Lista de obras - Jeremy K. Nicholson - Dominio Público Uruguay

-Omics dreams of personalized healthcare

scientific article published on 01 September 2006

19F NMR spectroscopic investigation into the absorption and metabolism of 3-trifluoromethylaniline in Eisenia veneta

artículo científico publicado en 2003

19F and 1H magnetic resonance strategies for metabolic studies on fluorinated xenobiotics: Application to flurbiprofen [2-(2-fluoro-4-biphenylyl)propionic acid]

artículo científico publicado en 1990

19F-NMR and directly coupled 19F/1H-HPLC-NMR spectroscopic investigations of the metabolism of the model ecotoxin 3-trifluoromethylaniline in the earthworm species Eisenia veneta

artículo científico publicado en 2002

1H HR-MAS NMR spectroscopy of tumor-induced local metabolic "field-effects" enables colorectal cancer staging and prognostication

article

1H NMR Global Metabolic Phenotyping of Acute Pancreatitis in the Emergency Unit

artículo científico publicado en 2014

1H NMR and UPLC-MS(E) statistical heterospectroscopy: characterization of drug metabolites (xenometabolome) in epidemiological studies

artículo científico publicado en 2008

1H NMR and UPLC-MSEStatistical Heterospectroscopy: Characterization of Drug Metabolites (Xenometabolome) in Epidemiological Studies

artículo científico publicado en 2008

1H NMR spectroscopic and histopathological studies on propyleneimine-induced renal papillary necrosis in the rat and the multimammate desert mouse (Mastomys natalensis).

artículo científico publicado en 1997

1H NMR spectroscopy-based interventional metabolic phenotyping: a cohort study of rheumatoid arthritis patients.

artículo científico publicado en 2010

1H and 2H NMR spectroscopic studies on the metabolism and biochemical effects of 2-bromoethanamine in the rat

article

1H-NMR spectroscopy of biofluids and the investigation of xenobiotic-induced changes in liver biochemistry

artículo científico publicado en 1990

2-Furoylglycine as a Candidate Biomarker of Coffee Consumption

artículo científico publicado en 2015

2.7.5. HPLC/NMR and related hyphenated NMR methods

600 MHz 1H-NMR spectroscopy of human cerebrospinal fluid: effects of sample manipulation and assignment of resonances

artículo científico publicado en 1993

750 MHz 1H NMR spectroscopy characterisation of the complex metabolic pattern of urine from patients with inborn errors of metabolism: 2-hydroxyglutaric aciduria and maple syrup urine disease

artículo científico publicado en 1997

750 MHz 1H-NMR spectroscopy of human blood plasma

scientific article published on 01 April 1993

750 MHz HPLC-NMR spectroscopic identification of rat microsomal metabolites of phenoxypyridines

artículo científico publicado en 1997

750 MHz HPLC−NMR Spectroscopic Studies on the Separation and Characterization of the Positional Isomers of the Glucuronides of 6,11-Dihydro-11- oxodibenz[b,e]oxepin-2-acetic Acid

artículo científico publicado en 1996

750-MHz directly coupled HPLC-NMR: Application for the sequential characterization of the positional isomers and anomers of 2-, 3-, and 4-fluorobenzoic acid glucuronides in equilibrium mixtures

article published in 1995

A Metabolic Entropy Approach for Measurements of Systemic Metabolic Disruptions in Patho-Physiological States

artículo científico publicado en 2010

A Metabolite Array Technology for Precision Medicine

artículo científico publicado en 2021

A QSAR investigation of dermal and respiratory chemical sensitizers based on computational chemistry properties

artículo científico publicado en 2009

A Unified Conceptual Framework for Metabolic Phenotyping in Diagnosis and Prognosis

artículo científico publicado en 2019

A comparison of collision cross section values obtained via travelling wave ion mobility-mass spectrometry and ultra high performance liquid chromatography-ion mobility-mass spectrometry: Application to the characterisation of metabolites in rat uri

artículo científico publicado en 2019

A comparison of quantitative NMR and radiolabelling studies of the metabolism and excretion of Statil (3-(4-bromo-2-fluorobenzyl)-4-oxo-3H-phthalazin-1-ylacetic acid) in the rat.

artículo científico publicado en 2002

A comparison of self-reported analgesic use and detection of urinary ibuprofen and acetaminophen metabolites by means of metabonomics: the INTERMAP Study

artículo científico publicado en 2012

A genome-wide metabolic QTL analysis in Europeans implicates two loci shaped by recent positive selection

artículo científico publicado en 2011

A metabolic phenotyping approach to understanding relationships between metabolic syndrome and breast tumour responses to chemotherapy

artículo científico publicado en 2011

A metabolic system-wide characterisation of the pig: a model for human physiology

article

A metabonomic investigation of hepatotoxicity using diffusion-edited 1H NMR spectroscopy of blood serum

artículo científico publicado en 2003

A metabonomic strategy for the detection of the metabolic effects of chamomile (Matricaria recutita L.) ingestion

artículo científico publicado en 2005

A multiplexed targeted assay for high-throughput quantitative analysis of serum methylamines by ultra performance liquid chromatography coupled to high resolution mass spectrometry

artículo científico publicado en 2016

A novel LC-MS approach for the detection of metabolites in DMPK studies.

artículo científico publicado en 2010

A novel methodology for in vivo endoscopic phenotyping of colorectal cancer based on real-time analysis of the mucosal lipidome: a prospective observational study of the iKnife

artículo científico publicado en 2016

A pattern recognition approach to the comparison of PMR and clinical chemical data for classification of nephrotoxicity.

artículo científico publicado en 1990

A prospective analysis of mucosal microbiome-metabonome interactions in colorectal cancer using a combined MAS 1HNMR and metataxonomic strategy

artículo científico publicado en 2017

A prospective cohort analysis of gut microbial co-metabolism in Alaska Native and rural African people at high and low risk of colorectal cancer

scientific article published on 01 February 2020

A rapid simple approach to screening pharmaceutical products using ultra-performance LC coupled to time-of-flight mass spectrometry and pattern recognition

artículo científico publicado en 2008

A simultaneous exploratory and quantitative amino acid and biogenic amine metabolic profiling platform for rapid disease phenotyping via UPLC-QToF-MS

scientific article published on 07 November 2020

A study of metabolic compartmentation in the rat heart and cardiac mitochondria using high-resolution magic angle spinning 1H NMR spectroscopy.

artículo científico publicado en 2003

A study of the metabolism of dimethylformamide in the rat by high resolution proton NMR spectroscopy

artículo científico publicado en 1989

A top-down systems biology view of microbiome-mammalian metabolic interactions in a mouse model

artículo científico publicado en 2007

A two-way interaction between methotrexate and the gut microbiota of male Sprague Dawley rats

artículo científico publicado en 2020

A validated UPLC-MS/MS assay for the quantification of amino acids and biogenic amines in rat urine

scientific article published on 29 December 2018

APPLICATION OF HIGH RESOLUTION H-NMR SPECTROSCOPY TO THE DETECTION OF PENICILLAMINE AND ITS METABOLITES IN HUMAN URINE

scientific article published on 01 January 1988

Abnormal lipid profile of dystrophic cardiac tissue as demonstrated by one- and two-dimensional magic-angle spinning (1)H NMR spectroscopy

artículo científico publicado en 2001

Acute renal failure following accidental cutaneous absorption of phenol: application of NMR urinalysis to monitor the disease process.

artículo científico publicado en 1989

Addressing the challenge of limited sample volumes inin vitrostudies with capillary-scale microfluidic LC–MS/MS

article

Age and microenvironment outweigh genetic influence on the Zucker rat microbiome

artículo científico publicado en 2014

An Analytical Pipeline for Quantitative Characterization of Dietary Intake: Application To Assess Grape Intake

article

An NMR study of the metabolic fate of 2-, 3- and 4-fluorobenzyl alcohols in the rat: detection of N-acetylcysteinyl conjugates as minor metabolites in urine

artículo científico publicado en 2003

An NMR-based metabonomic approach to investigate the biochemical consequences of genetic strain differences: application to the C57BL10J and Alpk:ApfCD mouse

artículo científico publicado en 2000

An NMR-based metabonomic approach to the investigation of coelomic fluid biochemistry in earthworms under toxic stress.

artículo científico publicado en 2001

An hypothesis for a mechanism underlying hepatotoxin-induced hypercreatinuria

artículo científico publicado en 2003

An integrated ceramic, micro-fluidic device for the LC/MS/MS analysis of pharmaceuticals in plasma

artículo científico publicado en 2015

An integrated metabonomic approach to describe temporal metabolic disregulation induced in the rat by the model hepatotoxin allyl formate.

artículo científico publicado en 2006

An integrated metabonomic investigation of acetaminophen toxicity in the mouse using NMR spectroscopy

artículo científico publicado en 2003

An integrated reverse functional genomic and metabolic approach to understanding orotic acid-induced fatty liver

artículo científico publicado en 2004

Analysis of biological fluids using 600 MHz proton NMR spectroscopy: Application of homonuclear two-dimensional J-resolved spectroscopy to urine and blood plasma for spectral simplification and assignment

article

Analysis of polar urinary metabolites for metabolic phenotyping using supercritical fluid chromatography and mass spectrometry

artículo científico publicado en 2016

Analysis of time-related metabolic fluctuations induced by ethionine in the rat.

artículo científico publicado en 2007

Analytic properties of statistical total correlation spectroscopy based information recovery in 1H NMR metabolic data sets

artículo científico publicado en 2009

Analytical reproducibility in (1)H NMR-based metabonomic urinalysis

artículo científico publicado en 2002

Analytical technologies for metabonomics and metabolomics, and multi-omic information recovery

article

Application of (1)H- and (19)F-NMR spectroscopy in the investigation of the urinary and biliary excretion of 3,5-, 2,4-ditrifluoromethylbenzoic and pentafluorobenzoic acids in rat.

artículo científico publicado en 2002

Application of Directly Coupled HPLC NMR to Separation and Characterization of Lipoproteins from Human Serum

scientific article published on 01 March 2001

Application of Directly Coupled HPLC-NMR-MS/MS to the Identification of Metabolites of 5-Trifluoromethylpyridone (2-Hydroxy-5-trifluoromethylpyridine) in Hydroponically Grown Plants

article

Application of NMR-based metabolomics to the investigation of salt stress in maize (Zea mays).

artículo científico publicado en 2010

Application of biofluid 1 H nuclear magnetic resonance-based metabonomic techniques for the analysis of the biochemical effects of dietary isoflavones on human plasma profile

article

Application of chemometrics to 1H NMR spectroscopic data to investigate a relationship between human serum metabolic profiles and hypertension

artículo científico publicado en 2003

Application of chemometrics to the 1H NMR spectra of apple juices: discrimination between apple varieties

article

Application of directly coupled LC–NMR–MS to the structural elucidation of metabolites of the HIV-1 reverse-transcriptase inhibitor BW935U83

article

Application of directly coupled high performance liquid chromatography-NMR-mass spectometry and 1H NMR spectroscopic studies to the investigation of 2,3-benzofuran metabolism in Sprague-Dawley rats

artículo científico publicado en 2002

Application of inductively coupled plasma mass spectrometry and high-performance liquid chromatography—with parallel electrospray mass spectrometry to the investigation of the disposition and metabolic fate of 2-, 3- and 4-iodobenzoic acids in the

artículo científico publicado en 2004

Application of novel solid phase extraction-NMR protocols for metabolic profiling of human urine

artículo científico publicado en 2019

Application of orthogonal signal correction to minimise the effects of physical and biological variation in high resolution 1H NMR spectra of biofluids

artículo científico publicado en 2002

Application of the FLIPSY pulse sequence for increased sensitivity in 1H NMR-based metabolic profiling studies

artículo científico publicado en 2008

Application of the one-dimensional TOCSY pulse sequence in 750 MHz 1H-NMR spectroscopy for assignment of endogenous metabolite resonances in biofluids

scientific article published on 01 May 1994

Assessment of Analytical Reproducibility of1H NMR Spectroscopy Based Metabonomics for Large-Scale Epidemiological Research: the INTERMAP Study

artículo científico publicado en 2006

Assignment of 1H nuclear magnetic resonance visible polyunsaturated fatty acids in BT4C gliomas undergoing ganciclovir-thymidine kinase gene therapy-induced programmed cell death

artículo científico publicado en 2003

Assignment of the 750 MHz 1H NMR resonances from a mixture of transacylated ester glucuronic acid conjugates with the aid of oversampling and digital filtering during acquisition

artículo científico publicado en 1995

Association of Untargeted Urinary Metabolomics and Lung Cancer Risk Among Never-Smoking Women in China

scientific article published on 04 September 2019

Automatic Spectroscopic Data Categorization by Clustering Analysis (ASCLAN): A Data-Driven Approach for Distinguishing Discriminatory Metabolites for Phenotypic Subclasses

artículo científico publicado en 2016

Automatic alignment of individual peaks in large high-resolution spectral data sets

artículo científico publicado en 2004

Automatic data reduction and pattern recognition methods for analysis of 1H nuclear magnetic resonance spectra of human urine from normal and pathological states.

artículo científico publicado en 1994

BASIS: High-performance bioinformatics platform for processing of large-scale mass spectrometry imaging data in chemically augmented histology

artículo científico publicado en 2018

Bacterial adaptation to the gut environment favors successful colonization: microbial and metabonomic characterization of a simplified microbiota mouse model

artículo científico publicado en 2011

Bariatric surgery modulates circulating and cardiac metabolites

artículo científico publicado en 2013

Bidirectional communication between the Aryl hydrocarbon Receptor (AhR) and the microbiome tunes host metabolism

artículo científico publicado en 2016

Bidirectional correlation of NMR and capillary electrophoresis fingerprints: a new approach to investigating Schistosoma mansoni infection in a mouse model

artículo científico publicado en 2010

Bile UPLC-MS fingerprinting and bile acid fluxes during human liver transplantation

article

Bile acid profiling and quantification in biofluids using ultra-performance liquid chromatography tandem mass spectrometry

artículo científico publicado en 2015

Biochemical characterisation of para-aminophenol-induced nephrotoxic lesions in the F344 rat

article

Biochemical characterization of rat intestine development using high-resolution magic-angle-spinning 1H NMR spectroscopy and multivariate data analysis

artículo científico publicado en 2005

Biochemical classification of kidney carcinoma biopsy samples using magic-angle-spinning 1H nuclear magnetic resonance spectroscopy

article published in 1998

Biofluid 1H NMR-based metabonomic techniques in nutrition research - metabolic effects of dietary isoflavones in humans

artículo científico publicado en 2005

Broad-Ranging Natural Metabotype Variation Drives Physiological Plasticity in Healthy Control Inbred Rat Strains

artículo científico publicado en 2011

COMET and the Challenge of Drug Safety Screening

COMET and the challenge of drug safety screening

scientific article published on 25 September 2007

Cadmium and mercury nephrotoxicity

artículo científico publicado en 1983

Cellular acidosis in rodents exposed to cadmium is caused by adaptation of the tissue rather than an early effect of toxicity

artículo científico publicado en 2007

Cellular environment of metabolites and a metabonomic study of tamoxifen in endometrial cells using gradient high resolution magic angle spinning 1H NMR spectroscopy

artículo científico publicado en 2003

Cephaloridine-induced nephrotoxicity in the Fischer 344 rat: proton NMR spectroscopic studies of urine and plasma in relation to conventional clinical chemical and histopathological assessments of nephronal damage

artículo científico publicado en 1992

Cervical intraepithelial neoplasia disease progression is associated with increased vaginal microbiome diversity

artículo científico publicado en 2015

Characterisation of impurities in bulk drug batches of fluticasone propionate using directly coupled HPLC–NMR spectroscopy and HPLC–MS

scientific article published on 01 December 1997

Characterisation of putative pentose-containing conjugates as minor metabolites of 4-bromoaniline present in the urine of rats following intraperitoneal administration

artículo científico publicado en 2003

Characterization and quantification of metabolites of racemic ketoprofen excreted in urine following oral administration to man by 1H-NMR spectroscopy, directly coupled HPLC-MS and HPLC-NMR, and circular dichroism

artículo científico publicado en 2004

Characterization of Metabolites in IntactStreptomyces citricolorCulture Supernatants Using High-Resolution Nuclear Magnetic Resonance and Directly Coupled High-Pressure Liquid Chromatography–Nuclear Magnetic Resonance Spectroscopy

article

Characterization of metabolic responses to healthy diets and association with blood pressure: application to the Optimal Macronutrient Intake Trial for Heart Health (OmniHeart), a randomized controlled study

artículo científico publicado en 2018

Characterization of the biochemical effects of 1-nitronaphthalene in rats using global metabolic profiling by NMR spectroscopy and pattern recognition.

artículo científico publicado en 2005

Chemical mapping of the colorectal cancer microenvironment via MALDI imaging mass spectrometry (MALDI-MSI) reveals novel cancer-associated field effects

artículo científico publicado en 2013

Chemical shift calibration of 1H MAS NMR liver tissue spectra exemplified using a study of glycine protection of galactosamine toxicity

artículo científico publicado en 2009

Chemo-informatic strategy for imaging mass spectrometry-based hyperspectral profiling of lipid signatures in colorectal cancer

scientific article published on 07 January 2014

Chemometric Models for Toxicity Classification Based on NMR Spectra of Biofluids

article

Chemometric analysis of biofluids following toxicant induced hepatotoxicity: a metabonomic approach to distinguish the effects of 1-naphthylisothiocyanate from its products

artículo científico publicado en 2005

Chiral Metabonomics: 1H NMR-Based Enantiospecific Differentiation of Metabolites in Human Urine via Direct Cosolvation with β-Cyclodextrin

article

Chirality

article

Choline containing metabolites during cell transfection: an insight into magnetic resonance spectroscopy detectable changes

artículo científico publicado en 2001

Classification of toxin-induced changes in 1H NMR spectra of urine using an artificial neural network.

artículo científico publicado en 1995

Cluster analysis statistical spectroscopy using nuclear magnetic resonance generated metabolic data sets from perturbed biological systems

artículo científico publicado en 2009

Colonization-induced host-gut microbial metabolic interaction

artículo científico publicado en 2011

Combined HPLC, NMR Spectroscopy, and Ion-Trap Mass Spectrometry with Application to the Detection and Characterization of Xenobiotic and Endogenous Metabolites in Human Urine

article

Combined proteomic and metabonomic studies in three genetic forms of the renal Fanconi syndrome

artículo científico publicado en 2007

Comparative biochemical effects of low doses of mercury II chloride in the F344 rat and the multimammate mouse (Mastomys natalensis)

scientific article published on 01 May 1996

Comparative distributions of zinc, cadmium and mercury in the tissues of experimental mice

scientific article published on 01 January 1984

Comparative metabonomics of differential hydrazine toxicity in the rat and mouse

artículo científico publicado en 2005

Comparative studies on the nephrotoxicity of 2-bromoethanamine hydrobromide in the Fischer 344 rat and the multimammate desert mouse (Mastomys natalensis).

artículo científico publicado en 1995

Comparison of Maximum Quantum Filtered NMR Spectroscopy (MAXY NMR) and Other Two-Dimensional NMR Approaches for Resonance Assignment of Peptides

Comparison of in vivo 1H MRS of human brain tumours with 1H HR-MAS spectroscopy of intact biopsy samples in vitro

artículo científico publicado en 1999

Compartmentation of metabolism probed by [2-13C]alanine: improved 13C NMR sensitivity using a CryoProbe detects evidence of a glial metabolon

artículo científico publicado en 2003

Conception, Implementation and Operation of Large-Scale Metabolic Phenotyping Centres: Phenome Centres

Contemporary issues in toxicology the role of metabonomics in toxicology and its evaluation by the COMET project

artículo científico publicado en 2003

Contributors

Coordinated multitissue transcriptional and plasma metabonomic profiles following acute caloric restriction in mice.

artículo científico publicado en 2006

Correction to 2-Furoylglycine as a Candidate Biomarker of Coffee Consumption

artículo científico publicado en 2016

Coupling of HPLC with 19F- and 1H-NMR spectroscopy to investigate the human urinary excretion of flurbiprofen metabolites

artículo científico publicado en 1993

Cryogenic Probe13C NMR Spectroscopy of Urine for Metabonomic Studies

article

Curve-fitting method for direct quantitation of compounds in complex biological mixtures using 1H NMR: application in metabonomic toxicology studies

artículo científico publicado en 2005

Data-Driven Approach for Metabolite Relationship Recovery in Biological 1H NMR Data Sets Using Iterative Statistical Total Correlation Spectroscopy ⬇️

artículo científico publicado el 16 de febrero de 2011

Deep learning and 3D-DESI imaging reveal the hidden metabolic heterogeneity of cancer

artículo científico publicado en 2017

Degradation of 4-fluorobiphenyl in soil investigated by 19F NMR spectroscopy and 10C radiolabelling analysis

artículo científico publicado en 1999

Detection of Urinary Drug Metabolite (Xenometabolome) Signatures in Molecular Epidemiology Studies via Statistical Total Correlation (NMR) Spectroscopy

article published in 2008

Detection of mono- and di-hexoses as metabolites of 4-bromoaniline using HPLC-TOF-MS/MS.

artículo científico publicado en 2003

Detection of urinary drug metabolite (xenometabolome) signatures in molecular epidemiology studies via statistical total correlation (NMR) spectroscopy.

artículo científico publicado en 2007

Detection ofin vivo biomarkers of phospholipidosis using NMR-based metabonomic approaches

article

Determination of the relative NH proton lifetimes of the peptide analogue viomycin in aqueous solution by NMR-based diffusion measurement

artículo científico publicado el 1 de enero de 1999

Deuterium NMR spectroscopy of biofluids for the identification of drug metabolites: Application to N,N-dimethylformamide

artículo científico publicado en 1993

Development and Application of Ultra-Performance Liquid Chromatography-TOF MS for Precision Large Scale Urinary Metabolic Phenotyping.

artículo científico publicado en 2016

Development and Validation of a High-Throughput Ultrahigh-Performance Liquid Chromatography-Mass Spectrometry Approach for Screening of Oxylipins and Their Precursors

artículo científico publicado en 2015

Development and validation of a high performance liquid chromatography-tandem mass spectrometry method for the absolute analysis of 17 α D-amino acids in cooked meals

scientific article published on 04 October 2019

Development of a Pipeline for Exploratory Metabolic Profiling of Infant Urine

artículo científico publicado en 2016

Development of a Rapid Microbore Metabolic Profiling Ultraperformance Liquid Chromatography-Mass Spectrometry Approach for High-Throughput Phenotyping Studies.

artículo científico publicado en 2016

Development of a model for classification of toxin-induced lesions using1H NMR spectroscopy of urine combined with pattern recognition

article

Development of a simple liquid chromatographic method for the separation of mixtures of positional isomers and anomers of synthetic 2-, 3- and 4-fluorobenzoic acid glucuronides formed via acyl migration reactions

article

Development of nanoelectrospray high resolution isotope dilution mass spectrometry for targeted quantitative analysis of urinary metabolites: application to population profiling and clinical studies

article

Dietary Modulation of Gut Microbiota Contributes to Alleviation of Both Genetic and Simple Obesity in Children

artículo científico publicado en 2015

Dietary and social modulation of gut microbiota in the elderly

artículo científico publicado en 2012

Dietary and urinary metabonomic factors possibly accounting for higher blood pressure of black compared with white Americans: results of International Collaborative Study on macro-/micronutrients and blood pressure

artículo científico publicado en 2013

Dietary fibre to reduce colon cancer risk in Alaska Native people: the Alaska FIRST randomised clinical trial protocol

artículo científico publicado en 2021

Dietary minerals in the gastrointestinal tract: hydroxypolymerisation of aluminium is regulated by luminal mucins

artículo científico publicado en 1999

Dietary modulation of gut functional ecology studied by fecal metabonomics

artículo científico publicado en 2010

Differences in Fecal Gut Microbiota, Short-Chain Fatty Acids and Bile Acids Link Colorectal Cancer Risk to Dietary Changes Associated with Urbanization Among Zimbabweans

artículo científico publicado en 2019

Different levels of polybrominated diphenyl ethers (PBDEs) and chlorinated compounds in breast milk from two U.K. Regions

artículo científico publicado en 2004

Diffusion and Relaxation Edited Proton NMR Spectroscopy of Plasma Reveals a High-Fidelity Supramolecular Biomarker Signature of SARS-CoV-2 Infection

scientific article published in 2021

Direct coupling of chromatographic separations to NMR spectroscopy

article

Direct observation of resolved intracellular and extracellular water signals in intact human red blood cells using 1H MAS NMR spectroscopy.

artículo científico publicado en 1997

Direct quantitative trait locus mapping of mammalian metabolic phenotypes in diabetic and normoglycemic rat models

artículo científico publicado en 2007

Directly Coupled 800 MHz HPLC−NMR Spectroscopy of Urine and Its Application to the Identification of the Major Phase II Metabolites of Tolfenamic Acid

artículo científico publicado en 1997

Directly Coupled Chiral HPLC−NMR and HPLC−CD Spectroscopy as Complementary Methods for Structural and Enantiomeric Isomer Identification: Application to Atracurium Besylate

scientific article published in 1999

Directly coupled CZE-NMR and CEC-NMR spectroscopy for metabolite analysis: paracetamol metabolites in human urine

article

Directly coupled HPLC-NMR and HPLC-MS approaches for the rapid characterisation of drug metabolites in urine: application to the human metabolism of naproxen

artículo científico publicado en 2001

Directly coupled HPLC-NMR and HPLC-NMR-MS in pharmaceutical research and development

artículo científico publicado en 2000

Directly coupled high-performance liquid chromatography and nuclear magnetic resonance spectroscopic with chemometric studies on metabolic variation in Sprague--Dawley rats

artículo científico publicado en 2001

Directly-coupled HPLC-NMR spectroscopic studies of metabolism and futile deacetylation of phenacetin in the rat

article

Discovery and validation of urinary metabotypes for the diagnosis of hepatocellular carcinoma in West Africans.

artículo científico publicado en 2014

Distinction between normal and renal cell carcinoma kidney cortical biopsy samples using pattern recognition of (1)H magic angle spinning (MAS) NMR spectra

scholarly article by A. Rosemary Tate et al published April 2000 in NMR in Biomedicine

Dynamic biochemical information recovery in spontaneous human seminal fluid reactions via 1H NMR kinetic statistical total correlation spectroscopy

artículo científico publicado en 2009

Early intervention with Bifidobacterium lactis NCC2818 modulates the host-microbe interface independent of the sustained changes induced by the neonatal environment.

artículo científico publicado en 2017

Early metabolic adaptation in C57BL/6 mice resistant to high fat diet induced weight gain involves an activation of mitochondrial oxidative pathways

artículo científico publicado en 2013

Earthworm species of the genus Eisenia can be phenotypically differentiated by metabolic profiling

article

Effect of the histone deacetylase inhibitor trichostatin a on the metabolome of cultured primary hepatocytes

artículo científico publicado en 2010

Effects of biliary cannulation and buthionine sulphoximine pretreatment on the nephrotoxicity of para-aminophenol in the Fischer 344 rat.

artículo científico publicado en 1990

Effects of probiotic Lactobacillus paracasei treatment on the host gut tissue metabolic profiles probed via magic-angle-spinning NMR spectroscopy

artículo científico publicado en 2007

Environmental metabonomics: applying combination biomarker analysis in earthworms at a metal contaminated site.

artículo científico publicado en 2004

Ethyl glucoside in human urine following dietary exposure: detection by 1H NMR spectroscopy as a result of metabonomic screening of humans

artículo científico publicado en 2004

Evaluation of full-resolution J-resolved 1H NMR projections of biofluids for metabonomics information retrieval and biomarker identification

artículo científico publicado en 2010

Evaluation of high resolution magic-angle coil spinning NMR spectroscopy for metabolic profiling of nanoliter tissue biopsies

article

Evaluation of metabolic variation in normal rat strains from a statistical analysis of 1H NMR spectra of urine

article

Evaluation of the orthogonal projection on latent structure model limitations caused by chemical shift variability and improved visualization of biomarker changes in 1H NMR spectroscopic metabonomic studies.

artículo científico publicado en 2005

Experimental and analytical variation in human urine in 1H NMR spectroscopy-based metabolic phenotyping studies

artículo científico publicado en 2007

Experimental bariatric surgery in rats generates a cytotoxic chemical environment in the gut contents.

artículo científico

Experimental metabonomic model of dietary variation and stress interactions

artículo científico publicado en 2006

Exploration of the direct metabolic effects of mercury II chloride on the kidney of Sprague-Dawley rats using high-resolution magic angle spinning 1H NMR spectroscopy of intact tissue and pattern recognition

artículo científico publicado en 2005

Extraction, interpretation and validation of information for comparing samples in metabolic LC/MS data sets

artículo científico publicado en 2005

Fat, fibre and cancer risk in African Americans and rural Africans

artículo científico publicado en 2015

First example of hepatocyte transplantation to alleviate ornithine transcarbamylase deficiency, monitored by NMR-based metabonomics

artículo científico publicado en 2009

Future Visions for Clinical Metabolic Phenotyping

Gastro-intestinal availability of aluminium from tea

artículo científico publicado en 1993

Generation of Ultrahigh Peak Capacity LC Separations via Elevated Temperatures and High Linear Mobile-Phase Velocities

article

Genetic algorithms for simultaneous variable and sample selection in metabonomics

artículo científico publicado en 2008

Genetic determinants of metabolism in health and disease: from biochemical genetics to genome-wide associations.

artículo científico publicado en 2012

Geometric trajectory analysis of metabolic responses to toxicity can define treatment specific profiles

artículo científico publicado en 2004

Global Systems Biology Through Integration of “Omics” Results

Global metabolic phenotyping in an experimental laparotomy model of surgical trauma

article

Global metabolic profiling of animal and human tissues via UPLC-MS.

artículo científico publicado en 2012

Global metabolic profiling procedures for urine using UPLC–MS

article

Global metabolic responses of NMRI mice to an experimental Plasmodium berghei infection

artículo científico publicado en 2008

Global metabolic responses of mice to Trypanosoma brucei brucei infection

artículo científico publicado en 2008

Global systems biology and personalized healthcare solutions

scientific article published on 01 April 2006

Global systems biology, personalized medicine and molecular epidemiology

artículo científico publicado en 2006

Global urinary metabolic profiling procedures using gas chromatography–mass spectrometry

Gut Microbiota Modulate the Metabolism of Brown Adipose Tissue in Mice

artículo científico publicado en 2011

Gut microbiome interactions with drug metabolism, efficacy, and toxicity

artículo científico publicado en 2016

Gut microbiome modulates the toxicity of hydrazine: a metabonomic study

article

Gut microbiome-host interactions in health and disease ⬇️

artículo científico publicado el 4 de marzo de 2011

Gut microbiomes of Malawian twin pairs discordant for kwashiorkor

artículo científico publicado en 2013

Gut microbiota composition and activity in relation to host metabolic phenotype and disease risk

artículo científico publicado en 2012

Gut microbiota modulation of chemotherapy efficacy and toxicity.

artículo científico publicado en 2017

Gut microbiota: a potential new territory for drug targeting

artículo científico publicado en 2008

Gut microorganisms, mammalian metabolism and personalized health care

artículo científico publicado en 2005

HILIC-UPLC-MS for Exploratory Urinary Metabolic Profiling in Toxicological Studies

article

HPLC/1H NMR spectroscopic studies of the reactive alpha-1-O-acyl isomer formed during acyl migration of S-naproxen beta-1-O-acyl glucuronide

artículo científico publicado en 2001

Hepatotoxin-induced hypercreatinaemia and hypercreatinuria: their relationship to one another, to liver damage and to weakened nutritional status

artículo científico publicado en 2003

Hepatotoxin-induced hypertaurinuria: a proton NMR study

article

Hepatotoxin-induced hypertyrosinemia and its toxicological significance

Heteronuclear 19F-1H statistical total correlation spectroscopy as a tool in drug metabolism: study of flucloxacillin biotransformation

artículo científico publicado en 2008

Heteronuclear 1H-31P statistical total correlation NMR spectroscopy of intact liver for metabolic biomarker assignment: application to galactosamine-induced hepatotoxicity

artículo científico publicado en 2007

High resolution "ultra performance" liquid chromatography coupled to oa-TOF mass spectrometry as a tool for differential metabolic pathway profiling in functional genomic studies.

artículo científico publicado en 2005

High resolution 1H NMR spectroscopic studies on dynamic biochemical processes in incubated human seminal fluid samples

article

High resolution NMR spectroscopic studies on the metabolism and futile deacetylation of 4-hydroxyacetanilide (paracetamol) in the rat

article

High resolution proton magnetic resonance spectroscopy of biological fluids

High resolution proton magnetic resonance spectroscopy of cyst fluids from patients with polycystic kidney disease

artículo científico publicado en 1992

High-Field Deuterium Nuclear Magnetic Resonance Spectroscopic Monitoring of the Pharmacokinetics of Selectively Deuterated Benzoic Acid in Man

artículo científico publicado en 1994

High-Speed Quantitative UPLC-MS Analysis of Multiple Amines in Human Plasma and Serum via Precolumn Derivatization with 6-Aminoquinolyl-N-hydroxysuccinimidyl Carbamate: Application to Acetaminophen-Induced Liver Failure.

artículo científico publicado en 2017

High-Throughput Microbore UPLC–MS Metabolic Phenotyping of Urine for Large-Scale Epidemiology Studies

article

High-performance liquid chromatography and inductively coupled plasma mass spectrometry (HPLC-ICP-MS) for the analysis of xenobiotic metabolites in rat urine: application to the metabolites of 4-bromoaniline

artículo científico publicado en 2000

High-performance liquid chromatography linked to inductively coupled plasma mass spectrometry and orthogonal acceleration time-of-flight mass spectrometry for the simultaneous detection and identification of metabolites of 2-bromo-4-trifluoromethyl

artículo científico publicado en 2001

High-performance liquid chromatography/inductively coupled plasma mass spectrometry with iodine-specific detection for profiling the metabolites produced in the earthworm Eisenia veneta by exposure to 2-fluoro-4-iodoaniline

artículo científico publicado en 2003

High-performance liquid chromatography/mass spectrometric and proton nuclear magnetic resonance spectroscopic studies of the transacylation and hydrolysis of the acyl glucuronides of a series of phenylacetic acids in buffer and human plasma

artículo científico publicado en 2010

High-resolution (1)H NMR and magic angle spinning NMR spectroscopic investigation of the biochemical effects of 2-bromoethanamine in intact renal and hepatic tissue

artículo científico publicado en 2001

High-resolution diffusion and relaxation-edited magic angle spinning 1H NMR spectroscopy of intact liver tissue

artículo científico publicado en 2003

High-resolution magic angle spinning (1)H NMR spectroscopy of intact liver and kidney: optimization of sample preparation procedures and biochemical stability of tissue during spectral acquisition

artículo científico publicado en 2000

High-resolution magic angle spinning 1H NMR spectroscopic studies on intact rat renal cortex and medulla

scientific article published on 01 June 1999

High-resolution magic angle spinning NMR spectroscopy: Application to biomedical studies

article

High-resolution magic-angle-spinning 1H NMR spectroscopy reveals different responses in choline-containing metabolites upon gene therapy-induced programmed cell death in rat brain glioma.

artículo científico publicado en 2005

High-resolution magic-angle-spinning NMR spectroscopy for metabolic profiling of intact tissues

artículo científico publicado en 2010

High-throughput 1H NMR-based metabolic analysis of human serum and urine for large-scale epidemiological studies: validation study

artículo científico publicado en 2008

Hippurate: the natural history of a mammalian-microbial cometabolite.

artículo científico publicado en 2013

How has healthcare research performance been assessed?: a systematic review

artículo científico publicado en 2011

Human metabolic phenotype diversity and its association with diet and blood pressure.

artículo científico publicado en 2008

Human metabolic phenotypes link directly to specific dietary preferences in healthy individuals

artículo científico publicado en 2007

Human metabolic profiles are stably controlled by genetic and environmental variation

artículo científico publicado en 2011

Hyperspectral visualization of mass spectrometry imaging data.

artículo científico publicado en 2013

Hyphenated methods

Identification of metabolites in human hepatic bile using 800 MHz 1H NMR spectroscopy, HPLC-NMR/MS and UPLC-MS.

artículo científico publicado en 2008

Identification of novel hydrazine metabolites by 15N-NMR

artículo científico publicado en 1991

Identification of the Positional Isomers of 2-Fluorobenzoic acid 1-O-Acyl Glucuronide by Directly Coupled HPLC-NMR

scientific article published in 1995

Identification of the urinary metabolites of 4-bromoaniline and 4-bromo-[carbonyl-13C]-acetanilide in rat.

artículo científico publicado en 2002

Identifying unknown metabolites using NMR-based metabolic profiling techniques

artículo científico publicado en 2020

Impact of a care coordination and support strategic partnership on clinical outcomes.

artículo científico publicado en 2008

Impact of analytical bias in metabonomic studies of human blood serum and plasma

artículo científico publicado en 2006

Impact of the gut microbiota on inflammation, obesity, and metabolic disease

artículo científico publicado en 2016

Implementation of molecular phenotyping approaches in the personalized surgical patient journey

artículo científico publicado en 2012

Improved Spatial Resolution of Metabolites in Tissue Biopsies Using High-Resolution Magic-Angle-Spinning Slice Localization NMR Spectroscopy

artículo científico publicado en 2020

Improved analysis of multivariate data by variable stability scaling: application to NMR-based metabolic profiling

article

Improvement in the characterization of minor drug metabolites from HPLC-NMR studies through the use of quantified maximum entropy processing of NMR spectra

artículo científico publicado en 1994

Impurity profiling in bulk pharmaceutical batches using 19F NMR spectroscopy and distinction between monomeric and dimeric impurities by NMR-based diffusion measurements

artículo científico publicado en 1999

In Vivo Endoscopic Tissue Identification by Rapid Evaporative Ionization Mass Spectrometry (REIMS)

artículo científico publicado en 2015

In-vitro identification of distinctive metabolic signatures of intact varicose vein tissue via magic angle spinning nuclear magnetic resonance spectroscopy

artículo científico publicado en 2012

Incomplete Systemic Recovery and Metabolic Phenoreversion in Post-Acute-Phase Nonhospitalized COVID-19 Patients: Implications for Assessment of Post-Acute COVID-19 Syndrome

Induction of 5-oxoprolinuria in the rat following chronic feeding with N -acetyl 4-aminophenol (paracetamol)

artículo científico publicado en 1993

Integrated Analytical and Statistical Two-Dimensional Spectroscopy Strategy for Metabolite Identification: Application to Dietary Biomarkers. ⬇️

artículo científico publicado en 2017

Integrated HPLC-MS and (1)H-NMR spectroscopic studies on acyl migration reaction kinetics of model drug ester glucuronides.

artículo científico publicado en 2010

Integrated application of transcriptomics and metabonomics yields new insight into the toxicity due to paracetamol in the mouse

artículo científico publicado en 2004

Integrated cytokine and metabolic analysis of pathological responses to parasite exposure in rodents

artículo científico publicado en 2010

Integrated histopathological and urinary metabonomic investigation of the pathogenesis of microcystin-LR toxicosis

artículo científico publicado en 2012

Integrated metabonomic analysis of bromobenzene-induced hepatotoxicity: novel induction of 5-oxoprolinosis

article

Integrated metabonomic analysis of the multiorgan effects of hydrazine toxicity in the rat.

artículo científico publicado en 2005

Integrated metabonomic-proteomic analysis of an insect-bacterial symbiotic system.

artículo científico publicado en 2010

Integrative Modelling of Quantitative Plasma Lipoprotein, Metabolic and Amino Acid Data Reveals a Multi-organ Pathological Signature of SARS-CoV-2 Infection

artículo científico publicado en 2020

Integrative Top-Down System Metabolic Modeling in Experimental Disease States via Data-Driven Bayesian Methods

Integrative top-down system metabolic modeling in experimental disease states via data-driven Bayesian methods

artículo científico publicado en 2008

Intestinal ischemia/reperfusion injury: defining the role of the gut microbiome

artículo científico publicado en 2009

Intra- and Interlaboratory Reproducibility of Ultra Performance Liquid Chromatography–Time-of-Flight Mass Spectrometry for Urinary Metabolic Profiling

article

Intra- and inter-omic fusion of metabolic profiling data in a systems biology framework

article by Selena E. Richards et al published November 2010 in Chemometrics and Intelligent Laboratory Systems

Intraoperative tissue identification using rapid evaporative ionization mass spectrometry

artículo científico publicado en 2013

Investigation of basic mobile phases with positive ESI LC-MS for metabonomics studies

artículo científico publicado en 2012

Investigation of the feasibility of directly-coupled HPLC-NMR with 2H detection with application to the metabolism of N-dimethylformamide-d7

artículo científico publicado en 1997

Investigation of the metabolic fate of 2-, 3- and 4-bromobenzoic acids in bile-duct-cannulated rats by inductively coupled plasma mass spectrometry and high-performance liquid chromatography/inductively coupled plasma mass spectrometry/electrospray m

artículo científico publicado en 2005

Investigations into biochemical changes due to diurnal variation and estrus cycle in female rats using high-resolution (1)H NMR spectroscopy of urine and pattern recognition

artículo científico publicado en 2001

Ion mobility spectrometry combined with ultra performance liquid chromatography/mass spectrometry for metabolic phenotyping of urine: Effects of column length, gradient duration and ion mobility spectrometry on metabolite detection.

artículo científico publicado en 2017

Iron status influences non-alcoholic fatty liver disease in obesity through the gut microbiome

artículo científico publicado en 2021

Isotopic enrichment enhancement in metabonomic analysis of UPLC–MS data sets

article

J-Resolved 1H NMR 1D-Projections for Large-Scale Metabolic Phenotyping Studies: Application to Blood Plasma Analysis.

artículo científico publicado en 2017

K-OPLS package: kernel-based orthogonal projections to latent structures for prediction and interpretation in feature space

artículo científico publicado en 2008

Kernel-based orthogonal projections to latent structures (K-OPLS)

scholarly article by Mattias Rantalainen et al published 2007 in Journal of Chemometrics

Kinetic and J-resolved statistical total correlation NMR spectroscopy approaches to structural information recovery in complex reacting mixtures: application to acyl glucuronide intramolecular transacylation reactions

artículo científico publicado en 2008

Kinetic studies on the intramolecular acyl migration of beta-1-O-acyl glucuronides: application to the glucuronides of (R)- and (S)-ketoprofen, (R)- and (S)-hydroxy-ketoprofen metabolites, and tolmetin by 1H-NMR spectroscopy

artículo científico publicado en 2005

Large-scale human metabolic phenotyping and molecular epidemiological studies via 1H NMR spectroscopy of urine: investigation of borate preservation

artículo científico publicado en 2009

Liquid chromatography coupled with high-field proton NMR for profiling human urine for endogenous compounds and drug metabolites

scientific article published on 01 August 1992

Liquid chromatography-mass spectrometry methods for urinary biomarker detection in metabonomic studies with application to nutritional studies

artículo científico publicado en 2010

Longitudinal analysis of serum oxylipin profile as a novel descriptor of the inflammatory response to surgery.

artículo científico publicado en 2017

Longitudinal metabolic and gut bacterial profiling of pregnant women with previous bariatric surgery

scientific article published on 21 January 2020

Longitudinal pharmacometabonomics for predicting patient responses to therapy: drug metabolism, toxicity and efficacy

artículo científico publicado en 2012

Low Volume in Vitro Diagnostic Proton NMR Spectroscopy of Human Blood Plasma for Lipoprotein and Metabolite Analysis: Application to SARS-CoV-2 Biomarkers

MONITORING METABOLIC DISEASE BY PROTON NMR OF URINE

artículo científico publicado en 1984

MWASTools: an R/Bioconductor package for metabolome-wide association studies.

artículo científico publicado en 2017

Magic angle spinning NMR and 1H-31P heteronuclear statistical total correlation spectroscopy of intact human gut biopsies

artículo científico publicado en 2008

Manuscript Strategy for improved characterisation of human metabolic phenotypes using a COmbined Multiblock Principal components Analysis with Statistical Spectroscopy (COMPASS)

artículo científico publicado en 2020

Mass spectrometrically detected directly coupled high performance liquid chromatography/nuclear magnetic resonance spectroscopy/mass spectrometry for the identification of xenobiotic metabolites in maize plants

article

Mechanistic aspects and novel biomarkers of responder and non-responder phenotypes in galactosamine-induced hepatitis

artículo científico publicado en 2009

Melamine-induced renal toxicity is mediated by the gut microbiota

artículo científico publicado en 2013

MetaboNetworks, an interactive Matlab-based toolbox for creating, customizing and exploring sub-networks from KEGG

artículo científico publicado en 2013

MetaboSignal: a network-based approach for topological analysis of metabotype regulation via metabolic and signaling pathways. ⬇️

artículo científico publicado en 2016

Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids

scientific article published on 18 June 2020

Metabolic Modeling in Health and Disease

artículo científico publicado en 2022

Metabolic Phenotype Modulation by Caloric Restriction in a Lifelong Dog Study

artículo científico publicado en 2013

Metabolic Phenotypes of Carotid Atherosclerotic Plaques Relate to Stroke Risk: An Exploratory Study.

artículo científico publicado en 2016

Metabolic Phenotyping Using UPLC–MS and Rapid Microbore UPLC–IM–MS: Determination of the Effect of Different Dietary Regimes on the Urinary Metabolome of the Rat

artículo científico publicado en 2020

Metabolic Phenotyping in Personalized and Public Healthcare. List of Contributors

section of a book

Metabolic Phenotyping in Personalized and Public Healthcare. Preface

preface of a book

Metabolic Phenotyping: History, Status, and Prospects

Metabolic assessment of human liver transplants from biopsy samples at the donor and recipient stages using high-resolution magic angle spinning 1H NMR spectroscopy

artículo científico publicado en 2005

Metabolic phenotype-microRNA data fusion analysis of the systemic consequences of Roux-en-Y gastric bypass surgery

artículo científico publicado en 2015

Metabolic phenotyping and systems biology approaches to understanding metabolic syndrome and fatty liver disease

artículo científico publicado en 2013

Metabolic phenotyping for discovery of urinary biomarkers of diet, xenobiotics and blood pressure in the INTERMAP Study: an overview.

artículo científico publicado en 2016

Metabolic phenotyping for monitoring surgical patients

artículo científico publicado en 2011

Metabolic phenotyping in clinical and surgical environments

artículo científico publicado en 2012

Metabolic phenotyping in health and disease

artículo científico publicado en 2008

Metabolic phenotyping of atherosclerotic plaques reveals latent associations between free cholesterol and ceramide metabolism in atherogenesis

artículo científico publicado en 2015

Metabolic phenotyping of nude and normal (Alpk:ApfCD, C57BL10J) mice

artículo científico publicado en 2006

Metabolic profiling and population screening of analgesic usage in nuclear magnetic resonance spectroscopy-based large-scale epidemiologic studies

scientific article published on July 2009

Metabolic profiling and the metabolome-wide association study: significance level for biomarker identification

artículo científico publicado en 2010

Metabolic profiling of CHO-AβPP695 cells revealed mitochondrial dysfunction prior to amyloid-β pathology and potential therapeutic effects of both PPARγ and PPARα Agonisms for Alzheimer's disease.

artículo científico publicado en 2015

Metabolic profiling of CSF: evidence that early intervention may impact on disease progression and outcome in schizophrenia

artículo científico publicado en 2006

Metabolic profiling of chronic cadmium exposure in the rat.

artículo científico publicado en 2001

Metabolic profiling of genetic disorders: a multitissue (1)H nuclear magnetic resonance spectroscopic and pattern recognition study into dystrophic tissue

artículo científico publicado en 2001

Metabolic profiling of human colorectal cancer using high-resolution magic angle spinning nuclear magnetic resonance (HR-MAS NMR) spectroscopy and gas chromatography mass spectrometry (GC/MS).

artículo científico publicado en 2009

Metabolic profiling of rodent biological fluids via 1H NMR spectroscopy using a 1 mm microlitre probe

article

Metabolic profiling of the effects of D-galactosamine in liver spheroids using (1)H NMR and MAS-NMR spectroscopy

artículo científico publicado en 2002

Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice

artículo científico publicado en 2006

Metabolic profiling strategy for discovery of nutritional biomarkers: proline betaine as a marker of citrus consumption

artículo científico publicado en 2010

Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts

artículo científico publicado en 2007

Metabolic retroconversion of trimethylamine N-oxide and the gut microbiota.

artículo científico publicado en 2018

Metabolic retroconversion of trimethylamineN-oxide and the gut microbiota

Metabolic shifts due to long-term caloric restriction revealed in nonhuman primates

artículo científico publicado en 2009

Metabolic surgery profoundly influences gut microbial-host metabolic cross-talk.

artículo científico publicado en 2011

Metabolic trajectory characterisation of xenobiotic-induced hepatotoxic lesions using statistical batch processing of NMR data

artículo científico publicado en 2002

Metabolism of 2-fluoro-4-iodoaniline in earthworm Eisenia veneta using (19)F-NMR spectroscopy, HPLC-MS, and HPLC-ICPMS ((127)I).

artículo científico publicado en 2007

Metabolism of 3-chloro-4-fluoroaniline in rat using [14C]-radiolabelling, 19F-NMR spectroscopy, HPLC-MS/MS, HPLC-ICPMS and HPLC-NMR.

artículo científico publicado en 2006

Metabolism of 4-fluoroaniline and 4-fluorobiphenyl in the earthworm Eisenia veneta characterized by high-resolution NMR spectroscopy with directly coupled HPLC-NMR and HPLC-MS.

artículo científico publicado en 2002

Metabolism of [14C]-5-chloro-1,3-benzodioxol-4-amine in male Wistar-derived rats following intraperitoneal administration

scientific article published on 01 January 2007

Metabolite changes in BT4C rat gliomas undergoing ganciclovir-thymidine kinase gene therapy-induced programmed cell death as studied by 1H NMR spectroscopy in vivo, ex vivo, and in vitro.

artículo científico publicado en 2003

Metabolome, transcriptome, and bioinformatic cis-element analyses point to HNF-4 as a central regulator of gene expression during enterocyte differentiation.

artículo científico publicado en 2006

Metabolome-wide association study identifies multiple biomarkers that discriminate north and south Chinese populations at differing risks of cardiovascular disease: INTERMAP study

artículo científico publicado en 2010

Metabolomic Strategy for the Classification and Quality Control of Phytomedicine: A Case Study of Chamomile Flower (Matricaria recutitaL.)

artículo científico publicado en 2004

Metabolomic analysis of the consequences of cadmium exposure in Silene cucubalus cell cultures via 1H NMR spectroscopy and chemometrics

artículo científico publicado en 2003

Metabonomic Investigations of Aging and Caloric Restriction in a Life-Long Dog Study

scientific article published on 06 April 2007

Metabonomic Studies on the Physiological Effects of Acute and Chronic Psychological Stress in Sprague−Dawley Rats

article

Metabonomic and microbiological analysis of the dynamic effect of vancomycin-induced gut microbiota modification in the mouse.

artículo científico publicado en 2008

Metabonomic assessment of toxicity of 4-fluoroaniline, 3,5-difluoroaniline and 2-fluoro-4-methylaniline to the earthworm Eisenia veneta (Rosa): identification of new endogenous biomarkers

artículo científico publicado en 2002

Metabonomic characterization of genetic variations in toxicological and metabolic responses using probabilistic neural networks

artículo científico publicado en 2001

Metabonomic deconvolution of embedded toxicity: application to thioacetamide hepato- and nephrotoxicity

artículo científico publicado en 2005

Metabonomic investigations in mice infected with Schistosoma mansoni: an approach for biomarker identification

scholarly article

Metabonomic investigations into hydrazine toxicity in the rat.

artículo científico publicado en 2001

Metabonomic investigations into the global biochemical sequelae of exposure to the pancreatic toxin 1-cyano-2-hydroxy-3-butene in the rat.

artículo científico publicado en 2009

Metabonomics and Metabolomics Techniques and Their Applications in Mammalian Systems

Metabonomics and its role in drug development and disease diagnosis

artículo científico publicado en 2004

Metabonomics in diabetes research

artículo científico publicado en 2007

Metabonomics in pharmaceutical R&D.

artículo científico publicado en 2007

Metabonomics in ulcerative colitis: diagnostics, biomarker identification, and insight into the pathophysiology

artículo científico publicado en 2010

Metabonomics techniques and applications to pharmaceutical research & development

artículo científico publicado en 2006

Metabonomics technologies and their applications in physiological monitoring, drug safety assessment and disease diagnosis

artículo científico publicado en 2004

Metabonomics: a platform for studying drug toxicity and gene function

artículo científico publicado en 2002

Metabonomics: systems biology in pharmaceutical research and development

artículo científico publicado en 2004

Metabotyping of long-lived mice using 1H NMR spectroscopy

artículo científico publicado en 2012

Microbial-Host Co-metabolites Are Prodromal Markers Predicting Phenotypic Heterogeneity in Behavior, Obesity, and Impaired Glucose Tolerance

artículo científico publicado en 2017

Microbial-mammalian cometabolites dominate the age-associated urinary metabolic phenotype in Taiwanese and American populations

artículo científico publicado en 2013

Microbiome inhibition of IRAK-4 by trimethylamine mediates metabolic and immune benefits in high-fat-diet-induced insulin resistance

Microbiome-host systems interactions: protective effects of propionate upon the blood-brain barrier.

artículo científico publicado en 2018

Microbiome–host systems interactions: Protective effects of propionate upon the blood–brain barrier

Mistargeting of peroxisomal EHHADH and inherited renal Fanconi's syndrome

artículo científico publicado en 2014

Modeling Longitudinal Metabonomics and Microbiota Interactions in C57BL/6 Mice Fed a High Fat Diet

artículo científico publicado en 2016

Modeling People and Populations

Modeling the effects of toxins in metabolic networks.

artículo científico publicado en 2007

Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women

artículo científico publicado en 2018

Multi-Component Metabolic Classification of Commercial Feverfew Preparations via High-Field 1H-NMR Spectroscopy and Chemometrics

artículo científico publicado en 2002

Multivariate Data Analysis Methods for NMR-based Metabolic Phenotyping in Pharmaceutical and Clinical Research

artículo científico publicado en 2015

Multivariate metabotyping of plasma predicts survival in patients with decompensated cirrhosis

artículo científico publicado en 2016

NMR Spectroscopic Windows on the Systemic Effects of SARS-CoV-2 Infection on Plasma Lipoproteins and Metabolites in Relation to Circulating Cytokines

NMR Spectroscopic and Theoretical Chemistry Studies on the Internal Acyl Migration Reactions of the 1-O-Acyl-β-d-glucopyranuronate Conjugates of 2-, 3-, and 4-(Trifluoromethyl)benzoic Acids

article

NMR Spectroscopy of Biofluids

article

NMR and HPLC-NMR spectroscopic studies of futile deacetylation in paracetamol metabolites in rat and man

article

NMR and QSAR studies on the transacylation reactivity of model 1beta-O-acyl glucuronides. I: design, synthesis and degradation rate measurement

artículo científico publicado en 2004

NMR and pattern recognition studies on liver extracts and intact livers from rats treated with alpha-naphthylisothiocyanate

artículo científico publicado en 2002

NMR spectroscopic studies of the transacylation reactivity of ibuprofen 1-beta-O-acyl glucuronide

artículo científico publicado en 2006

NMR spectroscopic studies on the in vitro acyl glucuronide migration kinetics of Ibuprofen ((+/-)-(R,S)-2-(4-isobutylphenyl) propanoic acid), its metabolites, and analogues

artículo científico publicado en 2007

NMR spectroscopic studies on the metabolism and futile deacetylation of phenacetin in the rat

artículo científico publicado en 1997

NMR spectroscopic-based metabonomic studies of urinary metabolite variation in acclimatizing germ-free rats

artículo científico publicado en 2003

NMR-based metabolic profiling and metabonomic approaches to problems in molecular toxicology

artículo científico publicado en 2008

NMR-based metabolic profiling identifies biomarkers of liver regeneration following partial hepatectomy in the rat.

artículo científico publicado en 2010

NMR-based metabonomic approaches for evaluating physiological influences on biofluid composition

artículo científico publicado en 2005

NMR-based metabonomic studies on the biochemical effects of commonly used drug carrier vehicles in the rat.

artículo científico publicado en 2002

NMR-based metabonomic studies on the biochemical effects of epicatechin in the rat.

artículo científico publicado en 2003

NMR-based metabonomic toxicity classification: hierarchical cluster analysis and k-nearest-neighbour approaches

article

NMR-monitored solid-phase extraction of phenolphthalein glucuronide on phenylboronic acid and C18 bonded phases

scientific article published on 01 January 1991

Neonatal environment exerts a sustained influence on the development of the intestinal microbiota and metabolic phenotype

artículo científico publicado en 2015

Nephrocalcinosis (enamel renal syndrome) caused by autosomal recessive FAM20A mutations ⬇️

artículo científico publicado en 2012

Network Mapping of Molecular Biomarkers Influencing Radiation Response in Rectal Cancer

scientific article published on 10 February 2019

Network analysis of mass spectrometry imaging data from colorectal cancer identifies key metabolites common to metastatic development

article

Neurogenesis and prolongevity signaling in young germ-free mice transplanted with the gut microbiota of old mice

scientific article published on 01 November 2019

Non-linear modeling of 1H NMR metabonomic data using kernel-based orthogonal projections to latent structures optimized by simulated annealing

artículo científico publicado en 2011

Novel application of reversed-phase UPLC-oaTOF-MS for lipid analysis in complex biological mixtures: a new tool for lipidomics.

artículo científico publicado en 2007

Nuclear Magnetic Resonance Spectroscopic and Principal Components Analysis Investigations into Biochemical Effects of Three Model Hepatotoxins

article

Nuclear Magnetic Resonance and High-Performance Liquid Chromatography-Nuclear Magnetic Resonance Studies on the Toxicity and Metabolism of Ifosfamide

article

Nutriome-metabolome relationships provide insights into dietary intake and metabolism

scientific article published on 22 June 2020

Nutritional modulation of the metabonome: applications of metabolic phenotyping in translational nutritional research

artículo científico publicado en 2014

OPLS discriminant analysis: combining the strengths of PLS-DA and SIMCA classification

article

Obesity and Cage Environment Modulate Metabolism in the Zucker Rat: A Multiple Biological Matrix Approach to Characterizing Metabolic Phenomena

scientific article published on 18 April 2019

Objective assessment of dietary patterns by use of metabolic phenotyping: a randomised, controlled, crossover trial

artículo científico publicado en 2017

Objective set of criteria for optimization of sample preparation procedures for ultra-high throughput untargeted blood plasma lipid profiling by ultra performance liquid chromatography-mass spectrometry

artículo científico publicado en 2014

Opening up the "Black Box": metabolic phenotyping and metabolome-wide association studies in epidemiology

artículo científico publicado en 2010

Optimization and Application of Direct Infusion Nanoelectrospray HRMS Method for Large-Scale Urinary Metabolic Phenotyping in Molecular Epidemiology

artículo científico publicado en 2017

Optimization and evaluation of metabolite extraction protocols for untargeted metabolic profiling of liver samples by UPLC-MS.

artículo científico publicado en 2010

Optimization of human plasma 1H NMR spectroscopic data processing for high-throughput metabolic phenotyping studies and detection of insulin resistance related to type 2 diabetes

artículo científico publicado en 2008

Optimized Phenotypic Biomarker Discovery and Confounder Elimination via Covariate-Adjusted Projection to Latent Structures from Metabolic Spectroscopy Data

artículo científico publicado en 2018

Optimized Preprocessing of Ultra-Performance Liquid Chromatography/Mass Spectrometry Urinary Metabolic Profiles for Improved Information Recovery

article

Optimized Sample Handling Strategy for Metabolic Profiling of Human Feces.

artículo científico publicado en 2016

Overview of the Nomenclature and Network of Contributors to the Development of Bioreactors for Human Gut Simulation Using Bibliometric Tools: A Fragmented Landscape

artículo científico publicado en 2022

Panorganismal gut microbiome-host metabolic crosstalk

artículo científico publicado en 2009

Panorganismal metabolic response modeling of an experimental Echinostoma caproni infection in the mouse

artículo científico publicado en 2009

Paracetamol metabolism, hepatotoxicity, biomarkers and therapeutic interventions: a perspective

scientific article published on 06 March 2018

Pharmaco-metabonomic phenotyping and personalized drug treatment

artículo científico publicado en 2006

Pharmacometabonomic Characterization of Xenobiotic and Endogenous Metabolic Phenotypes That Account for Inter-individual Variation in Isoniazid-Induced Toxicological Response

article

Pharmacometabonomic Investigation of Dynamic Metabolic Phenotypes Associated with Variability in Response to Galactosamine Hepatotoxicity

article

Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism

artículo científico publicado en 2009

Pharmacometabonomics and Predictive Metabonomics

Pharmacometabonomics as an effector for personalized medicine.

artículo científico publicado en 2011

Phenotyping the Patient Journey

Phylometabonomic patterns of adaptation to high fat diet feeding in inbred mice

artículo científico publicado en 2008

Physiological variation in metabolic phenotyping and functional genomic studies: use of orthogonal signal correction and PLS-DA.

artículo científico publicado en 2002

Piecewise multivariate modelling of sequential metabolic profiling data

artículo científico publicado en 2008

Power Analysis and Sample Size Determination in Metabolic Phenotyping

artículo científico publicado en 2016

Precision High-Throughput Proton NMR Spectroscopy of Human Urine, Serum, and Plasma for Large-Scale Metabolic Phenotyping

article

Prediction and classification of drug toxicity using probabilistic modeling of temporal metabolic data: the consortium on metabonomic toxicology screening approach

artículo científico publicado en 2007

Prediction of urinary sulphate and glucuronide conjugate excretion for substituted phenols in the rat using quantitative structure-metabolism relationships.

artículo científico publicado en 1995

Preface

Preparing for Precision Medicine

article

Probing latent biomarker signatures and in vivo pathway activity in experimental disease states via statistical total correlation spectroscopy (STOCSY) of biofluids: application to HgCl2 toxicity.

artículo científico publicado en 2006

Probing molecular dynamics in chromatographic systems using high-resolution 1H magic-angle-spinning NMR spectroscopy: interaction between p-Xylene and C18-bonded silica

artículo científico publicado en 2004

Probiotic modulation of symbiotic gut microbial-host metabolic interactions in a humanized microbiome mouse model

artículo científico publicado en 2008

Proton MRS of human prostatic fluid: Correlations between citrate, spermine, andmyo-inositol levels and changes with disease

artículo científico publicado en 1997

Proton NMR analysis of plasma from renal failure patients: Evaluation of sample preparation and spectral-editing methods

artículo científico publicado en 1990

Proton NMR monitoring of the onset and recovery of experimental renal damage

article

Proton NMR spectroscopic studies on the metabolism and biochemical effects of hydrazine in vivo

artículo científico publicado en 1992

Proton NMR spectroscopy of bile for monitoring the excretion of endogenous and xenobiotic metabolites: Application to para-aminophenol

artículo científico publicado en 1989

Proton NMR studies on the effects of uranyl nitrate on the biochemical composition of rat urine and plasma

artículo científico publicado en 1990

Proton magnetic resonance spectroscopy of human urine: Excretion of 1-(3'-carboxypropyl)-3,7-dimethylxanthine by man after dosing with oxpentifylline.

artículo científico publicado en 1987

Proton nuclear magnetic resonance of urine and bile from paracetamol dosed rats

artículo científico publicado en 1990

Publisher Correction: Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women

artículo científico publicado en 2018

Quantifying Diet-Induced Metabolic Changes of the Human Gut Microbiome.

artículo científico publicado en 2015

Quantitation in gradient high performance liquid chromatography/inductively coupled mass spectrometry investigated using diclofenac and chlorpromazine

artículo científico publicado en 2002

Quantitative In-Vitro Diagnostic NMR Spectroscopy for Lipoprotein and Metabolite Measurements in Plasma and Serum: Recommendations for Analytical Artefact Minimization with Special Reference to COVID-19/SARS-CoV-2 Samples

scientific article published on 27 August 2020

Quantitative Investigation of Probabilistic Spectral Processing Methods Using Simulated NMR Data

Quantitative Lipoprotein Subclass and Low Molecular Weight Metabolite Analysis in Human Serum and Plasma by 1H NMR Spectroscopy in a Multilaboratory Trial

scientific article published on 27 September 2018

Quantitative UPLC-MS/MS analysis of the gut microbial co-metabolites phenylacetylglutamine, 4-cresyl sulphate and hippurate in human urine: INTERMAP Study

artículo científico publicado en 2012

Quantitative structure-metabolism relationships for substituted benzoic acids in the rat. Computational chemistry, NMR spectroscopy and pattern recognition studies.

artículo científico publicado en 1992

Quantitative structure-toxicity relationships for halogenated substituted-benzenes to Vibrio fischeri, using atom-based semi-empirical molecular-orbital descriptors.

artículo científico publicado en 1999

Quantitative studies on the urinary metabolic fate of 2-chloro-4-trifluoromethylaniline in the rat using 19F-NMR spectroscopy and directly coupled HPLCNMR-MS

scientific article published on 01 January 1999

Quantitative urinalysis of the mercapturic acid conjugates of allyl formate using high-resolution NMR spectroscopy

artículo científico publicado en 2005

Raised transaminase activity of blood plasma from rats with experimentally-induced kidney damage detected by spin-echo 1H-NMR spectroscopy

artículo científico publicado en 1993

Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics

artículo científico publicado en 2002

Rapid diagnosis and staging of colorectal cancer via high-resolution magic angle spinning nuclear magnetic resonance (HR-MAS NMR) spectroscopy of intact tissue biopsies

artículo científico publicado en 2014

Recent advances in high-resolution NMR spectroscopic methods in bioanalytical chemistry

Recovery of underwater resonances by magnetization transferred NMR spectroscopy (RECUR-NMR).

artículo científico publicado en 2001

Recursive segment-wise peak alignment of biological (1)h NMR spectra for improved metabolic biomarker recovery

artículo científico publicado en 2009

Reduced plasma levels of small HDL particles transporting fibrinolytic proteins in pulmonary arterial hypertension

artículo científico publicado en 2018

Relation of raw and cooked vegetable consumption to blood pressure: the INTERMAP Study

artículo científico publicado en 2013

Relationship between vaginal microbial dysbiosis, inflammation, and pregnancy outcomes in cervical cerclage

artículo científico publicado en 2016

Reply

Response to Comment on “Optimized Preprocessing of Ultra-Performance Liquid Chromatography/Mass Spectrometry Urinary Metabolic Profiles for Improved Information Recovery”

artículo científico publicado en 2011

Reviewers peering from under a pile of 'omics' data.

artículo científico publicado en 2006

Robust algorithms for automated chemical shift calibration of 1D 1H NMR spectra of blood serum

artículo científico publicado en 2008

Robust data processing and normalization strategy for MALDI mass spectrometric imaging

artículo científico publicado en 2012

SPUTNIK: an R package for filtering of spatially related peaks in mass spectrometry imaging data

artículo científico publicado en 2019

Sample classification based on Bayesian spectral decomposition of metabonomic NMR data sets

artículo científico publicado en 2004

Scaling and normalization effects in NMR spectroscopic metabonomic data sets

artículo científico publicado en 2006

Selective Inverse-Detected Long-Range HeteronuclearJ-Resolved NMR Spectroscopy and Its Application to the Measurement of3JCH

Self-modeling curve resolution recovery of temporal metabolite signal modulation in NMR spectroscopic data sets: application to a life-long caloric restriction study in dogs

artículo científico publicado en 2008

Seminal oligouridinosis: low uridine secretion as a biomarker for infertility in spinal neurotrauma

artículo científico publicado en 2008

Serum metabolic signatures of coronary and carotid atherosclerosis and subsequent cardiovascular disease

artículo científico publicado en 2019

Sex-dependent effects on gut microbiota regulate hepatic carcinogenic outcomes

artículo científico publicado en 2017

Sexual dimorphism in urinary metabolite profiles of Han Wistar rats revealed by nuclear-magnetic-resonance-based metabonomics

artículo científico publicado en 2005

So what's the deal with metabonomics?

artículo científico publicado en 2003

Solid phase extraction chromatography and NMR spectroscopy (SPEC-NMR) for the rapid identification of drug metabolites in urine.

artículo científico publicado en 1988

Spatially resolved metabolic phenotyping of breast cancer by desorption electrospray ionization mass spectrometry

artículo científico publicado en 2015

Species variation in the fecal metabolome gives insight into differential gastrointestinal function

artículo científico publicado en 2007

Spectral editing and pattern recognition methods applied to high-resolution magic-angle spinning 1H nuclear magnetic resonance spectroscopy of liver tissues

artículo científico publicado en 2003

Spectral profiles of cultured neuronal and glial cells derived from HRMAS (1)H NMR spectroscopy

artículo científico publicado en 2002

Spectroscopic and statistical techniques for information recovery in metabonomics and metabolomics

scientific article published on January 2008

Stability and Robustness of Human Metabolic Phenotypes in Response to Sequential Food Challenges

article

Statistical Correlation and Projection Methods for Improved Information Recovery from Diffusion-Edited NMR Spectra of Biological Samples

article

Statistical HOmogeneous Cluster SpectroscopY (SHOCSY): an optimized statistical approach for clustering of ¹H NMR spectral data to reduce interference and enhance robust biomarkers selection

artículo científico publicado en 2014

Statistical experimental design and partial least squares regression analysis of biofluid metabonomic NMR and clinical chemistry data for screening of adverse drug effects

article

Statistical heterospectroscopy, an approach to the integrated analysis of NMR and UPLC-MS data sets: application in metabonomic toxicology studies

artículo científico publicado en 2006

Statistical search space reduction and two-dimensional data display approaches for UPLC-MS in biomarker discovery and pathway analysis

artículo científico publicado en 2006

Statistical spectroscopic tools for biomarker discovery and systems medicine

artículo científico

Statistical total correlation spectroscopy editing of 1H NMR spectra of biofluids: application to drug metabolite profile identification and enhanced information recovery.

artículo científico publicado en 2009

Statistical total correlation spectroscopy scaling for enhancement of metabolic information recovery in biological NMR spectra

artículo científico publicado en 2011

Statistical total correlation spectroscopy: an exploratory approach for latent biomarker identification from metabolic 1H NMR data sets

artículo científico publicado en 2005

Statistically integrated metabonomic-proteomic studies on a human prostate cancer xenograft model in mice

artículo científico publicado en 2006

Structural shifts of gut microbiota as surrogate endpoints for monitoring host health changes induced by carcinogen exposure

artículo científico publicado en 2010

Structure-metabolism relationships of substituted anilines: prediction of N-acetylation and N-oxanilic acid formation using computational chemistry

artículo científico publicado en 2002

Studies of the biochemical toxicology of uranyl nitrate in the rat

artículo científico publicado en 1994

Studies on the biochemical effects of the aldose reductase inhibitor 2,7-difluorospirofluorene-9,5′-imidazolidine-2′,4′-dione (Al 1576, HOE 843)

artículo científico publicado en 1992

Studies on the comparative toxicity of S-(1,2-dichlorovinyl)-L-cysteine, S-(1,2-dichlorovinyl)-L-homocysteine and 1,1,2-trichloro-3,3,3-trifluoro-1-propene in the Fischer 344 rat

article

Studies on the effects of L(alpha S,5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (AT-125) on 4-aminophenol-induced nephrotoxicity in the Fischer 344 rat.

artículo científico publicado en 1993

Studies on the metabolism of fluorinated xenobiotics in the rat using 19F-NMR and 1H-NMR spectroscopy

scientific article published on 01 January 1990

Studies on the relationship between acute testicular damage and urinary and plasma creatine concentration

artículo científico publicado en 1990

Subset Optimization by Reference Matching (STORM): An Optimized Statistical Approach for Recovery of Metabolic Biomarker Structural Information from 1H NMR Spectra of Biofluids

article

Subtle metabolic and liver gene transcriptional changes underlie diet-induced fatty liver susceptibility in insulin-resistant mice

article

Summary recommendations for standardization and reporting of metabolic analyses

artículo científico publicado en 2005

Surgical systems biology and personalized longitudinal phenotyping in critical care

Susceptibility of Human Metabolic Phenotypes to Dietary Modulation

article

Symbiotic bacterial metabolites regulate gastrointestinal barrier function via the xenobiotic sensor PXR and Toll-like receptor 4.

artículo científico publicado en 2014

Symbiotic gut microbes modulate human metabolic phenotypes

artículo científico publicado en 2008

Synthesis of a series of phenylacetic acid 1-β-O-acyl glucosides and comparison of their acyl migration and hydrolysis kinetics with the corresponding acyl glucuronides

artículo científico publicado en 2010

Synthesis, transacylation kinetics and computational chemistry of a set of arylacetic acid 1beta-O-acyl glucuronides.

artículo científico publicado en 2009

System level metabolic effects of a Schistosoma japonicum infection in the Syrian hamster

artículo científico publicado en 2005

Systematic Isolation and Structure Elucidation of Urinary Metabolites Optimized for the Analytical-Scale Molecular Profiling Laboratory

artículo científico publicado en 2019

Systematic evaluation of extraction methods for multiplatform-based metabotyping: application to the Fasciola hepatica metabolome

artículo científico publicado en 2012

Systemic Characterization of an Obese Phenotype in the Zucker Rat Model Defining Metabolic Axes of Energy Metabolism and Host-Microbial Interactions.

artículo científico publicado en 2016

Systemic gut microbial modulation of bile acid metabolism in host tissue compartments

artículo científico publicado en 2010

Systemic multicompartmental effects of the gut microbiome on mouse metabolic phenotypes.

artículo científico publicado en 2008

Systems Genetics of Hepatic Metabolome Reveals Octopamine as a Target for Non-Alcoholic Fatty Liver Disease Treatment

article

Systems Toxicology: Integrated Genomic, Proteomic and Metabonomic Analysis of Methapyrilene Induced Hepatotoxicity in the Rat

article

Systems biology to battle vascular disease

scientific article published on 03 February 2010

Systems biology: Metabonomics

artículo científico publicado en 2008

Systems parasitology: effects of Fasciola hepatica on the neurochemical profile in the rat brain

artículo científico publicado en 2010

Systems toxicology: modelling biomarkers of glutathione homeostasis and paracetamol metabolism

artículo científico

Targeting the human genome-microbiome axis for drug discovery: inspirations from global systems biology and traditional Chinese medicine.

artículo científico

Technical and Biological Variation in UPLC−MS-Based Untargeted Metabolic Profiling of Liver Extracts: Application in an Experimental Toxicity Study on Galactosamine

article

Temporal metabonomic modeling of l-arginine-induced exocrine pancreatitis

artículo científico publicado en 2008

The Consortium for Metabonomic Toxicology (COMET): aims, activities and achievements

artículo científico publicado en 2005

The Development of a Metabonomic-Based Drug Safety Testing Paradigm

article

The Footprints of Gut Microbial–Mammalian Co-Metabolism

artículo científico publicado en 2011

The Metabolic Window into Systems Biology

The Microbial Metabolite 4-Cresol Improves Glucose Homeostasis and Enhances β-Cell Function

The biochemical profile of rat testicular tissue as measured by magic angle spinning 1H NMR spectroscopy.

artículo científico publicado en 2000

The challenges of modeling mammalian biocomplexity

artículo científico publicado en 2004

The comparative distribution of zinc, cadmium and mercury in selected tissues of the herring gull (Larus argentatus) ⬇️

artículo científico publicado el 1 de enero de 1981

The comparison of plasma deproteinization methods for the detection of low-molecular-weight metabolites by (1)H nuclear magnetic resonance spectroscopy

artículo científico publicado en 2002

The effects of kisspeptin on β-cell function, serum metabolites and appetite in humans

artículo científico publicado en 2018

The emergent role of metabolic phenotyping in dynamic patient stratification

artículo científico publicado en 2014

The evolution of partial least squares models and related chemometric approaches in metabonomics and metabolic phenotyping

article

The fox in the box: acoustic deterrent and simulated predator disturbance to reduce problematic bird accumulations

artículo científico publicado en 2022

The gut microbiota as a target for improved surgical outcome and improved patient care

artículo científico publicado en 2009

The gut microbiota influences skeletal muscle mass and function in mice

scientific article published on 01 July 2019

The human gut microbiome: implications for future health care

scientific article published on August 2008

The identification of novel biomarkers of renal toxicity using automatic data reduction techniques and PCA of proton NMR spectra of urine

article

The influence of EDTA and citrate anticoagulant addition to human plasma on information recovery from NMR-based metabolic profiling studies

artículo científico publicado en 2009

The influence of pharmacogenetics on fatty liver disease in the wistar and kyoto rats: a combined transcriptomic and metabonomic study

scientific journal article

The initial pathogenesis of cadmium induced renal toxicity

scholarly article by Julian L. Griffin published in July 2000

The interaction between vaginal microbiota, cervical length, and vaginal progesterone treatment for preterm birth risk

artículo científico publicado en 2017

The mechanism of galactosamine toxicity revisited; a metabonomic study.

artículo científico publicado en 2007

The metabolic fate and effects of 2-Bromophenol in male Sprague-Dawley rats

artículo científico publicado en 2019

The metabolism and excretion of [14C] 2- and 4-chlorobenzoic acids in the rat

artículo científico publicado en 2000

The metabolism of 2-trifluormethylaniline and its acetanilide in the rat by 19F NMR monitored enzyme hydrolysis and 1H/19F HPLC-NMR spectroscopy

artículo científico publicado en 2003

The metabolism of 4-trifluoromethoxyaniline and [13C]-4-trifluoromethoxyacetanilide in the rat: detection and identification of metabolites excreted in the urine by NMR and HPLC-NMR.

artículo científico publicado en 2002

The metabolite profiles of the obese population are gender-dependent

artículo científico publicado en 2014

The metabolome-wide association study: a new look at human disease risk factors.

artículo científico publicado en 2008

The nPYc-Toolbox, a Python module for the pre-processing, quality-control and analysis of metabolic profiling datasets

scientific article published on 01 December 2019

The pathophysiology of human obstructive cholestasis is mimicked in cholestatic Gold Syrian hamsters.

artículo científico publicado en 2017

The potential of 19F NMR spectroscopy for rapid screening of cell cultures for models of mammalian drug metabolism

article

The promise of metabolic phenotyping in gastroenterology and hepatology

artículo científico publicado en 2015

The role of gut microbiota in drug response.

artículo científico publicado en 2009

Therapeutic modulation of microbiota-host metabolic interactions.

artículo científico

Top-down systems biology integration of conditional prebiotic modulated transgenomic interactions in a humanized microbiome mouse model

artículo científico publicado en 2008

Top-down systems biology modeling of host metabotype-microbiome associations in obese rodents

artículo científico publicado en 2009

Topics in Xenobiochemistry: Do metabolic pathways exist for xenobiotics? The micro-metabolism hypothesis ⬇️

artículo científico publicado el 1 de septiembre de 2003

Topographical variation in metabolic signatures of human gastrointestinal biopsies revealed by high-resolution magic-angle spinning 1H NMR spectroscopy.

artículo científico publicado en 2007

Topographical variation in murine intestinal metabolic profiles in relation to microbiome speciation and functional ecological activity.

artículo científico publicado en 2009

Topological analysis of metabolic networks integrating co-segregating transcriptomes and metabolomes in type 2 diabetic rat congenic series

artículo científico publicado en 2016

Toxicity classification from metabonomic data using a density superposition approach: ‘CLOUDS’

article

Transgenomic metabolic interactions in a mouse disease model: interactions of Trichinella spiralis infection with dietary Lactobacillus paracasei supplementation.

artículo científico publicado en 2006

Translational utility of a hierarchical classification strategy in biomolecular data analytics.

artículo científico publicado en 2017

UPLC-MS, HPLC-radiometric, and NMR-spectroscopic studies on the metabolic fate of 3-fluoro-[U-14C]-aniline in the bile-cannulated rat.

artículo científico publicado en 2010

UPLC/MS(E); a new approach for generating molecular fragment information for biomarker structure elucidation

artículo científico publicado en 2006

UPLC/MSE; a new approach for generating molecular fragment information for biomarker structure elucidation

article

Ultra high field NMR spectroscopic studies on human seminal fluid, seminal vesicle and prostatic secretions

artículo científico publicado en 1994

Ultra performance liquid chromatography-mass spectrometry profiling of bile acid metabolites in biofluids: application to experimental toxicology studies.

artículo científico publicado en 2010

Ultra-Performance Liquid Chromatography-High-Resolution Mass Spectrometry and Direct Infusion-High-Resolution Mass Spectrometry for Combined Exploratory and Targeted Metabolic Profiling of Human Urine

artículo científico publicado en 2018

Ultrahigh-Performance Liquid Chromatography Tandem Mass Spectrometry with Electrospray Ionization Quantification of Tryptophan Metabolites and Markers of Gut Health in Serum and Plasma-Application to Clinical and Epidemiology Cohorts

article

Understanding 'Global' Systems Biology: Metabonomics and the Continuum of Metabolism

Understanding the role of gut microbiome-host metabolic signal disruption in health and disease

scientific article published on 22 June 2011

Unmet Medical Needs

Untargeted Mass Spectrometry Lipidomics identifies correlation between serum sphingomyelins and plasma cholesterol

artículo científico publicado en 2019

Untargeted Metabolome Quantitative Trait Locus Mapping Associates Variation in Urine Glycerate to Mutant Glycerate Kinase

article

Untargeted UPLC-MS profiling pipeline to expand tissue metabolome coverage: application to cardiovascular disease

artículo científico publicado en 2015

Urinary Metabolic Phenotyping of Women with Lower Urinary Tract Symptoms.

artículo científico publicado en 2017

Urinary metabolic phenotyping differentiates children with autism from their unaffected siblings and age-matched controls

artículo científico publicado en 2010

Urinary metabolic phenotyping for Alzheimer’s disease

artículo científico publicado en 2020

Urinary metabolic phenotyping the slc26a6 (chloride-oxalate exchanger) null mouse model

artículo científico publicado en 2012

Urinary metabolic signatures of human adiposity

artículo científico publicado en 2015

Urinary metabolites of 2-bromoethanamine identified by stable isotope labelling: evidence for carbamoylation and glutathione conjugation

article

Urinary phenotyping indicates weight loss-independent metabolic effects of Roux-en-Y gastric bypass in mice.

artículo científico publicado en 2013

Uroscopy in the 21st century: high-field NMR spectroscopy.

artículo científico publicado en 1997

Use of an Atmospheric Solids Analysis Probe (ASAP) for High Throughput Screening of Biological Fluids: Preliminary Applications on Urine and Bile

article

Use of high-field nuclear magnetic resonance spectroscopy for the analysis of biological fluids

Use of metabonomics to identify impaired fatty acid metabolism as the mechanism of a drug-induced toxicity

artículo científico publicado en 2004

Use of relaxation-edited one-dimensional and two dimensional nuclear magnetic resonance spectroscopy to improve detection of small metabolites in blood plasma

artículo científico publicado en 2004

Use of1H NMR-determined diffusion coefficients to characterize lipoprotein fractions in human blood plasma

article

Vaginal dysbiosis increases risk of preterm fetal membrane rupture, neonatal sepsis and is exacerbated by erythromycin

artículo científico publicado en 2018

Variation in Antibiotic-Induced Microbial Recolonization Impacts on the Host Metabolic Phenotypes of Rats

artículo científico publicado en 2011

Variation in Gut Microbiota Strongly Influences Individual Rodent Phenotypes

artículo científico publicado en 2005

Virtual Chromatographic Resolution Enhancement in Cryoflow LC−NMR Experiments via Statistical Total Correlation Spectroscopy

scientific article published on 30 March 2007

Want to Publish in JPR ? This Is What You Need to Know!

artículo científico publicado en 2022

Weaning diet induces sustained metabolic phenotype shift in the pig and influences host response toBifidobacterium lactisNCC2818

article

XCMS-MRM and METLIN-MRM: a cloud library and public resource for targeted analysis of small molecules

artículo científico publicado en 2018

mQTL.NMR: an integrated suite for genetic mapping of quantitative variations of (1)H NMR-based metabolic profiles

artículo científico publicado en 2015

pJRES Binning Algorithm (JBA): a new method to facilitate the recovery of metabolic information from pJRES 1H NMR spectra

article

¹H NMR-based metabonomics for investigating diabetes

scientific article published on July 2009

Lista de obras de Jeremy K. Nicholson

-Omics dreams of personalized healthcare

19F NMR spectroscopic investigation into the absorption and metabolism of 3-trifluoromethylaniline in Eisenia veneta

19F and 1H magnetic resonance strategies for metabolic studies on fluorinated xenobiotics: Application to flurbiprofen [2-(2-fluoro-4-biphenylyl)propionic acid]

19F-NMR and directly coupled 19F/1H-HPLC-NMR spectroscopic investigations of the metabolism of the model ecotoxin 3-trifluoromethylaniline in the earthworm species Eisenia veneta

1H HR-MAS NMR spectroscopy of tumor-induced local metabolic "field-effects" enables colorectal cancer staging and prognostication

1H NMR Global Metabolic Phenotyping of Acute Pancreatitis in the Emergency Unit

1H NMR and UPLC-MS(E) statistical heterospectroscopy: characterization of drug metabolites (xenometabolome) in epidemiological studies

1H NMR and UPLC-MSEStatistical Heterospectroscopy: Characterization of Drug Metabolites (Xenometabolome) in Epidemiological Studies

1H NMR spectroscopic and histopathological studies on propyleneimine-induced renal papillary necrosis in the rat and the multimammate desert mouse (Mastomys natalensis).

1H NMR spectroscopy-based interventional metabolic phenotyping: a cohort study of rheumatoid arthritis patients.

1H and 2H NMR spectroscopic studies on the metabolism and biochemical effects of 2-bromoethanamine in the rat

1H-NMR spectroscopy of biofluids and the investigation of xenobiotic-induced changes in liver biochemistry

2-Furoylglycine as a Candidate Biomarker of Coffee Consumption

2.7.5. HPLC/NMR and related hyphenated NMR methods

600 MHz 1H-NMR spectroscopy of human cerebrospinal fluid: effects of sample manipulation and assignment of resonances

750 MHz 1H NMR spectroscopy characterisation of the complex metabolic pattern of urine from patients with inborn errors of metabolism: 2-hydroxyglutaric aciduria and maple syrup urine disease

750 MHz 1H-NMR spectroscopy of human blood plasma

750 MHz HPLC-NMR spectroscopic identification of rat microsomal metabolites of phenoxypyridines

750 MHz HPLC−NMR Spectroscopic Studies on the Separation and Characterization of the Positional Isomers of the Glucuronides of 6,11-Dihydro-11- oxodibenz[b,e]oxepin-2-acetic Acid

750-MHz directly coupled HPLC-NMR: Application for the sequential characterization of the positional isomers and anomers of 2-, 3-, and 4-fluorobenzoic acid glucuronides in equilibrium mixtures

A Metabolic Entropy Approach for Measurements of Systemic Metabolic Disruptions in Patho-Physiological States

A Metabolite Array Technology for Precision Medicine

A QSAR investigation of dermal and respiratory chemical sensitizers based on computational chemistry properties

A Unified Conceptual Framework for Metabolic Phenotyping in Diagnosis and Prognosis

A comparison of collision cross section values obtained via travelling wave ion mobility-mass spectrometry and ultra high performance liquid chromatography-ion mobility-mass spectrometry: Application to the characterisation of metabolites in rat uri

A comparison of quantitative NMR and radiolabelling studies of the metabolism and excretion of Statil (3-(4-bromo-2-fluorobenzyl)-4-oxo-3H-phthalazin-1-ylacetic acid) in the rat.

A comparison of self-reported analgesic use and detection of urinary ibuprofen and acetaminophen metabolites by means of metabonomics: the INTERMAP Study

A genome-wide metabolic QTL analysis in Europeans implicates two loci shaped by recent positive selection

A metabolic phenotyping approach to understanding relationships between metabolic syndrome and breast tumour responses to chemotherapy

A metabolic system-wide characterisation of the pig: a model for human physiology

A metabonomic investigation of hepatotoxicity using diffusion-edited 1H NMR spectroscopy of blood serum

A metabonomic strategy for the detection of the metabolic effects of chamomile (Matricaria recutita L.) ingestion

A multiplexed targeted assay for high-throughput quantitative analysis of serum methylamines by ultra performance liquid chromatography coupled to high resolution mass spectrometry

A novel LC-MS approach for the detection of metabolites in DMPK studies.

A novel methodology for in vivo endoscopic phenotyping of colorectal cancer based on real-time analysis of the mucosal lipidome: a prospective observational study of the iKnife

A pattern recognition approach to the comparison of PMR and clinical chemical data for classification of nephrotoxicity.

A prospective analysis of mucosal microbiome-metabonome interactions in colorectal cancer using a combined MAS 1HNMR and metataxonomic strategy

A prospective cohort analysis of gut microbial co-metabolism in Alaska Native and rural African people at high and low risk of colorectal cancer

A rapid simple approach to screening pharmaceutical products using ultra-performance LC coupled to time-of-flight mass spectrometry and pattern recognition

A simultaneous exploratory and quantitative amino acid and biogenic amine metabolic profiling platform for rapid disease phenotyping via UPLC-QToF-MS

A study of metabolic compartmentation in the rat heart and cardiac mitochondria using high-resolution magic angle spinning 1H NMR spectroscopy.

A study of the metabolism of dimethylformamide in the rat by high resolution proton NMR spectroscopy

A top-down systems biology view of microbiome-mammalian metabolic interactions in a mouse model

A two-way interaction between methotrexate and the gut microbiota of male Sprague Dawley rats

A validated UPLC-MS/MS assay for the quantification of amino acids and biogenic amines in rat urine

APPLICATION OF HIGH RESOLUTION H-NMR SPECTROSCOPY TO THE DETECTION OF PENICILLAMINE AND ITS METABOLITES IN HUMAN URINE

Abnormal lipid profile of dystrophic cardiac tissue as demonstrated by one- and two-dimensional magic-angle spinning (1)H NMR spectroscopy

Acute renal failure following accidental cutaneous absorption of phenol: application of NMR urinalysis to monitor the disease process.

Addressing the challenge of limited sample volumes inin vitrostudies with capillary-scale microfluidic LC–MS/MS

Age and microenvironment outweigh genetic influence on the Zucker rat microbiome

An Analytical Pipeline for Quantitative Characterization of Dietary Intake: Application To Assess Grape Intake

An NMR study of the metabolic fate of 2-, 3- and 4-fluorobenzyl alcohols in the rat: detection of N-acetylcysteinyl conjugates as minor metabolites in urine

An NMR-based metabonomic approach to investigate the biochemical consequences of genetic strain differences: application to the C57BL10J and Alpk:ApfCD mouse

An NMR-based metabonomic approach to the investigation of coelomic fluid biochemistry in earthworms under toxic stress.

An hypothesis for a mechanism underlying hepatotoxin-induced hypercreatinuria

An integrated ceramic, micro-fluidic device for the LC/MS/MS analysis of pharmaceuticals in plasma

An integrated metabonomic approach to describe temporal metabolic disregulation induced in the rat by the model hepatotoxin allyl formate.

An integrated metabonomic investigation of acetaminophen toxicity in the mouse using NMR spectroscopy

An integrated reverse functional genomic and metabolic approach to understanding orotic acid-induced fatty liver

Analysis of biological fluids using 600 MHz proton NMR spectroscopy: Application of homonuclear two-dimensional J-resolved spectroscopy to urine and blood plasma for spectral simplification and assignment

Analysis of polar urinary metabolites for metabolic phenotyping using supercritical fluid chromatography and mass spectrometry

Analysis of time-related metabolic fluctuations induced by ethionine in the rat.

Analytic properties of statistical total correlation spectroscopy based information recovery in 1H NMR metabolic data sets

Analytical reproducibility in (1)H NMR-based metabonomic urinalysis

Analytical technologies for metabonomics and metabolomics, and multi-omic information recovery

Application of (1)H- and (19)F-NMR spectroscopy in the investigation of the urinary and biliary excretion of 3,5-, 2,4-ditrifluoromethylbenzoic and pentafluorobenzoic acids in rat.

Application of Directly Coupled HPLC NMR to Separation and Characterization of Lipoproteins from Human Serum

Application of Directly Coupled HPLC-NMR-MS/MS to the Identification of Metabolites of 5-Trifluoromethylpyridone (2-Hydroxy-5-trifluoromethylpyridine) in Hydroponically Grown Plants

Application of NMR-based metabolomics to the investigation of salt stress in maize (Zea mays).

Application of biofluid 1 H nuclear magnetic resonance-based metabonomic techniques for the analysis of the biochemical effects of dietary isoflavones on human plasma profile

Application of chemometrics to 1H NMR spectroscopic data to investigate a relationship between human serum metabolic profiles and hypertension

Application of chemometrics to the 1H NMR spectra of apple juices: discrimination between apple varieties

Application of directly coupled LC–NMR–MS to the structural elucidation of metabolites of the HIV-1 reverse-transcriptase inhibitor BW935U83

Application of directly coupled high performance liquid chromatography-NMR-mass spectometry and 1H NMR spectroscopic studies to the investigation of 2,3-benzofuran metabolism in Sprague-Dawley rats

Application of inductively coupled plasma mass spectrometry and high-performance liquid chromatography—with parallel electrospray mass spectrometry to the investigation of the disposition and metabolic fate of 2-, 3- and 4-iodobenzoic acids in the

Application of novel solid phase extraction-NMR protocols for metabolic profiling of human urine

Application of orthogonal signal correction to minimise the effects of physical and biological variation in high resolution 1H NMR spectra of biofluids

Application of the FLIPSY pulse sequence for increased sensitivity in 1H NMR-based metabolic profiling studies

Application of the one-dimensional TOCSY pulse sequence in 750 MHz 1H-NMR spectroscopy for assignment of endogenous metabolite resonances in biofluids