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Lista de obras de Thumbi Ndung'u

8th IAS Conference on HIV Pathogenesis, Treatment and Prevention (IAS 2015)

article

A FRESH approach: Combining basic science and social good

artículo científico publicado en 2018

A Novel HIV-1 RNA Testing Intervention to Detect Acute and Prevalent HIV Infection in Young Adults and Reduce HIV Transmission in Kenya: Protocol for a Randomized Controlled Trial

artículo científico publicado en 2020

A PowerPack of SuperScientists: An innovative concept by African scientists to address gender bias and inequity in science

artículo científico publicado en 2023

A PowerPack of SuperScientists: An innovative concept by African scientists to address gender bias and inequity in science

scientific article published in 2022

A high burden of asymptomatic genital tract infections undermines the syndromic management approach among adolescents and young adults in South Africa: implications for HIV prevention efforts

article

A molecular assay for sensitive detection of pathogen-specific T-cells

artículo científico publicado en 2011

A new human immunodeficiency virus type 1 circulating recombinant form from Tanzania

artículo científico publicado en 2001

A35 Viral evolution and innate immune responses during acute HIV-1 infection and their association with disease pathogenesis

artículo científico publicado en 2017

APOBEC3G expression is dysregulated in primary HIV-1 infection and polymorphic variants influence CD4+ T-cell counts and plasma viral load

artículo científico publicado en 2010

Ability of HIV-1 Nef to downregulate CD4 and HLA class I differs among viral subtypes

artículo científico publicado en 2013

Adaptation of HIV-1 to human leukocyte antigen class I

artículo científico publicado en 2009

Additive contribution of HLA class I alleles in the immune control of HIV-1 infection

artículo científico publicado en 2010

Alterations in natural killer cell receptor profiles during HIV type 1 disease progression among chronically infected South African adults

artículo científico publicado en 2010

Amino-acid co-variation in HIV-1 Gag subtype C: HLA-mediated selection pressure and compensatory dynamics

artículo científico publicado en 2010

An HIV-1 Nef genotype that diminishes immune control mediated by protective human leucocyte antigen alleles

artículo científico publicado en 2020

Analysis of Dominant HIV Quasispecies Suggests Independent Viral Evolution Within Spinal Granulomas Coinfected with Mycobacterium tuberculosis and HIV-1 Subtype C.

artículo científico publicado en 2015

Association Between Plasma Antibody Responses and Risk for Cryptococcus-Associated Immune Reconstitution Inflammatory Syndrome

article

Association between injectable progestin-only contraceptives and HIV acquisition and HIV target cell frequency in the female genital tract in South African women: a prospective cohort study

artículo científico publicado en 2015

Association between the cytokine storm, immune cell dynamics, and viral replicative capacity in hyperacute HIV infection

scientific article published on 25 March 2020

Association between virus-specific T-cell responses and plasma viral load in human immunodeficiency virus type 1 subtype C infection

artículo científico publicado en 2003

Association of IL-10-promoter genetic variants with the rate of CD4 T-cell loss, IL-10 plasma levels, and breadth of cytotoxic T-cell lymphocyte response during chronic HIV-1 infection

artículo científico publicado en 2011

Association of TRIM22 with the type 1 interferon response and viral control during primary HIV-1 infection

artículo científico publicado en 2010

Association of interleukin-10 promoter genetic variants with T-cell and B-cell activation in HIV-1 infection

artículo científico publicado en 2012

Association of polymorphisms in the LEDGF/p75 gene (PSIP1) with susceptibility to HIV-1 infection and disease progression

artículo científico publicado en 2011

Augmentation of HIV-specific T cell function by immediate treatment of hyperacute HIV-1 infection

artículo científico publicado en 2019

Biomarkers for Tuberculosis Based on Secreted, Species-Specific, Bacterial Small Molecules

artículo científico publicado en 2015

Broad and persistent Gag-specific CD8+ T-cell responses are associated with viral control but rarely drive viral escape during primary HIV-1 infection

artículo científico publicado en 2015

CD8 T cell response and evolutionary pressure to HIV-1 cryptic epitopes derived from antisense transcription

artículo científico publicado en 2010

CD8+ T Cell Breadth and Ex Vivo Virus Inhibition Capacity Distinguish between Viremic Controllers with and without Protective HLA Class I Alleles

artículo científico publicado en 2016

CD8+ TCR Bias and Immunodominance in HIV-1 Infection

artículo científico publicado en 2015

Case records of the Massachusetts General Hospital. Case 15-2011. A 19-year-old South African woman with headache, fatigue, and vaginal discharge

artículo científico publicado en 2011

Case records of the Massachusetts General Hospital. Case 18-2010. A 7-year-old boy with elevated HIV RNA levels despite antiretroviral medications

artículo científico publicado en 2010

Cellular Architecture of Spinal Granulomas and the Immunological Response in Tuberculosis Patients Coinfected with HIV.

artículo científico publicado en 2017

Central role of reverting mutations in HLA associations with human immunodeficiency virus set point

artículo científico publicado en 2008

Cerebrospinal T-cell responses aid in the diagnosis of tuberculous meningitis in a human immunodeficiency virus- and tuberculosis-endemic population

artículo científico publicado en 2010

Cervicovaginal bacteria are a major modulator of host inflammatory responses in the female genital tract

artículo científico publicado en 2015

Changes in Natural Killer cell activation and function during primary HIV-1 Infection

artículo científico publicado en 2013

Characterization of Nucleoside Reverse Transcriptase Inhibitor-Associated Mutations in the RNase H Region of HIV-1 Subtype C Infected Individuals.

artículo científico publicado en 2017

Characterization of anti-HIV-1 neutralizing and binding antibodies in chronic HIV-1 subtype C infection

artículo científico publicado en 2012

Chemokine levels and chemokine receptor expression in the blood and the cerebrospinal fluid of HIV-infected patients with cryptococcal meningitis and cryptococcosis-associated immune reconstitution inflammatory syndrome

artículo científico publicado en 2013

Clinical and mycological predictors of cryptococcosis-associated immune reconstitution inflammatory syndrome

artículo científico publicado en 2013

Clinical, Virologic, Immunologic Outcomes and Emerging HIV Drug Resistance Patterns in Children and Adolescents in Public ART Care in Zimbabwe

artículo científico publicado en 2015

Clonal expansion of genome-intact HIV-1 in functionally polarized Th1 CD4+ T cells

artículo científico publicado en 2017

Co-infection with Mycobacterium tuberculosis impairs HIV-Specific CD8+ and CD4+ T cell functionality

artículo científico publicado en 2015

Co-operative additive effects between HLA alleles in control of HIV-1

artículo científico publicado en 2012

Comparative utility of cytokine levels and quantitative RD-1-specific T cell responses for rapid immunodiagnosis of tuberculous meningitis

artículo científico publicado en 2011

Comparison of Etests and Vitek 2 ® to broth microdilution for the susceptibility testing of Cryptococcus neoformans

artículo científico publicado en 2014

Comparison of amplicor and GeneXpert MTB/RIF tests for diagnosis of tuberculous meningitis

artículo científico publicado en 2014

Compartmentalization of innate immune responses in the central nervous system during cryptococcal meningitis/HIV coinfection

artículo científico publicado en 2014

Complex Subtype Diversity of HIV-1 Among Drug Users in Major Kenyan Cities

artículo científico publicado en 2017

Construction and analysis of an infectious human Immunodeficiency virus type 1 subtype C molecular clone

artículo científico publicado en 2001

Correction for Ojwach et al., "Pol-Driven Replicative Capacity Impacts Disease Progression in HIV-1 Subtype C Infection"

article

Correction for Thobakgale et al., Impact of HLA in Mother and Child on Disease Progression of Pediatric Human Immunodeficiency Virus Type 1 Infection

artículo científico publicado en 2015

Cryptococcosis-IRIS is associated with lower cryptococcus-specific IFN-γ responses before antiretroviral therapy but not higher T-cell responses during therapy

artículo científico publicado en 2013

Detection and molecular characterisation of group a rotavirus from children in northern Botswana.

artículo científico publicado en 2005

Detection and treatment of Fiebig stage I HIV-1 infection in young at-risk women in South Africa: a prospective cohort study

artículo científico publicado en 2017

Diagnostic Accuracy of the HemoCue Hb 301, STAT-Site MHgb and URIT-12 Point-of-Care Hemoglobin Meters in a Central Laboratory and a Community Based Clinic in Durban, South Africa

artículo científico publicado en 2016

Diagnostic accuracy of quantitative PCR (Xpert MTB/RIF) for tuberculous meningitis in a high burden setting: a prospective study

artículo científico publicado en 2013

Differential Pathogen-Specific Immune Reconstitution in Antiretroviral Therapy-Treated Human Immunodeficiency Virus-Infected Children

scholarly article by Maximilian Muenchhoff et al published 16 April 2019 in Journal of Infectious Diseases

Differential clade-specific HLA-B*3501 association with HIV-1 disease outcome is linked to immunogenicity of a single Gag epitope

artículo científico publicado en 2012

Differential escape patterns within the dominant HLA-B*57:03-restricted HIV Gag epitope reflect distinct clade-specific functional constraints

artículo científico publicado en 2014

Discordant Impact of HLA on Viral Replicative Capacity and Disease Progression in Pediatric and Adult HIV Infection

artículo científico publicado en 2015

Drug resistance and coreceptor usage in HIV type 1 subtype C-infected children initiating or failing highly active antiretroviral therapy in South Africa

artículo científico publicado en 2011

Drug resistance and viral tropism in HIV-1 subtype C-infected patients in KwaZulu-Natal, South Africa: implications for future treatment options

artículo científico publicado en 2011

Drug resistance pattern of HIV type 1 isolates sampled in 2007 from therapy-naive pregnant women in North-Central Nigeria

artículo científico publicado en 2011

Dual HLA B*42 and B*81-reactive T cell receptors recognize more diverse HIV-1 Gag escape variants

artículo científico publicado en 2018

Duffy-null-associated low neutrophil counts influence HIV-1 susceptibility in high-risk South African black women

artículo científico publicado en 2011

Dynamics and frequency of Gag transmitted polymorphisms in Zambia

artículo científico publicado en 2012

Effect of female genital schistosomiasis and anti-schistosomal treatment on monocytes, CD4+ T-cells and CCR5 expression in the female genital tract

artículo científico publicado en 2014

Elevated HLA-A expression impairs HIV control through inhibition of NKG2A-expressing cells

artículo científico publicado en 2018

Elevated tumor necrosis factor-alpha activation of human immunodeficiency virus type 1 subtype C in Southern Africa is associated with an NF-kappaB enhancer gain-of-function

artículo científico publicado en 2000

Enhanced anti-HIV functional activity associated with Gag-specific CD8 T-cell responses ⬇️

artículo científico publicado en 2010

Epigenetic mechanisms, T-cell activation, and CCR5 genetics interact to regulate T-cell expression of CCR5, the major HIV-1 coreceptor

artículo científico publicado en 2015

Evaluation of a synthetic peptide for the detection of anti-Mycobacterium tuberculosis curli pili IgG antibodies in patients with pulmonary tuberculosis.

artículo científico publicado en 2018

Evaluation of the NucliSens EasyQ v2.0 assay in comparison with the Roche Amplicor v1.5 and the Roche CAP/CTM HIV-1 Test v2.0 in quantification of C-clade HIV-1 in plasma

artículo científico publicado en 2014

Evolution of HLA-B*5703 HIV-1 escape mutations in HLA-B*5703-positive individuals and their transmission recipients

artículo científico publicado en 2009

Expanding HIV surveillance to include TB patients in resource-limited settings with a generalized epidemic.

artículo científico publicado en 2009

Exposure to HIV-1-encoded Toll-like receptor 8 ligands enhances monocyte response to microbial encoded Toll-like receptor 2/4 ligands

artículo científico publicado en 2010

Extended high viremics: a substantial fraction of individuals maintain high plasma viral RNA levels after acute HIV-1 subtype C infection

artículo científico publicado en 2011

Frequencies of Circulating Th1-Biased T Follicular Helper Cells in Acute HIV-1 Infection Correlate with the Development of HIV-Specific Antibody Responses and Lower Set Point Viral Load

article

Frequencies of circulating Th1-biased T follicular helper cells in acute HIV-1 infection correlate with the development of HIV-specific antibody responses and lower set point viral load

article

Frequent and strong antibody-mediated NK cell activation to HIV-1 Env in individuals with chronic HIV-1 infection.

artículo científico publicado en 2012

Frequent and strong antibody-mediated natural killer cell activation in response to HIV-1 Env in individuals with chronic HIV-1 infection

artículo científico publicado en 2012

Functional and genetic analysis of coreceptor usage by dualtropic HIV-1 subtype C isolates

artículo científico publicado en 2009

Functional characterization of Vif proteins from HIV-1 infected patients with different APOBEC3G haplotypes

artículo científico publicado en 2016

Gag-protease-mediated replication capacity in HIV-1 subtype C chronic infection: associations with HLA type and clinical parameters

artículo científico publicado en 2010

Genetic characteristics, coreceptor usage potential and evolution of Nigerian HIV-1 subtype G and CRF02_AG isolates

artículo científico publicado en 2011

Genetic determinants of Nef-mediated CD4 and HLA class I down-regulation differences between HIV-1 subtypes B and C.

artículo científico publicado en 2015

HIV Controllers Exhibit Enhanced Frequencies of Major Histocompatibility Complex Class II Tetramer+ Gag-Specific CD4+ T Cells in Chronic Clade C HIV-1 Infection

artículo científico publicado en 2017

HIV Disrupts Human T Cells That Target Mycobacterial Glycolipids

artículo científico publicado en 2015

HIV control through a single nucleotide on the HLA-B locus

artículo científico publicado en 2012

HIV skews the SARS-CoV-2 B cell response towards an extrafollicular maturation pathway

artículo científico publicado en 2022

HIV status alters disease severity and immune cell responses in Beta variant SARS-CoV-2 infection wave

artículo científico publicado en 2021

HIV subtype influences HLA-B*07:02-associated HIV disease outcome

artículo científico publicado en 2013

HIV transmission. Selection bias at the heterosexual HIV-1 transmission bottleneck

artículo científico publicado en 2014

HIV type 1 A/J recombinant with a pronounced pol gene mosaicism

artículo científico publicado en 2000

HIV-1 DNA sequence diversity and evolution during acute subtype C infection

scientific article published on 21 June 2019

HIV-1 evades a gag mutation that abrogates KIR binding and disinhibits NK cells in infected individuals with KIR2DL2+/HLA-C*03: 04+ genotype

artículo científico publicado en 2020

HIV-1 integrase variants retarget viral integration and are associated with disease progression in a chronic infection cohort

artículo científico publicado en 2014

HIV-1 subtype C envelope characteristics associated with divergent rates of chronic disease progression

artículo científico publicado en 2010

HIV-1 subtype C in vitro growth and coreceptor utilization.

artículo científico publicado en 2006

HIV-1 vaccine immunogen design strategies

artículo científico publicado en 2015

HLA Footprints on Human Immunodeficiency Virus Type 1 Are Associated with Interclade Polymorphisms and Intraclade Phylogenetic Clustering

scholarly article by Philippa C Matthews et al published 15 April 2011 in Journal of Virology

HLA class I-driven evolution of human immunodeficiency virus type 1 subtype c proteome: immune escape and viral load

artículo científico publicado en 2008

HLA contributes to immune control of hepatitis B in HIV-positive African adults

article

HLA footprints on human immunodeficiency virus type 1 are associated with interclade polymorphisms and intraclade phylogenetic clustering

artículo científico publicado en 2009

HLA-A is a Predictor of Hepatitis B e Antigen Status in HIV-Positive African Adults

artículo científico publicado en 2015

HLA-A*7401-mediated control of HIV viremia is independent of its linkage disequilibrium with HLA-B*5703

artículo científico publicado en 2011

HLA-B*57 Micropolymorphism shapes HLA allele-specific epitope immunogenicity, selection pressure, and HIV immune control

artículo científico publicado en 2011

HLA-Cw*03-restricted CD8+ T-cell responses targeting the HIV-1 gag major homology region drive virus immune escape and fitness constraints compensated for by intracodon variation

artículo científico publicado en 2010

HLA-specific intracellular epitope processing shapes an immunodominance pattern for HLA-B*57 that is distinct from HLA-B*58:01

artículo científico publicado en 2013

HLArestrictor--a tool for patient-specific predictions of HLA restriction elements and optimal epitopes within peptides

artículo científico publicado en 2010

High expression of CD26 accurately identifies human bacteria-reactive MR1-restricted MAIT cells

artículo científico publicado en 2015

High frequency of transmitted HIV-1 Gag HLA class I-driven immune escape variants but minimal immune selection over the first year of clade C infection

artículo científico publicado en 2015

High-Frequency, Functional HIV-Specific T-Follicular Helper and Regulatory Cells Are Present Within Germinal Centers in Children but Not Adults

article

Highly active antiretroviral therapy started during pregnancy or postpartum suppresses HIV-1 RNA, but not DNA, in breast milk

artículo científico publicado en 2005

Human TRIM5alpha expression levels and reduced susceptibility to HIV-1 infection

artículo científico publicado en 2009

Human immunodeficiency virus type 1 subtype C molecular phylogeny: consensus sequence for an AIDS vaccine design?

artículo científico publicado en 2002

Identification of human immunodeficiency virus type 1 subtype C Gag-, Tat-, Rev-, and Nef-specific elispot-based cytotoxic T-lymphocyte responses for AIDS vaccine design

artículo científico publicado en 2001

Immunodominant HIV-1-specific HLA-B- and HLA-C-restricted CD8+ T cells do not differ in polyfunctionality

artículo científico publicado en 2010

Immunohistological characterization of spinal TB granulomas from HIV-negative and -positive patients

artículo científico publicado en 2013

Impact of HLA Allele-KIR Pairs on HIV Clinical Outcome in South Africa

scientific article published in 2019

Impact of HLA in mother and child on disease progression of pediatric human immunodeficiency virus type 1 infection

artículo científico publicado en 2009

Impact of HLA-B*81-associated mutations in HIV-1 Gag on viral replication capacity

artículo científico publicado en 2012

Impact of HLA-driven HIV adaptation on virulence in populations of high HIV seroprevalence

artículo científico publicado en 2014

Impact of blood processing variations on natural killer cell frequency, activation, chemokine receptor expression and function

artículo científico publicado en 2011

Impact of pre-adapted HIV transmission.

artículo científico publicado en 2016

Impact of select immunologic and virologic biomarkers on CD4 cell count decrease in patients with chronic HIV-1 subtype C infection: results from Sinikithemba Cohort, Durban, South Africa

scientific article published on September 2009

Impairment of CD1d-restricted natural killer T cells in chronic HIV type 1 clade C infection

artículo científico publicado en 2010

Implementation of couples' voluntary HIV counseling and testing services in Durban, South Africa

artículo científico publicado en 2015

Increased Regulatory T-Cell Activity and Enhanced T-Cell Homeostatic Signaling in Slow Progressing HIV-infected Children

article

Individuals with HIV-1 Subtype C Infection and Cryptococcal Meningitis Exhibit Viral Genetic Intermixing of HIV-1 Between Plasma and Cerebrospinal Fluid and a High Prevalence of CXCR4-Using Variants.

artículo científico publicado en 2018

Infant feeding practices were not associated with breast milk HIV-1 RNA levels in a randomized clinical trial in Botswana

artículo científico publicado en 2012

Infectious simian/human immunodeficiency virus with human immunodeficiency virus type 1 subtype C from an African isolate: rhesus macaque model.

artículo científico publicado en 2001

Influence of Gag-protease-mediated replication capacity on disease progression in individuals recently infected with HIV-1 subtype C.

artículo científico publicado en 2011

Influence of variations in CCL3L1 and CCR5 on tuberculosis in a northwestern Colombian population

artículo científico publicado en 2011

Innate Lymphoid Cells Are Depleted Irreversibly during Acute HIV-1 Infection in the Absence of Viral Suppression.

artículo científico publicado en 2016

Interactive association of proviral load and IFN-gamma-secreting T cell responses in HIV-1C infection

artículo científico publicado en 2006

Interleukin-10 promoter polymorphisms influence HIV-1 susceptibility and primary HIV-1 pathogenesis

artículo científico publicado en 2009

Intersubtype differences in the effect of a rare p24 gag mutation on HIV-1 replicative fitness

artículo científico publicado en 2012

KIR-HLA footprints and NK cell-mediated recognition of HIV-1.

artículo científico publicado en 2012

Killer-cell Immunoglobulin-like Receptor (KIR) gene profiles modify HIV disease course, not HIV acquisition in South African women.

artículo científico publicado en 2016

Knowledge of HIV serodiscordance, transmission, and prevention among couples in Durban, South Africa

artículo científico publicado en 2015

Lack of Duffy antigen receptor for chemokines: no influence on HIV disease progression in an African treatment-naive population

artículo científico publicado en 2009

Lack of association between HLA class II alleles and in vitro replication capacities of recombinant viruses encoding HIV-1 subtype C Gag-protease from chronically infected individuals

artículo científico publicado en 2011

Lactobacillus-Deficient Cervicovaginal Bacterial Communities Are Associated with Increased HIV Acquisition in Young South African Women

artículo científico publicado en 2017

Latent and Active Tuberculosis Infection Increase Immune Activation in Individuals Co-Infected with HIV

artículo científico publicado en 2015

Limited Sequence Variation and Similar Phenotypic Characteristics of HIV-1 Subtype C Gag Variants Derived From the Reservoir and Pre-Therapy Plasma

artículo científico publicado en 2022

Limited immunogenicity of HIV CD8+ T-cell epitopes in acute Clade C virus infection

artículo científico publicado en 2011

Longitudinal assessment of HIV-1-specific T-cell responses generated during acute subtype C HIV-1 infection and associations with viral set point

artículo científico publicado en 2012

Low Replication Capacity Virus Is Preferentially Transmitted In Mother-To-Child-Transmission But Not In Adult-To-Adult-Transmission Of HIV-1

article

Low levels of peripheral CD161++CD8+ mucosal associated invariant T (MAIT) cells are found in HIV and HIV/TB co-infection

artículo científico publicado en 2013

Lower Viral Loads and Slower CD4+ T-Cell Count Decline in MRKAd5 HIV-1 Vaccinees Expressing Disease-Susceptible HLA-B*58:02

artículo científico publicado en 2016

Magnitude and Kinetics of CD8+ T Cell Activation during Hyperacute HIV Infection Impact Viral Set Point

artículo científico publicado en 2015

Magnitude and frequency of cytotoxic T-lymphocyte responses: identification of immunodominant regions of human immunodeficiency virus type 1 subtype C.

artículo científico publicado en 2002

Major TCR Repertoire Perturbation by Immunodominant HLA-B44:03-Restricted CMV-Specific T Cells

Major histocompatibility complex class II (HLA-DRB and -DQB) allele frequencies in Botswana: association with human immunodeficiency virus type 1 infection

artículo científico publicado en 2005

Malnutrition in HIV-Infected Children Is an Indicator of Severe Disease with an Impaired Response to Antiretroviral Therapy

artículo científico publicado en 2017

Managing the demand for global health education

artículo científico publicado en 2011

Maternal single-dose nevirapine versus placebo as part of an antiretroviral strategy to prevent mother-to-child HIV transmission in Botswana

artículo científico publicado en 2006

Modelling and in vitro testing of the HIV-1 Nef fitness landscape

artículo científico publicado en 2019

Molecular cloning and biological characterization of full-length HIV-1 subtype C from Botswana

artículo científico publicado en 2000

Molecular cloning and phylogenetic analysis of human immunodeficiency virus type 1 subtype C: a set of 23 full-length clones from Botswana

artículo científico publicado en 1999

Mosaic HIV-1 Gag antigens can be processed and presented to human HIV-specific CD8+ T cells

artículo científico publicado en 2011

Mother-to-Child HIV Transmission Bottleneck Selects for Consensus Virus with Lower Gag-Protease-Driven Replication Capacity

artículo científico publicado en 2017

Natural killer cell function in women at high risk for HIV acquisition: insights from a microbicide trial

artículo científico publicado en 2012

Nef-mediated down-regulation of CD4 and HLA class I in HIV-1 subtype C infection: association with disease progression and influence of immune pressure

artículo científico publicado en 2014

Nef-mediated inhibition of NFAT following TCR stimulation differs between HIV-1 subtypes

scientific article published on 21 February 2019

Nef-specific CD8+ T cell responses contribute to HIV-1 immune control

artículo científico publicado en 2013

Neutralizing and non-neutralizing antibody responses in HIV-1 subtype C chronically infected patients with divergent rates of disease progression.

artículo científico publicado en 2012

Neutrophil Effector Functions Are Not Impaired in Duffy Antigen Receptor for Chemokines (DARC)-Null Black South Africans

Neutrophil counts in persons of African origin

artículo científico publicado en 2014

No evidence for selection of HIV-1 with enhanced gag-protease or Nef function among breakthrough infections in the CAPRISA 004 tenofovir microbicide trial

artículo científico publicado en 2013

Nonprogressing HIV-infected children share fundamental immunological features of nonpathogenic SIV infection

artículo científico publicado en 2016

Nucleoside reverse transcriptase inhibitor resistance mutations associated with first-line stavudine-containing antiretroviral therapy: programmatic implications for countries phasing out stavudine

artículo científico publicado en 2013

On HIV diversity

artículo científico

P07-02. Cytotoxic T lymphocyte-mediated immune responses in HIV-1 clade C infected mother-child pairs.

artículo científico publicado en 2009

P07-07. Non-progressive paediatric HIV infection is associated with virus attenuation and increase in CD8+ specific T cell responses over time.

artículo científico publicado en 2009

P09-09. Impact of immune-driven sequence variation in HIV-1 subtype C Gag-Protease on viral fitness and disease progression

article

PARV4 prevalence, phylogeny, immunology and coinfection with HIV, HBV and HCV in a multicentre African cohort

artículo científico publicado en 2017

Paediatric non-progression following grandmother-to-child HIV transmission

artículo científico publicado en 2016

Plasma But Not Cerebrospinal Fluid Interleukin 7 and Interleukin 5 Levels Pre-Antiretroviral Therapy Commencement Predict Cryptococcosis-Associated Immune Reconstitution Inflammatory Syndrome

artículo científico publicado en 2017

Plasma CXCL13 but Not B Cell Frequencies in Acute HIV Infection Predicts Emergence of Cross-Neutralizing Antibodies

artículo científico publicado en 2017

Pol-Driven Replicative Capacity Impacts Disease Progression in HIV-1 Subtype C Infection

artículo científico publicado en 2018

Possession of HLA class II DRB1*1303 associates with reduced viral loads in chronic HIV-1 clade C and B infection

artículo científico publicado en 2011

Preservation HIV-1-specific IFNγ+ CD4+ T-cell responses in breakthrough infections after exposure to tenofovir gel in the CAPRISA 004 microbicide trial

artículo científico publicado en 2012

Prevalence and Characteristics of Hepatitis B Virus (HBV) Coinfection among HIV-Positive Women in South Africa and Botswana

artículo científico publicado en 2015

Prevalence and seasonality of common viral respiratory pathogens, including Cytomegalovirus in children, between 0-5 years of age in KwaZulu-Natal, an HIV endemic province in South Africa

article

Progression to AIDS in South Africa is associated with both reverting and compensatory viral mutations

artículo científico publicado en 2011

Properties of a herpes simplex virus multiple immediate-early gene-deleted recombinant as a vaccine vector

artículo científico publicado en 2006

Prospective monitoring reveals dynamic levels of T cell immunity to Mycobacterium tuberculosis in HIV infected individuals

artículo científico publicado en 2012

Rare HLA drive additional HIV evolution compared to more frequent alleles

artículo científico publicado en 2009

Reduced Expression of Siglec-7, NKG2A and CD57 on Terminally Differentiated CD56-CD16+ NK Cell Subset is associated with NK Cell Dysfunction in Chronic HIV-1 clade C Infection

artículo científico publicado en 2017

Regulatory T cells expanded from HIV-1-infected individuals maintain phenotype, TCR repertoire and suppressive capacity.

scientific article published on 03 February 2014

Relationship of Human Immunodeficiency Virus Viral Load in Cerebrospinal Fluid and Plasma in Patients Co-infected With Cryptococcal Meningitis

artículo científico publicado en 2017

Replicative capacity of human immunodeficiency virus type 1 transmitted from mother to child is associated with pediatric disease progression rate

artículo científico publicado en 2010

Resistance fighter. Interview by Brendan Borrell

artículo científico publicado en 2012

Resistance of Major Histocompatibility Complex Class B (MHC-B) to Nef-Mediated Downregulation Relative to that of MHC-A Is Conserved among Primate Lentiviruses and Influences Antiviral T Cell Responses in HIV-1-Infected Individuals

artículo científico publicado en 2017

Role of HIV-specific CD8(+) T cells in pediatric HIV cure strategies after widespread early viral escape.

artículo científico publicado en 2017

S04-06 OA. Polyvalent Gag-specific CD8 T-cells with enhanced functional properties are enriched in HIV-1 clade C infected individuals with lower viral loads

artículo científico publicado en 2009

Selection of an HLA-C*03:04-Restricted HIV-1 p24 Gag Sequence Variant Is Associated with Viral Escape from KIR2DL3+ Natural Killer Cells: Data from an Observational Cohort in South Africa

artículo científico publicado en 2015

Sex Differences in Antiretroviral Therapy Initiation in Pediatric HIV Infection

artículo científico publicado en 2015

Short communication: CD8(+) T cell polyfunctionality profiles in progressive and nonprogressive pediatric HIV type 1 infection

artículo científico publicado en 2011

Soluble CD14 as a Diagnostic Biomarker for Smear-Negative HIV-Associated Tuberculosis.

artículo científico publicado en 2018

Subtype-Specific Differences in Gag-Protease-Driven Replication Capacity Are Consistent with Intersubtype Differences in HIV-1 Disease Progression

artículo científico publicado en 2017

Subtype-specific differences in Gag-protease replication capacity of HIV-1 isolates from East and West Africa

artículo científico publicado en 2021

TRIM E3 ligases in HIV infection: can these intrinsic immunity factors be harnessed for novel vaccines or therapies?

scientific article published on July 2011

TRIM5α and TRIM22 are differentially regulated according to HIV-1 infection phase and compartment

artículo científico publicado en 2014

Temporal reduction of HIV type 1 viral load in breast milk by single-dose nevirapine during prevention of MTCT

artículo científico publicado en 2009

The fitness landscape of HIV-1 gag: advanced modeling approaches and validation of model predictions by in vitro testing

artículo científico publicado en 2014

The hypervariable HIV-1 capsid protein residues comprise HLA-driven CD8+ T-cell escape mutations and covarying HLA-independent polymorphisms

artículo científico publicado en 2010

The role of mucosal-associated invariant T cells in infectious diseases

artículo científico publicado en 2016

Translating HIV sequences into quantitative fitness landscapes predicts viral vulnerabilities for rational immunogen design

artículo científico publicado en 2013

Tuberculosis distorts the inhibitory impact of interleukin-10 in HIV infection

artículo científico publicado en 2014

Tuberculous meningitis is associated with higher cerebrospinal HIV-1 viral loads compared to other HIV-1-associated meningitides

artículo científico publicado en 2018

Unmet needs of high-risk mothers reduce success of antiretroviral treatment in HIV-infected infants

Use of dried blood spots for the determination of genetic variation of interleukin-10, killer immunoglobulin-like receptor and HLA class I genes

artículo científico publicado en 2011

Utility of a novel lipoarabinomannan assay for the diagnosis of tuberculous meningitis in a resource-poor high-HIV prevalence setting

artículo científico publicado en 2009

Viral control in chronic HIV-1 subtype C infection is associated with enrichment of p24 IgG1 with Fc effector activity.

artículo científico publicado en 2018

Viral immunology. Comprehensive serological profiling of human populations using a synthetic human virome

artículo científico publicado en 2015

Vulnerable targets in HIV-1 Pol for attenuation-based vaccine design

artículo científico publicado en 2020

Widespread impact of HLA restriction on immune control and escape pathways of HIV-1

artículo científico publicado en 2012

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