Lista de obras -

A hypomorphic PIGA gene mutation causes severe defects in neuron development and susceptibility to complement-mediated toxicity in a human iPSC model

artículo científico publicado en 2017

A long noncoding RNA contributes to neuropathic pain by silencing Kcna2 in primary afferent neurons

artículo científico publicado en 2013

A subpopulation of nociceptors specifically linked to itch

artículo científico publicado en 2012

Activation of MrgC receptor inhibits N-type calcium channels in small-diameter primary sensory neurons in mice

artículo científico publicado en 2014

Activation of Peripheral μ-opioid Receptors by Dermorphin [D-Arg2, Lys4] (1-4) Amide Leads to Modality-preferred Inhibition of Neuropathic Pain

artículo científico publicado en 2016

Activation of cannabinoid CB1 receptor contributes to suppression of spinal nociceptive transmission and inhibition of mechanical hypersensitivity by Aβ-fiber stimulation

artículo científico publicado en 2016

Agonists of the MAS-related gene (Mrgs) orphan receptors as novel mediators of mast cell-sensory nerve interactions

artículo científico publicado en 2008

An Itch To Be Scratched ⬇️

artículo científico publicado el 4 de noviembre de 2010

Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family

artículo científico publicado en 2003

BAM8-22 peptide produces itch and nociceptive sensations in humans independent of histamine release

artículo científico publicado en 2011

Central terminal sensitization of TRPV1 by descending serotonergic facilitation modulates chronic pain

artículo científico publicado en 2014

Conventional and kilohertz-frequency spinal cord stimulation produces intensity- and frequency-dependent inhibition of mechanical hypersensitivity in a rat model of neuropathic pain

scientific article published on August 2013

Development and evaluation of small peptidomimetic ligands to protease-activated receptor-2 (PAR2) through the use of lipid tethering

artículo científico publicado en 2014

Different activation signals induce distinct mast cell degranulation strategies

artículo científico publicado en 2016

Discovery and characterization of 2-(cyclopropanesulfonamido)-N-(2-ethoxyphenyl)benzamide, ML382: a potent and selective positive allosteric modulator of MrgX1.

artículo científico publicado en 2014

Distinct and common expression of receptors for inflammatory mediators in vagal nodose versus jugular capsaicin-sensitive/TRPV1-positive neurons detected by low input RNA sequencing

artículo científico publicado en 2017

Electrical stimulation of dorsal root entry zone attenuates wide-dynamic-range neuronal activity in rats

artículo científico publicado en 2014

Electrical stimulation of low-threshold afferent fibers induces a prolonged synaptic depression in lamina II dorsal horn neurons to high-threshold afferent inputs in mice

artículo científico publicado en 2015

Enhanced excitability of MRGPRA3- and MRGPRD-positive nociceptors in a model of inflammatory itch and pain

artículo científico publicado en 2014

Functional Coupling with Cardiac Muscle Promotes Maturation of hPSC-Derived Sympathetic Neurons

artículo científico publicado en 2016

Identification of a mast-cell-specific receptor crucial for pseudo-allergic drug reactions

artículo científico publicado en 2015

Investigating the role of MRGPRC11 and capsaicin-sensitive afferent nerves in the anti-influenza effects exerted by SLIGRL-amide in murine airways

artículo científico publicado en 2016

Investigation of Pain Mechanisms by Calcium Imaging Approaches

artículo científico publicado en 2017

Itch mechanisms and circuits

artículo científico publicado en 2014

Itch: Cells, Molecules, and Circuits

scientific article published on January 2011

Mas-Related G Protein-Coupled Receptors Offer Potential New Targets for Pain Therapy

artículo científico publicado en 2016

Mas-Related G Protein-Coupled Receptors and the Biology of Itch Sensation

artículo científico publicado en 2017

Mas-related G-protein–coupled receptors inhibit pathological pain in mice ⬇️

artículo científico publicado el 19 de agosto de 2010

Mechanisms of itch evoked by β-alanine

artículo científico publicado en 2012

MrgC agonism at central terminals of primary sensory neurons inhibits neuropathic pain

scientific article published on 11 December 2013

Orphan G protein-coupled receptors MrgA1 and MrgC11 are distinctively activated by RF-amide-related peptides through the Galpha q/11 pathway

artículo científico publicado en 2002

Peripheral mechanisms of itch

artículo científico publicado en 2012

Pirt contributes to uterine contraction-induced pain in mice

artículo científico publicado en 2015

Pirt functions as an endogenous regulator of TRPM8.

artículo científico publicado en 2013

Pirt, a TRPV1 modulator, is required for histamine-dependent and -independent itch

artículo científico publicado en 2011

Pirt, a phosphoinositide-binding protein, functions as a regulatory subunit of TRPV1

scientific journal article

Preso1 dynamically regulates group I metabotropic glutamate receptors

artículo científico publicado en 2012

Redefining the concept of protease-activated receptors: cathepsin S evokes itch via activation of Mrgprs

artículo científico publicado en 2015

Saikosaponin A inhibits compound 48/80-induced pseudo-allergy via the Mrgprx2 pathway in vitro and in vivo

artículo científico publicado en 2017

Selective keratinocyte stimulation is sufficient to evoke nociception in mice

artículo científico publicado en 2015

Sensory neuron-specific GPCR Mrgprs are itch receptors mediating chloroquine-induced pruritus

artículo científico publicado en 2009

Sensory neurons and circuits mediating itch

artículo científico

TLR3 deficiency impairs spinal cord synaptic transmission, central sensitization, and pruritus in mice

artículo científico publicado en 2012

TRPA1 is required for histamine-independent, Mas-related G protein-coupled receptor-mediated itch

artículo científico

Targeting human Mas-related G protein-coupled receptor X1 to inhibit persistent pain

artículo científico publicado en 2017

The cell biology of acute itch

artículo científico publicado en 2016

The distinct roles of two GPCRs, MrgprC11 and PAR2, in itch and hyperalgesia

artículo científico publicado en 2011

The role of the Mrgpr receptor family in itch

artículo científico

Three functionally distinct classes of C-fibre nociceptors in primates

artículo científico publicado en 2014

Tmem100 Is a Regulator of TRPA1-TRPV1 Complex and Contributes to Persistent Pain

scientific journal article

Tolerance develops to the antiallodynic effects of the peripherally acting opioid loperamide hydrochloride in nerve-injured rats

scientific article published on 20 July 2013

Trp channels and itch

artículo científico publicado en 2015

Use of the relative release index for histamine in LAD2 cells to evaluate the potential anaphylactoid effects of drugs

artículo científico publicado en 2017

Voltage-gated potassium channels involved in regulation of physiological function in MrgprA3-specific itch neurons

artículo científico publicado en 2016

miR-365 targets β-arrestin 2 to reverse morphine tolerance in rats

artículo científico publicado en 2016

Lista de obras de

A hypomorphic PIGA gene mutation causes severe defects in neuron development and susceptibility to complement-mediated toxicity in a human iPSC model

A long noncoding RNA contributes to neuropathic pain by silencing Kcna2 in primary afferent neurons

A subpopulation of nociceptors specifically linked to itch

Activation of MrgC receptor inhibits N-type calcium channels in small-diameter primary sensory neurons in mice

Activation of Peripheral μ-opioid Receptors by Dermorphin [D-Arg2, Lys4] (1-4) Amide Leads to Modality-preferred Inhibition of Neuropathic Pain

Activation of cannabinoid CB1 receptor contributes to suppression of spinal nociceptive transmission and inhibition of mechanical hypersensitivity by Aβ-fiber stimulation

Agonists of the MAS-related gene (Mrgs) orphan receptors as novel mediators of mast cell-sensory nerve interactions

An Itch To Be Scratched ⬇️

Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family

BAM8-22 peptide produces itch and nociceptive sensations in humans independent of histamine release

Central terminal sensitization of TRPV1 by descending serotonergic facilitation modulates chronic pain

Conventional and kilohertz-frequency spinal cord stimulation produces intensity- and frequency-dependent inhibition of mechanical hypersensitivity in a rat model of neuropathic pain

Development and evaluation of small peptidomimetic ligands to protease-activated receptor-2 (PAR2) through the use of lipid tethering

Different activation signals induce distinct mast cell degranulation strategies

Discovery and characterization of 2-(cyclopropanesulfonamido)-N-(2-ethoxyphenyl)benzamide, ML382: a potent and selective positive allosteric modulator of MrgX1.

Distinct and common expression of receptors for inflammatory mediators in vagal nodose versus jugular capsaicin-sensitive/TRPV1-positive neurons detected by low input RNA sequencing

Electrical stimulation of dorsal root entry zone attenuates wide-dynamic-range neuronal activity in rats

Electrical stimulation of low-threshold afferent fibers induces a prolonged synaptic depression in lamina II dorsal horn neurons to high-threshold afferent inputs in mice

Enhanced excitability of MRGPRA3- and MRGPRD-positive nociceptors in a model of inflammatory itch and pain

Functional Coupling with Cardiac Muscle Promotes Maturation of hPSC-Derived Sympathetic Neurons

Identification of a mast-cell-specific receptor crucial for pseudo-allergic drug reactions

Investigating the role of MRGPRC11 and capsaicin-sensitive afferent nerves in the anti-influenza effects exerted by SLIGRL-amide in murine airways

Investigation of Pain Mechanisms by Calcium Imaging Approaches

Itch mechanisms and circuits

Itch: Cells, Molecules, and Circuits

Mas-Related G Protein-Coupled Receptors Offer Potential New Targets for Pain Therapy

Mas-Related G Protein-Coupled Receptors and the Biology of Itch Sensation

Mas-related G-protein–coupled receptors inhibit pathological pain in mice ⬇️

Mechanisms of itch evoked by β-alanine

MrgC agonism at central terminals of primary sensory neurons inhibits neuropathic pain

Orphan G protein-coupled receptors MrgA1 and MrgC11 are distinctively activated by RF-amide-related peptides through the Galpha q/11 pathway

Peripheral mechanisms of itch

Pirt contributes to uterine contraction-induced pain in mice

Pirt functions as an endogenous regulator of TRPM8.

Pirt, a TRPV1 modulator, is required for histamine-dependent and -independent itch

Pirt, a phosphoinositide-binding protein, functions as a regulatory subunit of TRPV1

Preso1 dynamically regulates group I metabotropic glutamate receptors

Redefining the concept of protease-activated receptors: cathepsin S evokes itch via activation of Mrgprs

Saikosaponin A inhibits compound 48/80-induced pseudo-allergy via the Mrgprx2 pathway in vitro and in vivo

Selective keratinocyte stimulation is sufficient to evoke nociception in mice

Sensory neuron-specific GPCR Mrgprs are itch receptors mediating chloroquine-induced pruritus

Sensory neurons and circuits mediating itch

TLR3 deficiency impairs spinal cord synaptic transmission, central sensitization, and pruritus in mice

TRPA1 is required for histamine-independent, Mas-related G protein-coupled receptor-mediated itch

Targeting human Mas-related G protein-coupled receptor X1 to inhibit persistent pain

The cell biology of acute itch

The distinct roles of two GPCRs, MrgprC11 and PAR2, in itch and hyperalgesia

The role of the Mrgpr receptor family in itch

Three functionally distinct classes of C-fibre nociceptors in primates

Tmem100 Is a Regulator of TRPA1-TRPV1 Complex and Contributes to Persistent Pain

Tolerance develops to the antiallodynic effects of the peripherally acting opioid loperamide hydrochloride in nerve-injured rats

Trp channels and itch

Use of the relative release index for histamine in LAD2 cells to evaluate the potential anaphylactoid effects of drugs

Voltage-gated potassium channels involved in regulation of physiological function in MrgprA3-specific itch neurons

miR-365 targets β-arrestin 2 to reverse morphine tolerance in rats