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Lista de obras de Hiroshi Hamada

A GPI processing phospholipase A2, PGAP6, modulates Nodal signaling in embryos by shedding CRIPTO.

artículo científico publicado en 2016

A Wnt5 Activity Asymmetry and Intercellular Signaling via PCP Proteins Polarize Node Cells for Left-Right Symmetry Breaking.

artículo científico publicado en 2017

Absence of Radial Spokes in Mouse Node Cilia Is Required for Rotational Movement but Confers Ultrastructural Instability as a Trade-Off.

artículo científico publicado en 2015

An Nkx2-5/Bmp2/Smad1 negative feedback loop controls heart progenitor specification and proliferation

artículo científico publicado en 2007

Antagonism between Smad1 and Smad2 signaling determines the site of distal visceral endoderm formation in the mouse embryo.

scientific article published on 19 January 2009

Asymmetric rotational stroke in mouse node cilia during left-right determination

artículo científico publicado en 2013

Baf60c is a nuclear Notch signaling component required for the establishment of left-right asymmetry

artículo científico publicado en 2007

Both Nodal signalling and stochasticity select for prospective distal visceral endoderm in mouse embryos

artículo científico publicado en 2017

Breakthroughs and future challenges in left-right patterning

artículo científico publicado en 2008

CFAP45 deficiency causes situs abnormalities and asthenospermia by disrupting an axonemal adenine nucleotide homeostasis module

scientific article published on 02 November 2020

CFAP53 regulates mammalian cilia-type motility patterns through differential localization and recruitment of axonemal dynein components

artículo científico publicado en 2020

CYP26A1 and CYP26C1 cooperate in degrading retinoic acid within the equatorial retina during later eye development

scientific journal article

Cell fate decisions and axis determination in the early mouse embryo.

artículo científico publicado en 2012

Changes in bacterial community structure in a full-scale membrane bioreactor for municipal wastewater treatment

artículo científico publicado en 2016

Characterization of Pitx2c expression in the mouse heart using a reporter transgene.

artículo científico publicado en 2011

Cilia at the node of mouse embryos sense fluid flow for left-right determination via Pkd2

artículo científico publicado en 2012

Cilia in Left-Right Symmetry Breaking

artículo científico publicado en 2017

Ciliogenesis-coupled accumulation of IFT-B proteins in a novel cytoplasmic compartment

artículo científico publicado en 2019

Cloning of inv, a gene that controls left/right asymmetry and kidney development.

artículo científico publicado en 1998

Cluap1 localizes preferentially to the base and tip of cilia and is required for ciliogenesis in the mouse embryo

scientific journal article

Comparison of gene expression in male and female mouse blastocysts revealed imprinting of the X-linked gene, Rhox5/Pem, at preimplantation stages.

artículo científico publicado en 2006

Conserved regulation and role of Pitx2 in situs-specific morphogenesis of visceral organs

artículo científico publicado en 2006

Coordinated ciliary beating requires Odf2-mediated polarization of basal bodies via basal feet

artículo científico publicado en 2012

De novo formation of left-right asymmetry by posterior tilt of nodal cilia

artículo científico publicado en 2005

Deletion of the Dishevelled family of genes disrupts anterior-posterior axis specification and selectively prevents mesoderm differentiation

artículo científico publicado en 2020

Determination of left–right patterning of the mouse embryo by artificial nodal flow

scientific article published in Nature

Diversity of left-right symmetry breaking strategy in animals

artículo científico publicado en 2020

Dysregulation of the PDGFRA gene causes inflow tract anomalies including TAPVR: integrating evidence from human genetics and model organisms

artículo científico publicado en 2010

EpCAM contributes to formation of functional tight junction in the intestinal epithelium by recruiting claudin proteins

artículo científico publicado en 2012

Establishment of vertebrate left-right asymmetry

artículo científico publicado en 2002

Fluid flow and interlinked feedback loops establish left-right asymmetric decay of Cerl2 mRNA.

artículo científico publicado en 2012

Fluid flow-induced left-right asymmetric decay of Dand5 mRNA in the mouse embryo requires a Bicc1-Ccr4 RNA degradation complex

artículo científico publicado en 2021

Generation of robust left-right asymmetry in the mouse embryo requires a self-enhancement and lateral-inhibition system.

artículo científico publicado en 2006

Genetic Analysis Reveals a Hierarchy of Interactions between Polycystin-Encoding Genes and Genes Controlling Cilia Function during Left-Right Determination

artículo científico publicado en 2016

Haemodynamics determined by a genetic programme govern asymmetric development of the aortic arch.

artículo científico publicado en 2007

Hyaluronan Works on the Right for Directional Gut Looping

artículo científico publicado en 2018

Hydrodynamic phase locking in mouse node cilia

artículo científico publicado en 2013

Identification of a novel left-right asymmetrically expressed gene in the mouse belonging to the BPI/PLUNC superfamily.

artículo científico publicado en 2004

In search of Turing in vivo: understanding Nodal and Lefty behavior.

artículo científico publicado en 2012

Increased retinoic acid levels through ablation of Cyp26b1 determine the processes of embryonic skin barrier formation and peridermal development

scientific journal article

Inhibition of Nodal signalling by Lefty mediated through interaction with common receptors and efficient diffusion

artículo científico publicado en 2002

Interplay of SOX and POU factors in regulation of the Nestin gene in neural primordial cells

scientific journal article

Left-right asymmetric expression of the TGF beta-family member lefty in mouse embryos

artículo científico publicado en 1996

Left-right asymmetry in the level of active Nodal protein produced in the node is translated into left-right asymmetry in the lateral plate of mouse embryos.

artículo científico publicado en 2011

Left-right patterning of the mouse lateral plate requires nodal produced in the node

scientific journal article

Left-right patterning: conserved and divergent mechanisms

artículo científico publicado en 2012

Localization of Inv in a distinctive intraciliary compartment requires the C-terminal ninein-homolog-containing region.

artículo científico publicado en 2008

Long-range action of Nodal requires interaction with GDF1.

artículo científico publicado en 2007

Loss of Cited2 causes congenital heart disease by perturbing left-right patterning of the body axis

artículo científico publicado en 2010

Loss of Fam60a, a Sin3a subunit, results in embryonic lethality and is associated with aberrant methylation at a subset of gene promoters

article

Loss of PYCR2 Causes Neurodegeneration by Increasing Cerebral Glycine Levels via SHMT2

artículo científico publicado en 2020

Making the Right Loop for the heart

artículo científico publicado en 2020

Mechanisms of left-right asymmetry and patterning: driver, mediator and responder

artículo científico publicado en 2014

Meteorin: a secreted protein that regulates glial cell differentiation and promotes axonal extension

scientific journal article

Molecular and cellular basis of left-right asymmetry in vertebrates

artículo científico publicado en 2020

Nodal antagonists in the anterior visceral endoderm prevent the formation of multiple primitive streaks

artículo científico publicado en 2002

Nodal antagonists regulate formation of the anteroposterior axis of the mouse embryo

scientific journal article

Nodal paralogues underlie distinct mechanisms for visceral left-right asymmetry in reptiles and mammals

artículo científico publicado en 2020

Nodal signaling induces the midline barrier by activating Nodal expression in the lateral plate

scientific journal article

Nodal/activin signaling promotes male germ cell fate and suppresses female programming in somatic cells

artículo científico publicado en 2012

Notch signaling regulates left-right asymmetry determination by inducing Nodal expression

scientific journal article

Origin and role of distal visceral endoderm, a group of cells that determines anterior-posterior polarity of the mouse embryo.

artículo científico publicado en 2011

Origin of body axes in the mouse embryo

artículo científico publicado en 2007

Origin of cellular asymmetries in the pre-implantation mouse embryo: a hypothesis.

artículo científico publicado en 2014

Overall Architecture of the Intraflagellar Transport (IFT)-B Complex Containing Cluap1/IFT38 as an Essential Component of the IFT-B Peripheral Subcomplex

artículo científico publicado en 2016

Pih1d3 is required for cytoplasmic preassembly of axonemal dynein in mouse sperm

artículo científico publicado en 2014

Planar polarization of node cells determines the rotational axis of node cilia.

artículo científico publicado en 2010

Pleiotropic and isoform-specific functions for Pitx2 in superior colliculus and hypothalamic neuronal development

artículo científico publicado en 2012

Rab7-Mediated Endocytosis Establishes Patterning of Wnt Activity through Inactivation of Dkk Antagonism

artículo científico publicado en 2020

Regulation of retinoic acid distribution is required for proximodistal patterning and outgrowth of the developing mouse limb

scientific journal article

Removal of maternal retinoic acid by embryonic CYP26 is required for correct Nodal expression during early embryonic patterning

artículo científico publicado en 2009

Retinoic acid signaling regulates sonic hedgehog and bone morphogenetic protein signalings during genital tubercle development.

artículo científico publicado en 2011

Retinoid signaling determines germ cell fate in mice

scientific journal article

Reversal of left-right asymmetry induced by aberrant Nodal signaling in the node of mouse embryos.

artículo científico publicado en 2009

Role of Ca2+ transients at the node of the mouse embryo in breaking of left-right symmetry

artículo científico publicado en 2020

Role of physical forces in embryonic development.

artículo científico

Roles of Motile and Immotile Cilia in Left-Right Symmetry Breaking

Roles of cilia, fluid flow, and Ca2+ signaling in breaking of left-right symmetry.

artículo científico

Rsph4a is essential for the triplet radial spoke head assembly of the mouse motile cilia

artículo científico publicado en 2020

SHH propagates distal limb bud development by enhancing CYP26B1-mediated retinoic acid clearance via AER-FGF signalling

artículo científico publicado en 2011

Self-regulated left-right asymmetric expression of Pitx2c in the developing mouse limb

artículo científico publicado en 2014

Shape meets polarity in Japan.

artículo científico publicado en 2009

Simulation of the nodal flow of mutant embryos with a small number of cilia: comparison of mechanosensing and vesicle transport hypotheses

article

Single-Cell Expression Profiling Reveals a Dynamic State of Cardiac Precursor Cells in the Early Mouse Embryo

artículo científico publicado en 2015

Single-oocyte transcriptome analysis reveals aging-associated effects influenced by life stage and calorie restriction

artículo científico publicado en 2021

Situs inversus and ciliary abnormalities: 20 years later, what is the connection?

artículo científico publicado en 2015

Spatial restriction of bone morphogenetic protein signaling in mouse gastrula through the mVam2-dependent endocytic pathway

artículo científico publicado en 2012

Sulfated glycosaminoglycans are necessary for Nodal signal transmission from the node to the left lateral plate in the mouse embryo.

artículo científico publicado en 2007

TGFβ signaling in establishing left-right asymmetry

artículo científico

TTC25 Deficiency Results in Defects of the Outer Dynein Arm Docking Machinery and Primary Ciliary Dyskinesia with Left-Right Body Asymmetry Randomization

artículo científico publicado en 2016

Tbx6 controls left-right asymmetry through regulation of Gdf1.

artículo científico publicado en 2018

The Motion of An Inv Nodal Cilium: a Realistic Model Revealing Dynein-Driven Ciliary Motion with Microtubule Mislocalization

scientific article published on 14 December 2018

The dynamic right-to-left translocation of Cerl2 is involved in the regulation and termination of Nodal activity in the mouse node.

artículo científico publicado en 2013

The dynein-triggered ciliary motion in embryonic nodes: an exploratory study based on computational models

artículo científico publicado en 2014

The left-right axis in the mouse: from origin to morphology

artículo científico publicado en 2006

The left-right determinant Inversin is a component of node monocilia and other 9+0 cilia.

artículo científico publicado en 2003

The mouse embryo autonomously acquires anterior-posterior polarity at implantation

artículo científico publicado en 2006

Translation of anterior-posterior polarity into left-right polarity in the mouse embryo.

artículo científico publicado en 2010

Transport of the outer dynein arm complex to cilia requires a cytoplasmic protein Lrrc6.

artículo científico publicado en 2016

Two nodal-responsive enhancers control left-right asymmetric expression of Nodal.

artículo científico publicado en 2005

Two rotating cilia in the node cavity are sufficient to break left-right symmetry in the mouse embryo.

artículo científico publicado en 2012

Ways, means and consequences of shaping morphogen gradients

artículo científico publicado en 2013

Wnt signalling escapes to cilia

scientific article published on 01 June 2011

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