Lista de obras - Susan Band Horwitz - Dominio Público Uruguay

2-(m-Azidobenzoyl)taxol binds differentially to distinct β-tubulin isotypes

artículo científico publicado en 2016

A Conversation with Susan Band Horwitz

artículo científico publicado en 2015

A Symposium in Honor of Richard G. Powell, a Long-Time Associate Editor of the Journal of Natural Products

artículo científico publicado en 2015

A highly epothilone B-resistant A549 cell line with mutations in tubulin that confer drug dependence

artículo científico publicado en 2005

A label‐free mass spectrometry method for relative quantitation of β‐tubulin isotype expression in human tumor tissue ⬇️

artículo científico publicado el 1 de octubre de 2012

A photoaffinity analogue of discodermolide specifically labels a peptide in beta-tubulin

artículo científico publicado en 2006

Activation of the steroid and xenobiotic receptor (human pregnane X receptor) by nontaxane microtubule-stabilizing agents

artículo científico publicado en 2005

Analysis of tubulin isotypes and mutations from taxol-resistant cells by combined isoelectrofocusing and mass spectrometry

artículo científico publicado en 2003

Characterization of a human βV‐tubulin antibody and expression of this isotype in normal and malignant human tissue ⬇️

artículo científico publicado el 2 de julio de 2012

Correction: Exploiting MEK Inhibitor-Mediated Activation of ERα for Therapeutic Intervention in ER-Positive Ovarian Carcinoma

artículo científico publicado en 2016

Design and Synthesis of (+)-Discodermolide–Paclitaxel Hybrids Leading to Enhanced Biological Activity ⬇️

artículo científico publicado el 26 de agosto de 2011

Design, synthesis, and biological evaluation of new-generation taxoids

scientific article published on 09 May 2008

Design, synthesis, and biological evaluation of novel C14-C3'BzN-linked macrocyclic taxoids

artículo científico publicado en 2008

Design, synthesis, and biological evaluation of potent discodermolide fluorescent and photoaffinity molecular probes

artículo científico publicado en 2005

Design, synthesis, and evaluation of analogues of (+)-14-normethyldiscodermolide.

artículo científico publicado en 2005

Design, synthesis, and evaluation of carbamate-substituted analogues of (+)-discodermolide.

artículo científico publicado en 2005

Detection of human betaV-tubulin expression in epithelial cancer cell lines by tubulin proteomics

artículo científico publicado en 2005

Differential mitotic responses to microtubule-stabilizing and -destabilizing drugs

artículo científico publicado en 2002

Direct Analysis of Tubulin Expression in Cancer Cell Lines by Electrospray Ionization Mass Spectrometry ⬇️

artículo científico publicado el 21 de octubre de 2003

Distinct mechanisms of taxol-induced serine phosphorylation of the 66-kDa Shc isoform in A549 and RAW 264.7 cells

artículo científico publicado en 2002

Elevated levels of microtubule destabilizing factors in a Taxol-resistant/dependent A549 cell line with an alpha-tubulin mutation.

artículo científico publicado en 2003

Enhancement of the therapeutic efficacy of taxol by the mitogen-activated protein kinase kinase inhibitor CI-1040 in nude mice bearing human heterotransplants

artículo científico publicado en 2005

Epothilone B enhances surface EpCAM expression in ovarian cancer Hey cells ⬇️

artículo científico publicado el 2 de agosto de 2010

Eribulin disrupts EB1-microtubule plus-tip complex formation

artículo científico publicado en 2014

Exploiting MEK Inhibitor-Mediated Activation of ERα for Therapeutic Intervention in ER-Positive Ovarian Carcinoma ⬇️

artículo científico publicado el 4 de febrero de 2013

Exploring the mechanisms of action of the novel microtubule inhibitor vinflunine

artículo científico publicado en 2008

Expression of βV-Tubulin in Secretory Cells of the Fallopian Tube Epithelium Marks Cellular Atypia

artículo científico publicado en 2018

Gene expression and mitotic exit induced by microtubule-stabilizing drugs

artículo científico publicado en 2003

Germline mutations of the DNA repair pathways in uterine serous carcinoma.

artículo científico publicado en 2016

Hallmarks of molecular action of microtubule stabilizing agents: effects of epothilone B, ixabepilone, peloruside A, and laulimalide on microtubule conformation

artículo científico publicado en 2011

High expression of class III β-tubulin predicts good response to neoadjuvant taxane and doxorubicin/cyclophosphamide-based chemotherapy in estrogen receptor-negative breast cancer

artículo científico publicado en 2013

Highly concise routes to epothilones: the total synthesis and evaluation of epothilone 490.

artículo científico publicado en 2002

Identifying the semantic and textual differences between two versions of a program

Improved Dose-Response Relationship of (+)-Discodermolide-Taxol Hybrid Congeners.

artículo científico publicado en 2018

Increased levels of a unique post-translationally modified betaIVb-tubulin isotype in liver cancer

artículo científico publicado en 2008

Insights into 4E-BP1 and p53 mediated regulation of accelerated cell senescence ⬇️

artículo científico publicado el 1 de enero de 2011

Insights into the mechanism of microtubule stabilization by Taxol.

artículo científico publicado en 2006

Insulin-like growth factor 2 expression modulates Taxol resistance and is a candidate biomarker for reduced disease-free survival in ovarian cancer.

artículo científico publicado en 2010

Introduction. The novel microtubule inhibitor vinflunine

artículo científico publicado en 2008

Low concentrations of taxol cause mitotic delay followed by premature dissociation of p55CDC from Mad2 and BubR1 and abrogation of the spindle checkpoint, leading to aneuploidy

artículo científico publicado en 2005

Mechanisms of Taxol resistance related to microtubules. ⬇️

artículo científico publicado en 2003

Methods in tubulin proteomics

artículo científico publicado en 2010

Nature as a remarkable chemist: a personal story of the discovery and development of Taxol

scientific article published on May 2014

Novel molecules that interact with microtubules and have functional activity similar to Taxol™ ⬇️

artículo científico publicado el 15 de noviembre de 2001

Personal recollections on the early development of taxol

artículo científico publicado en 2004

Phase I clinical and pharmacokinetic study of BMS-247550, a novel derivative of epothilone B, in solid tumors

artículo científico publicado en 2004

Potentiation of taxol efficacy and by discodermolide in ovarian carcinoma xenograft-bearing mice

artículo científico publicado en 2006

Proteomics of cancer cell lines resistant to microtubule-stabilizing agents.

artículo científico publicado en 2013

Reflections on My Life with Taxol

scientific article published on 02 April 2019

Resistance to discodermolide, a microtubule-stabilizing agent and senescence inducer, is 4E-BP1–dependent ⬇️

artículo científico publicado el 20 de diciembre de 2010

Stathmin/Op18 is a novel mediator of vinblastine activity

artículo científico publicado en 2008

Structural Basis of Microtubule Stabilization by Discodermolide.

artículo científico publicado en 2017

Structural Evidence for Cooperative Microtubule Stabilization by Taxol and the Endogenous Dynamics Regulator MAP4 ⬇️

artículo científico publicado el 6 de febrero de 2012

Structural Refinement of the Tubulin Ligand (+)-Discodermolide to Attenuate Chemotherapy-Mediated Senescence

artículo científico publicado en 2020

Synergistic suppression of microtubule dynamics by discodermolide and paclitaxel in non-small cell lung carcinoma cells

artículo científico publicado en 2004

Synthesis and Biological Evaluation of Novel 3'-Difluorovinyl Taxoids

artículo científico publicado en 2012

TP53 hot spot mutations in ovarian cancer: selective resistance to microtubule stabilizers in vitro and differential survival outcomes from The Cancer Genome Atlas

artículo científico publicado en 2015

Targeting protein translation in human non small cell lung cancer via combined MEK and mammalian target of rapamycin suppression

artículo científico publicado en 2007

Taxol Analogues Exhibit Differential Effects on Photoaffinity Labeling of β-Tubulin and the Multidrug Resistance Associated P-Glycoprotein.

artículo científico publicado en 2018

Taxol®: The First Microtubule Stabilizing Agent

artículo científico publicado en 2017

Termination of Protofilament Elongation by Eribulin Induces Lattice Defects that Promote Microtubule Catastrophes

artículo científico publicado en 2016

The effect of ketoconazole on the pharmacokinetics and pharmacodynamics of ixabepilone: a first in class epothilone B analogue in late-phase clinical development.

artículo científico publicado en 2008

The interaction between mitotic checkpoint proteins, CENP-E and BubR1, is diminished in epothilone B-resistant A549 cells

artículo científico publicado en 2010

The microtubule stabilizing agent discodermolide is a potent inducer of accelerated cell senescence

artículo científico publicado en 2005

Tissue microarray analysis of hormonal signaling pathways in uterine carcinosarcoma

artículo científico publicado en 2009

Total Synthesis of(–)-Epothilone B: An Extension of the Suzuki Coupling Method and Insights into Structure–Activity Relationships of the Epothilones

artículo científico publicado en 1997

Tubulin proteomics: towards breaking the code.

artículo científico publicado en 2008

Use of the tubulin bound paclitaxel conformation for structure-based rational drug design

artículo científico publicado en 2005

Using Static Analysis to Reduce Dynamic Analysis Overhead

Using peer-led team learning to increase participation and success of under-represented groups in introductory computer science

scholarly article by Susan Band Horwitz et al published 4 March 2009 in SIGCSE bulletin

Validation of the pharmacodynamics of BMS-247550, an analogue of epothilone B, during a phase I clinical study

artículo científico publicado en 2002

Wild-type class I beta-tubulin sensitizes Taxol-resistant breast adenocarcinoma cells harboring a beta-tubulin mutation

artículo científico publicado en 2007

Lista de obras de Susan Band Horwitz

2-(m-Azidobenzoyl)taxol binds differentially to distinct β-tubulin isotypes

A Conversation with Susan Band Horwitz

A Symposium in Honor of Richard G. Powell, a Long-Time Associate Editor of the Journal of Natural Products

A highly epothilone B-resistant A549 cell line with mutations in tubulin that confer drug dependence

A label‐free mass spectrometry method for relative quantitation of β‐tubulin isotype expression in human tumor tissue ⬇️

A photoaffinity analogue of discodermolide specifically labels a peptide in beta-tubulin

Activation of the steroid and xenobiotic receptor (human pregnane X receptor) by nontaxane microtubule-stabilizing agents

Analysis of tubulin isotypes and mutations from taxol-resistant cells by combined isoelectrofocusing and mass spectrometry

Characterization of a human βV‐tubulin antibody and expression of this isotype in normal and malignant human tissue ⬇️

Correction: Exploiting MEK Inhibitor-Mediated Activation of ERα for Therapeutic Intervention in ER-Positive Ovarian Carcinoma

Design and Synthesis of (+)-Discodermolide–Paclitaxel Hybrids Leading to Enhanced Biological Activity ⬇️

Design, synthesis, and biological evaluation of new-generation taxoids

Design, synthesis, and biological evaluation of novel C14-C3'BzN-linked macrocyclic taxoids

Design, synthesis, and biological evaluation of potent discodermolide fluorescent and photoaffinity molecular probes

Design, synthesis, and evaluation of analogues of (+)-14-normethyldiscodermolide.

Design, synthesis, and evaluation of carbamate-substituted analogues of (+)-discodermolide.

Detection of human betaV-tubulin expression in epithelial cancer cell lines by tubulin proteomics

Differential mitotic responses to microtubule-stabilizing and -destabilizing drugs

Direct Analysis of Tubulin Expression in Cancer Cell Lines by Electrospray Ionization Mass Spectrometry ⬇️

Distinct mechanisms of taxol-induced serine phosphorylation of the 66-kDa Shc isoform in A549 and RAW 264.7 cells

Elevated levels of microtubule destabilizing factors in a Taxol-resistant/dependent A549 cell line with an alpha-tubulin mutation.

Enhancement of the therapeutic efficacy of taxol by the mitogen-activated protein kinase kinase inhibitor CI-1040 in nude mice bearing human heterotransplants

Epothilone B enhances surface EpCAM expression in ovarian cancer Hey cells ⬇️

Eribulin disrupts EB1-microtubule plus-tip complex formation

Exploiting MEK Inhibitor-Mediated Activation of ERα for Therapeutic Intervention in ER-Positive Ovarian Carcinoma ⬇️

Exploring the mechanisms of action of the novel microtubule inhibitor vinflunine

Expression of βV-Tubulin in Secretory Cells of the Fallopian Tube Epithelium Marks Cellular Atypia

Gene expression and mitotic exit induced by microtubule-stabilizing drugs

Germline mutations of the DNA repair pathways in uterine serous carcinoma.

Hallmarks of molecular action of microtubule stabilizing agents: effects of epothilone B, ixabepilone, peloruside A, and laulimalide on microtubule conformation

High expression of class III β-tubulin predicts good response to neoadjuvant taxane and doxorubicin/cyclophosphamide-based chemotherapy in estrogen receptor-negative breast cancer

Highly concise routes to epothilones: the total synthesis and evaluation of epothilone 490.

Identifying the semantic and textual differences between two versions of a program

Improved Dose-Response Relationship of (+)-Discodermolide-Taxol Hybrid Congeners.

Increased levels of a unique post-translationally modified betaIVb-tubulin isotype in liver cancer

Insights into 4E-BP1 and p53 mediated regulation of accelerated cell senescence ⬇️

Insights into the mechanism of microtubule stabilization by Taxol.

Insulin-like growth factor 2 expression modulates Taxol resistance and is a candidate biomarker for reduced disease-free survival in ovarian cancer.

Introduction. The novel microtubule inhibitor vinflunine

Low concentrations of taxol cause mitotic delay followed by premature dissociation of p55CDC from Mad2 and BubR1 and abrogation of the spindle checkpoint, leading to aneuploidy

Mechanisms of Taxol resistance related to microtubules. ⬇️

Methods in tubulin proteomics

Nature as a remarkable chemist: a personal story of the discovery and development of Taxol

Novel molecules that interact with microtubules and have functional activity similar to Taxol™ ⬇️

Personal recollections on the early development of taxol

Phase I clinical and pharmacokinetic study of BMS-247550, a novel derivative of epothilone B, in solid tumors

Potentiation of taxol efficacy and by discodermolide in ovarian carcinoma xenograft-bearing mice

Proteomics of cancer cell lines resistant to microtubule-stabilizing agents.

Reflections on My Life with Taxol

Resistance to discodermolide, a microtubule-stabilizing agent and senescence inducer, is 4E-BP1–dependent ⬇️

Stathmin/Op18 is a novel mediator of vinblastine activity

Structural Basis of Microtubule Stabilization by Discodermolide.

Structural Evidence for Cooperative Microtubule Stabilization by Taxol and the Endogenous Dynamics Regulator MAP4 ⬇️

Structural Refinement of the Tubulin Ligand (+)-Discodermolide to Attenuate Chemotherapy-Mediated Senescence

Synergistic suppression of microtubule dynamics by discodermolide and paclitaxel in non-small cell lung carcinoma cells

Synthesis and Biological Evaluation of Novel 3'-Difluorovinyl Taxoids

TP53 hot spot mutations in ovarian cancer: selective resistance to microtubule stabilizers in vitro and differential survival outcomes from The Cancer Genome Atlas

Targeting protein translation in human non small cell lung cancer via combined MEK and mammalian target of rapamycin suppression

Taxol Analogues Exhibit Differential Effects on Photoaffinity Labeling of β-Tubulin and the Multidrug Resistance Associated P-Glycoprotein.

Taxol®: The First Microtubule Stabilizing Agent

Termination of Protofilament Elongation by Eribulin Induces Lattice Defects that Promote Microtubule Catastrophes

The effect of ketoconazole on the pharmacokinetics and pharmacodynamics of ixabepilone: a first in class epothilone B analogue in late-phase clinical development.

The interaction between mitotic checkpoint proteins, CENP-E and BubR1, is diminished in epothilone B-resistant A549 cells

The microtubule stabilizing agent discodermolide is a potent inducer of accelerated cell senescence

Tissue microarray analysis of hormonal signaling pathways in uterine carcinosarcoma

Total Synthesis of(–)-Epothilone B: An Extension of the Suzuki Coupling Method and Insights into Structure–Activity Relationships of the Epothilones

Tubulin proteomics: towards breaking the code.

Use of the tubulin bound paclitaxel conformation for structure-based rational drug design

Using Static Analysis to Reduce Dynamic Analysis Overhead

Using peer-led team learning to increase participation and success of under-represented groups in introductory computer science

Validation of the pharmacodynamics of BMS-247550, an analogue of epothilone B, during a phase I clinical study

Wild-type class I beta-tubulin sensitizes Taxol-resistant breast adenocarcinoma cells harboring a beta-tubulin mutation