Lista de obras - Colin Watts - Dominio Público Uruguay

3-phosphoinositide-dependent kinase 1 deficiency perturbs Toll-like receptor signaling events and actin cytoskeleton dynamics in dendritic cells.

artículo científico publicado en 2007

A Multifunctional Protease Inhibitor To Regulate Endolysosomal Function ⬇️

artículo científico publicado el 19 de septiembre de 2011

A combination of SILAC and nucleotide acyl phosphate labelling reveals unexpected targets of the Rsk inhibitor BI-D1870.

artículo científico publicado en 2014

A crucial role for β2 integrins in podosome formation, dynamics and Toll-like-receptor-signaled disassembly in dendritic cells

artículo científico publicado en 2014

A role for ARF6 in dendritic cell podosome formation and migration

artículo científico publicado en 2008

An asparaginyl endopeptidase processes a microbial antigen for class II MHC presentation.

artículo científico publicado en 1998

Antibody modulation of antigen presentation: positive and negative effects on presentation of the tetanus toxin antigen via the murine B cell isoform of FcgammaRII.

artículo científico publicado en 2002

Antigen endocytosis and presentation mediated by human membrane IgG1 in the absence of the Ig(alpha)/Ig(beta) dimer

artículo científico publicado en 1997

Antigen processing and class II MHC peptide-loading compartments in human B-lymphoblastoid cells

scientific article published in Nature

Application of a novel highly sensitive activity-based probe for detection of cathepsin G ⬇️

artículo científico publicado el 23 de noviembre de 2011

Asparagine deamidation perturbs antigen presentation on class II major histocompatibility complex molecules

artículo científico publicado en 2005

Asparagine endopeptidase can initiate the removal of the MHC class II invariant chain chaperone.

artículo científico publicado en 2003

Asparagine endopeptidase is required for normal kidney physiology and homeostasis

scientific journal article

Asparaginyl endopeptidase: case history of a class II MHC compartment protease.

artículo científico publicado en 2005

Bm-CPI-2, a cystatin from Brugia malayi nematode parasites, differs from Caenorhabditis elegans cystatins in a specific site mediating inhibition of the antigen-processing enzyme AEP.

artículo científico publicado en 2005

Bm-CPI-2, a cystatin homolog secreted by the filarial parasite Brugia malayi, inhibits class II MHC-restricted antigen processing.

artículo científico publicado en 2001

Capture and processing of exogenous antigens for presentation on MHC molecules.

artículo científico publicado en 1997

Chronic exposure of astrocytes to interferon-α reveals molecular changes related to Aicardi-Goutieres syndrome

artículo científico publicado en 2013

Class I MHC presentation of exogenous soluble antigen via macropinocytosis in bone marrow macrophages.

artículo científico publicado en 1995

Class II MHC: sweetening the peptide only diet?

artículo científico publicado en 2004

Cloning, isolation, and characterization of mammalian legumain, an asparaginyl endopeptidase

artículo científico publicado en 1997

Constitutive macropinocytosis allows TAP-dependent major histocompatibility complex class I presentation of exogenous soluble antigen by bone marrow-derived dendritic cells

artículo científico publicado en 1997

Cystatin F Ensures Eosinophil Survival by Regulating Granule Biogenesis.

artículo científico publicado en 2016

Cystatin F is a cathepsin C-directed protease inhibitor regulated by proteolysis

artículo científico publicado en 2008

Cystatin F regulates proteinase activity in IL-2-activated natural killer cells.

artículo científico publicado en 2014

Cystatin M/E is a high affinity inhibitor of cathepsin V and cathepsin L by a reactive site that is distinct from the legumain-binding site. A novel clue for the role of cystatin M/E in epidermal cornification.

artículo científico publicado en 2006

Dendritic cell podosomes are protrusive and invade the extracellular matrix using metalloproteinase MMP-14.

artículo científico publicado en 2010

Destructive potential of the aspartyl protease cathepsin D in MHC class II-restricted antigen processing.

artículo científico publicado en 2005

Destructive processing by asparagine endopeptidase limits presentation of a dominant T cell epitope in MBP.

artículo científico publicado en 2002

Distinct intracellular compartments involved in invariant chain degradation and antigenic peptide loading of major histocompatibility complex (MHC) class II molecules

artículo científico publicado en 1997

Distinct protease requirements for antigen presentation in vitro and in vivo.

artículo científico publicado en 2010

Disulfide bonds in merozoite surface protein 1 of the malaria parasite impede efficient antigen processing and affect the in vivo antibody response

artículo científico publicado en 2004

Disulfide bonds in merozoite surface protein 1 of the malaria parasite impede efficient antigen processing and affect the in vivo antibody response

artículo científico publicado en 2004

Diverse regulatory roles for lysosomal proteases in the immune response

artículo científico publicado en 2009

Enhanced Dendritic Cell Antigen Capture via Toll-Like Receptor-Induced Actin Remodeling

artículo científico publicado en 2004

Functional early endosomes are required for maturation of major histocompatibility complex class II molecules in human B lymphoblastoid cells.

artículo científico publicado en 1999

Glycosylation directs targeting and activation of cystatin f from intracellular and extracellular sources.

artículo científico publicado en 2009

Immunology Inside the gearbox of the dendritic cell

artículo científico publicado en 1997

Immunology. The bell tolls for phagosome maturation

artículo científico publicado en 2004

Internalization of exogenous cystatin F supresses cysteine proteases and induces the accumulation of single-chain cathepsin L by multiple mechanisms.

artículo científico publicado en 2011

Irreversible association of peptides with class II MHC molecules in living cells.

artículo científico publicado en 1992

Legumain and cathepsin-L expression in human unstable carotid plaque.

artículo científico publicado en 2009

Location, location, location: identifying the neighborhoods of LPS signaling.

artículo científico publicado en 2008

Loss of beta2-integrin-mediated cytoskeletal linkage reprogrammes dendritic cells to a mature migratory phenotype.

artículo científico publicado en 2014

Lysosomal protease deficiency or substrate overload induces an oxidative-stress mediated STAT3-dependent pathway of lysosomal homeostasis

artículo científico publicado en 2018

Macropinocytosis

artículo científico publicado en 1995

Membrane dynamics in endocytosis.

artículo científico publicado en 1996

Membrane ruffling, macropinocytosis and antigen presentation in the absence of gelsolin in murine dendritic cells.

artículo científico publicado en 1999

Modulation by epitope-specific antibodies of class II MHC-restricted presentation of the tetanus toxin antigen

scientific article published on 01 August 1998

Modulation of antigen processing by bound antibodies can boost or suppress class II major histocompatibility complex presentation of different T cell determinants

artículo científico publicado en 1995

Neuroprotective actions of PIKE-L by inhibition of SET proteolytic degradation by asparagine endopeptidase

artículo científico publicado en 2008

Novel cell-permeable acyloxymethylketone inhibitors of asparaginyl endopeptidase.

artículo científico publicado en 2003

Partial separation of a sodium-dependent transport system for amino acids in avian erythrocyte membranes

scientific article published on 01 October 1978

Peptide partners call the tune

artículo científico publicado en 1994

Phagocytosis: How the Phagosome Became the Phag-ER-some

artículo científico publicado en 2002

Phagosome neutrality in host defense

artículo científico publicado en 2006

Production of soluble single-chain T-cell receptor fragments in Escherichia coli trxB mutants ⬇️

artículo científico publicado el 1 de febrero de 1998

Proximal effects of Toll-like receptor activation in dendritic cells

artículo científico publicado en 2006

Rac is required for constitutive macropinocytosis by dendritic cells but does not control its downregulation

artículo científico publicado en 2000

Reconstruction of a pathway of antigen processing and class II MHC peptide capture.

artículo científico publicado en 2007

Regulation of cathepsins S and L by cystatin F during maturation of dendritic cells

artículo científico publicado en 2012

Structural and functional basis for p38-MK2-activated Rsk signaling in toll-like receptor-stimulated dendritic cells.

artículo científico publicado en 2014

Structural basis of reduction-dependent activation of human cystatin F.

artículo científico publicado en 2006

TLR ligand-induced podosome disassembly in dendritic cells is ADAM17 dependent

artículo científico publicado en 2008

TLR signalling regulated antigen presentation in dendritic cells.

artículo científico publicado en 2010

The MAPK-activated kinase Rsk controls an acute Toll-like receptor signaling response in dendritic cells and is activated through two distinct pathways

scientific journal article

The PDK1-Rsk Signaling Pathway Controls Langerhans Cell Proliferation and Patterning

artículo científico publicado en 2015

The endosome-lysosome pathway and information generation in the immune system

artículo científico publicado en 2012

The exogenous pathway for antigen presentation on major histocompatibility complex class II and CD1 molecules

artículo científico publicado en 2004

The spontaneously adhesive leukocyte function-associated antigen-1 (LFA-1) integrin in effector T cells mediates rapid actin- and calmodulin-dependent adhesion strengthening to ligand under shear flow

artículo científico publicado en 2013

The structures of the H(C) fragment of tetanus toxin with carbohydrate subunit complexes provide insight into ganglioside binding

artículo científico publicado en 2000

[13] Analysis of M13 procoat assembly into membranes in vitro

article

Lista de obras de Colin Watts

3-phosphoinositide-dependent kinase 1 deficiency perturbs Toll-like receptor signaling events and actin cytoskeleton dynamics in dendritic cells.

A Multifunctional Protease Inhibitor To Regulate Endolysosomal Function ⬇️

A combination of SILAC and nucleotide acyl phosphate labelling reveals unexpected targets of the Rsk inhibitor BI-D1870.

A crucial role for β2 integrins in podosome formation, dynamics and Toll-like-receptor-signaled disassembly in dendritic cells

A role for ARF6 in dendritic cell podosome formation and migration

An asparaginyl endopeptidase processes a microbial antigen for class II MHC presentation.

Antibody modulation of antigen presentation: positive and negative effects on presentation of the tetanus toxin antigen via the murine B cell isoform of FcgammaRII.

Antigen endocytosis and presentation mediated by human membrane IgG1 in the absence of the Ig(alpha)/Ig(beta) dimer

Antigen processing and class II MHC peptide-loading compartments in human B-lymphoblastoid cells

Application of a novel highly sensitive activity-based probe for detection of cathepsin G ⬇️

Asparagine deamidation perturbs antigen presentation on class II major histocompatibility complex molecules

Asparagine endopeptidase can initiate the removal of the MHC class II invariant chain chaperone.

Asparagine endopeptidase is required for normal kidney physiology and homeostasis

Asparaginyl endopeptidase: case history of a class II MHC compartment protease.

Bm-CPI-2, a cystatin from Brugia malayi nematode parasites, differs from Caenorhabditis elegans cystatins in a specific site mediating inhibition of the antigen-processing enzyme AEP.

Bm-CPI-2, a cystatin homolog secreted by the filarial parasite Brugia malayi, inhibits class II MHC-restricted antigen processing.

Capture and processing of exogenous antigens for presentation on MHC molecules.

Chronic exposure of astrocytes to interferon-α reveals molecular changes related to Aicardi-Goutieres syndrome

Class I MHC presentation of exogenous soluble antigen via macropinocytosis in bone marrow macrophages.

Class II MHC: sweetening the peptide only diet?

Cloning, isolation, and characterization of mammalian legumain, an asparaginyl endopeptidase

Constitutive macropinocytosis allows TAP-dependent major histocompatibility complex class I presentation of exogenous soluble antigen by bone marrow-derived dendritic cells

Cystatin F Ensures Eosinophil Survival by Regulating Granule Biogenesis.

Cystatin F is a cathepsin C-directed protease inhibitor regulated by proteolysis

Cystatin F regulates proteinase activity in IL-2-activated natural killer cells.

Cystatin M/E is a high affinity inhibitor of cathepsin V and cathepsin L by a reactive site that is distinct from the legumain-binding site. A novel clue for the role of cystatin M/E in epidermal cornification.

Dendritic cell podosomes are protrusive and invade the extracellular matrix using metalloproteinase MMP-14.

Destructive potential of the aspartyl protease cathepsin D in MHC class II-restricted antigen processing.

Destructive processing by asparagine endopeptidase limits presentation of a dominant T cell epitope in MBP.

Distinct intracellular compartments involved in invariant chain degradation and antigenic peptide loading of major histocompatibility complex (MHC) class II molecules

Distinct protease requirements for antigen presentation in vitro and in vivo.

Disulfide bonds in merozoite surface protein 1 of the malaria parasite impede efficient antigen processing and affect the in vivo antibody response

Disulfide bonds in merozoite surface protein 1 of the malaria parasite impede efficient antigen processing and affect the in vivo antibody response

Diverse regulatory roles for lysosomal proteases in the immune response

Enhanced Dendritic Cell Antigen Capture via Toll-Like Receptor-Induced Actin Remodeling

Functional early endosomes are required for maturation of major histocompatibility complex class II molecules in human B lymphoblastoid cells.

Glycosylation directs targeting and activation of cystatin f from intracellular and extracellular sources.

Immunology Inside the gearbox of the dendritic cell

Immunology. The bell tolls for phagosome maturation

Internalization of exogenous cystatin F supresses cysteine proteases and induces the accumulation of single-chain cathepsin L by multiple mechanisms.

Irreversible association of peptides with class II MHC molecules in living cells.

Legumain and cathepsin-L expression in human unstable carotid plaque.

Location, location, location: identifying the neighborhoods of LPS signaling.

Loss of beta2-integrin-mediated cytoskeletal linkage reprogrammes dendritic cells to a mature migratory phenotype.

Lysosomal protease deficiency or substrate overload induces an oxidative-stress mediated STAT3-dependent pathway of lysosomal homeostasis

Macropinocytosis

Membrane dynamics in endocytosis.

Membrane ruffling, macropinocytosis and antigen presentation in the absence of gelsolin in murine dendritic cells.

Modulation by epitope-specific antibodies of class II MHC-restricted presentation of the tetanus toxin antigen

Modulation of antigen processing by bound antibodies can boost or suppress class II major histocompatibility complex presentation of different T cell determinants

Neuroprotective actions of PIKE-L by inhibition of SET proteolytic degradation by asparagine endopeptidase

Novel cell-permeable acyloxymethylketone inhibitors of asparaginyl endopeptidase.

Partial separation of a sodium-dependent transport system for amino acids in avian erythrocyte membranes

Peptide partners call the tune

Phagocytosis: How the Phagosome Became the Phag-ER-some

Phagosome neutrality in host defense

Production of soluble single-chain T-cell receptor fragments in Escherichia coli trxB mutants ⬇️

Proximal effects of Toll-like receptor activation in dendritic cells

Rac is required for constitutive macropinocytosis by dendritic cells but does not control its downregulation

Reconstruction of a pathway of antigen processing and class II MHC peptide capture.

Regulation of cathepsins S and L by cystatin F during maturation of dendritic cells

Structural and functional basis for p38-MK2-activated Rsk signaling in toll-like receptor-stimulated dendritic cells.

Structural basis of reduction-dependent activation of human cystatin F.

TLR ligand-induced podosome disassembly in dendritic cells is ADAM17 dependent

TLR signalling regulated antigen presentation in dendritic cells.

The MAPK-activated kinase Rsk controls an acute Toll-like receptor signaling response in dendritic cells and is activated through two distinct pathways

The PDK1-Rsk Signaling Pathway Controls Langerhans Cell Proliferation and Patterning

The endosome-lysosome pathway and information generation in the immune system

The exogenous pathway for antigen presentation on major histocompatibility complex class II and CD1 molecules

The spontaneously adhesive leukocyte function-associated antigen-1 (LFA-1) integrin in effector T cells mediates rapid actin- and calmodulin-dependent adhesion strengthening to ligand under shear flow

The structures of the H(C) fragment of tetanus toxin with carbohydrate subunit complexes provide insight into ganglioside binding

[13] Analysis of M13 procoat assembly into membranes in vitro