Filtros de búsqueda

Lista de obras de Ralf Bartenschlager

18 BILE ACIDS ENHANCE GENOTYPE 1 HEPATITIS C VIRUS REPLICATION

417 Subgenomic hepatitis C replicon deriving from a clinical isolate with virologic non-response to IFN-based therapy and IFN resistance in vitro

607 NEUTRALIZING HOST RESPONSES IN HEPATITIS C VIRUS INFECTION TARGET VIRAL ENTRY AT POST-BINDING STEPS AND MEMBRANE FUSION

article

A Combined Genetic-Proteomic Approach Identifies Residues within Dengue Virus NS4B Critical for Interaction with NS3 and Viral Replication

artículo científico publicado en 2015

A Comprehensive Structure-Function Comparison of Hepatitis C Virus Strain JFH1 and J6 Polymerases Reveals a Key Residue Stimulating Replication in Cell Culture across Genotypes

artículo científico publicado en 2011

A Novel Cis-Acting RNA Structural Element Embedded in the Core Coding Region of the Hepatitis C Virus Genome Directs Internal Translation Initiation of the Overlapping Core+1 ORF

scientific article published on 22 September 2020

A Novel Inhibitor IDPP Interferes with Entry and Egress of HCV by Targeting Glycoprotein E1 in a Genotype-Specific Manner

artículo científico publicado en 2017

A Proline-Tryptophan Turn in the Intrinsically Disordered Domain 2 of NS5A Protein Is Essential for Hepatitis C Virus RNA Replication

artículo científico publicado en 2015

A Recurrent Neural Network for Particle Tracking in Microscopy Images Using Future Information, Track Hypotheses, and Multiple Detections

artículo científico publicado en 2020

A Reverse Genetics System for Zika Virus Based on a Simple Molecular Cloning Strategy

article

A Slow Maturation Process Renders Hepatitis B Virus Infectious.

artículo científico publicado en 2016

A Versatile Reporter System to Monitor Virus Infected Cells and Its Application to Dengue Virus and SARS-CoV-2

artículo científico publicado en 2020

A concerted action of hepatitis C virus p7 and nonstructural protein 2 regulates core localization at the endoplasmic reticulum and virus assembly

artículo científico publicado en 2011

A conserved NS3 surface patch orchestrates NS2 protease stimulation, NS5A hyperphosphorylation and HCV genome replication

artículo científico publicado en 2015

A major determinant of cyclophilin dependence and cyclosporine susceptibility of hepatitis C virus identified by a genetic approach

artículo científico publicado en 2010

A monocytic detour to replicate patient-derived hepatitis C virus in hepatoma cells and its use for phenotypic analyses

artículo científico publicado en 2015

A novel function for a micro RNA: negative regulators can do positive for the hepatitis C virus

artículo científico publicado en 2006

A novel inhibitor of dengue virus replication that targets the capsid protein

artículo científico publicado en 2012

A novel interaction between dengue virus nonstructural protein 1 and the NS4A-2K-4B precursor is required for viral RNA replication but not for formation of the membranous replication organelle

artículo científico publicado en 2019

A plant-derived flavonoid inhibits entry of all HCV genotypes into human hepatocytes

artículo científico publicado en 2012

A replicon-based bioassay for the measurement of interferons in patients with chronic hepatitis C.

artículo científico publicado en 2003

A reporter cell line for rapid and sensitive evaluation of hepatitis C virus infectivity and replication

artículo científico publicado en 2009

A sensor at the lipid-protein interface: lipid peroxidation controls hepatitis C virus replication

artículo científico publicado en 2015

Activation of Type I and III Interferon Response by Mitochondrial and Peroxisomal MAVS and Inhibition by Hepatitis C Virus

artículo científico publicado en 2015

Adaptation of the hepatitis C virus to cell culture

artículo científico publicado en 2009

Alleviation of off-target effects from vector-encoded shRNAs via codelivered RNA decoys

artículo científico publicado en 2015

Alternative approaches for efficient inhibition of hepatitis C virus RNA replication by small interfering RNAs

artículo científico publicado en 2004

Aminoterminal amphipathic α-helix AH1 of hepatitis C virus nonstructural protein 4B possesses a dual role in RNA replication and virus production

artículo científico publicado en 2014

An in vitro assay for hepatitis C virus NS3 serine proteinase.

artículo científico publicado en 1995

An orthogonal proteomic survey uncovers novel Zika virus host factors

artículo científico publicado en 2018

Analysis of CD8+ T-cell-mediated inhibition of hepatitis C virus replication using a novel immunological model

artículo científico publicado en 2008

Analysis of Hepatitis C Virus Superinfection Exclusion by Using Novel Fluorochrome Gene-Tagged Viral Genomes

artículo científico publicado en 2007

Analysis of Hepatitis C Virus Superinfection Exclusion by Using Novel Fluorochrome Gene-Tagged Viral Genomes.

artículo científico publicado en 2007

Analysis of hepatitis C virus resistance to silibinin in vitro and in vivo points to a novel mechanism involving nonstructural protein 4B.

artículo científico publicado en 2013

Antiviral effects of amantadine and iminosugar derivatives against hepatitis C virus

artículo científico publicado en 2007

Antiviral strategies. Preface

artículo científico publicado en 2009

Apolipoprotein E Mediates Evasion From Hepatitis C Virus Neutralizing Antibodies

artículo científico publicado en 2015

Apolipoprotein E likely contributes to a maturation step of infectious hepatitis C virus particles and interacts with viral envelope glycoproteins

artículo científico publicado en 2014

Application of the trak-C HCV core assay for monitoring antiviral activity in HCV replication systems

artículo científico publicado en 2004

Assembly of infectious hepatitis C virus particles

artículo científico publicado en 2010

Automated Analysis of siRNA Screens of Virus Infected Cells Based on Immunofluorescence Microscopy

Biochemical and kinetic analyses of NS5B RNA-dependent RNA polymerase of the hepatitis C virus.

artículo científico publicado en 1998

Biochemical and morphological properties of hepatitis C virus particles and determination of their lipidome

artículo científico publicado en 2010

Biochemical and structural analysis of the NS5B RNA-dependent RNA polymerase of the hepatitis C virus.

artículo científico publicado en 2000

Biochemical properties of hepatitis C virus NS5B RNA-dependent RNA polymerase and identification of amino acid sequence motifs essential for enzymatic activity ⬇️

artículo científico publicado el 1 de noviembre de 1997

Broad neutralization of hepatitis C virus-resistant variants by Civacir hepatitis C immunoglobulin

artículo científico publicado en 2016

Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

artículo científico publicado en 2005

Cell Culture Adaptation of Hepatitis C Virus and In Vivo Viability of an Adapted Variant

artículo científico publicado en 2007

Cell-free expression, purification, and membrane reconstitution for NMR studies of the nonstructural protein 4B from hepatitis C virus

artículo científico publicado en 2016

Characterization of Determinants Important for Hepatitis C Virus p7 Function in Morphogenesis by Using trans-Complementation

artículo científico publicado en 2009

Characterization of cell lines carrying self-replicating hepatitis C virus RNAs

artículo científico publicado en 2001

Characterization of hepatitis C virus particle subpopulations reveals multiple usage of the scavenger receptor BI for entry steps.

artículo científico publicado en 2012

Characterization of the Early Steps of Hepatitis C Virus Infection by Using Luciferase Reporter Viruses

artículo científico publicado en 2006

Characterization of the hepatitis C virus E2 epitope defined by the broadly neutralizing monoclonal antibody AP33.

artículo científico publicado en 2006

Characterization of the mode of action of a potent dengue virus capsid inhibitor

artículo científico publicado en 2014

Chronic hepatitis C: Portrait of a silent epidemic and the etiologic agent

Chronic viral hepatitis and its association with liver cancer

artículo científico publicado en 2017

Clearance of persistent hepatitis C virus infection in humanized mice using a claudin-1-targeting monoclonal antibody

artículo científico publicado en 2015

Comparative In Vitro Anti-Hepatitis C Virus Activities of a Selected Series of Polymerase, Protease, and Helicase Inhibitors

artículo científico publicado en 2008

Comparative analysis of the lambda-interferons IL-28A and IL-29 regarding their transcriptome and their antiviral properties against hepatitis C virus

artículo científico publicado en 2010

Complex formation between the NS3 serine-type proteinase of the hepatitis C virus and NS4A and its importance for polyprotein maturation

artículo científico publicado en 1995

Conserved RNA secondary structures and long-range interactions in hepatitis C viruses

artículo científico publicado en 2015

Construction and characterization of infectious intragenotypic and intergenotypic hepatitis C virus chimeras

artículo científico publicado en 2006

Control of temporal activation of hepatitis C virus-induced interferon response by domain 2 of nonstructural protein 5A.

artículo científico publicado en 2015

Coordination of Hepatitis C Virus Assembly by Distinct Regulatory Regions in Nonstructural Protein 5A

artículo científico publicado en 2016

Correction: A Conserved NS3 Surface Patch Orchestrates NS2 Protease Stimulation, NS5A Hyperphosphorylation and HCV Genome Replication

artículo científico publicado en 2016

Correction: Essential Role of Cyclophilin A for Hepatitis C Virus Replication and Virus Production and Possible Link to Polyprotein Cleavage Kinetics

article

Correlative light and electron microscopy methods for the study of virus-cell interactions

artículo científico publicado en 2016

Corrigendum: Conserved RNA secondary structures and long-range interactions in hepatitis C viruses

artículo científico publicado en 2016

Critical challenges and emerging opportunities in hepatitis C virus research in an era of potent antiviral therapy: Considerations for scientists and funding agencies.

artículo científico publicado en 2018

Cyclosporine A inhibits hepatitis C virus nonstructural protein 2 through cyclophilin A.

artículo científico publicado en 2009

DEB025 (Alisporivir) inhibits hepatitis C virus replication by preventing a cyclophilin A induced cis-trans isomerisation in domain II of NS5A

artículo científico publicado en 2010

Daclatasvir-like inhibitors of NS5A block early biogenesis of hepatitis C virus-induced membranous replication factories, independent of RNA replication

artículo científico publicado en 2014

Deciphering the Origin and Evolution of Hepatitis B Viruses by Means of a Family of Non-enveloped Fish Viruses

artículo científico publicado en 2017

Dengue Virus Inhibition of Autophagic Flux and Dependency of Viral Replication on Proteasomal Degradation of the Autophagy Receptor p62.

artículo científico publicado en 2015

Dengue Virus Non-structural Protein 1 Modulates Infectious Particle Production via Interaction with the Structural Proteins

artículo científico publicado en 2015

Dengue Virus Perturbs Mitochondrial Morphodynamics to Dampen Innate Immune Responses

artículo científico publicado en 2016

Dengue virus- and hepatitis C virus-induced replication and assembly compartments: the enemy inside--caught in the web.

artículo científico

Deregulation of miR-92a expression is implicated in hepatocellular carcinoma development

artículo científico publicado en 2010

Detecting host factors involved in virus infection by observing the clustering of infected cells in siRNA screening images

artículo científico publicado en 2010

Detection of hepatitis C virus in paraffin-embedded liver biopsies of patients negative for viral RNA in serum

artículo científico publicado en 1999

Determinants of substrate specificity in the NS3 serine proteinase of the hepatitis C virus.

artículo científico publicado en 1997

Development of a high-throughput pyrosequencing assay for monitoring temporal evolution and resistance associated variant emergence in the Hepatitis C virus protease coding-region.

artículo científico publicado en 2014

Discovery of Nanomolar Dengue and West Nile Virus Protease Inhibitors Containing a 4-Benzyloxyphenylglycine Residue

artículo científico publicado en 2015

Discovery of highly divergent lineages of plant-associated astro-like viruses sheds light on the emergence of potyviruses

Discovery of highly divergent lineages of plant-associated astro-like viruses sheds light on the emergence of potyviruses

scholarly article by Chris Lauber et al published January 2019 in Virus Research

Dissecting the interferon-induced inhibition of hepatitis C virus replication by using a novel host cell line

artículo científico publicado en 2005

Divergent roles of autophagy in virus infection

scientific article published on 25 January 2013

Domain 3 of NS5A protein from the hepatitis C virus has intrinsic alpha-helical propensity and is a substrate of cyclophilin A.

artículo científico publicado en 2011

Dynamic oscillation of translation and stress granule formation mark the cellular response to virus infection

artículo científico publicado en 2012

E2 of hepatitis C virus inhibits apoptosis

artículo científico publicado en 2005

ER-shaping atlastin proteins act as central hubs to promote flavivirus replication and virion assembly

artículo científico publicado en 2019

Editorial: An expanded view of viruses.

artículo científico publicado en 2017

Effects of NS2B-NS3 protease and furin inhibition on West Nile and Dengue virus replication

artículo científico publicado en 2017

Efficient hepatitis C virus cell culture system: what a difference the host cell makes

artículo científico publicado en 2005

Efficient rescue of hepatitis C virus RNA replication by trans-complementation with nonstructural protein 5A.

artículo científico publicado en 2005

Efficient trans-Encapsidation of Hepatitis C Virus RNAs into Infectious Virus-Like Particles

artículo científico publicado en 2008

Endoplasmic Reticulum: The Favorite Intracellular Niche for Viral Replication and Assembly

artículo científico publicado en 2016

Enhancement of genotype 1 hepatitis C virus replication by bile acids through FXR.

artículo científico publicado en 2007

Enhancement of hepatitis C virus RNA replication by cell culture-adaptive mutations

artículo científico publicado en 2001

Erratum for Roth et al., "Flavivirus Infection Uncouples Translation Suppression from Cellular Stress Responses".

artículo científico publicado en 2017

Erratum: Corrigendum: Production of infectious hepatitis C virus in tissue culture from a cloned viral genome

article

Erratum: Tuning a cellular lipid kinase activity adapts hepatitis C virus to replication in cell culture

artículo científico publicado en 2017

Essential Role of Cyclophilin A for Hepatitis C Virus Replication and Virus Production and Possible Link to Polyprotein Cleavage Kinetics

artículo científico publicado en 2009

Essential Role of Domain III of Nonstructural Protein 5A for Hepatitis C Virus Infectious Particle Assembly

artículo científico publicado en 2008

Evidence for novel hepaciviruses in rodents

artículo científico publicado en 2013

Evidence that hepatitis B virus replication in mouse cells is limited by the lack of a host cell dependency factor

artículo científico publicado en 2015

Experimental models to study the immunobiology of hepatitis C virus

artículo científico publicado en 2010

Exploitation of cellular pathways by Dengue virus

artículo científico publicado en 2011

Expression of the P-protein of the human hepatitis B virus in a vaccinia virus system and detection of the nucleocapsid-associated P-gene product by radiolabelling at newly introduced phosphorylation sites ⬇️

artículo científico publicado el 25 de enero de 1992

Expression of the novel hepatitis C virus core+1/ARF protein in the context of JFH1-based replicons

artículo científico publicado en 2015

Factors that determine the antiviral efficacy of HCV-specific CD8(+) T cells ex vivo

artículo científico publicado en 2012

Faculty of 1000 evaluation for A diverse range of gene products are effectors of the type I interferon antiviral response

article

Faculty of 1000 evaluation for A pathogenic picornavirus acquires an envelope by hijacking cellular membranes

Faculty of 1000 evaluation for Antiviral RNA Interference in Mammalian Cells

Faculty of 1000 evaluation for Comparative RNAi screening reveals host factors involved in enterovirus infection of polarized endothelial monolayers

Faculty of 1000 evaluation for Completion of the entire hepatitis C virus life cycle in genetically humanized mice

Faculty of 1000 evaluation for Dephosphorylation of the RNA sensors RIG-I and MDA5 by the phosphatase PP1 is essential for innate immune signaling

Faculty of 1000 evaluation for Ebola Virus VP24 Targets a Unique NLS Binding Site on Karyopherin Alpha 5 to Selectively Compete with Nuclear Import of Phosphorylated STAT1

Faculty of 1000 evaluation for Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets

article

Faculty of 1000 evaluation for Genetic screens in human cells using the CRISPR-Cas9 system

Faculty of 1000 evaluation for Genome-scale CRISPR-Cas9 knockout screening in human cells

Faculty of 1000 evaluation for Influenza Virus Adaptation PB2-627K Modulates Nucleocapsid Inhibition by the Pathogen Sensor RIG-I

Faculty of 1000 evaluation for Influenza virus M2 protein mediates ESCRT-independent membrane scission

Faculty of 1000 evaluation for Innate sensing of HIV-infected cells

article

Faculty of 1000 evaluation for KSHV-initiated notch activation leads to membrane-type-1 matrix metalloproteinase-dependent lymphatic endothelial-to-mesenchymal transition

Faculty of 1000 evaluation for Leukocyte-derived IFN-α/β and epithelial IFN-λ constitute a compartmentalized mucosal defense system that restricts enteric virus infections

Faculty of 1000 evaluation for Mapping a dynamic innate immunity protein interaction network regulating type I interferon production

article

Faculty of 1000 evaluation for Multi-layered stochasticity and paracrine signal propagation shape the type-I interferon response

Faculty of 1000 evaluation for Nucleic Acid-Sensing Toll-like Receptors Are Essential for the Control of Endogenous Retrovirus Viremia and ERV-Induced Tumors

Faculty of 1000 evaluation for Short-range exosomal transfer of viral RNA from infected cells to plasmacytoid dendritic cells triggers innate immunity

Faculty of 1000 evaluation for The RNA Sensor RIG-I Dually Functions as an Innate Sensor and Direct Antiviral Factor for Hepatitis B Virus

Faculty of 1000 evaluation for The membrane-bound transcription factor CREB3L1 is activated in response to virus infection to inhibit proliferation of virus-infected cells

Faculty of 1000 evaluation for Transfer of HBV Genomes Using Low Doses of Adenovirus Vectors Leads to Persistent Infection in Immune Competent Mice

Failure of innate and adaptive immune responses in controlling hepatitis C virus infection

artículo científico publicado en 2012

Flaviviridae Replication Organelles: Oh, What a Tangled Web We Weave

artículo científico publicado en 2015

Flavivirus Infection Uncouples Translation Suppression from Cellular Stress Responses

artículo científico publicado en 2017

From structure to function: new insights into hepatitis C virus RNA replication

artículo científico publicado en 2005

Functional expression, purification, characterization, and membrane reconstitution of non-structural protein 2 from hepatitis C virus

artículo científico publicado en 2015

Functional properties of a monoclonal antibody inhibiting the hepatitis C virus RNA-dependent RNA polymerase

artículo científico publicado en 2001

Generation of T-cell receptors targeting a genetically stable and immunodominant cytotoxic T-lymphocyte epitope within hepatitis C virus non-structural protein 3.

artículo científico publicado en 2011

Genetic Analysis of Sequences in the 3' Nontranslated Region of Hepatitis C Virus That Are Important for RNA Replication

artículo científico publicado en 2002

Geno2pheno[HCV] - A Web-based Interpretation System to Support Hepatitis C Treatment Decisions in the Era of Direct-Acting Antiviral Agents

artículo científico publicado en 2016

Genome packaging of reovirus is mediated by the scaffolding property of the microtubule network

artículo científico publicado en 2017

Genotypic resistance testing of HCV - is there a clinical need?

artículo científico publicado en 2016

Glycine-zipper motifs in hepatitis C virus nonstructural protein 4B are required for the establishment of viral replication organelles

artículo científico publicado en 2017

Going full circle: validation of P-body dispersion in hepatitis C virus-infected patients

artículo científico publicado en 2015

HBV Bypasses the Innate Immune Response and Does not Protect HCV From Antiviral Activity of Interferon.

artículo científico publicado en 2018

HCV modifies EGF signalling and upregulates production of CXCR2 ligands: role in inflammation and antiviral immune response.

artículo científico publicado en 2018

HCV proteins increase expression of heme oxygenase-1 (HO-1) and decrease expression of Bach1 in human hepatoma cells

artículo científico publicado en 2006

Hepatitis B and C virus coinfection: a novel model system reveals the absence of direct viral interference

artículo científico publicado en 2009

Hepatitis B virus with antigenically altered hepatitis B surface antigen is selected by high-dose hepatitis B immune globulin after liver transplantation

artículo científico publicado en 1998

Hepatitis C Virus Activates a Neuregulin-Driven Circuit to Modify Surface Expression of Growth Factor Receptors of the ErbB Family

artículo científico publicado en 2016

Hepatitis C Virus NS5A Protein Is a Substrate for the Peptidyl-prolyl cis/trans Isomerase Activity of Cyclophilins A and B

artículo científico publicado en 2009

Hepatitis C Virus p7 Protein Is Crucial for Assembly and Release of Infectious Virions

artículo científico publicado en 2007

Hepatitis C Virus-From Discovery to Cure: The 2016 Lasker-DeBakey Clinical Medical Research Award

artículo científico publicado en 2016

Hepatitis C virus NS2/3 processing is required for NS3 stability and viral RNA replication

artículo científico publicado en 2005

Hepatitis C virus RNA replication and assembly: living on the fat of the land

artículo científico publicado en 2014

Hepatitis C virus RNA replication is resistant to tumour necrosis factor-alpha

artículo científico publicado en 2003

Hepatitis C virus and host cell lipids: an intimate connection

artículo científico publicado en 2011

Hepatitis C virus core triggers apoptosis in liver cells by inducing ER stress and ER calcium depletion

artículo científico publicado en 2005

Hepatitis C virus core+1/ARF protein decreases hepcidin transcription through an AP1 binding site.

artículo científico publicado en 2013

Hepatitis C virus escape from the interferon regulatory factor 3 pathway by a passive and active evasion strategy

artículo científico publicado en 2007

Hepatitis C virus molecular clones and their replication capacity in vivo and in cell culture

artículo científico publicado en 2007

Hepatitis C virus molecular clones: from cDNA to infectious virus particles in cell culture

artículo científico publicado en 2006

Hepatitis C virus replication cycle

scientific article published on June 2010

Hepatitis C virus replication depends on endosomal cholesterol homeostasis

artículo científico publicado en 2017

Hepatitis C virus replicons volume 3 and 4.

artículo científico publicado en 2012

Hepatitis C virus replicons: dinosaurs still in business?

artículo científico publicado en 2009

Hepatitis C virus replicons: potential role for drug development

artículo científico publicado en 2002

Hepatitis C virus-induced natural killer cell proliferation involves monocyte-derived cells and the OX40/OX40L axis

artículo científico publicado en 2017

Hepatitis C virus-replicating hepatocytes induce fibrogenic activation of hepatic stellate cells.

artículo científico publicado en 2005

Hepatitis C: a mouse at the end of the tunnel

artículo científico publicado en 2013

Hepatitis D virus replication is sensed by MDA5 and induces IFN-β/λ responses in hepatocytes.

artículo científico publicado en 2018

Hepatitis viruses in the XXI century

Heterologous Src homology 4 domains support membrane anchoring and biological activity of HIV-1 Nef

artículo científico publicado en 2014

High density lipoprotein inhibits hepatitis C virus-neutralizing antibodies by stimulating cell entry via activation of the scavenger receptor BI.

artículo científico publicado en 2006

High plasma level of nucleocapsid-free envelope glycoprotein-positive lipoproteins in hepatitis C patients

artículo científico publicado en 2012

High-throughput RNA interference screens integrative analysis: Towards a comprehensive understanding of the virus-host interplay.

artículo científico publicado en 2013

High-throughput screening using dengue virus reporter genomes

artículo científico publicado en 2013

Host factor prioritization for pan-viral genetic perturbation screens using random intercept models and network propagation

artículo científico publicado en 2020

Host-directed therapies for bacterial and viral infections.

artículo científico publicado en 2017

ID: 105

scholarly article by Silke Bender published in November 2015

ID: 219

scholarly article by Joschka Willemsen published in November 2015

Identification and characterization of amphiphysin II as a novel cellular interaction partner of the hepatitis C virus NS5A protein

artículo científico publicado en 2003

Identification of Determinants Involved in Initiation of Hepatitis C Virus RNA Synthesis by Using Intergenotypic Replicase Chimeras

artículo científico publicado en 2007

Identification of HNRNPK as regulator of hepatitis C virus particle production

artículo científico publicado en 2015

Identification of Interleukin1β as an Amplifier of Interferon alpha-induced Antiviral Responses

artículo científico publicado en 2020

Identification of terfenadine as an inhibitor of human CD81-receptor HCV-E2 interaction: synthesis and structure optimization

artículo científico publicado en 2008

Identification of the Hepatitis C Virus RNA Replication Complex in Huh-7 Cells Harboring Subgenomic Replicons

artículo científico publicado en 2003

Identification of type I and type II interferon-induced effectors controlling hepatitis C virus replication.

artículo científico publicado en 2012

Immune-mediated effects targeting hepatitis C virus in a syngeneic replicon cell transplantation mouse model.

artículo científico publicado en 2017

In Vitro Replication Models

In vitro models for hepatitis C.

artículo científico publicado en 2002

In vitro studies on the activation of the hepatitis C virus NS3 proteinase by the NS4A cofactor.

artículo científico publicado en 1996

Inhibition of HCV replication by cyclophilin antagonists is linked to replication fitness and occurs by inhibition of membranous web formation

artículo científico publicado en 2014

Inhibition of Hepatitis C virus by nucleic acid-based antiviral approaches

Inhibition of hepatitis C virus RNA translation by antisense bile acid conjugated phosphorothioate modified oligodeoxynucleotides (ODN).

artículo científico publicado en 2012

Inhibition of hepatitis C virus gene expression by adenoviral vectors encoding antisense RNA in vitro and in vivo

artículo científico publicado en 2010

Interferon type I gene expression in chronic hepatitis C.

artículo científico publicado en 2004

Interferon-alpha inhibits hepatitis C virus subgenomic RNA replication by an MxA-independent pathway

artículo científico publicado en 2001

Interferon-gamma inhibits replication of subgenomic and genomic hepatitis C virus RNAs

artículo científico publicado en 2002

Interferon-induced degradation of the persistent hepatitis B virus cccDNA form depends on ISG20

artículo científico publicado en 2021

Interferon-inducible cholesterol-25-hydroxylase restricts hepatitis C virus replication through blockage of membranous web formation

artículo científico publicado en 2015

Interleukin-32: a new proinflammatory cytokine involved in hepatitis C virus-related liver inflammation and fibrosis

artículo científico publicado en 2011

Investigation of NS3 Protease Resistance-Associated Variants and Phenotypes for the Prediction of Treatment Response to HCV Triple Therapy

artículo científico publicado en 2016

Investigation of a role for lysine residues in non-structural proteins 2 and 2/3 of the hepatitis C virus for their degradation and virus assembly

artículo científico publicado en 2009

Kissing-loop interaction in the 3' end of the hepatitis C virus genome essential for RNA replication

artículo científico publicado en 2005

Live Cell Analysis and Mathematical Modeling Identify Determinants of Attenuation of Dengue Virus 2'-O-Methylation Mutant

scientific article (publication date: December 2015)

Loss of viral fitness and cross-recognition by CD8+ T cells limit HCV escape from a protective HLA-B27–restricted human immune response

artículo científico publicado en 2009

Low oxygen tension enhances hepatitis C virus replication.

artículo científico publicado en 2012

MAP-kinase regulated cytosolic phospholipase A2 activity is essential for production of infectious hepatitis C virus particles

artículo científico publicado en 2012

Male offspring born to mildly ZIKV-infected mice are at risk of developing neurocognitive disorders in adulthood

artículo científico publicado en 2018

Matrix conditions and KLF2-dependent induction of heme oxygenase-1 modulate inhibition of HCV replication by fluvastatin

artículo científico publicado en 2014

Maturation of secreted HCV particles by incorporation of secreted ApoE protects from antibodies by enhancing infectivity.

artículo científico publicado en 2017

Mechanisms governing hepadnaviral nucleocapsid assembly.

artículo científico publicado en 1993

Membrane alterations induced by nonstructural proteins of human norovirus.

artículo científico publicado en 2017

Membrane association of the RNA-dependent RNA polymerase is essential for hepatitis C virus RNA replication

artículo científico publicado en 2004

Membrane undulation induced by NS4A of Dengue virus: a molecular dynamics simulation study

artículo científico publicado en 2013

Membranous replication factories induced by plus-strand RNA viruses

artículo científico publicado en 2014

Modulation of hepatitis C virus NS5A hyperphosphorylation by nonstructural proteins NS3, NS4A, and NS4B

artículo científico publicado en 1999

Molecular aspects of Dengue virus replication

artículo científico publicado en 2008

Molecular mechanism of signal perception and integration by the innate immune sensor retinoic acid-inducible gene-I (RIG-I).

artículo científico publicado en 2011

Molecular mechanisms of hepatitis C virus (HCV) replication - implications for the development of antiviral drugs

artículo científico publicado en 2011

Morphological and biochemical characterization of the membranous hepatitis C virus replication compartment

artículo científico publicado en 2013

Mouse hepatic cells support assembly of infectious hepatitis C virus particles

artículo científico publicado en 2011

Mouse-Specific Residues of Claudin-1 Limit Hepatitis C Virus Genotype 2a Infection in a Human Hepatocyte Cell Line

artículo científico publicado en 2010

Mutational analysis of hepatitis C virus nonstructural protein 5A: potential role of differential phosphorylation in RNA replication and identification of a genetically flexible domain.

artículo científico publicado en 2005

Mutations in Hepatitis C Virus RNAs Conferring Cell Culture Adaptation

artículo científico publicado en 2001

Mutations that alter use of hepatitis C virus cell entry factors mediate escape from neutralizing antibodies

artículo científico publicado en 2012

Mutations that permit efficient replication of hepatitis C virus RNA in Huh-7 cells prevent productive replication in chimpanzees

artículo científico publicado en 2002

NS4B self-interaction through conserved C-terminal elements is required for the establishment of functional hepatitis C virus replication complexes

artículo científico publicado en 2011

NS5A Domain 1 and Polyprotein Cleavage Kinetics Are Critical for Induction of Double-Membrane Vesicles Associated with Hepatitis C Virus Replication

artículo científico publicado en 2015

Neutralizing host responses in hepatitis C virus infection target viral entry at postbinding steps and membrane fusion.

artículo científico publicado en 2008

New insights into structure and replication of the hepatitis C virus and clinical implications

scientific article published on 19 October 2010

New targets for antiviral therapy of chronic hepatitis C.

artículo científico

Nonstructural 3/4A protease of hepatitis C virus activates epithelial growth factor-induced signal transduction by cleavage of the T-cell protein tyrosine phosphatase

artículo científico publicado en 2009

Nonstructural protein 3 of the hepatitis C virus encodes a serine-type proteinase required for cleavage at the NS3/4 and NS4/5 junctions

artículo científico publicado en 1993

Normalizing for individual cell population context in the analysis of high-content cellular screens

artículo científico publicado en 2011

Novel dengue virus NS2B/NS3 protease inhibitors

artículo científico publicado en 2014

Novel indole–flutimide heterocycles with activity against influenza PA endonuclease and hepatitis C virus

Novel insights into hepatitis C virus replication and persistence

artículo científico publicado en 2004

Novel non-heteroarylpyrimidine (HAP) capsid assembly modifiers have a different mode of action from HAPs in vitro

artículo científico publicado en 2018

Novel nucleoside analogues targeting HCV replication through an NS5A-dependent inhibition mechanism.

artículo científico publicado en 2017

Nuclear localization of dengue virus nonstructural protein 5 does not strictly correlate with efficient viral RNA replication and inhibition of type I interferon signaling

artículo científico publicado en 2013

O.067 Hepatitis C virus: Virology, immunology, natural history, treatment

scholarly article by Ralf Bartenschlager published in January 2006

O.137 HDL inhibits neutralisation by HCV antibodies via a ternary interaction with the scavenger receptor BI

O.171 HDL inhibits HCV neutralisation by CD81-NOB antibodies by stimulating cell entry through activation of the scavenger receptor BI

On the history of hepatitis C virus cell culture systems

artículo científico publicado en 2013

Optimization of Substrate-Analogue Furin Inhibitors

artículo científico publicado en 2017

Overall Structural Model of NS5A Protein from Hepatitis C Virus and Modulation by Mutations Confering Resistance of Virus Replication to Cyclosporin A.

artículo científico publicado en 2017

P0676 : Clearance of persistent hepatitis c virus infection using a monoclonal antibody specific for tight junction protein claudin-1

Paradoxical role of antibodies in dengue virus infections: considerations for prophylactic vaccine development

artículo científico publicado en 2015

Peptide-Boronic Acid Inhibitors of Flaviviral Proteases: Medicinal Chemistry and Structural Biology

artículo científico publicado en 2016

Perilipin discerns chronic from acute hepatocellular steatosis

artículo científico publicado en 2013

Persistence of HCV in quiescent hepatic cells under conditions of an interferon-induced antiviral response

artículo científico publicado en 2012

Persistent and transient replication of full-length hepatitis C virus genomes in cell culture

artículo científico publicado en 2002

Persistent intracellular pathogens

artículo científico publicado en 2012

Phenylalanine and Phenylglycine Analogues as Arginine Mimetics in Dengue Protease Inhibitors

artículo científico publicado en 2015

Phosphorylation-Dependent Feedback Inhibition of RIG-I by DAPK1 Identified by Kinome-wide siRNA Screening

artículo científico publicado en 2017

Processing pathways of the hepatitis C virus proteins.

artículo científico publicado en 1996

Prodrug Activation by a Viral Protease: Evaluating Combretastatin Peptide Hybrids To Selectively Target Infected Cells

scientific article published on 18 July 2019

Production of Infectious Genotype 1b Virus Particles in Cell Culture and Impairment by Replication Enhancing Mutations

artículo científico publicado en 2009

Production of infectious hepatitis C virus in primary cultures of human adult hepatocytes

artículo científico publicado en 2010

Production of infectious hepatitis C virus in tissue culture from a cloned viral genome

artículo científico publicado en 2005

Production of infectious hepatitis C virus particles in three-dimensional cultures of the cell line carrying the genome-length dicistronic viral RNA of genotype 1b.

artículo científico publicado en 2006

Promotion of hepatocellular carcinoma by hepatitis C virus

artículo científico publicado en 2012

Proton-Detected Solid-State NMR of the Cell-Free Synthesized α-Helical Transmembrane Protein NS4B from Hepatitis C Virus

scientific article published on 18 December 2019

Quantitative Analysis of the Hepatitis C Virus Replication Complex

artículo científico publicado en 2005

RACK1 mediates rewiring of intracellular networks induced by hepatitis C virus infection

scientific article published on 16 September 2019

Reconstitution of the entire hepatitis C virus life cycle in nonhepatic cells.

artículo científico publicado en 2012

Reconstructing signaling pathways from RNAi data using probabilistic Boolean threshold networks

artículo científico publicado en 2009

Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment

artículo científico publicado en 2011

Relation between viral fitness and immune escape within the hepatitis C virus protease

artículo científico publicado en 2006

Reovirus intermediate subviral particles constitute a strategy to infect intestinal epithelial cells by exploiting TGF-β dependent pro-survival signaling.

artículo científico publicado en 2016

Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line

artículo científico publicado en 1999

Replication of the hepatitis C virus

artículo científico publicado en 2000

Replication of the hepatitis C virus in cell culture

artículo científico publicado en 2003

Replication vesicles are load- and choke-points in the hepatitis C virus lifecycle

artículo científico publicado en 2013

Revisiting dengue virus-host cell interaction: new insights into molecular and cellular virology

artículo científico

Ribavirin Antagonizes the In Vitro Anti-Hepatitis C Virus Activity of 2'-C-Methylcytidine, the Active Component of Valopicitabine

artículo científico publicado en 2006

Robust RNAi enhancement via human Argonaute-2 overexpression from plasmids, viral vectors and cell lines

artículo científico publicado en 2013

Role of RNA Structures in Genome Terminal Sequences of the Hepatitis C Virus for Replication and Assembly

artículo científico publicado en 2009

Role of annexin A2 in the production of infectious hepatitis C virus particles

artículo científico publicado en 2010

Role of the Hepatitis C Virus Core+1 Open Reading Frame and Core cis-Acting RNA Elements in Viral RNA Translation and Replication

artículo científico publicado en 2008

SARS-CoV-2 infection induces a pro-inflammatory cytokine response through cGAS-STING and NF-κB

artículo científico publicado en 2022

SARS-CoV-2 infection remodels the host protein thermal stability landscape

artículo científico publicado en 2021

SARS-CoV-2 structure and replication characterized by in situ cryo-electron tomography

scientific article published on 18 November 2020

Scavenger receptor class B type I is a key host factor for hepatitis C virus infection required for an entry step closely linked to CD81.

artículo científico publicado en 2007

Secretion of Hepatitis C Virus Envelope Glycoproteins Depends on Assembly of Apolipoprotein B Positive Lipoproteins

artículo científico publicado en 2009

Secretion of Hepatitis C Virus Replication Intermediates Reduces Activation of Toll-Like Receptor 3 in Hepatocytes.

artículo científico publicado en 2018

Selective stimulation of hepatitis C virus and pestivirus NS5B RNA polymerase activity by GTP.

artículo científico publicado en 1999

Semen inhibits Zika virus infection of cells and tissues from the anogenital region.

artículo científico publicado en 2018

Sequences in the 5' nontranslated region of hepatitis C virus required for RNA replication.

artículo científico publicado en 2001

Serum versus intrahepatic HCV RNA and liver histology

artículo científico publicado en 2002

Single-cell-based image analysis of high-throughput cell array screens for quantification of viral infection

artículo científico publicado en 2009

Soraphen A: A broad-spectrum antiviral natural product with potent anti-hepatitis C virus activity

artículo científico publicado en 2015

Strategies to inhibit entry of HBV and HDV into hepatocytes.

artículo científico publicado en 2014

Structural and Functional Characterization of Nonstructural Protein 2 for Its Role in Hepatitis C Virus Assembly

artículo científico publicado en 2008

Structural and Functional Properties of the Hepatitis C Virus p7 Viroporin

artículo científico publicado en 2015

Structural and Functional Studies of Nonstructural Protein 2 of the Hepatitis C Virus Reveal Its Key Role as Organizer of Virion Assembly

artículo científico publicado en 2010

Structure and function of the membrane anchor domain of hepatitis C virus nonstructural protein 5A.

artículo científico publicado en 2004

Structures and distributions of SARS-CoV-2 spike proteins on intact virions

scientific article published on 17 August 2020

Subcellular localization and membrane topology of the Dengue virus type 2 Non-structural protein 4B.

artículo científico publicado en 2006

Sustained delivery of siRNAs targeting viral infection by cell-degradable multilayered polyelectrolyte films

artículo científico publicado en 2008

Synthesis and biological evaluation of α-ketoamides as inhibitors of the Dengue virus protease with antiviral activity in cell-culture

artículo científico publicado en 2011

Synthesis, Biological Evaluation, and Molecular Docking of Combretastatin and Colchicine Derivatives and their hCE1-Activated Prodrugs as Antiviral Agents

Synthesis, Biological Evaluation, and Molecular Docking of Combretastatin and Colchicine Derivatives and their hCE1-Activated Prodrugs as Antiviral Agents

scholarly article by Michael Richter et al published 25 January 2019 in ChemMedChem

TALEN/CRISPR-mediated engineering of a promoterless anti-viral RNAi hairpin into an endogenous miRNA locus

artículo científico publicado en 2016

TCR-redirected human T cells inhibit hepatitis C virus replication: hepatotoxic potential is linked to antigen specificity and functional avidity

artículo científico publicado en 2012

TLR3 Activation by Zika Virus Stimulates Inflammatory Cytokine Production Which Dampens the Antiviral Response Induced by RIG-I-Like Receptors

artículo científico publicado en 2021

Targeting of hepatitis C virus core protein to mitochondria through a novel C-terminal localization motif

artículo científico publicado en 2004

Targets for antiviral therapy of hepatitis C.

artículo científico publicado en 2014

The FDA-Approved Drug Cobicistat Synergizes with Remdesivir To Inhibit SARS-CoV-2 Replication <i>In Vitro</i> and Decreases Viral Titers and Disease Progression in Syrian Hamsters

artículo científico publicado en 2022

The Hepatitis C Virus RNA 3'-Untranslated Region Strongly Enhances Translation Directed by the Internal Ribosome Entry Site

artículo científico publicado en 2006

The Level of CD81 Cell Surface Expression Is a Key Determinant for Productive Entry of Hepatitis C Virus into Host Cells

artículo científico publicado en 2007

The Role of Tissue Oxygen Tension in Dengue Virus Replication.

artículo científico publicado en 2018

The face of future hepatitis C antiviral drug development: recent biological and virologic advances and their translation to drug development and clinical practice

artículo científico publicado en 2005

The heme oxygenase 1 product biliverdin interferes with hepatitis C virus replication by increasing antiviral interferon response

artículo científico publicado en 2010

The hepatitis C virus RNA-dependent RNA polymerase membrane insertion sequence is a transmembrane segment

artículo científico publicado en 2002

The hepatitis C virus replicon system: from basic research to clinical application

artículo científico publicado en 2005

The interactomes of influenza virus NS1 and NS2 proteins identify new host factors and provide insights for ADAR1 playing a supportive role in virus replication

scientific journal article

The lipid droplet binding domain of hepatitis C virus core protein is a major determinant for efficient virus assembly

artículo científico publicado en 2007

The lipid droplet is an important organelle for hepatitis C virus production

artículo científico publicado en 2007

The lipid kinase phosphatidylinositol-4 kinase III alpha regulates the phosphorylation status of hepatitis C virus NS5A

artículo científico publicado en 2013

The lysine methyltransferase SMYD3 interacts with hepatitis C virus NS5A and is a negative regulator of viral particle production

artículo científico publicado en 2014

The molecular and structural basis of advanced antiviral therapy for hepatitis C virus infection

artículo científico publicado en 2013

The non-immunosuppressive cyclosporin DEBIO-025 is a potent inhibitor of hepatitis C virus replication in vitro

artículo científico publicado en 2006

The non-structural protein 4A of dengue virus is an integral membrane protein inducing membrane alterations in a 2K-regulated manner

artículo científico publicado en 2007

The predominant species of nonstructural protein 4B in hepatitis C virus-replicating cells is not palmitoylated

artículo científico publicado en 2015

The quest for host targets to combat dengue virus infections

artículo científico publicado en 2016

Thiazolidinone-peptide hybrids as dengue virus protease inhibitors with antiviral activity in cell culture

artículo científico publicado en 2013

Three-dimensional architecture and biogenesis of membrane structures associated with hepatitis C virus replication

artículo científico publicado en 2012

Three-dimensional architecture of tick-borne encephalitis virus replication sites and trafficking of the replicated RNA.

artículo científico publicado en 2013

Tissue culture and animal models for hepatitis C virus

artículo científico publicado en 2003

Towards structural studies of self-assembled subviral particles: combining cell-free expression with 100 kHz MAS NMR.

artículo científico publicado en 2018

Tuning a cellular lipid kinase activity adapts hepatitis C virus to replication in cell culture.

artículo científico publicado en 2016

Type I and type II interferon responses in two human liver cell lines (Huh-7 and HuH6).

artículo científico publicado en 2015

Ultrastructural Characterization of Zika Virus Replication Factories

artículo científico publicado en 2017

Unexpected host range of hepatitis C virus replicons.

artículo científico publicado en 2004

Viral Infection at High Magnification: 3D Electron Microscopy Methods to Analyze the Architecture of Infected Cells

artículo científico publicado en 2015

Viral and Cellular Determinants of Hepatitis C Virus RNA Replication in Cell Culture

artículo científico publicado en 2003

Viral immune modulators perturb the human molecular network by common and unique strategies

artículo científico publicado en 2012

Wheat germ cell-free expression: Two detergents with a low critical micelle concentration allow for production of soluble HCV membrane proteins

artículo científico publicado en 2014

c-Src is required for complex formation between the hepatitis C virus-encoded proteins NS5A and NS5B: a prerequisite for replication

artículo científico publicado en 2011

euHCVdb: the European hepatitis C virus database

artículo científico publicado en 2007

mRNAs biotinylated within the 5' cap and protected against decapping: new tools to capture RNA-protein complexes

scientific article published on 05 November 2018

miRNA-130a targets ATG2B and DICER1 to inhibit autophagy and trigger killing of chronic lymphocytic leukemia cells

artículo científico publicado en 2012

Dominio Público Uruguay está sostenido por:

Acerca de Dominio Público Uruguay

Ayuda