Filtros de búsqueda

Lista de obras de David Klenerman

A Model Corrosion Inhibitor for in Situ Spectroscopic Studies

article

A Reversible pH-Driven DNA Nanoswitch Array

artículo científico publicado en 2006

A Simple Nanomixer for Single-Molecule Kinetics Measurements

A Simple Nanomixer for Single-Molecule Kinetics Measurements

scholarly article by Samuel S. White et al published 20 November 2006 in Angewandte Chemie International Edition

A Simple Voltage Controlled Enzymatic Nanoreactor Produced in the Tip of a Nanopipet

article by Andreas Bruckbauer et al published October 2004 in Nano Letters

A cell topography-based mechanism for ligand discrimination by the T cell receptor

scientific article published on 20 June 2019

A chelating dendritic ligand capped quantum dot: preparation, surface passivation, bioconjugation and specific DNA detection.

artículo científico publicado en 2010

A compact functional quantum Dot-DNA conjugate: preparation, hybridization, and specific label-free DNA detection ⬇️

artículo científico publicado en 2008

A hybrid scanning mode for fast scanning ion conductance microscopy (SICM) imaging

artículo científico publicado en 2012

A mechanistic model of tau amyloid aggregation based on direct observation of oligomers

artículo científico publicado en 2015

A microfluidic device for the hydrodynamic immobilisation of living fission yeast cells for super-resolution imaging

artículo científico publicado en 2014

A novel light source for SICM-SNOM of living cells.

artículo científico publicado en 2003

A quantitative comparison of single-dye tracking analysis tools using Monte Carlo simulations

artículo científico publicado en 2013

A renewable nanosensor based on a glass nanopipette

artículo científico publicado en 2006

A second-harmonic generation study of a corrosion inhibitor on a mild steel electrode

A single gD glycoprotein can mediate infection by Herpes simplex virus

artículo científico publicado en 2013

Accurate whole human genome sequencing using reversible terminator chemistry

artículo científico publicado en 2008

Activation of Toll-like receptors nucleates assembly of the MyDDosome signaling hub.

artículo científico publicado en 2018

Aggregated α-synuclein and complex I deficiency: exploration of their relationship in differentiated neurons

artículo científico publicado en 2015

Aldosterone acts via an ATP autocrine/paracrine system: the Edelman ATP hypothesis revisited

artículo científico publicado en 2005

Alpha-Synuclein Oligomers Interact with Metal Ions to Induce Oxidative Stress and Neuronal Death in Parkinson's Disease

artículo científico publicado en 2015

Amyloid-β oligomers are sequestered by both intracellular and extracellular chaperones

scientific journal article

An addressable antibody nanoarray produced on a nanostructured surface

artículo científico publicado en 2004

An alternative mechanism of clathrin-coated pit closure revealed by ion conductance microscopy

artículo científico publicado en 2012

Analysis of human telomerase activity and function by two color single molecule coincidence fluorescence spectroscopy

artículo científico publicado en 2006

Basolateral P2X4-like receptors regulate the extracellular ATP-stimulated epithelial Na+ channel activity in renal epithelia.

artículo científico publicado en 2007

Bayesian inference for improved single molecule fluorescence tracking

artículo científico publicado en 2008

Bayesian inference of accurate population sizes and FRET efficiencies from single diffusing biomolecules

artículo científico publicado en 2014

Building Three-Dimensional Surface Biological Assemblies on the Nanometer Scale

Building three-dimensional nanostructures with active enzymes by surface templated layer-by-layer assembly

artículo científico publicado en 2006

CHAPTER 2. Fluorophore Conjugates for Single Molecule Work

Characterization and application of controllable local chemical changes produced by reagent delivery from a nanopipet

artículo científico publicado en 2008

Characterization of a Single Molecule DNA Switch in Free Solution

article by Samuel S. White et al published September 2006 in Journal of the American Chemical Society

Characterization of a novel light source for simultaneous optical and scanning ion conductance microscopy

artículo científico publicado en 2002

Contact-free scanning and imaging with the scanning ion conductance microscope

artículo científico publicado en 2014

Correction to: Picomolar concentrations of oligomeric alpha-synuclein sensitizes TLR4 to play an initiating role in Parkinson's disease pathogenesis

artículo científico publicado en 2019

Corrigendum: Multifunctional Nanoprobes for Nanoscale Chemical Imaging and Localized Chemical Delivery at Surfaces and Interfaces

scholarly article by Yasufumi Takahashi et al published 2 July 2014 in Angewandte Chemie International Edition

Determination of the fraction and stoichiometry of femtomolar levels of biomolecular complexes in an excess of monomer using single-molecule, two-color coincidence detection

artículo científico publicado en 2006

Different soluble aggregates of Aβ42 can give rise to cellular toxicity through different mechanisms

article

Direct and quantitative detection of bacteriophage by "hearing" surface detachment using a quartz crystal microbalance

artículo científico publicado en 2001

Direct and sensitive detection of a human virus by rupture event scanning.

artículo científico publicado en 2001

Direct characterization of amyloidogenic oligomers by single-molecule fluorescence

artículo científico publicado en 2008

Direct measurement of lipid membrane disruption connects kinetics and toxicity of Aβ42 aggregation

artículo científico publicado en 2020

Direct observation of the interconversion of normal and toxic forms of α-synuclein

artículo científico publicado en 2012

DySCo: quantitating associations of membrane proteins using two-color single-molecule tracking.

artículo científico publicado en 2009

Dynamic assembly of surface structures in living cells

artículo científico publicado en 2003

Effects of mechanical compression on the vibrational spectrum of a self-assembled monolayer

article

Electrochemical nanoprobes for single-cell analysis ⬇️

artículo científico publicado en 2014

Endocytic pathways: combined scanning ion conductance and surface confocal microscopy study

artículo científico publicado en 2008

Erratum: Corrigendum: Nanoscale live-cell imaging using hopping probe ion conductance microscopy

article

Erratum: Single-molecule analysis of human telomerase monomer

scholarly article published in Nature Chemical Biology

Evidence for resonance optical trapping of individual fluorophore-labeled antibodies using single molecule fluorescence spectroscopy

artículo científico publicado en 2006

Evidence of an intermediate and parallel pathways in protein unfolding from single-molecule fluorescence.

artículo científico publicado en 2008

Fabrication of Three-Dimensional Surface Structures with Highly Fluorescent Quantum Dots by Surface-Templated Layer-by-Layer Assembly

Fast flow microfluidics and single-molecule fluorescence for the rapid characterization of α-synuclein oligomers

artículo científico publicado en 2015

Fluorescence Coincidence Spectroscopy for Single-Molecule Fluorescence Resonance Energy-Transfer Measurements

artículo científico publicado en 2008

Fluorescence resonance energy transfer between a quantum dot donor and a dye acceptor attached to DNA.

artículo científico publicado en 2005

Fluorescence studies of single biomolecules.

artículo científico publicado en 2004

High resolution imaging using scanning ion conductance microscopy with improved distance feedback control

High-resolution label-free 3D mapping of extracellular pH of single living cells

scientific article published on 06 December 2019

Highly rapid amplification-free and quantitative DNA imaging assay

artículo científico publicado en 2013

How effective is internal excitation in promoting the HCl + 1,3-butadiene addition reaction?

article

Hsp70 inhibits the nucleation and elongation of tau and sequesters tau aggregates with high affinity

artículo científico publicado en 2018

Hydrodynamic trapping of molecules in lipid bilayers

artículo científico publicado en 2012

Hyperphosphorylated tau self-assembles into amorphous aggregates eliciting TLR4-dependent responses

artículo científico publicado en 2022

Identification of a new RNA.RNA interaction site for human telomerase RNA (hTR): structural implications for hTR accumulation and a dyskeratosis congenita point mutation ⬇️

artículo científico publicado en 2003

Imaging and characterisation of the surface of live cells

artículo científico publicado en 2011

Imaging proteins in membranes of living cells by high-resolution scanning ion conductance microscopy.

artículo científico publicado en 2006

Imaging single nanoparticle interactions with human lung cells using fast ion conductance microscopy.

artículo científico publicado en 2014

Imaging single virus particles on the surface of cell membranes by high-resolution scanning surface confocal microscopy

artículo científico publicado en 2008

Imaging the cell surface and its organization down to the level of single molecules

artículo científico

In-situ studies of polycrystalline copper during methanol synthesis at high pressure using sum frequency generation at surfaces

Increased Secondary Nucleation Underlies Accelerated Aggregation of the Four-Residue N-Terminally Truncated Aβ42 Species Aβ5-42

scientific article published on 08 March 2019

Individual Molecules of Dye-Labeled DNA Act as a Reversible Two-Color Switch upon Application of an Electric Field

Individual Molecules of Dye-Labeled DNA Act as a Reversible Two-Color Switch upon Application of an Electric Field

scholarly article by Samuel S. White et al published 12 November 2004 in Angewandte Chemie International Edition

Influence of the foundation layer on the layer-by-layer assembly of poly-L-lysine and poly(styrenesulfonate) and its usage in the fabrication of 3D microscale features.

artículo científico publicado en 2004

Infrared chemiluminescence studies using a SISAM spectrometer. Reactions producing vibrationally excited OH

article

Infrared chemiluminescence using a SISAM spectrometer. Reactions producing vibrationally excited HF

article

Inhibiting the Ca2+ Influx Induced by Human CSF.

artículo científico publicado en 2017

Intracellular oligomeric amyloid-beta rapidly regulates GluA1 subunit of AMPA receptor in the hippocampus.

artículo científico publicado en 2015

Investigating a quadruplex-ligand interaction by unfolding kinetics

artículo científico

Kinetic diversity of amyloid oligomers

scientific article published on 15 May 2020

Kinetic model of the aggregation of alpha-synuclein provides insights into prion-like spreading

artículo científico publicado en 2016

Kinetics of Unfolding the Human Telomeric DNA Quadruplex Using a PNA Trap

scientific article published in 2003

Label-Free Measurements of the Diffusivity of Molecules in Lipid Membranes

article published in 2014

Lipid peroxidation is essential for α-synuclein-induced cell death

artículo científico publicado en 2015

Local delivery of molecules from a nanopipette for quantitative receptor mapping on live cells.

artículo científico publicado en 2013

Localized and non-contact mechanical stimulation of dorsal root ganglion sensory neurons using scanning ion conductance microscopy

artículo científico publicado en 2006

Macroscopic 2D Networks Self-Assembled from Nanometer-Sized Protein/DNA Complexes

Mapping Surface Hydrophobicity of α-Synuclein Oligomers at the Nanoscale

artículo científico publicado en 2018

Measurements of the Adsorption Kinetics of a Cationic Surfactant in a Liquid Jet by Ellipsometry

Measuring single-molecule nucleic acid dynamics in solution by two-color filtered ratiometric fluorescence correlation spectroscopy

artículo científico publicado en 2004

Mechanistic studies of the corrosion inhibitor oleic imidazoline

Molecule by molecule direct and quantitative counting of antibody-protein complexes in solution

artículo científico publicado en 2004

Multicomponent submicron features of biomolecules created by voltage controlled deposition from a nanopipet

artículo científico publicado en 2003

Multifunctional nanoprobes for nanoscale chemical imaging and localized chemical delivery at surfaces and interfaces.

artículo científico publicado en 2011

Nanopipette delivery of individual molecules to cellular compartments for single-molecule fluorescence tracking

artículo científico publicado en 2007

Nanopore extended field-effect transistor for selective single-molecule biosensing.

artículo científico publicado en 2017

Nanoscale live-cell imaging using hopping probe ion conductance microscopy

artículo científico publicado en 2009

Nanoscale pipetting for controlled chemistry in small arrayed water droplets using a double-barrel pipet

artículo científico publicado en 2006

Nanoscale-targeted patch-clamp recordings of functional presynaptic ion channels

artículo científico publicado en 2013

Nanoscopic Characterisation of Individual Endogenous Protein Aggregates in Human Neuronal Cells

scientific article published on 11 September 2018

Non-Arrhenius kinetics for the loop closure of a DNA hairpin.

artículo científico publicado en 2001

Non-invasive imaging of stem cells by scanning ion conductance microscopy: future perspective

artículo científico publicado en 2008

Noncontact measurement of the local mechanical properties of living cells using pressure applied via a pipette

artículo científico publicado en 2008

On-Demand Delivery of Single DNA Molecules Using Nanopipets ⬇️

artículo científico publicado en 2015

Optical Structural Analysis of Individual α-Synuclein Oligomers

Optical structural analysis of individual α-synuclein oligomers

artículo científico publicado en 2018

Optically heterodyned Raman-induced Kerr-effect spectroscopy using a white-light continuum

Optimized threshold selection for single-molecule two-color fluorescence coincidence spectroscopy

artículo científico publicado en 2007

Persistency of corrosion inhibitor films on c-steel under multiphase flow conditions. Part i: the jet-cylinder arrangement

Persistency of corrosion inhibitor films on c-steel under multiphase flow conditions. Part ii: optical shg and electrochemical studies

Picomolar concentrations of oligomeric alpha-synuclein sensitizes TLR4 to play an initiating role in Parkinson's disease pathogenesis

artículo científico publicado en 2018

Pipette-surface interaction: current enhancement and intrinsic force

artículo científico publicado en 2012

Potential biomedical applications of the scanned nanopipette

artículo científico publicado en 2006

Probing neuroserpin polymerization and interaction with amyloid-beta peptides using single molecule fluorescence.

artículo científico publicado en 2009

Programmable Delivery of DNA through a Nanopipet

scientific article published on 01 March 2002

Quantification of DNA-associated proteins inside eukaryotic cells using single-molecule localization microscopy

artículo científico publicado en 2014

Quantifying Co-Oligomer Formation by α-Synuclein

artículo científico publicado en 2018

Quantitative single-molecule microscopy reveals that CENP-A(Cnp1) deposition occurs during G2 in fission yeast.

artículo científico publicado en 2012

RNA conformation in catalytically active human telomerase

artículo científico publicado en 2010

Rare individual amyloid-β oligomers act on astrocytes to initiate neuronal damage

scientific article published on 09 April 2014

Realizing the biological and biomedical potential of nanoscale imaging using a pipette probe

scientific article published on 01 April 2011

Referenced Single-Molecule Measurements Differentiate between GPCR Oligomerization States

artículo científico publicado en 2015

Scanning ion conductance microscopy reveals how a functional renal epithelial monolayer maintains its integrity.

artículo científico publicado en 2005

Scanning ion conductance microscopy: a convergent high-resolution technology for multi-parametric analysis of living cardiovascular cells ⬇️

artículo científico publicado en 2011

Scanning surface confocal microscopy for simultaneous topographical and fluorescence imaging: application to single virus-like particle entry into a cell.

artículo científico publicado en 2002

Second harmonic generation at surfaces applied to corrosion inhibition

article by David Klenerman et al published February 1994 in Corrosion Science

Secondary nucleation and elongation occur at different sites on Alzheimer's amyloid-β aggregates

scientific article published on 17 April 2019

Selective diffusion barriers separate membrane compartments

artículo científico publicado en 2010

Separation and detection of bacteria using rupture event scanning.

artículo científico publicado en 2011

Shedding light on aberrant interactions: A review of modern tools for studying protein aggregates

artículo científico publicado en 2018

Single Molecule Fluorescence under Conditions of Fast Flow

artículo científico publicado en 2011

Single molecule characterization of the interactions between amyloid-β peptides and the membranes of hippocampal cells

artículo científico publicado en 2013

Single-Molecule Characterization of the Interactions between Extracellular Chaperones and Toxic α-Synuclein Oligomers.

artículo científico publicado en 2018

Single-Molecule Imaging of Individual Amyloid Protein Aggregates in Human Biofluids

artículo científico publicado en 2016

Single-molecule FRET reveals hidden complexity in a protein energy landscape.

artículo científico publicado en 2015

Single-molecule FRET studies on alpha-synuclein oligomerization of Parkinson's disease genetically related mutants

artículo científico publicado en 2015

Single-molecule analysis of human telomerase monomer

article

Single-molecule analysis of the human telomerase RNA.dyskerin interaction and the effect of dyskeratosis congenita mutations

artículo científico publicado en 2009

Single-molecule imaging reveals that small amyloid-β1-42 oligomers interact with the cellular prion protein (PrP(C))

artículo científico publicado en 2014

Single-molecule level analysis of the subunit composition of the T cell receptor on live T cells

artículo científico publicado en 2007

Single-molecule measurements of transient biomolecular complexes through microfluidic dilution.

artículo científico publicado en 2013

Single-molecule two-colour coincidence detection to probe biomolecular associations

artículo científico publicado en 2010

Single-molecule visualization of DNA G-quadruplex formation in live cells

artículo científico publicado en 2020

Single‐Molecule Fluorescence Coincidence Spectroscopy and its Application to Resonance Energy Transfer ⬇️

artículo científico publicado el 4 de octubre de 2010

Soluble aggregates present in cerebrospinal fluid change in size and mechanism of toxicity during Alzheimer's disease progression

artículo científico publicado en 2019

Spearhead Nanometric Field-Effect Transistor Sensors for Single-Cell Analysis.

artículo científico publicado en 2016

Structural analysis of the catalytic core of human telomerase RNA by FRET and molecular modeling

artículo científico publicado en 2006

Structural characterization of toxic oligomers that are kinetically trapped during α-synuclein fibril formation.

artículo científico publicado en 2015

Studies of the adsorption of a corrosion inhibitor onto mild steel using surface second-harmonic generation

Studies on the structure and dynamics of the human telomeric G quadruplex by single-molecule fluorescence resonance energy transfer

artículo científico publicado en 2003

Sum Frequency Spectra in the C-H Stretch Region of Adsorbates on Iron

Super-resolution imaging reveals α-synuclein seeded aggregation in SH-SY5Y cells

artículo científico publicado en 2021

Supramolecular organization of the sperm plasma membrane during maturation and capacitation

artículo científico publicado en 2007

Surface conductivity of biological macromolecules measured by nanopipette dielectrophoresis

artículo científico publicado en 2007

Surface-sensitive molecular information on polymers from UV-resonance Raman spectroscopy

artículo científico publicado en 2003

Taking T cells beyond the diffraction limit

artículo científico publicado en 2010

The 2015 super-resolution microscopy roadmap

The BRC repeats of human BRCA2 differentially regulate RAD51 binding on single- versus double-stranded DNA to stimulate strand exchange

artículo científico publicado en 2009

The T cell receptor triggering apparatus is composed of monovalent or monomeric proteins.

artículo científico publicado en 2011

The changing point-spread function: single-molecule-based super-resolution imaging

artículo científico

The extracellular chaperone clusterin sequesters oligomeric forms of the amyloid-β(1-40) peptide

scientific journal article

The scanned nanopipette: a new tool for high resolution bioimaging and controlled deposition of biomolecules

artículo científico publicado en 2005

The small heat shock protein Hsp27 binds α-synuclein fibrils, preventing elongation and cytotoxicity

artículo científico publicado en 2018

The use of scanning ion conductance microscopy to image A6 cells.

artículo científico publicado en 2004

Three-dimensional RNA structure of the major HIV-1 packaging signal region

artículo científico publicado en 2013

Topographical and electrochemical nanoscale imaging of living cells using voltage-switching mode scanning electrochemical microscopy

artículo científico publicado en 2012

Tracking diffusion of GM1 gangliosides and zona pellucida binding molecules in sperm plasma membranes following cholesterol efflux

artículo científico publicado en 2010

Trapping of proteins under physiological conditions in a nanopipette

artículo científico publicado en 2005

Two-Component Graded Deposition of Biomolecules with a Double-Barreled Nanopipette

artículo científico publicado en 2005

Two-Component Graded Deposition of Biomolecules with a Double-Barreled Nanopipette

article

Two-color fluorescence analysis of individual virions determines the distribution of the copy number of proteins in herpes simplex virus particles

artículo científico publicado en 2007

Two-state model of conformational fluctuation in a DNA hairpin-loop

article

Ubiquitin chain conformation regulates recognition and activity of interacting proteins

artículo científico publicado en 2012

Ultrarapid generation of femtoliter microfluidic droplets for single-molecule-counting immunoassays

artículo científico publicado en 2013

Ultrasensitive Measurement of Ca2+ Influx into Lipid Vesicles Induced by Protein Aggregates

Ultrasensitive Measurement of Ca2+ Influx into Lipid Vesicles Induced by Protein Aggregates.

artículo científico publicado en 2017

Ultrasensitive coincidence fluorescence detection of single DNA molecules

artículo científico publicado en 2003

Use of fluorescence resonance energy transfer to investigate the conformation of DNA substrates bound to the Klenow fragment.

artículo científico publicado en 1998

Vibrational Spectroscopy of Mechanically Compressed Monolayers

article

Virtual-'light-sheet' single-molecule localisation microscopy enables quantitative optical sectioning for super-resolution imaging

artículo científico publicado en 2015

Writing with DNA and Protein Using a Nanopipet for Controlled Delivery

scientific article published on 01 July 2002

“Hearing” Bond Breakage. Measurement of Bond Rupture Forces Using a Quartz Crystal Microbalance

Dominio Público Uruguay está sostenido por:

Acerca de Dominio Público Uruguay

Ayuda