Lista de obras - Marnie Blewitt - Dominio Público Uruguay

A comparison of control samples for ChIP-seq of histone modifications

artículo científico publicado en 2014

A genome-wide screen for modifiers of transgene variegation identifies genes with critical roles in development

artículo científico publicado en 2008

An ENU mutagenesis screen identifies novel and known genes involved in epigenetic processes in the mouse

artículo científico publicado en 2013

An N-ethyl-N-nitrosourea screen for genes involved in variegation in the mouse

artículo científico publicado en 2005

An in vivo model for analysis of developmental erythropoiesis and globin gene regulation

artículo científico publicado en 2014

Analysis of Histone Modifications in Acute Myeloid Leukaemia Using Chromatin Immunoprecipitation.

artículo científico publicado en 2018

BAF complex-mediated chromatin relaxation is required for establishment of X chromosome inactivation

artículo científico publicado en 2022

ChIP-seq analysis reveals distinct H3K27me3 profiles that correlate with transcriptional activity

artículo científico publicado en 2011

Comprehensive characterization of distinct states of human naive pluripotency generated by reprogramming

artículo científico publicado en 2017

Crystal structure of the hinge domain of Smchd1 reveals its dimerization mode and nucleic acid-binding residues

artículo científico publicado en 2020

De novo mutations in SMCHD1 cause Bosma arhinia microphthalmia syndrome and abrogate nasal development

artículo científico publicado en 2017

Development of a KDM6b shRNA conditional knock down mouse model

article

Dynamic reprogramming of DNA methylation at an epigenetically sensitive allele in mice

artículo científico publicado en 2006

Epigenetic regulator Smchd1 functions as a tumor suppressor

artículo científico publicado en 2012

FSHD2- and BAMS-associated mutations confer opposing effects on SMCHD1 function

artículo científico publicado en 2018

Function of PRC2 accessory factors in haematopoietic stem cells

Functional interdependence of BRD4 and DOT1L in MLL leukemia

artículo científico publicado en 2016

Genome-wide DNA methylation analysis identifies hypomethylated genes regulated by FOXP3 in human regulatory T cells

artículo científico publicado en 2013

Genome-wide binding and mechanistic analyses of Smchd1-mediated epigenetic regulation

artículo científico publicado en 2015

Germline loss ofMBD4predisposes to leukaemia due to a mutagenic cascade driven by 5mC

Glimma: interactive graphics for gene expression analysis

artículo científico publicado en 2017

HBO1 is required for the maintenance of leukaemia stem cells

scientific article published on 11 December 2019

High concordance between Illumina HiSeq2500 and NextSeq500 for reduced representation bisulfite sequencing (RRBS).

artículo científico publicado en 2016

Hippocampal neurogenesis mediates sex-specific effects of social isolation and exercise on fear extinction in adolescence

artículo científico publicado en 2021

How the mouse got its spots

artículo científico publicado en 2004

Ihstone H3 lysine 9 methylation is involved not only in maintaining epigenetic silencing, but is essential for setting up gene silencing

article

Jarid2 regulates hematopoietic stem cell function by acting with polycomb repressive complex 2.

artículo científico publicado en 2015

Long-range chromatin interactions on the inactive X and at Hox clusters are regulated by the non-canonical SMC protein Smchd1

Loss of p53 Causes Stochastic Aberrant X-Chromosome Inactivation and Female-Specific Neural Tube Defects

scientific article published on 01 April 2019

MBD4 guards against methylation damage and germ line deficiency predisposes to clonal hematopoiesis and early-onset AML

artículo científico publicado en 2018

Metastable epialleles in mammals

artículo científico publicado en 2002

Modifiers of epigenetic reprogramming show paternal effects in the mouse.

artículo científico publicado en 2007

Opposing roles of polycomb repressive complexes in hematopoietic stem and progenitor cells

artículo científico publicado en 2010

Polycomb repressive complex 2 (PRC2) restricts hematopoietic stem cell activity

artículo científico publicado en 2008

Polycomb repressive complex 2 (PRC2) suppresses Eμ-myc lymphoma.

artículo científico publicado en 2013

Polycomb repressive complex 2 component Suz12 is required for hematopoietic stem cell function and lymphopoiesis

artículo científico publicado en 2015

RNF41 regulates the damage recognition receptor Clec9A and antigen cross-presentation in mouse dendritic cells

artículo científico publicado en 2020

Reduced dosage of the modifiers of epigenetic reprogramming Dnmt1, Dnmt3L, SmcHD1 and Foxo3a has no detectable effect on mouse telomere length in vivo

artículo científico publicado en 2011

Relating SMCHD1 structure to its function in epigenetic silencing

artículo científico publicado en 2020

Repression of Igf1 expression by Ezh2 prevents basal cell differentiation in the developing lung

artículo científico publicado en 2015

Role of SmcHD1 in establishment of epigenetic states required for the maintenance of the X-inactivated state in mice

scholarly article by Yuki Sakakibara published in August 2018

SMCHD1 is involved in de novo methylation of the DUX4-encoding D4Z4 macrosatellite

scientific article published on 01 April 2019

Setdb1-mediated H3K9 methylation is enriched on the inactive X and plays a role in its epigenetic silencing

artículo científico publicado en 2016

SmcHD1, containing a structural-maintenance-of-chromosomes hinge domain, has a critical role in X inactivation

scientific journal article

Smchd1 Targeting to the Inactive X Is Dependent on the Xist-HnrnpK-PRC1 Pathway

artículo científico publicado en 2018

Smchd1 haploinsufficiency exacerbates the phenotype of a transgenic FSHD1 mouse model

artículo científico publicado en 2017

Smchd1 is a maternal effect gene required for genomic imprinting

artículo científico publicado en 2020

Smchd1 regulates a subset of autosomal genes subject to monoallelic expression in addition to being critical for X inactivation

artículo científico publicado en 2013

Smchd1 regulates long-range chromatin interactions on the inactive X chromosome and at Hox clusters

artículo científico publicado en 2018

Studying X chromosome inactivation in the single-cell genomic era

scientific article published on 20 April 2018

TLR regulation of SPSB1 controls inducible nitric oxide synthase induction.

artículo científico publicado en 2011

The Epigenetic Regulator SMCHD1 in Development and Disease

artículo científico publicado en 2017

The epigenetic regulator Smchd1 contains a functional GHKL-type ATPase domain.

artículo científico publicado en 2016

The first mouse mutants of D14Abb1e (Fam208a) show that it is critical for early development.

artículo científico publicado en 2014

The hinge domain of the epigenetic repressor Smchd1 adopts an unconventional homodimeric configuration

artículo científico publicado en 2016

The polycomb repressive complex 2 governs life and death of peripheral T cells

scientific article published on 20 June 2014

The use of mouse models to study epigenetics

artículo científico publicado en 2013

Transcriptional profiling of the epigenetic regulator Smchd1.

artículo científico publicado en 2015

Transcriptional regulators Myb and BCL11A interplay with DNA methyltransferase 1 in developmental silencing of embryonic and fetal β-like globin genes.

artículo científico publicado en 2013

Unique properties of a subset of human pluripotent stem cells with high capacity for self-renewal

artículo científico publicado en 2020

Using long-read sequencing to detect imprinted DNA methylation

artículo científico publicado en 2019

Why weight? Modelling sample and observational level variability improves power in RNA-seq analyses

artículo científico publicado en 2015

edgeR: a versatile tool for the analysis of shRNA-seq and CRISPR-Cas9 genetic screens

artículo científico publicado en 2014

Lista de obras de Marnie Blewitt

A comparison of control samples for ChIP-seq of histone modifications

A genome-wide screen for modifiers of transgene variegation identifies genes with critical roles in development

An ENU mutagenesis screen identifies novel and known genes involved in epigenetic processes in the mouse

An N-ethyl-N-nitrosourea screen for genes involved in variegation in the mouse

An in vivo model for analysis of developmental erythropoiesis and globin gene regulation

Analysis of Histone Modifications in Acute Myeloid Leukaemia Using Chromatin Immunoprecipitation.

BAF complex-mediated chromatin relaxation is required for establishment of X chromosome inactivation

ChIP-seq analysis reveals distinct H3K27me3 profiles that correlate with transcriptional activity

Comprehensive characterization of distinct states of human naive pluripotency generated by reprogramming

Crystal structure of the hinge domain of Smchd1 reveals its dimerization mode and nucleic acid-binding residues

De novo mutations in SMCHD1 cause Bosma arhinia microphthalmia syndrome and abrogate nasal development

Development of a KDM6b shRNA conditional knock down mouse model

Dynamic reprogramming of DNA methylation at an epigenetically sensitive allele in mice

Epigenetic regulator Smchd1 functions as a tumor suppressor

FSHD2- and BAMS-associated mutations confer opposing effects on SMCHD1 function

Function of PRC2 accessory factors in haematopoietic stem cells

Functional interdependence of BRD4 and DOT1L in MLL leukemia

Genome-wide DNA methylation analysis identifies hypomethylated genes regulated by FOXP3 in human regulatory T cells

Genome-wide binding and mechanistic analyses of Smchd1-mediated epigenetic regulation

Germline loss ofMBD4predisposes to leukaemia due to a mutagenic cascade driven by 5mC

Glimma: interactive graphics for gene expression analysis

HBO1 is required for the maintenance of leukaemia stem cells

High concordance between Illumina HiSeq2500 and NextSeq500 for reduced representation bisulfite sequencing (RRBS).

Hippocampal neurogenesis mediates sex-specific effects of social isolation and exercise on fear extinction in adolescence

How the mouse got its spots

Ihstone H3 lysine 9 methylation is involved not only in maintaining epigenetic silencing, but is essential for setting up gene silencing

Jarid2 regulates hematopoietic stem cell function by acting with polycomb repressive complex 2.

Long-range chromatin interactions on the inactive X and at Hox clusters are regulated by the non-canonical SMC protein Smchd1

Loss of p53 Causes Stochastic Aberrant X-Chromosome Inactivation and Female-Specific Neural Tube Defects

MBD4 guards against methylation damage and germ line deficiency predisposes to clonal hematopoiesis and early-onset AML

Metastable epialleles in mammals

Modifiers of epigenetic reprogramming show paternal effects in the mouse.

Opposing roles of polycomb repressive complexes in hematopoietic stem and progenitor cells

Polycomb repressive complex 2 (PRC2) restricts hematopoietic stem cell activity

Polycomb repressive complex 2 (PRC2) suppresses Eμ-myc lymphoma.

Polycomb repressive complex 2 component Suz12 is required for hematopoietic stem cell function and lymphopoiesis

RNF41 regulates the damage recognition receptor Clec9A and antigen cross-presentation in mouse dendritic cells

Reduced dosage of the modifiers of epigenetic reprogramming Dnmt1, Dnmt3L, SmcHD1 and Foxo3a has no detectable effect on mouse telomere length in vivo

Relating SMCHD1 structure to its function in epigenetic silencing

Repression of Igf1 expression by Ezh2 prevents basal cell differentiation in the developing lung

Role of SmcHD1 in establishment of epigenetic states required for the maintenance of the X-inactivated state in mice

SMCHD1 is involved in de novo methylation of the DUX4-encoding D4Z4 macrosatellite

Setdb1-mediated H3K9 methylation is enriched on the inactive X and plays a role in its epigenetic silencing

SmcHD1, containing a structural-maintenance-of-chromosomes hinge domain, has a critical role in X inactivation

Smchd1 Targeting to the Inactive X Is Dependent on the Xist-HnrnpK-PRC1 Pathway

Smchd1 haploinsufficiency exacerbates the phenotype of a transgenic FSHD1 mouse model

Smchd1 is a maternal effect gene required for genomic imprinting

Smchd1 regulates a subset of autosomal genes subject to monoallelic expression in addition to being critical for X inactivation

Smchd1 regulates long-range chromatin interactions on the inactive X chromosome and at Hox clusters

Studying X chromosome inactivation in the single-cell genomic era

TLR regulation of SPSB1 controls inducible nitric oxide synthase induction.

The Epigenetic Regulator SMCHD1 in Development and Disease

The epigenetic regulator Smchd1 contains a functional GHKL-type ATPase domain.

The first mouse mutants of D14Abb1e (Fam208a) show that it is critical for early development.

The hinge domain of the epigenetic repressor Smchd1 adopts an unconventional homodimeric configuration

The polycomb repressive complex 2 governs life and death of peripheral T cells

The use of mouse models to study epigenetics

Transcriptional profiling of the epigenetic regulator Smchd1.

Transcriptional regulators Myb and BCL11A interplay with DNA methyltransferase 1 in developmental silencing of embryonic and fetal β-like globin genes.

Unique properties of a subset of human pluripotent stem cells with high capacity for self-renewal

Using long-read sequencing to detect imprinted DNA methylation

Why weight? Modelling sample and observational level variability improves power in RNA-seq analyses

edgeR: a versatile tool for the analysis of shRNA-seq and CRISPR-Cas9 genetic screens