Lista de obras - Detlef Schuppan - Dominio Público Uruguay

3D analysis of microvasculature in murine liver fibrosis models using synchrotron radiation-based microtomography

artículo científico publicado en 2020

A change of peginterferon may permit continuation of antiviral therapy in hepatitis C virus-infected patients with interstitial pneumonitis

artículo científico publicado en 2010

A key role of GARP in the immune suppressive tumor microenvironment

artículo científico publicado en 2016

A quadruple therapy synergistically blocks proliferation and promotes apoptosis of hepatoma cells.

artículo científico publicado en 2004

A randomized, placebo-controlled trial of emricasan in patients with NASH and F1-F3 fibrosis

artículo científico publicado en 2019

A simple validated gluten-free diet adherence survey for adults with celiac disease

artículo científico publicado en 2009

A validated disease-specific symptom index for adults with celiac disease

scientific article published on 07 August 2009

AMPK regulates macrophage polarization in adipose tissue inflammation and NASH ⬇️

artículo científico publicado el 6 de octubre de 2012

Activation and dramatically increased cytolytic activity of tumor specific T lymphocytes after radio-frequency ablation in patients with hepatocellular carcinoma and colorectal liver metastases

artículo científico publicado en 2006

Activation of tumor-specific T lymphocytes by radio-frequency ablation of the VX2 hepatoma in rabbits ⬇️

artículo científico publicado el 1 de octubre de 2003

Acupuncture and Moxibustion in the Treatment of Active Crohn’s Disease: A Randomized Controlled Study

artículo científico publicado en 2004

Additive antitumour response to the rabbit VX2 hepatoma by combined radio frequency ablation and toll like receptor 9 stimulation

artículo científico publicado en 2014

Adenosine: tipping the balance towards hepatic steatosis and fibrosis

artículo científico publicado en 2010

Alcohol dehydrogenase 1C*1 allele is a genetic marker for alcohol-associated cancer in heavy drinkers

artículo científico publicado en 2006

Anti-fibrotic therapy: lost in translation?

artículo científico

Anti-tumor necrosis factor-alpha monoclonal antibody therapy in severe alcoholic hepatitis.

artículo científico publicado en 2003

Assessment of liver fibrosis progression and regression by a serological collagen turnover profile

scientific article published on 30 August 2018

Association of myeloperoxidase promotor polymorphism with cirrhosis in patients with hereditary hemochromatosis

artículo científico publicado en 2005

Blockade of IGF-1 receptor tyrosine kinase has antineoplastic effects in hepatocellular carcinoma cells

artículo científico publicado en 2006

Broad-spectrum matrix metalloproteinase inhibition curbs inflammation and liver injury but aggravates experimental liver fibrosis in mice

artículo científico publicado en 2010

CD8+ T cells drive adipose tissue inflammation--a novel clue for NASH pathogenesis?

artículo científico publicado en 2009

CFTR dysfunction predisposes to fibrotic liver disease in a murine model ⬇️

artículo científico publicado el 7 de junio de 2012

Cancer-associated circulating large extracellular vesicles in cholangiocarcinoma and hepatocellular carcinoma.

artículo científico publicado en 2017

Celiac disease: from pathogenesis to novel therapies

artículo científico publicado en 2009

Changes in hepatic perfusion after administration of hydroxyethyl starch in intensive care patients assessed using color-coded Doppler sonography

artículo científico publicado en 2002

Circulating microparticles as disease-specific biomarkers of severity of inflammation in patients with hepatitis C or nonalcoholic steatohepatitis.

artículo científico publicado en 2012

Cirrhosis risk score of the donor organ predicts early fibrosis progression after liver transplantation

artículo científico publicado en 2019

Combined endostatin/sFlt-1 antiangiogenic gene therapy is highly effective in a rat model of HCC.

artículo científico publicado en 2005

Comparison of Gene Expression Patterns Between Mouse Models of Nonalcoholic Fatty Liver Disease and Liver Tissues From Patients

artículo científico publicado en 2016

Comparison of murine steatohepatitis models identifies a dietary intervention with robust fibrosis, ductular reaction, and rapid progression to cirrhosis and cancer

scientific article published on 21 October 2019

Comparison of transient elastography, serum markers and clinical signs for the diagnosis of compensated cirrhosis

artículo científico publicado en 2010

Deletion of organic cation transporter Oct3 promotes hepatic fibrosis via upregulation of TGFβ

scientific article published on 26 June 2019

Dendritic cells in liver injury and fibrosis: Shortcomings and promises ⬇️

artículo científico publicado el 29 de mayo de 2013

Despite sequence homologies to gluten, salivary proline-rich proteins do not elicit immune responses central to the pathogenesis of celiac disease

artículo científico publicado en 2015

Dextran-based therapeutic nanoparticles for hepatic drug delivery.

artículo científico publicado en 2016

Dietary wheat amylase trypsin inhibitors promote features of murine non-alcoholic fatty liver disease

scientific article published on 25 November 2019

Disordered pancreatic inflammatory responses and inhibition of fibrosis in CD39-null mice

artículo científico publicado en 2007

Early changes in dynamic biomarkers of liver fibrosis in hepatitis C virus-infected patients treated with sofosbuvir

artículo científico publicado en 2015

Elevated transaminases as a predictor of coma in a patient with anorexia nervosa: a case report and review of the literature

artículo científico publicado en 2010

Endostatin competes with bFGF for binding to heparin-like glycosaminoglycans

artículo científico publicado en 2005

Endothelin-1 enhances fibrogenic gene expression, but does not promote DNA synthesis or apoptosis in hepatic stellate cells

artículo científico publicado en 2006

Enhanced liver fibrosis test for the non-invasive diagnosis of fibrosis in patients with NAFLD: A systematic review and meta-analysis

scientific article published on 07 April 2020

Enhanced protection of C57 BL/6 vs Balb/c mice to melanoma liver metastasis is mediated by NK cells.

artículo científico publicado en 2017

Epithelial-to-mesenchymal transition in liver fibrosis: dead or alive?

scientific article published on 01 August 2010

Etiologies and predictors of diagnosis in nonresponsive celiac disease

artículo científico publicado en 2007

Extrahepatic platelet-derived growth factor-β, delivered by platelets, promotes activation of hepatic stellate cells and biliary fibrosis in mice

artículo científico publicado en 2014

Factors that influence adherence to a gluten-free diet in adults with celiac disease

artículo científico publicado en 2008

Failure of Fibrotic Liver Regeneration in Mice Is Linked to a Severe Fibrogenic Response Driven by Hepatic Progenitor Cell Activation ⬇️

artículo científico publicado el 14 de mayo de 2013

Fibroblast growth factor 21 limits lipotoxicity by promoting hepatic fatty acid activation in mice on methionine and choline-deficient diets

artículo científico publicado en 2014

Fibrosis evaluation by transient elastography in alcoholic liver disease: Is the histological scoring system impacting cutoff values?

artículo científico publicado en 2017

Gliptins Suppress Inflammatory Macrophage Activation to Mitigate Inflammation, Fibrosis, Oxidative Stress, and Vascular Dysfunction in Models of Nonalcoholic Steatohepatitis and Liver Fibrosis

artículo científico publicado en 2017

Growth factor receptors and related signalling pathways as targets for novel treatment strategies of hepatocellular cancer

artículo científico publicado en 2008

Gut-CNS-Axis as Possibility to Modulate Inflammatory Disease Activity-Implications for Multiple Sclerosis

artículo científico publicado en 2017

HIV and HCV cooperatively promote hepatic fibrogenesis via induction of reactive oxygen species and NFkappaB

artículo científico publicado en 2010

Halofuginone induces matrix metalloproteinases in rat hepatic stellate cells via activation of p38 and NFkappaB.

artículo científico publicado en 2006

Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans

artículo científico publicado en 2008

Helicobacter pylori upregulates prion protein expression in gastric mucosa: a possible link to prion disease.

artículo científico publicado en 2005

Hepatic B cell leukemia-3 promotes hepatic steatosis and inflammation through insulin-sensitive metabolic transcription factors

artículo científico publicado en 2016

Hepatic fibrosis: Concept to treatment

artículo científico

Hepatic fibrosis: from bench to bedside

artículo científico publicado en 2002

Hepatitis C virus-replicating hepatocytes induce fibrogenic activation of hepatic stellate cells.

artículo científico publicado en 2005

Hepatitis C virus-specific T-cell-derived transforming growth factor beta is associated with slow hepatic fibrogenesis

artículo científico publicado en 2012

Hepatitis induced by Kava (Piper methysticum rhizoma)

scientific article published on 01 July 2003

Hepatocellular carcinoma in nonalcoholic fatty liver disease: A link between oxidative stress and T-cell suppression

artículo científico publicado en 2016

Hepatocellular carcinomas do not compromise quantitative tests of liver function

artículo científico publicado en 2005

Hepatocyte growth factor and c-Met expression in rat and human liver fibrosis.

artículo científico publicado en 2004

Hepatocyte transplantation activates hepatic stellate cells with beneficial modulation of cell engraftment in the rat.

artículo científico publicado en 2005

Hepatotoxicity of alcohol-induced polar retinol metabolites involves apoptosis via loss of mitochondrial membrane potential.

artículo científico publicado en 2005

Herbal hepatotoxicity

artículo científico publicado en 2005

Histone deacetylase inhibitor MS-275 alone or combined with bortezomib or sorafenib exhibits strong antiproliferative action in human cholangiocarcinoma cells

artículo científico publicado en 2007

Human T cell microparticles circulate in blood of hepatitis patients and induce fibrolytic activation of hepatic stellate cells.

artículo científico publicado en 2010

Human risk allele HLA-DRB1*0405 predisposes class II transgenic Ab0 NOD mice to autoimmune pancreatitis

artículo científico publicado en 2010

Hydroxyproline-containing collagen analogs trigger the release and activation of collagen-sequestered proMMP-2 by competition with prodomain-derived peptide P33-42.

artículo científico publicado en 2011

Hypoxia-inducible factor 1 alpha under rapid enzymatic hypoxia: cells sense decrements of oxygen but not hypoxia per se.

artículo científico publicado en 2008

IL-4 Receptor Alpha Signaling through Macrophages Differentially Regulates Liver Fibrosis Progression and Reversal.

artículo científico publicado en 2018

IL28B genotype is associated with differential expression of intrahepatic interferon-stimulated genes in patients with chronic hepatitis C.

artículo científico publicado en 2010

In Vivo Gene-Silencing in Fibrotic Liver by siRNA-Loaded Cationic Nanohydrogel Particles

artículo científico publicado en 2015

In Vivo siRNA Delivery to Immunosuppressive Liver Macrophages by α-Mannosyl-Functionalized Cationic Nanohydrogel Particles

artículo científico publicado en 2020

In vitro differentiation of human monocytes into dendritic cells by peptic-tryptic digest of gliadin is independent of genetic predisposition and the presence of celiac disease.

artículo científico publicado en 2008

Increased hepatic fibrosis and JNK2-dependent liver injury in mice exhibiting hepatocyte-specific deletion of cFLIP

scientific article published on 14 June 2012

Increased plasma levels of microparticles expressing CD39 and CD133 in acute liver injury.

artículo científico publicado en 2013

Inducible knockdown of procollagen I protects mice from liver fibrosis and leads to dysregulated matrix genes and attenuated inflammation

artículo científico publicado en 2017

Inhibition of integrin alphavbeta6 on cholangiocytes blocks transforming growth factor-beta activation and retards biliary fibrosis progression

artículo científico publicado en 2008

Innate immunity and coeliac disease

scientific article published on 01 July 2003

Integrin alphavbeta6 is a marker of the progression of biliary and portal liver fibrosis and a novel target for antifibrotic therapies

artículo científico publicado en 2008

Integrin αvβ6 critically regulates hepatic progenitor cell function and promotes ductular reaction, fibrosis, and tumorigenesis.

scientific article published on 08 October 2015

Integrin-mediated control of cell growth

artículo científico publicado en 2003

Interstitial collagens I, III, and VI sequester and modulate the multifunctional cytokine oncostatin M.

artículo científico publicado en 2001

Iron, HCV, and liver cancer: hard metal setting the pace?

artículo científico publicado en 2006

Keratin variants associate with progression of fibrosis during chronic hepatitis C infection

artículo científico publicado en 2006

Kinetics of the histological, serological and symptomatic responses to gluten challenge in adults with coeliac disease ⬇️

artículo científico publicado el 22 de mayo de 2012

Liver cirrhosis

artículo científico publicado en 2008

Liver fibrosis: Direct antifibrotic agents and targeted therapies

artículo científico publicado en 2018

Liver-homing of purified glucose oxidase: a novel in vivo model of physiological hepatic oxidative stress (H2O2)

artículo científico publicado en 2006

Loss of organic cation transporter 3 (Oct3) leads to enhanced proliferation and hepatocarcinogenesis.

artículo científico publicado en 2017

Lysyl oxidase (LOX) family members: rationale and their potential as therapeutic targets for liver fibrosis

artículo científico publicado en 2020

Lysyl oxidase activity contributes to collagen stabilization during liver fibrosis progression and limits spontaneous fibrosis reversal in mice.

artículo científico publicado en 2015

Macrophage recruitment by fibrocystin-defective biliary epithelial cells promotes portal fibrosis in congenital hepatic fibrosis.

artículo científico

Macrophage-mediated phagocytosis of apoptotic cholangiocytes contributes to reversal of experimental biliary fibrosis.

artículo científico publicado en 2010

Mass-encoded synthetic biomarkers for multiplexed urinary monitoring of disease

artículo científico publicado en 2012

Mdr2 (Abcb4)-/- mice spontaneously develop severe biliary fibrosis via massive dysregulation of pro- and antifibrogenic genes

artículo científico publicado en 2005

Microparticles: Modulators and biomarkers of liver disease

artículo científico publicado en 2012

Monitoring Translation Activity of mRNA-Loaded Nanoparticles in Mice

artículo científico publicado en 2018

Mouse models of nonalcoholic steatohepatitis Towards optimization of their relevance to human NASH

artículo científico publicado en 2019

Myeloid cells as orchestrators of the tumor microenvironment: novel targets for nanoparticular cancer therapy

artículo científico publicado en 2016

Nano-Enhanced Cancer Immunotherapy: Immunology Encounters Nanotechnology

scientific article published on 15 September 2020

Nanoparticles and the immune system: challenges and opportunities

artículo científico publicado en 2016

No role of matrixmetalloproteinase-3 genetic promoter polymorphism 1171 as a risk factor for cirrhosis in alcoholic liver disease

artículo científico publicado en 2008

Non-Celiac Gluten sensitivity: the new frontier of gluten related disorders

artículo científico publicado en 2013

Non-alcoholic steatohepatitis: pathogenesis and novel therapeutic approaches.

artículo científico

Non-celiac wheat sensitivity: differential diagnosis, triggers and implications

artículo científico publicado en 2015

Nonalcoholic steatohepatitis: the therapeutic challenge of a global epidemic

artículo científico publicado en 2011

Novel Opportunities for Cathepsin S Inhibitors in Cancer Immunotherapy by Nanocarrier-Mediated Delivery

artículo científico publicado en 2020

Novel engineered targeted interferon-gamma blocks hepatic fibrogenesis in mice

artículo científico publicado en 2011

Nutritional Wheat Amylase-Trypsin Inhibitors Promote Intestinal Inflammation via Activation of Myeloid Cells

artículo científico publicado en 2016

Open conformation tissue transglutaminase testing for celiac dietary assessment ⬇️

artículo científico publicado el 18 de enero de 2012

Optimized Mouse Models for Liver Fibrosis

artículo científico publicado en 2017

Past, present and future of immunology in Mainz

artículo científico publicado en 2016

Pathomechanisms in Celiac Disease ⬇️

artículo científico publicado el 1 de octubre de 2003

Peripheral benzodiazepine receptor ligands induce apoptosis and cell cycle arrest in human hepatocellular carcinoma cells and enhance chemosensitivity to paclitaxel, docetaxel, doxorubicin and the Bcl-2 inhibitor HA14-1.

artículo científico publicado en 2004

Pharmacological inhibition of integrin alphavbeta3 aggravates experimental liver fibrosis and suppresses hepatic angiogenesis

artículo científico publicado en 2009

Pharmacological inhibition of the vitronectin receptor abrogates PDGF-BB-induced hepatic stellate cell migration and activation in vitro

artículo científico publicado en 2006

Phosphate Groups in the Lipid A Moiety Determine the Effects of LPS on Hepatic Stellate Cells: A Role for LPS-Dephosphorylating Activity in Liver Fibrosis

artículo científico publicado en 2020

Physicochemical and Preclinical Evaluation of Spermine-Derived Surfactant Liposomes for in Vitro and in Vivo siRNA-Delivery to Liver Macrophages

artículo científico publicado en 2016

Pitavastatin enhances antiviral efficacy of standard pegylated interferon plus ribavirin in patients with chronic hepatitis C: A prospective randomized pilot study ⬇️

artículo científico publicado el 28 de junio de 2011

Podoplanin discriminates distinct stromal cell populations and a novel progenitor subset in the liver

artículo científico publicado en 2015

Prediction of progression to cirrhosis by a glutathione S-transferase P1 polymorphism in subjects with hereditary hemochromatosis

artículo científico publicado en 2005

Predictors of advanced fibrosis in non-cirrhotic non-alcoholic fatty liver disease in Germany

article

Prognosis of a large cohort of patients with hepatocellular carcinoma in a single European centre

artículo científico publicado en 2002

Quantitative testing of liver function compared to prognostic scores in patients with primary biliary cirrhosis

artículo científico publicado en 2002

Reciprocal modulation of matrix metalloproteinase-13 and type I collagen genes in rat hepatic stellate cells

artículo científico publicado en 2003

Reductive Decationizable Block Copolymers for Stimuli-Responsive mRNA Delivery

artículo científico publicado en 2016

Regulation of dipeptidyl peptidase 8 and 9 expression in activated lymphocytes and injured liver.

artículo científico publicado en 2013

Role of the receptor for advanced glycation end products in hepatic fibrosis

artículo científico publicado en 2009

Salivary Gluten Degradation and Oral Microbial Profiles in Healthy Individuals and Celiac Disease Patients

artículo científico publicado en 2017

Salivary proline-rich proteins and gluten: Do structural similarities suggest a role in celiac disease?

artículo científico publicado en 2015

Selective targeting of lysyl oxidase-like 2 (LOXL2) suppresses hepatic fibrosis progression and accelerates its reversal.

artículo científico publicado en 2017

Serum I-FABP Detects Gluten Responsiveness in Adult Celiac Disease Patients on a Short-Term Gluten Challenge

artículo científico publicado en 2016

Serum fibrosis markers to predict clinical and histological progression in hepatitis C non-responders ⬇️

artículo científico publicado el 1 de octubre de 2010

Serum hyaluronate correlates with histological progression in alcoholic liver disease

artículo científico publicado en 2003

Serum markers detect the presence of liver fibrosis: a cohort study

artículo científico publicado en 2004

SiRNA-mediated in vivo gene knockdown by acid-degradable cationic nanohydrogel particles

artículo científico publicado en 2016

Specific hepatic delivery of procollagen α1(I) small interfering RNA in lipid-like nanoparticles resolves liver fibrosis

artículo científico publicado en 2015

Sublethal heat treatment promotes epithelial-mesenchymal transition and enhances the malignant potential of hepatocellular carcinoma

artículo científico publicado en 2013

Synthesis of collagen I in collagenous sprue

artículo científico publicado en 2006

TGF-beta1 codon 25 gene polymorphism is associated with cirrhosis in patients with hereditary hemochromatosis

scientific article published on 01 July 2005

Targeted therapy of liver fibrosis/cirrhosis and its complications ⬇️

artículo científico publicado el 8 de mayo de 2011

Targeting liver fibrosis: strategies for development and validation of antifibrotic therapies.

artículo científico publicado en 2009

Targeting myeloid cells in the tumor sustaining microenvironment

artículo científico publicado en 2017

Targeting the epidermal growth factor receptor by gefitinib for treatment of hepatocellular carcinoma.

artículo científico publicado en 2004

Testing safety of germinated rye sourdough in a celiac disease model based on the adoptive transfer of prolamin-primed memory T cells into lymphopenic mice

artículo científico publicado en 2014

The Incidence and Clinical Spectrum of Refractory Celiac Disease in a North American Referral Center ⬇️

artículo científico publicado el 5 de abril de 2011

The challenge of developing novel pharmacological therapies for non-alcoholic steatohepatitis

artículo científico publicado en 2010

The clinical utility of biomarkers and the nonalcoholic steatohepatitis CRN liver biopsy scoring system in patients with nonalcoholic fatty liver disease

artículo científico publicado en 2009

The elongated first fibronectin type III domain of collagen XIV is an inducer of quiescence and differentiation in fibroblasts and preadipocytes

artículo científico publicado en 2005

The epithelial mitogen keratinocyte growth factor binds to collagens via the consensus sequence glycine-proline-hydroxyproline

artículo científico publicado en 2002

The immune contexture of hepatocellular carcinoma predicts clinical outcome.

artículo científico publicado en 2018

The receptor for advanced glycation end products is highly expressed in the skin and upregulated by advanced glycation end products and tumor necrosis factor-alpha

artículo científico publicado en 2006

Tissue Transglutaminase Does Not Affect Fibrotic Matrix Stability or Regression of Liver Fibrosis in Mice ⬇️

artículo científico publicado el 26 de enero de 2011

Treatment of gastrointestinal neuroendocrine tumors with inhibitors of growth factor receptors and their signaling pathways: recent advances and future perspectives

artículo científico publicado en 2008

Tumour-associated circulating microparticles: A novel liquid biopsy tool for screening and therapy monitoring of colorectal carcinoma and other epithelial neoplasia.

artículo científico publicado en 2016

Turning swords into plowshares: transglutaminase to detoxify gluten

artículo científico publicado en 2007

Update on Serologic Testing in Celiac Disease ⬇️

artículo científico publicado el 1 de diciembre de 2010

Use of HOMA-IR to diagnose non-alcoholic fatty liver disease: a population-based and inter-laboratory study

artículo científico publicado en 2017

VEGF induces proliferation, migration, and TGF-beta1 expression in mouse glomerular endothelial cells via mitogen-activated protein kinase and phosphatidylinositol 3-kinase

artículo científico publicado en 2005

Vascular endothelial growth factor promotes fibrosis resolution and repair in mice

artículo científico publicado en 2014

Voluntary distance running prevents TNF-mediated liver injury in mice through alterations of the intrahepatic immune milieu

artículo científico publicado en 2017

Wheat Consumption Aggravates Colitis in Mice via Amylase Trypsin Inhibitor-mediated Dysbiosis

scientific article published on 03 April 2020

Wheat amylase trypsin inhibitors as nutritional activators of innate immunity

artículo científico

Wheat amylase trypsin inhibitors drive intestinal inflammation via activation of toll-like receptor 4

artículo científico publicado en 2012

Wheat amylase-trypsin inhibitors exacerbate intestinal and airway allergic immune responses in humanized mice

artículo científico publicado en 2018

When GLP-1 hits the liver: a novel approach for insulin resistance and NASH ⬇️

artículo científico publicado el 15 de abril de 2012

α-Mannosyl-Functionalized Cationic Nanohydrogel Particles for Targeted Gene Knockdown in Immunosuppressive Macrophages

artículo científico publicado en 2019

Lista de obras de Detlef Schuppan

3D analysis of microvasculature in murine liver fibrosis models using synchrotron radiation-based microtomography

A change of peginterferon may permit continuation of antiviral therapy in hepatitis C virus-infected patients with interstitial pneumonitis

A key role of GARP in the immune suppressive tumor microenvironment

A quadruple therapy synergistically blocks proliferation and promotes apoptosis of hepatoma cells.

A randomized, placebo-controlled trial of emricasan in patients with NASH and F1-F3 fibrosis

A simple validated gluten-free diet adherence survey for adults with celiac disease

A validated disease-specific symptom index for adults with celiac disease

AMPK regulates macrophage polarization in adipose tissue inflammation and NASH ⬇️

Activation and dramatically increased cytolytic activity of tumor specific T lymphocytes after radio-frequency ablation in patients with hepatocellular carcinoma and colorectal liver metastases

Activation of tumor-specific T lymphocytes by radio-frequency ablation of the VX2 hepatoma in rabbits ⬇️

Acupuncture and Moxibustion in the Treatment of Active Crohn’s Disease: A Randomized Controlled Study

Additive antitumour response to the rabbit VX2 hepatoma by combined radio frequency ablation and toll like receptor 9 stimulation

Adenosine: tipping the balance towards hepatic steatosis and fibrosis

Alcohol dehydrogenase 1C*1 allele is a genetic marker for alcohol-associated cancer in heavy drinkers

Anti-fibrotic therapy: lost in translation?

Anti-tumor necrosis factor-alpha monoclonal antibody therapy in severe alcoholic hepatitis.

Assessment of liver fibrosis progression and regression by a serological collagen turnover profile

Association of myeloperoxidase promotor polymorphism with cirrhosis in patients with hereditary hemochromatosis

Blockade of IGF-1 receptor tyrosine kinase has antineoplastic effects in hepatocellular carcinoma cells

Broad-spectrum matrix metalloproteinase inhibition curbs inflammation and liver injury but aggravates experimental liver fibrosis in mice

CD8+ T cells drive adipose tissue inflammation--a novel clue for NASH pathogenesis?

CFTR dysfunction predisposes to fibrotic liver disease in a murine model ⬇️

Cancer-associated circulating large extracellular vesicles in cholangiocarcinoma and hepatocellular carcinoma.

Celiac disease: from pathogenesis to novel therapies

Changes in hepatic perfusion after administration of hydroxyethyl starch in intensive care patients assessed using color-coded Doppler sonography

Circulating microparticles as disease-specific biomarkers of severity of inflammation in patients with hepatitis C or nonalcoholic steatohepatitis.

Cirrhosis risk score of the donor organ predicts early fibrosis progression after liver transplantation

Combined endostatin/sFlt-1 antiangiogenic gene therapy is highly effective in a rat model of HCC.

Comparison of Gene Expression Patterns Between Mouse Models of Nonalcoholic Fatty Liver Disease and Liver Tissues From Patients

Comparison of murine steatohepatitis models identifies a dietary intervention with robust fibrosis, ductular reaction, and rapid progression to cirrhosis and cancer

Comparison of transient elastography, serum markers and clinical signs for the diagnosis of compensated cirrhosis

Deletion of organic cation transporter Oct3 promotes hepatic fibrosis via upregulation of TGFβ

Dendritic cells in liver injury and fibrosis: Shortcomings and promises ⬇️

Despite sequence homologies to gluten, salivary proline-rich proteins do not elicit immune responses central to the pathogenesis of celiac disease

Dextran-based therapeutic nanoparticles for hepatic drug delivery.

Dietary wheat amylase trypsin inhibitors promote features of murine non-alcoholic fatty liver disease

Disordered pancreatic inflammatory responses and inhibition of fibrosis in CD39-null mice

Early changes in dynamic biomarkers of liver fibrosis in hepatitis C virus-infected patients treated with sofosbuvir

Elevated transaminases as a predictor of coma in a patient with anorexia nervosa: a case report and review of the literature

Endostatin competes with bFGF for binding to heparin-like glycosaminoglycans

Endothelin-1 enhances fibrogenic gene expression, but does not promote DNA synthesis or apoptosis in hepatic stellate cells

Enhanced liver fibrosis test for the non-invasive diagnosis of fibrosis in patients with NAFLD: A systematic review and meta-analysis

Enhanced protection of C57 BL/6 vs Balb/c mice to melanoma liver metastasis is mediated by NK cells.

Epithelial-to-mesenchymal transition in liver fibrosis: dead or alive?

Etiologies and predictors of diagnosis in nonresponsive celiac disease

Extrahepatic platelet-derived growth factor-β, delivered by platelets, promotes activation of hepatic stellate cells and biliary fibrosis in mice

Factors that influence adherence to a gluten-free diet in adults with celiac disease

Failure of Fibrotic Liver Regeneration in Mice Is Linked to a Severe Fibrogenic Response Driven by Hepatic Progenitor Cell Activation ⬇️

Fibroblast growth factor 21 limits lipotoxicity by promoting hepatic fatty acid activation in mice on methionine and choline-deficient diets

Fibrosis evaluation by transient elastography in alcoholic liver disease: Is the histological scoring system impacting cutoff values?

Gliptins Suppress Inflammatory Macrophage Activation to Mitigate Inflammation, Fibrosis, Oxidative Stress, and Vascular Dysfunction in Models of Nonalcoholic Steatohepatitis and Liver Fibrosis

Growth factor receptors and related signalling pathways as targets for novel treatment strategies of hepatocellular cancer

Gut-CNS-Axis as Possibility to Modulate Inflammatory Disease Activity-Implications for Multiple Sclerosis

HIV and HCV cooperatively promote hepatic fibrogenesis via induction of reactive oxygen species and NFkappaB

Halofuginone induces matrix metalloproteinases in rat hepatic stellate cells via activation of p38 and NFkappaB.

Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans

Helicobacter pylori upregulates prion protein expression in gastric mucosa: a possible link to prion disease.

Hepatic B cell leukemia-3 promotes hepatic steatosis and inflammation through insulin-sensitive metabolic transcription factors

Hepatic fibrosis: Concept to treatment

Hepatic fibrosis: from bench to bedside

Hepatitis C virus-replicating hepatocytes induce fibrogenic activation of hepatic stellate cells.

Hepatitis C virus-specific T-cell-derived transforming growth factor beta is associated with slow hepatic fibrogenesis

Hepatitis induced by Kava (Piper methysticum rhizoma)

Hepatocellular carcinoma in nonalcoholic fatty liver disease: A link between oxidative stress and T-cell suppression

Hepatocellular carcinomas do not compromise quantitative tests of liver function

Hepatocyte growth factor and c-Met expression in rat and human liver fibrosis.

Hepatocyte transplantation activates hepatic stellate cells with beneficial modulation of cell engraftment in the rat.

Hepatotoxicity of alcohol-induced polar retinol metabolites involves apoptosis via loss of mitochondrial membrane potential.

Herbal hepatotoxicity

Histone deacetylase inhibitor MS-275 alone or combined with bortezomib or sorafenib exhibits strong antiproliferative action in human cholangiocarcinoma cells

Human T cell microparticles circulate in blood of hepatitis patients and induce fibrolytic activation of hepatic stellate cells.

Human risk allele HLA-DRB1*0405 predisposes class II transgenic Ab0 NOD mice to autoimmune pancreatitis

Hydroxyproline-containing collagen analogs trigger the release and activation of collagen-sequestered proMMP-2 by competition with prodomain-derived peptide P33-42.

Hypoxia-inducible factor 1 alpha under rapid enzymatic hypoxia: cells sense decrements of oxygen but not hypoxia per se.

IL-4 Receptor Alpha Signaling through Macrophages Differentially Regulates Liver Fibrosis Progression and Reversal.

IL28B genotype is associated with differential expression of intrahepatic interferon-stimulated genes in patients with chronic hepatitis C.

In Vivo Gene-Silencing in Fibrotic Liver by siRNA-Loaded Cationic Nanohydrogel Particles

In Vivo siRNA Delivery to Immunosuppressive Liver Macrophages by α-Mannosyl-Functionalized Cationic Nanohydrogel Particles

In vitro differentiation of human monocytes into dendritic cells by peptic-tryptic digest of gliadin is independent of genetic predisposition and the presence of celiac disease.