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(-)-Epigallocatechin-3-gallate prevents lipopolysaccharide-induced elevation of beta-amyloid generation and memory deficiency

artículo científico publicado en 2008

15,16-dihydrotanshinone I, a major component from Salvia miltiorrhiza Bunge (Dansham), inhibits rabbit platelet aggregation by suppressing intracellular calcium mobilization

artículo científico publicado en 2008

4-O-Methylhonokiol attenuates memory impairment in presenilin 2 mutant mice through reduction of oxidative damage and inactivation of astrocytes and the ERK pathway

artículo científico publicado en 2010

4-O-methylhonokiol attenuated memory impairment through modulation of oxidative damage of enzymes involving amyloid-β generation and accumulation in a mouse model of Alzheimer's disease

artículo científico publicado en 2011

Activation of p38 mitogen-activated protein kinase and activator protein-1 during the promotion of neurite extension of PC-12 cells by 15-deoxy-delta12,14-prostaglandin J2.

artículo científico publicado en 2003

Altered de novo sphingolipid biosynthesis is involved in the serum deprivation-induced cell death in LLC-PK1 cells

artículo científico publicado en 2004

An antithrombotic agent, NQ301, inhibits thromboxane A2 receptor and synthase activity in rabbit platelets

artículo científico publicado en 2005

Anti-Inflammatory Effect of the Oligomeric Stilbene α-Viniferin and its Mode of the Action through Inhibition of Cyclooxygenase-2 and Inducible Nitric Oxide Synthase

artículo científico publicado el 1 de agosto de 2003

Anti-oxidative and photo-protective effects of coumarins isolated from Fraxinus chinensis

artículo científico

Anti-platelet activity of KR-32560, a novel sodium/hydrogen exchanger-1 inhibitor

artículo científico publicado en 2006

Anti-platelet activity of diacetylated obovatol through regulating cyclooxygenase and lipoxygenase activities

artículo científico publicado en 2012

Anti-tumor metastatic activity of beta-glucan purified from mutated Saccharomyces cerevisiae

artículo científico

Antioxidants and inhibitor of matrix metalloproteinase-1 expression from leaves of Zostera marina L.

artículo científico publicado en 2004

Antioxidative and acute anti-inflammatory effects of Campsis grandiflora flower

artículo científico publicado en 2005

Antioxidative and acute antiinflammatory effects of Torreya grandis

scientific article published on 15 May 2006

Antiplatelet Activity of Obovatol, a Biphenolic Component of Magnolia Obovata, in Rat Arterial Thrombosis and Rabbit Platelet Aggregation

artículo científico publicado el 21 de abril de 2011

Antiplatelet action of indirubin-3'-monoxime through suppression of glycoprotein VI-mediated signal transduction: a possible role for ERK signaling in platelets

artículo científico publicado en 2014

Antiplatelet activity of J78 (2-Chloro-3-[2'-bromo, 4'-fluoro-phenyl]-amino-8-hydroxy-1,4-naphthoquinone), an antithrombotic agent, is mediated by thromboxane (TX) A2 receptor blockade with TXA2 synthase inhibition and suppression of cytosolic Ca2+

artículo científico publicado en 2004

Antiplatelet activity of [5-(2-methoxy-5-chlorophenyl)furan-2-ylcarbonyl]guanidine (KR-32570), a novel sodium/hydrogen exchanger-1 and its mechanism of action

artículo científico publicado en 2006

Antiplatelet activity of beta-carboline alkaloids from Perganum harmala: a possible mechanism through inhibiting PLCgamma2 phosphorylation

artículo científico publicado en 2009

Antiplatelet activity of carnosic acid, a phenolic diterpene from Rosmarinus officinalis

artículo científico publicado en 2007

Antiplatelet activity of carnosol is mediated by the inhibition of TXA2 receptor and cytosolic calcium mobilization

artículo científico publicado en 2006

Antiplatelet activity of epigallocatechin gallate is mediated by the inhibition of PLCgamma2 phosphorylation, elevation of PGD2 production, and maintaining calcium-ATPase activity

artículo científico publicado en 2008

Antiplatelet activity of hesperetin, a bioflavonoid, is mainly mediated by inhibition of PLC-gamma2 phosphorylation and cyclooxygenase-1 activity

artículo científico publicado en 2006

Antiplatelet and antithrombotic activities of CP201, a newly synthesized 1,4-naphthoquinone derivative

artículo científico publicado en 2004

Antiplatelet and antithrombotic activities of Korean Red Ginseng

artículo científico publicado en 2006

Antiplatelet effect of NQ12: a possible mechanism through the arachidonic acid cascade

artículo científico publicado en 2007

Antiplatelet effect of green tea catechins: a possible mechanism through arachidonic acid pathway

artículo científico publicado en 2004

Antiproliferative action of cudraflavone B, isolated from Cudrania tricuspidata, through the downregulation of pRb phosphorylation in aortic smooth muscle cell proliferation signaling

artículo científico publicado en 2009

Antiproliferative activity of NQ304, a synthetic 1,4-naphthoquinone, is mediated via the suppressions of the PI3K/Akt and ERK1/2 signaling pathways in PDGF-BB-stimulated vascular smooth muscle cells

artículo científico publicado en 2006

Antithrombotic and antiplatelet activities of Korean red ginseng extract

artículo científico publicado en 2007

Antithrombotic and antiplatelet activities of fenofibrate, a lipid-lowering drug

artículo científico publicado en 2009

BMS-191095, a cardioselective mitochondrial K(ATP) opener, inhibits human platelet aggregation by opening mitochondrial K(ATP) channels

artículo científico publicado en 2005

Camptothecin inhibits platelet-derived growth factor-BB-induced proliferation of rat aortic vascular smooth muscle cells through inhibition of PI3K/Akt signaling pathway

artículo científico publicado el 14 de enero de 2013

Cardioprotective effects of [5-(2-methyl-5-fluorophenyl)furan-2-ylcarbonyl]guanidine (KR-32568) in an anesthetized rat model of ischemia and reperfusion heart injury

artículo científico publicado en 2005

Ceramide 1-phosphate induces neointimal formation via cell proliferation and cell cycle progression upstream of ERK1/2 in vascular smooth muscle cells

artículo científico publicado el 20 de mayo de 2011

Clitocybin A, a Novel Isoindolinone, From the Mushroom Clitocybe aurantiaca, Inhibits Cell Proliferation Through G1 Phase Arrest by Regulating the PI3K/Akt Cascade in Vascular Smooth Muscle Cells

artículo científico publicado el 1 de enero de 2012

Clitocybin B inhibits rat aortic smooth muscle cell proliferation through suppressing PDGF-Rβ phosphorylation

artículo científico publicado el 3 de diciembre de 2011

Combination of ginsenoside Rg3 with docetaxel enhances the susceptibility of prostate cancer cells via inhibition of NF-kappaB.

artículo científico publicado en 2010

Compound K, an intestinal metabolite of ginsenosides, inhibits PDGF-BB-induced VSMC proliferation and migration through G1 arrest and attenuates neointimal hyperplasia after arterial injury

artículo científico publicado en 2013

Concise synthesis of Obovatol: Chemoselective ortho-bromination of phenol and survey of Cu-catalyzed diaryl ether couplings

artículo científico publicado en 2008

Corynoxeine isolated from the hook of Uncaria rhynchophylla inhibits rat aortic vascular smooth muscle cell proliferation through the blocking of extracellular signal regulated kinase 1/2 phosphorylation.

artículo científico publicado en 2008

Cudraflavanone A, a flavonoid isolated from the root bark of Cudrania tricuspidata, inhibits vascular smooth muscle cell growth via an Akt-dependent pathway

artículo científico publicado en 2007

Cudratricusxanthone A isolated from the root bark of Cudrania tricuspidata inhibits the proliferation of vascular smooth muscle cells through the suppression of PDGF-receptor beta tyrosine kinase

artículo científico publicado en 2007

Cyclopeptide alkaloid fraction from Zizyphi Spinosi Semen enhances pentobarbital-induced sleeping behaviors

artículo científico publicado en 2008

Development and diagnostic application/evaluation of pandemic (H1N1) 2009 influenza virus‐specific monoclonal antibodies

artículo científico publicado el 1 de junio de 2012

Distribution of organochlorines and PCB congeners in Korean human tissues

artículo científico publicado en 2005

Echinacea purpurea root extract enhances the adipocyte differentiation of 3T3-L1 cells

artículo científico publicado en 2013

Effects of KTJ740, a novel antithrombotic agent, on platelet-derived growth factor-induced rat aortic smooth muscle cell proliferation and cell cycle progression

scientific article published on 01 May 2007

Effects of [5-(2-methoxy-5-fluorophenyl)furan-2-ylcarbonyl]guanidine (KR-32560), a novel sodium/hydrogen exchanger-1 inhibitor, on myocardial infarct size and ventricular arrhythmias in a rat model of ischemia/reperfusion heart injury

artículo científico publicado en 2005

Effects of apigenin on the serum- and platelet derived growth factor-BB-induced proliferation of rat aortic vascular smooth muscle cells

artículo científico publicado en 2002

Elevation of sphingoid base 1-phosphate as a potential contributor to hepatotoxicity in fumonisin B1-exposed mice

artículo científico publicado en 2007

Endogenous sphingolipid metabolites related to the growth in Sphingomonas chungbukensis

artículo científico

Enhanced menadione cytotoxicity in platelets isolated from streptozotocin-induced diabetic rats

artículo científico

Enhanced release of sphingosine-1-phosphate from hypercholesterolemic platelets: role in development of hypercholesterolemic atherosclerosis

artículo científico publicado en 2008

Epigallocatechin-3-Gallate Inhibits Basic Fibroblast Growth Factor–Induced Intracellular Signaling Transduction Pathway in Rat Aortic Smooth Muscle Cells

artículo científico publicado el 1 de febrero de 2002

Epigallocatechin-3-gallate prevents systemic inflammation-induced memory deficiency and amyloidogenesis via its anti-neuroinflammatory properties

artículo científico publicado en 2012

Epothilone B inhibits neointimal formation after rat carotid injury through the regulation of cell cycle-related proteins

artículo científico publicado en 2007

Epothilone D, a microtubule-stabilizing compound, inhibits neointimal hyperplasia after rat carotid artery injury by cell cycle arrest via regulation of G1-checkpoint proteins

scientific journal article

Ethanol Extract of Magnolia officinalis Prevents Lipopolysaccharide‐Induced Memory Deficiency via Its Antineuroinflammatory and Antiamyloidogenic Effects

artículo científico publicado el 25 de mayo de 2012

Genistein inhibits rat aortic smooth muscle cell proliferation through the induction of p27kip1

scientific journal article

Green tea (-)-epigallocatechin-3-gallate inhibits beta-amyloid-induced cognitive dysfunction through modification of secretase activity via inhibition of ERK and NF-kappaB pathways in mice

artículo científico publicado en 2009

Green tomato extract attenuates high-fat-diet-induced obesity through activation of the AMPK pathway in C57BL/6 mice

artículo científico publicado el 10 de septiembre de 2012

Hesperetin, a bioflavonoid, inhibits rat aortic vascular smooth muscle cells proliferation by arresting cell cycle

scientific journal article

Hinokitiol inhibits cell growth through induction of S-phase arrest and apoptosis in human colon cancer cells and suppresses tumor growth in a mouse xenograft experiment

artículo científico publicado en 2013

IL‐32γ enhances TNF‐α‐induced cell death in colon cancer

artículo científico publicado el 19 de diciembre de 2012

Increase of collagen synthesis by obovatol through stimulation of the TGF-beta signaling and inhibition of matrix metalloproteinase in UVB-irradiated human fibroblast

artículo científico publicado en 2007

Increases in blood pressure and heart rate induced by caffeine are inhibited by (-)-epigallocatechin-3-O-gallate: involvement of catecholamines

artículo científico publicado en 2011

Inhibition of PDGF beta-receptor tyrosine phosphorylation and its downstream intracellular signal transduction in rat aortic vascular smooth muscle cells by kaempferol

scientific journal article

Inhibitory Effects of Docetaxel on Platelet-Derived Growth Factor (PDGF)-BB–Induced Proliferation of Vascular Smooth Muscle Cells Through Blocking PDGF-Receptor β Phosphorylation

artículo científico publicado el 1 de enero de 2011

Inhibitory effect of fenofibrate on neointima hyperplasia via G(0)/G(1) arrest of cell proliferation.

artículo científico publicado en 2010

Inhibitory effect of glycolic acid on ultraviolet B-induced c-fos expression, AP-1 activation and p53-p21 response in a human keratinocyte cell line

artículo científico publicado en 2002

Inhibitory effect of green tea extract on beta-amyloid-induced PC12 cell death by inhibition of the activation of NF-kappaB and ERK/p38 MAP kinase pathway through antioxidant mechanisms

artículo científico publicado en 2005

Inhibitory effect of obovatol on nitric oxide production and activation of NF-kappaB/MAP kinases in lipopolysaccharide-treated RAW 264.7cells

artículo científico publicado en 2006

Inhibitory effects of BST406, a newly synthesized benzylideneacetophenone derivative, on abnormal vascular smooth muscle cell proliferation

artículo científico publicado en 2010

Inhibitory effects of J78, a newly synthesized 1,4-naphthoquinone derivative, on experimental thrombosis and platelet aggregation

artículo científico

Inhibitory effects of OD 78 [3-(4-bromo-phenoxy)-4,5-dihydroxybenzoic acid-methyl ester] on the proliferation and migration of TNF-α-induced rat aortic smooth muscle cells

artículo científico publicado en 2011

Inhibitory effects of Tabebuia impetiginosa inner bark extract on platelet aggregation and vascular smooth muscle cell proliferation through suppressions of arachidonic acid liberation and ERK1/2 MAPK activation

artículo científico publicado en 2006

Inhibitory effects of paeonol on morphine-induced locomotor sensitization and conditioned place preference in mice

artículo científico publicado en 2006

Inhibitory effects of tetrandrine on the serum- and platelet-derived growth factor-BB-induced proliferation of rat aortic smooth muscle cells through inhibition of cell cycle progression, DNA synthesis, ERK1/2 activation and c-fos expression

artículo científico publicado en 2004

Inverse Relationship between Adipocyte Differentiation and Ceramide Level in 3T3-L1 Cells

artículo científico publicado el 1 de enero de 2011

JJK694, a synthesized obovatol derivative, inhibits platelet activation by suppressing cyclooxygenase and lipoxygenase activities

artículo científico publicado en 2012

JM91, a newly synthesized indoledione derivative, inhibits rat aortic vascular smooth muscle cells proliferation and cell cycle progression through inhibition of ERK1/2 and Akt activations

artículo científico publicado en 2007

JY0691, a newly synthesized obovatol derivative, inhibits cell cycle progression of rat aortic smooth muscle cells through up-regulation of p21(cip1).

artículo científico publicado en 2009

Korea red ginseng water extract increases nitric oxide concentrations in exhaled breath

artículo científico publicado en 2005

Local delivery of green tea catechins inhibits neointimal formation in the rat carotid artery injury model

artículo científico publicado en 2004

Luteolin prevents PDGF-BB-induced proliferation of vascular smooth muscle cells by inhibition of PDGF beta-receptor phosphorylation

artículo científico publicado en 2005

Melittin inhibits vascular smooth muscle cell proliferation through induction of apoptosis via suppression of nuclear factor-kappaB and Akt activation and enhancement of apoptotic protein expression

artículo científico

Mutant presenilin 2 increased oxidative stress and p53 expression in neuronal cells

artículo científico publicado en 2007

Mutant presenilin 2 increases acetylcholinesterase activity in neuronal cells

artículo científico publicado en 2005

Myriocin, a serine palmitoyltransferase inhibitor, suppresses tumor growth in a murine melanoma model by inhibiting de novo sphingolipid synthesis

artículo científico publicado el 15 de enero de 2012

Neuronal differentiation of embryonic midbrain cells by upregulation of peroxisome proliferator-activated receptor-gamma via the JNK-dependent pathway

artículo científico publicado en 2004

Neurotrophic activity of obovatol on the cultured embryonic rat neuronal cells by increase of neurotrophin release through activation of ERK pathway

artículo científico publicado el 21 de septiembre de 2010

Obovatol from Magnolia obovata inhibits vascular smooth muscle cell proliferation and intimal hyperplasia by inducing p21Cip1.

artículo científico publicado en 2009

Oleanolic acid, a pentacyclic triterpenoid, induces rabbit platelet aggregation through a phospholipase C-calcium dependent signaling pathway

artículo científico publicado en 2007

Peroxisome proliferator-activated receptor-gamma activator 15-deoxy-Delta12,14-prostaglandin J2 inhibits neuroblastoma cell growth through induction of apoptosis: association with extracellular signal-regulated kinase signal pathway

artículo científico

Pharmacological characterization of vasorelaxant effects of BMS-180448, a novel cardioselective ATP-sensitive potassium channel opener, in rat aorta

artículo científico publicado en 2003

Piperine inhibits the activities of platelet cytosolic phospholipase A2 and thromboxane A2 synthase without affecting cyclooxygenase-1 activity: different mechanisms of action are involved in the inhibition of platelet aggregation and macrophage inf

artículo científico publicado en 2014

Piperlongumine inhibits atherosclerotic plaque formation and vascular smooth muscle cell proliferation by suppressing PDGF receptor signaling

artículo científico publicado en 2012

Potent inhibition of serum-stimulated responses in vascular smooth muscle cell proliferation by 2-chloro-3-(4-hexylphenyl)-amino-1,4-naphthoquinone, a newly synthesized 1,4-naphthoquinone derivative

artículo científico publicado en 2007

Potentiation of vasoconstriction and pressor response by low concentration of monomethylarsonous acid (MMA(III)).

artículo científico publicado en 2011

Prenylated xanthones from the root bark of Cudrania tricuspidata

artículo científico publicado en 2007

Protection of LLC-PK1 cells against hydrogen peroxide-induced cell death by modulation of ceramide level

artículo científico publicado en 2005

Pterostilbene, a natural dimethylated analog of resveratrol, inhibits rat aortic vascular smooth muscle cell proliferation by blocking Akt-dependent pathway

artículo científico publicado en 2010

Quantitative analysis of sphingomyelin by high-performance liquid chromatography after enzymatic hydrolysis

artículo científico publicado en 2012

Rhamnetin-induced suppression of clonal expansion during early stage of adipogenesis

artículo científico publicado el 30 de junio de 2012

Sauchinone Attenuates Oxidative Stress-Induced Skeletal Muscle Myoblast Damage through the Down-Regulation of Ceramide

artículo científico publicado el 1 de enero de 2011

Simultaneous HPLC analysis of ceramide and dihydroceramide in human hairs

artículo científico publicado en 2009

Simultaneous analysis of d-3-methoxy-17-methylmorphinan and l-3-methoxy-17-methylmorphinan by high pressure liquid chromatography equipped with PDA.

artículo científico publicado en 2006

Structure activity relationship of antioxidative property of flavonoids and inhibitory effect on matrix metalloproteinase activity in UVA-irradiated human dermal fibroblast

artículo científico

Sulforaphane Inhibits Mitotic Clonal Expansion During Adipogenesis Through Cell Cycle Arrest

artículo científico publicado el 26 de enero de 2012

Sulforaphane attenuates obesity by inhibiting adipogenesis and activating the AMPK pathway in obese mice

artículo científico publicado en 2013

Sulforaphane inhibits PDGF-induced proliferation of rat aortic vascular smooth muscle cell by up-regulation of p53 leading to G1/S cell cycle arrest

artículo científico publicado el 26 de junio de 2013

Synergistic activation of monocytes by polysaccharides isolated from Salicornia herbacea and interferon-gamma

artículo científico publicado en 2006

Synthesis and anti-platelet activity of obovatol derivatives

artículo científico publicado en 2011

The inhibitory effect and mechanism of luteolin 7-glucoside on rat aortic vascular smooth muscle cell proliferation

artículo científico publicado en 2006

The isolation and antioxidative effects of vitexin from Acer palmatum

artículo científico publicado en 2005

The protective effects of paclitaxel on platelet aggregation through the inhibition of thromboxane A2 synthase.

artículo científico publicado en 2010

Truncation of NH2-terminal amino acid residues increases agonistic potency of leukotactin-1 on CC chemokine receptors 1 and 3.

artículo científico publicado en 2002

Vascular smooth muscle dysfunction induced by monomethylarsonous acid (MMA III): a contributing factor to arsenic-associated cardiovascular diseases

artículo científico publicado en 2008

YSK2821, a newly synthesized indoledione derivative, inhibits cell proliferation and cell cycle progression via the cell cycle-related proteins by regulating phosphatidylinositol-3 kinase cascade in vascular smooth muscle cells

artículo científico publicado en 2008