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Lista de obras de Daved H. Fremont

A Gorilla Adenovirus-Based Vaccine against Zika Virus Induces Durable Immunity and Confers Protection in Pregnancy

artículo científico publicado en 2019

A Library of Infectious Hepatitis C Viruses with Engineered Mutations in the E2 Gene Reveals Growth-Adaptive Mutations That Modulate Interactions with Scavenger Receptor Class B Type I.

artículo científico publicado en 2016

A Murine Herpesvirus Closely Related to Ubiquitous Human Herpesviruses Causes T-Cell Depletion.

artículo científico publicado en 2017

A Potently Neutralizing Antibody Protects Mice against SARS-CoV-2 Infection

artículo científico publicado en 2020

A SARS-CoV-2 Infection Model in Mice Demonstrates Protection by Neutralizing Antibodies

scientific article published on 10 June 2020

A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2

artículo científico publicado en 2020

A Structural Explanation for the Antithrombotic Activity of ARC1172, a DNA Aptamer that Binds von Willebrand Factor Domain A1

artículo científico publicado en 2009

A Therapeutic Antibody against West Nile Virus Neutralizes Infection by Blocking Fusion within Endosomes

artículo científico publicado en 2009

A herpesvirus encoded Qa-1 mimic inhibits natural killer cell cytotoxicity through CD94/NKG2A receptor engagement

artículo científico publicado en 2018

A host receptor enables type 1 pilus-mediated pathogenesis of Escherichia coli pyelonephritis

artículo científico publicado en 2021

A molecular understanding of alphavirus entry

artículo científico publicado en 2020

A short N-terminal peptide motif on flavivirus nonstructural protein NS1 modulates cellular targeting and immune recognition

artículo científico publicado en 2010

A single intranasal or intramuscular immunization with chimpanzee adenovirus vectored SARS-CoV-2 vaccine protects against pneumonia in hamsters

scientific article published on 03 December 2020

Accessory protein recruitment motifs in clathrin-mediated endocytosis

artículo científico publicado en 2002

Adjuvanted H5N1 influenza vaccine enhances both cross-reactive memory B cell and strain-specific naive B cell responses in humans

artículo científico publicado en 2020

Affinity-Restricted Memory B Cells Dominate Recall Responses to Heterologous Flaviviruses

scientific article published on 29 September 2020

Altered compensatory cytokine signaling underlies the discrepancy between Flt3-/- and Flt3l-/- mice

artículo científico publicado en 2018

An Evolutionary Insertion in the Mxra8 Receptor-Binding Site Confers Resistance to Alphavirus Infection and Pathogenesis

artículo científico publicado en 2020

An unusual Fc receptor-related protein expressed in human centroblasts

artículo científico publicado en 2002

Antibodies against West Nile Virus Nonstructural Protein NS1 Prevent Lethal Infection through Fc   Receptor-Dependent and -Independent Mechanisms

artículo científico publicado en 2006

Antibodies targeting epitopes on the cell-surface form of NS1 protect against Zika virus infection during pregnancy

artículo científico publicado en 2020

Antibody Recognition and Neutralization Determinants on Domains I and II of West Nile Virus Envelope Protein

artículo científico publicado en 2006

Antibody Recognition of Cell Surface-Associated NS1 Triggers Fc- Receptor-Mediated Phagocytosis and Clearance of West Nile Virus-Infected Cells

artículo científico publicado en 2007

Antigen-specific cytotoxic T lymphocytes protect against lethal West Nile virus encephalitis.

artículo científico publicado en 2007

Basic and translational applications of engineered MHC class I proteins

scientific article published on 09 September 2010

Bile Salts Alter the Mouse Norovirus Capsid Conformation: Possible Implications for Cell Attachment and Immune Evasion

artículo científico publicado en 2019

Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins ⬇️

artículo científico publicado en 2008

Biochemical features of the MHC-related protein 1 consistent with an immunological function

artículo científico publicado en 2003

Broadly Neutralizing Alphavirus Antibodies Bind an Epitope on E2 and Inhibit Entry and Egress

artículo científico publicado en 2015

CD300LF polymorphisms of inbred mouse strains confer resistance to murine norovirus infection in a cell type-dependent manner

scientific article published on 24 June 2020

Capturing a Flavivirus Pre-Fusion Intermediate

artículo científico publicado en 2009

Cellular and Humoral Immunity Protect against Vaginal Zika Virus Infection in Mice

artículo científico publicado en 2018

Cholesterol 25-hydroxylase suppresses SARS-CoV-2 replication by blocking membrane fusion

scholarly article

Cholesterol 25-hydroxylase suppresses SARS-CoV-2 replication by blocking membrane fusion

artículo científico publicado en 2020

Complement Protein C1q Inhibits Antibody-Dependent Enhancement of Flavivirus Infection in an IgG Subclass-Specific Manner

artículo científico publicado en 2007

Complement Protein C1q Reduces the Stoichiometric Threshold for Antibody-Mediated Neutralization of West Nile Virus

artículo científico publicado en 2009

Complex phenotypes in mosquitoes and mice associated with neutralization escape of a Dengue virus type 1 monoclonal antibody

artículo científico publicado en 2012

Correlating RANK ligand/RANK binding kinetics with osteoclast formation and function

artículo científico publicado en 2015

Costimulation through NKG2D enhances murine CD8+ CTL function: similarities and differences between NKG2D and CD28 costimulation

artículo científico publicado en 2005

Cowpox virus employs a two-pronged strategy to outflank MHCI antigen presentation

artículo científico publicado en 2013

Cowpox virus encodes a protein that binds B7.1 and B7.2 and subverts T cell costimulation

artículo científico publicado en 2019

Critical neutralizing fragment of Zika virus EDIII elicits cross-neutralization and protection against divergent Zika viruses

artículo científico publicado en 2018

Cross-priming induces immunodomination in the presence of viral MHC class I inhibition

artículo científico publicado en 2018

Cryo-EM Structure of Chikungunya Virus in Complex with the Mxra8 Receptor

scientific article published on 09 May 2019

Crystal Structure of I-Ak in Complex with a Dominant Epitope of Lysozyme ⬇️

artículo científico publicado el 1 de marzo de 1998

Crystal Structure of the Cowpox Virus-Encoded NKG2D Ligand OMCP

artículo científico publicado en 2013

Crystal Structure of the Japanese Encephalitis Virus Envelope Protein

artículo científico publicado en 2012

Crystal Structure of the West Nile Virus Envelope Glycoprotein

artículo científico publicado en 2006

Crystal structures of two viral peptides in complex with murine MHC class I H-2Kb

artículo científico publicado el 14 de agosto de 1992

Cutting edge: FcR-like 5 on innate B cells is targeted by a poxvirus MHC class I-like immunoevasin

artículo científico publicado en 2010

Cutting edge: murine UL16-binding protein-like transcript 1: a newly described transcript encoding a high-affinity ligand for murine NKG2D.

artículo científico publicado en 2002

Dengue and Zika Virus Cross-Reactive Human Monoclonal Antibodies Protect against Spondweni Virus Infection and Pathogenesis in Mice

artículo científico publicado en 2019

Development of a highly protective combination monoclonal antibody therapy against Chikungunya virus

artículo científico publicado en 2013

Development of a humanized monoclonal antibody with therapeutic potential against West Nile virus

artículo científico publicado en 2005

Discovery of a proteinaceous cellular receptor for a norovirus

artículo científico publicado en 2016

Distinct B cell subsets give rise to antigen-specific antibody responses against SARS-CoV-2

artículo científico publicado en 2020

Disulfide bond engineering to trap peptides in the MHC class I binding groove

artículo científico publicado en 2007

Dual GPCR and GAG mimicry by the M3 chemokine decoy receptor

artículo científico publicado en 2007

Dual engagement regulation of protein interactions with the AP-2 adaptor alpha appendage

artículo científico publicado en 2004

Ebola images emerge from the cave

artículo científico publicado en 2008

Emerging principles for the recognition of peptide antigens by MHC class I molecules

artículo científico publicado el 14 de agosto de 1992

Endogenous MHC-related protein 1 is transiently expressed on the plasma membrane in a conformation that activates mucosal-associated invariant T cells

artículo científico publicado en 2011

Enhanced immune presentation of a single-chain major histocompatibility complex class I molecule engineered to optimize linkage of a C-terminally extended peptide.

artículo científico publicado en 2003

Eukaryotic expression systems for structural studies

artículo científico publicado en 2014

Evidence for MR1 antigen presentation to mucosal-associated invariant T cells

artículo científico publicado en 2005

Evidence for a genetic and physical interaction between nonstructural proteins NS1 and NS4B that modulates replication of West Nile virus

artículo científico publicado en 2012

Functional Heterogeneity and Antimycobacterial Effects of Mouse Mucosal-Associated Invariant T Cells Specific for Riboflavin Metabolites.

artículo científico publicado en 2015

Functional analysis of antibodies against dengue virus type 4 reveals strain-dependent epitope exposure that impacts neutralization and protection

artículo científico publicado en 2013

Genetically linked C-type lectin-related ligands for the NKRP1 family of natural killer cell receptors

artículo científico publicado en 2003

Genotype-specific neutralization and protection by antibodies against dengue virus type 3.

artículo científico publicado en 2010

Health Care Associated Outbreak of SARS CoV2 in a Rural Hospital - Missouri, March 2020

scientific article published on 20 October 2020

Hepatitis C virus epitope exposure and neutralization by antibodies is affected by time and temperature

artículo científico publicado en 2011

Human Antibodies Targeting Influenza B Virus Neuraminidase Active Site Are Broadly Protective

scientific article published on 22 September 2020

Human C-type lectin domain family 4, member C (CLEC4C/BDCA-2/CD303) is a receptor for asialo-galactosyl-oligosaccharides

artículo científico publicado en 2011

Human major histocompatibility complex (MHC) class I molecules with disulfide traps secure disease-related antigenic peptides and exclude competitor peptides

artículo científico publicado en 2008

Hydrogen–deuterium exchange mass spectrometry identifies spatially distinct antibody epitopes on domain III of the Zika virus envelope protein

artículo científico publicado en 2020

Identification and sequencing of a novel rodent gammaherpesvirus that establishes acute and latent infection in laboratory mice

artículo científico publicado en 2011

Identification of somatic JAK1 mutations in patients with acute myeloid leukemia

artículo científico publicado en 2007

Immunoglobulin-like transcript receptors on human dermal CD14+ dendritic cells act as a CD8-antagonist to control cytotoxic T cell priming

artículo científico publicado en 2012

Induction of Epitope-Specific Neutralizing Antibodies against West Nile Virus

artículo científico publicado en 2007

LDLRAD3 is a receptor for Venezuelan equine encephalitis virus

artículo científico publicado en 2020

Levels of Circulating NS1 Impact West Nile Virus Spread to the Brain

artículo científico publicado en 2021

Ligands for murine NKG2D display heterogeneous binding behavior

artículo científico publicado en 2002

MMTV superantigens coerce an unconventional topology between the TCR and MHC class II.

artículo científico publicado en 2014

MR1 antigen presentation to mucosal-associated invariant T cells was highly conserved in evolution

scholarly article

MR1 uses an endocytic pathway to activate mucosal-associated invariant T cells

artículo científico publicado en 2008

Manipulation of receptor oligomerization as a strategy to inhibit signaling by TNF superfamily members

artículo científico publicado en 2014

Mechanism of differential Zika and dengue virus neutralization by a public antibody lineage targeting the DIII lateral ridge

scientific article published on 01 February 2020

Molluscum contagiosum virus MC80 sabotages MHC-I antigen presentation by targeting tapasin for ER-associated degradation

scientific article published on 29 April 2019

Mouse and Human Monoclonal Antibodies Protect against Infection by Multiple Genotypes of Japanese Encephalitis Virus

artículo científico publicado en 2018

Mxra8 is a receptor for multiple arthritogenic alphaviruses

artículo científico publicado en 2018

Myeloid skewing in murine autoimmune arthritis occurs in hematopoietic stem and primitive progenitor cells

artículo científico publicado en 2012

N-domain-dependent nonphosphorylated STAT4 dimers required for cytokine-driven activation

scientific article published on 04 January 2004

Natural Killer Cells Control Tumor Growth by Sensing a Growth Factor.

artículo científico publicado en 2017

Natural killer cell-mediated lysis of dorsal root ganglia neurons via RAE1/NKG2D interactions.

artículo científico publicado en 2003

Neutralizing Antibody and Soluble ACE2 Inhibition of a Replication-Competent VSV-SARS-CoV-2 and a Clinical Isolate of SARS-CoV-2

artículo científico publicado en 2020

Neutralizing Antibody and Soluble ACE2 Inhibition of a Replication-Competent VSV-SARS-CoV-2 and a Clinical Isolate of SARS-CoV-2

scientific article published on 03 July 2020

Neutralizing antibodies against Mayaro virus require Fc effector functions for protective activity

artículo científico publicado en 2019

Neutralizing antibody and soluble ACE2 inhibition of a replication-competent VSV-SARS-CoV-2 and a clinical isolate of SARS-CoV-2

artículo científico publicado en 2020

Neutralizing human antibodies prevent Zika virus replication and fetal disease in mice

artículo científico publicado en 2016

Neutralizing monoclonal antibodies against hepatitis C virus E2 protein bind discontinuous epitopes and inhibit infection at a postattachment step

artículo científico publicado en 2011

Oncogenic potential of the DNA replication licensing protein CDT1

scientific journal article

Optimal therapeutic activity of monoclonal antibodies against chikungunya virus requires Fc-FcγR interaction on monocytes

scientific article published on 01 February 2019

Oxidative refolding from inclusion bodies

artículo científico publicado en 2014

Parallel Evolution of Chemokine Binding by Structurally Related Herpesvirus Decoy Receptors

artículo científico publicado en 2016

Patterns of nonclassical MHC antigen presentation

scientific article published on 01 June 2007

Peptide selection by an MHC H-2Kb class I molecule devoid of the central anchor ("C") pocket ⬇️

artículo científico publicado el 15 de marzo de 1998

Plasmepsins IX and X are essential and druggable mediators of malaria parasite egress and invasion.

artículo científico publicado en 2017

Potent dengue virus neutralization by a therapeutic antibody with low monovalent affinity requires bivalent engagement

artículo científico publicado en 2014

Preparation of stable single-chain trimers engineered with peptide, beta2 microglobulin, and MHC heavy chain

scientific article published on 01 November 2009

Protective antibodies against Eastern equine encephalitis virus bind to epitopes in domains A and B of the E2 glycoprotein

artículo científico publicado en 2018

RANKL Employs Distinct Binding Modes to Engage RANK and the Osteoprotegerin Decoy Receptor

artículo científico publicado en 2012

Recognition of a virus-encoded ligand by a natural killer cell activation receptor

artículo científico publicado en 2002

Recognition of open conformers of classical MHC by chaperones and monoclonal antibodies

artículo científico publicado en 2005

Replication-Competent Vesicular Stomatitis Virus Vaccine Vector Protects against SARS-CoV-2-Mediated Pathogenesis in Mice

artículo científico publicado en 2020

Replication-competent vesicular stomatitis virus vaccine vector protects against SARS-CoV-2-mediated pathogenesis

scientific article published on 10 July 2020

Requisite Chromatin Remodeling for Myeloid and Erythroid Lineage Differentiation from Erythromyeloid Progenitors

scientific article published on 01 November 2020

Rodent herpesvirus Peru encodes a secreted chemokine decoy receptor

artículo científico publicado en 2013

SARS-CoV-2 infection severity is linked to superior humoral immunity against the spike

scientific article published on 13 September 2020

Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist.

artículo científico publicado en 2017

Selective targeting of IL-2 to NKG2D bearing cells for improved immunotherapy

artículo científico publicado en 2016

Somatic mutations and germline sequence variants in the expressed tyrosine kinase genes of patients with de novo acute myeloid leukemia

artículo científico publicado en 2008

Structural Basis of Cytochrome c Presentation by IE k

artículo científico publicado en 2002

Structural Basis of Differential Neutralization of DENV-1 Genotypes by an Antibody that Recognizes a Cryptic Epitope

artículo científico publicado en 2012

Structural Basis of Zika Virus-Specific Antibody Protection

artículo científico publicado en 2016

Structural Conservation and Functional Diversity of the Poxvirus Immune Evasion (PIE) Domain Superfamily

artículo científico publicado en 2015

Structural Engineering of pMHC Reagents for T Cell Vaccines and Diagnostics

artículo científico publicado en 2007

Structural Insights into the Mechanisms of Antibody-Mediated Neutralization of Flavivirus Infection: Implications for Vaccine Development

artículo científico publicado en 2008

Structural Mechanism of ER Retrieval of MHC Class I by Cowpox

artículo científico publicado en 2012

Structural and Biophysical Analysis of BST-2/Tetherin Ectodomains Reveals an Evolutionary Conserved Design to Inhibit Virus Release

artículo científico publicado en 2011

Structural basis for murine norovirus engagement of bile acids and the CD300lf receptor

article published in the Proceedings of the National Academy of Sciences of the United States of America

Structural basis for the preferential recognition of immature flaviviruses by a fusion-loop antibody

artículo científico publicado en 2009

Structural basis for the restoration of TCR recognition of an MHC allelic variant by peptide secondary anchor substitution

artículo científico publicado en 2004

Structural basis of Flavivirus NS1 assembly and antibody recognition

artículo científico publicado en 2014

Structural basis of chemokine sequestration by a herpesvirus decoy receptor

artículo científico publicado en 2002

Structural definition of the F-actin-binding THATCH domain from HIP1R

scientific journal article

Structural definition of the H-2Kd peptide-binding motif

artículo científico publicado en 2006

Structural determinants of chemokine binding by an Ectromelia virus-encoded decoy receptor

artículo científico publicado en 2006

Structural determinants of herpesvirus entry mediator recognition by murine B and T lymphocyte attenuator

artículo científico publicado en 2008

Structure and function analysis of therapeutic monoclonal antibodies against dengue virus type 2.

artículo científico publicado en 2010

Structure and intracellular targeting of the SARS-coronavirus Orf7a accessory protein

artículo científico publicado en 2005

Structure of the St. Louis Encephalitis Virus Postfusion Envelope Trimer

artículo científico publicado en 2013

Structure, expression, and intracellular localization of the SARS-CoV accessory proteins 7a and 7b.

artículo científico publicado en 2006

Subversion of cytokine networks by virally encoded decoy receptors

artículo científico publicado en 2012

T-cell tolerance for variability in an HLA class I-presented influenza A virus epitope

artículo científico publicado en 2009

Target selection for structural genomics of infectious diseases

artículo científico publicado en 2014

Targeting of IL-2 to cytotoxic lymphocytes as an improved method of cytokine-driven immunotherapy

artículo científico publicado en 2017

The Development of Therapeutic Antibodies That Neutralize Homologous and Heterologous Genotypes of Dengue Virus Type 1

artículo científico publicado en 2010

The Fc region of an antibody impacts the neutralization of West Nile viruses in different maturation states

artículo científico publicado en 2013

The Stoichiometry of Antibody-Mediated Neutralization and Enhancement of West Nile Virus Infection

artículo científico publicado en 2007

The chemokine binding protein M3 prevents diabetes induced by multiple low doses of streptozotocin

artículo científico publicado en 2007

The low-density lipoprotein receptor promotes infection of multiple encephalitic alphaviruses

artículo científico publicado en 2024

The mechanism of differential neutralization of dengue serotype 3 strains by monoclonal antibody 8A1.

artículo científico publicado en 2013

The role of mhc polymorphism in anti-microbial resistance

artículo científico publicado en 2004

The stimulatory potency of T cell antigens is influenced by the formation of the immunological synapse

artículo científico publicado en 2007

The structural immunology of antibody protection against West Nile virus

artículo científico publicado en 2008

The unusual dynamics of parasite actin result from isodesmic polymerization

artículo científico publicado en 2013

Type- and Subcomplex-Specific Neutralizing Antibodies against Domain III of Dengue Virus Type 2 Envelope Protein Recognize Adjacent Epitopes

artículo científico publicado en 2007

West Nile virus in complex with the Fab fragment of a neutralizing monoclonal antibody

artículo científico publicado en 2006

West Nile virus nonstructural protein NS1 inhibits complement activation by binding the regulatory protein factor H

artículo científico publicado en 2006

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