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Lista de obras de Jan Hoeijmakers

2-Acetylaminofluorene-modified probes for the indirect hybridocytochemical detection of specific nucleic acid sequences ⬇️

artículo científico publicado el 1 de julio de 1984

A 3' --> 5' XPB helicase defect in repair/transcription factor TFIIH of xeroderma pigmentosum group B affects both DNA repair and transcription

artículo científico publicado en 1996

A human and mouse homolog of the Schizosaccharomyces pombe rad1+ cell cycle checkpoint control gene

artículo científico publicado en 1998

A long-range restriction map of the human chromosome 19q13 region: close physical linkage between CKMM and the ERCC1 and ERCC2 genes

artículo científico publicado en 1990

A mouse model for the basal transcription/DNA repair syndrome trichothiodystrophy

scientific journal article

A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis

artículo científico publicado en 2006

A new, tenth subunit of TFIIH is responsible for the DNA repair syndrome trichothiodystrophy group A

artículo científico publicado en 2004

A novel regulation mechanism of DNA repair by damage-induced and RAD23-dependent stabilization of xeroderma pigmentosum group C protein

artículo científico publicado en 2003

A presumed DNA helicase encoded by ERCC-3 is involved in the human repair disorders xeroderma pigmentosum and Cockayne's syndrome

artículo científico publicado en 1990

A variant surface glycoprotein of Trypanosoma brucei synthesized with a C-terminal hydrophobic 'tail' absent from purified glycoprotein.

artículo científico publicado en 1980

ATP-dependent chromatin remodeling by the Cockayne syndrome B DNA repair-transcription-coupling factor.

artículo científico publicado en 2000

Adaptive stress response in segmental progeria resembles long-lived dwarfism and calorie restriction in mice

artículo científico publicado en 2006

Age-related skeletal dynamics and decrease in bone strength in DNA repair deficient male trichothiodystrophy mice

artículo científico publicado en 2012

Aging and genome maintenance: lessons from the mouse?

artículo científico publicado en 2003

Altered lipid metabolism in the aging kidney identified by three layered omic analysis

artículo científico publicado en 2016

Augmentation of protein production by a combination of the T7 RNA polymerase system and ubiquitin fusion: overproduction of the human DNA repair protein, ERCC1, as a ubiquitin fusion protein in Escherichia coli.

artículo científico

Base excision repair deficient mice lacking the Aag alkyladenine DNA glycosylase.

artículo científico publicado en 1997

Biochemical and biological characterization of wild-type and ATPase-deficient Cockayne syndrome B repair protein.

artículo científico publicado en 1998

Ca2+ toxicity due to reverse Na+/Ca2+ exchange contributes to degeneration of neurites of DRG neurons induced by a neuropathy-associated Nav1.7 mutation

artículo científico publicado en 2015

Cell type-specific hypersensitivity to oxidative damage in CSB and XPA mice

scientific journal article

Cell-autonomous progeroid changes in conditional mouse models for repair endonuclease XPG deficiency

artículo científico publicado en 2014

Characterization of kinetoplast DNA networks from the insect trypanosome Crithidia luciliae

artículo científico publicado el 20 de septiembre de 1977

Characterization of mRAD18Sc, a mouse homolog of the yeast postreplication repair gene RAD18

scientific journal article

Characterization of the mouse homolog of the XPBC/ERCC-3 gene implicated in xeroderma pigmentosum and Cockayne's syndrome

scientific journal article

Chromosomal stability and the DNA double-stranded break connection

artículo científico publicado en 2001

Clinical heterogeneity within xeroderma pigmentosum associated with mutations in the DNA repair and transcription gene ERCC3

artículo científico publicado en 1994

Cloning and characterization of p52, the fifth subunit of the core of the transcription/DNA repair factor TFIIH

artículo científico publicado en 1997

Cloning and characterization of the Drosophila homolog of the xeroderma pigmentosum complementation-group B correcting gene, ERCC3.

artículo científico publicado en 1992

Cloning of a human homolog of the yeast nucleotide excision repair gene MMS19 and interaction with transcription repair factor TFIIH via the XPB and XPD helicases

artículo científico publicado en 2000

Cloning of human and mouse genes homologous to RAD52, a yeast gene involved in DNA repair and recombination

artículo científico publicado en 1994

Cloning, comparative mapping, and RNA expression of the mouse homologues of the Saccharomyces cerevisiae nucleotide excision repair gene RAD23

scientific journal article

Cockayne syndrome: defective repair of transcription? ⬇️

artículo científico publicado el 16 de julio de 1997

Complementation group assignments of moderately UV-sensitive CHO mutants isolated by large-scale screening (FAECB)

artículo científico publicado en 1994

Conserved pattern of antisense overlapping transcription in the homologous human ERCC-1 and yeast RAD10 DNA repair gene regions

artículo científico publicado en 1989

Correction of the DNA repair defect in xeroderma pigmentosum group E by injection of a DNA damage-binding protein

artículo científico publicado en 1994

Correction of xeroderma pigmentosum repair defect by basal transcription factor BTF2 (TFIIH)

artículo científico publicado en 1994

DNA Damage, Aging, and Cancer

artículo científico publicado en 2009

DNA damage triggers nucleotide excision repair-dependent monoubiquitylation of histone H2A

artículo científico publicado en 2006

DNA damage-induced histone H1 ubiquitylation is mediated by HUWE1 and stimulates the RNF8-RNF168 pathway.

artículo científico publicado en 2017

DNA rearrangements involving the genes for variant antigens in Trypanosoma brucei

artículo científico publicado en 1981

DNA repair and ultraviolet mutagenesis in cells from a new patient with xeroderma pigmentosum group G and cockayne syndrome resemble xeroderma pigmentosum cells

artículo científico publicado en 1996

DNA repair methyltransferase (Mgmt) knockout mice are sensitive to the lethal effects of chemotherapeutic alkylating agents

artículo científico publicado en 1999

DNA structural elements required for ERCC1-XPF endonuclease activity.

artículo científico publicado en 1998

DNA-binding polarity of human replication protein A positions nucleases in nucleotide excision repair

scientific journal article

Defective transcription-coupled repair in Cockayne syndrome B mice is associated with skin cancer predisposition

scientific journal article

Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age

scientific journal article

Delayed and accelerated aging share common longevity assurance mechanisms

artículo científico publicado en 2008

Deletion of the nucleotide excision repair gene Ercc1 reduces immunoglobulin class switching and alters mutations near switch recombination junctions

scientific journal article

Developmental defects and male sterility in mice lacking the ubiquitin-like DNA repair gene mHR23B

artículo científico publicado en 2002

Dhr6, a Drosophila homolog of the yeast DNA-repair gene RAD6.

artículo científico publicado en 1991

Differences between rodent and human cell lines in the amount of integrated DNA after transfection

scientific article published on 01 March 1987

Different effects of CSA and CSB deficiency on sensitivity to oxidative DNA damage

scientific journal article

Differential role of basal keratinocytes in UV-induced immunosuppression and skin cancer

artículo científico publicado en 2006

Differentiation driven changes in the dynamic organization of Basal transcription initiation

artículo científico publicado en 2009

Dimerization and nuclear entry of mPER proteins in mammalian cells

artículo científico publicado en 2000

Disruption of TTDA results in complete nucleotide excision repair deficiency and embryonic lethality

artículo científico publicado en 2013

Disruption of mouse ERCC1 results in a novel repair syndrome with growth failure, nuclear abnormalities and senescence

scientific journal article

Disruption of mouse SNM1 causes increased sensitivity to the DNA interstrand cross-linking agent mitomycin C

artículo científico publicado en 2000

Dynamic interaction of TTDA with TFIIH is stabilized by nucleotide excision repair in living cells

artículo científico publicado en 2006

ERCC1-XPF endonuclease facilitates DNA double-strand break repair

artículo científico publicado en 2008

ERCC1/XPF removes the 3' overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomes

artículo científico publicado en 2003

ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genes

artículo científico publicado el 11 de diciembre de 1992

Early postnatal ataxia and abnormal cerebellar development in mice lacking Xeroderma pigmentosum Group A and Cockayne syndrome Group B DNA repair genes

artículo científico publicado en 2001

Efficient cDNA cloning by direct phenotypic correction of a mutant human cell line (HPRT−) using an Epstein - Barr virus-derived cDNA expression vector ⬇️

artículo científico publicado el 25 de septiembre de 1991

Evolution and mutagenesis of the mammalian excision repair gene ERCC-1

artículo científico publicado en 1988

Expression of the ubiquitin-conjugating DNA repair enzymes HHR6A and B suggests a role in spermatogenesis and chromatin modification.

artículo científico publicado en 1996

First reported patient with human ERCC1 deficiency has cerebro-oculo-facio-skeletal syndrome with a mild defect in nucleotide excision repair and severe developmental failure

artículo científico publicado en 2007

Fluorescence correlation spectroscopy of the binding of nucleotide excision repair protein XPC-hHr23B with DNA substrates

artículo científico publicado en 2008

From xeroderma pigmentosum to the biological clock contributions of Dirk Bootsma to human genetics

artículo científico publicado en 2001

Genome maintenance mechanisms for preventing cancer

artículo científico publicado en 2001

Genomic characterization of the human DNA excision repair gene ERCC-1

artículo científico publicado en 1987

Histone ubiquitination and chromatin remodeling in mouse spermatogenesis.

artículo científico publicado en 1999

Homeostatic imbalance between apoptosis and cell renewal in the liver of premature aging Xpd mice

scientific journal article

Homologous and non-homologous recombination differentially affect DNA damage repair in mice

artículo científico publicado en 2000

How Relevant is the Escherichia coli UvrABC Model for Excision Repair in Eukaryotes? ⬇️

artículo científico publicado el 1 de diciembre de 1991

Human RAD18 interacts with ubiquitylated chromatin components and facilitates RAD9 recruitment to DNA double strand breaks

artículo científico publicado en 2011

Human and mouse homologs of the Saccharomyces cerevisiae RAD54 DNA repair gene: evidence for functional conservation

artículo científico publicado en 1996

Human and mouse homologs of the Schizosaccharomyces pombe rad17+ cell cycle checkpoint control gene

artículo científico publicado en 1999

Hybridocytochemistry with 2-acetylaminofluorene-modified probes

artículo científico publicado en 1984

Inactivation of the HR6B ubiquitin-conjugating DNA repair enzyme in mice causes male sterility associated with chromatin modification.

artículo científico publicado en 1996

Interaction of hHR23 with S5a. The ubiquitin-like domain of hHR23 mediates interaction with S5a subunit of 26 S proteasome

artículo científico publicado en 1999

Involvement of global genome repair, transcription coupled repair, and chromatin remodeling in UV DNA damage response changes during development

artículo científico publicado en 2010

Isolation and characterization of kinetoplast DNA from bloodstream form of Trypanosoma brucei

artículo científico publicado en 1978

Kinetoplast DNA ⬇️

artículo científico publicado el 1 de enero de 1979

Kinetoplast DNA in the insect trypanosomes Crithidia luciliae and Crithidia fasciculata. I. Sequence evolution and transcription of the maxicircle

scientific article published on 01 May 1982

Knockout mouse model and gametogenic failure

scientific journal article

Localization of the nucleotide excision repair gene ERCC6 to human chromosome 10q11-q21

artículo científico publicado el 1 de abril de 1992

Localization of the xeroderma pigmentosum group B-correcting gene ERCC3 to human chromosome 2q21

artículo científico publicado en 1991

Localization of two human homologs, HHR6A and HHR6B, of the yeast DNA repair gene RAD6 to chromosomes Xq24-q25 and 5q23-q31

artículo científico publicado el 1 de marzo de 1992

Loss of HR6B ubiquitin-conjugating activity results in damaged synaptonemal complex structure and increased crossing-over frequency during the male meiotic prophase

artículo científico publicado en 2003

MARK-AGE biomarkers of ageing

artículo científico publicado en 2015

Mammalian Cry1 and Cry2 are essential for maintenance of circadian rhythms

scientific journal article

Mammalian nucleotide excision repair

artículo científico publicado en 1995

Mapping of interaction domains between human repair proteins ERCC1 and XPF

artículo científico publicado en 1998

Maxi-circles and mini-circles in kinetoplast DNA from trypanosoma cruzi

scientific article published on 01 April 1980

Meningococcal disease in The Netherlands, 1959-1981: the occurrence of serogroups and serotypes 2a and 2b of Neisseria meningitidis

artículo científico publicado en 1986

Microinjected photoreactivating enzymes from Anacystis and Saccharomyces monomerize dimers in chromatin of human cells

artículo científico publicado en 1985

Microinjection of Micrococcus luteus UV-endonuclease restores UV-induced unscheduled DNA synthesis in cells of 9 xeroderma pigmentosum complementation groups

artículo científico publicado en 1985

Microinjection of human cell extracts corrects xeroderma pigmentosum defect ⬇️

artículo científico publicado el 1 de enero de 1983

Molecular and cellular analysis of the DNA repair defect in a patient in xeroderma pigmentosum complementation group D who has the clinical features of xeroderma pigmentosum and Cockayne syndrome

artículo científico publicado en 1995

Molecular and functional analysis of theXPBC/ERCC-3promoter: transcription activity is dependent on the integrity of an Sp1-binding site ⬇️

artículo científico publicado el 25 de enero de 1992

Molecular basis of DNA repair mechanisms and syndromes

artículo científico publicado en 1998

Molecular characterization of the human excision repair gene ERCC-1: cDNA cloning and amino acid homology with the yeast DNA repair gene RAD10.

artículo científico publicado en 1986

Molecular cloning and biological characterization of the human excision repair gene ERCC-3

artículo científico publicado en 1990

Molecular cloning of a human DNA repair gene

artículo científico publicado en 1984

Molecular cloning of the human DNA excision repair gene ERCC-6

artículo científico publicado en 1990

Molecular mechanism of nucleotide excision repair.

artículo científico publicado en 1999

Mutation of the mouse Rad17 gene leads to embryonic lethality and reveals a role in DNA damage-dependent recombination

scientific journal article

Mutational analysis of the human nucleotide excision repair gene ERCC1

artículo científico publicado en 1996

Novel expression-linked copies of the genes for variant surface antigens in trypanosomes

scientific article published in Nature

Novel functional interactions between nucleotide excision DNA repair proteins influencing the enzymatic activities of TFIIH, XPG, and ERCC1-XPF

scientific journal article

Nucleocytoplasmic shuttling and mCRY-dependent inhibition of ubiquitylation of the mPER2 clock protein

artículo científico publicado en 2002

Phenotypic heterogeneity in nucleotide excision repair mutants of rodent complementation groups 1 and 4

scientific article published on 01 March 1997

Photic induction of mPer1 and mPer2 in cry-deficient mice lacking a biological clock

artículo científico publicado en 1999

Polyubiquitination of proliferating cell nuclear antigen by HLTF and SHPRH prevents genomic instability from stalled replication forks

artículo científico publicado en 2008

Premature aging in mice deficient in DNA repair and transcription

scientific journal article

RAD25 (SSL2), the yeast homolog of the human xeroderma pigmentosum group B DNA repair gene, is essential for viability ⬇️

artículo científico publicado el 1 de diciembre de 1992

RNA from the insect trypanosome Crithidia luciliae contains transcripts of the maxi-circle and not of the mini-circle component of kinetoplast DNA.

artículo científico publicado en 1978

Rec8p, a meiotic recombination and sister chromatid cohesion phosphoprotein of the Rad21p family conserved from fission yeast to humans

artículo científico publicado en 1999

Recombination and joining: different means to the same ends

artículo científico publicado en 1997

Reduced hematopoietic reserves in DNA interstrand crosslink repair-deficient Ercc1-/- mice

scientific journal article

Rescue of progeria in trichothiodystrophy by homozygous lethal Xpd alleles

artículo científico publicado en 2006

Retinal degeneration and ionizing radiation hypersensitivity in a mouse model for Cockayne syndrome

scientific journal article

Sequence conservation of the rad21 Schizosaccharomyces pombe DNA double-strand break repair gene in human and mouse

artículo científico publicado en 1996

Sequential assembly of the nucleotide excision repair factors in vivo

scientific journal article

Silencing of unpaired chromatin and histone H2A ubiquitination in mammalian meiosis

scientific journal article

Structural and functional conservation of two human homologs of the yeast DNA repair gene RAD6

artículo científico publicado en 1991

Structure and expression of the excision repair gene ERCC6, involved in the human disorder Cockayne's syndrome group B

artículo científico publicado en 1993

Structure and expression of the human XPBC/ERCC-3 gene involved in DNA repair disorders xeroderma pigmentosum and Cockayne's syndrome

artículo científico publicado en 1991

Structure of the nuclear pore complex in mammalian cells Two annular components ⬇️

artículo científico publicado el 1 de julio de 1974

Sublimiting concentration of TFIIH transcription/DNA repair factor causes TTD-A trichothiodystrophy disorder

artículo científico publicado en 2000

TFIIH with inactive XPD helicase functions in transcription initiation but is defective in DNA repair.

artículo científico publicado en 2000

Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice

artículo científico publicado en 2000

The ERCC2/DNA repair protein is associated with the class II BTF2/TFIIH transcription factor

artículo científico publicado en 1994

The HhH domain of the human DNA repair protein XPF forms stable homodimers

artículo científico publicado en 2008

The XPB and XPD DNA helicases are components of the p53-mediated apoptosis pathway

artículo científico publicado en 1996

The XPB subunit of repair/transcription factor TFIIH directly interacts with SUG1, a subunit of the 26S proteasome and putative transcription factor

artículo científico publicado en 1997

The cloned human DNA excision repair gene ERCC-1 fails to correct xeroderma pigmentosum complementation groups A through I

artículo científico publicado en 1989

The genes for variant antigens in trypanosomes

artículo científico publicado en 1980

The human RAD54 recombinational DNA repair protein is a double-stranded DNA-dependent ATPase

artículo científico publicado en 1998

The isolation of plasmids containing DNA complementary to messenger RNA for variant surface glycoproteins of Trypanosoma brucei

artículo científico publicado en 1980

The kinetoplast DNA of Trypanosoma equiperdum

scientific article published on 01 May 1980

The major transcripts of the kinetoplast DNA of Trypanosoma brucei are very small ribosomal RNAs.

artículo científico publicado en 1983

The progeroid phenotype of Ku80 deficiency is dominant over DNA-PKCS deficiency

artículo científico publicado en 2014

The rhp6+ gene of Schizosaccharomyces pombe: a structural and functional homolog of the RAD6 gene from the distantly related yeast Saccharomyces cerevisiae

artículo científico publicado en 1990

The structure of the XPF-ssDNA complex underscores the distinct roles of the XPF and ERCC1 helix- hairpin-helix domains in ss/ds DNA recognition

artículo científico publicado en 2012

The structure-specific endonuclease Ercc1-Xpf is required for targeted gene replacement in embryonic stem cells

artículo científico publicado en 2001

The structure-specific endonuclease Ercc1-Xpf is required to resolve DNA interstrand cross-link-induced double-strand breaks

scientific journal article

The ubiquitin-conjugating DNA repair enzyme HR6A is a maternal factor essential for early embryonic development in mice

artículo científico publicado en 2004

Transcription of kinetoplast DNA in Trypanosoma brucei bloodstream and culture forms ⬇️

artículo científico publicado el 1 de mayo de 1981

Transcription-coupled and global genome repair differentially influence UV-B-induced acute skin effects and systemic immunosuppression

scientific journal article

Transcription-coupled repair and premature ageing

artículo científico publicado en 2005

Transfection of the cloned human excision repair gene ERCC-1 to UV-sensitive CHO mutants only corrects the repair defect in complementation group-2 mutants

artículo científico publicado en 1988

Transient correction of excision repair defects in fibroblasts of 9 xeroderma pigmentosum complementation groups by microinjection of crude human cell extracts

scientific article published on 01 May 1986

Translocation of Cockayne syndrome group A protein to the nuclear matrix: possible relevance to transcription-coupled DNA repair

artículo científico publicado en 2002

Two Human Homologs of Rad23 Are Functionally Interchangeable in Complex Formation and Stimulation of XPC Repair Activity ⬇️

artículo científico publicado el 1 de diciembre de 1997

UV-sensitive syndrome protein UVSSA recruits USP7 to regulate transcription-coupled repair

artículo científico publicado en 2012

Ubiquitin ligase Rad18Sc localizes to the XY body and to other chromosomal regions that are unpaired and transcriptionally silenced during male meiotic prophase

scientific journal article

Variations in maxi-circle and mini-circle sequences in kinetoplast DNAs from different Trypanosoma brucei strains ⬇️

artículo científico publicado el 11 de diciembre de 1980

Versatile DNA damage detection by the global genome nucleotide excision repair protein XPC

artículo científico publicado en 2008

Workshop on DNA repair

artículo científico publicado en 1992

XAB2, a novel tetratricopeptide repeat protein involved in transcription-coupled DNA repair and transcription

artículo científico publicado en 2000

XPC and human homologs of RAD23: intracellular localization and relationship to other nucleotide excision repair complexes

artículo científico publicado en 1996

Xeroderma pigmentosum complementation group H falls into complementation group D

scientific article published on 01 September 1991

Xeroderma pigmentosum group A correcting protein from calf thymus

artículo científico publicado el 1 de septiembre de 1992

Xeroderma pigmentosum group C protein complex is the initiator of global genome nucleotide excision repair

artículo científico publicado en 1998

Xeroderma pigmentosum group F caused by a defect in a structure-specific DNA repair endonuclease

artículo científico publicado en 1996

p44 and p34 subunits of the BTF2/TFIIH transcription factor have homologies with SSL1, a yeast protein involved in DNA repair

artículo científico publicado en 1994

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