Lista de obras - Pilar Santisteban - Dominio Público Uruguay

A Novel Role for the Tumor Suppressor Gene ITF2 in Tumorigenesis and Chemotherapy Response

artículo científico publicado en 2020

A novel role for the tumor suppressor gene ITF2 in lung tumorigenesis through the action of Wnt signaling pathway

article

A perspective view of sodium iodide symporter research and its clinical implications

artículo científico publicado en 2006

A positive feedback loop between DICER1 and differentiation transcription factors is important for thyroid tumorigenesis

artículo científico publicado en 2020

ADAR1-mediated RNA editing is a novel oncogenic process in thyroid cancer and regulates miR-200 activity

artículo científico publicado en 2020

Abstracts

artículo científico publicado en 2017

Activation of the GLP-1 Receptor by Liraglutide Increases ACE2 Expression, Reversing Right Ventricle Hypertrophy, and Improving the Production of SP-A and SP-B in the Lungs of Type 1 Diabetes Rats

artículo científico publicado en 2015

Amino acid composition of proteins extracted from endemic goiter glands

article

An epistatic interaction between the PAX8 and STK17B genes in papillary thyroid cancer susceptibility.

artículo científico publicado en 2013

An oncogenic role for microRNA-146b in the thyroid

artículo científico publicado en 2018

Association Study of 69 Genes in the Ret Pathway Identifies Low-penetrance Loci in Sporadic Medullary Thyroid Carcinoma

article

Association between BRAF V600E mutation and mortality in patients with papillary thyroid cancer

artículo científico publicado en 2013

Association between BRAF V600E mutation and recurrence of papillary thyroid cancer.

artículo científico publicado en 2014

BRAF V600E Confers Male Sex Disease-Specific Mortality Risk in Patients With Papillary Thyroid Cancer

artículo científico publicado en 2018

BRAF V600E Mutation-Assisted Risk Stratification of Solitary Intrathyroidal Papillary Thyroid Cancer for Precision Treatment

artículo científico publicado en 2017

BRAF V600E Status Sharply Differentiates Lymph Node Metastasis-associated Mortality Risk in Papillary Thyroid Cancer

artículo científico publicado en 2021

BRAF V600E status may facilitate decision-making on active surveillance of low-risk papillary thyroid microcarcinoma

scientific article published on 29 November 2019

Bacterial lipopolysaccharide stimulates the thyrotropin-dependent thyroglobulin gene expression at the transcriptional level by involving the transcription factors thyroid transcription factor-1 and paired box domain transcription factor 8

scientific journal article

Correction: An Epistatic Interaction between the PAX8 and STK17B Genes in Papillary Thyroid Cancer Susceptibility

artículo científico publicado en 2013

DARPP-32 (dopamine and 3',5'-cyclic adenosine monophosphate-regulated neuronal phosphoprotein) is essential for the maintenance of thyroid differentiation

artículo científico publicado en 2005

DARPP-32 is required for MAPK/ERK signaling in thyroid cells

artículo científico publicado en 2012

DNA methylation signatures identify biologically distinct thyroid cancer subtypes.

artículo científico publicado en 2013

Differential Clinicopathological Risk and Prognosis of Major Papillary Thyroid Cancer Variants.

artículo científico publicado en 2015

DuOx2 Promoter Regulation by Hormones, Transcriptional Factors and the Coactivator TAZ.

artículo científico publicado en 2015

Dynamic expression of Groucho-related genes Grg1 and Grg3 in foregut endoderm and antagonism of differentiation

artículo científico publicado en 2010

ENDOCRINE TUMOURS: Advances in the molecular pathogenesis of thyroid cancer: lessons from the cancer genome

artículo científico publicado en 2016

FOXE1 regulates migration and invasion in thyroid cancer cells and targets ZEB1

scientific article published on 01 March 2020

FOXO1 Controls Thyroid Cell Proliferation in Response to TSH and IGF-I and Is Involved in Thyroid Tumorigenesis ⬇️

artículo científico publicado el 16 de noviembre de 2012

Function of the homeo and paired domain proteins TTF-1 and Pax-8 in thyroid cell proliferation

artículo científico publicado en 1995

Functional Study of a Novel Single Deletion in theTITF1/NKX2.1Homeobox Gene That Produces Congenital Hypothyroidism and Benign Chorea But Not Pulmonary Distress

article

Functional Toll-like Receptor 4 Overexpression in Papillary Thyroid Cancer by MAPK/ERK-induced ETS1 Transcriptional Activity

artículo científico publicado en 2018

Gbetagamma dimers released in response to thyrotropin activate phosphoinositide 3-kinase and regulate gene expression in thyroid cells

artículo científico publicado en 2008

Gene network transitions in embryos depend upon interactions between a pioneer transcription factor and core histones

artículo científico publicado en 2020

Genome-wide analysis of Pax8 binding provides new insights into thyroid functions

artículo científico publicado en 2012

Ha-ras interference with thyroid cell differentiation is associated with a down-regulation of thyroid transcription factor-1 phosphorylation

artículo científico publicado en 1998

Hippo Pathway mediator TAZ acts as a negative regulator of the sodium iodide symporter

Identification of a cis-regulatory element and a thyroid-specific nuclear factor mediating the hormonal regulation of rat thyroid peroxidase promoter activity

artículo científico publicado en 1993

Impaired Gene Expression Due to Iodine Excess in the Development and Differentiation of Endoderm and Thyroid Is Associated with Epigenetic Changes

artículo científico publicado en 2020

Impaired miRNA processing by DICER1 downregulation endows thyroid cancer with increased aggressiveness

Impaired microRNA processing by DICER1 downregulation endows thyroid cancer with increased aggressiveness

scientific article published on 09 April 2019

In Vivo Inhibition of MicroRNA to Decrease Tumor Growth in Mice

scientific article published on 23 August 2019

Industry-Sponsored Satellite Symposia.

artículo científico publicado en 2017

Insulin and insulin-like growth factor I regulate a thyroid-specific nuclear protein that binds to the thyroglobulin promoter

artículo científico publicado en 1992

Insulin regulation of malic enzyme gene expression in rat liver: evidence for nuclear proteins that bind to two putative insulin response elements

scientific article published on 01 October 1994

Insulin-induced Early Growth Response Gene (Egr-1) Mediates a Short Term Repression of Rat Malic Enzyme Gene Transcription

scientific article published in Journal of Biological Chemistry

Introduction of p53 induces cell-cycle arrest in p53-deficient human medullary-thyroid-carcinoma cells

artículo científico publicado en 1997

Key signaling pathways in thyroid cancer

artículo científico publicado en 2017

Lung hypoplasia caused by nitrofen is mediated by down-regulation of thyroid transcription factor TTF-1

artículo científico publicado en 1999

Malic enzyme gene expression in differentiating brown adipocytes: regulation by insulin and triiodothyronine

artículo científico publicado en 1993

MicroRNA deep-sequencing reveals master regulators of follicular and papillary thyroid tumors.

artículo científico publicado en 2015

MicroRNA-146b promotes PI3K/AKT pathway hyperactivation and thyroid cancer progression by targeting PTEN.

artículo científico publicado en 2018

Molecular biology of thyroid cancer initiation.

artículo científico publicado en 2007

NFE2-Related Transcription Factor 2 Coordinates Antioxidant Defense with Thyroglobulin Production and Iodination in the Thyroid Gland

scientific article published on 01 June 2018

NIS mediates iodide uptake in the female reproductive tract and is a poor prognostic factor in ovarian cancer

artículo científico publicado en 2014

New insights in thyroid follicular cell biology and its impact in thyroid cancer therapy

artículo científico publicado en 2007

New insights into FoxE1 functions: identification of direct FoxE1 targets in thyroid cells

artículo científico publicado en 2013

Norepinephrine, tri-iodothyronine and insulin upregulate glyceraldehyde-3-phosphate dehydrogenase mRNA during Brown adipocyte differentiation

artículo científico publicado en 1999

PI3K is involved in the IGF-I inhibition of TSH-induced sodium/iodide symporter gene expression

artículo científico publicado en 2002

Patient Age-Associated Mortality Risk Is Differentiated by BRAF V600E Status in Papillary Thyroid Cancer.

artículo científico publicado en 2017

Pax8 controls thyroid follicular polarity through cadherin-16.

artículo científico publicado en 2016

RAS Subcellular Localization Inversely Regulates Thyroid Tumor Growth and Dissemination

scientific article published on 10 September 2020

Re-evaluation of some factors affecting the stability of rat thyroglobulin

artículo científico publicado en 1980

Regulation of Foxe1 by Thyrotropin and Transforming Growth Factor Beta Depends on the Interplay Between Thyroid-Specific, CREB and SMAD Transcription Factors

scientific article published on 13 February 2019

Regulation of thyroid oxidative state by thioredoxin reductase has a crucial role in thyroid responses to iodide excess

artículo científico publicado en 2011

Regulators of the RAS-ERK pathway as therapeutic targets in thyroid cancer

artículo científico publicado en 2019

RhoA activation promotes transformation and loss of thyroid cell differentiation interfering with thyroid transcription factor-1 activity

artículo científico publicado en 2002

Role of iodide metabolism in physiology and cancer

artículo científico publicado en 2018

Role of the wnt pathway in thyroid cancer

artículo científico

Selenium Increases Thyroid-Stimulating Hormone-Induced Sodium/Iodide Symporter Expression Through Thioredoxin/Apurinic/Apyrimidinic Endonuclease 1-Dependent Regulation of Paired Box 8 Binding Activity.

artículo científico publicado en 2015

Somatostatin interferes with thyrotropin-induced G1-S transition mediated by cAMP-dependent protein kinase and phosphatidylinositol 3-kinase. Involvement of RhoA and cyclin E x cyclin-dependent kinase 2 complexes

artículo científico publicado en 2000

Somatostatin is expressed in FRTL-5 thyroid cells and prevents thyrotropin-mediated down-regulation of the cyclin-dependent kinase inhibitor p27kip1.

artículo científico publicado en 1999

Subcellular localization of iodinated thyroid tubulin

artículo científico publicado en 1989

TAZ/WWTR1 mediates the pulmonary effects of NKX2-1 mutations in Brain-Lung-Thyroid syndrome.

artículo científico publicado en 2017

TSH signalling and cancer.

artículo científico publicado en 2007

TSH-activated signaling pathways in thyroid tumorigenesis

artículo científico publicado en 2003

Telomerase-driven expression of the sodium iodide symporter (NIS) for in vivo radioiodide treatment of cancer: a new broad-spectrum NIS-mediated antitumor approach

artículo científico publicado en 2011

The BRAFV600E oncogene induces transforming growth factor beta secretion leading to sodium iodide symporter repression and increased malignancy in thyroid cancer

artículo científico publicado en 2009

The Interaction between the Forkhead Thyroid Transcription Factor TTF-2 and the Constitutive Factor CTF/NF-1 Is Required for Efficient Hormonal Regulation of the Thyroperoxidase Gene Transcription

artículo científico publicado en 1999

The MDM2 oncoprotein promotes apoptosis in p53-deficient human medullary thyroid carcinoma cells

artículo científico publicado en 2000

The Prognostic Value of Tumor Multifocality in Clinical Outcomes of Papillary Thyroid Cancer

artículo científico publicado en 2017

The forkhead factor FoxE1 binds to the thyroperoxidase promoter during thyroid cell differentiation and modifies compacted chromatin structure

artículo científico publicado en 2007

The functional interaction between the paired domain transcription factor Pax8 and Smad3 is involved in transforming growth factor-beta repression of the sodium/iodide symporter gene

artículo científico publicado en 2003

The miR-146b-3p/PAX8/NIS Regulatory Circuit Modulates the Differentiation Phenotype and Function of Thyroid Cells during Carcinogenesis

artículo científico publicado en 2015

The oncogene BRAFV600E is associated with a high risk of recurrence and less differentiated papillary thyroid carcinoma due to the impairment of Na+/I− targeting to the membrane

scientific article published on 01 March 2006

The small GTP-binding protein, Rhes, regulates signal transduction from G protein-coupled receptors

artículo científico publicado en 2004

The variant rs1867277 in FOXE1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors

artículo científico publicado en 2009

Thyroid cancer GWAS identifies 10q26.12 and 6q14.1 as novel susceptibility loci and reveals genetic heterogeneity among populations

artículo científico publicado en 2015

Thyroid development and effect on the nervous system

artículo científico publicado en 2005

Thyroid transcription factors in development, differentiation and disease

artículo científico publicado en 2015

Thyroid-specific gene expression in the multi-step process of thyroid carcinogenesis

artículo científico publicado en 1999

Thyroid-stimulating hormone/cAMP-mediated proliferation in thyrocytes

artículo científico publicado en 2008

Transcriptional Control of the Forkhead Thyroid Transcription Factor TTF-2 by Thyrotropin, Insulin, and Insulin-like Growth Factor I

artículo científico publicado en 1997

Transcriptional repressor DREAM interacts with thyroid transcription factor-1 and regulates thyroglobulin gene expression

artículo científico publicado en 2004

Transportador de yodo (NIS) y su aplicación diagnóstica y terapéutica en diferentes enfermedades

artículo científico publicado en 2008

Wnt-independent role of β-catenin in thyroid cell proliferation and differentiation

artículo científico publicado en 2014

mRNA circularization by METTL3-eIF3h enhances translation and promotes oncogenesis

artículo científico publicado en 2018

miRNA-Directed Regulation of the Main Signaling Pathways in Thyroid Cancer

artículo científico publicado en 2019

β-catenin signaling is required for RAS-driven thyroid cancer through PI3K activation.

artículo científico publicado en 2016

Lista de obras de Pilar Santisteban

A Novel Role for the Tumor Suppressor Gene ITF2 in Tumorigenesis and Chemotherapy Response

A novel role for the tumor suppressor gene ITF2 in lung tumorigenesis through the action of Wnt signaling pathway

A perspective view of sodium iodide symporter research and its clinical implications

A positive feedback loop between DICER1 and differentiation transcription factors is important for thyroid tumorigenesis

ADAR1-mediated RNA editing is a novel oncogenic process in thyroid cancer and regulates miR-200 activity

Abstracts

Activation of the GLP-1 Receptor by Liraglutide Increases ACE2 Expression, Reversing Right Ventricle Hypertrophy, and Improving the Production of SP-A and SP-B in the Lungs of Type 1 Diabetes Rats

Amino acid composition of proteins extracted from endemic goiter glands

An epistatic interaction between the PAX8 and STK17B genes in papillary thyroid cancer susceptibility.

An oncogenic role for microRNA-146b in the thyroid

Association Study of 69 Genes in the Ret Pathway Identifies Low-penetrance Loci in Sporadic Medullary Thyroid Carcinoma

Association between BRAF V600E mutation and mortality in patients with papillary thyroid cancer

Association between BRAF V600E mutation and recurrence of papillary thyroid cancer.

BRAF V600E Confers Male Sex Disease-Specific Mortality Risk in Patients With Papillary Thyroid Cancer

BRAF V600E Mutation-Assisted Risk Stratification of Solitary Intrathyroidal Papillary Thyroid Cancer for Precision Treatment

BRAF V600E Status Sharply Differentiates Lymph Node Metastasis-associated Mortality Risk in Papillary Thyroid Cancer

BRAF V600E status may facilitate decision-making on active surveillance of low-risk papillary thyroid microcarcinoma

Bacterial lipopolysaccharide stimulates the thyrotropin-dependent thyroglobulin gene expression at the transcriptional level by involving the transcription factors thyroid transcription factor-1 and paired box domain transcription factor 8

Correction: An Epistatic Interaction between the PAX8 and STK17B Genes in Papillary Thyroid Cancer Susceptibility

DARPP-32 (dopamine and 3',5'-cyclic adenosine monophosphate-regulated neuronal phosphoprotein) is essential for the maintenance of thyroid differentiation

DARPP-32 is required for MAPK/ERK signaling in thyroid cells

DNA methylation signatures identify biologically distinct thyroid cancer subtypes.

Differential Clinicopathological Risk and Prognosis of Major Papillary Thyroid Cancer Variants.

DuOx2 Promoter Regulation by Hormones, Transcriptional Factors and the Coactivator TAZ.

Dynamic expression of Groucho-related genes Grg1 and Grg3 in foregut endoderm and antagonism of differentiation

ENDOCRINE TUMOURS: Advances in the molecular pathogenesis of thyroid cancer: lessons from the cancer genome

FOXE1 regulates migration and invasion in thyroid cancer cells and targets ZEB1

FOXO1 Controls Thyroid Cell Proliferation in Response to TSH and IGF-I and Is Involved in Thyroid Tumorigenesis ⬇️

Function of the homeo and paired domain proteins TTF-1 and Pax-8 in thyroid cell proliferation

Functional Study of a Novel Single Deletion in theTITF1/NKX2.1Homeobox Gene That Produces Congenital Hypothyroidism and Benign Chorea But Not Pulmonary Distress

Functional Toll-like Receptor 4 Overexpression in Papillary Thyroid Cancer by MAPK/ERK-induced ETS1 Transcriptional Activity

Gbetagamma dimers released in response to thyrotropin activate phosphoinositide 3-kinase and regulate gene expression in thyroid cells

Gene network transitions in embryos depend upon interactions between a pioneer transcription factor and core histones

Genome-wide analysis of Pax8 binding provides new insights into thyroid functions

Ha-ras interference with thyroid cell differentiation is associated with a down-regulation of thyroid transcription factor-1 phosphorylation

Hippo Pathway mediator TAZ acts as a negative regulator of the sodium iodide symporter

Identification of a cis-regulatory element and a thyroid-specific nuclear factor mediating the hormonal regulation of rat thyroid peroxidase promoter activity

Impaired Gene Expression Due to Iodine Excess in the Development and Differentiation of Endoderm and Thyroid Is Associated with Epigenetic Changes

Impaired miRNA processing by DICER1 downregulation endows thyroid cancer with increased aggressiveness

Impaired microRNA processing by DICER1 downregulation endows thyroid cancer with increased aggressiveness

In Vivo Inhibition of MicroRNA to Decrease Tumor Growth in Mice

Industry-Sponsored Satellite Symposia.

Insulin and insulin-like growth factor I regulate a thyroid-specific nuclear protein that binds to the thyroglobulin promoter

Insulin regulation of malic enzyme gene expression in rat liver: evidence for nuclear proteins that bind to two putative insulin response elements

Insulin-induced Early Growth Response Gene (Egr-1) Mediates a Short Term Repression of Rat Malic Enzyme Gene Transcription

Introduction of p53 induces cell-cycle arrest in p53-deficient human medullary-thyroid-carcinoma cells

Key signaling pathways in thyroid cancer

Lung hypoplasia caused by nitrofen is mediated by down-regulation of thyroid transcription factor TTF-1

Malic enzyme gene expression in differentiating brown adipocytes: regulation by insulin and triiodothyronine

MicroRNA deep-sequencing reveals master regulators of follicular and papillary thyroid tumors.

MicroRNA-146b promotes PI3K/AKT pathway hyperactivation and thyroid cancer progression by targeting PTEN.

Molecular biology of thyroid cancer initiation.

NFE2-Related Transcription Factor 2 Coordinates Antioxidant Defense with Thyroglobulin Production and Iodination in the Thyroid Gland

NIS mediates iodide uptake in the female reproductive tract and is a poor prognostic factor in ovarian cancer

New insights in thyroid follicular cell biology and its impact in thyroid cancer therapy

New insights into FoxE1 functions: identification of direct FoxE1 targets in thyroid cells

Norepinephrine, tri-iodothyronine and insulin upregulate glyceraldehyde-3-phosphate dehydrogenase mRNA during Brown adipocyte differentiation

PI3K is involved in the IGF-I inhibition of TSH-induced sodium/iodide symporter gene expression

Patient Age-Associated Mortality Risk Is Differentiated by BRAF V600E Status in Papillary Thyroid Cancer.

Pax8 controls thyroid follicular polarity through cadherin-16.

RAS Subcellular Localization Inversely Regulates Thyroid Tumor Growth and Dissemination

Re-evaluation of some factors affecting the stability of rat thyroglobulin

Regulation of Foxe1 by Thyrotropin and Transforming Growth Factor Beta Depends on the Interplay Between Thyroid-Specific, CREB and SMAD Transcription Factors

Regulation of thyroid oxidative state by thioredoxin reductase has a crucial role in thyroid responses to iodide excess

Regulators of the RAS-ERK pathway as therapeutic targets in thyroid cancer

RhoA activation promotes transformation and loss of thyroid cell differentiation interfering with thyroid transcription factor-1 activity

Role of iodide metabolism in physiology and cancer

Role of the wnt pathway in thyroid cancer

Selenium Increases Thyroid-Stimulating Hormone-Induced Sodium/Iodide Symporter Expression Through Thioredoxin/Apurinic/Apyrimidinic Endonuclease 1-Dependent Regulation of Paired Box 8 Binding Activity.

Somatostatin interferes with thyrotropin-induced G1-S transition mediated by cAMP-dependent protein kinase and phosphatidylinositol 3-kinase. Involvement of RhoA and cyclin E x cyclin-dependent kinase 2 complexes

Somatostatin is expressed in FRTL-5 thyroid cells and prevents thyrotropin-mediated down-regulation of the cyclin-dependent kinase inhibitor p27kip1.

Subcellular localization of iodinated thyroid tubulin

TAZ/WWTR1 mediates the pulmonary effects of NKX2-1 mutations in Brain-Lung-Thyroid syndrome.

TSH signalling and cancer.

TSH-activated signaling pathways in thyroid tumorigenesis

Telomerase-driven expression of the sodium iodide symporter (NIS) for in vivo radioiodide treatment of cancer: a new broad-spectrum NIS-mediated antitumor approach

The BRAFV600E oncogene induces transforming growth factor beta secretion leading to sodium iodide symporter repression and increased malignancy in thyroid cancer

The Interaction between the Forkhead Thyroid Transcription Factor TTF-2 and the Constitutive Factor CTF/NF-1 Is Required for Efficient Hormonal Regulation of the Thyroperoxidase Gene Transcription

The MDM2 oncoprotein promotes apoptosis in p53-deficient human medullary thyroid carcinoma cells