Filtros de búsqueda

Lista de obras de Stefan Endres

5'-Triphosphate RNA is the ligand for RIG-I

artículo científico publicado en 2006

5'-Triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma

artículo científico publicado en 2008

5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I

artículo científico publicado en 2009

50 Jahre Fortschritte in der Arzneimitteltherapie – Rückblick und Ausblick

artículo científico publicado en 2016

A modular and controllable T cell therapy platform for acute myeloid leukemia

scientific article published on 07 January 2021

A novel TLR7 agonist reverses NK cell anergy and cures RMA-S lymphoma-bearing mice

artículo científico publicado en 2016

A novel complete autosomal recessive STAT1 LOF variant causes immunodeficiency with hemophagocytic lymphohistiocytosis-like hyperinflammation

artículo científico publicado en 2020

Activation of melanoma differentiation-associated gene 5 causes rapid involution of the thymus.

artículo científico publicado en 2009

Activation with CpG-A and CpG-B oligonucleotides reveals two distinct regulatory pathways of type I IFN synthesis in human plasmacytoid dendritic cells.

artículo científico publicado en 2003

Adrenaline enhances LPS-induced IL-10 synthesis: evidence for protein kinase A-mediated pathway

article

Advances in cancer immunotherapy 2019 - latest trends

scientific article published on 19 June 2019

An ISCOM vaccine combined with a TLR9 agonist breaks immune evasion mediated by regulatory T cells in an orthotopic model of pancreatic carcinoma.

artículo científico publicado en 2011

Analysis of FoxP3+ T-regulatory cells and CD8+ T-cells in ovarian carcinoma: location and tumor infiltration patterns are key prognostic markers

artículo científico publicado en 2014

Analysis of plasmacytoid and myeloid dendritic cells in nasal epithelium

artículo científico publicado en 2006

Apoptotic pancreatic tumor cells are superior to cell lysates in promoting cross-priming of cytotoxic T cells and activate NK and gammadelta T cells.

artículo científico publicado en 2002

B-cell lymphomas differ in their responsiveness to CpG oligodeoxynucleotides

artículo científico publicado en 2005

Biocompatibility testing of different sterilised or disinfected allogenous bone grafts in comparison to the gold standard of autologous bone grafts--an "in vitro" analysis of immunomodulation

artículo científico publicado en 2005

Bispecific Antibodies Enable Synthetic Agonistic Receptor-Transduced T Cells for Tumor Immunotherapy

scientific article published on 08 July 2019

Blocking inflammation on the way: Rationale for CXCR2 antagonists for the treatment of COVID-19

artículo científico publicado en 2020

C-C chemokine receptor type-4 transduction of T cells enhances interaction with dendritic cells, tumor infiltration and therapeutic efficacy of adoptive T cell transfer

artículo científico publicado en 2015

CCL1 is a major regulatory T cell attracting factor in human breast cancer

artículo científico publicado en 2018

CCL22 controls immunity by promoting regulatory T cell communication with dendritic cells in lymph nodes

artículo científico publicado en 2019

CD103 is a hallmark of tumor-infiltrating regulatory T cells

artículo científico publicado en 2011

Can we use interleukin-1β blockade for lung cancer treatment?

artículo científico publicado en 2018

Cancer cell-derived IL-1α induces CCL22 and the recruitment of regulatory T cells

artículo científico publicado en 2016

Cancer cells induce interleukin-22 production from memory CD4+ T cells via interleukin-1 to promote tumor growth

artículo científico publicado en 2017

Cellular Immunostimulation by CpG-Sequence-Coated DNA Origami Structures

artículo científico publicado en 2011

Challenges in Clinical Trial Design for T Cell-Based Cancer Immunotherapy

artículo científico publicado en 2019

Chemosensitization of pancreatic carcinoma cells to enhance T cell-mediated cytotoxicity induced by tumor lysate-pulsed dendritic cells

artículo científico publicado en 2005

Cicaprost and the type IV phosphodiesterase inhibitor, rolipram, synergize in suppression of tumor necrosis factor-alpha synthesis

scientific article published on 01 March 1996

Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome

artículo científico publicado en 2010

Combined dendritic cell- and CpG oligonucleotide-based immune therapy cures large murine tumors that resist chemotherapy

artículo científico publicado en 2002

Combined use of toll-like receptor agonists and prostaglandin E(2) in the FastDC model: rapid generation of human monocyte-derived dendritic cells capable of migration and IL-12p70 production

artículo científico publicado en 2008

Concomitant gemcitabine therapy negatively affects DC vaccine-induced CD8(+) T-cell and B-cell responses but improves clinical efficacy in a murine pancreatic carcinoma model.

artículo científico publicado en 2014

Constitutive Expression of CCL22 Is Mediated by T Cell-Derived GM-CSF

scientific article published on 09 September 2020

Correction to: Immunostimulatory RNA leads to functional reprogramming of myeloid-derived suppressor cells in pancreatic cancer

scientific article published on 16 December 2019

CpG ODN enhance antigen-specific NKT cell activation via plasmacytoid dendritic cells

artículo científico publicado en 2005

CpG blocks immunosuppression by myeloid-derived suppressor cells in tumor-bearing mice

artículo científico publicado en 2011

CpG oligonucleotides induce strong humoral but only weak CD4+ T cell responses to protein antigens in rhesus macaques in vivo

article

CpG-A Oligonucleotides Induce a Monocyte-Derived Dendritic Cell-Like Phenotype That Preferentially Activates CD8 T Cells

artículo científico publicado en 2003

CpG-A and CpG-B oligonucleotides differentially enhance human peptide-specific primary and memory CD8+ T-cell responses in vitro

article

Cytokine profile of a human bone marrow cell culture on exposure to titanium-aluminium-vanadium particles

artículo científico publicado en 2002

Cytosolic DNA triggers mitochondrial apoptosis via DNA damage signaling proteins independently of AIM2 and RNA polymerase III.

artículo científico publicado en 2011

Cytosolic RIG-I-like helicases act as negative regulators of sterile inflammation in the CNS.

artículo científico publicado en 2011

D-dopachrome tautomerase (D-DT or MIF-2): Doubling the MIF cytokine family ⬇️

artículo científico publicado el 14 de abril de 2012

DNA vaccination efficiently induces antibodies to Nogo-A and does not exacerbate experimental autoimmune encephalomyelitis

artículo científico publicado en 2008

Delivery by Cationic Gelatin Nanoparticles Strongly Increases the Immunostimulatory Effects of CpG Oligonucleotides

article

Delivery of immunostimulatory RNA oligonucleotides by gelatin nanoparticles triggers an efficient antitumoral response.

artículo científico publicado en 2010

Dendritic cell-based vaccination combined with gemcitabine increases survival in a murine pancreatic carcinoma model

artículo científico publicado en 2007

Dendritic cell-based vaccination of patients with advanced pancreatic carcinoma: results of a pilot study

artículo científico publicado en 2011

Determinants of response and resistance to CAR T cell therapy

artículo científico publicado en 2019

Determination of thiopurine S-methyltransferase phenotype using thin-layer chromatography and quantitative scanning

artículo científico publicado en 2002

Development of a new protocol for 2-day generation of mature dendritic cells from human monocytes ⬇️

artículo científico publicado el 24 de octubre de 2003

Dying cells expose a nuclear antigen cross-reacting with anti-PD-1 monoclonal antibodies.

artículo científico publicado en 2018

Editorial

artículo científico publicado en 2017

Editorial

scientific article published on 15 November 2019

Editorial

scientific article published on 19 November 2018

Efficient eradication of subcutaneous but not of autochthonous gastric tumors by adoptive T cell transfer in an SV40 T antigen mouse model

artículo científico publicado en 2010

Endogenous adenosine curtails lipopolysaccharide-stimulated tumour necrosis factor synthesis

scientific article published on 01 February 1997

Enhanced Dendritic Cell Maturation by TNF- or Cytidine-Phosphate-Guanosine DNA Drives T Cell Activation In Vitro and Therapeutic Anti-Tumor Immune Responses In Vivo

article

Enhancing tumor T cell infiltration to enable cancer immunotherapy

scientific article published on 01 February 2019

Expression of CCL22 and Infiltration by Regulatory T Cells are Increased in the Decidua of Human Miscarriage Placentas

artículo científico publicado en 2015

Extracellular ATP and TNF-alpha synergize in the activation and maturation of human dendritic cells

scientific article published on 01 October 2000

FOXP3+ Cells Recruited by CCL22 into Breast Cancer Correlates with Less Tumor Nodal Infiltration

artículo científico publicado en 2016

FastDC derived from human monocytes within 48 h effectively prime tumor antigen-specific cytotoxic T cells

artículo científico publicado en 2005

High-affinity CD16-polymorphism and Fc-engineered antibodies enable activity of CD16-chimeric antigen receptor-modified T cells for cancer therapy

scientific article published on 15 November 2018

IFN-alpha promotes definitive maturation of dendritic cells generated by short-term culture of monocytes with GM-CSF and IL-4

artículo científico publicado en 2006

IL-12p70-dependent Th1 induction by human B cells requires combined activation with CD40 ligand and CpG DNA.

artículo científico

ISCOMATRIX adjuvant combines immune activation with antigen delivery to dendritic cells in vivo leading to effective cross-priming of CD8+ T cells.

artículo científico publicado en 2011

ISCOMATRIX adjuvant induces efficient cross-presentation of tumor antigen by dendritic cells via rapid cytosolic antigen delivery and processing via tripeptidyl peptidase II.

artículo científico publicado en 2009

Identification and functional analysis of tumor-infiltrating plasmacytoid dendritic cells in head and neck cancer ⬇️

artículo científico publicado el 1 de octubre de 2003

Immune response to functionalized mesoporous silica nanoparticles for targeted drug delivery.

artículo científico publicado en 2015

Immunostimulatory RNA Blocks Suppression by Regulatory T Cells

artículo científico publicado en 2009

Immunostimulatory RNA leads to functional reprogramming of myeloid-derived suppressor cells in pancreatic cancer

scientific article published on 06 November 2019

Immunostimulatory RNA oligonucleotides induce an effective antitumoral NK cell response through the TLR7.

artículo científico publicado en 2009

Immunostimulatory RNA oligonucleotides trigger an antigen-specific cytotoxic T-cell and IgG2a response

artículo científico publicado en 2007

Immunostimulatory properties of CpG-oligonucleotides are enhanced by the use of protamine nanoparticles.

artículo científico publicado en 2006

Immunotherapy in Tumors.

artículo científico publicado en 2015

Immunotherapy with dendritic cells and CpG oligonucleotides can be combined with chemotherapy without loss of efficacy in a mouse model of colon cancer

artículo científico publicado en 2006

Impact of a New Fusion Receptor on PD-1-Mediated Immunosuppression in Adoptive T Cell Therapy

artículo científico publicado en 2015

In breast cancer, a high ratio of tumour‐infiltrating intraepithelial CD8+ to FoxP3+ cells is characteristic for the medullary subtype ⬇️

artículo científico publicado el 1 de noviembre de 2011

In vivo synthesis of tumor necrosis factor-alpha in healthy humans after live yellow fever vaccination.

artículo científico publicado en 1998

Inflammatory bowel disease: no association between allele combinations of the interleukin (IL) I beta and IL-I receptor antagonist gene polymorphisms

artículo científico publicado en 1998

Inhibition of toll-like receptor 7- and 9-mediated alpha/beta interferon production in human plasmacytoid dendritic cells by respiratory syncytial virus and measles virus

artículo científico publicado en 2005

Interferon-alpha disables dendritic cell precursors: dendritic cells derived from interferon-alpha-treated monocytes are defective in maturation and T-cell stimulation

artículo científico publicado en 2003

Interleukin-1 receptor-associated kinase-M suppresses systemic lupus erythematosus.

artículo científico publicado en 2011

Interleukin-22 Is Frequently Expressed in Small- and Large-Cell Lung Cancer and Promotes Growth in Chemotherapy-Resistant Cancer Cells ⬇️

artículo científico publicado el 1 de agosto de 2013

Interleukin-22 is elevated in lavage from patients with lung cancer and other pulmonary diseases

artículo científico publicado en 2016

Killing Mechanisms of Chimeric Antigen Receptor (CAR) T Cells ⬇️

artículo científico publicado en 2019

Limitations in the Design of Chimeric Antigen Receptors for Cancer Therapy.

artículo científico publicado en 2019

Mature dendritic cells derived from human monocytes within 48 hours: a novel strategy for dendritic cell differentiation from blood precursors

artículo científico publicado en 2003

Microphthalmia-Associated Transcription Factor (MITF) Regulates Immune Cell Migration into Melanoma

artículo científico publicado en 2018

Modes of action of TLR7 agonists in cancer therapy

artículo científico publicado en 2014

Morphological and immunocytochemical characteristics indicate the yield of early progenitors and represent a quality control for human mesenchymal stem cell culturing.

artículo científico publicado en 2009

Mycoplasma hyorhinis-Contaminated Cell Lines Activate Primary Innate Immune Cells via a Protease-Sensitive Factor

artículo científico publicado en 2015

New approaches for the treatment of neurological diseases

artículo científico publicado en 2013

Nitric oxide downregulates tumour necrosis factor mRNA in RAW 264.7 cells ⬇️

artículo científico publicado el 1 de febrero de 1998

Nlrp3-dependent IL-1β inhibits CD103+ dendritic cell differentiation in the gut.

artículo científico publicado en 2018

No indication for a defect in toll-like receptor signaling in patients with hyper-IgE syndrome

artículo científico publicado en 2005

Oligodeoxynucleotides enhance lipopolysaccharide-stimulated synthesis of tumor necrosis factor: dependence on phosphorothioate modification and reversal by heparin.

artículo científico publicado en 1996

Oligonucleotides: Extrapolating from in vitro to in vivo ⬇️

artículo científico publicado el 1 de julio de 1997

P10. Concomitant gemcitabine therapy negatively affects DC vaccine-induced CD8+ T cell and B cell responses but improves clinical efficacy in a murine pancreatic carcinoma model.

artículo científico publicado en 2014

P17. RIG-I-like helicases induce immunogenic cell death of pancreatic cancer cells

artículo científico publicado en 2014

P2Y receptor signaling regulates phenotype and IFN-alpha secretion of human plasmacytoid dendritic cells

artículo científico publicado en 2007

P68. A new EGFR - EpCAM bispecific antibody enhances the efficacy of adoptive T-cell therapy in a murine gastric tumour model

artículo científico publicado en 2014

PD1-CD28 Fusion Protein Enables CD4+ T Cell Help for Adoptive T Cell Therapy in Models of Pancreatic Cancer and Non-hodgkin Lymphoma

scientific article published on 30 August 2018

Pattern recognition of viral nucleic acids by RIG-I-like helicases ⬇️

artículo científico publicado el 4 de septiembre de 2010

Peritumoral CpG DNA elicits a coordinated response of CD8 T cells and innate effectors to cure established tumors in a murine colon carcinoma model

artículo científico publicado en 2002

Peritumoural CCL1 and CCL22 expressing cells in hepatocellular carcinomas shape the tumour immune infiltrate

artículo científico publicado en 2019

Phosphodiesterase type 4 inhibitor suppresses expression of anti-apoptotic members of the Bcl-2 family in B-CLL cells and induces caspase-dependent apoptosis.

artículo científico publicado en 2001

Plasmacytoid dendritic cells control TLR7 sensitivity of naive B cells via type I IFN.

artículo científico publicado en 2005

Plasmacytoid dendritic cells, antigen, and CpG-C license human B cells for plasma cell differentiation and immunoglobulin production in the absence of T-cell help

artículo científico publicado en 2003

Plasmacytoid dendritic cells: a new cutaneous dendritic cell subset with distinct role in inflammatory skin diseases

artículo científico publicado en 2002

Plasmacytoid dendritic cells: the key to CpG.

artículo científico publicado en 2002

Polymorphisms in melanoma differentiation-associated gene 5 link protein function to clearance of hepatitis C virus

artículo científico publicado en 2015

Proapoptotic and antiapoptotic proteins of the Bcl-2 family regulate sensitivity of pancreatic cancer cells toward gemcitabine and T-cell-mediated cytotoxicity

artículo científico publicado en 2015

Proapoptotic signaling induced by RIG-I and MDA-5 results in type I interferon-independent apoptosis in human melanoma cells.

artículo científico publicado en 2009

Protease-activation using anti-idiotypic masks enables tumor specificity of a folate receptor 1-T cell bispecific antibody

artículo científico publicado en 2020

Protective and aggravating effects of Nlrp3 inflammasome activation in IBD models: influence of genetic and environmental factors

artículo científico publicado en 2012

Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides

artículo científico publicado en 2002

RIG-I-based immunotherapy enhances survival in preclinical AML models and sensitizes AML cells to checkpoint blockade

scientific article published on 18 November 2019

RIG-I-like helicases induce immunogenic cell death of pancreatic cancer cells and sensitize tumors toward killing by CD8(+) T cells

artículo científico publicado en 2014

RIG-I-like helicases induce immunogenic cell death of pancreatic cancer cells and sensitize tumors toward killing by CD8+ T cells.

artículo científico publicado en 2014

Rational design of new CpG oligonucleotides that combine B cell activation with high IFN-alpha induction in plasmacytoid dendritic cells

artículo científico publicado en 2003

Recent advances in immunostimulatory CpG oligonucleotides.

artículo científico publicado en 2003

Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production

artículo científico publicado en 2009

Replication-dependent potent IFN-alpha induction in human plasmacytoid dendritic cells by a single-stranded RNA virus

artículo científico publicado en 2004

Reply

S81. Proffered paper: A new PD1-CD28 chimeric receptor overcomes PD-1-mediated immunosuppression in adoptive T cell therapy

article

Selection of molecular structure and delivery of RNA oligonucleotides to activate TLR7 versus TLR8 and to induce high amounts of IL-12p70 in primary human monocytes.

artículo científico publicado en 2009

Selective bispecific T cell recruiting antibody and antitumor activity of adoptive T cell transfer.

artículo científico publicado en 2014

Self-priming determines high type I IFN production by plasmacytoid dendritic cells

artículo científico publicado en 2014

Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7

artículo científico publicado en 2005

Shock waves: a novel method for cytoplasmic delivery of antisense oligonucleotides.

artículo científico publicado en 2001

Short-term activation induces multifunctional dendritic cells that generate potent antitumor T-cell responses in vivo

artículo científico publicado en 2008

Spontaneous Formation of Nucleic Acid-based Nanoparticles Is Responsible for High Interferon-α Induction by CpG-A in Plasmacytoid Dendritic Cells

artículo científico publicado en 2004

Staphylococcus aureus Protein A Triggers T Cell-Independent B Cell Proliferation by Sensitizing B Cells for TLR2 Ligands

artículo científico publicado en 2007

Strategies to relieve immunosuppression in pancreatic cancer.

artículo científico

Structural studies of oligonucleotides containing G-quadruplex motifs using AFM.

artículo científico

Superior protective immunity against murine listeriosis by combined vaccination with CpG DNA and recombinant Salmonella enterica serovar typhimurium.

artículo científico publicado en 2009

Suppression of intratumoral CCL22 by type i interferon inhibits migration of regulatory T cells and blocks cancer progression.

artículo científico publicado en 2015

Suppression of tumor necrosis factor-α production by interleukin-10 is enhanced by cAMP-elevating agents

scientific article published on 01 February 1997

Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence

artículo científico publicado en 2009

Systemic but not MDSC-specific IRF4 deficiency promotes an immunosuppressed tumor microenvironment in a murine pancreatic cancer model

scientific article published on 24 May 2020

Systemic cancer therapy with a small molecule agonist of toll-like receptor 7 can be improved by circumventing TLR tolerance

artículo científico publicado en 2011

T cell-independent, TLR-induced IL-12p70 production in primary human monocytes

artículo científico publicado en 2006

TLR Activation Excludes Circulating Naive CD8+ T Cells from Gut-Associated Lymphoid Organs in Mice ⬇️

artículo científico publicado el 15 de abril de 2013

TLR and RLR Signaling Are Reprogrammed in Opposite Directions after Detection of Viral Infection

artículo científico publicado en 2015

TLR8-driven IL-12-dependent reciprocal and synergistic activation of NK cells and monocytes by immunostimulatory RNA.

artículo científico publicado en 2009

Targeted activation of melanoma differentiation-associated protein 5 (MDA5) for immunotherapy of pancreatic carcinoma.

artículo científico publicado en 2015

Targeting CpG oligonucleotides to the lymph node by nanoparticles elicits efficient antitumoral immunity

artículo científico publicado en 2008

Targeting interleukin-22 for cancer therapy

artículo científico publicado en 2018

Teaching an old dog new tricks: next-generation CAR T cells

artículo científico publicado en 2019

The ICE inhibitor pralnacasan prevents DSS-induced colitis in C57BL/6 mice and suppresses IP-10 mRNA but not TNF-alpha mRNA expression

scientific article published on 28 March 2007

The interleukin-1 beta-converting enzyme inhibitor pralnacasan reduces dextran sulfate sodium-induced murine colitis and T helper 1 T-cell activation

artículo científico publicado en 2003

The macrophage migration inhibitory factor (MIF)-homologue D-dopachrome tautomerase is a therapeutic target in a murine melanoma model

artículo científico publicado en 2014

The neural crest transcription factor Brn3a is expressed in melanoma and required for cell cycle progression and survival

artículo científico publicado en 2013

The selective phosphodiesterase 4 inhibitor roflumilast and phosphodiesterase 3/4 inhibitor pumafentrine reduce clinical score and TNF expression in experimental colitis in mice

artículo científico publicado en 2013

The specific type-4 phosphodiesterase inhibitor mesopram alleviates experimental colitis in mice

artículo científico publicado en 2003

Therapeutic efficacy of bifunctional siRNA combining TGF-β1 silencing with RIG-I activation in pancreatic cancer

artículo científico publicado en 2013

Therapie allergischer Erkrankungen – Stand und Ausblick

artículo científico publicado en 2020

Toll-like receptor expression reveals CpG DNA as a unique microbial stimulus for plasmacytoid dendritic cells which synergizes with CD40 ligand to induce high amounts of IL-12

artículo científico publicado en 2001

Total hip replacement in childhood, adolescence and young patients: a review of the literature

artículo científico publicado en 2004

Tumor cell lysate-pulsed human dendritic cells induce a T-cell response against pancreatic carcinoma cells: an in vitro model for the assessment of tumor vaccines

artículo científico publicado en 2001

Tumour-derived prostaglandin E and transforming growth factor-beta synergize to inhibit plasmacytoid dendritic cell-derived interferon-alpha

artículo científico publicado en 2009

Utility of the RIG-I Agonist Triphosphate RNA for Melanoma Therapy

artículo científico publicado en 2019

Viral 5'-triphosphate RNA and non-CpG DNA aggravate autoimmunity and lupus nephritis via distinct TLR-independent immune responses

scientific article published on 01 December 2008

Virus-associated activation of innate immunity induces rapid disruption of Peyer's patches in mice

artículo científico publicado en 2013

[Biocompatibility testing of various biomaterials as dependent on immune status]

artículo científico publicado en 2004

[Cell differentiation of a human bone marrow cell culture under the influence of UHMW-PE debris]

artículo científico publicado en 2005

[Comparative in vitro analysis of vacuum plasma-sprayed titanium implants--evaluation of OPG, Osteokalzin and AP expression]

artículo científico publicado en 2006

[Cytokine profile of a human bone marrow cell culture under the influence of UHMW-PE wear particles]

scientific article published on 01 October 2005

[Histomorphometric evaluation of bone ingrowth of porous titanium by a computer-assisted analyzing system]

scientific article published on 01 December 2005

[Minimally Invasive Stryker-Osteonics unicondylar knee prosthesis with metal-backed tibia component: a 5-year follow-up]

artículo científico publicado en 2005

[Semiquantitative analysis of bone regeneration on porous metallic wire-mesh specimens with or without HA-coating in comparison to pure titanium in animal experiments]

artículo científico publicado en 2002

[Therapy and prevention of infectious diseases]

artículo científico publicado en 2014

Dominio Público Uruguay está sostenido por:

Acerca de Dominio Público Uruguay

Ayuda