Lista de obras - Jesper Qualmann Svejstrup

A RECQ5-RNA polymerase II association identified by targeted proteomic analysis of human chromatin

artículo científico publicado en 2008

A Rad26-Def1 complex coordinates repair and RNA pol II proteolysis in response to DNA damage

artículo científico publicado en 2002

A Ubiquitin-Binding Domain that Binds a Structural Fold Distinct from that of Ubiquitin

scientific article published on 13 June 2019

A role for checkpoint kinase-dependent Rad26 phosphorylation in transcription-coupled DNA repair in Saccharomyces cerevisiae.

artículo científico publicado en 2009

A role for noncoding transcription in activation of the yeast PHO5 gene

artículo científico publicado en 2007

A ubiquitin-binding domain in Cockayne syndrome B required for transcription-coupled nucleotide excision repair

artículo científico publicado en 2010

A ubiquitylation site in Cockayne syndrome B required for repair of oxidative DNA damage, but not for transcription-coupled nucleotide excision repair

artículo científico publicado en 2016

An Assay for Studying Ubiquitylation of RNA Polymerase II and Other Proteins in Crude Yeast Extracts

artículo científico publicado en 2006

An iron-sulfur cluster domain in Elp3 important for the structural integrity of elongator

artículo científico publicado en 2008

An rtt109-independent role for vps75 in transcription-associated nucleosome dynamics

artículo científico publicado en 2009

Analysis of RNA polymerase II ubiquitylation and proteasomal degradation

scientific article published on 13 February 2019

Annotation matters: validating the discovery of cancer drivers

scientific article published on 31 August 2020

CDK13 cooperates with CDK12 to control global RNA polymerase II processivity

artículo científico publicado en 2020

Camptothecin inhibits both the cleavage and religation reactions of eukaryotic DNA topoisomerase I

artículo científico publicado en 1992

Causes and consequences of RNA polymerase II stalling during transcript elongation

artículo científico publicado en 2020

Characterization of an altered DNA catalysis of a camptothecin-resistant eukaryotic topoisomerase I.

artículo científico publicado en 1993

Chromatin elongation factors

artículo científico publicado en 2002

Cockayne syndrome B protein regulates recruitment of the Elongin A ubiquitin ligase to sites of DNA damage.

artículo científico publicado en 2017

Communication between Distant Sites in RNA Polymerase II through Ubiquitylation Factors and the Polymerase CTD

article by Baggavalli P. Somesh et al published April 2007 in Cell

Contending with transcriptional arrest during RNAPII transcript elongation

artículo científico publicado en 2007

Correction: Retention of the Native Epigenome in Purified Mammalian Chromatin

artículo científico publicado en 2015

DBIRD complex integrates alternative mRNA splicing with RNA polymerase II transcript elongation

artículo científico publicado en 2012

DERP6 (ELP5) and C3ORF75 (ELP6) regulate tumorigenicity and migration of melanoma cells as subunits of Elongator

artículo científico publicado en 2012

DNA damage-induced Def1-RNA polymerase II interaction and Def1 requirement for polymerase ubiquitylation in vitro

artículo científico publicado en 2004

Damage-induced ubiquitylation of human RNA polymerase II by the ubiquitin ligase Nedd4, but not Cockayne syndrome proteins or BRCA1

artículo científico publicado en 2007

Different forms of TFIIH for transcription and DNA repair: holo-TFIIH and a nucleotide excision repairosome

artículo científico publicado en 1995

Direct inhibition of RNA polymerase II transcription by RECQL5.

artículo científico publicado en 2009

Distinct ubiquitin ligases act sequentially for RNA polymerase II polyubiquitylation

artículo científico publicado en 2009

Dual roles of a multiprotein complex from S. cerevisiae in transcription and DNA repair

artículo científico

Dysregulation of gene expression as a cause of Cockayne syndrome neurological disease

artículo científico publicado en 2014

Elongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome Stability

artículo científico publicado en 2019

Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability

scientific article published on 09 June 2021

Elongator complex: how many roles does it play?

artículo científico publicado en 2007

Elongator interactions with nascent mRNA revealed by RNA immunoprecipitation

artículo científico publicado en 2004

Elongator is a histone H3 and H4 acetyltransferase important for normal histone acetylation levels in vivo

artículo científico publicado en 2002

Elongator, a Multisubunit Component of a Novel RNA Polymerase II Holoenzyme for Transcriptional Elongation

artículo científico publicado en 1999

Evidence for a mediator cycle at the initiation of transcription.

artículo científico publicado en 1997

Evidence for distinct mechanisms facilitating transcript elongation through chromatin in vivo

artículo científico publicado en 2004

Evidence that transcript cleavage is essential for RNA polymerase II transcription and cell viability

artículo científico publicado en 2010

GTP-dependent binding and nuclear transport of RNA polymerase II by Npa3 protein

artículo científico publicado en 2011

Genome-wide reconstitution of chromatin transactions reveals that RSC preferentially disrupts H2AZ-containing nucleosomes

artículo científico publicado en 2019

Heat shock induces premature transcript termination and reconfigures the human transcriptome

artículo científico publicado en 2022

Hereditary dysautonomias: current knowledge and collaborations for the future.

artículo científico publicado en 2003

Hyperphosphorylation of the C-terminal repeat domain of RNA polymerase II facilitates dissociation of its complex with mediator

artículo científico publicado en 2007

In vitro reconstitution of PHO5 promoter chromatin remodeling points to a role for activator-nucleosome competition in vivo

artículo científico publicado en 2010

Incision of a 1,3-intrastrand d(GpTpG)-cisplatin adduct by nucleotide excision repair proteins from yeast

artículo científico publicado en 2002

Increasing the rate of chromatin remodeling and gene activation--a novel role for the histone acetyltransferase Gcn5

artículo científico publicado en 2001

Interacting partners of the Tfb2 subunit from yeast TFIIH.

artículo científico publicado en 2010

Interaction of Fcp1 phosphatase with elongating RNA polymerase II holoenzyme, enzymatic mechanism of action, and genetic interaction with elongator

artículo científico publicado en 2004

Involvement of yeast carboxy-terminal domain kinase I (CTDK-I) in transcription elongation in vivo

artículo científico publicado en 2001

Isolation and mass spectrometry of transcription factor complexes

artículo científico publicado en 2002

Keeping RNA and DNA Apart during Transcription ⬇️

artículo científico publicado el 1 de septiembre de 2003

Mechanisms of transcription-coupled DNA repair

artículo científico publicado en 2002

Mechanistic interpretation of promoter-proximal peaks and RNAPII density maps

artículo científico publicado en 2013

Minimal DNA duplex requirements for topoisomerase I-mediated cleavage in vitro

scientific article published in Journal of Biological Chemistry

Minimal DNA requirement for topoisomerase II-mediated cleavage in vitro

artículo científico publicado en 1990

Molecular architecture, structure-function relationship, and importance of the Elp3 subunit for the RNA binding of holo-elongator

artículo científico publicado en 2004

MultiDsk: a ubiquitin-specific affinity resin

artículo científico publicado en 2012

Multiomic Analysis of the UV-Induced DNA Damage Response ⬇️

artículo científico publicado en 2016

Multiple mechanisms confining RNA polymerase II ubiquitylation to polymerases undergoing transcriptional arrest

artículo científico publicado en 2005

Mutation of cancer driver MLL2 results in transcription stress and genome instability.

artículo científico

New technique for uncoupling the cleavage and religation reactions of eukaryotic topoisomerase I. The mode of action of camptothecin at a specific recognition site

artículo científico publicado en 1991

Nucleotide excision repair in the yeast Saccharomyces cerevisiae: its relationship to specialized mitotic recombination and RNA polymerase II basal transcription

artículo científico publicado en 1995

Overlapping roles for the histone acetyltransferase activities of SAGA and elongator in vivo

artículo científico publicado en 2000

Pharmacological Bypass of Cockayne Syndrome B Function in Neuronal Differentiation

artículo científico publicado en 2016

Physical and functional interaction between Elongator and the chromatin-associated Kti12 protein

artículo científico publicado en 2005

Proteasome-mediated processing of Def1, a critical step in the cellular response to transcription stress

artículo científico publicado en 2013

Purification and characterization of human topoisomerase I mutants

artículo científico publicado en 1996

Purification and characterization of the human elongator complex

artículo científico publicado en 2002

Purification of Elongating RNA Polymerase II and Other Factors from Yeast Chromatin

scientific article published on 01 January 2003

RECQL5 controls transcript elongation and suppresses genome instability associated with transcription stress

artículo científico publicado en 2014

RECQL5 helicase: connections to DNA recombination and RNA polymerase II transcription

artículo científico publicado en 2010

RNA Immunoprecipitation to Determine RNA-Protein Associations In Vivo

scientific article published on 01 June 2009

RNA immunoprecipitation for determining RNA-protein associations in vivo

scientific article published on August 2006

RNA polymerase II Transcript Elongation ⬇️

artículo científico publicado el 1 de enero de 2013

RNA polymerase II collision interrupts convergent transcription

artículo científico publicado en 2012

RNA polymerase II: a "nobel" enzyme demystified

artículo científico publicado en 2006

RNA polymerase transcription factor IIH holoenzyme from yeast.

artículo científico publicado en 1994

Recent insights on DNA repair. The mechanism of damaged nucleotide excision in eukaryotes and its relationship to other cellular processes

artículo científico publicado en 1994

Relationship of CDK-activating kinase and RNA polymerase II CTD kinase TFIIH/TFIIK

artículo científico publicado en 1994

Reprogramming chromatin

artículo científico publicado en 2012

Rescue of arrested RNA polymerase II complexes

artículo científico publicado en 2003

Retention of the Native Epigenome in Purified Mammalian Chromatin

artículo científico publicado en 2015

Reversal of RNA polymerase II ubiquitylation by the ubiquitin protease Ubp3.

artículo científico publicado en 2008

Role of elongator subunit Elp3 in Drosophila melanogaster larval development and immunity.

artículo científico publicado en 2011

SCAF4 and SCAF8, mRNA Anti-Terminator Proteins

scientific article published on 16 May 2019

Spreading of Sir3 protein in cells with severe histone H3 hypoacetylation

artículo científico publicado en 2003

Stability, flexibility, and dynamic interactions of colliding RNA polymerase II elongation complexes

artículo científico publicado en 2009

Studies of the topoisomerase II-mediated cleavage and religation reactions by use of a suicidal double-stranded DNA substrate ⬇️

artículo científico publicado el 15 de mayo de 1991

Studying RNA–Protein Interactions In Vivo By RNA Immunoprecipitation

Subunits of yeast RNA polymerase II transcription factor TFIIH encoded by the CCL1 gene.

artículo científico publicado en 1996

Synovial Sarcoma Mechanisms: A Series of Unfortunate Events ⬇️

artículo científico publicado el 28 de marzo de 2013

The Cellular Response to Transcription-Blocking DNA Damage.

artículo científico publicado en 2018

The DNA binding, cleavage, and religation reactions of eukaryotic topoisomerases I and II.

artículo científico publicado en 1994

The Elp2 Subunit of Elongator and Elongating RNA Polymerase II Holoenzyme Is a WD40 Repeat Protein

artículo científico publicado en 2000

The NC2 alpha and beta subunits play different roles in vivo

artículo científico publicado en 2002

The RAD7, RAD16, and RAD23 genes of Saccharomyces cerevisiae: requirement for transcription-independent nucleotide excision repair in vitro and interactions between the gene products

artículo científico publicado en 1997

The RNA polymerase II transcription cycle: cycling through chromatin

artículo científico publicado en 2004

The interface between transcription and mechanisms maintaining genome integrity

scientific article published on March 2010

The yeast TFB1 and SSL1 genes, which encode subunits of transcription factor IIH, are required for nucleotide excision repair and RNA polymerase II transcription

artículo científico publicado en 1995

Transcript Elongation by RNA Polymerase II.

artículo científico publicado en 2010

Transcription Repair Coupling Factor

artículo científico publicado en 2002

Transcription factor b (TFIIH) is required during nucleotide-excision repair in yeast

scientific article published in Nature

Transcription impairment and cell migration defects in elongator-depleted cells: implication for familial dysautonomia

artículo científico publicado en 2006

Transcription. Histones face the FACT.

artículo científico publicado en 2003

Transcription: another mark in the tail ⬇️

artículo científico publicado el 22 de mayo de 2012

Transcriptional inhibition of genes with severe histone h3 hypoacetylation in the coding region

artículo científico publicado en 2002

Translation stress and collided ribosomes are co-activators of cGAS

artículo científico publicado en 2021

Triptolide is an inhibitor of RNA polymerase I and II-dependent transcription leading predominantly to down-regulation of short-lived mRNA.

artículo científico

UV Irradiation Induces a Non-coding RNA that Functionally Opposes the Protein Encoded by the Same Gene

artículo científico publicado en 2017

Ubiquitylation and degradation of elongating RNA polymerase II: the last resort

artículo científico

Using TTchem-seq for profiling nascent transcription and measuring transcript elongation

artículo científico publicado en 2020

Vps75, a new yeast member of the NAP histone chaperone family

artículo científico publicado en 2007

Yeast nucleotide excision repair proteins Rad2 and Rad4 interact with RNA polymerase II basal transcription factor b (TFIIH)

artículo científico

Lista de obras de Jesper Qualmann Svejstrup

A RECQ5-RNA polymerase II association identified by targeted proteomic analysis of human chromatin

A Rad26-Def1 complex coordinates repair and RNA pol II proteolysis in response to DNA damage

A Ubiquitin-Binding Domain that Binds a Structural Fold Distinct from that of Ubiquitin

A role for checkpoint kinase-dependent Rad26 phosphorylation in transcription-coupled DNA repair in Saccharomyces cerevisiae.

A role for noncoding transcription in activation of the yeast PHO5 gene

A ubiquitin-binding domain in Cockayne syndrome B required for transcription-coupled nucleotide excision repair

A ubiquitylation site in Cockayne syndrome B required for repair of oxidative DNA damage, but not for transcription-coupled nucleotide excision repair

An Assay for Studying Ubiquitylation of RNA Polymerase II and Other Proteins in Crude Yeast Extracts

An iron-sulfur cluster domain in Elp3 important for the structural integrity of elongator

An rtt109-independent role for vps75 in transcription-associated nucleosome dynamics

Analysis of RNA polymerase II ubiquitylation and proteasomal degradation

Annotation matters: validating the discovery of cancer drivers

CDK13 cooperates with CDK12 to control global RNA polymerase II processivity

Camptothecin inhibits both the cleavage and religation reactions of eukaryotic DNA topoisomerase I

Causes and consequences of RNA polymerase II stalling during transcript elongation

Characterization of an altered DNA catalysis of a camptothecin-resistant eukaryotic topoisomerase I.

Chromatin elongation factors

Cockayne syndrome B protein regulates recruitment of the Elongin A ubiquitin ligase to sites of DNA damage.

Communication between Distant Sites in RNA Polymerase II through Ubiquitylation Factors and the Polymerase CTD

Contending with transcriptional arrest during RNAPII transcript elongation

Correction: Retention of the Native Epigenome in Purified Mammalian Chromatin

DBIRD complex integrates alternative mRNA splicing with RNA polymerase II transcript elongation

DERP6 (ELP5) and C3ORF75 (ELP6) regulate tumorigenicity and migration of melanoma cells as subunits of Elongator

DNA damage-induced Def1-RNA polymerase II interaction and Def1 requirement for polymerase ubiquitylation in vitro

Damage-induced ubiquitylation of human RNA polymerase II by the ubiquitin ligase Nedd4, but not Cockayne syndrome proteins or BRCA1

Different forms of TFIIH for transcription and DNA repair: holo-TFIIH and a nucleotide excision repairosome

Direct inhibition of RNA polymerase II transcription by RECQL5.

Distinct ubiquitin ligases act sequentially for RNA polymerase II polyubiquitylation

Dual roles of a multiprotein complex from S. cerevisiae in transcription and DNA repair

Dysregulation of gene expression as a cause of Cockayne syndrome neurological disease

Elongation Factor TFIIS Prevents Transcription Stress and R-Loop Accumulation to Maintain Genome Stability

Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability

Elongator complex: how many roles does it play?

Elongator interactions with nascent mRNA revealed by RNA immunoprecipitation

Elongator is a histone H3 and H4 acetyltransferase important for normal histone acetylation levels in vivo

Elongator, a Multisubunit Component of a Novel RNA Polymerase II Holoenzyme for Transcriptional Elongation

Evidence for a mediator cycle at the initiation of transcription.

Evidence for distinct mechanisms facilitating transcript elongation through chromatin in vivo

Evidence that transcript cleavage is essential for RNA polymerase II transcription and cell viability

GTP-dependent binding and nuclear transport of RNA polymerase II by Npa3 protein

Genome-wide reconstitution of chromatin transactions reveals that RSC preferentially disrupts H2AZ-containing nucleosomes

Heat shock induces premature transcript termination and reconfigures the human transcriptome

Hereditary dysautonomias: current knowledge and collaborations for the future.

Hyperphosphorylation of the C-terminal repeat domain of RNA polymerase II facilitates dissociation of its complex with mediator

In vitro reconstitution of PHO5 promoter chromatin remodeling points to a role for activator-nucleosome competition in vivo

Incision of a 1,3-intrastrand d(GpTpG)-cisplatin adduct by nucleotide excision repair proteins from yeast

Increasing the rate of chromatin remodeling and gene activation--a novel role for the histone acetyltransferase Gcn5

Interacting partners of the Tfb2 subunit from yeast TFIIH.

Interaction of Fcp1 phosphatase with elongating RNA polymerase II holoenzyme, enzymatic mechanism of action, and genetic interaction with elongator

Involvement of yeast carboxy-terminal domain kinase I (CTDK-I) in transcription elongation in vivo

Isolation and mass spectrometry of transcription factor complexes

Keeping RNA and DNA Apart during Transcription ⬇️

Mechanisms of transcription-coupled DNA repair

Mechanistic interpretation of promoter-proximal peaks and RNAPII density maps

Minimal DNA duplex requirements for topoisomerase I-mediated cleavage in vitro

Minimal DNA requirement for topoisomerase II-mediated cleavage in vitro

Molecular architecture, structure-function relationship, and importance of the Elp3 subunit for the RNA binding of holo-elongator

MultiDsk: a ubiquitin-specific affinity resin

Multiomic Analysis of the UV-Induced DNA Damage Response ⬇️

Multiple mechanisms confining RNA polymerase II ubiquitylation to polymerases undergoing transcriptional arrest

Mutation of cancer driver MLL2 results in transcription stress and genome instability.

New technique for uncoupling the cleavage and religation reactions of eukaryotic topoisomerase I. The mode of action of camptothecin at a specific recognition site

Nucleotide excision repair in the yeast Saccharomyces cerevisiae: its relationship to specialized mitotic recombination and RNA polymerase II basal transcription

Overlapping roles for the histone acetyltransferase activities of SAGA and elongator in vivo

Pharmacological Bypass of Cockayne Syndrome B Function in Neuronal Differentiation

Physical and functional interaction between Elongator and the chromatin-associated Kti12 protein

Proteasome-mediated processing of Def1, a critical step in the cellular response to transcription stress

Purification and characterization of human topoisomerase I mutants

Purification and characterization of the human elongator complex

Purification of Elongating RNA Polymerase II and Other Factors from Yeast Chromatin

RECQL5 controls transcript elongation and suppresses genome instability associated with transcription stress

RECQL5 helicase: connections to DNA recombination and RNA polymerase II transcription

RNA Immunoprecipitation to Determine RNA-Protein Associations In Vivo

RNA immunoprecipitation for determining RNA-protein associations in vivo

RNA polymerase II Transcript Elongation ⬇️

RNA polymerase II collision interrupts convergent transcription

RNA polymerase II: a "nobel" enzyme demystified

RNA polymerase transcription factor IIH holoenzyme from yeast.

Recent insights on DNA repair. The mechanism of damaged nucleotide excision in eukaryotes and its relationship to other cellular processes