Lista de obras - Doreen Cantrell - Dominio Público Uruguay

A new role for the p85-phosphatidylinositol 3-kinase regulatory subunit linking FRAP to p70 S6 kinase activation.

artículo científico publicado en 2001

AMPKα1: a glucose sensor that controls CD8 T-cell memory

artículo científico publicado en 2013

Adenosine-mono-phosphate-activated protein kinase-independent effects of metformin in T cells

artículo científico publicado en 2014

Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice

artículo científico publicado en 2018

Antigen receptor control of methionine metabolism in T cells

scientific article published on 27 March 2019

Antigen receptor regulation of phosphoinositide-dependent kinase 1 pathways during thymocyte development

artículo científico publicado en 2006

Approaches to define antigen receptor-induced serine kinase signal transduction pathways

artículo científico publicado en 2003

Commentary Vav-1 and T cells

scientific article published on 01 April 2003

Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation

artículo científico publicado en 2013

Diacylglycerol and Protein Kinase D Localization during T Lymphocyte Activation ⬇️

Differential regulation of T-cell growth by IL-2 and IL-15

artículo científico publicado en 2006

Differential requirement for RhoA GTPase depending on the cellular localization of protein kinase D.

artículo científico publicado en 2006

Dual phospholipase C/diacylglycerol requirement for protein kinase D1 activation in lymphocytes.

artículo científico publicado en 2004

Environmental and metabolic sensors that control T cell biology

artículo científico

Erratum: Corrigendum: Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation

scholarly article by Linda V Sinclair et al published January 2014 in Nature Immunology

Erratum: Corrigendum: Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking

scholarly article published in Nature Immunology

Essential role for protein kinase D family kinases in the regulation of class II histone deacetylases in B lymphocytes

artículo científico publicado en 2006

Evidence that SHIP-1 contributes to phosphatidylinositol 3,4,5-trisphosphate metabolism in T lymphocytes and can regulate novel phosphoinositide 3-kinase effectors

artículo científico publicado en 2002

Extracellular signal-regulated kinase (ERK) pathway control of CD8+ T cell differentiation

artículo científico publicado en 2020

GTPases and T cell activation

artículo científico publicado en 2003

Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy

artículo científico publicado en 2016

ICOS coreceptor signaling inactivates the transcription factor FOXO1 to promote Tfh cell differentiation.

artículo científico publicado en 2015

Identification of pro-interleukin 16 as a novel target of MAP kinases in activated T lymphocytes

artículo científico publicado en 2004

Integrin regulation by RhoA in thymocytes

artículo científico publicado en 2005

Interleukin (IL)-2 activation of p21ras in murine myeloid cells transfected with human IL-2 receptor β chain

scholarly article by Manuel Izquierdo et al published March 1992 in European Journal of Immunology

Interleukin-2 shapes the cytotoxic T cell proteome and immune environment-sensing programs.

artículo científico publicado en 2018

Intracellular Location and Cell Context-Dependent Function of Protein Kinase D

artículo científico publicado en 2003

LKB1 is essential for the proliferation of T-cell progenitors and mature peripheral T cells

artículo científico publicado en 2010

LKB1 mediates the development of conventional and innate T cells via AMP-dependent kinase autonomous pathways

artículo científico publicado en 2013

Mathematical Models for Immunology: Current State of the Art and Future Research Directions

artículo científico publicado en 2016

Metabolic regulation of hepatitis B immunopathology by myeloid-derived suppressor cells.

artículo científico publicado en 2015

Metabolism, migration and memory in cytotoxic T cells ⬇️

artículo científico publicado el 14 de enero de 2011

Move to metabolism

artículo científico publicado en 2019

New insights into the regulation and function of serine/threonine kinases in T lymphocytes

artículo científico publicado en 2009

Notch-induced T cell development requires phosphoinositide-dependent kinase 1.

artículo científico publicado en 2007

Of Mosaicism and Mechanisms: How JAK1 Goes Awry

scientific article published on 01 September 2020

PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells

artículo científico publicado en 2012

Phenformin, But Not Metformin, Delays Development of T Cell Acute Lymphoblastic Leukemia/Lymphoma via Cell-Autonomous AMPK Activation

article

Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking

artículo científico publicado en 2008

Phosphoinositide (3,4,5)-triphosphate binding to phosphoinositide-dependent kinase 1 regulates a protein kinase B/Akt signaling threshold that dictates T-cell migration, not proliferation

artículo científico publicado en 2009

Phosphoinositide 3-kinase and the mammalian target of rapamycin pathways control T cell migration

scientific article published on January 2010

Phosphoinositide-dependent kinase 1 controls migration and malignant transformation but not cell growth and proliferation in PTEN-null lymphocytes

artículo científico publicado en 2009

Phosphoinositide-dependent kinase l (PDK1) haplo-insufficiency inhibits production of alpha/beta (alpha/beta) but not gamma delta (gamma/delta) T lymphocytes

artículo científico publicado en 2006

Phosphoinositide-dependent protein kinase-1 (PDK1)-independent activation of the protein kinase C substrate, protein kinase D.

artículo científico publicado en 2007

Phosphoproteomic Analyses of Interleukin 2 Signaling Reveal Integrated JAK Kinase-Dependent and -Independent Networks in CD8(+) T Cells

artículo científico publicado en 2016

Phosphoproteomic analysis reveals an intrinsic pathway for the regulation of histone deacetylase 7 that controls the function of cytotoxic T lymphocytes

artículo científico publicado en 2011

Potent and selective chemical probe of hypoxic signalling downstream of HIF-α hydroxylation via VHL inhibition

artículo científico publicado en 2016

Protein kinase B (Akt) regulation and function in T lymphocytes

artículo científico publicado en 2002

Protein kinase B controls transcriptional programs that direct cytotoxic T cell fate but is dispensable for T cell metabolism

artículo científico publicado en 2011

Protein kinase C and beyond

artículo científico publicado en 2004

Protein kinase C mediates platelet secretion and thrombus formation through protein kinase D2

artículo científico publicado en 2011

Protein kinase D enzymes are dispensable for proliferation, survival and antigen receptor-regulated NFkappaB activity in vertebrate B-cells

artículo científico publicado en 2007

Protein kinase D is a downstream target of protein kinase Ctheta

artículo científico publicado en 2002

Protein kinase D isoforms are dispensable for integrin-mediated lymphocyte adhesion and homing to lymphoid tissues

artículo científico publicado en 2012

Protein kinase D2 has a restricted but critical role in T-cell antigen receptor signalling in mature T-cells

artículo científico publicado en 2012

Protein kinase D2 is a digital amplifier of T cell receptor-stimulated diacylglycerol signaling in naïve CD8⁺ T cells

artículo científico

Quantitative analysis of T cell proteomes and environmental sensors during T cell differentiation

artículo científico publicado en 2019

Quantitative analysis of how Myc controls T cell proteomes and metabolic pathways during T cell activation

scientific article published on 05 February 2020

Quantitative phosphoproteomics of cytotoxic T cells to reveal protein kinase d 2 regulated networks.

artículo científico publicado en 2014

Rap1A positively regulates T cells via integrin activation rather than inhibiting lymphocyte signaling

artículo científico publicado en 2002

Regulation and function of serine kinase networks in lymphocytes

artículo científico publicado en 2003

Regulation of an activated S6 kinase 1 variant reveals a novel mammalian target of rapamycin phosphorylation site

artículo científico publicado en 2002

Regulation of the energy sensor AMP-activated protein kinase by antigen receptor and Ca2+ in T lymphocytes.

artículo científico publicado en 2006

Serine-threonine kinases in TCR signaling.

artículo científico publicado en 2014

Signaling and Function of Interleukin-2 in T Lymphocytes.

artículo científico publicado en 2018

Signaling in lymphocyte activation

artículo científico

Single Cell Glucose Uptake Assays: A Cautionary Tale

scientific article published on 17 August 2020

Single cell analysis of kynurenine and System L amino acid transport in T cells.

artículo científico publicado en 2018

Single cell tuning of Myc expression by antigen receptor signal strength and interleukin-2 in T lymphocytes.

artículo científico publicado en 2015

Stimulation of p21 ras upon T-cell activation

artículo científico publicado en 1990

Sustained IL-12 signaling is required for Th1 development

artículo científico publicado en 2004

Sustained and dynamic inositol lipid metabolism inside and outside the immunological synapse

artículo científico publicado en 2002

T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR.

artículo científico publicado en 2008

T-cell antigen receptor signal transduction

Temporal differences in the dependency on phosphoinositide-dependent kinase 1 distinguish the development of invariant Valpha14 NKT cells and conventional T cells

artículo científico publicado en 2010

The BAFF receptor transduces survival signals by co-opting the B cell receptor signaling pathway.

artículo científico publicado en 2013

The Coordination of T-cell Function by Serine/Threonine Kinases ⬇️

artículo científico publicado el 1 de enero de 2011

The active inner life of naive T cells

artículo científico publicado en 2020

The cytotoxic T cell proteome and its shaping by the kinase mTOR.

artículo científico publicado en 2015

The impact of KLF2 modulation on the transcriptional program and function of CD8 T cells

artículo científico publicado en 2013

The role of serine/threonine kinases in T-cell activation

artículo científico publicado en 2006

The serine kinase phosphoinositide-dependent kinase 1 (PDK1) regulates T cell development

artículo científico publicado en 2004

Transgenic analysis of thymocyte signal transduction

artículo científico publicado en 2002

Unique functions for protein kinase D1 and protein kinase D2 in mammalian cells

scientific journal article

Lista de obras de Doreen Cantrell

A new role for the p85-phosphatidylinositol 3-kinase regulatory subunit linking FRAP to p70 S6 kinase activation.

AMPKα1: a glucose sensor that controls CD8 T-cell memory

Adenosine-mono-phosphate-activated protein kinase-independent effects of metformin in T cells

Amino acid-dependent cMyc expression is essential for NK cell metabolic and functional responses in mice

Antigen receptor control of methionine metabolism in T cells

Antigen receptor regulation of phosphoinositide-dependent kinase 1 pathways during thymocyte development

Approaches to define antigen receptor-induced serine kinase signal transduction pathways

Commentary Vav-1 and T cells

Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation

Diacylglycerol and Protein Kinase D Localization during T Lymphocyte Activation ⬇️

Differential regulation of T-cell growth by IL-2 and IL-15

Differential requirement for RhoA GTPase depending on the cellular localization of protein kinase D.

Dual phospholipase C/diacylglycerol requirement for protein kinase D1 activation in lymphocytes.

Environmental and metabolic sensors that control T cell biology

Erratum: Corrigendum: Control of amino-acid transport by antigen receptors coordinates the metabolic reprogramming essential for T cell differentiation

Erratum: Corrigendum: Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking

Essential role for protein kinase D family kinases in the regulation of class II histone deacetylases in B lymphocytes

Evidence that SHIP-1 contributes to phosphatidylinositol 3,4,5-trisphosphate metabolism in T lymphocytes and can regulate novel phosphoinositide 3-kinase effectors

Extracellular signal-regulated kinase (ERK) pathway control of CD8+ T cell differentiation

GTPases and T cell activation

Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy

ICOS coreceptor signaling inactivates the transcription factor FOXO1 to promote Tfh cell differentiation.

Identification of pro-interleukin 16 as a novel target of MAP kinases in activated T lymphocytes

Integrin regulation by RhoA in thymocytes

Interleukin (IL)-2 activation of p21ras in murine myeloid cells transfected with human IL-2 receptor β chain

Interleukin-2 shapes the cytotoxic T cell proteome and immune environment-sensing programs.

Intracellular Location and Cell Context-Dependent Function of Protein Kinase D

LKB1 is essential for the proliferation of T-cell progenitors and mature peripheral T cells

LKB1 mediates the development of conventional and innate T cells via AMP-dependent kinase autonomous pathways

Mathematical Models for Immunology: Current State of the Art and Future Research Directions

Metabolic regulation of hepatitis B immunopathology by myeloid-derived suppressor cells.

Metabolism, migration and memory in cytotoxic T cells ⬇️

Move to metabolism

New insights into the regulation and function of serine/threonine kinases in T lymphocytes

Notch-induced T cell development requires phosphoinositide-dependent kinase 1.

Of Mosaicism and Mechanisms: How JAK1 Goes Awry

PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells

Phenformin, But Not Metformin, Delays Development of T Cell Acute Lymphoblastic Leukemia/Lymphoma via Cell-Autonomous AMPK Activation

Phosphatidylinositol-3-OH kinase and nutrient-sensing mTOR pathways control T lymphocyte trafficking

Phosphoinositide (3,4,5)-triphosphate binding to phosphoinositide-dependent kinase 1 regulates a protein kinase B/Akt signaling threshold that dictates T-cell migration, not proliferation

Phosphoinositide 3-kinase and the mammalian target of rapamycin pathways control T cell migration

Phosphoinositide-dependent kinase 1 controls migration and malignant transformation but not cell growth and proliferation in PTEN-null lymphocytes

Phosphoinositide-dependent kinase l (PDK1) haplo-insufficiency inhibits production of alpha/beta (alpha/beta) but not gamma delta (gamma/delta) T lymphocytes

Phosphoinositide-dependent protein kinase-1 (PDK1)-independent activation of the protein kinase C substrate, protein kinase D.

Phosphoproteomic Analyses of Interleukin 2 Signaling Reveal Integrated JAK Kinase-Dependent and -Independent Networks in CD8(+) T Cells

Phosphoproteomic analysis reveals an intrinsic pathway for the regulation of histone deacetylase 7 that controls the function of cytotoxic T lymphocytes

Potent and selective chemical probe of hypoxic signalling downstream of HIF-α hydroxylation via VHL inhibition

Protein kinase B (Akt) regulation and function in T lymphocytes

Protein kinase B controls transcriptional programs that direct cytotoxic T cell fate but is dispensable for T cell metabolism

Protein kinase C and beyond

Protein kinase C mediates platelet secretion and thrombus formation through protein kinase D2

Protein kinase D enzymes are dispensable for proliferation, survival and antigen receptor-regulated NFkappaB activity in vertebrate B-cells

Protein kinase D is a downstream target of protein kinase Ctheta

Protein kinase D isoforms are dispensable for integrin-mediated lymphocyte adhesion and homing to lymphoid tissues

Protein kinase D2 has a restricted but critical role in T-cell antigen receptor signalling in mature T-cells

Protein kinase D2 is a digital amplifier of T cell receptor-stimulated diacylglycerol signaling in naïve CD8⁺ T cells

Quantitative analysis of T cell proteomes and environmental sensors during T cell differentiation

Quantitative analysis of how Myc controls T cell proteomes and metabolic pathways during T cell activation

Quantitative phosphoproteomics of cytotoxic T cells to reveal protein kinase d 2 regulated networks.

Rap1A positively regulates T cells via integrin activation rather than inhibiting lymphocyte signaling

Regulation and function of serine kinase networks in lymphocytes

Regulation of an activated S6 kinase 1 variant reveals a novel mammalian target of rapamycin phosphorylation site

Regulation of the energy sensor AMP-activated protein kinase by antigen receptor and Ca2+ in T lymphocytes.

Serine-threonine kinases in TCR signaling.

Signaling and Function of Interleukin-2 in T Lymphocytes.

Signaling in lymphocyte activation

Single Cell Glucose Uptake Assays: A Cautionary Tale

Single cell analysis of kynurenine and System L amino acid transport in T cells.

Single cell tuning of Myc expression by antigen receptor signal strength and interleukin-2 in T lymphocytes.

Stimulation of p21 ras upon T-cell activation

Sustained IL-12 signaling is required for Th1 development

Sustained and dynamic inositol lipid metabolism inside and outside the immunological synapse

T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR.

T-cell antigen receptor signal transduction

Temporal differences in the dependency on phosphoinositide-dependent kinase 1 distinguish the development of invariant Valpha14 NKT cells and conventional T cells

The BAFF receptor transduces survival signals by co-opting the B cell receptor signaling pathway.

The Coordination of T-cell Function by Serine/Threonine Kinases ⬇️

The active inner life of naive T cells

The cytotoxic T cell proteome and its shaping by the kinase mTOR.