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Lista de obras de Rudolph E. Tanzi

3D culture models of Alzheimer's disease: a road map to a "cure-in-a-dish"

artículo científico publicado en 2016

A 3D human neural cell culture system for modeling Alzheimer's disease

artículo científico publicado en 2015

A 3D human triculture system modeling neurodegeneration and neuroinflammation in Alzheimer's disease

artículo científico publicado en 2018

A Brief History of Alzheimer's Disease Gene Discovery ⬇️

artículo científico publicado el 1 de enero de 2013

A Circadian Clock Gene, Cry, Affects Heart Morphogenesis and Function in Drosophila as Revealed by Optical Coherence Microscopy

artículo científico publicado en 2015

A Curcumin Analog Reduces Levels of the Alzheimer's Disease-Associated Amyloid-β Protein by Modulating AβPP Processing and Autophagy

artículo científico publicado en 2019

A Multidisciplinary Approach to Mind and Consciousness

artículo científico publicado en 2013

A current view of Alzheimer's disease ⬇️

artículo científico publicado el 8 de julio de 2009

A three-dimensional human neural cell culture model of Alzheimer's disease

artículo científico publicado en 2014

A γ-secretase inhibitor, but not a γ-secretase modulator, induced defects in BDNF axonal trafficking and signaling: evidence for a role for APP

artículo científico publicado en 2015

ADAM10 Missense Mutations Potentiate β-Amyloid Accumulation by Impairing Prodomain Chaperone Function ⬇️

artículo científico publicado el 19 de septiembre de 2013

APP substitutions V715F and L720P alter PS1 conformation and differentially affect Abeta and AICD generation

artículo científico publicado en 2005

Adjusting heterogeneous ascertainment bias for genetic association analysis with extended families

artículo científico publicado en 2015

Age-dependent effect of apolipoprotein E4 on functional outcome after controlled cortical impact in mice

artículo científico publicado en 2010

Age-dependent postoperative cognitive impairment and Alzheimer-related neuropathology in mice

artículo científico publicado en 2014

Age-dependent, non-cell-autonomous deposition of amyloid from synthesis of β-amyloid by cells other than excitatory neurons

artículo científico publicado en 2014

Altered hippocampal gene expression 2 days after general anesthesia in rats

artículo científico publicado en 2006

Alternatives to amyloid for Alzheimer's disease therapies-a symposium report

artículo científico publicado en 2020

Alzheimer disease risk genes: 29 and counting

artículo científico publicado en 2019

Alzheimer disease: New light on an old CLU.

artículo científico publicado en 2010

Alzheimer's Disease-Associated β-Amyloid Is Rapidly Seeded by Herpesviridae to Protect against Brain Infection

Alzheimer's Disease-Associated β-Amyloid Is Rapidly Seeded by Herpesviridae to Protect against Brain Infection

scientific article published on 01 December 2018

Alzheimer's disease amyloid-beta links lens and brain pathology in Down syndrome

artículo científico publicado en 2010

Alzheimer's disease and post-operative cognitive dysfunction

artículo científico publicado en 2006

Alzheimer's disease drug discovery targeted to the APP mRNA 5'untranslated region

artículo científico publicado en 2002

Alzheimer's disease risk gene CD33 inhibits microglial uptake of amyloid beta

artículo científico publicado en 2013

Alzheimer's disease-associated TREM2 variants exhibit either decreased or increased ligand-dependent activation.

artículo científico publicado en 2016

Alzheimer's disease-associated ubiquilin-1 regulates presenilin-1 accumulation and aggresome formation

artículo científico publicado en 2011

Alzheimer's disease: The latest suspect

artículo científico publicado en 2008

Alzheimer's disease: one disorder, too many genes?

artículo científico publicado en 2004

Alzheimer's disease: the cholesterol connection

artículo científico publicado en 2003

Alzheimer's disease: the potential therapeutic role of the natural antibiotic amyloid-β peptide

artículo científico publicado en 2016

Alzheimer's in 3D culture: challenges and perspectives

artículo científico publicado en 2015

Amyloid-β Production Via Cleavage of Amyloid-β Protein Precursor is Modulated by Cell Density ⬇️

artículo científico publicado el 1 de enero de 2010

Amyloid-β peptide protects against microbial infection in mouse and worm models of Alzheimer's disease

artículo científico publicado en 2016

Amyloid-β42/40 ratio drives tau pathology in 3D human neural cell culture models of Alzheimer's disease

scientific article published on 13 March 2020

An AICD-based functional screen to identify APP metabolism regulators.

artículo científico publicado en 2007

An iron-responsive element type II in the 5'-untranslated region of the Alzheimer's amyloid precursor protein transcript

artículo científico publicado en 2002

Anesthetic propofol attenuates the isoflurane-induced caspase-3 activation and Aβ oligomerization

artículo científico publicado en 2011

Anesthetics isoflurane and desflurane differently affect mitochondrial function, learning, and memory

artículo científico publicado en 2012

Antibiotic-induced perturbations in gut microbial diversity influences neuro-inflammation and amyloidosis in a murine model of Alzheimer's disease

artículo científico publicado en 2016

Antibiotic-induced perturbations in microbial diversity during post-natal development alters amyloid pathology in an aged APPSWE/PS1ΔE9 murine model of Alzheimer's disease

artículo científico publicado en 2017

Artefactual effects of lipid-based cell transfection reagents on AbetaPP processing and Abeta production

artículo científico publicado en 2006

Assessment of Alzheimer's disease case-control associations using family-based methods

artículo científico publicado en 2009

Association between microdeletion and microduplication at 16p11.2 and autism

artículo científico publicado en 2008

Association of GSK3B with Alzheimer disease and frontotemporal dementia

artículo científico publicado en 2008

Association of UBQLN1 mutation with Brown–Vialetto–Van Laere syndrome but not typical ALS ⬇️

artículo científico publicado el 3 de julio de 2012

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 01 September 2019

Autoantibodies to redox-modified oligomeric Abeta are attenuated in the plasma of Alzheimer's disease patients

artículo científico publicado en 2005

Aβ-accelerated neurodegeneration caused by Alzheimer's-associated ACE variant R1279Q is rescued by angiotensin system inhibition in mice

scientific article published on 01 September 2020

BACE is degraded via the lysosomal pathway

artículo científico publicado en 2005

Brown adipose tissue-derived MaR2 contributes to cold-induced resolution of inflammation

artículo científico publicado en 2022

CALHM1 P86L polymorphism does not alter amyloid-beta or tau in cerebrospinal fluid

artículo científico publicado en 2009

Caspase activation increases beta-amyloid generation independently of caspase cleavage of the beta-amyloid precursor protein (APP).

artículo científico publicado en 2003

Cathepsin L Mediates the Degradation of Novel APP C-Terminal Fragments.

artículo científico publicado en 2015

Cerebrospinal fluid aβ to tau ratio and postoperative cognitive change

artículo científico publicado en 2013

Change in Sense of Nondual Awareness and Spiritual Awakening in Response to a Multidimensional Well-Being Program.

artículo científico publicado en 2017

Characterization of the precursor protein of the non-A beta component of senile plaques (NACP) in the human central nervous system

artículo científico publicado en 1996

Characterizing Gene and Protein Crosstalks in Subjects at Risk of Developing Alzheimer’s Disease: A New Computational Approach

article

Chronic traumatic encephalopathy in blast-exposed military veterans and a blast neurotrauma mouse model.

artículo científico publicado en 2012

Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer's mouse model

artículo científico publicado en 2018

Comment on "ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models".

artículo científico publicado en 2013

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

artículo científico publicado en 2011

Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database

artículo científico publicado en 2012

Copper, beta-amyloid, and Alzheimer's disease: tapping a sensitive connection

artículo científico publicado en 2003

Correction to Cathepsin L Mediates the Degradation of Novel APP C-Terminal Fragments.

artículo científico publicado en 2015

Correction: The Zinc Dyshomeostasis Hypothesis of Alzheimer's Disease

artículo científico publicado en 2013

Correction: The Zinc Dyshomeostasis Hypothesis of Alzheimer's Disease.

artículo científico publicado en 2012

Correction: The Zinc Dyshomeostasis Hypothesis of Alzheimer'sDisease

artículo científico publicado en 2012

Correspondence to Sand et al. “Critical Reappraisal of a Catechol-O-Methyltransferase Transversion Variant in Schizophrenia”

article by Christina M. Lill et al published April 2010 in Biological Psychiatry

Corrigendum: Identification of Altered Metabolomic Profiles Following a Panchakarma-based Ayurvedic Intervention in Healthy Subjects: The Self-Directed Biological Transformation Initiative (SBTI)

artículo científico publicado en 2016

Cromolyn Reduces Levels of the Alzheimer's Disease-Associated Amyloid β-Protein by Promoting Microglial Phagocytosis

artículo científico publicado en 2018

Cromolyn sodium delays disease onset and is neuroprotective in the SOD1G93A Mouse Model of amyotrophic lateral sclerosis

scientific article published on 27 November 2019

Curcumin decreases amyloid-beta peptide levels by attenuating the maturation of amyloid-beta precursor protein.

artículo científico publicado en 2010

Cysteine 27 variant of the delta-opioid receptor affects amyloid precursor protein processing through altered endocytic trafficking

artículo científico publicado en 2011

Cytokine-mediated inflammation mediates painful neuropathy from metabolic syndrome

artículo científico publicado en 2018

Cytosolic beta-amyloid deposition and supranuclear cataracts in lenses from people with Alzheimer's disease

artículo científico publicado en 2003

Decreased catalytic activity of the insulin-degrading enzyme in chromosome 10-linked Alzheimer disease families

artículo científico publicado en 2007

Depletion of GGA3 stabilizes BACE and enhances beta-secretase activity

artículo científico publicado en 2007

Design and synthesis of aminothiazole modulators of the gamma-secretase enzyme

artículo científico publicado en 2016

Design and synthesis of novel methoxypyridine-derived gamma-secretase modulators

scientific article published on 01 September 2020

Diabetes-associated SorCS1 regulates Alzheimer's amyloid-beta metabolism: evidence for involvement of SorL1 and the retromer complex

artículo científico publicado en 2010

Drosophila Preparation and Longitudinal Imaging of Heart Function In Vivo Using Optical Coherence Microscopy (OCM)

artículo científico publicado en 2016

Effect of potent γ-secretase modulator in human neurons derived from multiple presenilin 1-induced pluripotent stem cell mutant carriers

artículo científico publicado en 2014

Effects of RNA interference-mediated silencing of gamma-secretase complex components on cell sensitivity to caspase-3 activation

artículo científico publicado en 2004

Effects of RNAi-mediated silencing of PEN-2, APH-1a, and nicastrin on wild-type vs FAD mutant forms of presenilin 1.

artículo científico publicado en 2005

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study

artículo científico publicado en 2014

Effects of ubiquilin 1 on the unfolded protein response

artículo científico publicado en 2008

Elucidation of the BACE1 regulating factor GGA3 in Alzheimer's disease

artículo científico publicado en 2013

Emerging role of Alzheimer's disease-associated ubiquilin-1 in protein aggregation

artículo científico publicado en 2010

Endotype reversal as a novel strategy for screening drugs targeting familial Alzheimer's disease

artículo científico

Evaluation of the potential excess of statistically significant findings in published genetic association studies: application to Alzheimer's disease

artículo científico publicado en 2008

Evidence of altered posteromedial cortical FMRI activity in subjects at risk for Alzheimer disease

artículo científico publicado en 2010

Exploring candidate gene associations with neuropsychological performance

scientific article published on 01 December 2007

Familial Alzheimer's disease mutations in presenilin 1 do not alter levels of the secreted amyloid-beta protein precursor generated by beta-secretase cleavage

artículo científico publicado en 2010

Family-based association between Alzheimer's disease and variants in UBQLN1

artículo científico publicado en 2005

FlyNet 2.0: drosophila heart 3D (2D + time) segmentation in optical coherence microscopy images using a convolutional long short-term memory neural network

artículo científico publicado en 2020

Follow-up mapping supports the evidence for linkage in the candidate region at 9q22 in the NIMH Alzheimer's disease Genetics Initiative cohort

artículo científico publicado en 2007

Functional Links Between Aβ Toxicity, Endocytic Trafficking, and Alzheimer’s Disease Risk Factors in Yeast ⬇️

artículo científico publicado el 27 de octubre de 2011

GAB2 as an Alzheimer disease susceptibility gene: follow-up of genomewide association results

artículo científico publicado en 2009

GENETICS. The Human Variome Project

artículo científico publicado en 2008

Gain-of-function mutations in protein kinase Cα (PKCα) may promote synaptic defects in Alzheimer's disease

scientific article published on 10 May 2016

Gene therapy for Alzheimer's Disease targeting CD33 reduces amyloid beta accumulation and neuroinflammation

scientific article published on 17 August 2020

Generation of the β-Amyloid Peptide and the Amyloid Precursor Protein C-terminal Fragment γ Are Potentiated by FE65L1 ⬇️

artículo científico publicado el 3 de octubre de 2003

Genetic association of Alzheimer's disease with multiple polymorphisms in alpha-2-macroglobulin

artículo científico publicado en 2003

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

artículo científico publicado en 2019

Genome-wide association analysis reveals putative Alzheimer's disease susceptibility loci in addition to APOE.

artículo científico publicado en 2008

Genome-wide association study of Alzheimer's disease CSF biomarkers in the EMIF-AD Multimodal Biomarker Discovery dataset

artículo científico publicado en 2020

Genome-wide linkage analysis of 723 affected relative pairs with late-onset Alzheimer's disease

article

Gga3 deletion and a GGA3 rare variant associated with late onset Alzheimer's disease trigger BACE1 accumulation in axonal swellings

artículo científico publicado en 2020

HtrA2 regulates beta-amyloid precursor protein (APP) metabolism through endoplasmic reticulum-associated degradation

artículo científico publicado en 2007

Human Neurospheroid Arrays for In Vitro Studies of Alzheimer's Disease

artículo científico publicado en 2018

Human amyloid-derived aßcontains tyrosine cross-linked oligomers

article published in 2000

Hypocapnia induces caspase-3 activation and increases Abeta production

artículo científico publicado en 2004

Hypoxic ischemia and proteasome dysfunction alter tau isoform ratio by inhibiting exon 10 splicing

artículo científico

Identification of Altered Metabolomic Profiles Following a Panchakarma-based Ayurvedic Intervention in Healthy Subjects: The Self-Directed Biological Transformation Initiative (SBTI).

artículo científico publicado en 2016

Identification of NEEP21 as a β-Amyloid Precursor Protein-Interacting ProteinIn VivoThat Modulates Amyloidogenic ProcessingIn Vitro ⬇️

artículo científico publicado el 17 de noviembre de 2010

Identification of Novel Alzheimer's Disease Loci Using Sex-Specific Family-Based Association Analysis of Whole-Genome Sequence Data

scientific article published on 19 March 2020

Identification of clusters of rapid and slow decliners among subjects at risk for Alzheimer's disease

artículo científico publicado en 2017

In Vivo Quasi-Elastic Light Scattering Eye Scanner Detects Molecular Aging in Humans

artículo científico publicado en 2020

Inhibition of death-associated protein kinase 1 attenuates the phosphorylation and amyloidogenic processing of amyloid precursor protein

artículo científico publicado en 2016

Insulin-degrading enzyme is genetically associated with Alzheimer's disease in the Finnish population

artículo científico publicado en 2007

Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo

artículo científico publicado en 2003

Interaction between presenilin 1 and ubiquilin 1 as detected by fluorescence lifetime imaging microscopy and a high-throughput fluorescent plate reader

artículo científico publicado en 2006

Involvement of ubiquilin-1 transcript variants in protein degradation and accumulation

artículo científico

Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's disease

artículo científico publicado en 2010

Is Alzheimer's Disease a Neurogenesis Disorder?

scientific article published on 01 July 2019

Is alpha-T catenin (VR22) an Alzheimer's disease risk gene?

artículo científico publicado en 2007

Isoflurane decreases self-renewal capacity of rat cultured neural stem cells

artículo científico publicado en 2011

Isoflurane-induced apoptosis: a potential pathogenic link between delirium and dementia

artículo científico publicado en 2006

Isoflurane-induced caspase-3 activation is dependent on cytosolic calcium and can be attenuated by memantine

artículo científico publicado en 2008

Isolation and characterization of the Drosophila ubiquilin ortholog dUbqln: in vivo interaction with early-onset Alzheimer disease genes

artículo científico publicado en 2007

LRP-mediated clearance of Abeta is inhibited by KPI-containing isoforms of APP.

artículo científico publicado en 2005

Lack of hepatic apoE does not influence early Aβ deposition: observations from a new APOE knock-in model

scientific article published on 17 October 2019

Longitudinal change in cognitive performance among individuals with mild cognitive impairment

artículo científico publicado en 2007

Loss of Ataxin-1 Potentiates Alzheimer's Pathogenesis by Elevating Cerebral BACE1 Transcription

scientific article published on 01 August 2019

Loss of function of ATXN1 increases amyloid beta-protein levels by potentiating beta-secretase processing of beta-amyloid precursor protein.

artículo científico publicado en 2010

Low Evolutionary Selection Pressure in Senescence Does Not Explain the Persistence of Aβ in the Vertebrate Genome

Low-density lipoprotein receptor-related protein levels and endocytic function are reduced by overexpression of the FE65 adaptor protein, FE65L1.

artículo científico publicado en 2002

Magnetic resonance imaging white matter hyperintensities and brain volume in the prediction of mild cognitive impairment and dementia.

artículo científico publicado en 2008

Mapping autism risk loci using genetic linkage and chromosomal rearrangements

artículo científico publicado en 2007

Massachusetts Alzheimer's Disease Research Center: progress and challenges

artículo científico publicado en 2015

Maximizing the Power of Genome-Wide Association Studies: A Novel Class of Powerful Family-Based Association Tests ⬇️

artículo científico publicado el 1 de noviembre de 2009

Mechanisms that synergistically regulate η-secretase processing of APP and Aη-α protein levels: relevance to pathogenesis and treatment of Alzheimer's disease

artículo científico publicado en 2017

Meditation and Yoga Practices as Potential Adjunctive Treatment of SARS-CoV-2 Infection and COVID-19: A Brief Overview of Key Subjects

artículo científico publicado en 2020

Metal exposure and Alzheimer's pathogenesis.

artículo científico publicado en 2006

Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial

artículo científico publicado en 2003

Metalloenzyme-like activity of Alzheimer's disease beta-amyloid. Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H(2)O(2).

artículo científico publicado en 2002

Modulation of gamma-secretase reduces beta-amyloid deposition in a transgenic mouse model of Alzheimer's disease

artículo científico publicado en 2010

Molecular imaging of Alzheimer's disease-related gamma-secretase in mice and nonhuman primates

scientific article published on 01 December 2020

Nanoplasmonic fiber tip probe detects significant reduction of intracellular Alzheimer's disease-related oligomers by curcumin

artículo científico publicado en 2017

Near-infrared fluorescence molecular imaging of amyloid beta species and monitoring therapy in animal models of Alzheimer's disease

artículo científico publicado en 2015

Negative evidence for a role of APH1B T27I variant in Alzheimer's disease

scientific article published on 29 January 2020

Neuroinflammatory Environments Promote Amyloid-β Deposition and Posttranslational Modification

Neuroinflammatory Responses in the Alzheimer's Disease Brain Promote the Oxidative Post-translational Modification of Amyloid Deposits

article

Neuropsychological measures in normal individuals that predict subsequent cognitive decline.

artículo científico publicado en 2007

No association between CALHM1 and Alzheimer's disease risk

artículo científico publicado en 2008

Non-invasive red-light optogenetic control of Drosophila cardiac function

artículo científico publicado en 2020

Novel late-onset Alzheimer disease loci variants associate with brain gene expression

artículo científico publicado en 2012

On the Meta-Analysis of Genome-Wide Association Studies: A Robust and Efficient Approach to Combine Population and Family-Based Studies ⬇️

artículo científico publicado el 18 de enero de 2012

On the association analysis of genome-sequencing data: A spatial clustering approach for partitioning the entire genome into nonoverlapping windows.

artículo científico publicado en 2017

Optical Coherence Tomography for Brain Imaging and Developmental Biology

artículo científico publicado en 2015

Optogenetic pacing in Drosophila melanogaster

artículo científico publicado en 2015

P1-131 (Aβ) in human lens & aqueous humor: further characterization of a novel AD biomarker

PBT2 rapidly improves cognition in Alzheimer's Disease: additional phase II analyses

artículo científico publicado en 2010

PLD3 gene variants and Alzheimer's disease

artículo científico publicado en 2015

Palmitoylated APP Forms Dimers, Cleaved by BACE1.

artículo científico publicado en 2016

Partial loss-of-function mutations in insulin-degrading enzyme that induce diabetes also impair degradation of amyloid beta-protein

artículo científico publicado en 2004

Peripheral surgical wounding and age-dependent neuroinflammation in mice

artículo científico publicado en 2014

Peroxidase activity of cyclooxygenase-2 (COX-2) cross-links beta-amyloid (Abeta) and generates Abeta-COX-2 hetero-oligomers that are increased in Alzheimer's disease

artículo científico publicado en 2004

Pharmacological and Toxicological Properties of the Potent Oral γ-Secretase Modulator BPN-15606.

artículo científico publicado en 2017

Potential Use of γ-Secretase Modulators in the Treatment of Alzheimer Disease ⬇️

artículo científico publicado el 1 de octubre de 2012

Potential late-onset Alzheimer's disease-associated mutations in the ADAM10 gene attenuate {alpha}-secretase activity

artículo científico publicado en 2009

Potential therapeutic targets for Alzheimer’s disease

Preliminary studies of a novel bifunctional metal chelator targeting Alzheimer's amyloidogenesis

artículo científico publicado en 2004

Protein aggregates and novel presenilin gene variants in idiopathic dilated cardiomyopathy

artículo científico publicado en 2010

RNA interference silencing of the adaptor molecules ShcC and Fe65 differentially affect amyloid precursor protein processing and Abeta generation

artículo científico publicado en 2006

RNA interference-mediated silencing of X11alpha and X11beta attenuates amyloid beta-protein levels via differential effects on beta-amyloid precursor protein processing.

artículo científico publicado en 2005

RNAi-mediated knock-down of Dab and Numb attenuate Aβ levels via γ-secretase mediated APP processing ⬇️

artículo científico publicado el 22 de marzo de 2012

Rapid restoration of cognition in Alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Abeta

artículo científico publicado en 2008

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

artículo científico publicado en 2017

Rarity of the Alzheimer disease-protective APP A673T variant in the United States

artículo científico publicado en 2015

Recapitulating amyloid β and tau pathology in human neural cell culture models: clinical implications

artículo científico publicado en 2015

Recovering unused information in genome-wide association studies: the benefit of analyzing SNPs out of Hardy-Weinberg equilibrium

artículo científico publicado en 2009

Redox-active metals, oxidative stress, and Alzheimer's disease pathology

artículo científico publicado en 2004

Reduced amyloidogenic processing of the amyloid beta-protein precursor by the small-molecule Differentiation Inducing Factor-1

artículo científico publicado en 2008

Region-based analysis of rare genomic variants in whole-genome sequencing datasets reveal two novel Alzheimer's disease-associated genes: DTNB and DLG2

artículo científico publicado en 2022

Regulation of key proteins in Alzheimer’s disease molecular pathogenesis by ubiquilin-1

Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models

artículo científico publicado en 2015

Relationships among classifications of ayurvedic medicine diagnostics for imbalances (vikruti) and western measures of psychological states: An exploratory study

artículo científico publicado en 2018

Relevance of the COPI complex for Alzheimer's disease progression in vivo

artículo científico publicado en 2016

Response to Mancuso et al.: Curcumin and Alzheimer Disease: This Marriage Is Not to Be Performed

artículo científico publicado en 2011

Results of a high-resolution genome screen of 437 Alzheimer's disease families

artículo científico publicado en 2003

SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC)

artículo científico publicado en 2023

SUMO1 modulates Aβ generation via BACE1 accumulation.

artículo científico publicado en 2012

Science Signaling Podcast for 10 May 2016: PKCα in Alzheimer's disease

artículo científico publicado en 2016

Segmentation of Drosophila heart in optical coherence microscopy images using convolutional neural networks

scientific article published on 06 August 2018

Sex Differences in Cognitive Decline in Subjects with High Likelihood of Mild Cognitive Impairment due to Alzheimer's disease

artículo científico publicado en 2018

Significant Upregulation of Alzheimer's β-Amyloid Levels in a Living System Induced by Extracellular Elastin Polypeptides

artículo científico publicado en 2019

Silencing of the Drosophila ortholog of SOX5 in heart leads to cardiac dysfunction as detected by optical coherence tomography ⬇️

artículo científico publicado el 21 de mayo de 2013

Silencing of the Drosophila ortholog of SOX5 leads to abnormal neuronal development and behavioral impairment

artículo científico publicado en 2017

Single-nucleotide polymorphism rs498055 on chromosome 10q24 is not associated with Alzheimer disease in two independent family samples

artículo científico publicado en 2006

Soluble Gamma-secretase Modulators Attenuate Alzheimer's β-amyloid Pathology and Induce Conformational Changes in Presenilin 1.

artículo científico publicado en 2017

Soluble γ-secretase modulators selectively inhibit the production of the 42-amino acid amyloid β peptide variant and augment the production of multiple carboxy-truncated amyloid β species

artículo científico publicado en 2014

Spatial memory is intact in aged rats after propofol anesthesia

artículo científico publicado en 2008

Synaptotagmins interact with APP and promote Aβ generation

artículo científico publicado en 2015

Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database

artículo científico publicado en 2008

Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database

artículo científico publicado en 2007

TREM2 Acts Downstream of CD33 in Modulating Microglial Pathology in Alzheimer's Disease

artículo científico publicado en 2019

TREM2 and Risk of Alzheimer's Disease--Friend or Foe?

artículo científico publicado en 2015

Tangles and neurodegenerative disease--a surprising twist

artículo científico publicado en 2005

Targeting ubiquilin-1 in Alzheimer's disease

artículo científico

Tau molecular diversity contributes to clinical heterogeneity in Alzheimer's disease

artículo científico publicado en 2020

The Alzheimer's disease-associated amyloid beta-protein is an antimicrobial peptide

artículo científico publicado en 2010

The Amazon rain forest plant Uncaria tomentosa (cat's claw) and its specific proanthocyanidin constituents are potent inhibitors and reducers of both brain plaques and tangles

artículo científico publicado en 2019

The CALHM1 P86L polymorphism is a genetic modifier of age at onset in Alzheimer's disease: a meta-analysis study

artículo científico publicado en 2010

The LDLR locus in Alzheimer's disease: a family-based study and meta-analysis of case-control data

artículo científico publicado en 2005

The Self-Directed Biological Transformation Initiative and Well-Being

artículo científico publicado en 2016

The antimicrobial protection hypothesis of Alzheimer's disease

article

The common inhalation anesthetic isoflurane induces apoptosis and increases amyloid beta protein levels

artículo científico publicado en 2006

The common inhalation anesthetic isoflurane induces caspase activation and increases amyloid beta-protein level in vivo

artículo científico publicado en 2008

The common inhalational anesthetic sevoflurane induces apoptosis and increases beta-amyloid protein levels

artículo científico publicado en 2009

The current status of Alzheimer's disease genetics: what do we tell the patients?

artículo científico publicado en 2004

The effects of isoflurane and desflurane on cognitive function in humans

artículo científico publicado en 2011

The galvanization of beta-amyloid in Alzheimer's disease

artículo científico publicado en 2002

The genetic epidemiology of neurodegenerative disease

artículo científico publicado en 2005

The genetics of Alzheimer disease: back to the future

artículo científico publicado en 2010

The genetics of Alzheimer's disease

artículo científico publicado en 2012

The inhalation anesthetic desflurane induces caspase activation and increases amyloid beta-protein levels under hypoxic conditions

artículo científico publicado en 2008

The inhalation anesthetic isoflurane increases levels of proinflammatory TNF-α, IL-6, and IL-1β.

artículo científico publicado en 2010

The rare TREM2 R47H variant exerts only a modest effect on Alzheimer disease risk.

artículo científico publicado en 2014

The role of clusterin, complement receptor 1, and phosphatidylinositol binding clathrin assembly protein in Alzheimer disease risk and cerebrospinal fluid biomarker levels

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