Filtros de búsqueda

Lista de obras de Sheena Radford

2-Oxo acid dehydrogenase multi-enzyme complexes: in the beginning and halfway there.

artículo científico publicado en 1987

A Population Shift between Sparsely Populated Folding Intermediates Determines Amyloidogenicity ⬇️

artículo científico publicado en 2016

A Structural Model for Apolipoprotein C-II Amyloid Fibrils: Experimental Characterization and Molecular Dynamics Simulations

artículo científico publicado en 2011

A common beta-sheet architecture underlies in vitro and in vivo beta2-microglobulin amyloid fibrils ⬇️

artículo científico publicado en 2008

A comparison of the folding characteristics of free and ribosome-tethered polypeptide chains using limited proteolysis and mass spectrometry ⬇️

artículo científico publicado en 2015

A diversity of assembly mechanisms of a generic amyloid fold

artículo científico publicado en 2011

A force-activated trip switch triggers rapid dissociation of a colicin from its immunity protein

artículo científico publicado en 2013

A generic mechanism of beta2-microglobulin amyloid assembly at neutral pH involving a specific proline switch.

artículo científico publicado en 2009

A growing toolbox of techniques for studying β-barrel outer membrane protein folding and biogenesis ⬇️

artículo científico publicado en 2016

A mutant pyruvate dehydrogenase complex of Escherichia coli deleted in the (alanine + proline)-rich region of the acetyltransferase component

artículo científico publicado en 1987

A near-native state on the slow refolding pathway of hen lysozyme.

artículo científico publicado en 1999

A new era for understanding amyloid structures and disease ⬇️

artículo científico publicado en 2018

A partially folded intermediate species of the beta-sheet protein apo-pseudoazurin is trapped during proline-limited folding

artículo científico publicado en 2001

A partially folded state of hen egg white lysozyme in trifluoroethanol: structural characterization and implications for protein folding

artículo científico publicado en 1993

A peptide-display protein scaffold to facilitate single molecule force studies of aggregation-prone peptides ⬇️

artículo científico publicado en 2018

A photochemically induced dynamic nuclear polarization study of denatured state of lysozyme

artículo científico publicado en 1991

A short motif in the N-terminal region of α-synuclein is critical for both aggregation and function

artículo científico publicado en 2020

A study of D52S hen lysozyme-GlcNAc oligosaccharide complexes by NMR spectroscopy and electrospray mass spectrometry

artículo científico publicado en 1992

A systematic investigation into the effect of protein destabilisation on beta 2-microglobulin amyloid formation

artículo científico publicado en 2003

A systematic study of the effect of physiological factors on beta2-microglobulin amyloid formation at neutral pH.

artículo científico publicado en 2006

A tale of a tail: Structural insights into the conformational properties of the polyglutamine protein ataxin-3. ⬇️

artículo científico publicado en 2013

A three-disulphide derivative of hen lysozyme. Structure, dynamics and stability

artículo científico publicado en 1991

Acceleration of the folding of hen lysozyme by trifluoroethanol

artículo científico publicado en 1997

Accurate Use of Single Molecule Fluorescence Correlation Spectroscopy to Determine Molecular Diffusion Times

article published in 2001

Acidic conditions stabilise intermediates populated during the folding of Im7 and Im9.

artículo científico publicado en 2001

Advances in ion mobility spectrometry-mass spectrometry reveal key insights into amyloid assembly

artículo científico publicado en 2013

Aggregation modulators interfere with membrane interactions of β2-microglobulin fibrils ⬇️

artículo científico publicado en 2013

Amide hydrogen exchange in a highly denatured state. Hen egg-white lysozyme in urea

artículo científico publicado en 1994

Amino Acid Insertion Reveals a Necessary Three-Helical Intermediate in the Folding Pathway of the Colicin E7 Immunity Protein Im7

artículo científico publicado en 2009

Amphipathic polymers enable the study of functional membrane proteins in the gas phase ⬇️

artículo científico publicado en 2012

Amphipols outperform dodecylmaltoside micelles in stabilizing membrane protein structure in the gas phase ⬇️

artículo científico publicado en 2014

Amyloid Fibres: Inert End-Stage Aggregates or Key Players in Disease? ⬇️

artículo científico publicado en 2015

Amyloid fibril length distribution quantified by atomic force microscopy single-particle image analysis ⬇️

artículo científico publicado en 2009

Amyloid formation under physiological conditions proceeds via a native-like folding intermediate

artículo científico publicado en 2006

Amyloid plaques beyond Aβ: a survey of the diverse modulators of amyloid aggregation ⬇️

artículo científico publicado en 2017

Amyloid structures: much more than just a cross-β fold

scientific article published on 01 November 2019

Amyloid under the atomic force microscope

artículo científico publicado en 2006

Amyloid-forming peptides from beta2-microglobulin-Insights into the mechanism of fibril formation in vitro

artículo científico publicado en 2003

An expanding arsenal of experimental methods yields an explosion of insights into protein folding mechanisms

artículo científico publicado en 2009

An imaging and systems modeling approach to fibril breakage enables prediction of amyloid behavior ⬇️

artículo científico publicado en 2013

An in vivo platform for identifying inhibitors of protein aggregation ⬇️

artículo científico publicado en 2015

An in vivo platform to select and evolve aggregation-resistant proteins

scientific article published on 14 April 2020

Analysis of amyloid nanostructures using photo-cross-linking: in situ comparison of three widely used photo-cross-linkers ⬇️

artículo científico

Antibodies against an inter-domain segment of polypeptide chain inhibit active-site coupling in the pyruvate dehydrogenase multienzyme complex

artículo científico publicado en 1989

Apparent Mutualism Between Verticordia nitens and V-Aurea (Myrtaceae) and Their Oil-Ingesting Bee Pollinators (Hymenoptera, Colletidae)

scholarly article by TF Houston et al published 1993 in Australian Journal of Botany

Assessing the causes and consequences of co-polymerization in amyloid formation ⬇️

artículo científico publicado en 2013

Atomic Details of the Interactions of Glycosaminoglycans with Amyloid-β Fibrils ⬇️

artículo científico publicado en 2016

Author Correction: Fibril structures of diabetes-related amylin variants reveal a basis for surface-templated assembly

artículo científico publicado en 2020

Avoidance of Epimerization in the Synthesis of Peptide Thioesters Using Fmoc Protection

Beta edge strands in protein structure prediction and aggregation.

artículo científico publicado en 2003

Beta(2)-microglobulin and its deamidated variant, N17D form amyloid fibrils with a range of morphologies in vitro

artículo científico publicado en 2001

Characterisation of the conformational properties of urea-unfolded Im7: implications for the early stages of protein folding

artículo científico publicado en 2006

Characterization of Amyloid Oligomers by Electrospray Ionization-Ion Mobility Spectrometry-Mass Spectrometry (ESI-IMS-MS).

artículo científico publicado en 2016

Characterization of the response of primary cells relevant to dialysis-related amyloidosis to β2-microglobulin monomer and fibrils ⬇️

artículo científico publicado en 2011

Co-populated conformational ensembles of beta2-microglobulin uncovered quantitatively by electrospray ionization mass spectrometry ⬇️

artículo científico publicado en 2004

Co-translocational misfolding in the ER of living cells

artículo científico publicado en 2003

Collagen I Weakly Interacts with the β-Sheets of β2-Microglobulin and Enhances Conformational Exchange To Induce Amyloid Formation

artículo científico publicado en 2020

Comparing Hydrogen Deuterium Exchange and Fast Photochemical Oxidation of Proteins: a Structural Characterisation of Wild-Type and ΔN6 β2-Microglobulin ⬇️

artículo científico publicado en 2018

Comparison of the Refolding Hen Lysozyme from Dimethyl Sulfoxide and Guanidinium Chloride

artículo científico publicado en 1995

Comparison of the aggregation of homologous β2-microglobulin variants reveals protein solubility as a key determinant of amyloid formation ⬇️

artículo científico publicado en 2016

Comparison of the transition state ensembles for folding of Im7 and Im9 determined using all-atom molecular dynamics simulations with phi value restraints

artículo científico publicado en 2004

Competing pathways determine fibril morphology in the self-assembly of beta2-microglobulin into amyloid

artículo científico publicado en 2005

Competition between intramolecular and intermolecular interactions in an amyloid-forming protein

artículo científico publicado en 2009

Conformation of GroEL-bound alpha-lactalbumin probed by mass spectrometry

artículo científico publicado en 1994

Conformational Conversion during Amyloid Formation at Atomic Resolution

artículo científico publicado en 2011

Conformational Properties of Four Peptides Spanning the Sequence of Hen Lysozyme

artículo científico publicado en 1995

Conformational dynamics is more important than helical propensity for the folding of the all α-helical protein Im7. ⬇️

artículo científico publicado en 2013

Conformational flexibility and folding of synthetic peptides representing an interdomain segment of polypeptide chain in the pyruvate dehydrogenase multienzyme complex of Escherichia coli

artículo científico publicado en 1989

Conformational flexibility within the nascent polypeptide-associated complex enables its interactions with structurally diverse client proteins ⬇️

artículo científico publicado en 2018

Conformational properties of the unfolded state of Im7 in nondenaturing conditions

artículo científico publicado en 2011

Covalent cross-linking within supramolecular peptide structures

artículo científico publicado en 2012

Crystal structure of monomeric human  -2-microglobulin reveals clues to its amyloidogenic properties ⬇️

artículo científico publicado en 2002

Crystal structure of the mutant D52S hen egg white lysozyme with an oligosaccharide product

artículo científico publicado en 1994

Deciphering drift time measurements from travelling wave ion mobility spectrometry-mass spectrometry studies

artículo científico publicado en 2009

Demonstration by NMR of folding domains in lysozyme

artículo científico publicado en 1991

Desolvation and development of specific hydrophobic core packing during Im7 folding.

artículo científico publicado en 2010

Detailed evaluation of the performance of microfluidic T mixers using fluorescence and ultraviolet resonance Raman spectroscopy

Detection of transient protein folding populations by mass spectrometry

artículo científico publicado en 1993

Determination of an ensemble of structures representing the intermediate state of the bacterial immunity protein Im7.

artículo científico publicado en 2005

Direct observation of oligomeric species formed in the early stages of amyloid fibril formation using electrospray ionisation mass spectrometry

artículo científico publicado en 2006

Direct three-dimensional visualization of membrane disruption by amyloid fibrils

artículo científico publicado en 2012

Dissecting key residues in folding and stability of the bacterial immunity protein 7

artículo científico publicado en 2011

Dissecting the effects of periplasmic chaperones on the in vitro folding of the outer membrane protein PagP ⬇️

artículo científico publicado en 2013

Distinguishing closely related amyloid precursors using an RNA aptamer ⬇️

artículo científico

Distortion of the bilayer and dynamics of the BAM complex in lipid nanodiscs

artículo científico publicado en 2020

Donor-strand exchange in chaperone-assisted pilus assembly proceeds through a concerted beta strand displacement mechanism

artículo científico publicado en 2006

Donor-strand exchange in chaperone-assisted pilus assembly revealed in atomic detail by molecular dynamics ⬇️

artículo científico publicado en 2007

Dual Role of Ribosome-Binding Domain of NAC as a Potent Suppressor of Protein Aggregation and Aging-Related Proteinopathies

scientific article published on 11 April 2019

Dynamic action of the Sec machinery during initiation, protein translocation and termination revealed by single molecule fluorescence

Dynamic action of the Sec machinery during initiation, protein translocation and termination. ⬇️

artículo científico publicado en 2018

Dynamic interplay between the periplasmic chaperone SurA and the BAM complex in outer membrane protein folding

artículo científico publicado en 2022

Dynamics in the unfolded state of beta2-microglobulin studied by NMR.

artículo científico publicado en 2004

ESI-IMS-MS: A method for rapid analysis of protein aggregation and its inhibition by small molecules ⬇️

artículo científico publicado en 2015

Effect of sequence variation on the mechanical response of amyloid fibrils probed by steered molecular dynamics simulation

artículo científico publicado en 2012

Effects of Periplasmic Chaperones and Membrane Thickness on BamA-Catalyzed Outer-Membrane Protein Folding ⬇️

artículo científico publicado en 2017

Effects of hydration on the mechanical response of individual collagen fibrils

article

Elongated oligomers in beta2-microglobulin amyloid assembly revealed by ion mobility spectrometry-mass spectrometry

artículo científico publicado en 2010

Energy landscapes of functional proteins are inherently risky ⬇️

artículo científico publicado en 2014

Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo ⬇️

artículo científico publicado en 2016

Epigallocatechin-3-gallate remodels apolipoprotein A-I amyloid fibrils into soluble oligomers in the presence of heparin ⬇️

artículo científico publicado en 2018

Equilibrium hydrogen exchange reveals extensive hydrogen bonded secondary structure in the on-pathway intermediate of Im7.

artículo científico publicado en 2004

Erratum: Pulling geometry defines the mechanical resistance of a β-sheet protein

artículo científico publicado en 2003

Examination of Ataxin-3 (atx-3) Aggregation by Structural Mass Spectrometry Techniques: A Rationale for Expedited Aggregation upon Polyglutamine (polyQ) Expansion ⬇️

artículo científico publicado en 2015

Expanding the repertoire of amyloid polymorphs by co-polymerization of related protein precursors

artículo científico publicado en 2013

Extracellular matrix components modulate different stages in β2-microglobulin amyloid formation.

artículo científico publicado en 2019

Extraction of accurate biomolecular parameters from single-molecule force spectroscopy experiments ⬇️

artículo científico publicado en 2015

FPOP-LC-MS/MS Suggests Differences in Interaction Sites of Amphipols and Detergents with Outer Membrane Proteins ⬇️

artículo científico publicado en 2016

Far-UV Circular Dichroism Reveals a Conformational Switch in a Peptide Fragment from the .beta.-Sheet of Hen Lysozyme

artículo científico publicado en 1994

Fast and slow tracks in lysozyme folding: insight into the role of domains in the folding process

artículo científico publicado en 1997

Fibril fragmentation enhances amyloid cytotoxicity

artículo científico publicado en 2009

Fibril fragmentation in amyloid assembly and cytotoxicity: when size matters

artículo científico publicado en 2010

Fibril growth kinetics reveal a region of beta2-microglobulin important for nucleation and elongation of aggregation

artículo científico publicado en 2008

Fibril structures of diabetes-related amylin variants reveal a basis for surface-templated assembly

scientific article published on 14 September 2020

Folding versus aggregation: polypeptide conformations on competing pathways

artículo científico publicado en 2007

Force mode atomic force microscopy as a tool for protein folding studies

Force-induced remodelling of proteins and their complexes ⬇️

artículo científico publicado en 2015

From computer simulations to human disease: emerging themes in protein folding

artículo científico publicado en 1999

Glimpses of the molecular mechanisms of beta2-microglobulin fibril formation in vitro: aggregation on a complex energy landscape

artículo científico publicado en 2009

Globular tetramers of beta(2)-microglobulin assemble into elaborate amyloid fibrils

scientific article published on 05 April 2009

GroEL accelerates the refolding of hen lysozyme without changing its folding mechanism.

artículo científico publicado en 1999

GroEL: More than Just a folding cage

artículo científico publicado en 2006

HDX-ESI-MS reveals enhanced conformational dynamics of the amyloidogenic protein beta(2)-microglobulin upon release from the MHC-1.

artículo científico publicado en 2008

Helix stability and hydrophobicity in the folding mechanism of the bacterial immunity protein Im9.

artículo científico publicado en 2005

Hen egg white lysozyme expressed in, and secreted from, Aspergillus niger is correctly processed and folded

artículo científico publicado en 1990

Hierarchical assembly of beta2-microglobulin amyloid in vitro revealed by atomic force microscopy

artículo científico publicado en 2003

Homage to Chris Dobson

artículo científico publicado en 2019

How TriC folds tricky proteins

artículo científico publicado en 2014

Hydrogen exchange in native and denatured states of hen egg-white lysozyme

artículo científico publicado en 1992

Hydrogen exchange properties of proteins in native and denatured states monitored by mass spectrometry and NMR.

artículo científico publicado en 1997

Identification of a mechanical rheostat in the hydrophobic core of protein L.

artículo científico publicado en 2009

Identification of a novel site of interaction between ataxin-3 and the amyloid aggregation inhibitor polyglutamine binding peptide 1. ⬇️

artículo científico publicado en 2017

Identification of the N-terminal peptide binding site of glucose-regulated protein 94.

artículo científico publicado en 2004

Im7 folding mechanism: misfolding on a path to the native state

artículo científico publicado en 2002

Inducing protein aggregation by extensional flow ⬇️

artículo científico publicado en 2017

Insights into Protein Folding Using Physical Techniques: Studies of Lysozyme and $\alpha $ -lactalbumin

artículo científico publicado en 1995

Insights into the consequences of co-polymerisation in the early stages of IAPP and Aβ peptide assembly from mass spectrometry ⬇️

artículo científico publicado en 2015

Insights into the role of the beta-2 microglobulin D-strand in amyloid propensity revealed by mass spectrometry ⬇️

artículo científico publicado en 2013

Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis

artículo científico publicado en 1997

Inter-domain dynamics in the chaperone SurA and multi-site binding to its outer membrane protein clients

artículo científico publicado en 2020

Intermediates: ubiquitous species on folding energy landscapes?

artículo científico publicado en 2007

Intermolecular alignment in β2-microglobulin amyloid fibrils

artículo científico publicado en 2010

Internal friction of single polypeptide chains at high stretch

artículo científico publicado en 2008

Investigating the Structural Compaction of Biomolecules Upon Transition to the Gas-Phase Using ESI-TWIMS-MS. ⬇️

artículo científico publicado en 2017

Investigating the structural properties of amyloid-like fibrils formed in vitro from beta2-microglobulin using limited proteolysis and electrospray ionisation mass spectrometry

artículo científico publicado en 2006

Investigation into the role of macrophages in the formation and degradation of beta2-microglobulin amyloid fibrils

artículo científico publicado en 2007

Investigation of protein folding by mass spectrometry.

artículo científico publicado en 1996

Investigation of the mechanism of active site coupling in the pyruvate dehydrogenase multienzyme complex of Escherichia coli by protein engineering

artículo científico publicado en 1988

Ion mobility spectrometry-mass spectrometry defines the oligomeric intermediates in amylin amyloid formation and the mode of action of inhibitors ⬇️

artículo científico publicado en 2013

Kinetic Consequences of the Removal of a Disulfide Bridge on the Folding of Hen Lysozyme

artículo científico publicado en 1994

Kinetic studies of beta-sheet protein folding

artículo científico publicado en 1998

Lateral opening in the intact β-barrel assembly machinery captured by cryo-EM. ⬇️

artículo científico publicado en 2016

Leaf Demography, Sclerophylly and Ecophysiology of Two Banksias With Contrasting Leaf Life Spans

artículo científico publicado en 1992

Ligand binding to distinct states diverts aggregation of an amyloid-forming protein ⬇️

artículo científico

Long-Range Conformational Changes in Monoclonal Antibodies Revealed Using FPOP-LC-MS/MS

scientific article published on 13 November 2019

Looking Beyond the Core: The Role of Flanking Regions in the Aggregation of Amyloidogenic Peptides and Proteins

artículo científico publicado en 2020

Macromolecular crowding enhances the detection of DNA and proteins by a solid-state nanopore

artículo científico publicado en 2020

Magic angle spinning NMR analysis of beta2-microglobulin amyloid fibrils in two distinct morphologies

artículo científico publicado en 2010

Malleability of the folding mechanism of the outer membrane protein PagP: parallel pathways and the effect of membrane elasticity

artículo científico publicado en 2012

Mass spectrometric methods to analyze the structural organization of macromolecular complexes

artículo científico

Mass spectrometry-enabled structural biology of membrane proteins ⬇️

artículo científico publicado en 2018

Mechanical resistance of proteins explained using simple molecular models

artículo científico publicado en 2005

Mechanically unfolding proteins: the effect of unfolding history and the supramolecular scaffold

artículo científico publicado en 2002

Mechanically unfolding the small, topologically simple protein L.

artículo científico publicado en 2005

Mechanisms of amyloid formation revealed by solution NMR ⬇️

artículo científico publicado en 2015

Mechanistic studies of the biogenesis and folding of outer membrane proteins in vitro and in vivo: what have we learned to date? ⬇️

artículo científico publicado en 2014

Microsecond folding dynamics of the F13W G29A mutant of the B domain of staphylococcal protein A by laser-induced temperature jump ⬇️

artículo científico publicado en 2004

Modulation of Amyloidogenic Protein Self-Assembly Using Tethered Small Molecules

artículo científico publicado en 2020

Modulation of β-Amyloid Fibril Formation in Alzheimer's Disease by Microglia and Infection

scientific article published on 26 November 2020

Molecular Origins of the Compatibility between Glycosaminoglycans and Aβ40 Amyloid Fibrils ⬇️

artículo científico publicado en 2017

Molecular dynamics simulations of mechanical failure in polymorphic arrangements of amyloid fibrils containing structural defects ⬇️

artículo científico publicado en 2013

Molecular insights into the surface-catalyzed secondary nucleation of amyloid-β40 (Aβ40) by the peptide fragment Aβ16–22.

artículo científico publicado en 2019

Monitoring copopulated conformational states during protein folding events using electrospray ionization-ion mobility spectrometry-mass spectrometry

artículo científico publicado en 2007

Monitoring oligomer formation from self-aggregating amylin peptides using ESI-IMS-MS

MpUL-multi: Software for Calculation of Amyloid Fibril Mass per Unit Length from TB-TEM Images ⬇️

artículo científico

Mutational analysis of the ability of resveratrol to inhibit amyloid formation by islet amyloid polypeptide: critical evaluation of the importance of aromatic-inhibitor and histidine-inhibitor interactions

artículo científico publicado en 2015

N-terminal acetylation of α-synuclein induces increased transient helical propensity and decreased aggregation rates in the intrinsically disordered monomer

artículo científico publicado en 2012

NMR analysis of the conformational properties of the trapped on-pathway folding intermediate of the bacterial immunity protein Im7.

artículo científico publicado en 2006

Native-like secondary structure in a peptide from the α-domain of hen lysozyme

artículo científico publicado en 1996

Nucleation of protein fibrillation by nanoparticles

artículo científico publicado en 2007

Optimizing protein stability in vivo

artículo científico publicado en 2009

Orientation of a Diagnostic Ligand Bound to Macroscopically-Aligned Amyloid-β Fibrils Determined by Solid-state NMR

article by David Townsend et al published 24 October 2018 in Journal of Physical Chemistry Letters

Outer membrane protein folding from an energy landscape perspective ⬇️

artículo científico publicado en 2017

Partially unfolded species populated during equilibrium denaturation of the beta-sheet protein Y74W apo-pseudoazurin

artículo científico publicado en 2000

Partially unfolded states of beta(2)-microglobulin and amyloid formation in vitro

artículo científico publicado en 2000

Perturbing the folding energy landscape of the bacterial immunity protein Im7 by site-specific N-linked glycosylation

artículo científico publicado en 2010

Phosphorylation as a tool to modulate aggregation propensity and to predict fibril architecture

artículo científico publicado en 2011

Physicochemical characterization of the cytoplasmic domain of the epidermal growth factor receptor and evidence for conformational changes associated with its activation by ammonium sulphate

artículo científico publicado en 1995

Potential human transmission of amyloid β pathology: surveillance and risks

scientific article published on 16 September 2020

Probing dynamics within amyloid fibrils using a novel capping method

artículo científico publicado en 2009

Production and Characterization of RNA Aptamers Specific for Amyloid Fibril Epitopes

artículo científico publicado en 2007

Progressive glycosylation of albumin and its effect on the binding of homocysteine may be a key step in the pathogenesis of vascular damage in diabetes mellitus

artículo científico publicado en 2007

Protein folding and binding: from biology to physics and back again

artículo científico publicado en 2010

Protein folding mechanisms: new methods and emerging ideas

artículo científico publicado en 2000

Protein folding: defining a "standard" set of experimental conditions and a preliminary kinetic data set of two-state proteins

artículo científico publicado en 2005

Protein folding: progress made and promises ahead

artículo científico publicado en 2000

Protein folding: pulling back the frontiers

artículo científico publicado en 2000

Pseudospecific docking surfaces on electron transfer proteins as illustrated by pseudoazurin, cytochrome c550 and cytochrome cd1 nitrite reductase

artículo científico publicado en 1995

Pulling geometry defines the mechanical resistance of a beta-sheet protein

artículo científico publicado en 2003

PyXlinkViewer: a flexible tool for visualisation of protein chemical crosslinking data within the PyMOL molecular graphics system

scientific article published on 18 June 2020

Quantifying heterogeneity and conformational dynamics from single molecule FRET of diffusing molecules: recurrence analysis of single particles (RASP).

artículo científico publicado en 2011

Rapid Mapping of Protein Interactions Using Tag-Transfer Photocrosslinkers ⬇️

artículo científico publicado en 2018

Rapid Mapping of Protein Interactions Using Tag‐Transfer Photocrosslinkers

Rapid folding with and without populated intermediates in the homologous four-helix proteins Im7 and Im9.

artículo científico publicado en 1999

Responsive gels formed by the spontaneous self-assembly of peptides into polymeric beta-sheet tapes

artículo científico publicado en 1997

Ribosome-mediated folding of partially unfolded ricin A-chain.

artículo científico publicado en 2000

Richard Nelson Perham. 27 April 1937—14 February 2015 ⬇️

Role of the N and C-terminal strands of beta 2-microglobulin in amyloid formation at neutral pH.

artículo científico publicado en 2003

Role of the lipid bilayer in outer membrane protein folding in Gram negative bacteria

scientific article published on 04 June 2020

Role of the single disulphide bond of beta(2)-microglobulin in amyloidosis in vitro

artículo científico publicado en 2001

Screening and classifying small-molecule inhibitors of amyloid formation using ion mobility spectrometry-mass spectrometry ⬇️

artículo científico publicado en 2014

Second order rate constants of donor-strand exchange reveal individual amino acid residues important in determining the subunit specificity of pilus biogenesis ⬇️

artículo científico publicado en 2011

Secondary structure in the core of amyloid fibrils formed from human β₂m and its truncated variant ΔN6. ⬇️

artículo científico publicado en 2014

Segmental structure and protein domains in the pyruvate dehydrogenase multienzyme complex of Escherichia coli. Genetic reconstruction in vitro and 1H-n.m.r. spectroscopy

artículo científico publicado en 1987

Semisynthesis of a glycosylated Im7 analogue for protein folding studies

artículo científico publicado en 2005

Separation of beta2-microglobulin conformers by high-field asymmetric waveform ion mobility spectrometry (FAIMS) coupled to electrospray ionisation mass spectrometry

artículo científico publicado en 2004

Single-molecule studies of the Im7 folding landscape

artículo científico publicado en 2010

Site-directed mutagenesis and 1H NMR spectroscopy of an interdomain segment in the pyruvate dehydrogenase multienzyme complex of Escherichia coli

artículo científico publicado en 1988

Site-specific identification of an aβ fibril-heparin interaction site by using solid-state NMR spectroscopy

artículo científico publicado en 2012

Skp is a multivalent chaperone of outer-membrane proteins ⬇️

artículo científico publicado en 2016

Small molecule probes of protein aggregation ⬇️

artículo científico publicado en 2017

Special Issue: The Molecular and Cellular Mechanisms of Amyloidosis

artículo científico publicado en 2012

Specific glycosaminoglycans promote unseeded amyloid formation from beta2-microglobulin under physiological conditions.

artículo científico publicado en 2007

Spot the Difference: Function versus Toxicity in Amyloid Fibrils

scientific article published on 03 May 2020

Stacked sets of parallel, in-register beta-strands of beta2-microglobulin in amyloid fibrils revealed by site-directed spin labeling and chemical labeling

artículo científico publicado en 2010

Structural analysis of the rate-limiting transition states in the folding of Im7 and Im9: similarities and differences in the folding of homologous proteins

artículo científico publicado en 2003

Structural and mechanistic basis of immunity toward endonuclease colicins

artículo científico publicado en 1999

Structural and mechanistic consequences of polypeptide binding by GroEL.

artículo científico publicado en 1997

Structural determinants of polymerization reactivity of the P pilus adaptor subunit PapF

artículo científico publicado en 2008

Structural insight into the formation of lipoprotein-β-barrel complexes

artículo científico publicado en 2020

Structural insights into the polymorphism of amyloid-like fibrils formed by region 20-29 of amylin revealed by solid-state NMR and X-ray fiber diffraction

artículo científico publicado en 2008

Structural mapping of oligomeric intermediates in an amyloid assembly pathway

scientific article published on 25 September 2019

Structural plasticity and noncovalent substrate binding in the GroEL apical domain. A study using electrospay ionization mass spectrometry and fluorescence binding studies ⬇️

artículo científico publicado en 2002

Structural properties of an amyloid precursor of beta(2)-microglobulin

artículo científico publicado en 2002

Structure and dynamics of oligomeric intermediates in β2-microglobulin self-assembly

artículo científico

Substrate protein folds while it is bound to the ATP-independent chaperone Spy ⬇️

artículo científico publicado en 2015

Sulfate-induced effects in the on-pathway intermediate of the bacterial immunity protein Im7.

artículo científico publicado en 2006

Switching two-state to three-state kinetics in the helical protein Im9 via the optimisation of stabilising non-native interactions by design

artículo científico publicado en 2004

Synthesis, characterization and applications of a perdeuterated amphipol

artículo científico publicado en 2014

Systematic Examination of Polymorphism in Amyloid Fibrils by Molecular-Dynamics Simulation ⬇️

artículo científico publicado el 4 de mayo de 2011

Systematic analysis of nucleation-dependent polymerization reveals new insights into the mechanism of amyloid self-assembly

artículo científico publicado en 2008

Systematic analysis of the use of amphipathic polymers for studies of outer membrane proteins using mass spectrometry ⬇️

artículo científico publicado en 2015

Tertiary interactions in the folding pathway of hen lysozyme: kinetic studies using fluorescent probes.

artículo científico publicado en 1994

The Greek key protein apo-pseudoazurin folds through an obligate on-pathway intermediate

artículo científico publicado en 1999

The N-terminal helix is a post-assembly clamp in the bacterial outer membrane protein PagP.

artículo científico publicado en 2007

The Organization of Aromatic Side Groups in an Amyloid Fibril Probed by Solid-State2H and19F NMR Spectroscopy

artículo científico publicado en 2006

The Refolding of Human Lysozyme: A Comparison with the Structurally Homologous Hen Lysozyme

artículo científico publicado en 1994

The Role of SurA PPIase Domains in Preventing Aggregation of the Outer-Membrane Proteins tOmpA and OmpT

artículo científico publicado en 2019

The Yin and Yang of protein folding

artículo científico publicado en 2005

The complete amino acid sequence confirms the presence of pseudoazurin in Thiosphaera pantotropha.

artículo científico publicado en 1995

The effect of core destabilization on the mechanical resistance of I27.

artículo científico publicado en 2002

The effect of increasing the stability of non-native interactions on the folding landscape of the bacterial immunity protein Im9.

artículo científico publicado en 2007

The effect of protein complexation on the mechanical stability of Im9.

artículo científico publicado en 2007

The folding of hen lysozyme involves partially structured intermediates and multiple pathways

artículo científico publicado en 1992

The making of a nutrition professional: the Association for Nutrition register

artículo científico publicado en 2012

The mechanism of folding of Im7 reveals competition between functional and kinetic evolutionary constraints

artículo científico publicado en 2009

The oligomeric state and arrangement of the active bacterial translocon

artículo científico publicado en 2010

The origin of the alpha-domain intermediate in the folding of hen lysozyme

artículo científico publicado en 1998

The pseudoazurin gene from Thiosphaera pantotropha: analysis of upstream putative regulatory sequences and overexpression in Escherichia coli

artículo científico

The role of barrels 1 and 2 in the enzymatic activity of factor XIII-A. ⬇️

artículo científico publicado en 2018

The role of chaperone-subunit usher domain interactions in the mechanism of bacterial pilus biogenesis revealed by ESI-MS.

artículo científico publicado en 2012

The role of conformational flexibility in β2-microglobulin amyloid fibril formation at neutral pH. ⬇️

artículo científico publicado en 2012

The role of high-dimensional diffusive search, stabilization, and frustration in protein folding ⬇️

artículo científico publicado en 2014

The role of the IT-state in D76N β2-microglobulin amyloid assembly: a crucial intermediate or an innocuous bystander?

artículo científico publicado en 2020

The structure and dynamics in solution of Cu(I) pseudoazurin from Paracoccus pantotrophus

artículo científico publicado en 2000

The structure of a β2-microglobulin fibril suggests a molecular basis for its amyloid polymorphism

scientific article published in Nature Communications

The transition state for folding of an outer membrane protein

artículo científico publicado en 2010

The yeast prion Ure2p retains its native alpha-helical conformation upon assembly into protein fibrils in vitro

artículo científico publicado en 2002

Thermal unfolding of an intermediate is associated with non-arrhenius kinetics in the folding of hen lysozyme

artículo científico publicado en 2000

Thermodynamic consequences of the removal of a disulphide bridge from hen lysozyme

artículo científico publicado en 1992

Thermodynamic description of polymorphism in Q- and N-rich peptide aggregates revealed by atomistic simulation

artículo científico publicado en 2009

Thermodynamic phase diagram of amyloid-β (16-22) peptide

article published in the Proceedings of the National Academy of Sciences of the United States of America

Topological Dissection of the Membrane Transport Protein Mhp1 Derived from Cysteine Accessibility and Mass Spectrometry ⬇️

artículo científico publicado en 2017

Towards an understanding of the structural molecular mechanism of beta(2)-microglobulin amyloid formation in vitro

artículo científico publicado en 2005

Trapping the on-pathway folding intermediate of Im7 at equilibrium.

artículo científico publicado en 2004

Trifluoromethyldiazirine: an effective photo-induced cross-linking probe for exploring amyloid formation

artículo científico publicado en 2008

Tuning the elastic modulus of hydrated collagen fibrils

artículo científico publicado en 2009

Two-way communication between SecY and SecA suggests a Brownian ratchet mechanism for protein translocation ⬇️

artículo científico publicado en 2016

Ultrarapid mixing experiments reveal that Im7 folds via an on-pathway intermediate

artículo científico publicado en 2001

Ultraviolet resonance Raman studies reveal the environment of tryptophan and tyrosine residues in the native and partially folded states of the E colicin-binding immunity protein Im7.

artículo científico publicado en 2005

Understanding co-polymerization in amyloid formation by direct observation of mixed oligomers ⬇️

artículo científico publicado en 2017

Understanding how proteins fold: the lysozyme story so far.

artículo científico publicado en 1994

Understanding the complex mechanisms of β2-microglobulin amyloid assembly

scientific article published on 13 June 2011

Unfolding dynamics of proteins under applied force ⬇️

artículo científico publicado en 2003

Unraveling the molecular basis of subunit specificity in P pilus assembly by mass spectrometry ⬇️

artículo científico publicado en 2008

Urea-induced unfolding of the immunity protein Im9 monitored by spFRET.

artículo científico publicado en 2006

Using chimeric immunity proteins to explore the energy landscape for alpha-helical protein folding

artículo científico publicado en 2001

Using extensional flow to reveal diverse aggregation landscapes for three IgG1 molecules ⬇️

artículo científico publicado en 2018

Using hydroxyl radical footprinting to explore the free energy landscape of protein folding. ⬇️

artículo científico publicado en 2015

Using protein engineering to understand and modulate aggregation

artículo científico publicado en 2020

Viscoelastic measurements of single molecules on a millisecond time scale by magnetically driven oscillation of an atomic force microscope cantilever

artículo científico publicado en 2005

Viscoelastic properties of single polysaccharide molecules determined by analysis of thermally driven oscillations of an atomic force microscope cantilever

artículo científico publicado en 2004

Viscoelastic study of the mechanical unfolding of a protein by AFM.

artículo científico publicado en 2006

Visualization of transient protein-protein interactions that promote or inhibit amyloid assembly ⬇️

artículo científico publicado en 2014

Visualizing and trapping transient oligomers in amyloid assembly pathways

artículo científico publicado en 2020

Weighing the evidence for structure: electrospray ionization mass spectrometry of proteins

artículo científico publicado en 1995

What's new in protein folding? EMBO Workshop: Protein folding and misfolding inside and outside the cell ⬇️

artículo científico publicado el 1 de enero de 1998

[24] Probing conformations of GroEL-bound substrate proteins by mass spectrometry

artículo científico publicado en 1998

pH as a trigger of peptide beta-sheet self-assembly and reversible switching between nematic and isotropic phases

artículo científico publicado en 2003

pH-induced molecular shedding drives the formation of amyloid fibril-derived oligomers ⬇️

artículo científico publicado en 2015

β2-Microglobulin amyloid fibril-induced membrane disruption is enhanced by endosomal lipids and acidic pH ⬇️

artículo científico publicado en 2014

β2-microglobulin amyloid fibrils are nanoparticles that disrupt lysosomal membrane protein trafficking and inhibit protein degradation by lysosomes ⬇️

artículo científico publicado en 2014

Dominio Público Uruguay está sostenido por:

Acerca de Dominio Público Uruguay

Ayuda