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Lista de obras de Laura van 't Veer

2q36.3 is associated with prognosis for oestrogen receptor-negative breast cancer patients treated with chemotherapy

artículo científico publicado en 2014

70-Gene Signature as an Aid to Treatment Decisions in Early-Stage Breast Cancer

artículo científico publicado en 2016

A breast cancer gene signature for indolent disease

artículo científico publicado en 2017

A cell proliferation signature is a marker of extremely poor outcome in a subpopulation of breast cancer patients

artículo científico publicado en 2005

A common coding variant in CASP8 is associated with breast cancer risk

article

A comprehensive analysis of prognostic signatures reveals the high predictive capacity of the proliferation, immune response and RNA splicing modules in breast cancer ⬇️

artículo científico publicado en 2008

A gene-expression signature as a predictor of survival in breast cancer

artículo científico publicado en 2002

A phase 1b study of the Akt-inhibitor MK-2206 in combination with weekly paclitaxel and trastuzumab in patients with advanced HER2-amplified solid tumor malignancies.

artículo científico publicado en 2016

A protocol for building and evaluating predictors of disease state based on microarray data

artículo científico publicado en 2005

ATBF1 and NQO1 as candidate targets for allelic loss at chromosome arm 16q in breast cancer: absence of somatic ATBF1 mutations and no role for the C609T NQO1 polymorphism

artículo científico publicado en 2008

Abstract 3362: Factors driving industry participation in the collaborative I-SPY2 platform trial

scholarly article

Accuracy of the online prognostication tools PREDICT and Adjuvant! for early-stage breast cancer patients younger than 50 years.

artículo científico publicado en 2017

Adaptive Randomization of Neratinib in Early Breast Cancer

artículo científico publicado en 2016

Adaptive Randomization of Veliparib-Carboplatin Treatment in Breast Cancer

artículo científico publicado en 2016

An Atlas of the Human Kinome Reveals the Mutational Landscape Underlying Dysregulated Phosphorylation Cascades in Cancer.

artículo científico publicado en 2016

An information-theoretic analysis of genetics, gender and age in cancer patients

artículo científico publicado en 2008

Analysis of the MammaPrint breast cancer assay in a predominantly postmenopausal cohort

artículo científico publicado en 2008

Annexin A1 regulates TGF-beta signaling and promotes metastasis formation of basal-like breast cancer cells

artículo científico publicado en 2010

Are ATM mutations 7271T-->G and IVS10-6T-->G really high-risk breast cancer-susceptibility alleles?

artículo científico publicado en 2004

Assessment of Long-term Distant Recurrence-Free Survival Associated With Tamoxifen Therapy in Postmenopausal Patients With Luminal A or Luminal B Breast Cancer

scientific article published on 08 August 2019

Association of Event-Free and Distant Recurrence-Free Survival With Individual-Level Pathologic Complete Response in Neoadjuvant Treatment of Stages 2 and 3 Breast Cancer: Three-Year Follow-up Analysis for the I-SPY2 Adaptively Randomized Clinical T

scientific article published on 23 July 2020

Association of the germline TP53 R72P and MDM2 SNP309 variants with breast cancer survival in specific breast tumor subgroups.

artículo científico publicado en 2011

Associations of a Breast Cancer Polygenic Risk Score With Tumor Characteristics and Survival

scholarly article

Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies

artículo científico publicado en 2010

Associations of common variants at 1p11.2 and 14q24.1 (RAD51L1) with breast cancer risk and heterogeneity by tumor subtype: findings from the Breast Cancer Association Consortium

artículo científico publicado en 2011

Bilateral prophylactic mastectomy reduces breast cancer risk in BRCA1 and BRCA2 mutation carriers: the PROSE Study Group

artículo científico publicado en 2004

Biological functions of the genes in the mammaprint breast cancer profile reflect the hallmarks of cancer.

artículo científico publicado en 2010

Body mass index and breast cancer survival: a Mendelian randomization analysis

artículo científico publicado en 2017

Breast Cancer Screening in the Precision Medicine Era: Risk-Based Screening in a Population-Based Trial.

artículo científico publicado en 2017

Breast Cancer Survival and Tumor Characteristics in Premenopausal Women Carrying theCHEK2*1100delCGermline Mutation

artículo científico publicado en 2006

Breast Cancer Survival of BRCA1/BRCA2 Mutation Carriers in a Hospital-Based Cohort of Young Women.

artículo científico publicado en 2017

Breast cancer risk and 6q22.33: combined results from Breast Cancer Association Consortium and Consortium of Investigators on Modifiers of BRCA1/2

artículo científico publicado en 2012

CHEK2*1100delC heterozygosity in women with breast cancer associated with early death, breast cancer-specific death, and increased risk of a second breast cancer

artículo científico publicado en 2012

Calibration and discriminatory accuracy of prognosis calculation for breast cancer with the online Adjuvant! program: a hospital-based retrospective cohort study.

artículo científico publicado en 2009

Clinical application of the 70-gene profile: the MINDACT trial

artículo científico publicado en 2008

Clinical utility of the 70-gene MammaPrint profile in a Japanese population.

artículo científico publicado en 2010

Co-expression modules identified from published immune signatures reveal five distinct immune subtypes in breast cancer

artículo científico publicado en 2016

Combined effects of single nucleotide polymorphisms TP53 R72P and MDM2 SNP309, and p53 expression on survival of breast cancer patients

artículo científico publicado en 2009

Comparison of gene expression profiles predicting progression in breast cancer patients treated with tamoxifen

artículo científico publicado en 2008

Complex landscapes of somatic rearrangement in human breast cancer genomes

artículo científico publicado en 2009

Comprehensive transcriptomic analysis of cell lines as models of primary tumors across 22 tumor types

scientific article published on 08 August 2019

Concordance among gene-expression-based predictors for breast cancer

artículo científico publicado en 2006

Confirmation of 5p12 as a susceptibility locus for progesterone-receptor-positive, lower grade breast cancer

artículo científico publicado en 2011

Controlling technical variation amongst 6693 patient microarrays of the randomized MINDACT trial

artículo científico publicado en 2020

Converting a breast cancer microarray signature into a high-throughput diagnostic test.

artículo científico publicado en 2006

Correction: Cost-Effectiveness Of Treatment Strategies for BRAF-Mutated Metastatic Melanoma

artículo científico publicado en 2015

Corrigendum: Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells

artículo científico publicado en 2016

Cost-effectiveness analysis of the 70-gene signature compared with clinical assessment in breast cancer based on a randomised controlled trial

artículo científico publicado en 2020

Cost-effectiveness of treatment strategies for BRAF-mutated metastatic melanoma

artículo científico publicado en 2014

Cross-validated Cox regression on microarray gene expression data

artículo científico publicado en 2006

Current Landscape of Breast Cancer Imaging and Potential Quantitative Imaging Markers of Response in ER-Positive Breast Cancers Treated with Neoadjuvant Therapy

scientific article published on 09 June 2020

DNA repair deficiency biomarkers and the 70-gene ultra-high risk signature as predictors of veliparib/carboplatin response in the I-SPY 2 breast cancer trial

artículo científico publicado en 2017

Detection of circulating breast tumor cells by differential expression of marker genes

scientific article published on 01 June 2002

Discordant assessment of tumor biomarkers by histopathological and molecular assays in the EORTC randomized controlled 10041/BIG 03-04 MINDACT trial breast cancer : Intratumoral heterogeneity and DCIS or normal tissue components are unlikely to be t

artículo científico publicado en 2016

Do MDM2 SNP309 and TP53 R72P interact in breast cancer susceptibility? A large pooled series from the breast cancer association consortium

artículo científico publicado en 2007

Do rectal cancer patients with PIK3CA mutations benefit from preoperative radiotherapy with regard to local recurrences?

artículo científico publicado en 2010

E-cadherin breast tumor expression, risk factors and survival: Pooled analysis of 5,933 cases from 12 studies in the Breast Cancer Association Consortium.

artículo científico publicado en 2018

Effect of Pembrolizumab Plus Neoadjuvant Chemotherapy on Pathologic Complete Response in Women With Early-Stage Breast Cancer: An Analysis of the Ongoing Phase 2 Adaptively Randomized I-SPY2 Trial

artículo científico publicado en 2020

Equivalence of MammaPrint array types in clinical trials and diagnostics

artículo científico publicado en 2016

Erratum to: Modeling precision treatment of breast cancer

artículo científico publicado en 2015

Erratum: Corrigendum: A common coding variant in CASP8 is associated with breast cancer risk

scholarly article published in Nature Genetics

Evaluation of National Comprehensive Cancer Network guideline-based Tool for Risk Assessment for breast and ovarian Cancer (N-TRAC): A patient-reported survey for genetic high-risk assessment for breast and ovarian cancers in women

scientific article published on 21 January 2019

Evaluation of the Dutch BRCA1/2 clinical genetic center referral criteria in an unselected early breast cancer population

artículo científico publicado en 2014

Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation

artículo científico publicado en 2014

Expanded genomic profiling of circulating tumor cells in metastatic breast cancer patients to assess biomarker status and biology over time

artículo científico publicado en 2018

Expression of insulin-like growth factor system components in colorectal tissue and its relation with serum IGF levels

artículo científico publicado en 2008

Expression profiling of circulating tumor cells in metastatic breast cancer

artículo científico publicado en 2014

Expression profiling predicts outcome in breast cancer

artículo científico publicado en 2003

Family history, genetic testing, and clinical risk prediction: pooled analysis of CHEK2 1100delC in 1,828 bilateral breast cancers and 7,030 controls

artículo científico publicado en 2009

Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2.

artículo científico publicado en 2015

Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1.

artículo científico publicado en 2013

Five polymorphisms and breast cancer risk: results from the Breast Cancer Association Consortium

artículo científico publicado en 2009

Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus

artículo científico publicado en 2016

Ganitumab and metformin plus standard neoadjuvant therapy in stage 2/3 breast cancer

artículo científico publicado en 2021

Gene Expression Signature to Improve Prognosis Prediction of Stage II and III Colorectal Cancer

article

Gene co-expression modules as clinically relevant hallmarks of breast cancer diversity

artículo científico publicado en 2014

Gene expression profiles from formalin fixed paraffin embedded breast cancer tissue are largely comparable to fresh frozen matched tissue

artículo científico publicado en 2011

Gene expression profiling predicts clinical outcome of breast cancer

artículo científico publicado en 2002

Gene expression profiling to identify the histogenetic origin of metastatic adenocarcinomas of unknown primary

artículo científico publicado en 2008

Gene signature evaluation as a prognostic tool: challenges in the design of the MINDACT trial

artículo científico publicado en 2006

Genetic variants in TGFβ-1 and PAI-1 as possible risk factors for cardiovascular disease after radiotherapy for breast cancer.

artículo científico publicado en 2011

Genetic variation at CYP3A is associated with age at menarche and breast cancer risk: a case-control study

artículo científico publicado en 2014

Genetic variation in mitotic regulatory pathway genes is associated with breast tumor grade

artículo científico publicado en 2014

Genome-wide association studies identify four ER negative-specific breast cancer risk loci

artículo científico publicado en 2013

Glutamine sensitivity analysis identifies the xCT antiporter as a common triple-negative breast tumor therapeutic target

artículo científico publicado en 2013

Heterogeneous drug penetrance of veliparib and carboplatin measured in triple negative breast tumors

artículo científico publicado en 2017

High-throughput automated scoring of Ki67 in breast cancer tissue microarrays from the Breast Cancer Association Consortium

artículo científico publicado en 2016

Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk

artículo científico publicado en 2014

Impact of Age at Primary Breast Cancer on Contralateral Breast Cancer Risk in BRCA1/2 Mutation Carriers

artículo científico publicado en 2015

Impact of mammographic screening on the detection of good and poor prognosis breast cancers

artículo científico publicado en 2011

Individualization of therapy using Mammaprint: from development to the MINDACT Trial

artículo científico publicado en 2007

Insulin-like growth factor (IGF)-system mRNA quantities in normal and tumor breast tissue of women with sporadic and familial breast cancer risk

artículo científico publicado en 2004

Intratumor Heterogeneity of the Estrogen Receptor and the Long-term Risk of Fatal Breast Cancer

artículo científico publicado en 2018

Landscape of somatic mutations in 560 breast cancer whole-genome sequences

artículo científico publicado en 2016

Large-scale genotyping identifies 41 new loci associated with breast cancer risk

artículo científico publicado en 2013

Laura van 't Veer, PhD: bringing tumor gene profiles into the clinic. Interview

artículo científico publicado en 2004

Lobular histology and response to neoadjuvant chemotherapy in invasive breast cancer.

artículo científico publicado en 2012

Locoregional Breast Cancer Recurrence in the European Organisation for Research and Treatment of Cancer 10041/BIG 03-04 MINDACT Trial: Analysis of Risk Factors Including the 70-Gene Signature

scholarly article

Low penetrance breast cancer susceptibility loci are associated with specific breast tumor subtypes: findings from the Breast Cancer Association Consortium

artículo científico publicado en 2011

Lycopene supplementation elevates circulating insulin-like growth factor binding protein-1 and -2 concentrations in persons at greater risk of colorectal cancer

artículo científico publicado en 2007

MK-2206 and Standard Neoadjuvant Chemotherapy Improves Response in Patients With Human Epidermal Growth Factor Receptor 2-Positive and/or Hormone Receptor-Negative Breast Cancers in the I-SPY 2 Trial

artículo científico publicado en 2019

MammaPrint 70-gene profile quantifies the likelihood of recurrence for early breast cancer

artículo científico publicado en 2009

MammaPrint and BluePrint Molecular Diagnostics Using Targeted RNA Next-Generation Sequencing Technology

artículo científico publicado en 2019

MammaPrint molecular diagnostics on formalin-fixed, paraffin-embedded tissue

artículo científico publicado en 2013

Mammosphere-derived gene set predicts outcome in patients with ER-positive breast cancer

artículo científico publicado en 2009

Mapping phospho-catalytic dependencies of therapy-resistant tumours reveals actionable vulnerabilities

scientific article published on 03 June 2019

Mechanism of action biomarkers predicting response to AKT inhibition in the I-SPY 2 breast cancer trial

artículo científico publicado en 2020

Metastatic potential of T1 breast cancer can be predicted by the 70-gene MammaPrint signature

artículo científico publicado en 2010

MicroRNA related polymorphisms and breast cancer risk

artículo científico publicado en 2014

Missense variants in ATM in 26,101 breast cancer cases and 29,842 controls

artículo científico publicado en 2010

Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes

artículo científico publicado en 2014

Molecular Portraits and 70-Gene Prognosis Signature Are Preserved throughout the Metastatic Process of Breast Cancer

article

Molecular classification of breast carcinomas by comparative genomic hybridization: a specific somatic genetic profile for BRCA1 tumors

artículo científico publicado en 2002

Multi-gene panel testing for hereditary cancer predisposition in unsolved high-risk breast and ovarian cancer patients

artículo científico publicado en 2017

Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin

artículo científico publicado en 2014

New Horizons in Advocacy Engaged Physical Sciences and Oncology Research.

artículo científico publicado en 2018

No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer.

artículo científico publicado en 2015

No effect of red clover-derived isoflavone intervention on the insulin-like growth factor system in women at increased risk of colorectal cancer

artículo científico publicado en 2008

PIK3CA Mutations Predict Local Recurrences in Rectal Cancer Patients

artículo científico publicado en 2009

PKA-induced phosphorylation of ERα at serine 305 and high PAK1 levels is associated with sensitivity to tamoxifen in ER-positive breast cancer

artículo científico publicado en 2010

PRoBE the cloud toolkit: finding the best biomarkers of drug response within a breast cancer clinical trial

artículo científico publicado en 2021

Pathologic complete response predicts recurrence-free survival more effectively by cancer subset: results from the I-SPY 1 TRIAL--CALGB 150007/150012, ACRIN 6657.

artículo científico publicado en 2012

Performance characteristics of the MammaPrint®breast cancer diagnostic gene signature

article

Physical activity and the risk of breast cancer in BRCA1/2 mutation carriers

artículo científico publicado en 2009

Potential for bias in studies on efficacy of prophylactic surgery for BRCA1 and BRCA2 mutation

artículo científico publicado en 2003

Prediction and clinical utility of a contralateral breast cancer risk model

scientific article published on 17 December 2019

Prediction of contralateral breast cancer: external validation of risk calculators in 20 international cohorts

scientific article published on 11 April 2020

Presence of ATM protein and residual kinase activity correlates with the phenotype in ataxia-telangiectasia: A genotype-phenotype study ⬇️

artículo científico publicado el 25 de enero de 2012

Prognostic Impact of Breast-Conserving Therapy Versus Mastectomy of BRCA1/2 Mutation Carriers Compared With Noncarriers in a Consecutive Series of Young Breast Cancer Patients

scientific article published on 01 August 2019

Prognostic Value of MammaPrint® in Invasive Lobular Breast Cancer

artículo científico publicado en 2016

Publisher Correction: Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation.

artículo científico publicado en 2018

Recent advances in metastasis research

artículo científico publicado en 2008

Regulatory aspects of genetic research with residual human tissue: effective and efficient data coding

artículo científico publicado en 2009

Reliable and effective diagnostics are keys to accelerating personalized cancer medicine and transforming cancer care: a policy statement from the american association for cancer research

artículo científico publicado en 2014

Road map to metastasis

artículo científico publicado en 2003

Robust interlaboratory reproducibility of a gene expression signature measurement consistent with the needs of a new generation of diagnostic tools

artículo científico publicado en 2007

Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival

artículo científico publicado en 2005

Serial expression analysis of breast tumors during neoadjuvant chemotherapy reveals changes in cell cycle and immune pathways associated with recurrence and response

artículo científico publicado en 2015

Somatic mutations reveal asymmetric cellular dynamics in the early human embryo

artículo científico publicado en 2017

Specific genomic aberrations in primary colorectal cancer are associated with liver metastases

artículo científico publicado en 2010

Standard Anthracycline Based Versus Docetaxel-Capecitabine in Early High Clinical and/or Genomic Risk Breast Cancer in the EORTC 10041/BIG 3-04 MINDACT Phase III Trial

artículo científico publicado en 2020

Synchronous Detection of Circulating Tumor Cells in Blood and Disseminated Tumor Cells in Bone Marrow Predicts Adverse Outcome in Early Breast Cancer

artículo científico publicado en 2019

TP53 germline mutation testing in 180 families suspected of Li-Fraumeni syndrome: mutation detection rate and relative frequency of cancers in different familial phenotypes

artículo científico publicado en 2010

Tamoxifen therapy benefit for patients with 70-gene signature high and low risk

artículo científico publicado en 2017

Targetable mechanisms driving immunoevasion of persistent senescent cells link chemotherapy-resistant cancer to aging

artículo científico publicado en 2019

Ten-year follow-up of the observational RASTER study, prospective evaluation of the 70-gene signature in ER-positive, HER2-negative, node-negative, early breast cancer

scholarly article

The 70-gene prognosis-signature predicts disease outcome in breast cancer patients with 1–3 positive lymph nodes in an independent validation study

article

The 70-gene signature as a response predictor for neoadjuvant chemotherapy in breast cancer

artículo científico publicado en 2009

The Athena Breast Health Network: developing a rapid learning system in breast cancer prevention, screening, treatment, and care ⬇️

artículo científico publicado el 26 de julio de 2013

The BRCA1ness signature is associated significantly with response to PARP inhibitor treatment versus control in the I-SPY 2 randomized neoadjuvant setting.

artículo científico publicado en 2017

The MINDACT trial: the first prospective clinical validation of a genomic tool

artículo científico publicado en 2007

The Neoadjuvant Model Is Still the Future for Drug Development in Breast Cancer

artículo científico publicado en 2015

The San Francisco Cancer Initiative: A Community Effort To Reduce The Population Burden Of Cancer

artículo científico publicado en 2018

The insulin-like growth factor system in cancer prevention: potential of dietary intervention strategies.

artículo científico publicado en 2005

The predictive value of the 70-gene signature for adjuvant chemotherapy in early breast cancer.

artículo científico publicado en 2010

The role of genetic breast cancer susceptibility variants as prognostic factors

artículo científico publicado en 2012

The single-nucleotide polymorphism 309 in the MDM2 gene contributes to the Li-Fraumeni syndrome and related phenotypes

artículo científico publicado en 2006

Tumor Drug Penetration Measurements Could Be the Neglected Piece of the Personalized Cancer Treatment Puzzle

scientific article published on 06 October 2018

Use of 70-gene signature to predict prognosis of patients with node-negative breast cancer: a prospective community-based feasibility study (RASTER).

artículo científico publicado en 2007

Use of Molecular Tools to Identify Patients With Indolent Breast Cancers With Ultralow Risk Over 2 Decades.

artículo científico publicado en 2017

Validation and clinical utility of a 70-gene prognostic signature for women with node-negative breast cancer

artículo científico publicado en 2006

Worse breast cancer prognosis of BRCA1/BRCA2 mutation carriers: what's the evidence? A systematic review with meta-analysis

artículo científico publicado en 2015

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