Lista de obras - Giulio Maria Pasinetti - Dominio Público Uruguay

A comprehensive database and analysis framework to incorporate multiscale data types and enable integrated analysis of bioactive polyphenols

artículo científico publicado en 2018

A ketogenic diet as a potential novel therapeutic intervention in amyotrophic lateral sclerosis

artículo científico publicado en 2006

Amyloid precursor protein mRNA encoding the Kunitz protease inhibitor domain is increased by kainic acid-induced seizures in rat hippocampus

artículo científico publicado el 1 de diciembre de 1992

An Efficient Synthesis of Deoxyrhapontigenin-3-O-β-D-glucuronide, a Brain-targeted Derivative of Dietary Resveratrol, and its Precursor 4'-O-Me-Resveratrol

scientific article published on 07 May 2019

An Extract of Artemisia dracunculus L. Promotes Psychological Resilience in a Mouse Model of Depression

artículo científico publicado en 2018

Anti-aggregation Effects of Phenolic Compounds on α-synuclein

artículo científico publicado en 2020

Association Between Preoperative Malnutrition and Postoperative Delirium After Hip Fracture Surgery in Older Adults.

artículo científico publicado en 2017

Autonomic Nervous System Dysfunctions as a Basis for a Predictive Model of Risk of Neurological Disorders in Subjects with Prior History of Traumatic Brain Injury: Implications in Alzheimer's Disease.

artículo científico publicado en 2016

Bioavailability of gallic acid and catechins from grape seed polyphenol extract is improved by repeated dosing in rats: implications for treatment in Alzheimer's disease

artículo científico publicado en 2009

Brain-targeted proanthocyanidin metabolites for Alzheimer's disease treatment

artículo científico publicado en 2012

Caloric Intake, Dietary Lifestyles, Macronutrient Composition, and Alzheimer′ Disease Dementia ⬇️

artículo científico publicado el 19 de junio de 2011

Carvedilol as a potential novel agent for the treatment of Alzheimer's disease

artículo científico publicado en 2010

Cerebrospinal fluid ceramides from patients with multiple sclerosis impair neuronal bioenergetics

artículo científico publicado en 2014

Chemical investigation of commercial grape seed derived products to assess quality and detect adulteration

artículo científico publicado en 2014

Childhood and adolescent obesity and long-term cognitive consequences during aging.

artículo científico publicado en 2014

Clusterin (apoJ) Alters the Aggregation of Amyloid β-Peptide (Aβ1-42) and Forms Slowly Sedimenting Aβ Complexes That Cause Oxidative Stress ⬇️

artículo científico publicado el 1 de noviembre de 1995

Complement C1qB and C4 mRNAs responses to lesioning in rat brain

artículo científico publicado el 1 de noviembre de 1992

Complement mRNA in the mammalian brain: responses to Alzheimer's disease and experimental brain lesioning

artículo científico publicado el 1 de noviembre de 1992

Cyclooxygenase (COX)-2 and COX-1 Potentiate β-Amyloid Peptide Generation through Mechanisms That Involve γ-Secretase Activity ⬇️

artículo científico publicado el 24 de septiembre de 2003

Cyclooxygenase-2 expression is increased in frontal cortex of Alzheimer's disease brain ⬇️

artículo científico publicado el 1 de noviembre de 1998

Decortication and striatal mRNA: increases of mRNA for fibronectin, but not of NCAM or alpha-1 tubulin

artículo científico publicado el 1 de octubre de 1992

Decreased Level of Olfactory Receptors in Blood Cells Following Traumatic Brain Injury and Potential Association with Tauopathy ⬇️

artículo científico publicado el 1 de enero de 2013

Development and validation of an ultra-high performance liquid chromatography/triple quadrupole mass spectrometry method for analyzing microbial-derived grape polyphenol metabolites

artículo científico publicado en 2018

Dietary composition modulates brain mass and solubilizable Abeta levels in a mouse model of aggressive Alzheimer's amyloid pathology

artículo científico publicado en 2009

Dietary polyphenols enhance optogenetic recall of fear memory in hippocampal dentate gyrus granule neuron subpopulations

scholarly article published 2018

Dietary polyphenols promote resilience against sleep deprivation-induced cognitive impairment by activating protein translation

artículo científico publicado en 2018

Dietary supplementation with decaffeinated green coffee improves diet-induced insulin resistance and brain energy metabolism in mice

artículo científico publicado en 2012

Diffuse Disconnectivity in tBi: a resting state fMri anD Dti stuDy ⬇️

artículo científico publicado en 2012

Disappearance of GAD-mRNA and tyrosine hydroxylase in substantia nigra following striatal ibotenic acid lesions: Evidence for transneuronal regression ⬇️

artículo científico publicado el 1 de mayo de 1991

Effects of grape seed-derived polyphenols on amyloid beta-protein self-assembly and cytotoxicity

artículo científico publicado en 2008

Efficient Chemical Synthesis of (Epi)catechin Glucuronides: Brain-Targeted Metabolites for Treatment of Alzheimer's Disease and Other Neurological Disorders

artículo científico publicado en 2020

Elevated Plasma MCP-1 Concentration Following Traumatic Brain Injury as a Potential “Predisposition” Factor Associated with an Increased Risk for Subsequent Development of Alzheimer's Disease ⬇️

artículo científico publicado el 1 de enero de 2012

Enzymatic synthesis of substituted epicatechins for bioactivity studies in neurological disorders

artículo científico publicado en 2011

Epigenetic mechanisms linking diabetes and synaptic impairments

artículo científico publicado en 2013

Epigenetic modifications by polyphenolic compounds alter gene expression in the hippocampus

article

Epigenetic modulation of inflammation and synaptic plasticity promotes resilience against stress in mice

artículo científico publicado en 2018

Erratum. The granin VGF promotes genesis of secretory vesicles, and regulates circulating catecholamine levels and blood pressure

artículo científico publicado en 2015

Expression profile of genes associated with antimetastatic gene: nm23-mediated metastasis inhibition in breast carcinoma cells

artículo científico publicado en 2004

Flavonoids and isoflavonoids: from plant biology to agriculture and neuroscience

artículo científico publicado en 2010

From dorzolamide 2%/timolol 0.5% to brinzolamide 1%/timolol 0.5% fixed combination: a 6-month, multicenter, open-label tolerability switch study ⬇️

artículo científico publicado el 16 de junio de 2011

GSPE interferes with tau aggregation in vivo: implication for treating tauopathy ⬇️

artículo científico publicado el 4 de noviembre de 2011

Glucuronidated Flavonoids in Neurological Protection: Structural Analysis and Approaches for Chemical and Biological Synthesis

artículo científico publicado en 2017

Glucuronidation of Methylated Quercetin Derivatives: Chemical and Biochemical Approaches

artículo científico publicado en 2020

Grape Derived Polyphenols Attenuate Tau Neuropathology in a Mouse Model of Alzheimer's Disease ⬇️

artículo científico publicado el 1 de enero de 2010

Grape seed polyphenolic extract specifically decreases aβ*56 in the brains of Tg2576 mice

artículo científico publicado en 2011

Grape-Derived Polyphenols Ameliorate Stress-Induced Depression by Regulating Synaptic Plasticity

artículo científico publicado en 2019

Grape-derived polyphenolics prevent Abeta oligomerization and attenuate cognitive deterioration in a mouse model of Alzheimer's disease

artículo científico publicado en 2008

Grape-seed polyphenolic extract improves the eye phenotype in a Drosophila model of tauopathy

artículo científico publicado en 2010

IVIG immunotherapy protects against synaptic dysfunction in Alzheimer's disease through complement anaphylatoxin C5a-mediated AMPA-CREB-C/EBP signaling pathway

artículo científico publicado en 2013

Identification of G-protein coupled receptor kinase 2 in paired helical filaments and neurofibrillary tangles

artículo científico publicado en 2006

Identification of antihypertensive drugs which inhibit amyloid-beta protein oligomerization

artículo científico publicado en 2009

Increased neuronal injury in transgenic mice with neuronal overexpression of human cyclooxygenase-2 is reversed by hypothermia and rofecoxib treatment

artículo científico publicado en 2007

Induction of cyclooxygenase (COX)-2 but not COX-1 gene expression in apoptotic cell death ⬇️

artículo científico publicado el 14 de agosto de 1998

Influence of diabetes on plasma pharmacokinetics and brain bioavailability of grape polyphenols and their phase II metabolites in the Zucker diabetic fatty rat.

artículo científico publicado en 2017

Inhibiting amyloid β-protein assembly: Size-activity relationships among grape seed-derived polyphenols

artículo científico publicado en 2015

Insulin receptor deficits in schizophrenia and in cellular and animal models of insulin receptor dysfunction

artículo científico publicado en 2006

Investigation of nebivolol as a novel therapeutic agent for the treatment of Alzheimer's disease

artículo científico publicado en 2013

Is there a future for cyclo-oxygenase inhibitors in Alzheimer's disease?

artículo científico publicado en 2006

Molecular and Morphological Correlates Following Neuronal Deafferentation: A Cortico-Striatal Model ⬇️

artículo científico publicado el 1 de enero de 1991

Molecular topology as novel strategy for discovery of drugs with aβ lowering and anti-aggregation dual activities for Alzheimer's disease

artículo científico publicado en 2014

Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction

artículo científico publicado en 2006

Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse models

artículo científico publicado en 2013

Novel Role of Red Wine-Derived Polyphenols in the Prevention of Alzheimerʼs Disease Dementia and Brain Pathology: Experimental Approaches and Clinical Implications ⬇️

artículo científico publicado el 21 de septiembre de 2012

Overexpression of wild type but not an FAD mutant presenilin-1 promotes neurogenesis in the hippocampus of adult mice

artículo científico publicado en 2002

PGC-1alpha expression decreases in the Alzheimer disease brain as a function of dementia

artículo científico publicado en 2009

POTENTIAL APPLICATION OF GRAPE DERIVED POLYPHENOLS IN HUNTINGTON'S DISEASE

artículo científico publicado en 2010

Paired helical filaments from Alzheimer disease brain induce intracellular accumulation of Tau protein in aggresomes

artículo científico publicado en 2012

Peroxisome Proliferator Activator Receptor Gamma Coactivator-1α Overexpression in Amyotrophic Lateral Sclerosis: A Tale of Two Transgenics

artículo científico publicado en 2020

Peroxisome proliferator activator receptor gamma coactivator-1alpha (PGC-1α) improves motor performance and survival in a mouse model of amyotrophic lateral sclerosis

artículo científico publicado en 2011

Preclinical study of dimebon on β-amyloid-mediated neuropathology in Alzheimer's disease

artículo científico publicado en 2011

Principles of inflammasome priming and inhibition: Implications for psychiatric disorders

scientific article published on 11 June 2018

Prophylactic effect of flavanol rich preparation metabolites in promoting resilience to a mouse model of social stress

artículo científico publicado en 2020

Protective roles of intestinal microbiota derived short chain fatty acids in Alzheimer's disease-type beta-amyloid neuropathological mechanisms

artículo científico publicado en 2017

Recommendations for Development of Botanical Polyphenols as "Natural Drugs" for Promotion of Resilience Against Stress-Induced Depression and Cognitive Impairment

artículo científico publicado en 2016

Recommendations for Development of New Standardized Forms of Cocoa Breeds and Cocoa Extract Processing for the Prevention of Alzheimer's Disease: Role of Cocoa in Promotion of Cognitive Resilience and Healthy Brain Aging

artículo científico publicado en 2015

Role of complement systems in IVIG mediated attenuation of cognitive deterioration in Alzheimer's disease

artículo científico

Role of grape seed polyphenols in Alzheimer&rsquo;s disease neuropathology ⬇️

artículo científico publicado el 1 de agosto de 2010

Role of intestinal microbiota in the generation of polyphenol-derived phenolic acid mediated attenuation of Alzheimer's disease β-amyloid oligomerization.

artículo científico publicado en 2015

Role of standardized grape polyphenol preparation as a novel treatment to improve synaptic plasticity through attenuation of features of metabolic syndrome in a mouse model

artículo científico publicado en 2013

S100A7, a novel Alzheimer's disease biomarker with non-amyloidogenic alpha-secretase activity acts via selective promotion of ADAM-10

artículo científico publicado en 2009

SCFFbx2-E3-ligase-mediated degradation of BACE1 attenuates Alzheimer's disease amyloidosis and improves synaptic function

artículo científico publicado en 2010

Select non-coding RNA in blood components provide novel clinically accessible biological surrogates for improved identification of traumatic brain injury in OEF/OIF Veterans.

artículo científico publicado en 2012

Selective brain penetrable Nurr1 transactivator for treating Parkinson's disease

artículo científico publicado en 2016

Simultaneous bilateral femoral neck fracture and end-stage renal disease in a 76-year-old woman: a case report

artículo científico publicado en 2015

Sirtuins as therapeutic targets of ALS ⬇️

artículo científico publicado el 16 de julio de 2013

Striatal responses to decortication. I. Dopaminergic and astrocytic activities ⬇️

artículo científico publicado el 20 de diciembre de 1991

Suppression of Presymptomatic Oxidative Stress and Inflammation in Neurodegeneration by Grape-Derived Polyphenols

scholarly article by Francis Herman et al published 2018 in Frontiers in Pharmacology

Synthesis and quantitative analysis of plasma-targeted metabolites of catechin and epicatechin

artículo científico publicado en 2015

Systems biology in the study of neurological disorders: focus on Alzheimer's disease

artículo científico publicado en 2008

Targeted analysis of microbial-generated phenolic acid metabolites derived from grape flavanols by gas chromatography-triple quadrupole mass spectrometry

artículo científico publicado en 2018

Targeting multiple pathogenic mechanisms with polyphenols for the treatment of Alzheimer's disease-experimental approach and therapeutic implications

artículo científico publicado en 2014

The NLRP3 Inflammasome as a Critical Actor in the Inflammaging Process

artículo científico publicado en 2020

The Use of Antimicrobial and Antiviral Drugs in Alzheimer's Disease

artículo científico publicado en 2020

The Viral Hypothesis in Alzheimer's Disease: Novel Insights and Pathogen-Based Biomarkers

artículo científico publicado en 2020

The effect of obesity and repeated exposure on pharmacokinetic response to grape polyphenols in humans

artículo científico publicado en 2017

The gut microbiota composition affects dietary polyphenols-mediated cognitive resilience in mice by modulating the bioavailability of phenolic acids

article

Transgenic neuronal expression of proopiomelanocortin attenuates hyperphagic response to fasting and reverses metabolic impairments in leptin-deficient obese mice

artículo científico publicado en 2003

Unintended effects of cardiovascular drugs on the pathogenesis of Alzheimer's disease

artículo científico publicado en 2013

Lista de obras de Giulio Maria Pasinetti

A comprehensive database and analysis framework to incorporate multiscale data types and enable integrated analysis of bioactive polyphenols

A ketogenic diet as a potential novel therapeutic intervention in amyotrophic lateral sclerosis

Amyloid precursor protein mRNA encoding the Kunitz protease inhibitor domain is increased by kainic acid-induced seizures in rat hippocampus

An Efficient Synthesis of Deoxyrhapontigenin-3-O-β-D-glucuronide, a Brain-targeted Derivative of Dietary Resveratrol, and its Precursor 4'-O-Me-Resveratrol

An Extract of Artemisia dracunculus L. Promotes Psychological Resilience in a Mouse Model of Depression

Anti-aggregation Effects of Phenolic Compounds on α-synuclein

Association Between Preoperative Malnutrition and Postoperative Delirium After Hip Fracture Surgery in Older Adults.

Autonomic Nervous System Dysfunctions as a Basis for a Predictive Model of Risk of Neurological Disorders in Subjects with Prior History of Traumatic Brain Injury: Implications in Alzheimer's Disease.

Bioavailability of gallic acid and catechins from grape seed polyphenol extract is improved by repeated dosing in rats: implications for treatment in Alzheimer's disease

Brain-targeted proanthocyanidin metabolites for Alzheimer's disease treatment

Caloric Intake, Dietary Lifestyles, Macronutrient Composition, and Alzheimer′ Disease Dementia ⬇️

Carvedilol as a potential novel agent for the treatment of Alzheimer's disease

Cerebrospinal fluid ceramides from patients with multiple sclerosis impair neuronal bioenergetics

Chemical investigation of commercial grape seed derived products to assess quality and detect adulteration

Childhood and adolescent obesity and long-term cognitive consequences during aging.

Clusterin (apoJ) Alters the Aggregation of Amyloid β-Peptide (Aβ1-42) and Forms Slowly Sedimenting Aβ Complexes That Cause Oxidative Stress ⬇️

Complement C1qB and C4 mRNAs responses to lesioning in rat brain

Complement mRNA in the mammalian brain: responses to Alzheimer's disease and experimental brain lesioning

Cyclooxygenase (COX)-2 and COX-1 Potentiate β-Amyloid Peptide Generation through Mechanisms That Involve γ-Secretase Activity ⬇️

Cyclooxygenase-2 expression is increased in frontal cortex of Alzheimer's disease brain ⬇️

Decortication and striatal mRNA: increases of mRNA for fibronectin, but not of NCAM or alpha-1 tubulin

Decreased Level of Olfactory Receptors in Blood Cells Following Traumatic Brain Injury and Potential Association with Tauopathy ⬇️

Development and validation of an ultra-high performance liquid chromatography/triple quadrupole mass spectrometry method for analyzing microbial-derived grape polyphenol metabolites

Dietary composition modulates brain mass and solubilizable Abeta levels in a mouse model of aggressive Alzheimer's amyloid pathology

Dietary polyphenols enhance optogenetic recall of fear memory in hippocampal dentate gyrus granule neuron subpopulations

Dietary polyphenols promote resilience against sleep deprivation-induced cognitive impairment by activating protein translation

Dietary supplementation with decaffeinated green coffee improves diet-induced insulin resistance and brain energy metabolism in mice

Diffuse Disconnectivity in tBi: a resting state fMri anD Dti stuDy ⬇️

Disappearance of GAD-mRNA and tyrosine hydroxylase in substantia nigra following striatal ibotenic acid lesions: Evidence for transneuronal regression ⬇️

Effects of grape seed-derived polyphenols on amyloid beta-protein self-assembly and cytotoxicity

Efficient Chemical Synthesis of (Epi)catechin Glucuronides: Brain-Targeted Metabolites for Treatment of Alzheimer's Disease and Other Neurological Disorders

Elevated Plasma MCP-1 Concentration Following Traumatic Brain Injury as a Potential “Predisposition” Factor Associated with an Increased Risk for Subsequent Development of Alzheimer's Disease ⬇️

Enzymatic synthesis of substituted epicatechins for bioactivity studies in neurological disorders

Epigenetic mechanisms linking diabetes and synaptic impairments

Epigenetic modifications by polyphenolic compounds alter gene expression in the hippocampus

Epigenetic modulation of inflammation and synaptic plasticity promotes resilience against stress in mice

Erratum. The granin VGF promotes genesis of secretory vesicles, and regulates circulating catecholamine levels and blood pressure

Expression profile of genes associated with antimetastatic gene: nm23-mediated metastasis inhibition in breast carcinoma cells

Flavonoids and isoflavonoids: from plant biology to agriculture and neuroscience

From dorzolamide 2%/timolol 0.5% to brinzolamide 1%/timolol 0.5% fixed combination: a 6-month, multicenter, open-label tolerability switch study ⬇️

GSPE interferes with tau aggregation in vivo: implication for treating tauopathy ⬇️

Glucuronidated Flavonoids in Neurological Protection: Structural Analysis and Approaches for Chemical and Biological Synthesis

Glucuronidation of Methylated Quercetin Derivatives: Chemical and Biochemical Approaches

Grape Derived Polyphenols Attenuate Tau Neuropathology in a Mouse Model of Alzheimer's Disease ⬇️

Grape seed polyphenolic extract specifically decreases aβ*56 in the brains of Tg2576 mice

Grape-Derived Polyphenols Ameliorate Stress-Induced Depression by Regulating Synaptic Plasticity

Grape-derived polyphenolics prevent Abeta oligomerization and attenuate cognitive deterioration in a mouse model of Alzheimer's disease

Grape-seed polyphenolic extract improves the eye phenotype in a Drosophila model of tauopathy

IVIG immunotherapy protects against synaptic dysfunction in Alzheimer's disease through complement anaphylatoxin C5a-mediated AMPA-CREB-C/EBP signaling pathway

Identification of G-protein coupled receptor kinase 2 in paired helical filaments and neurofibrillary tangles

Identification of antihypertensive drugs which inhibit amyloid-beta protein oligomerization

Increased neuronal injury in transgenic mice with neuronal overexpression of human cyclooxygenase-2 is reversed by hypothermia and rofecoxib treatment

Induction of cyclooxygenase (COX)-2 but not COX-1 gene expression in apoptotic cell death ⬇️

Influence of diabetes on plasma pharmacokinetics and brain bioavailability of grape polyphenols and their phase II metabolites in the Zucker diabetic fatty rat.

Inhibiting amyloid β-protein assembly: Size-activity relationships among grape seed-derived polyphenols

Insulin receptor deficits in schizophrenia and in cellular and animal models of insulin receptor dysfunction

Investigation of nebivolol as a novel therapeutic agent for the treatment of Alzheimer's disease

Is there a future for cyclo-oxygenase inhibitors in Alzheimer's disease?

Molecular and Morphological Correlates Following Neuronal Deafferentation: A Cortico-Striatal Model ⬇️

Molecular topology as novel strategy for discovery of drugs with aβ lowering and anti-aggregation dual activities for Alzheimer's disease

Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction

Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse models

Novel Role of Red Wine-Derived Polyphenols in the Prevention of Alzheimerʼs Disease Dementia and Brain Pathology: Experimental Approaches and Clinical Implications ⬇️

Overexpression of wild type but not an FAD mutant presenilin-1 promotes neurogenesis in the hippocampus of adult mice

PGC-1alpha expression decreases in the Alzheimer disease brain as a function of dementia

POTENTIAL APPLICATION OF GRAPE DERIVED POLYPHENOLS IN HUNTINGTON'S DISEASE

Paired helical filaments from Alzheimer disease brain induce intracellular accumulation of Tau protein in aggresomes

Peroxisome Proliferator Activator Receptor Gamma Coactivator-1α Overexpression in Amyotrophic Lateral Sclerosis: A Tale of Two Transgenics

Peroxisome proliferator activator receptor gamma coactivator-1alpha (PGC-1α) improves motor performance and survival in a mouse model of amyotrophic lateral sclerosis

Preclinical study of dimebon on β-amyloid-mediated neuropathology in Alzheimer's disease

Principles of inflammasome priming and inhibition: Implications for psychiatric disorders

Prophylactic effect of flavanol rich preparation metabolites in promoting resilience to a mouse model of social stress

Protective roles of intestinal microbiota derived short chain fatty acids in Alzheimer's disease-type beta-amyloid neuropathological mechanisms

Recommendations for Development of Botanical Polyphenols as "Natural Drugs" for Promotion of Resilience Against Stress-Induced Depression and Cognitive Impairment

Recommendations for Development of New Standardized Forms of Cocoa Breeds and Cocoa Extract Processing for the Prevention of Alzheimer's Disease: Role of Cocoa in Promotion of Cognitive Resilience and Healthy Brain Aging

Role of complement systems in IVIG mediated attenuation of cognitive deterioration in Alzheimer's disease

Role of grape seed polyphenols in Alzheimer&amp;rsquo;s disease neuropathology ⬇️

Role of intestinal microbiota in the generation of polyphenol-derived phenolic acid mediated attenuation of Alzheimer's disease β-amyloid oligomerization.

Role of standardized grape polyphenol preparation as a novel treatment to improve synaptic plasticity through attenuation of features of metabolic syndrome in a mouse model

Role of grape seed polyphenols in Alzheimer’s disease neuropathology ⬇️