Lista de obras - Gabriella Campadelli-Fiume

A Heptad Repeat in Herpes Simplex Virus 1 gH, Located Downstream of the α-Helix with Attributes of a Fusion Peptide, Is Critical for Virus Entry and Fusion.

artículo científico publicado en 2007

A Strategy for Cultivation of Retargeted Oncolytic Herpes Simplex Viruses in Non-cancer Cells

artículo científico publicado en 2017

A fully-virulent retargeted oncolytic HSV armed with IL-12 elicits local immunity and vaccine therapy towards distant tumors

artículo científico publicado en 2018

A heptad repeat in herpes simplex virus 1 gH, located downstream of the alpha-helix with attributes of a fusion peptide, is critical for virus entry and fusion

artículo científico publicado en 2005

A herpes simplex virus recombinant that exhibits a single-chain antibody to HER2/neu enters cells through the mammary tumor receptor, independently of the gD receptors

artículo científico publicado en 2006

Absence of human herpesvirus 6 and 7 from spinal fluid and serum of multiple sclerosis patients

scientific article published on 01 October 1999

Alphaherpes viral genes and their functions

Anti-idiotypic antibodies mimicking glycoprotein D of herpes simplex virus identify a cellular protein required for virus spread from cell to cell and virus-induced polykaryocytosis

scientific article published on March 1996

CD68+ cells of monocyte/macrophage lineage in the environment of AIDS-associated and classic-sporadic Kaposi sarcoma are singly or doubly infected with human herpesviruses 7 and 6B.

artículo científico publicado en 1997

Cell-to-cell spread of wild-type herpes simplex virus type 1, but not of syncytial strains, is mediated by the immunoglobulin-like receptors that mediate virion entry, nectin1 (PRR1/HveC/HIgR) and nectin2 (PRR2/HveB)

artículo científico publicado en 2000

Characterization of human herpesvirus-6(U1102) and (GS) gp112 and identification of the Z29-specified homolog

artículo científico publicado en 1992

Chimeric nectin1-poliovirus receptor molecules identify a nectin1 region functional in herpes simplex virus entry

artículo científico publicado en 2001

Coexpression of UL20p and gK inhibits cell-cell fusion mediated by herpes simplex virus glycoproteins gD, gH-gL, and wild-type gB or an endocytosis-defective gB mutant and downmodulates their cell surface expression

artículo científico publicado en 2004

Comparison of murine and human nectin1 binding to herpes simplex virus glycoprotein D (gD) reveals a weak interaction of murine nectin1 to gD and a gD-dependent pathway of entry.

artículo científico publicado en 2001

Complexes between herpes simplex virus glycoproteins gD, gB, and gH detected in cells by complementation of split enhanced green fluorescent protein

artículo científico publicado en 2007

Conservation of the architecture of the Golgi apparatus related to a differential organization of microtubules in polykaryocytes induced by syn- mutants of herpes simplex virus 1.

artículo científico publicado en 1998

Construction of a fully retargeted herpes simplex virus 1 recombinant capable of entering cells solely via human epidermal growth factor receptor 2.

artículo científico publicado en 2008

Critical residues in the CC' ridge of the human nectin1 receptor V domain enable herpes simplex virus entry into the cell and act synergistically with the downstream region

artículo científico publicado en 2002

Cross talk among the glycoproteins involved in herpes simplex virus entry and fusion: the interaction between gB and gH/gL does not necessarily require gD.

artículo científico publicado en 2009

Development of recombinant diagnostic reagents based on pp85(U14) and p86(U11) proteins to detect the human immune response to human herpesvirus 7 infection.

artículo científico publicado en 1999

Dissociation of HSV gL from gH by αvβ6- or αvβ8-integrin promotes gH activation and virus entry

artículo científico publicado en 2015

Dual Ligand Insertion in gB and gD of Oncolytic Herpes Simplex Viruses for Retargeting to a Producer Vero Cell Line and to Cancer Cells

artículo científico publicado en 2017

Entry of alphaherpesviruses into the cell

Entry of herpes simplex virus mediated by chimeric forms of nectin1 retargeted to endosomes or to lipid rafts occurs through acidic endosomes

artículo científico publicado en 2004

Eradication of glioblastoma by immuno-virotherapy with a retargeted oncolytic HSV in a preclinical model

scientific article published on 12 February 2019

Glycoprotein C-dependent attachment of herpes simplex virus to susceptible cells leading to productive infection

artículo científico publicado en 1990

Glycoprotein D of bovine herpesvirus 5 (BoHV-5) confers an extended host range to BoHV-1 but does not contribute to invasion of the brain

artículo científico publicado en 2010

Glycoprotein D of herpes simplex virus encodes a domain which precludes penetration of cells expressing the glycoprotein by superinfecting herpes simplex virus

artículo científico publicado en 1990

Glycoprotein D or J delivered in trans blocks apoptosis in SK-N-SH cells induced by a herpes simplex virus 1 mutant lacking intact genes expressing both glycoproteins

artículo científico publicado en 2000

HSV as A Platform for the Generation of Retargeted, Armed, and Reporter-Expressing Oncolytic Viruses

scholarly article by Laura Menotti published in June 2018

Heptad Repeat 2 in Herpes Simplex Virus 1 gH Interacts with Heptad Repeat 1 and Is Critical for Virus Entry and Fusion.

artículo científico publicado en 2007

Heptad repeat 2 in herpes simplex virus 1 gH interacts with heptad repeat 1 and is critical for virus entry and fusion

artículo científico publicado en 2006

Herpes simplex virus envelopment and maturation studied by fracture label.

artículo científico publicado en 1992

Herpes simplex virus gD forms distinct complexes with fusion executors gB and gH/gL in part through the C-terminal profusion domain

artículo científico publicado en 2009

Herpes simplex virus glycoprotein K, but not its syncytial allele, inhibits cell-cell fusion mediated by the four fusogenic glycoproteins, gD, gB, gH, and gL.

artículo científico publicado en 2003

Herpes simplex virus glycoproteins H/L bind to cells independently of {alpha}V{beta}3 integrin and inhibit virus entry, and their constitutive expression restricts infection

artículo científico publicado en 2010

Herpes simplex virus glycoproteins gH/gL and gB bind Toll-like receptor 2, and soluble gH/gL is sufficient to activate NF-κB

artículo científico publicado en 2012

Human herpesvirus 6 envelope glycoproteins B and H-L complex are undetectable on the plasma membrane of infected lymphocytes

artículo científico publicado en 1994

Human herpesvirus 6: An emerging pathogen.

artículo científico publicado en 1999

Human herpesvirus-6 glycoprotein H and L homologs are components of the gp100 complex and the gH external domain is the target for neutralizing monoclonal antibodies

artículo científico publicado en 1993

Human nectin3/PRR3: a novel member of the PVR/PRR/nectin family that interacts with afadin

artículo científico publicado en 2000

Hydrophobic alpha-helices 1 and 2 of herpes simplex virus gH interact with lipids, and their mimetic peptides enhance virus infection and fusion

artículo científico publicado en 2006

Hydrophobic α-Helices 1 and 2 of Herpes Simplex Virus gH Interact with Lipids, and Their Mimetic Peptides Enhance Virus Infection and Fusion.

artículo científico publicado en 2007

Identification of an 85 kDa phosphoprotein as an immunodominant protein specific for human herpesvirus 7-infected cells

scientific article published on 01 March 1996

Increased expression of human herpesvirus 7 in lymphoid organs of AIDS patients

artículo científico publicado en 2000

Inhibition of human tumor growth in mice by an oncolytic herpes simplex virus designed to target solely HER-2-positive cells

scholarly article

Insertion of a ligand to HER2 in gB retargets HSV tropism and obviates the need for activation of the other entry glycoproteins.

artículo científico publicado en 2017

Integrins as Herpesvirus Receptors and Mediators of the Host Signalosome.

artículo científico publicado en 2016

Intermediate forms of glycoconjugates are present in the envelope of herpes simplex virions during their transport along the exocytic pathway

artículo científico publicado en 1995

Intracellular trafficking and maturation of herpes simplex virus type 1 gB and virus egress require functional biogenesis of multivesicular bodies

artículo científico publicado en 2007

Is pityriasis rosea skin healthier than healthy skin?

artículo científico publicado en 2000

Localization and putative function of the UL20 membrane protein in cells infected with herpes simplex virus 1.

artículo científico publicado en 1994

Mapping of herpes simplex virus 1 genes with mutations which overcome host restrictions to infection

artículo científico publicado en 1994

Monoclonal antibodies to glycoprotein B differentiate human herpesvirus 6 into two clusters, variants A and B.

artículo científico publicado en 1993

Monoclonal antibodies to gp100 inhibit penetration of human herpesvirus 6 and polykaryocyte formation in susceptible cells

artículo científico publicado en 1991

Nectin2alpha (PRR2alpha or HveB) and nectin2delta are low-efficiency mediators for entry of herpes simplex virus mutants carrying the Leu25Pro substitution in glycoprotein D

artículo científico publicado en 2000

Novel, soluble isoform of the herpes simplex virus (HSV) receptor nectin1 (or PRR1-HIgR-HveC) modulates positively and negatively susceptibility to HSV infection

artículo científico publicado en 2001

Oncolytic herpes virus retargeted to HER-2.

artículo científico publicado en 2009

Origin of unenveloped capsids in the cytoplasm of cells infected with herpes simplex virus 1

artículo científico publicado en 1991

Persistence of human herpesvirus 7 in normal tissues detected by expression of a structural antigen

artículo científico publicado en 1998

Pityriasis rosea is not associated with human herpesvirus 7.

artículo científico publicado en 1999

Polyvalent and monoclonal antibodies identify major immunogenic proteins specific for human herpesvirus 7-infected cells and have weak cross-reactivity with human herpesvirus 6

artículo científico publicado en 1994

Preclinical therapy of disseminated HER-2⁺ ovarian and breast carcinomas with a HER-2-retargeted oncolytic herpesvirus.

artículo científico publicado en 2013

Prominent role of the Ig-like V domain in trans-interactions of nectins. Nectin3 and nectin 4 bind to the predicted C-C'-C"-D beta-strands of the nectin1 V domain

artículo científico publicado en 2002

Redistribution of microtubules and Golgi apparatus in herpes simplex virus-infected cells and their role in viral exocytosis.

artículo científico publicado en 1995

Replication-competent herpes simplex virus retargeted to HER2 as therapy for high-grade glioma

artículo científico publicado en 2012

Replicative conditioning of Herpes simplex type 1 virus by Survivin promoter, combined to ERBB2 retargeting, improves tumour cell-restricted oncolysis

artículo científico publicado en 2020

Rescue, Purification, and Characterization of a Recombinant HSV Expressing a Transgenic Protein

artículo científico publicado en 2020

Retargeted and Multi-cytokine-Armed Herpes Virus Is a Potent Cancer Endovaccine for Local and Systemic Anti-tumor Treatment

scientific article published on 14 October 2020

Retargeting Strategies for Oncolytic Herpes Simplex Viruses

artículo científico publicado en 2016

Rethinking herpes simplex virus: the way to oncolytic agents

artículo científico publicado en 2011

Selection of a monoclonal antibody specific for variant B human herpesvirus 6-infected mononuclear cells

artículo científico publicado en 1995

Simultaneous Insertion of Two Ligands in gD for Cultivation of Oncolytic Herpes Simplex Viruses in Noncancer Cells and Retargeting to Cancer Receptors

artículo científico publicado en 2017

Spotlight on… Gabriella Campadelli-Fiume.

artículo científico publicado en 2018

Substitution in the murine nectin1 receptor of a single conserved amino acid at a position distal from the herpes simplex virus gD binding site confers high-affinity binding to gD.

artículo científico publicado en 2002

Systemic delivery of HER2-retargeted oncolytic-HSV by mesenchymal stromal cells protects from lung and brain metastases

artículo científico publicado en 2015

The 85-kilodalton phosphoprotein (pp85) of human herpesvirus 7 is encoded by open reading frame U14 and localizes to a tegument substructure in virion particles.

artículo científico publicado en 1997

The Ectodomain of Herpes Simplex Virus Glycoprotein H Contains a Membrane α-Helix with Attributes of an Internal Fusion Peptide, Positionally Conserved in the Herpesviridae Family.

artículo científico publicado en 2007

The Engineering of a Novel Ligand in gH Confers to HSV an Expanded Tropism Independent of gD Activation by Its Receptors

artículo científico publicado en 2015

The UL20 gene of herpes simplex virus 1 encodes a function necessary for viral egress

artículo científico publicado en 1991

The V domain of herpesvirus Ig-like receptor (HIgR) contains a major functional region in herpes simplex virus-1 entry into cells and interacts physically with the viral glycoprotein D

artículo científico publicado en 1998

The domains of glycoprotein D required to block apoptosis induced by herpes simplex virus 1 are largely distinct from those involved in cell-cell fusion and binding to nectin1

artículo científico publicado en 2003

The ectodomain of a novel member of the immunoglobulin subfamily related to the poliovirus receptor has the attributes of a bona fide receptor for herpes simplex virus types 1 and 2 in human cells

artículo científico publicado en 1998

The ectodomain of herpes simplex virus glycoprotein H contains a membrane alpha-helix with attributes of an internal fusion peptide, positionally conserved in the herpesviridae family

artículo científico publicado en 2005

The egress of alphaherpesviruses from the cell ⬇️

artículo científico publicado el 25 de febrero de 2011

The egress of herpesviruses from cells: the unanswered questions

artículo científico publicado en 2006

The epithelial αvβ3-integrin boosts the MYD88-dependent TLR2 signaling in response to viral and bacterial components

artículo científico publicado en 2014

The glycoprotein B homologue of human herpesvirus 6.

artículo científico publicado en 1993

The herpes simplex virus JMP mutant enters receptor-negative J cells through a novel pathway independent of the known receptors nectin1, HveA, and nectin2.

artículo científico publicado en 2004

The herpes simplex virus UL20 protein compensates for the differential disruption of exocytosis of virions and viral membrane glycoproteins associated with fragmentation of the Golgi apparatus

artículo científico publicado en 1994

The herpesvirus glycoproteins B and H.L are sequentially recruited to the receptor-bound gD to effect membrane fusion at virus entry

scholarly article

The herpesvirus glycoproteins B and H.L are sequentially recruited to the receptor-bound gD to effect membrane fusion at virus entry.

artículo científico publicado en 2006

The importance of entering cells, non-trivial solutions for serious viruses ⬇️

artículo científico publicado el 1 de febrero de 2012

The molecular basis of herpesviruses as oncolytic agents

artículo científico publicado en 2012

The multipartite system that mediates entry of herpes simplex virus into the cell

artículo científico publicado en 2007

The murine homolog of human Nectin1delta serves as a species nonspecific mediator for entry of human and animal alpha herpesviruses in a pathway independent of a detectable binding to gD

artículo científico publicado en 2000

The novel receptors that mediate the entry of herpes simplex viruses and animal alphaherpesviruses into cells.

artículo científico publicado en 2000

The pro-fusion domain of herpes simplex virus glycoprotein D (gD) interacts with the gD N terminus and is displaced by soluble forms of viral receptors

artículo científico publicado en 2005

The soluble ectodomain of herpes simplex virus gD contains a membrane-proximal pro-fusion domain and suffices to mediate virus entry

artículo científico publicado en 2004

Trafficking to the plasma membrane of the seven-transmembrane protein encoded by human herpesvirus 6 U51 gene involves a cell-specific function present in T lymphocytes.

artículo científico publicado en 1999

Type I interferon and NF-κB activation elicited by herpes simplex virus gH/gL via αvβ3 integrin in epithelial and neuronal cell lines

artículo científico publicado en 2013

UL27.5 is a novel gamma2 gene antisense to the herpes simplex virus 1 gene encoding glycoprotein B.

artículo científico publicado en 1998

Updates and achievements in virology

artículo científico publicado en 2010

Viral and cellular contributions to herpes simplex virus entry into the cell

artículo científico

Virus receptor arrays, CD46 and human herpesvirus 6.

artículo científico publicado en 2000

oHSV Genome Editing by Means of galK Recombineering

artículo científico publicado en 2020

{alpha}V{beta}3-integrin routes herpes simplex virus to an entry pathway dependent on cholesterol-rich lipid rafts and dynamin2.

artículo científico publicado en 2010

αVβ3-integrin relocalizes nectin1 and routes herpes simplex virus to lipid rafts

artículo científico publicado en 2011

αvβ3 Integrin Boosts the Innate Immune Response Elicited in Epithelial Cells through Plasma Membrane and Endosomal Toll-Like Receptors

artículo científico publicado en 2016

αvβ3-integrin is a major sensor and activator of innate immunity to herpes simplex virus-1.

artículo científico publicado en 2012

αvβ3-integrin regulates PD-L1 expression and is involved in cancer immune evasion

artículo científico publicado en 2019

αvβ6- and αvβ8-integrins serve as interchangeable receptors for HSV gH/gL to promote endocytosis and activation of membrane fusion

artículo científico publicado en 2013

Lista de obras de Gabriella Campadelli-Fiume

A Heptad Repeat in Herpes Simplex Virus 1 gH, Located Downstream of the α-Helix with Attributes of a Fusion Peptide, Is Critical for Virus Entry and Fusion.

A Strategy for Cultivation of Retargeted Oncolytic Herpes Simplex Viruses in Non-cancer Cells

A fully-virulent retargeted oncolytic HSV armed with IL-12 elicits local immunity and vaccine therapy towards distant tumors

A heptad repeat in herpes simplex virus 1 gH, located downstream of the alpha-helix with attributes of a fusion peptide, is critical for virus entry and fusion

A herpes simplex virus recombinant that exhibits a single-chain antibody to HER2/neu enters cells through the mammary tumor receptor, independently of the gD receptors

Absence of human herpesvirus 6 and 7 from spinal fluid and serum of multiple sclerosis patients

Alphaherpes viral genes and their functions

Anti-idiotypic antibodies mimicking glycoprotein D of herpes simplex virus identify a cellular protein required for virus spread from cell to cell and virus-induced polykaryocytosis

CD68+ cells of monocyte/macrophage lineage in the environment of AIDS-associated and classic-sporadic Kaposi sarcoma are singly or doubly infected with human herpesviruses 7 and 6B.

Cell-to-cell spread of wild-type herpes simplex virus type 1, but not of syncytial strains, is mediated by the immunoglobulin-like receptors that mediate virion entry, nectin1 (PRR1/HveC/HIgR) and nectin2 (PRR2/HveB)

Characterization of human herpesvirus-6(U1102) and (GS) gp112 and identification of the Z29-specified homolog

Chimeric nectin1-poliovirus receptor molecules identify a nectin1 region functional in herpes simplex virus entry

Coexpression of UL20p and gK inhibits cell-cell fusion mediated by herpes simplex virus glycoproteins gD, gH-gL, and wild-type gB or an endocytosis-defective gB mutant and downmodulates their cell surface expression

Comparison of murine and human nectin1 binding to herpes simplex virus glycoprotein D (gD) reveals a weak interaction of murine nectin1 to gD and a gD-dependent pathway of entry.

Complexes between herpes simplex virus glycoproteins gD, gB, and gH detected in cells by complementation of split enhanced green fluorescent protein

Conservation of the architecture of the Golgi apparatus related to a differential organization of microtubules in polykaryocytes induced by syn- mutants of herpes simplex virus 1.

Construction of a fully retargeted herpes simplex virus 1 recombinant capable of entering cells solely via human epidermal growth factor receptor 2.

Critical residues in the CC' ridge of the human nectin1 receptor V domain enable herpes simplex virus entry into the cell and act synergistically with the downstream region

Cross talk among the glycoproteins involved in herpes simplex virus entry and fusion: the interaction between gB and gH/gL does not necessarily require gD.

Development of recombinant diagnostic reagents based on pp85(U14) and p86(U11) proteins to detect the human immune response to human herpesvirus 7 infection.

Dissociation of HSV gL from gH by αvβ6- or αvβ8-integrin promotes gH activation and virus entry

Dual Ligand Insertion in gB and gD of Oncolytic Herpes Simplex Viruses for Retargeting to a Producer Vero Cell Line and to Cancer Cells

Entry of alphaherpesviruses into the cell

Entry of herpes simplex virus mediated by chimeric forms of nectin1 retargeted to endosomes or to lipid rafts occurs through acidic endosomes

Eradication of glioblastoma by immuno-virotherapy with a retargeted oncolytic HSV in a preclinical model

Glycoprotein C-dependent attachment of herpes simplex virus to susceptible cells leading to productive infection

Glycoprotein D of bovine herpesvirus 5 (BoHV-5) confers an extended host range to BoHV-1 but does not contribute to invasion of the brain

Glycoprotein D of herpes simplex virus encodes a domain which precludes penetration of cells expressing the glycoprotein by superinfecting herpes simplex virus

Glycoprotein D or J delivered in trans blocks apoptosis in SK-N-SH cells induced by a herpes simplex virus 1 mutant lacking intact genes expressing both glycoproteins

HSV as A Platform for the Generation of Retargeted, Armed, and Reporter-Expressing Oncolytic Viruses

Heptad Repeat 2 in Herpes Simplex Virus 1 gH Interacts with Heptad Repeat 1 and Is Critical for Virus Entry and Fusion.

Heptad repeat 2 in herpes simplex virus 1 gH interacts with heptad repeat 1 and is critical for virus entry and fusion

Herpes simplex virus envelopment and maturation studied by fracture label.

Herpes simplex virus gD forms distinct complexes with fusion executors gB and gH/gL in part through the C-terminal profusion domain

Herpes simplex virus glycoprotein K, but not its syncytial allele, inhibits cell-cell fusion mediated by the four fusogenic glycoproteins, gD, gB, gH, and gL.

Herpes simplex virus glycoproteins H/L bind to cells independently of {alpha}V{beta}3 integrin and inhibit virus entry, and their constitutive expression restricts infection

Herpes simplex virus glycoproteins gH/gL and gB bind Toll-like receptor 2, and soluble gH/gL is sufficient to activate NF-κB

Human herpesvirus 6 envelope glycoproteins B and H-L complex are undetectable on the plasma membrane of infected lymphocytes

Human herpesvirus 6: An emerging pathogen.

Human herpesvirus-6 glycoprotein H and L homologs are components of the gp100 complex and the gH external domain is the target for neutralizing monoclonal antibodies

Human nectin3/PRR3: a novel member of the PVR/PRR/nectin family that interacts with afadin

Hydrophobic alpha-helices 1 and 2 of herpes simplex virus gH interact with lipids, and their mimetic peptides enhance virus infection and fusion

Hydrophobic α-Helices 1 and 2 of Herpes Simplex Virus gH Interact with Lipids, and Their Mimetic Peptides Enhance Virus Infection and Fusion.

Identification of an 85 kDa phosphoprotein as an immunodominant protein specific for human herpesvirus 7-infected cells

Increased expression of human herpesvirus 7 in lymphoid organs of AIDS patients

Inhibition of human tumor growth in mice by an oncolytic herpes simplex virus designed to target solely HER-2-positive cells

Insertion of a ligand to HER2 in gB retargets HSV tropism and obviates the need for activation of the other entry glycoproteins.

Integrins as Herpesvirus Receptors and Mediators of the Host Signalosome.

Intermediate forms of glycoconjugates are present in the envelope of herpes simplex virions during their transport along the exocytic pathway

Intracellular trafficking and maturation of herpes simplex virus type 1 gB and virus egress require functional biogenesis of multivesicular bodies

Is pityriasis rosea skin healthier than healthy skin?

Localization and putative function of the UL20 membrane protein in cells infected with herpes simplex virus 1.

Mapping of herpes simplex virus 1 genes with mutations which overcome host restrictions to infection

Monoclonal antibodies to glycoprotein B differentiate human herpesvirus 6 into two clusters, variants A and B.

Monoclonal antibodies to gp100 inhibit penetration of human herpesvirus 6 and polykaryocyte formation in susceptible cells

Nectin2alpha (PRR2alpha or HveB) and nectin2delta are low-efficiency mediators for entry of herpes simplex virus mutants carrying the Leu25Pro substitution in glycoprotein D

Novel, soluble isoform of the herpes simplex virus (HSV) receptor nectin1 (or PRR1-HIgR-HveC) modulates positively and negatively susceptibility to HSV infection

Oncolytic herpes virus retargeted to HER-2.

Origin of unenveloped capsids in the cytoplasm of cells infected with herpes simplex virus 1

Persistence of human herpesvirus 7 in normal tissues detected by expression of a structural antigen

Pityriasis rosea is not associated with human herpesvirus 7.

Polyvalent and monoclonal antibodies identify major immunogenic proteins specific for human herpesvirus 7-infected cells and have weak cross-reactivity with human herpesvirus 6

Preclinical therapy of disseminated HER-2⁺ ovarian and breast carcinomas with a HER-2-retargeted oncolytic herpesvirus.

Prominent role of the Ig-like V domain in trans-interactions of nectins. Nectin3 and nectin 4 bind to the predicted C-C'-C"-D beta-strands of the nectin1 V domain

Redistribution of microtubules and Golgi apparatus in herpes simplex virus-infected cells and their role in viral exocytosis.

Replication-competent herpes simplex virus retargeted to HER2 as therapy for high-grade glioma

Replicative conditioning of Herpes simplex type 1 virus by Survivin promoter, combined to ERBB2 retargeting, improves tumour cell-restricted oncolysis

Rescue, Purification, and Characterization of a Recombinant HSV Expressing a Transgenic Protein

Retargeted and Multi-cytokine-Armed Herpes Virus Is a Potent Cancer Endovaccine for Local and Systemic Anti-tumor Treatment

Retargeting Strategies for Oncolytic Herpes Simplex Viruses

Rethinking herpes simplex virus: the way to oncolytic agents

Selection of a monoclonal antibody specific for variant B human herpesvirus 6-infected mononuclear cells

Simultaneous Insertion of Two Ligands in gD for Cultivation of Oncolytic Herpes Simplex Viruses in Noncancer Cells and Retargeting to Cancer Receptors

Spotlight on… Gabriella Campadelli-Fiume.

Substitution in the murine nectin1 receptor of a single conserved amino acid at a position distal from the herpes simplex virus gD binding site confers high-affinity binding to gD.

Systemic delivery of HER2-retargeted oncolytic-HSV by mesenchymal stromal cells protects from lung and brain metastases

The 85-kilodalton phosphoprotein (pp85) of human herpesvirus 7 is encoded by open reading frame U14 and localizes to a tegument substructure in virion particles.

The Ectodomain of Herpes Simplex Virus Glycoprotein H Contains a Membrane α-Helix with Attributes of an Internal Fusion Peptide, Positionally Conserved in the Herpesviridae Family.

The Engineering of a Novel Ligand in gH Confers to HSV an Expanded Tropism Independent of gD Activation by Its Receptors