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Lista de obras de Per Svenningsson

5-HT1B receptor imaging and cognition: a positron emission tomography study in control subjects and Parkinson's disease patients

artículo científico

A role for p11 in the antidepressant action of brain-derived neurotrophic factor

artículo científico publicado en 2010

A twelve-year follow-up study on a case of early-onset parkinsonism preceding clinical manifestation of Gaucher disease

artículo científico publicado en 2011

Abstract # 1792 Peripheral inflammatory mediators and p11 levels in peripheral blood mononuclear cells from patients with Parkinson’s disease

scholarly article by H.F. Green et al published October 2016 in Brain, Behavior, and Immunity

Activation of adenosine A2A and dopamine D1 receptors stimulates cyclic AMP-dependent phosphorylation of DARPP-32 in distinct populations of striatal projection neurons

artículo científico publicado en 1998

Activation of dopamine D2 receptors decreases DARPP-32 phosphorylation in striatonigral and striatopallidal projection neurons via different mechanisms

artículo científico publicado en 1999

Adenosine and brain function

artículo científico publicado en 2005

Alterations in 5-HT1B receptor function by p11 in depression-like states

artículo científico publicado en 2006

Alterations of p11 in brain tissue and peripheral blood leukocytes in Parkinson's disease

artículo científico publicado en 2017

An automated method for scanning LC-MS data sets for significant peptides and proteins, including quantitative profiling and interactive confirmation

artículo científico publicado en 2007

Antagonism of adenosine A2A receptors underlies the behavioural activating effect of caffeine and is associated with reduced expression of messenger RNA for NGFI-A and NGFI-B in caudate-putamen and nucleus accumbens

artículo científico publicado en 1997

Antidepressant-like properties of sarizotan in experimental Parkinsonism

artículo científico publicado en 2011

Antidepressants reverse the attenuation of the neurotrophic MEK/MAPK cascade in frontal cortex by elevated platform stress; reversal of effects on LTP is associated with GluA1 phosphorylation

artículo científico publicado en 2008

Asymmetric dopaminergic degeneration and levodopa alter functional corticostriatal connectivity bilaterally in experimental parkinsonism

artículo científico publicado en 2017

Attenuated beta rebound to proprioceptive afferent feedback in Parkinson's disease

scholarly article published 30 May 2018

Behavioral and biochemical responses to d-amphetamine in MCH1 receptor knockout mice

artículo científico publicado en 2008

Bidirectional regulation of emotional memory by 5-HT1B receptors involves hippocampal p11.

artículo científico publicado en 2012

Caffeine mimics the effect of a dopamine D2/3 receptor agonist on the expression of immediate early genes in globus pallidus

artículo científico publicado en 1997

Caveolin-1 interacts with alpha-synuclein and mediates toxic actions of cellular alpha-synuclein overexpression

artículo científico publicado en 2011

Cell type-specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs

artículo científico publicado en 2008

Cell- and region-specific expression of depression-related protein p11 (S100a10) in the brain

artículo científico publicado en 2016

Cellular distribution of adenosine A2A receptor mRNA in the primate striatum

artículo científico publicado en 1998

Cellular localization and function of DARPP-32 in the rodent retina

artículo científico publicado en 2007

Changes on 5-HT2 receptor mRNAs in striatum and subthalamic nucleus in Parkinson's disease model

artículo científico publicado en 2007

Clinical and genetic characteristics of late-onset Huntington's disease

artículo científico publicado en 2018

Clozapine counteracts a ketamine-induced depression of hippocampal-prefrontal neuroplasticity and alters signaling pathway phosphorylation

artículo científico publicado en 2017

Co-expression of serotonin 5-HT(1B) and 5-HT(4) receptors in p11 containing cells in cerebral cortex, hippocampus, caudate-putamen and cerebellum

artículo científico publicado en 2011

Controlled-pH tissue cleanup protocol for signal enhancement of small molecule drugs analyzed by MALDI-MS imaging

artículo científico publicado en 2012

Correlations Between Methionine Cycle Metabolism, COMT Genotype, and Polyneuropathy in L-Dopa Treated Parkinson's Disease: A Preliminary Cross-Sectional Study

artículo científico publicado en 2017

Coupling surface plasmon resonance to mass spectrometry to discover novel protein-protein interactions

artículo científico publicado en 2009

Cyclin-dependent kinase 5 regulates dopaminergic and glutamatergic transmission in the striatum

scientific journal article

DARPP-32 Mediates the Actions of Multiple Drugs of Abuse

DARPP-32 mediates serotonergic neurotransmission in the forebrain

artículo científico publicado en 2002

DARPP-32 mediates the actions of multiple drugs of abuse

artículo científico publicado en 2005

DARPP-32: an integrator of neurotransmission

artículo científico publicado en 2004

Decreased Prosaposin and Progranulin in the Cingulate Cortex Are Associated with Schizophrenia Pathophysiology

artículo científico publicado en 2022

Decreased striatal levels of PEP-19 following MPTP lesion in the mouse

artículo científico publicado en 2006

Depressive-like phenotype induced by AAV-mediated overexpression of human α-synuclein in midbrain dopaminergic neurons

artículo científico publicado en 2015

Deuterated matrix-assisted laser desorption ionization matrix uncovers masked mass spectrometry imaging signals of small molecules

artículo científico publicado en 2012

Diffusion tensor fiber tractography of the olfactory tract ⬇️

artículo científico publicado el 17 de septiembre de 2010

Distinct roles for spinophilin and neurabin in dopamine-mediated plasticity

artículo científico publicado en 2006

Distribution of adenosine receptors in the postmortem human brain: an extended autoradiographic study

artículo científico publicado en 1997

Distribution, biochemistry and function of striatal adenosine A2A receptors

artículo científico publicado en 1999

Distribution, level, pharmacology, regulation, and signaling of 5‐HT6 receptors in rats and marmosets with special reference to an experimental model of parkinsonism ⬇️

artículo científico publicado el 15 de junio de 2011

Diverse psychotomimetics act through a common signaling pathway

artículo científico publicado en 2003

Dopamine D(1) receptor-induced gene transcription is modulated by DARPP-32

scientific journal article

Dopamine-adenosine interactions in the striatum and the globus pallidus: inhibition of striatopallidal neurons through either D2 or A2A receptors enhances D1 receptor-mediated effects on c-fos expression.

artículo científico publicado en 1997

Effect of methylphenidate on dopamine/DARPP signalling in adult, but not young, mice

artículo científico publicado en 2003

Effect of the myeloperoxidase inhibitor AZD3241 on microglia: a PET study in Parkinson's disease

artículo científico publicado en 2015

Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5.

artículo científico publicado en 2001

Effects of lithium and aripiprazole on brain stimulation reward and neuroplasticity markers in the limbic forebrain.

artículo científico publicado en 2013

Eltoprazine counteracts l-DOPA-induced dyskinesias in Parkinson's disease: a dose-finding study

artículo científico publicado en 2015

Emotional memory impairments in a genetic rat model of depression: involvement of 5-HT/MEK/Arc signaling in restoration

artículo científico publicado en 2011

Emotional memory impairments induced by AAV-mediated overexpression of human α-synuclein in dopaminergic neurons of the ventral tegmental area

artículo científico publicado en 2015

Epigenetics and energetics in ventral hippocampus mediate rapid antidepressant action: Implications for treatment resistance

artículo científico publicado en 2016

Estradiol affects spinophilin protein differently in gonadectomized males and females

artículo científico

Evidence for a role of the 5-HT1B receptor and its adaptor protein, p11, in L-DOPA treatment of an animal model of Parkinsonism

artículo científico publicado en 2008

Evidence that the increase in striatal c-fos following acute high-dose caffeine is not due to direct interaction with striatal adenosine receptors

artículo científico publicado en 1992

Feasibility Aspects of Exploring Exercise-Induced Neuroplasticity in Parkinson's Disease: A Pilot Randomized Controlled Trial

artículo científico publicado en 2020

Folding Underlies Bidirectional Role of GPR37/Pael-R in Parkinson Disease

artículo científico publicado en 2017

Functional GPR37 trafficking protects against toxicity induced by 6-OHDA, MPP+ or rotenone in a catecholaminergic cell line

artículo científico publicado en 2012

GPR37 protein trafficking to the plasma membrane regulated by prosaposin and GM1 gangliosides promotes cell viability

artículo científico publicado en 2013

Gene therapy blockade of dorsal striatal p11 improves motor function and dyskinesia in parkinsonian mice

artículo científico publicado en 2016

Genetic Variations and mRNA Expression of NRF2 in Parkinson's Disease

artículo científico publicado en 2017

Genetic evidence for role of integration of fast and slow neurotransmission in schizophrenia

artículo científico publicado en 2017

Heat stabilization of the tissue proteome: a new technology for improved proteomics

artículo científico publicado en 2009

How can drug discovery for psychiatric disorders be improved?

artículo científico publicado en 2007

Identification of protein-protein interactions by surface plasmon resonance followed by mass spectrometry

artículo científico publicado en 2011

In search of the mechanisms of ketamine’s antidepressant effects: How robust is the evidence behind the mTor activation hypothesis

Increased expression of NGFI-A mRNA in the rat striatum following burst stimulation of the medial forebrain bundle

artículo científico publicado en 1997

Increased expression of c-jun, junB, AP-1, and preproenkephalin mRNA in rat striatum following a single injection of caffeine.

artículo científico publicado en 1995

Increased levels of ubiquitin in the 6-OHDA-lesioned striatum of rats

artículo científico publicado en 2005

Increased striatal mRNA and protein levels of the immunophilin FKBP-12 in experimental Parkinson's disease and identification of FKBP-12-binding proteins

scientific journal article

Involvement of AMPA receptor phosphorylation in antidepressant actions with special reference to tianeptine

artículo científico publicado en 2007

Involvement of DARPP-32 phosphorylation in the stimulant action of caffeine

artículo científico publicado en 2002

Involvement of a c-fos-dependent mechanism in caffeine-induced expression of the preprotachykinin A and neurotensin/neuromedin N genes in rat striatum

artículo científico publicado en 1997

Involvement of striatal and extrastriatal DARPP-32 in biochemical and behavioral effects of fluoxetine (Prozac).

artículo científico publicado en 2002

Lurasidone and fluoxetine reduce novelty-induced hypophagia and NMDA receptor subunit and PSD-95 expression in mouse brain

artículo científico publicado en 2015

MRI Diffusion in Parkinson's Disease: Using the Technique's Inherent Directional Information to Study the Olfactory Bulb and Substantia Nigra ⬇️

artículo científico publicado el 1 de enero de 2012

Mass Spectrometry Imaging, an Emerging Technology in Neuropsychopharmacology ⬇️

artículo científico publicado el 21 de agosto de 2013

Methylenedioxymethamphetamine (MDMA)

article

Modulation of monoamine receptors by adaptor proteins and lipid rafts: role in some effects of centrally acting drugs and therapeutic agents

artículo científico publicado en 2011

Molecular profiling of experimental Parkinson's disease: direct analysis of peptides and proteins on brain tissue sections by MALDI mass spectrometry

artículo científico publicado en 2004

Monoamines, BDNF, IL-6 and corticosterone in CSF in patients with Parkinson's disease and major depression

artículo científico publicado en 2009

Mu- and delta-opioid receptor agonists inhibit DARPP-32 phosphorylation in distinct populations of striatal projection neurons

artículo científico publicado en 1999

NMDA receptor antagonists ketamine and Ro25-6981 inhibit evoked release of glutamate in vivo in the subiculum

artículo científico publicado en 2014

Neurogenic effects of fluoxetine are attenuated in p11 (S100A10) knockout mice

artículo científico publicado en 2010

Neurokinin B/NK3 receptors exert feedback inhibition on L-DOPA actions in the 6-OHDA lesion rat model of Parkinson's disease

artículo científico publicado en 2008

Neuropeptide Y and Calcitonin Gene-Related Peptide in Cerebrospinal Fluid in Parkinson's Disease with Comorbid Depression versus Patients with Major Depressive Disorder

artículo científico publicado en 2017

Neuropeptidomics of mouse hypothalamus after imipramine treatment reveal somatostatin as a potential mediator of antidepressant effects

artículo científico publicado en 2011

Neuropeptidomics: MS applied to the discovery of novel peptides from the brain

artículo científico publicado en 2007

Nigrostriatal dopamine transporter availability in early Parkinson's disease

artículo científico publicado en 2018

No correlation between serotonin and its metabolite 5-HIAA in the cerebrospinal fluid and [(11) C]AZ10419369 binding measured with PET in healthy volunteers

artículo científico publicado en 2014

Novel Imaging Biomarkers for Huntington's Disease and Other Hereditary Choreas

artículo científico publicado en 2018

Novel Treatment Opportunities Against Cognitive Impairment in Parkinson's Disease with an Emphasis on Diabetes-Related Pathways

scientific article published on 01 February 2019

Optimal Acquisition Time Window and Simplified Quantification of Dopamine Transporter Availability Using 18F-FE-PE2I in Healthy Controls and Parkinson Disease Patients

artículo científico publicado en 2016

Overexpression of α-synuclein simultaneously increases glutamate NMDA receptor phosphorylation and reduces glucocerebrosidase activity

artículo científico publicado en 2015

P.1.006 Neurogenic and chronic behavioural effects of fluoxetine are attenuated in p11 KO mice

P.2.b.019 Ablated neurogenic response to fluoxetine in female p11 knockout mice

P11 deficiency increases stress reactivity along with HPA axis and autonomic hyperresponsiveness

scientific article published on 01 October 2020

Peptidomics-Based Discovery of Novel Neuropeptides ⬇️

artículo científico publicado el 1 de marzo de 2003

Phactrs 1-4: A family of protein phosphatase 1 and actin regulatory proteins

artículo científico publicado en 2004

Pharmacological or genetic blockade of the dopamine D3 receptor increases cell proliferation in the hippocampus of adult mice

artículo científico publicado en 2012

Phosphorylation of DARPP-32 at Threonine-34 is required for cocaine action

artículo científico publicado en 2006

Positron emission tomography imaging of 5-hydroxytryptamine1B receptors in Parkinson's disease

artículo científico publicado en 2013

Protection of stress-induced impairment of hippocampal/prefrontal LTP through blockade of glucocorticoid receptors: implication of MEK signaling

artículo científico publicado en 2008

Quantitative Analysis of ¹⁸F-(E)-N-(3-Iodoprop-2-Enyl)-2β-Carbofluoroethoxy-3β-(4'-Methyl-Phenyl) Nortropane Binding to the Dopamine Transporter in Parkinson Disease

artículo científico publicado en 2015

Quantitative mapping shows that serotonin rather than dopamine receptor mRNA expressions are affected after repeated intermittent administration of MDMA in rat brain

artículo científico publicado en 2006

Reduced phosphorylation of GluA1 subunits relates to anxiety-like behaviours in mice

artículo científico publicado en 2013

Regional differences in the ability of caffeine to affect haloperidol-induced striatal c-fos mRNA expression in the rat.

artículo científico publicado en 1998

Regulation of a protein phosphatase cascade allows convergent dopamine and glutamate signals to activate ERK in the striatum

artículo científico publicado en 2004

Regulation of serotonin receptor function in the nervous system by lipid rafts and adaptor proteins

artículo científico publicado en 2010

Regulation of the phosphorylation of the dopamine- and cAMP-regulated phosphoprotein of 32 kDa in vivo by dopamine D1, dopamine D2, and adenosine A2A receptors

artículo científico publicado en 2000

Repeated l-DOPA treatment increases c-fos and BDNF mRNAs in the subthalamic nucleus in the 6-OHDA rat model of Parkinson's disease

artículo científico publicado en 2006

Reversal of depressed behaviors in mice by p11 gene therapy in the nucleus accumbens

artículo científico publicado en 2010

Ropinirole regulates emotionality and neuronal activity markers in the limbic forebrain

artículo científico publicado en 2014

S100B interacts with the serotonin 5-HT7 receptor to regulate a depressive-like behavior

artículo científico publicado en 2015

S100B overexpressing mutant mice exhibit prolonged behavioural and biochemical responses towards repeated intermittent binge treatments with MDMA.

artículo científico publicado en 2008

S33138 [N-[4-[2-[(3aS,9bR)-8-cyano-1,3a,4,9b-tetrahydro[1]-benzopyrano[3,4-c]pyrrol-2(3H)-yl)-ethyl]phenylacetamide], a preferential dopamine D3 versus D2 receptor antagonist and potential antipsychotic agent. II. A neurochemical, electrophysiologic

artículo científico publicado en 2007

Safety and tolerability of IRL790 in Parkinson's disease with levodopa-induced dyskinesia-a phase 1b trial

scholarly article by Per Svenningsson et al published 2018 in NPJ Parkinson's disease

Safety and tolerability of intracerebroventricular PDGF-BB in Parkinson's disease patients

artículo científico publicado en 2015

Serotonin-1A receptors in major depression quantified using PET: Controversies, confounds, and recommendations ⬇️

artículo científico publicado el 25 de noviembre de 2011

Severe deficiencies in dopamine signaling in presymptomatic Huntington's disease mice

artículo científico publicado en 2000

Striatal adenosine A2A receptors--where are they? What do they do?

artículo científico publicado en 1998

Striatal alterations of secretogranin-1, somatostatin, prodynorphin, and cholecystokinin peptides in an experimental mouse model of Parkinson disease

artículo científico publicado en 2009

Strong association between glucocerebrosidase mutations and Parkinson's disease in Sweden

artículo científico publicado en 2016

Studies of depression-related states in animal models of Parkinsonism

artículo científico publicado en 2012

The Rho-specific GEF Lfc interacts with neurabin and spinophilin to regulate dendritic spine morphology

scientific journal article

The role of DARPP-32 in the actions of drugs of abuse

artículo científico publicado en 2004

The significance of biochemical and molecular sample integrity in brain proteomics and peptidomics: stathmin 2-20 and peptides as sample quality indicators

artículo científico publicado en 2007

The stimulatory action and the development of tolerance to caffeine is associated with alterations in gene expression in specific brain regions.

artículo científico publicado en 1999

Tianeptine potentiates AMPA receptors by activating CaMKII and PKA via the p38, p42/44 MAPK and JNK pathways

artículo científico publicado en 2011

Transcription factor Nurr1 maintains fiber integrity and nuclear-encoded mitochondrial gene expression in dopamine neurons

artículo científico publicado en 2013

Use of surface plasmon resonance coupled with mass spectrometry reveals an interaction between the voltage-gated sodium channel type X alpha-subunit and caveolin-1.

artículo científico publicado en 2008

p11 (S100A10)--an inducible adaptor protein that modulates neuronal functions

artículo científico publicado en 2006

p11 and its role in depression and therapeutic responses to antidepressants

artículo científico publicado en 2013

p11 modulates L-DOPA therapeutic effects and dyskinesia via distinct cell types in experimental Parkinsonism

artículo científico publicado en 2016

α-Synuclein induced toxicity in brain stem serotonin neurons mediated by an AAV vector driven by the tryptophan hydroxylase promoter

artículo científico publicado en 2016

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