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Lista de obras de Peter Lichter

3D geometry-based quantification of colocalizations in multichannel 3D microscopy images of human soft tissue tumors

artículo científico publicado en 2010

A biologic definition of Burkitt's lymphoma from transcriptional and genomic profiling.

artículo científico publicado en 2006

A cell-based model system links chromothripsis with hyperploidy

artículo científico publicado en 2015

A chromosome 8 gene-cluster polymorphism with low human beta-defensin 2 gene copy number predisposes to Crohn disease of the colon

artículo científico publicado en 2006

A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing.

artículo científico publicado en 2015

A comprehensive multicenter comparison of whole genome sequencing pipelines using a uniform tumor-normal sample pair

A gene signature distinguishing CD133hi from CD133- colorectal cancer cells: essential role for EGR1 and downstream factors

artículo científico publicado en 2011

A mammalian microRNA expression atlas based on small RNA library sequencing

artículo científico publicado en 2007

A novel cloning strategy for one-step assembly of multiplex CRISPR vectors

artículo científico publicado en 2018

Abstract 3089: (Epi)genetic profiling enables molecular re-classification of CNS-primitive neuroectodermal tumors

Abstract 3094: Epigenetic classification of ependymal brain tumors across age groups

Accumulation of genomic aberrations during clinical progression of medulloblastoma

artículo científico publicado en 2008

Acromegaly Caused by Secretion of Growth Hormone by a Non-Hodgkin's Lymphoma

Activation of MAP kinase signaling through ERK5 but not ERK1 expression is associated with lymph node metastases in oral squamous cell carcinoma (OSCC).

artículo científico publicado en 2008

Active medulloblastoma enhancers reveal subgroup-specific cellular origins

artículo científico publicado en 2016

Acute myeloid leukemia is propagated by a leukemic stem cell with lymphoid characteristics in a mouse model of CALM/AF10-positive leukemia

artículo científico publicado en 2006

Additional genetic high-risk features such as 11q deletion, 17p deletion, and V3-21 usage characterize discordance of ZAP-70 and VH mutation status in chronic lymphocytic leukemia

artículo científico publicado en 2006

Adult and pediatric medulloblastomas are genetically distinct and require different algorithms for molecular risk stratification

artículo científico publicado en 2010

Adult medulloblastoma comprises three major molecular variants.

artículo científico publicado en 2011

After 50 years: Future challenges in publishing cancer research

artículo científico publicado en 2016

Ala228 variant of trail receptor 1 affecting the ligand binding site is associated with chronic lymphocytic leukemia, mantle cell lymphoma, prostate cancer, head and neck squamous cell carcinoma and bladder cancer

All you need is a Mir-acle: the role of nontranslated RNAs in the suppression of B cell chronic lymphocytic leukemia

artículo científico publicado en 2010

Allelic silencing at the tumor-suppressor locus 13q14.3 suggests an epigenetic tumor-suppressor mechanism

artículo científico publicado en 2006

An activated mutant BRAF kinase domain is sufficient to induce pilocytic astrocytoma in mice

artículo científico publicado en 2011

Analysis of 11q22-q23 deletion target genes in B-cell chronic lymphocytic leukaemia: evidence for a pathogenic role of NPAT, CUL5, and PPP2R1B.

artículo científico publicado en 2007

Antagonizing inactivated tumor suppressor genes and activated oncogenes by a versatile transgenesis system: application in mantle cell lymphoma

artículo científico publicado en 2006

Antiapoptotic function of charged multivesicular body protein 5: A potentially relevant gene in acute myeloid leukemia ⬇️

artículo científico publicado el 19 de octubre de 2010

Array-based profiling of reference-independent methylation status (aPRIMES) identifies frequent promoter methylation and consecutive downregulation of ZIC2 in pediatric medulloblastoma

artículo científico publicado en 2007

Assembly and mobility of exon-exon junction complexes in living cells

artículo científico publicado en 2009

Assessment of differentiation and progression of hepatic tumors using array-based comparative genomic hybridization

artículo científico publicado en 2006

Association of Stem Cell-Related Markers and Survival in Astrocytic Gliomas ⬇️

artículo científico publicado el 1 de marzo de 2011

Atypical Teratoid/Rhabdoid Tumors Are Comprised of Three Epigenetic Subgroups with Distinct Enhancer Landscapes

artículo científico publicado en 2016

Author Correction: BCAT1 restricts αKG levels in AML stem cells leading to IDH-like DNA hypermethylation

artículo científico publicado en 2018

Author Correction: BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation

artículo científico publicado en 2018

Author Correction: The landscape of genomic alterations across childhood cancers

artículo científico publicado en 2018

Automated array-based genomic profiling in chronic lymphocytic leukemia: development of a clinical tool and discovery of recurrent genomic alterations

artículo científico publicado en 2004

Automated screening for genomic imbalances using matrix-based comparative genomic hybridization

artículo científico publicado en 2002

BCAT1 promotes cell proliferation through amino acid catabolism in gliomas carrying wild-type IDH1.

artículo científico publicado en 2013

BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation

artículo científico publicado en 2017

BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas

artículo científico publicado en 2008

Biological and clinical heterogeneity of MYCN-amplified medulloblastoma.

artículo científico publicado en 2011

Branched-chain ketoacids secreted by glioblastoma cells via MCT1 modulate macrophage phenotype

artículo científico publicado en 2017

CD24 Ala57Val polymorphism predicts pathologic complete response to sequential anthracycline- and taxane-based neoadjuvant chemotherapy for primary breast cancer

artículo científico publicado en 2011

CITED4 gene silencing in colorectal cancer cells modulates adherens/tight junction gene expression and reduces cell proliferation

artículo científico publicado en 2015

Candidate genes for cross-resistance against DNA-damaging drugs.

artículo científico publicado en 2002

Candidate genes in breast cancer revealed by microarray-based comparative genomic hybridization of archived tissue.

artículo científico

Capture and Amplification by Tailing and Switching (CATS). An ultrasensitive ligation-independent method for generation of DNA libraries for deep sequencing from picogram amounts of DNA and RNA

artículo científico publicado en 2014

Characterization of a nuclear compartment shared by nuclear bodies applying ectopic protein expression and correlative light and electron microscopy.

artículo científico publicado en 2005

Characterization of nuclear compartments identified by ectopic markers in mammalian cells with distinctly different karyotype.

artículo científico publicado en 2005

Chromothripsis in cancer cells: An update

artículo científico

Claes Lundsteen—in Memoriam

Classical Hodgkin lymphoma is characterized by recurrent copy number gains of the short arm of chromosome 2.

artículo científico publicado en 2002

Clonal evolution in chronic lymphocytic leukemia: acquisition of high-risk genomic aberrations associated with unmutated VH, resistance to therapy, and short survival

artículo científico publicado en 2007

Clonal heterogeneity in childhood myelodysplastic syndromes--challenge for the detection of chromosomal imbalances by array-CGH

artículo científico publicado en 2010

Comparative expressed sequence hybridization detects recurrent patterns of altered sequence expression in oral squamous cell carcinoma

artículo científico publicado en 2010

Comparative gene mapping in cattle, Indian muntjac, and Chinese muntjac by fluorescence in situ hybridization.

artículo científico publicado en 2008

Comparative integrated molecular analysis of intraocular medulloepitheliomas and central nervous system embryonal tumors with multilayered rosettes confirms that they are distinct nosologic entities

artículo científico publicado en 2015

Comparative sequence and expression analyses of four mammalian VPS4 genes

artículo científico publicado en 2003

Comprehensive analysis of genomic alterations in gliosarcoma and its two tissue components

artículo científico publicado en 2002

Comprehensive characterization of genomic aberrations in gangliogliomas by CGH, array-based CGH and interphase FISH.

artículo científico publicado en 2008

Conflicts of interest: the responsibility of the authors and editors of the International Journal of Cancer.

artículo científico publicado en 2006

Copy number alterations in childhood acute lymphoblastic leukemia and their association with minimal residual disease

Copy number gains on 22q13 in adenoid cystic carcinoma of the salivary gland revealed by comparative genomic hybridization and tissue microarray analysis

scientific article published on 01 May 2005

Corrigendum: Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

artículo científico publicado en 2012

Coverage bias and sensitivity of variant calling for four whole-genome sequencing technologies

artículo científico publicado en 2013

Cytogenetic and molecular genetic analyses of giant cell glioblastoma multiforme reveal distinct profiles in giant cell and non-giant cell subpopulations

artículo científico publicado en 2007

Cytogenetic characterization of head and neck squamous cell carcinoma cell lines as model systems for the functional analyses of tumor-associated genes

artículo científico publicado en 2010

DIPG-22. IDENTIFICATION OF THERAPEUTIC TARGETS IN DIPGS USING LARGE-SCALE RNAI SCREENING.

artículo científico publicado en 2017

DNA hypermethylation and aberrant expression of the EMP3 gene at 19q13.3 in Human Gliomas

artículo científico publicado en 2007

DNA methylation dynamics during B cell maturation underlie a continuum of disease phenotypes in chronic lymphocytic leukemia

artículo científico publicado en 2016

DNA methylation-based classification of central nervous system tumours.

artículo científico publicado en 2018

DNA methylome analysis in Burkitt and follicular lymphomas identifies differentially methylated regions linked to somatic mutation and transcriptional control

artículo científico publicado en 2015

Decoding the regulatory landscape of medulloblastoma using DNA methylation sequencing

artículo científico publicado en 2014

Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma

artículo científico publicado en 2011

Detection of chromosomal imbalances in retinoblastoma by matrix-based comparative genomic hybridization

artículo científico publicado en 2005

Development of a mantle cell lymphoma in an ATM heterozygous woman after occupational exposure to ionising radiation and somatic mutation of the second allele.

artículo científico publicado en 2006

Differential KIT expression in histological subtypes of adenoid cystic carcinoma (ACC) of the salivary gland.

artículo científico publicado en 2005

Differential expression and methylation of brain developmental genes define location-specific subsets of pilocytic astrocytoma

artículo científico

Differential retinoic acid signaling in tumors of long- and short-term glioblastoma survivors.

artículo científico publicado en 2011

Differentiation therapy exerts antitumor effects on stem-like glioma cells

artículo científico publicado en 2010

Diffusion-limited compartmentalization of mammalian cell nuclei assessed by microinjected macromolecules ⬇️

artículo científico publicado el 1 de octubre de 2003

Disclosure of Candidate Genes in Acute Myeloid Leukemia With Complex Karyotypes Using Microarray-Based Molecular Characterization

Dissecting the genomic complexity underlying medulloblastoma

artículo científico publicado en 2012

Distinct chromosomal imbalances in pleomorphic and in high-grade dedifferentiated liposarcomas

artículo científico publicado en 2002

Distinct gene expression patterns associated with FLT3- and NRAS-activating mutations in acute myeloid leukemia with normal karyotype

artículo científico publicado en 2005

Distinct gene expression patterns in chronic lymphocytic leukemia defined by usage of specific VH genes.

artículo científico publicado en 2005

Distinct site-specific oncoprotein overexpression in head and neck squamous cell carcinoma: a tissue microarray analysis

scientific article published on 01 September 2003

Down-regulation of candidate tumor suppressor genes within chromosome band 13q14.3 is independent of the DNA methylation pattern in B-cell chronic lymphocytic leukemia

artículo científico publicado en 2002

Doxorubicin/Pemetrexed Followed by Docetaxel Versus Doxorubicin/Cyclophosphamide Followed by Docetaxel as Neoadjuvant Treatment for Early-Stage Breast Cancer: A Randomized Phase II Trial

artículo científico publicado en 2007

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

artículo científico publicado en 2012

Dynamic mathematical modeling of IL13-induced signaling in Hodgkin and primary mediastinal B-cell lymphoma allows prediction of therapeutic targets

artículo científico publicado en 2010

Dynamics of telomeres and promyelocytic leukemia nuclear bodies in a telomerase-negative human cell line

artículo científico publicado en 2009

EP-03MOLECULAR CLASSIFICATION OF EPENDYMAL TUMORS ACROSS ALL CNS COMPARTMENTS, HISTOPATHOLOGICAL GRADES AND AGE GROUPS.

artículo científico publicado en 2015

Effective transcriptome amplification for expression profiling on sense-oriented oligonucleotide microarrays

artículo científico publicado en 2005

Elastic SCAD as a novel penalization method for SVM classification tasks in high-dimensional data ⬇️

artículo científico publicado en 2011

Elevated NF-kappaB p50 complex formation and Bcl-3 expression in classical Hodgkin, anaplastic large-cell, and other peripheral T-cell lymphomas

artículo científico publicado en 2005

Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma

artículo científico publicado en 2014

Epigenetic upregulation of lncRNAs at 13q14.3 in leukemia is linked to the In Cis downregulation of a gene cluster that targets NF-kB.

artículo científico publicado en 2013

Epithelioid glioblastomas stratify into established diagnostic subsets upon integrated molecular analysis.

artículo científico publicado en 2017

Erratum to: Gliomatosis cerebri: no evidence for a separate brain tumor entity

artículo científico publicado en 2016

Erratum: Corrigendum: Signatures of mutational processes in human cancer

artículo científico publicado en 2013

Establishment, characterization and drug sensitivity testing in primary cultures of human thymoma and thymic carcinoma.

artículo científico publicado en 2008

Estrogen-related receptor alpha expression and function is associated with the transcriptional coregulator AIB1 in breast carcinoma

artículo científico publicado en 2009

Etiology-dependent molecular mechanisms in human hepatocarcinogenesis

artículo científico publicado en 2008

Evidence for distinct pathomechanisms in B-cell chronic lymphocytic leukemia and mantle cell lymphoma by quantitative expression analysis of cell cycle and apoptosis-associated genes

artículo científico publicado en 2002

Evidence for distinct pathomechanisms in genetic subgroups of chronic lymphocytic leukemia revealed by quantitative expression analysis of cell cycle, activation, and apoptosis-associated genes

artículo científico publicado en 2005

Evolution of DNA methylation is linked to genetic aberrations in chronic lymphocytic leukemia

artículo científico publicado en 2013

Experimental evidence for the influence of molecular crowding on nuclear architecture

artículo científico publicado en 2007

Exploiting biological diversity and genomic aberrations in chronic lymphocytic leukemia

artículo científico publicado en 2011

Expression of centrosome-associated gene products is linked to tetraploidization in mantle cell lymphoma.

artículo científico publicado en 2007

Expression of podoplanin in human astrocytic brain tumors is controlled by the PI3K-AKT-AP-1 signaling pathway and promoter methylation

artículo científico publicado en 2012

Extracellular vesicles in chronic lymphocytic leukemia

artículo científico publicado en 2013

FACT--a framework for the functional interpretation of high-throughput experiments

artículo científico publicado en 2005

FARP2, HDLBP and PASK are downregulated in a patient with autism and 2q37.3 deletion syndrome

scholarly article by Bärbel Felder et al published 13 April 2009 in American Journal of Medical Genetics

FSTL5 is a marker of poor prognosis in non-WNT/non-SHH medulloblastoma

artículo científico publicado en 2011

Focal genomic amplification at 19q13.42 comprises a powerful diagnostic marker for embryonal tumors with ependymoblastic rosettes.

artículo científico publicado en 2010

Frequent amplifications and abundant expression of TRIO, NKD2, and IRX2 in soft tissue sarcomas

artículo científico publicado en 2006

Frequent high telomerase reverse transcriptase expression in primary oral squamous cell carcinoma

artículo científico publicado en 2007

Functional screening for proapoptotic genes by reverse transfection cell array technology

artículo científico publicado en 2006

GE-23ENHANCER HIJACKING ACTIVATES GFI1 FAMILY ONCOGENES IN MEDULLOBLASTOMA.

artículo científico publicado en 2014

Gains of 2p involving the REL locus correlate with nuclear c-Rel protein accumulation in neoplastic cells of classical Hodgkin lymphoma

artículo científico publicado en 2003

Gene Expression Patterns in Ependymomas Correlate with Tumor Location, Grade, and Patient Age ⬇️

artículo científico publicado el 1 de noviembre de 2003

Gene expression factors as predictors of genetic risk and survival in chronic lymphocytic leukemia

artículo científico publicado en 2009

Gene expression patterns in acute myeloid leukemia correlate with centrosome aberrations and numerical chromosome changes

artículo científico publicado en 2004

Gene expression signature predicting pathologic complete response with gemcitabine, epirubicin, and docetaxel in primary breast cancer.

artículo científico publicado en 2006

Gene mutations and treatment outcome in chronic lymphocytic leukemia: results from the CLL8 trial.

artículo científico publicado en 2014

Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition

artículo científico publicado en 2014

Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations

artículo científico publicado en 2012

Genome-wide identification of translationally inhibited and degraded miR-155 targets using RNA-interacting protein-IP.

artículo científico publicado en 2013

Genomic DNA-chip hybridization in t(11;14)-positive mantle cell lymphomas shows a high frequency of aberrations and allows a refined characterization of consensus regions

artículo científico publicado en 2004

Genomic DNA-chip hybridization reveals a higher incidence of genomic amplifications in pancreatic cancer than conventional comparative genomic hybridization and leads to the identification of novel candidate genes

artículo científico publicado en 2004

Genomic aberrations in mantle cell lymphoma detected by interphase fluorescence in situ hybridization. Incidence and clinicopathological correlations

artículo científico publicado en 2008

Genomic and expression profiling of glioblastoma stem cell-like spheroid cultures identifies novel tumor-relevant genes associated with survival

artículo científico publicado en 2009

Genomic and protein expression profiling identifies CDK6 as novel independent prognostic marker in medulloblastoma

artículo científico publicado en 2005

Genomic and transcriptomic analyses match medulloblastoma mouse models to their human counterparts

artículo científico publicado en 2014

Genomic organization, splice products and mouse chromosomal localization of genes for transcription factor Nuclear Factor One

artículo científico publicado en 2003

Gliomatosis cerebri: no evidence for a separate brain tumor entity

artículo científico publicado en 2015

HMGB1 inhibits cell death in yeast and mammalian cells and is abundantly expressed in human breast carcinoma

artículo científico publicado en 2003

Hardware and software requirements for quantitative analysis of comparative genomic hybridization

article

Hidden gene amplifications in aggressive B-cell non-Hodgkin lymphomas detected by microarray-based comparative genomic hybridization

artículo científico publicado en 2003

High survivin expression is associated with favorable outcome in advanced primary oral squamous cell carcinoma after radiation therapy

artículo científico publicado en 2007

High-resolution genomic profiling of childhood T-ALL reveals frequent copy-number alterations affecting the TGF-beta and PI3K-AKT pathways and deletions at 6q15-16.1 as a genomic marker for unfavorable early treatment response

artículo científico publicado en 2009

High-resolution genomic profiling reveals association of chromosomal aberrations on 1q and 16p with histologic and genetic subgroups of invasive breast cancer.

artículo científico publicado en 2006

Histologically distinct neuroepithelial tumors with histone 3 G34 mutation are molecularly similar and comprise a single nosologic entity

artículo científico publicado en 2015

Histone acetylation increases chromatin accessibility

artículo científico publicado en 2005

Hodgkin's lymphoma cell lines are characterized by frequent aberrations on chromosomes 2p and 9p including REL and JAK2.

artículo científico

Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma

artículo científico publicado en 2012

Hypermutation of the inactive X chromosome is a frequent event in cancer

artículo científico publicado en 2013

ICGC PedBrain - dissecting the genomic complexity underlying medulloblastoma using whole-genome sequencing.

artículo científico publicado en 2012

IGF2 knockdown in two colorectal cancer cell lines decreases survival, adhesion and modulates survival-associated genes

artículo científico publicado en 2016

IJC 2016

artículo científico publicado en 2016

Identification of gains on 1q and epidermal growth factor receptor overexpression as independent prognostic markers in intracranial ependymoma

artículo científico publicado en 2006

Identification of novel AP-1 target genes in fibroblasts regulated during cutaneous wound healing.

artículo científico publicado en 2004

Identification of novel oligodendroglioma-associated candidate tumor suppressor genes in 1p36 and 19q13 using microarray-based expression profiling.

artículo científico publicado en 2006

In situ hybridization and detection using nonisotopic probes

artículo científico publicado en 2007

In situ hybridization to metaphase chromosomes and interphase nuclei.

artículo científico publicado en 2005

In vivo BiFC analysis of Y14 and NXF1 mRNA export complexes: preferential localization within and around SC35 domains

artículo científico publicado en 2006

Independent molecular development of metachronous glioblastomas with extended intervening recurrence-free interval.

artículo científico publicado en 2003

Inflammatory cytokines and signaling pathways are associated with survival of primary chronic lymphocytic leukemia cells in vitro: a dominant role of CCL2 ⬇️

artículo científico publicado el 6 de diciembre de 2010

Integrated DNA methylation and copy-number profiling identify three clinically and biologically relevant groups of anaplastic glioma

artículo científico publicado en 2014

Integrated analysis of pediatric glioblastoma reveals a subset of biologically favorable tumors with associated molecular prognostic markers

artículo científico publicado en 2015

Integrative DNA methylation and gene expression analysis in high-grade soft tissue sarcomas

artículo científico publicado en 2013

International network of cancer genome projects

artículo científico publicado en 2010

Internationales Krebsgenomkonsortium (ICGC)

article

Investigation of nuclear architecture with a domain-presenting expression system

artículo científico publicado en 2002

Isochromosome breakpoints on 17p in medulloblastoma are flanked by different classes of DNA sequence repeats

artículo científico publicado en 2006

JunB is required for endothelial cell morphogenesis by regulating core-binding factor beta

artículo científico publicado en 2006

K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas

artículo científico publicado en 2012

Kinome-wide shRNA screen identifies the receptor tyrosine kinase AXL as a key regulator for mesenchymal glioblastoma stem-like cells

artículo científico publicado en 2015

Krüppel-like factor 4 (KLF4) inactivation in chronic lymphocytic leukemia correlates with promoter DNA-methylation and can be reversed by inhibition of NOTCH signaling

artículo científico publicado en 2016

LGR5 is a marker of poor prognosis in glioblastoma and is required for survival of brain cancer stem-like cells

artículo científico publicado en 2012

LIN28A immunoreactivity is a potent diagnostic marker of embryonal tumor with multilayered rosettes (ETMR)

artículo científico publicado en 2012

Lenalidomide reduces survival of chronic lymphocytic leukemia cells in primary cocultures by altering the myeloid microenvironment

artículo científico publicado en 2013

Local gene density predicts the spatial position of genetic loci in the interphase nucleus

article

Loss of SOX2 expression induces cell motility via vimentin up-regulation and is an unfavorable risk factor for survival of head and neck squamous cell carcinoma

artículo científico publicado en 2015

Low-dose Actinomycin-D treatment re-establishes the tumoursuppressive function of P53 in RELA-positive ependymoma

artículo científico publicado en 2016

MAPK pathway activation in pilocytic astrocytoma

artículo científico publicado en 2012

MB-08MOLECULAR (RE-)CLASSIFICATION OF CNS-PRIMITIVE NEUROECTODERMAL TUMORS.

artículo científico publicado en 2015

MOLECULAR (RE-)CLASSIFICATION OF CNS-PRIMITIVE NEUROECTODERMAL TUMORS.

artículo científico publicado en 2014

MPTH-15MOLECULAR RECLASSIFICATION OF CNS-PRIMITIVE NEUROECTODERMAL TUMORS INTO WELL-KNOWN AND NOVEL TUMOR ENTITIES.

artículo científico publicado en 2015

MYC high level gene amplification is a distinctive feature of angiosarcomas after irradiation or chronic lymphedema

artículo científico publicado en 2009

Macromolecular crowding and its potential impact on nuclear function

artículo científico publicado en 2008

Matrix-comparative genomic hybridization from multicenter formalin-fixed paraffin-embedded colorectal cancer tissue blocks

artículo científico publicado en 2007

Mechismo: predicting the mechanistic impact of mutations and modifications on molecular interactions.

artículo científico publicado en 2014

Medulloblastoma Down Under 2013: a report from the third annual meeting of the International Medulloblastoma Working Group.

artículo científico publicado en 2013

Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations

artículo científico publicado en 2012

Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress

artículo científico publicado en 2016

Medulloblastomics: the end of the beginning

scientific article published on December 2012

MicroRNA profiling of primary high-grade soft tissue sarcomas

artículo científico publicado en 2012

MicroRNA-182 promotes leptomeningeal spread of non-sonic hedgehog-medulloblastoma.

artículo científico publicado en 2011

Microarray gene expression profiling of B-cell chronic lymphocytic leukemia subgroups defined by genomic aberrations and VH mutation status

scientific article published on 01 October 2004

Microarray-based copy number and expression profiling in dedifferentiated and pleomorphic liposarcoma

artículo científico publicado en 2002

Microarray-based gene expression profiling of benign, atypical and anaplastic meningiomas identifies novel genes associated with meningioma progression

artículo científico publicado en 2005

Microarray-based genomic profiling reveals novel genomic aberrations in follicular lymphoma which associate with patient survival and gene expression status

article

Microarray-based screening for molecular markers in medulloblastoma revealed STK15 as independent predictor for survival.

artículo científico publicado en 2004

Mobility of multi-subunit complexes in the nucleus: accessibility and dynamics of chromatin subcompartments.

artículo científico publicado en 2005

Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups

artículo científico publicado en 2015

Molecular characterization of AML with ins(21;8)(q22;q22q22) reveals similarity to t(8;21) AML.

artículo científico publicado en 2011

Molecular characterization of medulloblastomas with extensive nodularity (MBEN).

artículo científico publicado en 2018

Molecular classification of human gliomas using matrix-based comparative genomic hybridization

artículo científico publicado en 2005

Molecular signatures classify astrocytic gliomas by IDH1 mutation status.

artículo científico publicado en 2011

Molecular staging of intracranial ependymoma in children and adults

artículo científico publicado en 2010

Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas

artículo científico publicado en 2012

Molecular subgroups of medulloblastoma: the current consensus

artículo científico publicado en 2012

Mutations in regulators of the epigenome and their connections to global chromatin patterns in cancer

artículo científico

NFATC1 activation by DNA hypomethylation in chronic lymphocytic leukemia correlates with clinical staging and can be inhibited by ibrutinib

artículo científico publicado en 2017

Neoadjuvant therapy with gemcitabine in breast cancer

artículo científico publicado en 2004

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

artículo científico publicado en 2016

Next-generation personalised medicine for high-risk paediatric cancer patients - The INFORM pilot study

artículo científico publicado en 2016

No correlation between NF1 mutation position and risk of optic pathway glioma in 77 unrelated NF1 patients

artículo científico publicado en 2016

Nos2 inactivation promotes the development of medulloblastoma in Ptch1(+/-) mice by deregulation of Gap43-dependent granule cell precursor migration

artículo científico publicado en 2012

Novel genomic amplification targeting the microRNA cluster at 19q13.42 in a pediatric embryonal tumor with abundant neuropil and true rosettes.

artículo científico publicado en 2008

Novel oncogene amplifications in tumors from a family with Li-Fraumeni syndrome

artículo científico publicado en 2009

Nuclear RNAs confined to a reticular compartment between chromosome territories

artículo científico publicado en 2005

Nuclear body movement is determined by chromatin accessibility and dynamics

artículo científico publicado en 2004

Obligation for cell line authentication: appeal for concerted action

artículo científico publicado en 2010

Off-target effects of siRNA specific for GFP

artículo científico publicado en 2008

Oncogenic FAM131B-BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma

artículo científico publicado en 2011

Optimization of high-density cDNA-microarray protocols by 'design of experiments'.

artículo científico publicado en 2003

Outcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN loci

artículo científico publicado en 2009

Overexpression of the far upstream element binding protein 1 in hepatocellular carcinoma is required for tumor growth

artículo científico publicado en 2009

P42: High resolution genomic profiling reveals association of chromosomal aberrations on 1q and 16p with histological and genetic subgroups of invasive breast cancer

P45: Comprehensive genomic analysis of desmoplastic medulloblastomas reveals novel amplified genes and supports a monoclonal origin of the different histologic components

article

PCM-15SOMATIC CRISPR/Cas9-MEDIATED TUMOR SUPPRESSOR DISRUPTION ENABLES VERSATILE BRAIN TUMOR MODELING.

artículo científico publicado en 2016

PD-L1 checkpoint blockade prevents immune dysfunction and leukemia development in a mouse model of chronic lymphocytic leukemia

artículo científico publicado en 2015

PNR-21FOUR NEW BRAIN TUMOR ENTITIES EMERGE FROM MOLECULAR CLASSIFICATION OF CNS PNETs

artículo científico publicado en 2016

Paediatric and adult glioblastoma: multiform (epi)genomic culprits emerge

artículo científico publicado en 2014

Patient-based cross-platform comparison of oligonucleotide microarray expression profiles.

artículo científico publicado en 2005

Podoplanin is a novel fos target gene in skin carcinogenesis

artículo científico publicado en 2008

Preeclampsia: increased expression of soluble ADAM 12.

artículo científico publicado en 2005

Profile of gene expression induced by the tumour promotor TPA in murine epithelial cells

artículo científico publicado en 2003

Prognostic significance of clinical, histopathological, and molecular characteristics of medulloblastomas in the prospective HIT2000 multicenter clinical trial cohort

artículo científico publicado en 2014

Protein phosphatase 1, regulatory subunit 15B is a survival factor for ERα-positive breast cancer

artículo científico publicado en 2012

Quantitative gene expression deregulation in mantle-cell lymphoma: correlation with clinical and biologic factors

scientific article published on 11 June 2007

Quantitative proteomics identify novel miR-155 target proteins.

artículo científico publicado en 2011

QuickLIMS: facilitating the data management for DNA-microarray fabrication

artículo científico publicado en 2003

Recollections of a scientific journey published in human genetics: from chromosome territories to interphase cytogenetics and comparative genome hybridization

artículo científico publicado en 2014

Recurrent FGFR1 amplification and high FGFR1 protein expression in oral squamous cell carcinoma (OSCC).

artículo científico publicado en 2006

Recurrent NMYC copy number gain and high protein expression in basal cell carcinoma.

artículo científico publicado en 2006

Recurrent coamplification of cytoskeleton-associated genesEMS1 andSHANK2 withCCND1 in oral squamous cell carcinoma

article

Recurrent copy number gain of transcription factor SOX2 and corresponding high protein expression in oral squamous cell carcinoma.

artículo científico publicado en 2010

Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing

artículo científico publicado en 2012

Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma

artículo científico publicado en 2013

Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas

artículo científico publicado en 2013

Reply to J.C. Lindsey et al

Report: workshop on mediastinal grey zone lymphoma

artículo científico publicado en 2005

Report: workshop on mediastinal grey zone lymphoma

article by Sibrand Poppema et al published 6 June 2005 in European Journal of Haematology

Reprogramming of the ERRα and ERα target gene landscape triggers tamoxifen resistance in breast cancer

artículo científico publicado en 2015

Resistance mechanisms for the Bruton's tyrosine kinase inhibitor ibrutinib

artículo científico publicado en 2014

Robust molecular subgrouping and copy-number profiling of medulloblastoma from small amounts of archival tumour material using high-density DNA methylation arrays

artículo científico publicado en 2013

Role of LIM and SH3 protein 1 (LASP1) in the metastatic dissemination of medulloblastoma

artículo científico publicado en 2010

STRUCTURAL VARIANTS SHUFFLE CHROMATIN TO ACTIVATE GFI1 FAMILY ONCOGENES IN MEDULLOBLASTOMA.

artículo científico publicado en 2014

Severe mental retardation with breathing abnormalities (Pitt-Hopkins syndrome) is caused by haploinsufficiency of the neuronal bHLH transcription factor TCF4.

artículo científico publicado en 2007

Soluble CD14 is a novel monocyte-derived survival factor for chronic lymphocytic leukemia cells, which is induced by CLL cells in vitro and present at abnormally high levels in vivo

artículo científico publicado en 2010

Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling

artículo científico publicado en 2015

Somatic mutations of DICER1 and KMT2D are frequent in intraocular medulloepitheliomas.

artículo científico publicado en 2016

Spatial heterogeneity in medulloblastoma

artículo científico publicado en 2017

Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort.

artículo científico publicado en 2018

Stem cell marker CD133 affects clinical outcome in glioma patients.

artículo científico publicado en 2008

Stepwise accumulation of distinct genomic aberrations in a patient with progressively metastasizing ependymoma

artículo científico publicado en 2009

Supratentorial primitive neuroectodermal tumors of the central nervous system frequently harbor deletions of the CDKN2A locus and other genomic aberrations distinct from medulloblastomas.

artículo científico publicado en 2007

TALEN/CRISPR-mediated engineering of a promoterless anti-viral RNAi hairpin into an endogenous miRNA locus

artículo científico publicado en 2016

TNF receptor signaling is a driver of chronic lymphocytic leukemia that can be therapeutically targeted by the flavonoid wogonin

artículo científico publicado en 2018

TP53 alterations in acute myeloid leukemia with complex karyotype correlate with specific copy number alterations, monosomal karyotype, and dismal outcome

artículo científico publicado en 2011

TP53 mutation is frequently associated with CTNNB1 mutation or MYCN amplification and is compatible with long-term survival in medulloblastoma.

artículo científico publicado en 2010

Targeting atypical protein kinase C iota reduces viability in glioblastoma stem-like cells via a notch signaling mechanism

artículo científico publicado en 2016

Targeting self-renewal in high-grade brain tumors leads to loss of brain tumor stem cells and prolonged survival

artículo científico publicado en 2014

The histone acetyltransferase hMOF is frequently downregulated in primary breast carcinoma and medulloblastoma and constitutes a biomarker for clinical outcome in medulloblastoma

artículo científico publicado en 2008

The landscape of genomic alterations across childhood cancers

artículo científico publicado en 2018

The need for a worldwide consensus for cell line authentication: Experience implementing a mandatory requirement at the International Journal of Cancer

artículo científico publicado en 2017

The nuclear receptor tailless induces long-term neural stem cell expansion and brain tumor initiation

artículo científico publicado en 2010

The nuclear receptor tailless is required for neurogenesis in the adult subventricular zone

artículo científico publicado en 2008

The role of epigenetics in carcinogenesis

artículo científico publicado en 2008

Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling

artículo científico publicado en 2017

Tissue microarray analysis reveals site-specific prevalence of oncogene amplifications in head and neck squamous cell carcinoma

scientific article published on 01 March 2003

Topology of genes and nontranscribed sequences in human interphase nuclei

article

Toward understanding and exploiting tumor heterogeneity

artículo científico publicado en 2015

Translocation t(X;11)(q13;q23) in B-cell chronic lymphocytic leukemia disrupts two novel genes

artículo científico publicado en 2005

Tumor-microenvironment interactions studied by zonal transcriptional profiling of squamous cell lung carcinoma

artículo científico publicado en 2012

V(H) mutation status, CD38 expression level, genomic aberrations, and survival in chronic lymphocytic leukemia.

artículo científico publicado en 2002

VH mutation status and VDJ rearrangement structure in mantle cell lymphoma: correlation with genomic aberrations, clinical characteristics, and outcome.

artículo científico publicado en 2003

Whole exome sequencing reveals that the majority of schwannomatosis cases remain unexplained after excluding SMARCB1 and LZTR1 germline variants

article published in 2014

hMOF histone acetyltransferase is required for histone H4 lysine 16 acetylation in mammalian cells

artículo científico publicado en 2005

miRNA-130a targets ATG2B and DICER1 to inhibit autophagy and trigger killing of chronic lymphocytic leukemia cells

artículo científico publicado en 2012

penalizedSVM: a R-package for feature selection SVM classification

artículo científico publicado en 2009

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