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Lista de obras de Jane Visvader

1H, 15N and 13C assignments of FLIN4, an intramolecular LMO4:ldb1 complex

artículo científico publicado en 2002

A Phase Ib Dose-Escalation and Expansion Study of the BCL2 Inhibitor Venetoclax Combined with Tamoxifen in ER and BCL2-Positive Metastatic Breast Cancer

artículo científico publicado en 2018

A classic zinc finger from friend of GATA mediates an interaction with the coiled-coil of transforming acidic coiled-coil 3

scientific journal article

A critical epithelial survival axis regulated by MCL-1 maintains thymic function in mice

artículo científico publicado en 2017

A pooled shRNA screen for regulators of primary mammary stem and progenitor cells identifies roles for Asap1 and Prox1.

artículo científico publicado en 2015

A single-cell RNA expression atlas of normal, preneoplastic and tumorigenic states in the human breast

artículo científico publicado en 2021

Aberrant expression of LMO4 induces centrosome amplification and mitotic spindle abnormalities in breast cancer cells

artículo científico publicado el 1 de noviembre de 2010

Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers

artículo científico publicado en 2009

Abstract 1130: First-in-class KAT6A/KAT6B inhibitor CTx-648 (PF-9363) demonstrates potent anti-tumor activity in ER+ breast cancer with KAT6A dysregulation

artículo científico publicado en 2021

Aldehyde dehydrogenase activity is a biomarker of primitive normal human mammary luminal cells.

artículo científico publicado en 2012

BARD1 variants are not associated with breast cancer risk in Australian familial breast cancer

article

Barcoding reveals complex clonal behavior in patient-derived xenografts of metastatic triple negative breast cancer

artículo científico publicado en 2019

Breast cancer protein StarD10 identified by three-dimensional separation using free-flow electrophoresis, reversed-phase high-performance liquid chromatography, and sodium dodecyl sulfate-polyacrylamide gel electrophoresis

article

Breast cancer risk and the BRCA1 interacting protein CTIP

artículo científico publicado en 2007

CPAP is a novel stat5-interacting cofactor that augments stat5-mediated transcriptional activity

artículo científico publicado en 2002

Cancer stem cells in solid tumours: accumulating evidence and unresolved questions

artículo científico publicado en 2008

Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells

artículo científico publicado en 2006

Cancer stem cells: current status and evolving complexities

artículo científico

Canonical PRC2 function is essential for mammary gland development and affects chromatin compaction in mammary organoids

artículo científico publicado en 2018

Cell fate takes a slug in BRCA1-associated breast cancer

artículo científico publicado el 6 de abril de 2011

Cellular Mechanisms Underlying Intertumoral Heterogeneity

artículo científico publicado en 2015

Combined immune checkpoint blockade as a therapeutic strategy for BRCA1-mutated breast cancer

artículo científico publicado en 2017

Comparative oncogenomics identifies combinations of driver genes and drug targets in BRCA1-mutated breast cancer

artículo científico publicado en 2019

Construction of developmental lineage relationships in the mouse mammary gland by single-cell RNA profiling.

artículo científico publicado en 2017

Control of mammary stem cell function by steroid hormone signalling.

artículo científico publicado en 2010

Crystallization of FLINC4, an intramolecular LMO4-ldb1 complex

artículo científico publicado en 2003

Deaf-1 regulates epithelial cell proliferation and side-branching in the mammary gland

artículo científico publicado en 2008

Defective neural tube closure and anteroposterior patterning in mice lacking the LIM protein LMO4 or its interacting partner Deaf-1

scientific journal article

Derivation of a robust mouse mammary organoid system for studying tissue dynamics

artículo científico publicado en 2016

Differential hypermethylation of SOCS genes in ovarian and breast carcinomas.

artículo científico publicado en 2004

Differential methylation analysis of reduced representation bisulfite sequencing experiments using edgeR.

artículo científico publicado en 2017

Dimerization of CtIP, a BRCA1- and CtBP-interacting protein, is mediated by an N-terminal coiled-coil motif

artículo científico publicado en 2004

Discovery of novel mechanosensitive genes in vivo using mouse carotid artery endothelium exposed to disturbed flow

artículo científico publicado en 2010

Distinct nuclear receptor expression in stroma adjacent to breast tumors.

artículo científico publicado en 2013

Dual roles for Id4 in the regulation of estrogen signaling in the mammary gland and ovary.

artículo científico publicado en 2014

Dual targeting of CDK4/6 and BCL2 pathways augments tumor response in estrogen receptor positive breast cancer

artículo científico publicado en 2020

Dysregulation of histone methyltransferases in breast cancer - Opportunities for new targeted therapies?

artículo científico publicado en 2016

EGF-mediated induction of Mcl-1 at the switch to lactation is essential for alveolar cell survival

artículo científico publicado en 2015

Early asymmetry of gene transcription in embryonic human left and right cerebral cortex

artículo científico publicado en 2005

Elf5 is a principal cell lineage specific transcription factor in the kidney that contributes to Aqp2 and Avpr2 gene expression

artículo científico publicado en 2017

Elf5 is essential for early embryogenesis and mammary gland development during pregnancy and lactation

artículo científico publicado en 2005

Essential role for a novel population of binucleated mammary epithelial cells in lactation.

artículo científico publicado en 2016

Expression of S100A2 calcium-binding protein predicts response to pancreatectomy for pancreatic cancer

artículo científico publicado en 2009

FOXA1 is an essential determinant of ERalpha expression and mammary ductal morphogenesis

artículo científico publicado en 2010

Foxp1 Is Indispensable for Ductal Morphogenesis and Controls the Exit of Mammary Stem Cells from Quiescence

scientific article published on 25 October 2018

Frequency of the ATM IVS10-6T-->G variant in Australian multiple-case breast cancer families

artículo científico publicado en 2004

Frequent somatic mutations of GATA3 in non-BRCA1/BRCA2 familial breast tumors, but not in BRCA1-, BRCA2- or sporadic breast tumors

artículo científico publicado en 2009

Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation

artículo científico publicado en 2006

Gata-3 negatively regulates the tumor-initiating capacity of mammary luminal progenitor cells and targets the putative tumor suppressor caspase-14.

artículo científico publicado en 2011

Generation of a functional mammary gland from a single stem cell

artículo científico publicado en 2006

Global changes in the mammary epigenome are induced by hormonal cues and coordinated by Ezh2.

artículo científico publicado en 2013

Grhl3 and Lmo4 play coordinate roles in epidermal migration

artículo científico publicado en 2008

Halting triple negative breast cancer by targeting PROCR

scientific article published on 01 November 2019

High-resolution 3D imaging of fixed and cleared organoids

scientific article published on 03 May 2019

Identification of Taxreb107 as a lactogenic hormone responsive gene in mammary epithelial cells

artículo científico publicado en 2003

Identification of quiescent and spatially restricted mammary stem cells that are hormone responsive.

artículo científico publicado en 2017

Identification of the key LMO2-binding determinants on Ldb1.

artículo científico publicado en 2006

Impaired lactation in mice expressing dominant-negative FADD in mammary epithelium

artículo científico publicado en 2009

In situ identification of bipotent stem cells in the mammary gland.

artículo científico publicado en 2014

Increased serotonin-1A (5-HT1A) autoreceptor expression and reduced raphe serotonin levels in deformed epidermal autoregulatory factor-1 (Deaf-1) gene knock-out mice

artículo científico publicado en 2012

Insights into the cell of origin in breast cancer and breast cancer stem cells

artículo científico publicado en 2010

Integration of microRNA signatures of distinct mammary epithelial cell types with their gene expression and epigenetic portraits

artículo científico publicado en 2015

Intraclonal Plasticity in Mammary Tumors Revealed through Large-Scale Single-Cell Resolution 3D Imaging

scientific article published on 01 June 2019

Intraclonal Plasticity in Mammary Tumors Revealed through Large-Scale Single-Cell Resolution 3D Imaging

artículo científico publicado en 2019

Investigation of the transcriptional changes underlying functional defects in the mammary glands of prolactin receptor knockout mice

artículo científico publicado en 2003

Isolation and Propagation of Mammary Epithelial Stem and Progenitor Cells

scientific article published on 01 January 2019

Isolation of mouse mammary epithelial subpopulations: a comparison of leading methods

artículo científico

Jekyll or Hyde: does Matrigel provide a more or less physiological environment in mammary repopulating assays?

artículo científico publicado en 2011

Keeping abreast of the mammary epithelial hierarchy and breast tumorigenesis

artículo científico publicado en 2009

Knocking off SOCS genes in the mammary gland.

artículo científico publicado en 2007

LIM-domain-binding protein 1: a multifunctional cofactor that interacts with diverse proteins.

artículo científico publicado en 2003

LMO4 expression in squamous cell carcinoma of the anterior tongue.

artículo científico publicado en 2011

Letter to the Editor: (1)H, (15)N and (13)C assignments of FLIN4, an intramolecular LMO4:ldb1 complex

Lgr5+ pericentral hepatocytes are self-maintained in normal liver regeneration and susceptible to hepatocarcinogenesis

artículo científico publicado en 2019

Lineage Tracing of Mammary Stem and Progenitor Cells

artículo científico publicado en 2017

Lineage enforcement by inductive mesenchyme on adult epithelial stem cells across developmental germ layers

artículo científico publicado en 2009

Lineage specific methylation of the Elf5 promoter in mammary epithelial cells.

artículo científico publicado en 2011

Long-term culture, genetic manipulation and xenotransplantation of human normal and breast cancer organoids

scientific article published on 10 March 2021

Loss of STARD10 expression identifies a group of poor prognosis breast cancers independent of HER2/Neu and triple negative status.

artículo científico publicado en 2010

Loss of the LIM domain protein Lmo4 in the mammary gland during pregnancy impedes lobuloalveolar development

artículo científico publicado en 2005

Mammary stem cells and mammopoiesis

artículo científico publicado en 2006

Mammary stem cells and their regulation by steroid hormones

scientific article published on 01 May 2011

Modeling breast cancer using CRISPR/Cas9-mediated engineering of human breast organoids

artículo científico publicado en 2019

Murine Mammary Epithelial Stem Cells: Discovery, Function, and Current Status

artículo científico publicado el 1 de febrero de 2011

Mutation analysis of FANCD2, BRIP1/BACH1, LMO4 and SFN in familial breast cancer

artículo científico publicado en 2005

Mutational analysis of the LMO4 gene, encoding a BRCA1-interacting protein, in breast carcinomas

artículo científico publicado en 2003

New Monoclonal Antibodies to Defined Cell Surface Proteins on Human Pluripotent Stem Cells

artículo científico publicado en 2016

Notch signaling regulates mammary stem cell function and luminal cell-fate commitment.

artículo científico publicado en 2008

Out-RANKing BRCA1 in Mutation Carriers.

artículo científico publicado en 2017

Overexpression of LMO4 induces mammary hyperplasia, promotes cell invasion, and is a predictor of poor outcome in breast cancer

artículo científico publicado en 2005

Patient-derived xenograft (PDX) models in basic and translational breast cancer research.

artículo científico publicado en 2016

Patient-derived xenograft models of breast cancer and their predictive power

artículo científico publicado en 2015

Persistent Activation of NF-κB in BRCA1-Deficient Mammary Progenitors Drives Aberrant Proliferation and Accumulation of DNA Damage.

artículo científico publicado en 2016

Preclinical small molecule WEHI-7326 overcomes drug resistance and elicits response in patient-derived xenograft models of human treatment-refractory tumors

artículo científico publicado en 2021

Proteomic profiling of secretome and adherent plasma membranes from distinct mammary epithelial cell subpopulations.

artículo científico publicado en 2011

Publisher Correction: Barcoding reveals complex clonal behavior in patient-derived xenografts of metastatic triple negative breast cancer

artículo científico publicado en 2019

R code and downstream analysis objects for the scRNA-seq atlas of normal and tumorigenic human breast tissue

publication published on 23 March 2022

RANK ligand as a potential target for breast cancer prevention in BRCA1-mutation carriers.

artículo científico publicado en 2016

RE: Bilateral Oophorectomy and Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

artículo científico publicado en 2017

ROAST: rotation gene set tests for complex microarray experiments

artículo científico publicado en 2010

RUNX2 Mediates Plasmacytoid Dendritic Cell Egress from the Bone Marrow and Controls Viral Immunity.

artículo científico publicado en 2016

Recruitment and activation of SLK at the leading edge of migrating cells requires Src family kinase activity and the LIM-only protein 4

scientific journal article

Remodeling of the lymphatic vasculature during mouse mammary gland morphogenesis is mediated via epithelial-derived lymphangiogenic stimuli

artículo científico publicado en 2012

Replication of in vitro constructed viroid mutants: location of the pathogenicity-modulating domain of citrus exocortis viroid.

artículo científico publicado en 1986

Resident macrophages influence stem cell activity in the mammary gland

artículo científico publicado en 2009

Runx2 is a novel regulator of mammary epithelial cell fate in development and breast cancer

artículo científico publicado en 2014

Scribble modulates the MAPK/Fra1 pathway to disrupt luminal and ductal integrity and suppress tumour formation in the mammary gland

artículo científico publicado en 2014

Sensitization of BCL-2-expressing breast tumors to chemotherapy by the BH3 mimetic ABT-737

artículo científico publicado en 2011

Shedding light on mammary stem cells and tumorigenesis

artículo científico publicado en 2006

Single cell transcriptome atlas of mouse mammary epithelial cells across development

artículo científico publicado en 2021

Socs2 and elf5 mediate prolactin-induced mammary gland development

scientific journal article

StarD10, a START domain protein overexpressed in breast cancer, functions as a phospholipid transfer protein.

artículo científico publicado en 2005

Stem Cells and the Differentiation Hierarchy in Mammary Gland Development

scientific article published on 20 September 2019

Stem cells and cancer - the promise and puzzles

artículo científico publicado en 2010

Steroid hormone receptor status of mouse mammary stem cells

artículo científico publicado en 2006

Structural basis for the recognition of ldb1 by the N-terminal LIM domains of LMO2 and LMO4

artículo científico publicado en 2003

Synergistic action of the MCL-1 inhibitor S63845 with current therapies in preclinical models of triple-negative and HER2-amplified breast cancer

artículo científico publicado en 2017

Tandem LIM domains provide synergistic binding in the LMO4:Ldb1 complex

artículo científico publicado en 2004

Targeting BCL-2 with the BH3 mimetic ABT-199 in estrogen receptor-positive breast cancer

artículo científico publicado en 2013

Targeting triple-negative breast cancers with the Smac-mimetic birinapant

artículo científico publicado en 2020

The Ets transcription factor Elf5 specifies mammary alveolar cell fate

artículo científico publicado en 2008

The LIM domain protein LMO4 interacts with the cofactor CtIP and the tumor suppressor BRCA1 and inhibits BRCA1 activity

artículo científico publicado en 2002

The LIM domain protein Lmo4 is highly expressed in proliferating mouse epithelial tissues

artículo científico publicado en 2005

The complexities and caveats of lineage tracing in the mammary gland.

artículo científico publicado en 2016

The emerging picture of the mouse mammary stem cell

artículo científico publicado en 2007

The future of mammary stem cell biology: the power of in vivo transplants

artículo científico publicado en 2008

The mammary progenitor marker CD61/beta3 integrin identifies cancer stem cells in mouse models of mammary tumorigenesis

scientific article published on 01 October 2008

The mammary stem cell hierarchy.

artículo científico publicado en 2014

The molecular culprits underlying precocious mammary gland involution

artículo científico publicado en 2007

The phosphoprotein StarD10 is overexpressed in breast cancer and cooperates with ErbB receptors in cellular transformation

artículo científico publicado en 2004

The unmasking of novel unipotent stem cells in the mammary gland

artículo científico publicado en 2011

Threonine 391 phosphorylation of the human prolactin receptor mediates a novel interaction with 14-3-3 proteins

artículo científico publicado en 2003

Tissue-resident ductal macrophages survey the mammary epithelium and facilitate tissue remodelling

artículo científico publicado en 2020

Tissue-specific designs of stem cell hierarchies

artículo científico publicado en 2016

Transcription factor Lmo4 defines the shape of functional areas in developing cortices and regulates sensorimotor control

scientific article published on 16 December 2008

Transcriptional regulators in mammary gland development and cancer

artículo científico publicado en 2003

Transcriptome analyses of mouse and human mammary cell subpopulations reveal multiple conserved genes and pathways

artículo científico publicado en 2010

Two promoters within the human LMO4 gene contribute to its overexpression in breast cancer cells

artículo científico publicado en 2003

c-myc as a mediator of accelerated apoptosis and involution in mammary glands lacking Socs3.

artículo científico publicado en 2006