The glutathione redox system is essential to prevent ferroptosis caused by impaired lipid metabolism in clear cell renal cell carcinoma

scientific article published on 05 June 2018

The kinase PKD3 provides negative feedback on cholesterol and triglyceride synthesis by suppressing insulin signaling

scientific article published on 06 August 2019

The multifaceted roles of fatty acid synthesis in cancer

artículo científico publicado en 2016

The transcriptional response to Raf activation is almost completely dependent on Mitogen-activated Protein Kinase Kinase activity and shows a major autocrine component

artículo científico publicado en 2004

mTORC1 regulates cell survival under glucose starvation through 4EBP1/2-mediated translational reprogramming of fatty acid metabolism

artículo científico publicado en 2024

Lista de obras de Almut Schulze

3D Growth of Cancer Cells Elicits Sensitivity to Kinase Inhibitors but Not Lipid Metabolism Modifiers

6-Phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 is essential for p53-null cancer cells.

A MYC-GCN2-eIF2α negative feedback loop limits protein synthesis to prevent MYC-dependent apoptosis in colorectal cancer

A computational study of the Warburg effect identifies metabolic targets inhibiting cancer migration

A fresh look at cancer metabolism in a historical setting ⬇️

A new player in the orchestra of cell growth: SREBP activity is regulated by mTORC1 and contributes to the regulation of cell and organ size

Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress

Activation of cyclin A gene expression by the cyclin encoded by human herpesvirus-8.

Analysis of the transcriptional program induced by Raf in epithelial cells

Anchorage-dependent transcription of the cyclin A gene

Antagonism between FOXO and MYC Regulates Cellular Powerhouse

Cathepsin Inhibition Modulates Metabolism and Polarization of Tumor-Associated Macrophages

Cell cycle regulation of the cyclin A gene promoter is mediated by a variant E2F site

Cellular fatty acid metabolism and cancer

Cholesteryl esters: fueling the fury of prostate cancer.

Direct control of caveolin-1 expression by FOXO transcription factors

Erratum: Corrigendum: How cancer metabolism is tuned for proliferation and vulnerable to disruption

FOXO3a regulates reactive oxygen metabolism by inhibiting mitochondrial gene expression

Fatty acid uptake and lipid storage induced by HIF-1α contribute to cell growth and survival after hypoxia-reoxygenation

Flicking the Warburg Switch—Tyrosine Phosphorylation of Pyruvate Dehydrogenase Kinase Regulates Mitochondrial Activity in Cancer Cells ⬇️

Flux balance analysis predicts essential genes in clear cell renal cell carcinoma metabolism

Functional metabolic screen identifies 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 as an important regulator of prostate cancer cell survival.

Functional screening identifies MCT4 as a key regulator of breast cancer cell metabolism and survival

Genetic ablation of S6-kinase does not prevent processing of SREBP1

Genome-wide analysis of FOXO3 mediated transcription regulation through RNA polymerase II profiling

Glycolysis back in the limelight: systemic targeting of HK2 blocks tumor growth

Hooked on fat: the role of lipid synthesis in cancer metabolism and tumour development

How cancer metabolism is tuned for proliferation and vulnerable to disruption ⬇️

Induction of Mxi1-SR alpha by FOXO3a contributes to repression of Myc-dependent gene expression

Involvement of MINK, a Ste20 family kinase, in Ras oncogene-induced growth arrest in human ovarian surface epithelial cells

LXRα activation and Raf inhibition trigger lethal lipotoxicity in liver cancer

Linking Glycogen and Senescence in Cancer Cells ⬇️

Lipid desaturation - the next step in targeting lipogenesis in cancer?

Lipid metabolism in cancer

Metabotypes of breast cancer cell lines revealed by non-targeted metabolomics

Mevalonate Pathway Provides Ubiquinone to Maintain Pyrimidine Synthesis and Survival in p53-Deficient Cancer Cells Exposed to Metabolic Stress

MiR-205-driven downregulation of cholesterol biosynthesis through SQLE-inhibition identifies therapeutic vulnerability in aggressive prostate cancer

Modulation of cellular migration and survival by c-Myc through the downregulation of urokinase (uPA) and uPA receptor

NFATc1 controls the cytotoxicity of CD8+ T cells

Navigating gene expression using microarrays--a technology review

Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways.

PKB/Akt induces transcription of enzymes involved in cholesterol and fatty acid biosynthesis via activation of SREBP.

Raf induces TGFbeta production while blocking its apoptotic but not invasive responses: a mechanism leading to increased malignancy in epithelial cells

Regulation of Metabolic Activity by p53.

Regulation of cyclin E gene expression by the human papillomavirus type 16 E7 oncoprotein.

Regulation of the SREBP transcription factors by mTORC1.

SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth

SREBP maintains lipid biosynthesis and viability of cancer cells under lipid- and oxygen-deprived conditions and defines a gene signature associated with poor survival in glioblastoma multiforme

Systematic Analysis Reveals that Cancer Mutations Converge on Deregulated Metabolism of Arachidonate and Xenobiotics

Targeting cancer metabolism--aiming at a tumour's sweet-spot

The Role of Glucose and Lipid Metabolism in Growth and Survival of Cancer Cells

The big picture: exploring the metabolic cross-talk in cancer

The forkhead transcription factor FOXO3a increases phosphoinositide-3 kinase/Akt activity in drug-resistant leukemic cells through induction of PIK3CA expression

The glutathione redox system is essential to prevent ferroptosis caused by impaired lipid metabolism in clear cell renal cell carcinoma

The kinase PKD3 provides negative feedback on cholesterol and triglyceride synthesis by suppressing insulin signaling

The multifaceted roles of fatty acid synthesis in cancer

The transcriptional response to Raf activation is almost completely dependent on Mitogen-activated Protein Kinase Kinase activity and shows a major autocrine component

mTORC1 regulates cell survival under glucose starvation through 4EBP1/2-mediated translational reprogramming of fatty acid metabolism