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Lista de obras de Heike Mertsching

'Human-on-a-chip' developments: a translational cutting-edge alternative to systemic safety assessment and efficiency evaluation of substances in laboratory animals and man?

artículo científico

* An Injectable Recombinant Collagen I Peptide-Based Macroporous Microcarrier Allows Superior Expansion of C2C12 and Human Bone Marrow-Derived Mesenchymal Stromal Cells and Supports Deposition of Mineralized Matrix

artículo científico publicado en 2017

A Combined 3D Tissue Engineered In Vitro/In Silico Lung Tumor Model for Predicting Drug Effectiveness in Specific Mutational Backgrounds

artículo científico publicado en 2016

A bioreactor system for interfacial culture and physiological perfusion of vascularized tissue equivalents

artículo científico publicado en 2012

A coculture system composed of THP-1 cells and 3D reconstructed human epidermis to assess activation of dendritic cells by sensitizing chemicals after topical exposure

scientific article published on 14 February 2019

A combined tissue engineered / in silico signature tool for patient stratification in lung cancer

artículo científico publicado en 2018

A comparative multi-parametric in vitro model identifies the power of test conditions to predict the fibrotic tendency of a biomaterial

artículo científico publicado en 2017

A first vascularized skin equivalent as an alternative to animal experimentation

artículo científico publicado en 2016

A human in vitro model that mimics the renal proximal tubule

artículo científico publicado en 2014

A multifunctional bioreactor for three-dimensional cell (co)-culture

artículo científico publicado en 2005

A novel small-animal model for accelerated investigation of tissue-engineered aortic valve conduits

artículo científico publicado en 2010

A perfusion bioreactor system efficiently generates cell-loaded bone substitute materials for addressing critical size bone defects

artículo científico publicado en 2015

A standardized method based on pigmented epidermal models evaluates sensitivity against UV-irradiation

artículo científico publicado en 2018

A three-dimensional intestinal tissue model reveals factors and small regulatory RNAs important for colonization with Campylobacter jejuni

scientific article published on 18 February 2020

A versatile modular bioreactor platform for Tissue Engineering

artículo científico publicado en 2016

Acellular Scaffold Implantation – No Alternative to Tissue Engineering ⬇️

artículo científico publicado el 1 de marzo de 2003

Activation of Myenteric Glia during Acute Inflammation In Vitro and In Vivo

artículo científico publicado en 2016

Advanced Therapy Medicinal Products: A Guide for Bone Marrow-derived MSC Application in Bone and Cartilage Tissue Engineering

artículo científico publicado en 2017

Altered pancreatic islet morphology and function in SGLT1 knockout mice on a glucose-deficient, fat-enriched diet

artículo científico publicado en 2018

Alternative methods for the replacement of eye irritation testing

artículo científico publicado en 2015

Ammonia plasma treatment of polystyrene surfaces enhances proliferation of primary human mesenchymal stem cells and human endothelial cells

artículo científico publicado en 2012

An Advanced Human Intestinal Coculture Model Reveals Compartmentalized Host and Pathogen Strategies during Salmonella Infection

artículo científico publicado en 2020

An adherent mucus layer attenuates the genotoxic effect of colibactin

artículo científico publicado en 2017

An engineered 3D human airway mucosa model based on an SIS scaffold

artículo científico publicado en 2014

An in vitro model mimics the contact of biomaterials to blood components and the reaction of surrounding soft tissue

artículo científico publicado en 2019

Androgen and estrogen receptors in the human corpus cavernosum penis: immunohistochemical and cell culture results ⬇️

artículo científico publicado el 29 de octubre de 2003

Applicability of second-generation upcyte® human hepatocytes for use in CYP inhibition and induction studies

artículo científico publicado en 2015

Automated real-time monitoring of human pluripotent stem cell aggregation in stirred tank reactors

scientific article published on 23 August 2019

Biological vascularized matrix for bladder tissue engineering: matrix preparation, reseeding technique and short-term implantation in a porcine model

artículo científico publicado en 2005

Biomimetic Human Tissue Model for Long-Term Study of Neisseria gonorrhoeae Infection

artículo científico publicado en 2019

Biomimetic in vitro test system for evaluation of dental implant materials

artículo científico publicado en 2020

Bioreactors in tissue engineering - principles, applications and commercial constraints

artículo científico publicado en 2012

Bone tissue engineering in osteoporosis

artículo científico

Calcium fluoride based multifunctional nanoparticles for multimodal imaging

artículo científico publicado en 2017

Ciclopirox olamine promotes the angiogenic response of endothelial cells and mesenchymal stem cells

artículo científico publicado en 2019

Clinical application of tissue engineered human heart valves using autologous progenitor cells

artículo científico publicado en 2006

Commensal and pathogenic biofilms differently modulate peri-implant oral mucosa in an organotypic model

scientific article published on 17 July 2019

Connecting Cancer Pathways to Tumor Engines: A Stratification Tool for Colorectal Cancer Combining Human In Vitro Tissue Models with Boolean In Silico Models

scientific article published on 20 December 2019

Construction of autologous human heart valves based on an acellular allograft matrix.

artículo científico publicado en 2002

Corrigendum: Rapid Analysis of Cell-Nanoparticle Interactions using Single-Cell Raman Trapping Microscopy

artículo científico publicado en 2018

Could 37 degrees C storage temperature extend homovital valve allograft viability?

scientific article published on 01 May 2004

Cross-linked Collagen Hydrogel Matrix Resisting Contraction To Facilitate Full-Thickness Skin Equivalents.

artículo científico publicado en 2017

Cytotoxicity of different intracavernous vasoactive drugs on cultured endothelial cells of human corpus cavernosum penis

artículo científico publicado en 2004

Deformation strain is the main physical driver for skeletal precursors to undergo osteogenesis in earlier stages of osteogenic cell maturation

artículo científico publicado en 2017

Development of 3D human intestinal equivalents for substance testing in microliter-scale on a multi-organ-chip

artículo científico publicado en 2013

Development of Human Salivary Gland-Like Tissue In Vitro.

artículo científico publicado en 2017

Development of a bioreactor-system for pre-endothelialized cardiac patch generation with enhanced viscoelastic properties by combined collagen I compression and stromal cell culture

artículo científico publicado en 2020

Development of a human three-dimensional organotypic skin-melanoma spheroid model for in vitro drug testing ⬇️

artículo científico publicado el 11 de julio de 2013

Development of an Advanced Primary Human In Vitro Model of the Small Intestine

artículo científico publicado en 2016

Differential Regulation of SOX9 Protein During Chondrogenesis of Induced Pluripotent Stem Cells Versus Mesenchymal Stromal Cells: A Shortcoming for Cartilage Formation

artículo científico publicado en 2016

Dynamic cultivation of human stem cells under physiological conditions.

artículo científico publicado en 2015

EZH2 Inhibition in Ewing Sarcoma Upregulates GD2 Expression for Targeting with Gene-Modified T Cells

artículo científico publicado en 2019

Editorial: Strategies in tissue engineering and regenerative medicine ⬇️

artículo científico publicado el 1 de marzo de 2013

Electrospun poly(D/L-lactide-co-L-lactide) hybrid matrix: a novel scaffold material for soft tissue engineering

artículo científico publicado en 2010

Engineered liver-like tissue on a capillarized matrix for applied research

artículo científico publicado en 2007

Engineering of a vascularized scaffold for artificial tissue and organ generation

artículo científico publicado en 2005

Establishment of a Human Blood-Brain Barrier Co-culture Model Mimicking the Neurovascular Unit Using Induced Pluri- and Multipotent Stem Cells.

artículo científico publicado en 2017

Establishment of a human 3D lung cancer model based on a biological tissue matrix combined with a Boolean in silico model

artículo científico publicado en 2013

Europe's advanced therapy medicinal products: chances and challenges

artículo científico publicado en 2009

Evaluation of a Miniaturized Biologically Vascularized Scaffold in vitro and in vivo

artículo científico publicado en 2018

Ex vivo culture platform for assessment of cartilage repair treatment strategies.

artículo científico publicado en 2016

Expansion of chondrocytes in a three-dimensional matrix for tracheal tissue engineering

artículo científico publicado en 2004

Experimental generation of a tissue-engineered functional and vascularized trachea.

artículo científico publicado en 2004

Experimental tracheal patching using extracellular matrix scaffolds

artículo científico publicado en 2009

Expression of epidermal growth-factor receptor in lymphangiomatosis: a new therapeutic target?

artículo científico publicado en 2004

Feasibility Study on a Microwave-Based Sensor for Measuring Hydration Level Using Human Skin Models

artículo científico publicado en 2016

First human transplantation of a bioengineered airway tissue

artículo científico publicado en 2004

Follistatin Effects in Migration, Vascularization, and Osteogenesis in vitro and Bone Repair in vivo

Functional neointima characterization of vascular prostheses in human

artículo científico publicado en 2004

Functional tissue engineering of autologous tunica albuginea: a possible graft for Peyronie's disease surgery

artículo científico publicado en 2004

Generation and transplantation of an autologous vascularized bioartificial human tissue

artículo científico publicado en 2009

Generation of a three-dimensional full thickness skin equivalent and automated wounding

artículo científico publicado en 2015

Guided tissue regeneration: porcine matrix does not transmit PERV.

artículo científico publicado en 2004

Host-integration of a tissue-engineered airway patch: two-year follow-up in a single patient

artículo científico publicado en 2014

Human Organotypic Lung Tumor Models: Suitable For Preclinical 18F-FDG PET-Imaging

artículo científico publicado en 2016

Human barrier models for the in vitro assessment of drug delivery

artículo científico publicado en 2016

Human skin equivalent as an alternative to animal testing

artículo científico publicado en 2008

Impedance spectroscopy for the non-destructive evaluation of in vitro epidermal models

artículo científico publicado en 2014

In Vitro Generation of Functional Liver Organoid-Like Structures Using Adult Human Cells

artículo científico publicado en 2015

In situ guided tissue regeneration in musculoskeletal diseases and aging : Implementing pathology into tailored tissue engineering strategies

artículo científico publicado en 2012

In vitro chemotaxis and tissue remodeling assays quantitatively characterize foreign body reaction

artículo científico publicado en 2016

In vitro viability of human cavernosal endothelial and fibroblastic cells after exposure to papaverine/phentolamine and prostaglandin E1.

artículo científico publicado en 2005

In vivo model for cross-species porcine endogenous retrovirus transmission using tissue engineered pulmonary arteries

artículo científico publicado en 2003

In vivo repopulation of xenogeneic and allogeneic acellular valve matrix conduits in the pulmonary circulation

artículo científico publicado en 2003

Inflammation-induced tissue damage mimicking GvHD in human skin models as test-platform for immunotherapeutics

scientific article published on 14 April 2020

Influence of scaffold thickness and scaffold composition on bioartificial graft survival

artículo científico publicado en 2003

Inhibitor of Apoptosis Protein-1 Regulates Tumor Necrosis Factor-Mediated Destruction of Intestinal Epithelial Cells

artículo científico publicado en 2016

Integrating biological vasculature into a multi-organ-chip microsystem

artículo científico publicado en 2013

Interactions of donor sources and media influence the histo-morphological quality of full-thickness skin models

artículo científico publicado en 2016

Investigation of Migration and Differentiation of Human Mesenchymal Stem Cells on Five-Layered Collagenous Electrospun Scaffold Mimicking Native Cartilage Structure

artículo científico publicado en 2016

Is chronic graft rejection the reason for degenerative changes in allogeneic and xenogeneic heart valve prostheses: immunohistochemical evaluation of inflammatory factors

artículo científico publicado en 2002

Isolation of primary endothelial and stromal cell cultures of the corpus cavernosum penis for basic research and tissue engineering

artículo científico publicado en 2005

Isotropic Versus Bipolar Functionalized Biomimetic Artificial Basement Membranes and Their Evaluation in Long-Term Human Cell Co-Culture

artículo científico publicado en 2016

Linking two worlds in polymer chemistry: The influence of block uniformity and dispersity in amphiphilic block copolypeptoids on their self-assembly

scientific article published on 07 February 2019

Matrix decoded - A pancreatic extracellular matrix with organ specific cues guiding human iPSC differentiation

artículo científico publicado en 2020

Mimicking Metastases Including Tumor Stroma: A New Technique to Generate a Three-Dimensional Colorectal Cancer Model Based on a Biological Decellularized Intestinal Scaffold

artículo científico publicado en 2016

Nanotopographical Coatings Induce an Early Phenotype-Specific Response of Primary Material-Resident M1 and M2 Macrophages

scientific article published on 04 March 2020

Nell-1, HMGB1 and CCN2 enhance migration and vasculogenesis, but not osteogenic differentiation compared to BMP2.

artículo científico publicado en 2017

Non-Coding RNAs in Lung Cancer: Contribution of Bioinformatics Analysis to the Development of Non-Invasive Diagnostic Tools

artículo científico publicado en 2016

Non-animal models of epithelial barriers (skin, intestine and lung) in research, industrial applications and regulatory toxicology.

artículo científico publicado en 2015

Non-contact, label-free monitoring of cells and extracellular matrix using Raman spectroscopy

artículo científico publicado en 2012

Obstructed defecation-an enteric neuropathy? An exploratory study of patient samples

artículo científico publicado en 2018

Oligonucleotide and Parylene Surface Coating of Polystyrene and ePTFE for Improved Endothelial Cell Attachment and Hemocompatibility

artículo científico publicado en 2012

Osteogenesis and mineralization of mesenchymal stem cells in collagen type I-based recombinant peptide scaffolds

artículo científico publicado en 2017

Physical contact between mesenchymal stem cells and endothelial precursors induces distinct signatures with relevance to the very early phase of regeneration

artículo científico publicado en 2018

Porcine endogenous retrovirus released by a bioartificial liver infects primary human cells

artículo científico publicado en 2009

Preclinical Assessment of a Tissue-Engineered Vasomotive Human Small-Calibered Vessel Based on a Decellularized Xenogenic Matrix: Histological and Functional Characterization ⬇️

artículo científico publicado el 3 de febrero de 2011

Preparation of a Three-Dimensional Full Thickness Skin Equivalent

artículo científico publicado en 2017

ROR1-CAR T cells are effective against lung and breast cancer in advanced microphysiologic 3D tumor models

artículo científico publicado en 2019

Raman Spectroscopy: A Noninvasive Analysis Tool for the Discrimination of Human Skin Cells

artículo científico publicado en 2011

Raman spectroscopy as a tool for quality and sterility analysis for tissue engineering applications like cartilage transplants.

artículo científico publicado en 2010

Raman spectroscopy for the non-contact and non-destructive monitoring of collagen damage within tissues

artículo científico publicado en 2011

Rapid Analysis of Cell-Nanoparticle Interactions using Single-Cell Raman Trapping Microscopy.

artículo científico publicado en 2018

Recombinant Collagen I Peptide Microcarriers for Cell Expansion and Their Potential Use As Cell Delivery System in a Bioreactor Model

artículo científico publicado en 2018

Reepithelialization in focus: Non-invasive monitoring of epidermal wound healing in vitro

scientific article published on 01 August 2019

Regulatory-Compliant Validation of a Highly Sensitive qPCR for Biodistribution Assessment of Hemophilia A Patient Cells

artículo científico publicado en 2020

Replacement of the trachea with an autologous aortic graft

scientific article published on 01 September 2004

Replacing the Draize eye test: Impedance spectroscopy as a 3R method to discriminate between all GHS categories for eye irritation

artículo científico publicado en 2018

Role of inflammation in allogeneic and xenogeneic heart valve degeneration: immunohistochemical evaluation of inflammatory endothelial cell activation

artículo científico publicado en 2003

Schedule-dependent antagonism of paclitaxel and cisplatin in human gastric and ovarian carcinoma cell Lines in vitro ⬇️

artículo científico publicado el 1 de enero de 1995

Screening Applications to Test Cellular Fitness in Transwell® Models After Nanoparticle Treatment

artículo científico publicado en 2017

Session 10: Biofilms Implant related infections

scientific article published on 01 February 2019

Session 9: Biomaterials -Elektrospinning

scientific article published on 01 February 2019

Site-Directed Immobilization of Bone Morphogenetic Protein 2 to Solid Surfaces by Click Chemistry

artículo científico publicado en 2018

Spin echo based cardiac diffusion imaging at 7T: An ex vivo study of the porcine heart at 7T and 3T

artículo científico publicado en 2019

Stem cell labeling with iron oxide nanoparticles: impact of 3D culture on cell labeling maintenance

artículo científico publicado en 2016

Stem cell microenvironments--unveiling the secret of how stem cell fate is defined

artículo científico publicado en 2010

Stem cell- and growth factor-based regenerative therapies for avascular necrosis of the femoral head

artículo científico publicado en 2012

Strategies and First Advances in the Development of Prevascularized Bone Implants

artículo científico publicado en 2016

Structure-Function relationships of equine menisci.

artículo científico publicado en 2018

The physiological performance of a three-dimensional model that mimics the microenvironment of the small intestine

artículo científico publicado en 2011

The potential of bioartificial tissues in oncology research and treatment

artículo científico publicado en 2007

Three-Dimensional Coculture of Meniscal Cells and Mesenchymal Stem Cells in Collagen Type I Hydrogel on a Small Intestinal Matrix-A Pilot Study Toward Equine Meniscus Tissue Engineering

artículo científico publicado en 2017

Tissue Engineering Human Small‐Caliber Autologous Vessels Using a Xenogenous Decellularized Connective Tissue Matrix Approach: Preclinical Comparative Biomechanical Studies ⬇️

artículo científico publicado el 7 de julio de 2011

Tissue Mimicry in Morphology and Composition Promotes Hierarchical Matrix Remodeling of Invading Stem Cells in Osteochondral and Meniscus Scaffolds

artículo científico publicado en 2018

Tissue engineering of a human 3D in vitro tumor test system

artículo científico publicado en 2013

Tissue engineering of viable pulmonary arteries for surgical correction of congenital heart defects

artículo científico publicado en 2006

Tissue remodeling in a bioartificial fibromuscular patch following transplantation in a human

artículo científico publicado en 2005

Track I. Cellular-, Tissue- and Bioengineering

artículo científico publicado en 2016

Upcyte® microvascular endothelial cells repopulate decellularized scaffold

artículo científico publicado en 2012

Vascularised human tissue models: a new approach for the refinement of biomedical research

artículo científico publicado en 2010

[Differentiation potential of human stem cells--approaches to tissue engineering and to cell transplantation]

scientific article published on 01 July 2002

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