Lista de obras - Hidde Ploegh - Dominio Público Uruguay

A CREB3-ARF4 signalling pathway mediates the response to Golgi stress and susceptibility to pathogens

artículo científico publicado en 2013

A European slant on mol biol

artículo científico publicado en 2001

A New MHC Locus That Influences Class I Peptide Presentation ⬇️

artículo científico publicado el 1 de noviembre de 1997

A Structural Element within the HUWE1 HECT Domain Modulates Self-ubiquitination and Substrate Ubiquitination Activities

artículo científico publicado en 2010

A biochemical characterization of feline MHC products: unusually high expression of class II antigens on peripheral blood lymphocytes

artículo científico publicado en 1986

A broad screen for targets of immune complexes decorating arthritic joints highlights deposition of nucleosomes in rheumatoid arthritis

scientific article published on 31 August 2009

A catalytic independent function of the deubiquitinating enzyme USP14 regulates hippocampal synaptic short-term plasticity and vesicle number.

artículo científico publicado en 2013

A catalytically inactive mutant of the deubiquitylase YOD-1 enhances antigen cross-presentation.

artículo científico publicado en 2012

A closer look at proteolysis and MHC-class-II-restricted antigen presentation.

artículo científico publicado en 2002

A conserved Bacteroidetes antigen induces anti-inflammatory intestinal T lymphocytes

artículo científico publicado en 2022

A deubiquitinating activity is conserved in the large tegument protein of the herpesviridae

artículo científico publicado en 2005

A deubiquitinating enzyme encoded by HSV-1 belongs to a family of cysteine proteases that is conserved across the family Herpesviridae

artículo científico publicado en 2005

A feline class II alpha gene with striking similarity to the HLA-DPA pseudogene

artículo científico publicado en 1988

A functional proteomics approach links the ubiquitin-related modifier Urm1 to a tRNA modification pathway

artículo científico publicado en 2008

A functional ubiquitin-specific protease embedded in the large tegument protein (ORF64) of murine gammaherpesvirus 68 is active during the course of infection

artículo científico publicado en 2007

A gammaherpesvirus ubiquitin-specific protease is involved in the establishment of murine gammaherpesvirus 68 infection

artículo científico publicado en 2009

A glycosylated type I membrane protein becomes cytosolic when peptide: N-glycanase is compromised

artículo científico publicado en 2004

A herpesvirus ubiquitin-specific protease is critical for efficient T cell lymphoma formation.

artículo científico publicado en 2007

A human herpesvirus 7 glycoprotein, U21, diverts major histocompatibility complex class I molecules to lysosomes

artículo científico publicado en 2001

A hydrophobic transmembrane segment at the carboxyl terminus of thy-1.

artículo científico publicado en 1985

A lipid-based model for the creation of an escape hatch from the endoplasmic reticulum

artículo científico

A membrane protein required for dislocation of misfolded proteins from the ER

artículo científico publicado en 2004

A microengraving method for rapid selection of single cells producing antigen-specific antibodies

artículo científico publicado en 2006

A molecule's right to choose: how diabetogenic class II MHC products bind peptides

artículo científico publicado en 2005

A monoclonal antibody that causes the heterotrimeric G-protein G(o) to release its beta gamma subunits

artículo científico publicado en 1996

A mouse cytomegalovirus glycoprotein, gp34, forms a complex with folded class I MHC molecules in the ER which is not retained but is transported to the cell surface

artículo científico publicado en 1997

A mouse monoclonal antibody against Alexa Fluor 647.

artículo científico publicado en 2014

A myristoylated pseudosubstrate peptide, a novel protein kinase C inhibitor

scientific article published on 01 January 1993

A nanobody suite for yeast scaffold nucleoporins provides details of the nuclear pore complex structure

artículo científico publicado en 2020

A nanobody that recognizes a 14-residue peptide epitope in the E2 ubiquitin-conjugating enzyme UBC6e modulates its activity

artículo científico publicado en 2019

A new MHC locus that influences class I peptide presentation

scientific article published on 01 October 1999

A new TLR2 agonist promotes cross-presentation by mouse and human antigen presenting cells

artículo científico publicado en 2015

A nomenclature solution to mouse MHC confusion.

artículo científico publicado en 1999

A novel active site-directed probe specific for deubiquitylating enzymes reveals proteasome association of USP14

artículo científico publicado en 2001

A novel immunoadsorption device for removing beta2-microglobulin from whole blood

scientific article published on 01 April 2001

A protease draws first blood

scientific article published in Nature

A proteolytic system that compensates for loss of proteasome function ⬇️

artículo científico publicado el 9 de abril de 1998

A pseudosubstrate peptide inhibits protein kinase C-mediated phosphorylation in permeabilized Rat-1 cells

artículo científico publicado en 1990

A reporter screen in a human haploid cell line identifies CYLD as a constitutive inhibitor of NF-κB.

artículo científico publicado en 2013

A role for N-glycanase in the cytosolic turnover of glycoproteins

artículo científico publicado en 2003

A single domain antibody fragment that recognizes the adaptor ASC defines the role of ASC domains in inflammasome assembly

artículo científico publicado en 2016

A single protease, Apg4B, is specific for the autophagy-related ubiquitin-like proteins GATE-16, MAP1-LC3, GABARAP, and Apg8L

scientific journal article

A soluble, single-chain Kd molecule produced by yeast selects a peptide repertoire indistinguishable from that of cell-surface-associated Kd.

artículo científico publicado en 1993

A straight path to circular proteins

artículo científico publicado en 2009

A subset of HLA-B27 molecules contains peptides much longer than nonamers

artículo científico publicado en 1994

A viral deubiquitylating enzyme restores dislocation of substrates from the endoplasmic reticulum (ER) in semi-intact cells.

artículo científico publicado en 2012

A viral peptide can mimic an endogenous peptide for allorecognition of a major histocompatibility complex class I product ⬇️

artículo científico publicado el 1 de junio de 1992

AID-/-mus-/- mice are agammaglobulinemic and fail to maintain B220-CD138+ plasma cells

artículo científico publicado en 2007

Aberrant expression of HLA class-I antigens in Burkitt lymphoma cells

artículo científico publicado en 1991

Accessory molecules for Toll-like receptors and their function ⬇️

artículo científico publicado el 3 de febrero de 2012

Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis

artículo científico publicado en 2004

Acidic amino acid residues in the juxtamembrane region of the nucleotide-sensing TLRs are important for UNC93B1 binding and signaling

artículo científico publicado en 2013

Activation of human B cells: involvement of surface immunoglobulin as evidenced by two biochemically distinct types of response to Staphylococcus aureus.

artículo científico publicado en 1986

Activation of protein kinase C accelerates internalization of transferrin receptor but not of major histocompatibility complex class I, independent of their phosphorylation status ⬇️

artículo científico publicado el 5 de noviembre de 1992

Activity probe for in vivo profiling of the specificity of proteasome inhibitor bortezomib

artículo científico publicado en 2005

Activity-based ubiquitin-specific protease (USP) profiling of virus-infected and malignant human cells

artículo científico publicado en 2004

Allele and locus-specific differences in cell surface expression and the association of HLA class I heavy chain with beta 2-microglobulin: differential effects of inhibition of glycosylation on class I subunit association

artículo científico publicado en 1988

Allele-specific down-regulation of MHC class I antigens in Burkitt lymphoma lines.

artículo científico publicado en 1989

Allosteric activation of apicomplexan calcium-dependent protein kinases.

artículo científico publicado en 2015

Altered ISGylation drives aberrant macrophage-dependent immune responses during SARS-CoV-2 infection

artículo científico publicado en 2021

Altered natural killer cell repertoire in Tap-1 mutant mice

artículo científico publicado en 1994

Amino acid copolymers that alleviate experimental autoimmune encephalomyelitis in vivo interact with heparan sulfates and glycoprotein 96 in APCs

artículo científico publicado en 2013

An HLA lost mutation may lead to leukemic relapse of recipient type six years after bone marrow transplantation

artículo científico publicado en 1987

An RNA nanoparticle vaccine against Zika virus elicits antibody and CD8+ T cell responses in a mouse model

artículo científico publicado en 2017

An analysis of class I antigens of man and other species by one-dimensional IEF and immunoblotting

scientific article published on 01 January 1986

An evaluation of the significance of amino acid sequence homologies in human histocompatibility antigens (HLA-A and HLA-B) with immunoglobulins and other proteins, using relatively short sequences

artículo científico publicado en 1980

An improved biochemical method for the analysis of HLA-class I antigens. Definition of new HLA-class I subtypes

scientific article published on 01 June 1986

An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration.

artículo científico publicado en 2012

Analysis of human class I antigens by two-dimensional gel electrophoresis. I. Polymorphism, evidence for additional (non-HLA-A, B, C) gene products, and identification of variant HLA-A, B antigens

scientific article published on 01 January 1983

Analysis of protease activity in live antigen-presenting cells shows regulation of the phagosomal proteolytic contents during dendritic cell activation

artículo científico publicado en 2002

Anti-CTLA-4 therapy requires an Fc domain for efficacy

artículo científico publicado en 2018

Antigen presentation and the ubiquitin-proteasome system in host-pathogen interactions

artículo científico publicado en 2006

Antigen presentation subverted: Structure of the human cytomegalovirus protein US2 bound to the class I molecule HLA-A2

artículo científico publicado en 2001

Antigen presentation: immunologists co-opt cell biology

artículo científico publicado en 1996

Antigen presentation: untapped peptides

artículo científico publicado en 1993

Antigen recognition

artículo científico publicado en 1998

Antigen-Specific Induction of Regulatory T Cells In Vivo and In Vitro ⬇️

artículo científico publicado el 1 de enero de 2011

Antigen-specific B-cell receptor sensitizes B cells to infection by influenza virus

artículo científico publicado en 2013

Apicomplexan UCHL3 retains dual specificity for ubiquitin and Nedd8 throughout evolution

Are MHC-bound peptides a nuisance for positive selection?

artículo científico publicado en 1994

Asparagine endopeptidase is not essential for class II MHC antigen presentation but is required for processing of cathepsin L in mice.

artículo científico publicado en 2005

Assembly and intracellular targeting of the betagamma subunits of heterotrimeric G proteins

artículo científico publicado en 1997

Assembly and intracellular transport of major histocompatibility complex molecules ⬇️

artículo científico publicado el 1 de agosto de 1991

Assembly of HLA DR1 molecules translated in vitro: binding of peptide in the endoplasmic reticulum precludes association with invariant chain.

artículo científico publicado en 1994

Association of mouse mammary tumor virus superantigen with MHC class II during biosynthesis

artículo científico publicado en 2001

Association with beta 2-microglobulin controls the expression of transfected human class I genes

artículo científico publicado en 1987

Attachment of Chlamydia trachomatis L2 to host cells requires sulfation.

artículo científico publicado en 2012

Autoantibodies produced at the site of tissue damage provide evidence of humoral autoimmunity in inclusion body myositis

artículo científico publicado en 2012

B-cell receptor signaling in lymphoid malignancies and autoimmunity

artículo científico publicado en 2014

BAT3 Guides Misfolded Glycoproteins Out of the Endoplasmic Reticulum ⬇️

artículo científico publicado el 8 de diciembre de 2011

Behavioral responses of epidermal Langerhans cells in situ to local pathological stimuli.

artículo científico publicado en 2006

Biochemical analysis of variant HLA-B27 antigens

artículo científico publicado en 1983

Biochemical and cellular identification of HLA-Bw44 subtypes

artículo científico publicado en 1984

Biochemical evidence that the DLA-B locus codes for a class II determinant expressed on all canine peripheral blood lymphocytes

artículo científico publicado en 1989

Biosynthesis and assembly of MHC antigens.

scientific article published on December 1990

Biosynthesis and assembly of MHC antigens.

artículo científico publicado en 1990

Biosynthesis and cell surface localization of nonglycosylated human histocompatibility antigens

artículo científico publicado en 1981

Biosynthesis of major histocompatibility complex molecules and generation of T cells in Ii TAP1 double-mutant mice.

artículo científico publicado en 1996

Biosynthesis of murine immunoglobulin D: heterogeneity of glycosylation

scientific article published on 01 October 1982

Bispecific antibody generated with sortase and click chemistry has broad antiinfluenza virus activity

artículo científico publicado en 2014

Bridging B cell and T cell recognition of antigen

artículo científico publicado en 2007

Bruton's Tyrosine Kinase (BTK) and Vav1 contribute to Dectin1-dependent phagocytosis of Candida albicans in macrophages

artículo científico publicado en 2013

CD8(+) T cells from mice transnuclear for a TCR that recognizes a single H-2K(b)-restricted MHV68 epitope derived from gB-ORF8 help control infection

artículo científico publicado en 2012

CD82 controls CpG-dependent TLR9 signaling

artículo científico publicado en 2019

CD8α(+) dendritic cells are the critical source of interleukin-12 that controls acute infection by Toxoplasma gondii tachyzoites ⬇️

artículo científico publicado el 26 de agosto de 2011

CEACAM1 regulates TIM-3-mediated tolerance and exhaustion

scientific journal article

CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance

artículo científico publicado en 2005

Can viruses help us to understand and classify the MHC class I molecules at the maternal-fetal interface?

artículo científico publicado en 2000

Catching proteases in action with microarrays

artículo científico publicado en 2004

Catch‐and‐Release Probes Applied to Semi‐Intact Cells Reveal Ubiquitin‐Specific Protease Expression in Chlamydia trachomatis Infection ⬇️

artículo científico publicado el 18 de enero de 2013

Cathepsin L is essential for onset of autoimmune diabetes in NOD mice

artículo científico publicado en 2005

Cathepsin L: Critical Role in Ii Degradation and CD4 T Cell Selection in the Thymus ⬇️

artículo científico publicado el 17 de abril de 1998

Cathepsin S activity regulates antigen presentation and immunity ⬇️

artículo científico publicado el 1 de junio de 1998

Cathepsin S controls the trafficking and maturation of MHC class II molecules in dendritic cells.

artículo científico publicado en 1999

Cathepsin S regulates class II MHC processing in human CD4+ HLA-DR+ T cells

artículo científico publicado en 2009

Cathepsin S required for normal MHC class II peptide loading and germinal center development

scientific journal article

Cathepsins B and D are dispensable for major histocompatibility complex class II-mediated antigen presentation ⬇️

artículo científico publicado el 14 de abril de 1998

Cell-free synthesis and processing of the heavy and light chains of HLA-DR antigens

artículo científico publicado en 1980

Cell-free translation of the mRNAs for the heavy and light chains of HLA-A and HLA-B antigens

artículo científico publicado en 1979

Cell-specific TLR9 trafficking in primary APCs of transgenic TLR9-GFP mice

artículo científico publicado en 2012

Cellular internalization of cytolethal distending toxin: a new end to a known pathway

artículo científico publicado en 2005

Chaperone AMPylation modulates aggregation and toxicity of neurodegenerative disease-associated polypeptides.

artículo científico publicado en 2018

Characterization and structural studies of the Plasmodium falciparum ubiquitin and Nedd8 hydrolase UCHL3

artículo científico publicado en 2009

Characterization of a G-protein beta-subunit gene from the nematode Caenorhabditis elegans

artículo científico publicado en 1990

Characterization of in vivo expanded OspA-specific human T-cell clones

artículo científico publicado en 2005

Chemical biology: Dressed-up proteins

scientific article published in Nature

Chemical modification of the glucosidase inhibitor 1-deoxynojirimycin. Structure-activity relationships ⬇️

artículo científico publicado el 5 de agosto de 1991

Chemical probes for the rapid detection of Fatty-acylated proteins in Mammalian cells

artículo científico publicado en 2007

Chemistry in living cells: detection of active proteasomes by a two-step labeling strategy

artículo científico publicado en 2003

Chemistry-based functional proteomics reveals novel members of the deubiquitinating enzyme family

artículo científico publicado en 2002

Chemistry-based functional proteomics: mechanism-based activity-profiling tools for ubiquitin and ubiquitin-like specific proteases

artículo científico publicado en 2004

Chemoenzymatic Site-Specific Labeling of Influenza Glycoproteins as a Tool to Observe Virus Budding in Real Time ⬇️

artículo científico publicado el 22 de marzo de 2012

Chlamydia trachomatis-derived deubiquitinating enzymes in mammalian cells during infection

scientific journal article

Cholera toxin activates nonconventional adjuvant pathways that induce protective CD8 T-cell responses after epicutaneous vaccination

artículo científico publicado en 2012

Class I negative CD8 T cells reveal the confounding role of peptide-transfer onto CD8 T cells stimulated with soluble H2-Kb molecules

artículo científico publicado en 2002

Class II MHC peptide loading by the professionals

artículo científico publicado en 2004

Class II MHC self-antigen presentation in human B and T lymphocytes

artículo científico publicado en 2012

Class Ia MHC-deficient BALB/c mice generate CD8+ T cell-mediated protective immunity against Listeria monocytogenes infection

artículo científico publicado en 2003

Cocapture of cognate and bystander antigens can activate autoreactive B cells

artículo científico publicado en 2017

Comparison of amino acid sequences of two human histocompatibility antigens, HLA-A2 and HLA-B7: location of putative alloantigenic sites ⬇️

artículo científico publicado el 1 de septiembre de 1979

Competition by inhibitory oligonucleotides prevents binding of CpG to C‐terminal TLR9 ⬇️

artículo científico publicado el 6 de septiembre de 2011

Complete primary structure of human histocompatibility antigen HLA-B7: evolutionary and functional implications

scientific article published on 01 January 1980

Concanamycin B inhibits the expression of newly-synthesized MHC class II molecules on the cell surface

scientific article published on 01 June 1995

Concurrent detection of secreted products from human lymphocytes by microengraving: cytokines and antigen-reactive antibodies

artículo científico publicado en 2008

Control of cross-presentation during dendritic cell maturation

artículo científico publicado en 2004

Correction: Live Imaging of Cysteine-Cathepsin Activity Reveals Dynamics of Focal Inflammation, Angiogenesis, and Polyp Growth.

artículo científico publicado en 2008

Corrigendum: CEACAM1 regulates TIM-3-mediated tolerance and exhaustion

artículo científico publicado en 2016

Corrigendum: Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining.

artículo científico publicado en 2016

Cotranslational endoplasmic reticulum assembly of FcepsilonRI controls the formation of functional IgE-binding receptors

artículo científico publicado en 2005

Covalent modification of the active site threonine of proteasomal beta subunits and the Escherichia coli homolog HslV by a new class of inhibitors

artículo científico publicado en 1997

Crosses of two independently derived transgenic mice demonstrate functional complementation of the genes encoding heavy (HLA-B27) and light (beta 2-microglobulin) chains of HLA class I antigens

artículo científico publicado en 1987

Crystal Structure and Conformational Change Mechanism of a Bacterial Nramp-Family Divalent Metal Transporter

artículo científico publicado en 2016

Crystal structure of a substrate-engaged SecY protein-translocation channel

artículo científico publicado en 2016

Crystal structure of the boronic acid-based proteasome inhibitor bortezomib in complex with the yeast 20S proteasome

artículo científico publicado en 2006

Cytokines regulate proteolysis in major histocompatibility complex class II-dependent antigen presentation by dendritic cells

artículo científico publicado en 2001

Cytomegaloviruses use multiple mechanisms to elude the host immune response

artículo científico publicado en 1997

DM exchange mechanism

artículo científico publicado en 1995

Deficiency of antigen-presenting cell invariant chain reduces atherosclerosis in mice

artículo científico publicado en 2010

Definition of four HLA-A2 subtypes by CML typing and biochemical analysis

scientific article published on 01 January 1983

Degradation of Mouse Invariant Chain: Roles of Cathepsins S and D and the Influence of Major Histocompatibility Complex Polymorphism ⬇️

artículo científico publicado el 18 de agosto de 1997

Degradation of proteins from the ER of S. cerevisiae requires an intact unfolded protein response pathway

artículo científico publicado en 2000

Dendrimer-RNA nanoparticles generate protective immunity against lethal Ebola, H1N1 influenza, and Toxoplasma gondii challenges with a single dose

artículo científico publicado en 2016

Derlin-2-deficient mice reveal an essential role for protein dislocation in chondrocytes

scientific journal article

Destruction of proteins as a creative force

artículo científico publicado en 1997

Determinants of GBP recruitment to Toxoplasma gondii vacuoles and the parasitic factors that control it

artículo científico publicado en 2011

Determination of attachment sites for N-linked carbohydrate groups of class II histocompatibility alpha-chain and analysis of possible O-linked glycosylation of alpha- and gamma-chains

artículo científico publicado en 1986

Development of an influenza virus protein array using Sortagging technology

artículo científico publicado en 2012

Development of an isotope-coded activity-based probe for the quantitative profiling of cysteine proteases

artículo científico publicado en 2004

Development of intravital intermittent confocal imaging system for studying Langerhans cell turnover.

artículo científico publicado en 2006

Deviant trafficking of I-Ad mutant molecules is reflected in their peptide binding properties

artículo científico publicado en 1999

Diacylglycerol kinase is phosphorylated in vivo upon stimulation of the epidermal growth factor receptor and serine/threonine kinases, including protein kinase C-ε ⬇️

artículo científico publicado el 1 de febrero de 1993

Different types of allospecific CTL clones identified by their ability to recognize peptide loading-defective target cells

artículo científico publicado en 1991

Differential dependence of CD4+CD25+ regulatory and natural killer-like T cells on signals leading to NF-kappaB activation

scholarly article

Differential effects of Usp14 and Uch-L1 on the ubiquitin proteasome system and synaptic activity.

scientific article published on 15 August 2008

Differential priming of CD8 and CD4 T-cells in animal models of autoimmune hepatitis and cholangitis

article

Differential reactivity of residual CD8+ T lymphocytes in TAP1 and beta 2-microglobulin mutant mice

artículo científico publicado en 1995

Differential regulation of effector- and central-memory responses to Toxoplasma gondii Infection by IL-12 revealed by tracking of Tgd057-specific CD8+ T cells

artículo científico publicado en 2010

Direct binding of peptide to empty MHC class I molecules on intact cells and in vitro.

artículo científico publicado en 1990

Discovery of CD8+ T cell epitopes in Chlamydia trachomatis infection through use of caged class I MHC tetramers

artículo científico publicado en 2008

Discovery of antivirals against smallpox

artículo científico publicado en 2004

Dislocation of a type I membrane protein requires interactions between membrane-spanning segments within the lipid bilayer

artículo científico publicado en 2003

Dislocation of type I membrane proteins from the ER to the cytosol is sensitive to changes in redox potential

artículo científico publicado en 1998

Display of Native Antigen on cDC1 That Have Spatial Access to Both T and B Cells Underlies Efficient Humoral Vaccination

artículo científico publicado en 2020

Disruption of Sphingolipid Biosynthesis Blocks Phagocytosis of Candida albicans

artículo científico publicado en 2015

Dissecting Intracellular Proteolysis Using Small Molecule Inhibitors and Molecular Probes

Dissection of the dislocation pathway for type I membrane proteins with a new small molecule inhibitor, eeyarestatin

artículo científico publicado en 2004

Distribution and elimination of the glycosidase inhibitors 1-deoxymannojirimycin and N-methyl-1-deoxynojirimycin in the rat in vivo

artículo científico publicado el 1 de noviembre de 1992

Don Craig Wiley (1944-2001).

artículo científico publicado en 2002

Down-regulation of MHC class I antigen presentation by HCMV; lessons for tumor immunology

artículo científico publicado en 2000

Dual role of ancient ubiquitous protein 1 (AUP1) in lipid droplet accumulation and endoplasmic reticulum (ER) protein quality control

artículo científico publicado en 2011

Durable antitumor responses to CD47 blockade require adaptive immune stimulation

artículo científico publicado en 2016

ERAD components Derlin-1 and Derlin-2 are essential for postnatal brain development and motor function

artículo científico publicado en 2021

Early BCR Events and Antigen Capture, Processing, and Loading on MHC Class II on B Cells

artículo científico publicado en 2014

Early endosomal maturation of MHC class II molecules independently of cysteine proteases and H-2DM.

artículo científico publicado en 2000

Editorial overview

artículo científico publicado en 2009

Editorial overview: Special section: Immunological engineering

artículo científico publicado en 2015

Editorial: Crystal death: it's not always the inflammasome...

artículo científico publicado en 2017

Effect of reduced temperature on glycoprotein (Ig, HLA) processing and transport in lymphoid cells

artículo científico publicado en 1985

Effects of PS-341 on the activity and composition of proteasomes in multiple myeloma cells

artículo científico publicado en 2005

Effects of the glucosidase inhibitors nojirimycin and deoxynojirimycin on the biosynthesis of membrane and secretory glycoproteins ⬇️

artículo científico publicado el 1 de enero de 1983

ElaD, a Deubiquitinating protease expressed by E. coli

artículo científico publicado en 2007

Elimination In Vivo of Developing T Cells by Natural Killer Cells ⬇️

artículo científico publicado el 20 de octubre de 2003

Empty class II major histocompatibility complex created by peptide photolysis establishes the role of DM in peptide association

artículo científico publicado en 2007

End the wasteful tyranny of reviewer experiments ⬇️

artículo científico publicado el 28 de abril de 2011

Engineered erythrocytes covalently linked to antigenic peptides can protect against autoimmune disease

scientific article published on 07 March 2017

Engineered red blood cells as carriers for systemic delivery of a wide array of functional probes

artículo científico publicado en 2014

Engineered red blood cells carrying PCSK9 inhibitors persistently lower LDL and prevent obesity

artículo científico publicado en 2021

Enhanced Cell Capture on Functionalized Graphene Oxide Nanosheets through Oxygen Clustering.

artículo científico publicado en 2017

Enzymatic blockade of the ubiquitin-proteasome pathway

artículo científico publicado en 2011

Enzyme-Mediated Modification of Single-Domain Antibodies for Imaging Modalities with Different Characteristics

artículo científico publicado en 2015

Epithelial-to-Mesenchymal Transition Contributes to Immunosuppression in Breast Carcinomas

artículo científico publicado en 2017

Epithelial-to-mesenchymal transition activates PERK-eIF2α and sensitizes cells to endoplasmic reticulum stress

artículo científico publicado en 2014

Essential role for cathepsin S in MHC class II-associated invariant chain processing and peptide loading

artículo científico publicado en 1996

Evasion of innate cytosolic DNA sensing by a gammaherpesvirus facilitates establishment of latent infection

artículo científico publicado en 2015

Exploiting Nanobodies' Singular Traits

artículo científico publicado en 2018

Exploring cellular biochemistry with nanobodies

artículo científico publicado en 2020

Extended peptide-based inhibitors efficiently target the proteasome and reveal overlapping specificities of the catalytic beta-subunits

artículo científico publicado en 2001

Fluorophore-Conjugated Holliday Junctions for Generating Super-Bright Antibodies and Antibody Fragments

artículo científico publicado en 2015

Free IL-12p40 monomer is a polyfunctional adaptor for generating novel IL-12-like heterodimers extracellularly

artículo científico publicado en 2014

Functional proteomics of the active cysteine protease content in Drosophila S2 cells

artículo científico publicado en 2003

Functionality of major histocompatibility complex class II molecules in mice doubly deficient for invariant chain and H-2M complexes ⬇️

artículo científico publicado el 19 de agosto de 1997

Fungal recognition is mediated by the association of dectin-1 and galectin-3 in macrophages.

artículo científico publicado en 2011

GPR107, a G-protein-coupled receptor essential for intoxication by Pseudomonas aeruginosa exotoxin A, localizes to the Golgi and is cleaved by furin

artículo científico publicado en 2014

Galectin-3 Regulates γ-Herpesvirus Specific CD8 T Cell Immunity

Gene conversion-like mechanisms may generate polymorphism in human class I genes

artículo científico publicado en 1986

Gene expression analysis of B-lymphoma cells resistant and sensitive to bortezomib*

article

Generation of Immunity against Pathogens via Single-Domain Antibody-Antigen Constructs.

artículo científico publicado en 2016

Generation, translocation, and presentation of MHC class I-restricted peptides

artículo científico publicado en 1995

Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation

artículo científico publicado en 2014

Getting the inside out: the transporter associated with antigen processing (TAP) and the presentation of viral antigen

artículo científico publicado en 1995

Global gene disruption in human cells to assign genes to phenotypes by deep sequencing

artículo científico publicado en 2011

Granulin Is a Soluble Cofactor for Toll-like Receptor 9 Signaling ⬇️

artículo científico publicado el 14 de abril de 2011

Graphene Oxide Nanosheets Modified with Single-Domain Antibodies for Rapid and Efficient Capture of Cells.

artículo científico publicado en 2015

HLA-A- and HLA-B-specific monoclonal antibodies reactive with free heavy chains in western blots, in formalin-fixed, paraffin-embedded tissue sections and in cryo-immuno-electron microscopy

artículo científico publicado en 1990

HLA-G and HLA-C at the feto-maternal interface: lessons learned from pathogenic viruses

artículo científico publicado en 1999

HLA-restricted recognition of viral antigens in HLA transgenic mice

artículo científico publicado en 1987

Haploid genetic screens in human cells identify host factors used by pathogens

artículo científico publicado en 2009

Helicobacter pylori cytotoxin-associated gene A (CagA) subverts the apoptosis-stimulating protein of p53 (ASPP2) tumor suppressor pathway of the host

artículo científico publicado en 2011

Hepta-Mutant Staphylococcus aureus Sortase A (SrtA7m) as a Tool for in Vivo Protein Labeling in Caenorhabditis elegans

artículo científico publicado en 2017

Herman Eisen (1918–2014)

artículo científico publicado en 2014

Herpes simplex virus blocks intracellular transport of HLA-G in placentally derived human cells.

artículo científico publicado en 1996

Herpes simplex virus turns off the TAP to evade host immunity

artículo científico publicado en 1995

Herpesvirus evasion of T-cell immunity

Hidde Ploegh: immunologist, journeyman. Interview by Nicole LeBrasseur

artículo científico publicado en 2007

High-molecular-weight protein (pUL48) of human cytomegalovirus is a competent deubiquitinating protease: mutant viruses altered in its active-site cysteine or histidine are viable

artículo científico publicado en 2006

High-resolution one-dimensional isoelectric focusing of mouse MHC class I antigens

scientific article published on 01 January 1990

How MHC class II molecules acquire peptide cargo: biosynthesis and trafficking through the endocytic pathway

artículo científico publicado en 1995

How MHC class II molecules reach the endocytic pathway

artículo científico publicado en 1995

How lamina-associated polypeptide 1 (LAP1) activates Torsin.

artículo científico publicado en 2014

Human cytomegalovirus US2 endoplasmic reticulum-lumenal domain dictates association with major histocompatibility complex class I in a locus-specific manner

artículo científico publicado en 2001

Human cytomegalovirus US3 impairs transport and maturation of major histocompatibility complex class I heavy chains

artículo científico publicado en 1996

Human cytomegalovirus down-regulates HLA class I expression by reducing the stability of class I H chains

artículo científico publicado en 1993

Human cytomegalovirus gene products US2 and US11 differ in their ability to attack major histocompatibility class I heavy chains in dendritic cells

artículo científico publicado en 2002

Human cytomegalovirus open reading frame TRL11/IRL11 encodes an immunoglobulin G Fc-binding protein

artículo científico publicado en 2001

Human cytomegalovirus protein US11 provokes an unfolded protein response that may facilitate the degradation of class I major histocompatibility complex products

artículo científico publicado en 2005

Human histocompatibility antigens

scientific article published on 01 January 1983

HypE-specific nanobodies as tools to modulate HypE-mediated target AMPylation

artículo científico publicado en 2015

Identification by functional proteomics of a deubiquitinating/deNeddylating enzyme in Plasmodium falciparum

artículo científico publicado en 2006

Identification of a Novel CD8 T Cell Epitope Derived from Plasmodium berghei Protective Liver-Stage Antigen

artículo científico publicado en 2018

Identification of host cell factors required for intoxication through use of modified cholera toxin

artículo científico publicado en 2011

Identification of new B27 subtypes (B27C and B27D) prevalent in oriental populations

artículo científico publicado en 1986

Identification of proteins associated with murine cytomegalovirus virions

artículo científico publicado en 2004

IgG1 + ovalbumin-specific B-cell transnuclear mice show class switch recombination in rare allelically included B cells ⬇️

artículo científico publicado el 6 de agosto de 2012

Immune and other responses to viral infections.

artículo científico publicado en 2000

Immune escape by Epstein-Barr virus (EBV) carrying Burkitt's lymphoma: in vitro reconstitution of sensitivity to EBV-specific cytotoxic T cells

artículo científico publicado en 1992

Immune-privileged embryonic Swiss mouse STO and STO cell-derived progenitor cells: major histocompatibility complex and cell differentiation antigen expression patterns resemble those of human embryonic stem cell lines

artículo científico publicado en 2006

Immuno-PET identifies the myeloid compartment as a key contributor to the outcome of the antitumor response under PD-1 blockade

scientific article published on 02 August 2019

Immunochemical analysis of glycosylated and nonglycosylated DLA class I antigens

artículo científico publicado en 1984

Immunology at the millennium: looking forward

artículo científico publicado en 1999

Immunology. Nothing 'gainst time's scythe can make defense...

artículo científico publicado en 2004

Impaired autophagy in the lipid-storage disorder Niemann-Pick type C1 disease

artículo científico publicado en 2013

Improved Antitumor Efficacy of Chimeric Antigen Receptor T Cells that Secrete Single-Domain Antibody Fragments

artículo científico publicado en 2020

Improved GPCR Ligands Based on Genetically Impossible Nanobody-Peptide Fusions

Improved GPCR ligands from nanobody tethering

scientific article published on 29 April 2020

In Vitro Translation and Assembly of a Complete T Cell Receptor–CD3 Complex ⬇️

artículo científico publicado el 4 de agosto de 1997

In vitro AMPylation Assays Using Purified, Recombinant Proteins.

artículo científico publicado en 2017

In vivo control of endosomal architecture by class II-associated invariant chain and cathepsin S

artículo científico publicado en 2005

In vivo detection of antigen-specific CD8+ T cells by immuno-positron emission tomography

scientific article published on 14 September 2020

In vivo discovery of immunotherapy targets in the tumour microenvironment

artículo científico publicado en 2014

Increase in positive selection of CD8+ T cells in TAP1-mutant mice by human beta 2-microglobulin transgene

artículo científico publicado en 1995

Increased resistance to non-MHC-restricted cytotoxicity related to HLA A, B expression. Direct demonstration using beta 2-microglobulin-transfected Daudi cells.

artículo científico publicado en 1988

Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining

artículo científico publicado en 2015

Individual cathepsins degrade immune complexes internalized by antigen-presenting cells via Fcgamma receptors

artículo científico publicado en 2001

Influenza virus changes cell-surface glycoproteins including major histocompatibility complex determinants on lymphocytes

artículo científico publicado en 1989

Inhibition of Major Histocompatibility Complex Class I Antigen Presentation in Pig and Primate Cells by Herpes Simplex Virus Type 1 and 2 ICP47 ⬇️

artículo científico publicado el 1 de junio de 1998

Inhibition of N-linked oligosaccharide trimming does not interfere with surface expression of certain integral membrane proteins ⬇️

artículo científico publicado el 1 de marzo de 1984

Inhibition of N-linked oligosaccharide trimming mannosidases blocks human B cell development

artículo científico publicado en 1986

Inhibition of endosomal proteolytic activity by leupeptin blocks surface expression of MHC class II molecules and their conversion to SDS resistance alpha beta heterodimers in endosomes ⬇️

artículo científico publicado el 1 de febrero de 1992

Inhibitors of oligosaccharide processing

artículo científico publicado en 1985

Intact sphingomyelin biosynthetic pathway is essential for intracellular transport of influenza virus glycoproteins.

artículo científico publicado en 2013

Integration of the ubiquitin-proteasome pathway with a cytosolic oligopeptidase activity

artículo científico publicado en 2000

Intercellular trafficking of the nuclear oncoprotein DEK.

artículo científico publicado en 2013

Interference with HIV-induced syncytium formation and viral infectivity by inhibitors of trimming glucosidase

artículo científico publicado en 1987

Intermediates in the assembly and degradation of class I major histocompatibility complex (MHC) molecules probed with free heavy chain-specific monoclonal antibodies

artículo científico publicado en 1996

Internalization of Influenza Virus and Cell Surface Proteins Monitored by Site-Specific Conjugation of Protease-Sensitive Probes

scientific article published on 26 July 2019

Intestinal colonization by Candida albicans alters inflammatory responses in Bruton's tyrosine kinase-deficient mice

artículo científico publicado en 2014

Intracellular expression of camelid single-domain antibodies specific for influenza virus nucleoprotein uncovers distinct features of its nuclear localization.

artículo científico publicado en 2014

Intracellular interactions of transferrin and its receptor during biosynthesis

artículo científico publicado en 1990

Intracellular targeting of the proteasome

artículo científico publicado en 2000

Intracellular transport of MHC class II molecules

artículo científico publicado en 1992

Introduction of oxygen into the alkyl chain of N-decyl-dNM decreases lipophilicity and results in increased retention of glucose residues on N-linked oligosaccharides

artículo científico publicado en 1994

Invariant chain can bind MHC class II at a site other than the peptide binding groove

artículo científico publicado en 1998

Invariant chain controls the activity of extracellular cathepsin L.

artículo científico publicado en 2002

Involvement of the vacuolar H(+)-ATPases in the secretory pathway of HepG2 cells.

artículo científico publicado en 1993

Isolation and characterization of the intracellular MHC class II compartment.

artículo científico publicado en 1994

Isolation and characterization of three cDNAs coding for Rab proteins from the albumen gland of the mollusc Lymnaea stagnalis

artículo científico publicado en 1993

Isolation, expression, and the primary structure of HLA-Cw1 and HLA-Cw2 genes: evolutionary aspects

artículo científico publicado en 1987

Kaposi's sarcoma-associated herpesvirus K3 utilizes the ubiquitin-proteasome system in routing class major histocompatibility complexes to late endocytic compartments

artículo científico publicado en 2002

LMP2 expression and proteasome activity in NOD mice

Lack of correlation between levels of MHC class I antigen and susceptibility to lysis of small cellular lung carcinoma (SCLC) by natural killer cells

artículo científico publicado en 1989

Lack of expression of HLA-B27 gene in transgenic mouse trophoblast. Conserved genetic pressures underlying extra-embryonic development

artículo científico publicado en 1989

Lessons from viral manipulation of protein disposal pathways

artículo científico publicado en 2002

Lipid modification of proteins through sortase-catalyzed transpeptidation

artículo científico publicado en 2008

Live imaging of cysteine-cathepsin activity reveals dynamics of focal inflammation, angiogenesis, and polyp growth

artículo científico publicado en 2008

Localized CD47 blockade enhances immunotherapy for murine melanoma.

artículo científico publicado en 2017

Logic of the immune system.

artículo científico publicado en 2013

Longitudinal multiparameter assay of lymphocyte interactions from onset by microfluidic cell pairing and culture.

artículo científico publicado en 2016

Loss of Aire-dependent thymic expression of a peripheral tissue antigen renders it a target of autoimmunity

artículo científico publicado en 2007

Loss of Usp14 results in reduced levels of ubiquitin in ataxia mice

artículo científico publicado en 2005

Loss of transporter protein, encoded by the TAP-1 gene, is highly correlated with loss of HLA expression in cervical carcinomas.

artículo científico publicado en 1994

Lysosomal cysteine and aspartic proteases are heterogeneously expressed and act redundantly to initiate human invariant chain degradation

scientific journal article

M13 bacteriophage display framework that allows sortase-mediated modification of surface-accessible phage proteins

artículo científico publicado en 2012

MHC class I antigen processing regulated by cytosolic proteolysis-short cuts that alter peptide generation

artículo científico publicado en 2002

MHC class I expression and CD8+ T cell development in TAP1/β2-microglobulin double mutant mice

artículo científico publicado en 1995

MHC class II dimer of dimers

artículo científico publicado en 1993

MHC products: biosynthesis, intracellular traffic, and "empty" molecules

artículo científico publicado el 1 de enero de 1992

Machinery that guides immunity

artículo científico publicado en 2017

Major histocompatibility antigens: the human (HLA-A, -B, -C) and murine (H-2K, H-2D) class I molecules

scientific article published on 01 May 1981

Major histocompatibility class I presentation of soluble antigen facilitated by Mycobacterium tuberculosis infection

artículo científico publicado en 1996

Major histocompatibility complex (MHC) class I KbDb−/− deficient mice possess functional CD8+ T cells and natural killer cells ⬇️

artículo científico publicado el 13 de octubre de 1998

Major histocompatibility complex class II compartments in human B lymphoblastoid cells are distinct from early endosomes ⬇️

artículo científico publicado el 1 de agosto de 1995

Making and Breaking Peptide Bonds: Protein Engineering Using Sortase ⬇️

artículo científico publicado el 27 de abril de 2011

Mapping functional regions in the lumenal domain of the class II-associated invariant chain

artículo científico publicado en 1994

Mechanism-based probe for the analysis of cathepsin cysteine proteases in living cells

artículo científico publicado en 2006

Mechanism-based proteomics tools based on ubiquitin and ubiquitin-like proteins: crystallography, activity profiling, and protease identification

artículo científico publicado en 2005

Mechanism-based proteomics tools based on ubiquitin and ubiquitin-like proteins: synthesis of active site-directed probes.

artículo científico publicado en 2005

Mechanisms of induction of primary virus-specific cytotoxic T lymphocyte responses

artículo científico publicado el 1 de noviembre de 1992

Mechanisms, biology and inhibitors of deubiquitinating enzymes

artículo científico publicado en 2007

Membrane specializations and endosome maturation in dendritic cells and B cells.

artículo científico publicado en 2004

Membrane-specific, host-derived factors are required for US2- and US11-mediated degradation of major histocompatibility complex class I molecules

artículo científico publicado en 2001

Mice deficient in invariant-chain and MHC class II exhibit a normal mature B2 cell compartment

artículo científico publicado en 2004

Mice lacking H2-M complexes, enigmatic elements of the MHC class II peptide-loading pathway

scientific journal article

Mice lacking the MHC class II-associated invariant chain

scientific journal article

Microbiology. Chemical warfare and mycobacterial defense

artículo científico publicado en 2003

Misfolded major histocompatibility complex class I molecules accumulate in an expanded ER-Golgi intermediate compartment

artículo científico publicado en 1995

Molecular basis of caspase-1 polymerization and its inhibition by a new capping mechanism.

artículo científico publicado en 2016

Molecular characterization of HLA-A, B homologues in owl monkeys and other nonhuman primates

artículo científico publicado en 1980

Molecular cloning of a human histocompatibility antigen cDNA fragment

artículo científico publicado en 1980

Monoclonal Invariant NKT (iNKT) Cell Mice Reveal a Role for Both Tissue of Origin and the TCR in Development of iNKT Functional Subsets.

artículo científico publicado en 2017

Monoclonal antibodies raised against denatured HLA-B locus heavy chains permit biochemical characterization of certain HLA-C locus products

artículo científico publicado en 1986

Monoclonal antibodies that distinguish between free and complexed heterotrimeric G protein beta subunits

scientific article published on 01 February 1997

Monovalent and multivalent ligation of the B cell receptor exhibit differential dependence upon Syk and Src family kinases

artículo científico publicado en 2013

Monovalent engagement of the BCR activates ovalbumin-specific transnuclear B cells

artículo científico publicado en 2014

Monovalent ligation of the B cell receptor induces receptor activation but fails to promote antigen presentation.

artículo científico publicado en 2006

Mouse MHC class I tetramers that are unable to bind to CD8 reveal the need for CD8 engagement in order to activate naive CD8 T cells

artículo científico publicado en 2002

Multiple associated proteins regulate proteasome structure and function

artículo científico publicado en 2002

Multiprotein complexes that link dislocation, ubiquitination, and extraction of misfolded proteins from the endoplasmic reticulum membrane

artículo científico publicado en 2005

Murine B cell response to TLR7 ligands depends on an IFN-beta feedback loop

artículo científico publicado en 2009

Murine female reproductive tract intraepithelial lymphocytes display selection characteristics distinct from both peripheral and other mucosal T cells

scientific article published on 01 October 2001

Murine polyomavirus requires the endoplasmic reticulum protein Derlin-2 to initiate infection

artículo científico publicado en 2006

Myeloid differentiation factor 88 is required for cross-priming in vivo.

artículo científico publicado en 2004

N-linked glycan modification on antigen-presenting cells restores an allospecific cytotoxic T cell response

artículo científico publicado en 1990

N-linked glycosylation does not impair proteasomal degradation but affects class I major histocompatibility complex presentation

artículo científico publicado en 2007

Nanobodies as , non-invasive, imaging agents

Nanobodies in cancer

artículo científico publicado en 2020

Nanobody immunostaining for correlated light and electron microscopy with preservation of ultrastructure

artículo científico publicado en 2018

Nanobody-Antigen Conjugates Elicit HPV-Specific Antitumor Immune Responses

artículo científico publicado en 2018

Nanobody-based CAR T cells that target the tumor microenvironment inhibit the growth of solid tumors in immunocompetent mice

artículo científico publicado en 2019

Negative self-regulation of TLR9 signaling by its N-terminal proteolytic cleavage product

artículo científico publicado en 2014

Neoleukin-2 enhances anti-tumour immunity downstream of peptide vaccination targeted by an anti-MHC class II VHH

scientific article published on 05 February 2020

Neuronal loss and brain atrophy in mice lacking cathepsins B and L

artículo científico publicado en 2002

Nobel Prize: A dark edge to the glory

journal article; published in Nature on 2012-06-20

Non-carrier-mediated uptake of the mannosidase I inhibitor 1-deoxymannojirimycin by K562 erythroleukemic cells

artículo científico publicado en 1989

Noninvasive Imaging of Human Immune Responses in a Human Xenograft Model of Graft-Versus-Host Disease

artículo científico publicado en 2017

Noninvasive imaging of immune responses

artículo científico publicado en 2015

Noninvasive imaging of tumor progression, metastasis, and fibrosis using a nanobody targeting the extracellular matrix

scientific article published on 08 May 2019

Novel mannosidase inhibitor blocking conversion of high mannose to complex oligosaccharides.

artículo científico publicado en 1984

Obituary: Jacques H. van Boom (1937-2004).

artículo científico publicado en 2004

One-Pot Dual Labeling of IgG 1 and Preparation of C-to-C Fusion Proteins Through a Combination of Sortase A and Butelase 1

scientific article published on 21 September 2018

One-dimensional isoelectric focusing of proteins in slab gels

scientific article published on 01 May 2001

One-step enzymatic modification of the cell surface redirects cellular cytotoxicity and parasite tropism

artículo científico publicado en 2014

Optimized fluorescent labeling to identify memory B cells specific for Neisseria meningitidis serogroup B vaccine antigens ex vivo

artículo científico publicado en 2013

Orthogonal labeling of M13 minor capsid proteins with DNA to self-assemble end-to-end multiphage structures.

artículo científico publicado en 2013

PD-L1 is an activation-independent marker of brown adipocytes

artículo científico publicado en 2017

PIKfyve, a class III PI kinase, is the target of the small molecular IL-12/IL-23 inhibitor apilimod and a player in Toll-like receptor signaling

artículo científico publicado en 2013

Parasite stage-specific recognition of endogenous Toxoplasma gondii-derived CD8+ T cell epitopes

artículo científico publicado en 2008

Pathways accessory to proteasomal proteolysis are less efficient in major histocompatibility complex class I antigen production

artículo científico publicado en 2002

Peptide antagonism and T cell receptor interactions with peptide-MHC complexes

artículo científico publicado en 1998

Peptide contributes to the specificity of positive selection of CD8+ T cells in the thymus

artículo científico publicado en 1993

Peptide influences the folding and intracellular transport of free major histocompatibility complex class I heavy chains

artículo científico publicado en 1995

Peptide length and sequence specificity of the mouse TAP1/TAP2 translocator

artículo científico publicado en 1994

Peptide loading of empty major histocompatibility complex molecules on RMA-S cells allows the induction of primary cytotoxic T lymphocyte responses

artículo científico publicado en 1991

Peptide selection by MHC class I molecules ⬇️

artículo científico publicado el 25 de abril de 1991

Peptide translocation by variants of the transporter associated with antigen processing

scientific article published on 01 December 1993

Peptide-induced stabilization and intracellular localization of empty HLA class I complexes ⬇️

artículo científico publicado el 1 de julio de 1992

Peripheral self-reactivity regulates antigen-specific CD8 T-cell responses and cell division under physiological conditions.

artículo científico publicado en 2016

Phenotypic lentivirus screens to identify functional single domain antibodies

artículo científico publicado en 2016

Phosphoproteomic analysis with a solid-phase capture-release-tag approach

artículo científico publicado en 2005

Phosphorylation of IRE1 at S729 regulates RIDD in B cells and antibody production after immunization.

artículo científico publicado en 2018

Podocytes Exhibit a Specialized Protein Quality Control Employing Derlin-2 in Kidney Disease

artículo científico publicado en 2017

Polymorphisms in pockets of major histocompatibility complex class I molecules influence peptide preference

artículo científico publicado en 1993

Polyubiquitination is required for US11-dependent movement of MHC class I heavy chain from endoplasmic reticulum into cytosol

artículo científico publicado en 2001

Positive selection of an MHC class-I restricted TCR in the absence of classical MHC class I molecules

artículo científico publicado en 2001

Posttranscriptional Regulation of Glycoprotein Quality Control in the Endoplasmic Reticulum Is Controlled by the E2 Ub-Conjugating Enzyme UBC6e.

artículo científico publicado en 2016

Predicting the response to CTLA-4 blockade by longitudinal noninvasive monitoring of CD8 T cells.

artículo científico publicado en 2017

Preferred in vivo ubiquitination sites

artículo científico publicado en 2004

Preferred size of peptides that bind to H-2 Kb is sequence dependent

artículo científico publicado el 1 de junio de 1992

Preparation of bispecific antibody-protein adducts by site-specific chemo-enzymatic conjugation

artículo científico publicado en 2018

Preparation of unnatural N-to-N and C-to-C protein fusions ⬇️

artículo científico publicado el 9 de julio de 2012

Production of unnaturally linked chimeric proteins using a combination of sortase-catalyzed transpeptidation and click chemistry

artículo científico

Profiling antibody responses by multiparametric analysis of primary B cells.

artículo científico publicado en 2008

Profiling lymphocyte interactions at the single-cell level by microfluidic cell pairing

artículo científico publicado en 2015

Proteases involved in MHC class II antigen presentation

scientific journal article

Proteasome inhibitors and antigen presentation ⬇️

artículo científico publicado el 1 de enero de 1997

Protection of tissue physicochemical properties using polyfunctional crosslinkers.

artículo científico publicado en 2018

Protein glycosylation

artículo científico publicado en 1990

Protein ligation in living cells using sortase

artículo científico publicado en 2012

Protein quality control in the ER: balancing the ubiquitin checkbook ⬇️

artículo científico publicado el 3 de noviembre de 2011

Protein quality control in the endoplasmic reticulum

artículo científico publicado en 2014

Protein unfolding is not a prerequisite for endoplasmic reticulum-to-cytosol dislocation

artículo científico publicado en 2002

Proteolysis and antigen presentation by MHC class II molecules

scientific journal article

Proteolysis in MHC class II antigen presentation: who's in charge?

artículo científico publicado en 2000

Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9

artículo científico publicado en 2008

Purification, cDNA-cloning and expression of human diacylglycerol kinase

scientific journal article

Putting together an MHC class I molecule

artículo científico publicado en 1993

Qa-2-dependent selection of CD8alpha/alpha T cell receptor alpha/beta(+) cells in murine intestinal intraepithelial lymphocytes

artículo científico publicado en 2000

Qa-2–Dependent Selection of Cd8α/α T Cell Receptor α/β1 Cells in Murine Intestinal Intraepithelial Lymphocytes

artículo científico publicado en 2001

Quality and quantity control at the endoplasmic reticulum

artículo científico publicado en 2010

Quantitative Analysis of Cellular Diacylglycerol Content.

artículo científico publicado en 2014

Rapid capture and labeling of cells on single domain antibodies-functionalized flow cell

artículo científico publicado en 2016

Rapid turnover of unspliced Xbp-1 as a factor that modulates the unfolded protein response

scientific journal article

Ras (proto)oncogene induces N-linked carbohydrate modification: temporal relationship with induction of invasive potential

artículo científico publicado en 1988

Recent advances in sortase-catalyzed ligation methodology.

artículo científico publicado en 2016

Recognition of Class II MHC Peptide Ligands That Contain β-Amino Acids

scientific article published on 07 August 2019

Recruitment of CD63 to Cryptococcus neoformans phagosomes requires acidification

artículo científico publicado en 2006

Recycling glycoproteins do not return to the cis-Golgi

artículo científico publicado en 1988

Regulation of CD1 function and NK1.1(+) T cell selection and maturation by cathepsin S.

artículo científico publicado en 2001

Regulation of monoubiquitinated PCNA by DUB autocleavage

scientific journal article

Release of signal peptide fragments into the cytosol requires cleavage in the transmembrane region by a protease activity that is specifically blocked by a novel cysteine protease inhibitor

artículo científico publicado en 2000

Remodeling of the Tumor Microenvironment by a Chemokine/Anti-PD-L1 Nanobody Fusion Protein

artículo científico publicado en 2019

Repertoire-determining role of peptide in the positive selection of CD8+ T cells

artículo científico publicado en 1993

Requirements for T cell-polarized tubulation of class II+ compartments in dendritic cells

artículo científico publicado en 2003

Retention of epidermal growth factor receptors in the endoplasmic reticulum of adenovirus-infected cells ⬇️

artículo científico publicado el 15 de febrero de 1992

Retrograde transport from the Golgi region to the endoplasmic reticulum is sensitive to GTP gamma S.

artículo científico publicado en 1992

Road to Ruin: Targeting Proteins for Degradation in the Endoplasmic Reticulum ⬇️

artículo científico publicado el 25 de noviembre de 2011

Role for cathepsin F in invariant chain processing and major histocompatibility complex class II peptide loading by macrophages

artículo científico publicado en 2000

Role of the ubiquitin-like protein Urm1 as a noncanonical lysine-directed protein modifier

artículo científico publicado en 2011

SEL1L nucleates a protein complex required for dislocation of misfolded glycoproteins

artículo científico publicado en 2008

SEL1L, the homologue of yeast Hrd3p, is involved in protein dislocation from the mammalian ER.

artículo científico publicado en 2006

Screen for ISG15-crossreactive deubiquitinases

artículo científico publicado en 2007

Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction

artículo científico publicado en 1996

Secreted cathepsin L generates endostatin from collagen XVIII

artículo científico publicado en 2000

Secretion of circular proteins using sortase

artículo científico publicado en 2014

Segregation of MHC class II molecules from MHC class I molecules in the Golgi complex for transport to lysosomal compartments ⬇️

artículo científico publicado el 21 de febrero de 1991

Selective targeting of ligand-dependent and -independent signaling by GPCR conformation-specific anti-US28 intrabodies

artículo científico publicado en 2021

Sequence and structure evolved separately in a ribosomal ubiquitin variant

artículo científico publicado en 2007

Sialylneolacto-N-tetraose c (LSTc)-bearing Liposomal Decoys Capture Influenza A Virus ⬇️

artículo científico publicado el 28 de enero de 2013

Signal peptide cleavage of a type I membrane protein, HCMV US11, is dependent on its membrane anchor

artículo científico publicado en 2001

Signal peptide peptidase is required for dislocation from the endoplasmic reticulum

artículo científico publicado en 2006

Single-chain antibody fragment-based adsorbent for the extracorporeal removal of beta2-microglobulin

artículo científico publicado en 2004

Site-Specific Protein Labeling via Sortase-Mediated Transpeptidation.

artículo científico publicado en 2017

Site-Specific Sequential Protein Labeling Catalyzed by a Single Recombinant Ligase

artículo científico publicado en 2019

Site-specific C-terminal and internal loop labeling of proteins using sortase-mediated reactions

artículo científico publicado en 2013

Site-specific N- and C-terminal labeling of a single polypeptide using sortases of different specificity

artículo científico publicado en 2009

Site-specific N-terminal labeling of proteins using sortase-mediated reactions

artículo científico publicado en 2013

Site-specific chemoenzymatic labeling of aerolysin enables the identification of new aerolysin receptors

artículo científico publicado en 2014

Site-specific protein labeling via sortase-mediated transpeptidation

artículo científico publicado en 2009

Site-specific protein modification using immobilized sortase in batch and continuous-flow systems

artículo científico

Small-Molecule Inhibitors and Probes for Ubiquitin- and Ubiquitin-Like-Specific Proteases

artículo científico publicado en 2005

Soluble class I antigens: a conundrum with no solution?

artículo científico publicado en 1987

Sortagging: a versatile method for protein labeling

artículo científico publicado en 2007

Sortase A as a tool for high-yield histatin cyclization

artículo científico publicado en 2011

Sortase A: A Model for Transpeptidation and Its Biological Applications

artículo científico publicado en 2018

Sortase-catalyzed transformations that improve the properties of cytokines ⬇️

artículo científico publicado el 4 de febrero de 2011

Sortase-mediated modification of αDEC205 affords optimization of antigen presentation and immunization against a set of viral epitopes

artículo científico publicado en 2013

Specific and covalent targeting of conjugating and deconjugating enzymes of ubiquitin-like proteins

artículo científico publicado en 2004

Specific immune responses restored by alteration in carbohydrate chains of surface molecules on antigen-presenting cells

scientific article published on 01 March 1989

Specific role for cathepsin S in the generation of antigenic peptides in vivo

artículo científico publicado en 2002

Stable binding of the herpes simplex virus ICP47 protein to the peptide binding site of TAP

artículo científico publicado en 1996

Stochastic cytokine expression induces mixed T helper cell States

artículo científico publicado en 2013

Structural and functional analysis of human cytomegalovirus US3 protein

artículo científico publicado en 2004

Structural and functional studies on the G(o) protein ⬇️

artículo científico publicado el 5 de marzo de 1993

Structural and sequence homologies between HLA-A and HLA-B antigens and immunoglobulins

artículo científico publicado en 1979

Structural biology. Structural basis for chemokine recognition and activation of a viral G protein-coupled receptor

artículo científico publicado en 2015

Structural heterogeneity of a human melanoma-associated antigen.

artículo científico publicado en 1989

Structural studies of the membrane-associated products of the human major histocompatibility complex

artículo científico publicado en 1980

Structurally Defined αMHC-II Nanobody-Drug Conjugates: A Therapeutic and Imaging System for B-Cell Lymphoma.

artículo científico publicado en 2016

Structure of a herpesvirus-encoded cysteine protease reveals a unique class of deubiquitinating enzymes

artículo científico publicado en 2007

Structure of the ubiquitin hydrolase UCH-L3 complexed with a suicide substrate

artículo científico publicado en 2004

Structures of TorsinA and its disease-mutant complexed with an activator reveal the molecular basis for primary dystonia.

artículo científico publicado en 2016

Substrate binding and sequence preference of the proteasome revealed by active-site-directed affinity probes ⬇️

artículo científico publicado el 1 de junio de 1998

Substrate filtering by the active site crossover loop in UCHL3 revealed by sortagging and gain-of-function mutations

artículo científico publicado en 2008

Substrate specificity of allelic variants of the TAP peptide transporter

scientific article published on 01 December 1994

Subtilase cytotoxin cleaves newly synthesized BiP and blocks antibody secretion in B lymphocytes

artículo científico publicado en 2009

Subunit interactions of the Go protein

artículo científico publicado el 10 de agosto de 1992

Suppression of class I human histocompatibility leukocyte antigen by c-myc is locus specific

artículo científico publicado en 1989

Synthetic peptide libraries in the determination of T cell epitopes and peptide binding specificity of class I molecules

artículo científico publicado el 1 de junio de 1992

T cells induce extended class II MHC compartments in dendritic cells in a Toll-like receptor-dependent manner

artículo científico publicado en 2003

T-cell engagement of dendritic cells rapidly rearranges MHC class II transport.

artículo científico publicado en 2002

TAP1 mutant mice are deficient in antigen presentation, surface class I molecules, and CD4-8+ T cells

artículo científico publicado el 24 de diciembre de 1992

TAP1-dependent peptide translocation in vitro is ATP dependent and peptide selective

artículo científico publicado en 1993

TLRs bent into shape

artículo científico publicado en 2007

Targeted Delivery of Cyclotides via Conjugation to a Nanobody

artículo científico publicado en 2018

Targeted antigen delivery by an anti-class II MHC VHH elicits focused αMUC1(Tn) immunity.

artículo científico publicado en 2017

Targeting cytokine therapy to the pancreatic tumor microenvironment using PD-L1 specific VHHs

artículo científico publicado en 2018

Targeting small molecule drugs to T cells with antibody-directed cell-penetrating gold nanoparticles

artículo científico publicado en 2018

The Angelman Syndrome protein Ube3A regulates synapse development by ubiquitinating arc.

artículo científico publicado en 2010

The Antiviral Mechanism of an Influenza A Virus Nucleoprotein-Specific Single-Domain Antibody Fragment

artículo científico publicado en 2016

The B cell receptor promotes B cell activation and proliferation through a non-ITAM tyrosine in the Igalpha cytoplasmic domain

scientific journal article

The CD8 T-cell response against murine gammaherpesvirus 68 is directed toward a broad repertoire of epitopes from both early and late antigens

artículo científico publicado en 2008

The Caenorhabditis elegans Protein FIC-1 Is an AMPylase That Covalently Modifies Heat-Shock 70 Family Proteins, Translation Elongation Factors and Histones

artículo científico publicado en 2016

The E2 ubiquitin-conjugating enzyme UBE2J1 is required for spermiogenesis in mice

artículo científico publicado en 2014

The ER-lumenal domain of the HHV-7 immunoevasin U21 directs class I MHC molecules to lysosomes.

artículo científico publicado en 2003

The ER-luminal domain of the HCMV glycoprotein US6 inhibits peptide translocation by TAP

artículo científico publicado en 1997

The HCMV gene products US11 and US2 differ in their ability to attack allelic forms of murine major histocompatibility complex (MHC) class I heavy chains

artículo científico publicado en 1997

The HCMV membrane glycoprotein US10 selectively targets HLA-G for degradation

artículo científico publicado en 2010

The SUMO-specific protease SENP5 is required for cell division

artículo científico publicado en 2006

The WD-40 repeat ⬇️

artículo científico publicado el 28 de julio de 1992

The active site of ICP47, a herpes simplex virus-encoded inhibitor of the major histocompatibility complex (MHC)-encoded peptide transporter associated with antigen processing (TAP), maps to the NH2-terminal 35 residues

artículo científico publicado en 1997

The activity of myeloid cell-specific VHH immunotoxins is target-, epitope-, subset- and organ dependent

artículo científico publicado en 2017

The assembly of H2-Kb class I molecules translated in vitro requires oxidized glutathione and peptide

scientific article published on 01 June 1993

The biosynthetic pathway of MHC class II but not class I molecules intersects the endocytic route

artículo científico publicado en 1990

The caspase-like sites of proteasomes, their substrate specificity, new inhibitors and substrates, and allosteric interactions with the trypsin-like sites.

artículo científico publicado en 2003

The cell biology of antigen presentation

artículo científico publicado en 2002

The chaperone BAG6 captures dislocated glycoproteins in the cytosol.

artículo científico publicado en 2014

The co-crystal structure of ubiquitin carboxy-terminal hydrolase L1 (UCHL1) with a tripeptide fluoromethyl ketone (Z-VAE(OMe)-FMK)

artículo científico publicado en 2012

The cytosolic tail of class I MHC heavy chain is required for its dislocation by the human cytomegalovirus US2 and US11 gene products

artículo científico publicado en 1999

The e S-Sence of -SH in the ER ⬇️

artículo científico publicado el 23 de enero de 1998

The effect of anchor residue modifications on the stability of major histocompatibility complex class I-peptide interactions

artículo científico publicado en 1993

The fate of the three subunits of major histocompatibility complex class I molecules ⬇️

artículo científico publicado el 1 de junio de 1992

The human beta 2-microglobulin gene. Primary structure and definition of the transcriptional unit

artículo científico publicado en 1987

The human cytomegalovirus US10 gene product delays trafficking of major histocompatibility complex class I molecules

artículo científico publicado en 2002

The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol

artículo científico publicado en 1996

The human cytomegalovirus US8 glycoprotein binds to major histocompatibility complex class I products

artículo científico publicado en 2002

The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling

scientific journal article

The interest in various immunological subdisciplines waxes and wanes with every new discovery. Preface.

artículo científico publicado en 2014

The known unknowns of antigen processing and presentation.

artículo científico publicado en 2008

The ligand recognized by ELAM-1 on HL60 cells is not carried by N-linked oligosaccharides ⬇️

artículo científico publicado el 1 de diciembre de 1991

The mouse polyubiquitin gene UbC is essential for fetal liver development, cell-cycle progression and stress tolerance

artículo científico publicado en 2007

The otubain YOD1 is a deubiquitinating enzyme that associates with p97 to facilitate protein dislocation from the ER

artículo científico publicado en 2009

The p41 isoform of invariant chain is a chaperone for cathepsin L

artículo científico publicado en 2001

The pathway of US11-dependent degradation of MHC class I heavy chains involves a ubiquitin-conjugated intermediate

artículo científico publicado en 1999

The peptide cargo of class I molecules: not just passive passengers

scientific article published on 01 October 2007

The phenotype of H-2M-deficient mice is dependent on the MHC class II molecules expressed

scientific article published on 01 September 1998

The primary structure of a feline class I gene: striking similarity to HLA-A.

artículo científico publicado en 1989

The protein synthesis inhibitor blasticidin s enters mammalian cells via leucine-rich repeat-containing protein 8D.

artículo científico publicado en 2014

The systemic response to surgery triggers the outgrowth of distant immune-controlled tumors in mouse models of dormancy.

artículo científico publicado en 2018

The tetraspanin CD82 is specifically recruited to fungal and bacterial phagosomes prior to acidification

artículo científico publicado en 2010

The tetraspanin protein CD82 associates with both free HLA class I heavy chain and heterodimeric beta 2-microglobulin complexes

artículo científico publicado en 1997

The transmembrane segment of a tail-anchored protein determines its degradative fate through dislocation from the endoplasmic reticulum

artículo científico publicado en 2010

The ubiquitin-proteasome pathway in thymocyte apoptosis: caspase-dependent processing of the deubiquitinating enzyme USP7 (HAUSP).

artículo científico publicado en 2002

The use of (18)F-2-fluorodeoxyglucose (FDG) to label antibody fragments for immuno-PET of pancreatic cancer

artículo científico publicado en 2015

The α Chain of the T Cell Antigen Receptor Is Degraded in the Cytosol ⬇️

artículo científico publicado el 1 de julio de 1997

The βγ subunits of heterotrimeric G proteins acquire detergent insolubility directly at the plasma membrane ⬇️

artículo científico publicado el 13 de octubre de 1997

Thymic CD4 T cell selection requires attenuation of March8-mediated MHCII turnover in cortical epithelial cells through CD83.

artículo científico publicado en 2016

Thymic Selection and Peripheral Activation of CD8 T Cells by the Same Class I MHC/Peptide Complex

artículo científico publicado en 2004

Tissue-specific and cell surface expression of human major histocompatibility complex class I heavy (HLA-B7) and light (beta 2-microglobulin) chain genes in transgenic mice

artículo científico publicado en 1988

Tissue-specific emergence of regulatory and intraepithelial T cells from a clonal T cell precursor.

artículo científico publicado en 2016

Toxoplasma gondii superinfection and virulence during secondary infection correlate with the exact ROP5/ROP18 allelic combination.

artículo científico publicado en 2015

Trafficking and assembly of MHC molecules: how viruses elude the immune system

artículo científico publicado en 1995

Trained Immunity-Promoting Nanobiologic Therapy Suppresses Tumor Growth and Potentiates Checkpoint Inhibition

scientific article published on 01 October 2020

Translating cell biology in vitro to immunity in vivo.

artículo científico publicado en 2004

Transnuclear CD8 T cells specific for the immunodominant epitope Gra6 lower acute-phase Toxoplasma gondii burden

artículo científico publicado en 2016

Transnuclear TRP1-specific CD8 T cells with high or low affinity TCRs show equivalent antitumor activity

artículo científico publicado en 2013

Transnuclear mice with pre-defined T cell receptor specificities against Toxoplasma gondii obtained via SCNT.

artículo científico publicado en 2010

Transnuclear mice with predefined T cell receptor specificities against Toxoplasma gondii obtained via SCNT.

artículo científico publicado en 2010

Transporters from H-2b, H-2d, H-2s, H-2k, and H-2g7 (NOD/Lt) haplotype translocate similar sets of peptides

artículo científico publicado en 1994

Trophoblast class I major histocompatibility complex (MHC) products are resistant to rapid degradation imposed by the human cytomegalovirus (HCMV) gene products US2 and US11.

artículo científico publicado en 1998

Tubulation of class II MHC compartments is microtubule dependent and involves multiple endolysosomal membrane proteins in primary dendritic cells.

artículo científico publicado en 2007

Turnip yellow mosaic virus protease binds ubiquitin suboptimally to fine-tune its deubiquitinase activity

scientific article published on 30 July 2020

Type I interferon imposes a TSG101/ISG15 checkpoint at the Golgi for glycoprotein trafficking during influenza virus infection.

artículo científico publicado en 2013

UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes

artículo científico publicado en 2008

US2, a Human Cytomegalovirus-encoded Type I Membrane Protein, Contains a Non-cleavable Amino-terminal Signal Peptide

artículo científico publicado en 2002

Ubiquitin C-terminal electrophiles are activity-based probes for identification and mechanistic study of ubiquitin conjugating machinery

artículo científico publicado en 2009

Ubiquitin--conserved protein or selfish gene?

artículo científico publicado en 2005

Ubiquitin-Like Proteins ⬇️

artículo científico publicado el 9 de marzo de 2012

Ubiquitin-dependent control of class II MHC localization is dispensable for antigen presentation and antibody production.

artículo científico publicado en 2011

Ubiquitination, ubiquitin-like modifiers, and deubiquitination in viral infection

scientific article published on June 2009

Ubiquitinylation of the cytosolic domain of a type I membrane protein is not required to initiate its dislocation from the endoplasmic reticulum

artículo científico publicado en 2003

Uncoating ATPase Hsc70 is recruited by invariant chain and controls the size of endocytic compartments

artículo científico publicado en 2002

Unrestrained AMPylation targets cytosolic chaperones and activates the heat shock response

artículo científico publicado en 2016

Upregulation of the CLIP self peptide on mature dendritic cells antagonizes T helper type 1 polarization

artículo científico publicado en 2004

Use of HLA loss mutants to analyse the structure of the human major histocompatibility complex

artículo científico publicado en 1982

Using a small molecule inhibitor of peptide: N-glycanase to probe its role in glycoprotein turnover.

artículo científico publicado en 2004

Usp12 stabilizes the T-cell receptor complex at the cell surface during signaling

scientific journal article

Uvomorulin: a nonintegral membrane protein of early mouse embryo

artículo científico publicado en 1983

Varicella-zoster virus retains major histocompatibility complex class I proteins in the Golgi compartment of infected cells

artículo científico publicado en 2001

Vesicular stomatitis virus N protein-specific single-domain antibody fragments inhibit replication.

artículo científico publicado en 2017

Viral GPCR US28 can signal in response to chemokine agonists of nearly unlimited structural degeneracy.

artículo científico publicado en 2018

Viral Strategies of Immune Evasion ⬇️

artículo científico publicado el 10 de abril de 1998

Viral immune evasion strategies and the underlying cell biology

artículo científico publicado en 2001

Viral immunoevasive strategies and trophoblast class I major histocompatibility complex antigens

artículo científico publicado en 1999

Viral interference with B7-1 costimulation: a new role for murine cytomegalovirus fc receptor-1.

artículo científico publicado en 2006

Viral modulation of antigen presentation: manipulation of cellular targets in the ER and beyond

artículo científico publicado en 2005

Viral subversion of the immune system

artículo científico publicado en 2000

Virus subversion of immunity: a structural perspective

artículo científico publicado en 2001

Viruses use stealth technology to escape from the host immune system

artículo científico publicado en 1997

Visualization of the ER-to-cytosol dislocation reaction of a type I membrane protein

artículo científico publicado en 2002

Why certain antibodies cross-react with HLA-A and HLA-G: epitope mapping of two common MHC class I reagents.

artículo científico publicado en 1998

XBP-1 regulates signal transduction, transcription factors and bone marrow colonization in B cells

artículo científico publicado en 2009

XBP-1 specifically promotes IgM synthesis and secretion, but is dispensable for degradation of glycoproteins in primary B cells

artículo científico publicado en 2005

XBP-1-deficient plasmablasts show normal protein folding but altered glycosylation and lipid synthesis.

artículo científico publicado en 2009

Yeast N-glycanase distinguishes between native and non-native glycoproteins

artículo científico publicado en 2004

Zinc-finger protein A20, a regulator of inflammation and cell survival, has de-ubiquitinating activity

artículo científico publicado en 2004

Zwitterionic polysaccharides stimulate T cells by MHC class II-dependent interactions

artículo científico publicado en 2002

rAMPing Up Stress Signaling: Protein AMPylation in Metazoans.

artículo científico publicado en 2017

tRNA thiolation links translation to stress responses in Saccharomyces cerevisiae

artículo científico publicado en 2014

z-VAD-fmk inhibits peptide:N-glycanase and may result in ER stress

artículo científico publicado en 2006

Lista de obras de Hidde Ploegh

A CREB3-ARF4 signalling pathway mediates the response to Golgi stress and susceptibility to pathogens

A European slant on mol biol

A New MHC Locus That Influences Class I Peptide Presentation ⬇️

A Structural Element within the HUWE1 HECT Domain Modulates Self-ubiquitination and Substrate Ubiquitination Activities

A biochemical characterization of feline MHC products: unusually high expression of class II antigens on peripheral blood lymphocytes

A broad screen for targets of immune complexes decorating arthritic joints highlights deposition of nucleosomes in rheumatoid arthritis

A catalytic independent function of the deubiquitinating enzyme USP14 regulates hippocampal synaptic short-term plasticity and vesicle number.

A catalytically inactive mutant of the deubiquitylase YOD-1 enhances antigen cross-presentation.

A closer look at proteolysis and MHC-class-II-restricted antigen presentation.

A conserved Bacteroidetes antigen induces anti-inflammatory intestinal T lymphocytes

A deubiquitinating activity is conserved in the large tegument protein of the herpesviridae

A deubiquitinating enzyme encoded by HSV-1 belongs to a family of cysteine proteases that is conserved across the family Herpesviridae

A feline class II alpha gene with striking similarity to the HLA-DPA pseudogene

A functional proteomics approach links the ubiquitin-related modifier Urm1 to a tRNA modification pathway

A functional ubiquitin-specific protease embedded in the large tegument protein (ORF64) of murine gammaherpesvirus 68 is active during the course of infection

A gammaherpesvirus ubiquitin-specific protease is involved in the establishment of murine gammaherpesvirus 68 infection

A glycosylated type I membrane protein becomes cytosolic when peptide: N-glycanase is compromised

A herpesvirus ubiquitin-specific protease is critical for efficient T cell lymphoma formation.

A human herpesvirus 7 glycoprotein, U21, diverts major histocompatibility complex class I molecules to lysosomes

A hydrophobic transmembrane segment at the carboxyl terminus of thy-1.

A lipid-based model for the creation of an escape hatch from the endoplasmic reticulum

A membrane protein required for dislocation of misfolded proteins from the ER

A microengraving method for rapid selection of single cells producing antigen-specific antibodies

A molecule's right to choose: how diabetogenic class II MHC products bind peptides

A monoclonal antibody that causes the heterotrimeric G-protein G(o) to release its beta gamma subunits

A mouse cytomegalovirus glycoprotein, gp34, forms a complex with folded class I MHC molecules in the ER which is not retained but is transported to the cell surface

A mouse monoclonal antibody against Alexa Fluor 647.

A myristoylated pseudosubstrate peptide, a novel protein kinase C inhibitor

A nanobody suite for yeast scaffold nucleoporins provides details of the nuclear pore complex structure

A nanobody that recognizes a 14-residue peptide epitope in the E2 ubiquitin-conjugating enzyme UBC6e modulates its activity

A new MHC locus that influences class I peptide presentation

A new TLR2 agonist promotes cross-presentation by mouse and human antigen presenting cells

A nomenclature solution to mouse MHC confusion.

A novel active site-directed probe specific for deubiquitylating enzymes reveals proteasome association of USP14

A novel immunoadsorption device for removing beta2-microglobulin from whole blood

A protease draws first blood

A proteolytic system that compensates for loss of proteasome function ⬇️

A pseudosubstrate peptide inhibits protein kinase C-mediated phosphorylation in permeabilized Rat-1 cells

A reporter screen in a human haploid cell line identifies CYLD as a constitutive inhibitor of NF-κB.

A role for N-glycanase in the cytosolic turnover of glycoproteins

A single domain antibody fragment that recognizes the adaptor ASC defines the role of ASC domains in inflammasome assembly

A single protease, Apg4B, is specific for the autophagy-related ubiquitin-like proteins GATE-16, MAP1-LC3, GABARAP, and Apg8L

A soluble, single-chain Kd molecule produced by yeast selects a peptide repertoire indistinguishable from that of cell-surface-associated Kd.

A straight path to circular proteins

A subset of HLA-B27 molecules contains peptides much longer than nonamers

A viral deubiquitylating enzyme restores dislocation of substrates from the endoplasmic reticulum (ER) in semi-intact cells.

A viral peptide can mimic an endogenous peptide for allorecognition of a major histocompatibility complex class I product ⬇️

AID-/-mus-/- mice are agammaglobulinemic and fail to maintain B220-CD138+ plasma cells

Aberrant expression of HLA class-I antigens in Burkitt lymphoma cells

Accessory molecules for Toll-like receptors and their function ⬇️

Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis

Acidic amino acid residues in the juxtamembrane region of the nucleotide-sensing TLRs are important for UNC93B1 binding and signaling

Activation of human B cells: involvement of surface immunoglobulin as evidenced by two biochemically distinct types of response to Staphylococcus aureus.

Activation of protein kinase C accelerates internalization of transferrin receptor but not of major histocompatibility complex class I, independent of their phosphorylation status ⬇️

Activity probe for in vivo profiling of the specificity of proteasome inhibitor bortezomib

Activity-based ubiquitin-specific protease (USP) profiling of virus-infected and malignant human cells

Allele and locus-specific differences in cell surface expression and the association of HLA class I heavy chain with beta 2-microglobulin: differential effects of inhibition of glycosylation on class I subunit association

Allele-specific down-regulation of MHC class I antigens in Burkitt lymphoma lines.

Allosteric activation of apicomplexan calcium-dependent protein kinases.

Altered ISGylation drives aberrant macrophage-dependent immune responses during SARS-CoV-2 infection

Altered natural killer cell repertoire in Tap-1 mutant mice

Amino acid copolymers that alleviate experimental autoimmune encephalomyelitis in vivo interact with heparan sulfates and glycoprotein 96 in APCs

An HLA lost mutation may lead to leukemic relapse of recipient type six years after bone marrow transplantation

An RNA nanoparticle vaccine against Zika virus elicits antibody and CD8+ T cell responses in a mouse model

An analysis of class I antigens of man and other species by one-dimensional IEF and immunoblotting

An evaluation of the significance of amino acid sequence homologies in human histocompatibility antigens (HLA-A and HLA-B) with immunoglobulins and other proteins, using relatively short sequences

An improved biochemical method for the analysis of HLA-class I antigens. Definition of new HLA-class I subtypes

An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration.

Analysis of human class I antigens by two-dimensional gel electrophoresis. I. Polymorphism, evidence for additional (non-HLA-A, B, C) gene products, and identification of variant HLA-A, B antigens

Analysis of protease activity in live antigen-presenting cells shows regulation of the phagosomal proteolytic contents during dendritic cell activation

Anti-CTLA-4 therapy requires an Fc domain for efficacy

Antigen presentation and the ubiquitin-proteasome system in host-pathogen interactions

Antigen presentation subverted: Structure of the human cytomegalovirus protein US2 bound to the class I molecule HLA-A2

Antigen presentation: immunologists co-opt cell biology

Antigen presentation: untapped peptides

Antigen recognition

Antigen-Specific Induction of Regulatory T Cells In Vivo and In Vitro ⬇️

Antigen-specific B-cell receptor sensitizes B cells to infection by influenza virus

Apicomplexan UCHL3 retains dual specificity for ubiquitin and Nedd8 throughout evolution