Lista de obras - Irja Lutsar - Dominio Público Uruguay

A CCL5 Haplotype Is Associated with Low Seropositivity Rate of HCV Infection in People Who Inject Drugs

artículo científico publicado en 2016

A highly sensitive method for the simultaneous UHPLC-MS/MS analysis of clonidine, morphine, midazolam and their metabolites in blood plasma using HFIP as the eluent additive

artículo científico publicado en 2017

Absence of genotypic drug resistance and presence of several naturally occurring polymorphisms of human immunodeficiency virus-1 CRF06_cpx in treatment-naive patients in Estonia

artículo científico publicado en 2009

Acute gastroenteritis hospitalizations after implementation of universal mass vaccination against rotavirus

scientific article published on 14 February 2020

Age-appropriate formulations including pharmaceutical excipients in neonatal medicines

artículo científico publicado en 2017

Ampicillin versus penicillin in the empiric therapy of extremely low-birthweight neonates at risk of early onset sepsis

artículo científico publicado en 2011

An optimised dosing regimen versus a standard dosing regimen of vancomycin for the treatment of late onset sepsis due to Gram-positive microorganisms in neonates and infants aged less than 90 days (NeoVanc): study protocol for a randomised controlle

artículo científico publicado en 2020

Antibiotic prescription preferences in paediatric outpatient setting in Estonia and Sweden

artículo científico publicado en 2013

Antibiotic therapy for pediatric community-acquired pneumonia: do we know when, what and for how long to treat?

artículo científico

Antiretroviral drug resistance and viral tropism in HIV-1 CRF06_cpx infected patients failing antiretroviral (ARV) therapy

artículo científico publicado en 2014

Association between HIV-1 tropism and CCR5 human haplotype E in a Caucasian population

artículo científico publicado en 2014

Association between TLR3 rs3775291 and resistance to HIV among highly exposed Caucasian intravenous drug users

artículo científico publicado en 2013

Association of IFNλ4 rs12979860 polymorphism with the acquisition of HCV and HIV infections among people who inject drugs

article

Blood loss related to participation in pharmacokinetic study in preterm neonates

artículo científico publicado en 2011

CCL3L1 copy number is a strong genetic determinant of HIV seropositivity in Caucasian intravenous drug users

artículo científico publicado en 2010

CCR5 haplotypes influence HCV serostatus in Caucasian intravenous drug users

artículo científico publicado en 2013

Central European Vaccination Advisory Group (CEVAG) guidance statement on recommendations for the introduction of HPV vaccines

artículo científico publicado en 2009

Characteristics of Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae and Contact to Animals in Estonia

artículo científico publicado en 2020

Characterization of integrase region polymorphisms in HIV type 1 CRF06_cpx viruses in treatment-naive patients in Estonia

artículo científico publicado en 2010

Clinical and pathological findings of fatal 2009-2010 pandemic influenza A (H1N1) infection in Estonia

artículo científico publicado en 2012

Clinical parameters predicting failure of empirical antibacterial therapy in early onset neonatal sepsis, identified by classification and regression tree analysis

artículo científico publicado en 2009

Clinical trials in neonatal sepsis

artículo científico

Co-infection with hepatitis C virus (HCV) in Estonian intravenous drug users HIV epidemic

artículo científico publicado en 2014

Coagulase negative staphylococcal sepsis in neonates: do we need to adapt vancomycin dose or target?

artículo científico publicado en 2016

Coagulase-Negative Staphylococci in Human Milk From Mothers of Preterm Compared With Term Neonates

artículo científico publicado en 2017

Comment on Pharmacokinetic Studies in Neonates: The Utility of an Opportunistic Sampling Design

artículo científico publicado en 2015

Comparison of two alternative study designs in assessment of medicines utilisation in neonates

artículo científico publicado en 2014

Correction: Geographic and Temporal Trends in the Molecular Epidemiology and Genetic Mechanisms of Transmitted HIV-1 Drug Resistance: An Individual-Patient- and Sequence-Level Meta-Analysis

artículo científico publicado en 2015

Current management of late onset neonatal bacterial sepsis in five European countries

artículo científico publicado en 2014

Design and structure of the Estonian HIV Cohort Study (E-HIV).

artículo científico publicado en 2015

Development and Evaluation of a Gentamicin Pharmacokinetic Model That Facilitates Opportunistic Gentamicin Therapeutic Drug Monitoring in Neonates and Infants

artículo científico publicado en 2016

Differences in T cell distribution and CCR5 expression in HIV-positive and HIV-exposed seronegative persons who inject drugs

artículo científico publicado en 2015

Discovery and development of safe-in-man broad-spectrum antiviral agents

scientific article published on 17 February 2020

DosOpt: A Tool for Personalized Bayesian Dose Adjustment of Vancomycin in Neonates

artículo científico publicado en 2017

Drug utilisation pattern and off-label use of medicines in Estonian neonatal units

artículo científico publicado en 2011

Dynamics of pertussis toxin IgG after symptomatic pertussis in children and adults

scientific article published on 11 March 2020

Emerging transmitted drug resistance in treatment-naïve human immunodeficiency virus-1 CRF06_cpx-infected patients in Estonia

artículo científico publicado en 2010

Epidemiological characteristics of pertussis in Estonia, Lithuania, Romania, the Czech Republic, Poland and Turkey-1945 to 2005.

artículo científico publicado en 2008

Estimated and reported incidence of pertussis in Estonian adults: A seroepidemiological study

artículo científico publicado en 2015

Evaluating Safety Reporting in Paediatric Antibiotic Trials, 2000-2016: A Systematic Review and Meta-Analysis

artículo científico publicado en 2017

First report of Wohlfahrtiimonas chitiniclastica from soft tissue and bone infection at an unusually high northern latitude

artículo científico publicado en 2014

Framework conditions facilitating paediatric clinical research ⬇️

artículo científico publicado el 23 de febrero de 2011

Full-length genome sequences of Estonian HIV-1 CRF06 and Eastern-European subtype A1 recombinant forms

article

GAPPS (Grading and Assessment of Pharmacokinetic-Pharmacodynamic Studies) a critical appraisal system for antimicrobial PKPD studies - development and application in pediatric antibiotic studies

scientific article published on 30 November 2019

Genetic Relatedness of Staphylococcus haemolyticus in Gut and Skin of Preterm Neonates and Breast Milk of Their Mothers.

artículo científico publicado en 2018

Genetic relatedness of Gram-negative bacteria colonizing gut and skin of neonates and mother's own milk

Genetic relatedness of coagulase-negative Staphylococci from gastrointestinal tract and blood of preterm neonates with late-onset sepsis

artículo científico publicado en 2013

Geographic and temporal trends in the molecular epidemiology and genetic mechanisms of transmitted HIV-1 drug resistance: an individual-patient- and sequence-level meta-analysis

artículo científico publicado en 2015

Global shortage of neonatal and paediatric antibiotic trials: rapid review

artículo científico publicado en 2017

Gut colonization by aerobic microorganisms is associated with route and type of nutrition in premature neonates

artículo científico publicado en 2015

HTLV-1/2 is rare among Eastern-European intravenous drug users (IDUs).

artículo científico publicado en 2015

Harmonisation in study design and outcomes in paediatric antibiotic clinical trials: a systematic review

artículo científico publicado en 2016

High variability in the dosing of commonly used antibiotics revealed by a Europe-wide point prevalence study: implications for research and dissemination

artículo científico publicado en 2015

Higher intake of coagulase-negative staphylococci from maternal milk promotes gut colonization with mecA-negative Staphylococcus epidermidis in preterm neonates

scientific article published on 03 August 2018

Hospitalised neonates in Estonia commonly receive potentially harmful excipients

artículo científico publicado en 2012

Human T-lymphotropic virus types 1 and 2 are rare among intravenous drug users in Eastern Europe

artículo científico publicado en 2016

Immunologic response to Hib tetanus toxoid conjugated vaccine coadministered with DTPa either mixed or in two separate injections in toddlers not primed with Hib vaccine

artículo científico publicado en 2007

Improved outcome in central nervous system aspergillosis, using voriconazole treatment

artículo científico publicado en 2005

In vitrosynergy of oxacillin and gentamicin against coagulase-negative staphylococci from blood cultures of neonates with late-onset sepsis

article

Infections due to Aspergillus terreus: a multicenter retrospective analysis of 83 cases

artículo científico publicado en 2004

Influence of interleukin 10 polymorphisms -592 and -1082 to the HIV, HBV and HCV serostatus among intravenous drug users

artículo científico publicado en 2014

Laboratory markers to determine clinical significance of coagulase-negative staphylococci in blood cultures.

artículo científico publicado en 2007

Low Temperature and Low UV Indexes Correlated with Peaks of Influenza Virus Activity in Northern Europe during 2010⁻2018

artículo científico publicado en 2019

Medicines prescription patterns in European neonatal units

scientific article published on 17 October 2019

Meropenem vs standard of care for treatment of late onset sepsis in children of less than 90 days of age: study protocol for a randomised controlled trial

artículo científico publicado en 2011

Meropenem vs standard of care for treatment of neonatal late onset sepsis (NeoMero1): A randomised controlled trial

artículo científico publicado en 2020

Molecular epidemiology of Staphylococcus epidermidis in neonatal intensive care units

artículo científico publicado en 2016

Multidrug resistant Pseudomonas aeruginosa in Estonian hospitals

scholarly article by Kaidi Telling et al published 11 October 2018 in BMC Infectious Diseases

New antibiotics for paediatric use: a review of a decade of regulatory trials submitted to the European Medicines Agency from 2000--why aren't we doing better?

artículo científico

Novel activities of safe-in-human broad-spectrum antiviral agents.

artículo científico publicado en 2018

Off label use of prescription medicines in children in outpatient setting in Estonia is common ⬇️

artículo científico publicado el 1 de mayo de 2011

People living with HIV in Estonia: engagement in HIV care in 2013.

artículo científico publicado en 2016

Peripheral blood RNA gene expression profiling in patients with bacterial meningitis

artículo científico publicado en 2013

Pertussis and parapertussis in children and adults with a persistent cough: an observational study

artículo científico publicado en 2017

Pharmacokinetics and pharmacodynamics of oseltamivir in neonates, infants and children

artículo científico

Pharmacokinetics and safety of intravenous voriconazole in children after single- or multiple-dose administration

artículo científico publicado en 2004

Pharmacokinetics of penicillin G in preterm and term neonates

artículo científico publicado en 2018

Pharmacokinetics of penicillin g in very-low-birth-weight neonates

artículo científico publicado en 2007

Pharmacokinetics, safety, and tolerability of voriconazole in immunocompromised children

artículo científico publicado en 2010

Plasma and CSF pharmacokinetics of meropenem in neonates and young infants: results from the NeoMero studies

scholarly article by Eva Germovsek et al published 19 April 2018 in Journal of Antimicrobial Chemotherapy

Plasmid with Colistin Resistance Gene mcr-1 in Extended-Spectrum-β-Lactamase-Producing Escherichia coli Strains Isolated from Pig Slurry in Estonia

artículo científico publicado en 2016

Population pharmacokinetic analysis of voriconazole plasma concentration data from pediatric studies

artículo científico publicado en 2008

Population pharmacokinetic meta-analysis of individual data to design the first randomized efficacy trial of vancomycin in neonates and young infants

artículo científico publicado en 2019

Potentially harmful excipients in neonatal medicines: a pan-European observational study

artículo científico publicado en 2015

Prevalence and genotypes of GBV-C and its associations with HIV infection among persons who inject drugs in Eastern Europe

artículo científico publicado en 2016

Prevalence of drug resistance mutations in HAART patients infected with HIV-1 CRF06_cpx in Estonia

artículo científico publicado en 2015

Product Substitution as a Way Forward in Avoiding Potentially Harmful Excipients in Neonates.

artículo científico publicado en 2016

Rate of CD4 Decline and HIV-RNA Change Following HIV Seroconversion in Men Who Have Sex With Men

article

Risk factors associated with gut and nasopharyngeal colonization by common Gram-negative species and yeasts in neonatal intensive care units patients

artículo científico publicado en 2011

Safety and immunogenicity of a primary course and booster dose of a combined diphtheria, tetanus, acellular pertussis, hepatitis B and inactivated poliovirus vaccine.

artículo científico publicado en 2006

Safety of voriconazole and dose individualization

artículo científico publicado en 2003

Seroprevalence of IgG antibodies to pertussis toxin in children and adolescents in Estonia

artículo científico publicado en 2014

Short versus long infusion of meropenem in very-low-birth-weight neonates

artículo científico publicado en 2012

Stable level of HIV transmitted drug resistance in Estonia despite significant scale-up of antiretroviral therapy

artículo científico publicado en 2019

Standardising neonatal and paediatric antibiotic clinical trial design and conduct: the PENTA-ID network view

artículo científico publicado en 2019

T Cell Distribution in Relation to HIV/HBV/HCV Coinfections and Intravenous Drug Use.

artículo científico publicado en 2016

The concordance of the limiting antigen and the Bio-Rad avidity assays in persons from Estonia infected mainly with HIV-1 CRF06_cpx.

artículo científico publicado en 2019

The development of gut microbiota in critically ill extremely low birth weight infants assessed with 16S rRNA gene based sequencing

artículo científico publicado en 2014

The impact of transient combination antiretroviral treatment in early HIV infection on viral suppression and immunologic response in later treatment

artículo científico publicado en 2015

The role of breast milk in the colonization of neonatal gut and skin with coagulase-negative staphylococci

artículo científico publicado en 2017

Transmitted drug resistance is still low in newly diagnosed human immunodeficiency virus type 1 CRF06_cpx-infected patients in Estonia in 2010

scientific article published on 05 October 2013

Treatment of scedosporiosis with voriconazole: clinical experience with 107 patients

artículo científico publicado en 2008

Treatment option for sepsis in children in the era of antibiotic resistance

artículo científico

Understanding pharmacokinetics/pharmacodynamics in managing neonatal sepsis

artículo científico publicado en 2010

Use of oral fluid to examine the molecular epidemiology of varicella zoster virus in the United Kingdom and continental Europe

artículo científico publicado en 2012

Using incidence assays within the context of the recent infections testing algorithm

artículo científico publicado en 2014

Voriconazole Treatment for Less‐Common, Emerging, or Refractory Fungal Infections ⬇️

artículo científico publicado el 22 de abril de 2003

Voriconazole concentrations in the cerebrospinal fluid and brain tissue of guinea pigs and immunocompromised patients

artículo científico publicado en 2003

Voriconazole for invasive bone aspergillosis: a worldwide experience of 20 cases

artículo científico publicado en 2005

Voriconazole in the treatment of aspergillosis, scedosporiosis and other invasive fungal infections in children

artículo científico publicado en 2002

Lista de obras de Irja Lutsar

A CCL5 Haplotype Is Associated with Low Seropositivity Rate of HCV Infection in People Who Inject Drugs

A highly sensitive method for the simultaneous UHPLC-MS/MS analysis of clonidine, morphine, midazolam and their metabolites in blood plasma using HFIP as the eluent additive

Absence of genotypic drug resistance and presence of several naturally occurring polymorphisms of human immunodeficiency virus-1 CRF06_cpx in treatment-naive patients in Estonia

Acute gastroenteritis hospitalizations after implementation of universal mass vaccination against rotavirus

Age-appropriate formulations including pharmaceutical excipients in neonatal medicines

Ampicillin versus penicillin in the empiric therapy of extremely low-birthweight neonates at risk of early onset sepsis

An optimised dosing regimen versus a standard dosing regimen of vancomycin for the treatment of late onset sepsis due to Gram-positive microorganisms in neonates and infants aged less than 90 days (NeoVanc): study protocol for a randomised controlle

Antibiotic prescription preferences in paediatric outpatient setting in Estonia and Sweden

Antibiotic therapy for pediatric community-acquired pneumonia: do we know when, what and for how long to treat?

Antiretroviral drug resistance and viral tropism in HIV-1 CRF06_cpx infected patients failing antiretroviral (ARV) therapy

Association between HIV-1 tropism and CCR5 human haplotype E in a Caucasian population

Association between TLR3 rs3775291 and resistance to HIV among highly exposed Caucasian intravenous drug users

Association of IFNλ4 rs12979860 polymorphism with the acquisition of HCV and HIV infections among people who inject drugs

Blood loss related to participation in pharmacokinetic study in preterm neonates

CCL3L1 copy number is a strong genetic determinant of HIV seropositivity in Caucasian intravenous drug users

CCR5 haplotypes influence HCV serostatus in Caucasian intravenous drug users

Central European Vaccination Advisory Group (CEVAG) guidance statement on recommendations for the introduction of HPV vaccines

Characteristics of Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae and Contact to Animals in Estonia

Characterization of integrase region polymorphisms in HIV type 1 CRF06_cpx viruses in treatment-naive patients in Estonia

Clinical and pathological findings of fatal 2009-2010 pandemic influenza A (H1N1) infection in Estonia

Clinical parameters predicting failure of empirical antibacterial therapy in early onset neonatal sepsis, identified by classification and regression tree analysis

Clinical trials in neonatal sepsis

Co-infection with hepatitis C virus (HCV) in Estonian intravenous drug users HIV epidemic

Coagulase negative staphylococcal sepsis in neonates: do we need to adapt vancomycin dose or target?

Coagulase-Negative Staphylococci in Human Milk From Mothers of Preterm Compared With Term Neonates

Comment on Pharmacokinetic Studies in Neonates: The Utility of an Opportunistic Sampling Design

Comparison of two alternative study designs in assessment of medicines utilisation in neonates

Correction: Geographic and Temporal Trends in the Molecular Epidemiology and Genetic Mechanisms of Transmitted HIV-1 Drug Resistance: An Individual-Patient- and Sequence-Level Meta-Analysis

Current management of late onset neonatal bacterial sepsis in five European countries

Design and structure of the Estonian HIV Cohort Study (E-HIV).

Development and Evaluation of a Gentamicin Pharmacokinetic Model That Facilitates Opportunistic Gentamicin Therapeutic Drug Monitoring in Neonates and Infants

Differences in T cell distribution and CCR5 expression in HIV-positive and HIV-exposed seronegative persons who inject drugs

Discovery and development of safe-in-man broad-spectrum antiviral agents

DosOpt: A Tool for Personalized Bayesian Dose Adjustment of Vancomycin in Neonates

Drug utilisation pattern and off-label use of medicines in Estonian neonatal units

Dynamics of pertussis toxin IgG after symptomatic pertussis in children and adults

Emerging transmitted drug resistance in treatment-naïve human immunodeficiency virus-1 CRF06_cpx-infected patients in Estonia

Epidemiological characteristics of pertussis in Estonia, Lithuania, Romania, the Czech Republic, Poland and Turkey-1945 to 2005.

Estimated and reported incidence of pertussis in Estonian adults: A seroepidemiological study

Evaluating Safety Reporting in Paediatric Antibiotic Trials, 2000-2016: A Systematic Review and Meta-Analysis

First report of Wohlfahrtiimonas chitiniclastica from soft tissue and bone infection at an unusually high northern latitude

Framework conditions facilitating paediatric clinical research ⬇️

Full-length genome sequences of Estonian HIV-1 CRF06 and Eastern-European subtype A1 recombinant forms

GAPPS (Grading and Assessment of Pharmacokinetic-Pharmacodynamic Studies) a critical appraisal system for antimicrobial PKPD studies - development and application in pediatric antibiotic studies

Genetic Relatedness of Staphylococcus haemolyticus in Gut and Skin of Preterm Neonates and Breast Milk of Their Mothers.

Genetic relatedness of Gram-negative bacteria colonizing gut and skin of neonates and mother's own milk

Genetic relatedness of coagulase-negative Staphylococci from gastrointestinal tract and blood of preterm neonates with late-onset sepsis

Geographic and temporal trends in the molecular epidemiology and genetic mechanisms of transmitted HIV-1 drug resistance: an individual-patient- and sequence-level meta-analysis

Global shortage of neonatal and paediatric antibiotic trials: rapid review

Gut colonization by aerobic microorganisms is associated with route and type of nutrition in premature neonates

HTLV-1/2 is rare among Eastern-European intravenous drug users (IDUs).

Harmonisation in study design and outcomes in paediatric antibiotic clinical trials: a systematic review

High variability in the dosing of commonly used antibiotics revealed by a Europe-wide point prevalence study: implications for research and dissemination

Higher intake of coagulase-negative staphylococci from maternal milk promotes gut colonization with mecA-negative Staphylococcus epidermidis in preterm neonates

Hospitalised neonates in Estonia commonly receive potentially harmful excipients

Human T-lymphotropic virus types 1 and 2 are rare among intravenous drug users in Eastern Europe

Immunologic response to Hib tetanus toxoid conjugated vaccine coadministered with DTPa either mixed or in two separate injections in toddlers not primed with Hib vaccine

Improved outcome in central nervous system aspergillosis, using voriconazole treatment

In vitrosynergy of oxacillin and gentamicin against coagulase-negative staphylococci from blood cultures of neonates with late-onset sepsis

Infections due to Aspergillus terreus: a multicenter retrospective analysis of 83 cases

Influence of interleukin 10 polymorphisms -592 and -1082 to the HIV, HBV and HCV serostatus among intravenous drug users

Laboratory markers to determine clinical significance of coagulase-negative staphylococci in blood cultures.

Low Temperature and Low UV Indexes Correlated with Peaks of Influenza Virus Activity in Northern Europe during 2010⁻2018

Medicines prescription patterns in European neonatal units

Meropenem vs standard of care for treatment of late onset sepsis in children of less than 90 days of age: study protocol for a randomised controlled trial

Meropenem vs standard of care for treatment of neonatal late onset sepsis (NeoMero1): A randomised controlled trial

Molecular epidemiology of Staphylococcus epidermidis in neonatal intensive care units

Multidrug resistant Pseudomonas aeruginosa in Estonian hospitals

New antibiotics for paediatric use: a review of a decade of regulatory trials submitted to the European Medicines Agency from 2000--why aren't we doing better?

Novel activities of safe-in-human broad-spectrum antiviral agents.

Off label use of prescription medicines in children in outpatient setting in Estonia is common ⬇️

People living with HIV in Estonia: engagement in HIV care in 2013.

Peripheral blood RNA gene expression profiling in patients with bacterial meningitis

Pertussis and parapertussis in children and adults with a persistent cough: an observational study

Pharmacokinetics and pharmacodynamics of oseltamivir in neonates, infants and children

Pharmacokinetics and safety of intravenous voriconazole in children after single- or multiple-dose administration

Pharmacokinetics of penicillin G in preterm and term neonates

Pharmacokinetics of penicillin g in very-low-birth-weight neonates

Pharmacokinetics, safety, and tolerability of voriconazole in immunocompromised children