Lista de obras - Hans-Joachim Knölker - Dominio Público Uruguay

(η4-Benzylideneacetone)tricarbonyliron

4Alpha-bromo-5alpha-cholestan-3beta-ol and nor-5alpha-cholestan-3beta-ol derivatives-stereoselective synthesis and hormonal activity in Caenorhabditis elegans.

artículo científico publicado en 2009

A Novel Method for the Demetalation of Tricarbonyliron-Diene Complexes by a Photolytically Induced Ligand Exchange Reaction with Acetonitrile

scientific article published on 01 March 1999

A Novel Method for the Synthesis of Isocyanates Under Mild Conditions

scholarly article by Hans-Joachim Knölker et al published 1 December 1995 in Angewandte Chemie International Edition

A novel pyrrole synthesis

artículo científico publicado en 2004

A wax ester promotes collective host finding in the nematode Pristionchus pacificus.

artículo científico publicado en 2014

Analysis of amino-terminal variants of amyloid-β peptides by capillary isoelectric focusing immunoassay

artículo científico publicado en 2013

Analysis of bioactive oxysterols in newborn mouse brain by LC/MS.

artículo científico publicado en 2012

Anti-tuberculosis activity and structure-activity relationships of oxygenated tricyclic carbazole alkaloids and synthetic derivatives

artículo científico publicado en 2016

Astrocytes and microglia but not neurons preferentially generate N-terminally truncated Aβ peptides

artículo científico publicado en 2014

Brown Algae (Phaeophyceae) from the Coast of Madagascar: preliminary Bioactivity Studies and Isolation of Natural Products

artículo científico publicado en 2015

Chemical constituents isolated from Zygophyllum melongena Bunge growing in Mongolia

artículo científico publicado en 2016

Chemical constituents of the soft corals Sinularia vanderlandi and Sinularia gravis from the coast of Madagascar

artículo científico publicado en 2015

Chemistry and biology of carbazole alkaloids

artículo científico publicado en 2008

Concentrations of halogenated natural products versus PCB 153 in bivalves from the North and Baltic Seas

artículo científico publicado en 2014

Conversion of Olefins into Ketones by an Iron-Catalyzed Wacker-type Oxidation Using Oxygen as the Sole Oxidant

artículo científico publicado en 2017

Cross-talk between the calcium channel TRPV4 and reactive oxygen species interlocks adhesive and degradative functions of invadosomes

artículo científico publicado en 2021

DAF-12 regulates a connected network of genes to ensure robust developmental decisions.

artículo científico publicado en 2011

Determination of 4-nonylphenol in water samples using 4-(2,6-dimethylhept-3-yl)phenol as new internal standard

artículo científico publicado en 2010

Development and Technical Validation of an Immunoassay for the Detection of APP669-711 (Aβ-3-40) in Biological Samples

scientific article published on 08 September 2020

Discovery and widespread occurrence of polyhalogenated 1,1'-dimethyl-2,2'-bipyrroles (PDBPs) in marine biota ⬇️

artículo científico publicado el 18 de abril de 2013

Efficient construction of pyrano[3,2-a]carbazoles: application to a biomimetic total synthesis of cyclized monoterpenoid pyrano[3,2-a]carbazole alkaloids

artículo científico publicado en 2013

Efficient inhibition of the Alzheimer's disease beta-secretase by membrane targeting

artículo científico publicado en 2008

Efficient iron-mediated approach to pyrano[3,2-a]carbazole alkaloids--first total syntheses of O-methylmurrayamine A and 7-methoxymurrayacine, first asymmetric synthesis and assignment of the absolute configuration of (-)-trans-dihydroxygirinimbine

scientific article published on 31 January 2011

Enantioselective Total Synthesis and Assignment of the Absolute Configuration of the Furo[3,2- a]carbazole Alkaloid Furoclausine-B

scientific article published on 11 December 2018

Endocannabinoids in Caenorhabditis elegans are essential for the mobilization of cholesterol from internal reserves

artículo científico publicado en 2018

Evaluation of steroidal amines as lipid raft modulators and potential anti-influenza agents ⬇️

artículo científico publicado el 18 de julio de 2013

First enantioselective total synthesis of neocarazostatin B, determination of its absolute configuration and transformation into carquinostatin A

artículo científico publicado en 2006

First total syntheses of chrestifoline-B and (±)-chrestifoline-C, and improved synthetic routes to bismurrayafoline-A, bismurrayafolinol and chrestifoline-D

artículo científico publicado en 2014

First total synthesis of clausine L and pityriazole, a metabolite of the human pathogenic yeast Malassezia furfur

scientific article published on 22 May 2008

First total synthesis of the 7-oxygenated carbazole alkaloids clauszoline-K, 3-formyl-7-hydroxycarbazole, clausine M, clausine N and the anti-HIV active siamenol using a highly efficient palladium-catalyzed approach

artículo científico publicado en 2006

First total synthesis of the biologically active 2,7-dioxygenated tricyclic carbazole alkaloids 7-methoxy-O-methylmukonal, clausine H (clauszoline-C), clausine K (clauszoline-J) and clausine O.

artículo científico publicado en 2005

First total synthesis of the biscarbazole alkaloid oxydimurrayafoline ⬇️

artículo científico publicado el 12 de junio de 2012

First total synthesis of the neuronal cell protecting carbazole alkaloid carbazomadurin A by sequential transition metal-catalyzed reactions

artículo científico publicado en 2003

First total synthesis of the whole series of the antiostatins A and B.

artículo científico publicado en 2009

IR, Raman, and UV/Vis spectra of corannulene for use in possible interstellar identification

artículo científico publicado en 2008

In thematic volumes of The Alkaloids seminal developments in areas of exceptional interest are summarized.

artículo científico publicado en 2016

In vitro and in vivo effects of inhibitors on actin and myosin

artículo científico publicado en 2020

Inhibition of Myosin ATPase activity by halogenated pseudilins: a structure-activity study

artículo científico publicado en 2011

Inhibitory effect of oxygenated cholestan-3β-ol derivatives on the growth of Mycobacterium tuberculosis

artículo científico publicado en 2013

Iron catalysis in organic synthesis

artículo científico publicado en 2015

Iron-Catalyzed Oxidative C-C Cross-Coupling Reaction of Tertiary Anilines with Hydroxyarenes by Using Air as Sole Oxidant

artículo científico publicado en 2020

Iron-Catalyzed Oxidative C-C and N-N Coupling of Diarylamines and Synthesis of Spiroacridines

artículo científico publicado en 2016

Iron-Catalyzed Synthesis, Structure, and Photophysical Properties of Tetraarylnaphthidines

artículo científico publicado en 2020

Isolation and structure elucidation of natural products of three soft corals and a sponge from the coast of Madagascar

artículo científico publicado en 2017

Isolation and synthesis of biologically active carbazole alkaloids

artículo científico publicado en 2002

Lipidomimetic Compounds Act as HIV-1 Entry Inhibitors by Altering Viral Membrane Structure

article

Mechanism and Specificity of Pentachloropseudilin-mediated Inhibition of Myosin Motor Activity

artículo científico publicado en 2011

Membrane domain-disrupting effects of 4-substitued cholesterol derivatives

artículo científico publicado en 2008

Methylation of the sterol nucleus by STRM-1 regulates dauer larva formation in Caenorhabditis elegans.

artículo científico publicado en 2009

Myosin 1E localizes to actin polymerization sites in lamellipodia, affecting actin dynamics and adhesion formation

artículo científico publicado en 2013

Myosin 1b functions as an effector of EphB signaling to control cell repulsion

artículo científico publicado en 2015

Myosin 1b promotes axon formation by regulating actin wave propagation and growth cone dynamics

artículo científico publicado en 2018

Myosin-1 inhibition by PClP affects membrane shape, cortical actin distribution and lipid droplet dynamics in early Zebrafish embryos

artículo científico publicado en 2017

Myosin-II-mediated cell shape changes and cell intercalation contribute to primitive streak formation.

artículo científico publicado en 2015

Novel approach to biscarbazole alkaloids via Ullmann coupling--synthesis of murrastifoline-A and bismurrayafoline-A

artículo científico publicado en 2012

Nuclear hormone receptor regulation of microRNAs controls innate immune responses in C. elegans

artículo científico publicado en 2013

Occurrence, biogenesis, and synthesis of biologically active carbazole alkaloids

artículo científico

Organosilicon-mediated total synthesis of the triquinane sesquiterpenes (±)-β-isocomene and (±)-isocomene ⬇️

artículo científico publicado el 28 de julio de 2010

Palladium(II)-catalysed total synthesis of naturally occurring pyrano[3,2-a]carbazole and pyrano[2,3-b]carbazole alkaloids

artículo científico publicado en 2014

Palladium-catalyzed total synthesis of euchrestifoline using a one-pot Wacker oxidation and double aromatic C-H bond activation

artículo científico publicado en 2008

Pentabromopseudilin: a myosin V inhibitor suppresses TGF-β activity by recruiting the type II TGF-β receptor to lysosomal degradation

scientific article published on 01 December 2018

Pentachloropseudilin Impairs Angiogenesis by Disrupting the Actin Cytoskeleton, Integrin Trafficking and the Cell Cycle

scientific article published on 07 August 2019

Pentachloropseudilin inhibits transforming growth factor-β (TGF-β) activity by accelerating cell-surface type II TGF-β receptor turnover in target cells

artículo científico publicado en 2018

Pharmacological Inhibition of Amyloidogenic APP Processing and Knock-Down of APP in Primary Human Macrophages Impairs the Secretion of Cytokines

scientific article published on 03 September 2020

Phosphorylated glycosphingolipids essential for cholesterol mobilization in Caenorhabditis elegans

artículo científico publicado en 2017

Preface

scientific article published on 25 December 2013

Preface

artículo científico publicado en 2019

Preface

Pseudilins: halogenated, allosteric inhibitors of the non-mevalonate pathway enzyme IspD

artículo científico publicado en 2014

Quantitative Structure-Retention Relationships for Polycyclic Aromatic Hydrocarbons and their Oligoalkynyl-Substituted Derivatives.

artículo científico publicado en 2017

Red Algae (Rhodophyta) from the Coast of Madagascar: Preliminary Bioactivity Studies and Isolation of Natural Products

artículo científico publicado en 2015

Reductive Eliminations from Diarylpalladium(II) Complexes: A Combined Experimental and Computational Investigation

artículo científico publicado en 2017

Regio- and Stereospecific Synthesis of Cholesterol Derivatives and Their Hormonal Activity inCaenorhabditis elegans

Regioselective prenylation of bromocarbazoles by palladium(0)-catalysed cross coupling--synthesis of O-methylsiamenol, O-methylmicromeline and carquinostatin A

artículo científico publicado en 2014

Silver(I)-Catalyzed Route to Pyrroles: Synthesis of Halogenated Pseudilins as Allosteric Inhibitors for Myosin ATPase and X-ray Crystal Structures of the Protein-Inhibitor Complexes

Snapshot of the palladium(II)-catalyzed oxidative biaryl bond formation by X-ray analysis of the intermediate diaryl palladium(II) complex

scientific article published on 14 December 2011

Solid-Phase Synthesis and Characterization of N-Terminally Elongated Aβ-3-x -Peptides

artículo científico publicado en 2016

Spectroscopy of dibenzorubicene: experimental data for a search in interstellar spectra.

artículo científico publicado en 2011

Stereoselective synthesis and hormonal activity of novel dafachronic acids and naturally occurring steroids isolated from corals

artículo científico publicado en 2012

Stereoselective synthesis of the hormonally active (25S)-delta7-dafachronic acid, (25S)-Delta4-dafachronic acid, (25S)-dafachronic acid, and (25S)-cholestenoic acid

artículo científico publicado en 2008

Steroid hormones controlling the life cycle of the nematode Caenorhabditis elegans: stereoselective synthesis and biology

artículo científico publicado en 2009

Sterol-derived hormone(s) controls entry into diapause in Caenorhabditis elegans by consecutive activation of DAF-12 and DAF-16

artículo científico publicado en 2004

Structural design, solid-phase synthesis and activity of membrane-anchored β-secretase inhibitors on Aβ generation from wild-type and Swedish-mutant APP.

artículo científico publicado en 2010

Subcellular targeting strategies for drug design and delivery

artículo científico publicado en 2010

Synthesis and Activity against Mycobacterium tuberculosis of Olivacine and Oxygenated Derivatives

artículo científico publicado en 2018

Synthesis and Activity of Carbazole Derivatives Against Mycobacterium tuberculosis

artículo científico publicado en 2006

Synthesis and Crystal Structure of Dimorphic Dibenzo[cde,opq]rubicene

scientific article published on 24 September 2019

Synthesis and biological activity of (24E)- and (24Z)-26-hydroxydesmosterol

artículo científico publicado en 2013

Synthesis and biological activity of the (25R)-cholesten-26-oic acids--ligands for the hormonal receptor DAF-12 in Caenorhabditis elegans

artículo científico publicado en 2009

Synthesis of 1,1'- and 2,2'-Bicarbazole Alkaloids by Iron(III)-Catalyzed Oxidative Coupling of 2- and 1-Hydroxycarbazoles.

artículo científico publicado en 2017

Synthesis of Glycoborine, Glybomine A and B, the Phytoalexin Carbalexin A and the β-Adrenoreceptor Antagonists Carazolol and Carvedilol.

artículo científico publicado en 2016

Synthesis of Methylene-Bridged Biscarbazole Alkaloids by using an Ullmann-type Coupling: First Total Synthesis of Murrastifoline-C and Murrafoline-E

scientific article published on 20 January 2016

Synthesis of Stable Diarylpalladium(II) Complexes: Detailed Study of the Aryl-Aryl Bond-Forming Reductive Elimination

artículo científico publicado en 2016

Synthesis of Tetranuclear Palladium(II) Complexes and Their Catalytic Activity for Cross-Coupling Reactions

artículo científico publicado en 2017

Synthesis of prenyl- and geranyl-substituted carbazole alkaloids by DIBAL-H promoted reductive pyran ring opening of dialkylpyrano[3,2-a]carbazoles

artículo científico publicado en 2014

Synthesis of pyrrole and carbazole alkaloids

artículo científico publicado en 2012

The Pyrrolo[2,1-a]isoquinoline Alkaloids ⬇️

artículo científico publicado el 1 de enero de 2011

The mechanism of pentabromopseudilin inhibition of myosin motor activity

artículo científico publicado en 2009

The motor protein Myo1c regulates transforming growth factor-β-signaling and fibrosis in podocytes

scientific article published on 04 March 2019

The role of myosin 1c and myosin 1b in surfactant exocytosis

artículo científico publicado en 2016

Total syntheses of murrayamine E, I, and K

artículo científico publicado en 2015

Total synthesis of 7- and 8-oxygenated pyrano[3,2-a]carbazole and pyrano[2,3-a]carbazole alkaloids via boronic acid-catalyzed annulation of the pyran ring

artículo científico publicado en 2014

Total synthesis of biologically active alkaloids using transition metals

Total synthesis of pentabromo- and pentachloropseudilin, and synthetic analogues--allosteric inhibitors of myosin ATPase

artículo científico publicado en 2009

Total synthesis of the biscarbazole alkaloids murrafoline A-D by a domino sonogashira coupling/claisen rearrangement/electrocyclization reaction

artículo científico publicado en 2013

Total synthesis of the cyclic monoterpenoid pyrano[3,2-a]carbazole alkaloids derived from 2-hydroxy-6-methylcarbazole

article published in 2014

Transition metals in organic synthesis - Part 83#: Synthesis and pharmacological potential of carbazoles

Validation of soluble amyloid-β precursor protein assays as diagnostic CSF biomarkers for neurodegenerative diseases

artículo científico publicado en 2016

Lista de obras de Hans-Joachim Knölker

(η4-Benzylideneacetone)tricarbonyliron

4Alpha-bromo-5alpha-cholestan-3beta-ol and nor-5alpha-cholestan-3beta-ol derivatives-stereoselective synthesis and hormonal activity in Caenorhabditis elegans.

A Novel Method for the Demetalation of Tricarbonyliron-Diene Complexes by a Photolytically Induced Ligand Exchange Reaction with Acetonitrile

A Novel Method for the Synthesis of Isocyanates Under Mild Conditions

A novel pyrrole synthesis

A wax ester promotes collective host finding in the nematode Pristionchus pacificus.

Analysis of amino-terminal variants of amyloid-β peptides by capillary isoelectric focusing immunoassay

Analysis of bioactive oxysterols in newborn mouse brain by LC/MS.

Anti-tuberculosis activity and structure-activity relationships of oxygenated tricyclic carbazole alkaloids and synthetic derivatives

Astrocytes and microglia but not neurons preferentially generate N-terminally truncated Aβ peptides

Brown Algae (Phaeophyceae) from the Coast of Madagascar: preliminary Bioactivity Studies and Isolation of Natural Products

Chemical constituents isolated from Zygophyllum melongena Bunge growing in Mongolia

Chemical constituents of the soft corals Sinularia vanderlandi and Sinularia gravis from the coast of Madagascar

Chemistry and biology of carbazole alkaloids

Concentrations of halogenated natural products versus PCB 153 in bivalves from the North and Baltic Seas

Conversion of Olefins into Ketones by an Iron-Catalyzed Wacker-type Oxidation Using Oxygen as the Sole Oxidant

Cross-talk between the calcium channel TRPV4 and reactive oxygen species interlocks adhesive and degradative functions of invadosomes

DAF-12 regulates a connected network of genes to ensure robust developmental decisions.

Determination of 4-nonylphenol in water samples using 4-(2,6-dimethylhept-3-yl)phenol as new internal standard

Development and Technical Validation of an Immunoassay for the Detection of APP669-711 (Aβ-3-40) in Biological Samples

Discovery and widespread occurrence of polyhalogenated 1,1'-dimethyl-2,2'-bipyrroles (PDBPs) in marine biota ⬇️

Efficient construction of pyrano[3,2-a]carbazoles: application to a biomimetic total synthesis of cyclized monoterpenoid pyrano[3,2-a]carbazole alkaloids

Efficient inhibition of the Alzheimer's disease beta-secretase by membrane targeting

Efficient iron-mediated approach to pyrano[3,2-a]carbazole alkaloids--first total syntheses of O-methylmurrayamine A and 7-methoxymurrayacine, first asymmetric synthesis and assignment of the absolute configuration of (-)-trans-dihydroxygirinimbine

Enantioselective Total Synthesis and Assignment of the Absolute Configuration of the Furo[3,2- a]carbazole Alkaloid Furoclausine-B

Endocannabinoids in Caenorhabditis elegans are essential for the mobilization of cholesterol from internal reserves

Evaluation of steroidal amines as lipid raft modulators and potential anti-influenza agents ⬇️

First enantioselective total synthesis of neocarazostatin B, determination of its absolute configuration and transformation into carquinostatin A

First total syntheses of chrestifoline-B and (±)-chrestifoline-C, and improved synthetic routes to bismurrayafoline-A, bismurrayafolinol and chrestifoline-D

First total synthesis of clausine L and pityriazole, a metabolite of the human pathogenic yeast Malassezia furfur

First total synthesis of the 7-oxygenated carbazole alkaloids clauszoline-K, 3-formyl-7-hydroxycarbazole, clausine M, clausine N and the anti-HIV active siamenol using a highly efficient palladium-catalyzed approach

First total synthesis of the biologically active 2,7-dioxygenated tricyclic carbazole alkaloids 7-methoxy-O-methylmukonal, clausine H (clauszoline-C), clausine K (clauszoline-J) and clausine O.

First total synthesis of the biscarbazole alkaloid oxydimurrayafoline ⬇️

First total synthesis of the neuronal cell protecting carbazole alkaloid carbazomadurin A by sequential transition metal-catalyzed reactions

First total synthesis of the whole series of the antiostatins A and B.

IR, Raman, and UV/Vis spectra of corannulene for use in possible interstellar identification

In thematic volumes of The Alkaloids seminal developments in areas of exceptional interest are summarized.

In vitro and in vivo effects of inhibitors on actin and myosin

Inhibition of Myosin ATPase activity by halogenated pseudilins: a structure-activity study

Inhibitory effect of oxygenated cholestan-3β-ol derivatives on the growth of Mycobacterium tuberculosis

Iron catalysis in organic synthesis

Iron-Catalyzed Oxidative C-C Cross-Coupling Reaction of Tertiary Anilines with Hydroxyarenes by Using Air as Sole Oxidant

Iron-Catalyzed Oxidative C-C and N-N Coupling of Diarylamines and Synthesis of Spiroacridines

Iron-Catalyzed Synthesis, Structure, and Photophysical Properties of Tetraarylnaphthidines

Isolation and structure elucidation of natural products of three soft corals and a sponge from the coast of Madagascar

Isolation and synthesis of biologically active carbazole alkaloids

Lipidomimetic Compounds Act as HIV-1 Entry Inhibitors by Altering Viral Membrane Structure

Mechanism and Specificity of Pentachloropseudilin-mediated Inhibition of Myosin Motor Activity

Membrane domain-disrupting effects of 4-substitued cholesterol derivatives

Methylation of the sterol nucleus by STRM-1 regulates dauer larva formation in Caenorhabditis elegans.

Myosin 1E localizes to actin polymerization sites in lamellipodia, affecting actin dynamics and adhesion formation

Myosin 1b functions as an effector of EphB signaling to control cell repulsion

Myosin 1b promotes axon formation by regulating actin wave propagation and growth cone dynamics

Myosin-1 inhibition by PClP affects membrane shape, cortical actin distribution and lipid droplet dynamics in early Zebrafish embryos

Myosin-II-mediated cell shape changes and cell intercalation contribute to primitive streak formation.

Novel approach to biscarbazole alkaloids via Ullmann coupling--synthesis of murrastifoline-A and bismurrayafoline-A

Nuclear hormone receptor regulation of microRNAs controls innate immune responses in C. elegans

Occurrence, biogenesis, and synthesis of biologically active carbazole alkaloids

Organosilicon-mediated total synthesis of the triquinane sesquiterpenes (±)-β-isocomene and (±)-isocomene ⬇️

Palladium(II)-catalysed total synthesis of naturally occurring pyrano[3,2-a]carbazole and pyrano[2,3-b]carbazole alkaloids

Palladium-catalyzed total synthesis of euchrestifoline using a one-pot Wacker oxidation and double aromatic C-H bond activation

Pentabromopseudilin: a myosin V inhibitor suppresses TGF-β activity by recruiting the type II TGF-β receptor to lysosomal degradation

Pentachloropseudilin Impairs Angiogenesis by Disrupting the Actin Cytoskeleton, Integrin Trafficking and the Cell Cycle

Pentachloropseudilin inhibits transforming growth factor-β (TGF-β) activity by accelerating cell-surface type II TGF-β receptor turnover in target cells

Pharmacological Inhibition of Amyloidogenic APP Processing and Knock-Down of APP in Primary Human Macrophages Impairs the Secretion of Cytokines

Phosphorylated glycosphingolipids essential for cholesterol mobilization in Caenorhabditis elegans

Preface

Preface

Preface

Preface

Preface

Pseudilins: halogenated, allosteric inhibitors of the non-mevalonate pathway enzyme IspD

Quantitative Structure-Retention Relationships for Polycyclic Aromatic Hydrocarbons and their Oligoalkynyl-Substituted Derivatives.

Red Algae (Rhodophyta) from the Coast of Madagascar: Preliminary Bioactivity Studies and Isolation of Natural Products

Reductive Eliminations from Diarylpalladium(II) Complexes: A Combined Experimental and Computational Investigation

Regio- and Stereospecific Synthesis of Cholesterol Derivatives and Their Hormonal Activity inCaenorhabditis elegans

Regioselective prenylation of bromocarbazoles by palladium(0)-catalysed cross coupling--synthesis of O-methylsiamenol, O-methylmicromeline and carquinostatin A

Silver(I)-Catalyzed Route to Pyrroles: Synthesis of Halogenated Pseudilins as Allosteric Inhibitors for Myosin ATPase and X-ray Crystal Structures of the Protein-Inhibitor Complexes

Snapshot of the palladium(II)-catalyzed oxidative biaryl bond formation by X-ray analysis of the intermediate diaryl palladium(II) complex