Lista de obras - Gert Fricker - Dominio Público Uruguay

A Kinome-Wide Selective Radiolabeled TrkB/C Inhibitor for in Vitro and in Vivo Neuroimaging: Synthesis, Preclinical Evaluation, and First-in-Human

artículo científico

A fluorescence-based in vitro assay for drug interactions with breast cancer resistance protein (BCRP, ABCG2).

artículo científico publicado en 2009

A simple method to quickly and simultaneously purify and enrich intact rat brain microcapillaries and endothelial and glial cells for ex vivo studies and cell culture

artículo científico publicado en 2013

ABC transporters at the blood-brain barrier

artículo científico publicado en 2016

Alkamides from Echinacea angustifolia Interact with P-glycoprotein of primary brain capillary endothelial cells isolated from porcine brain blood vessels

artículo científico publicado en 2013

Alkylglycerol opening of the blood-brain barrier to small and large fluorescence markers in normal and C6 glioma-bearing rats and isolated rat brain capillaries

artículo científico publicado en 2003

Amorphous solid dispersion enhances permeation of poorly soluble ABT-102: true supersaturation vs. apparent solubility enhancement

article by Kerstin J Frank et al published 20 August 2012 in International Journal of Pharmaceutics

Application of simulated intestinal fluid on the phospholipid vesicle-based drug permeation assay.

artículo científico publicado en 2011

Archaeal lipids in oral delivery of therapeutic peptides.

artículo científico publicado en 2017

Aryl hydrocarbon receptor ligands increase ABC transporter activity and protein expression in killifish (Fundulus heteroclitus) renal proximal tubules

artículo científico publicado en 2019

BCRP at the Blood−Brain Barrier: Genomic Regulation by 17β-Estradiol ⬇️

artículo científico publicado el 9 de septiembre de 2010

Biological effects of acrylamide after daily ingestion of various foods in comparison to water: A study in rats ⬇️

artículo científico publicado el 11 de octubre de 2010

Biopharmaceutical classification of poorly soluble drugs with respect to "enabling formulations".

artículo científico

Blood Trimethylamine-N-Oxide Originates from Microbiota Mediated Breakdown of Phosphatidylcholine and Absorption from Small Intestine

artículo científico publicado en 2017

Brain delivery of camptothecin by means of solid lipid nanoparticles: formulation design, in vitro and in vivo studies

artículo científico publicado en 2012

By-passing of P-glycoprotein using immunoliposomes

artículo científico publicado en 2002

Cellular uptake of PLGA nanoparticles targeted with anti-amyloid and anti-transferrin receptor antibodies for Alzheimer's disease treatment.

artículo científico publicado en 2016

Characterization of cytochrome P450 protein expression along the entire length of the intestine of male and female rats

artículo científico publicado en 2008

Characterization of efflux transport proteins of the human choroid plexus papilloma cell line HIBCPP, a functional in vitro model of the blood-cerebrospinal fluid barrier

artículo científico publicado en 2015

Characterization of immortalized choroid plexus epithelial cell lines for studies of transport processes across the blood-cerebrospinal fluid barrier

artículo científico publicado en 2010

Choroid plexus epithelial monolayers--a cell culture model from porcine brain

artículo científico publicado en 2006

Cloning and characterization of a novel apolipoprotein A-I binding protein, AI-BP, secreted by cells of the kidney proximal tubules in response to HDL or ApoA-I

artículo científico publicado en 2002

Closing the gaps: a full scan of the intestinal expression of p-glycoprotein, breast cancer resistance protein, and multidrug resistance-associated protein 2 in male and female rats

artículo científico publicado en 2008

Comparative Assessment of Complex Stabilities of Radiocopper Chelating Agents by a Combination of Complex Challenge and in vivo Experiments.

artículo científico publicado en 2015

Compound profiling for ABCC2 (MRP2) using a fluorescent microplate assay system

artículo científico publicado en 2007

Compound profiling for P-glycoprotein at the blood-brain barrier using a microplate screening system

artículo científico publicado en 2003

Confocal imaging of organic anion transport in intact rat choroid plexus

artículo científico publicado en 2002

Correction to: Current research into brain barriers and the delivery of therapeutics for neurological diseases: a report on CNS barrier congress London, UK, 2017.

artículo científico publicado en 2018

Current State of Radiolabeled Heterobivalent Peptidic Ligands in Tumor Imaging and Therapy

artículo científico publicado en 2020

Current research into brain barriers and the delivery of therapeutics for neurological diseases: a report on CNS barrier congress London, UK, 2017.

artículo científico publicado en 2017

Current status in the therapy of liver diseases

artículo científico

Cytotoxicity and inhibition of P-glycoprotein by selected medicinal plants from Thailand

artículo científico publicado en 2014

Cytotoxicity and p-glycoprotein modulating effects of quinolones and indoloquinazolines from the Chinese herb Evodia rutaecarpa.

artículo científico publicado en 2007

David S. Miller: Scientist, Mentor, Friend-a tribute and thank you

scientific article published on 14 September 2020

Delivery of Copper-chelating Trientine (TETA) to the central nervous system by surface modified liposomes

artículo científico publicado en 2016

Delivery of nanoparticles to the brain detected by fluorescence microscopy

artículo científico publicado en 2008

Design and synthesis of a fluorinated quinazoline-based type-II Trk inhibitor as a scaffold for PET radiotracer development

artículo científico publicado en 2017

Design of novel artemisinin-like derivatives with cytotoxic and anti-angiogenic properties

artículo científico publicado en 2010

Design, Synthesis, In Vitro, and Initial In Vivo Evaluation of Heterobivalent Peptidic Ligands Targeting Both NPY(Y₁)- and GRP-Receptors-An Improvement for Breast Cancer Imaging?

scholarly article by Alicia Vall-Sagarra et al published 4 July 2018 in Pharmaceuticals

Development and characterization of novel highly-loaded itraconazole poly(butyl cyanoacrylate) polymeric nanoparticles

artículo científico publicado en 2017

Development and lyophilization of itraconazole loaded poly(butylcyanoacrylate) nanospheres as a drug delivery system

artículo científico publicado en 2015

Development and validation of a LC-MS/MS method for assessment of an anti-inflammatory indolinone derivative by in vitro blood-brain barrier models

artículo científico publicado en 2014

Development of a New Method to Assess Nanocrystal Dissolution Based on Light Scattering ⬇️

artículo científico publicado el 12 de junio de 2012

Development of a fluorescence-based assay for drug interactions with human Multidrug Resistance Related Protein (MRP2; ABCC2) in MDCKII-MRP2 membrane vesicles

artículo científico publicado en 2010

Drug interactions with natural products at the blood brain barrier

artículo científico publicado en 2008

Dual asymmetric centrifugation as a novel method to prepare highly concentrated dispersions of PEG-b-PCL polymersomes as drug carriers

scientific article published on 22 March 2020

Dual ligand immunoliposomes for drug delivery to the brain.

artículo científico publicado en 2015

Dynamic regulation of P-glycoprotein in human brain capillaries.

artículo científico publicado en 2013

Effect of phospholipid-based formulations of Boswellia serrata extract on the solubility, permeability, and absorption of the individual boswellic acid constituents present

artículo científico publicado en 2012

Effect of the non-ionic surfactant Poloxamer 188 on passive permeability of poorly soluble drugs across Caco-2 cell monolayers

artículo científico publicado en 2011

Electrospray Synthesis of Poly(lactide-co-glycolide) Nanoparticles Encapsulating Peptides to Enhance Proliferation of Antigen-Specific CD8+ T Cells

artículo científico publicado en 2017

Engaging neuroscience to advance translational research in brain barrier biology.

artículo científico publicado en 2011

Enhanced absorption of boswellic acids by a lecithin delivery form (Phytosome(®)) of Boswellia extract

artículo científico publicado en 2012

Enhancement of oral bioavailability of E804 by self-nanoemulsifying drug delivery system (SNEDDS) in rats

artículo científico publicado en 2013

Establishment of optimized MDCK cell lines for reliable efflux transport studies

artículo científico publicado en 2014

Exploring the fate of liposomes in the intestine by dynamic in vitro lipolysis

Extension of the mechanistic tissue distribution model of Rodgers & Rowland by systematic incorporation of lysosomal trapping: impact on Kpu and volume of distribution predictions in the rat

artículo científico publicado en 2020

Fluo-cAMP is transported by multidrug resistance-associated protein isoform 4 in rat choroid plexus.

artículo científico publicado en 2010

Fluorescein-methotrexate transport in dogfish shark (Squalus acanthias) choroid plexus

artículo científico publicado en 2006

Fluorescein-methotrexate transport in rat choroid plexus analyzed using confocal microscopy

artículo científico publicado en 2004

Formation of nano/micro-dispersions with improved dissolution properties upon dispersion of ritonavir melt extrudate in aqueous media

artículo científico publicado en 2010

Formulation optimization of itraconazole loaded PEGylated liposomes for parenteral administration by using design of experiments

artículo científico publicado en 2013

From blood to brain and vice versa: transport processes in choroid plexus can be studied in vitro.

artículo científico publicado en 2007

Genomic Knockout of Endogenous Canine P-Glycoprotein in Wild-Type, Human P-Glycoprotein and Human BCRP Transfected MDCKII Cell Lines by Zinc Finger Nucleases

artículo científico publicado en 2014

Glutaric aciduria type I and methylmalonic aciduria: simulation of cerebral import and export of accumulating neurotoxic dicarboxylic acids in in vitro models of the blood-brain barrier and the choroid plexus

artículo científico

Identification of [18F]TRACK, a Fluorine-18-Labeled Tropomyosin Receptor Kinase (Trk) Inhibitor for PET Imaging

artículo científico publicado en 2017

Impact of FaSSIF on the solubility and dissolution-/permeation rate of a poorly water-soluble compound

artículo científico publicado en 2012

Impact of Zn2+ on ABC Transporter Function in Intact Isolated Rat Brain Microvessels, Human Brain Capillary Endothelial Cells, and in Rat in Vivo

artículo científico publicado en 2018

Improved Oral Bioavailability of Human Growth Hormone by a Combination of Liposomes Containing Bio-Enhancers and Tetraether Lipids and Omeprazole

artículo científico publicado en 2014

In Vitro and In Situ Absorption and Metabolism of Sesquiterpenes from Petasites hybridus Extracts

artículo científico publicado en 2018

In Vitro and In Situ Characterization of Triterpene Glycosides From Cimicifuga racemosa Extract

artículo científico publicado en 2017

In situ formation of nanoparticles upon dispersion of melt extrudate formulations in aqueous medium assessed by asymmetrical flow field-flow fractionation

artículo científico publicado en 2010

In vitro and in vivo evaluations of the performance of an indirubin derivative, formulated in four different self-emulsifying drug delivery systems

In vitro cytotoxicity and P-glycoprotein modulating effects of geranylated furocoumarins from Tetradium daniellii.

artículo científico publicado en 2007

In vitro evaluation of liposomes containing bio-enhancers for the oral delivery of macromolecules.

artículo científico publicado en 2010

In vitro metabolism, permeation, and brain availability of six major boswellic acids from Boswellia serrata gum resins

artículo científico publicado en 2012

In vitro models to evaluate the permeability of poorly soluble drug entities: challenges and perspectives

artículo científico

In-vitro permeability of poorly water soluble drugs in the phospholipid vesicle-based permeation assay: the influence of nonionic surfactants

artículo científico publicado en 2011

In-vitro permeability screening of melt extrudate formulations containing poorly water-soluble drug compounds using the phospholipid vesicle-based barrier.

artículo científico publicado en 2010

Inhibition of P-glycoprotein at the blood-brain barrier by phytochemicals derived from traditional Chinese medicine.

artículo científico publicado en 2010

Inhibition of P-glycoprotein by two artemisinin derivatives.

artículo científico publicado en 2012

Intracerebral accumulation of glutaric and 3-hydroxyglutaric acids secondary to limited flux across the blood-brain barrier constitute a biochemical risk factor for neurodegeneration in glutaryl-CoA dehydrogenase deficiency

artículo científico publicado en 2006

Lack of biliary lipid excretion in the little skate, Raja erinacea, indicates the absence of functional Mdr2, Abcg5, and Abcg8 transporters

artículo científico publicado en 2003

Lipid Profiles of Five Essential Phospholipid Preparations for the Treatment of Nonalcoholic Fatty Liver Disease: A Comparative Study

scientific article published on 07 April 2020

Liposomal conjugates for drug delivery to the central nervous system

artículo científico publicado en 2015

Localization microscopy (SPDM) reveals clustered formations of P-glycoprotein in a human blood-brain barrier model

artículo científico publicado en 2012

Matrix-loaded biodegradable gelatin nanoparticles as new approach to improve drug loading and delivery

artículo científico publicado en 2010

Modification with organometallic compounds improves crossing of the blood-brain barrier of [Leu5]-enkephalin derivatives in an in vitro model system

artículo científico publicado en 2009

Modulation of drug transporters at the blood-brain barrier

artículo científico publicado en 2004

Modulation of p-glycoprotein transport function at the blood-brain barrier

artículo científico publicado en 2005

Modulation of transendothelial permeability and expression of ATP-binding cassette transporters in cultured brain capillary endothelial cells by astrocytic factors and cell-culture conditions

artículo científico publicado en 2003

NOD-scid IL2R γnull mice engrafted with human peripheral blood mononuclear cells as a model to test therapeutics targeting human signaling pathways

artículo científico publicado en 2013

Nanotoxicity of poly(n-butylcyano-acrylate) nanoparticles at the blood-brain barrier, in human whole blood and in vivo

artículo científico publicado en 2014

Nitensidine A, a guanidine alkaloid from Pterogyne nitens, is a novel substrate for human ABC transporter ABCB1.

artículo científico publicado en 2013

Oral bioavailability of ketoprofen in suspension and solution formulations in rats: the influence of poloxamer 188

artículo científico publicado en 2012

Oral delivery of vancomycin by tetraether lipid liposomes.

artículo científico publicado en 2017

Oral peptide delivery by tetraether lipid liposomes ⬇️

artículo científico publicado el 2 de junio de 2011

Permeability of porcine blood brain barrier to somatostatin analogues

artículo científico publicado en 2002

Permeation of Boswellia extract in the Caco-2 model and possible interactions of its constituents KBA and AKBA with OATP1B3 and MRP2.

artículo científico publicado en 2008

Phospholipids and lipid-based formulations in oral drug delivery

artículo científico publicado en 2010

Physicochemical and biopharmaceutical characterization of novel Matrix-Liposomes

scientific article published on 06 June 2020

Physicochemical characterization and in vitro permeation of an indirubin derivative

artículo científico publicado en 2013

Potent and selective inhibitors of breast cancer resistance protein (ABCG2) derived from the p-glycoprotein (ABCB1) modulator tariquidar

artículo científico publicado en 2009

Pregnane X receptor (PXR) regulates P-glycoprotein at the blood-brain barrier: functional similarities between pig and human PXR.

artículo científico publicado en 2009

Pregnane X receptor up-regulation of P-glycoprotein expression and transport function at the blood-brain barrier

artículo científico publicado en 2004

Quantitation of lysosomal trapping of basic lipophilic compounds using in vitro assays and in silico predictions based on the determination of the full pH profile of the endo-/lysosomal system in rat hepatocytes

artículo científico publicado en 2018

Radioligands for Tropomyosin Receptor Kinase (Trk) Positron Emission Tomography Imaging

artículo científico publicado en 2019

Radionuclides in drug development

artículo científico publicado en 2014

Rapid assessment of p-glycoprotein-drug interactions at the blood-brain barrier

artículo científico publicado en 2006

Rapid modulation of P-glycoprotein-mediated transport at the blood-brain barrier by tumor necrosis factor-alpha and lipopolysaccharide

artículo científico publicado en 2005

Rapid regulation of P-glycoprotein at the blood-brain barrier by endothelin-1.

artículo científico publicado en 2004

Regional absorption of fexofenadine in rat intestine ⬇️

artículo científico publicado el 30 de septiembre de 2010

Relevance of multidrug resistance proteins for intestinal drug absorption in vitro and in vivo

artículo científico publicado en 2002

Retention of structural and functional polarity in cultured skate hepatocytes undergoing in vitro morphogenesis

artículo científico publicado en 2006

Short- and long-term influences of heavy metals on anionic drug efflux from renal proximal tubule.

artículo científico publicado en 2002

Shuttle-cargo fusion molecules of transport peptides and the hD2/3 receptor antagonist fallypride: a feasible approach to preserve ligand-receptor binding?

St. John's Wort constituents modulate P-glycoprotein transport activity at the blood-brain barrier

artículo científico publicado en 2010

Stability of liposomes containing bio-enhancers and tetraether lipids in simulated gastro-intestinal fluids ⬇️

artículo científico publicado el 9 de diciembre de 2010

Sugar Codes Conjugated Alginate: An Innovative Platform to Make a Strategic Breakthrough in Simultaneous Prophylaxis of GERD and Helicobacter pylori Infection

scientific article published on 17 June 2020

Surveillance of siRNA integrity by FRET imaging

artículo científico publicado en 2007

Synthesis, in vitro and in vivo evaluation of 18F-fluoronorimatinib as radiotracer for Imatinib-sensitive gastrointestinal stromal tumors

artículo científico publicado en 2017

Texas Red transport across rat and dogfish shark (Squalus acanthias) choroid plexus

artículo científico publicado en 2008

The ABC of the Blood-Brain Barrier - Regulation of Drug Efflux Pumps ⬇️

artículo científico publicado el 1 de enero de 2011

The Bile Acid-Phospholipid Conjugate Ursodeoxycholyl-Lysophosphatidylethanolamide (UDCA-LPE) Disintegrates the Lipid Backbone of Raft Plasma Membrane Domains by the Removal of the Membrane Phospholipase A2

artículo científico publicado en 2019

The Influence of Liquid Intake on the Performance of an Amorphous Solid Dispersion in Rats

artículo científico publicado en 2020

The amorphous solid dispersion of the poorly soluble ABT-102 forms nano/microparticulate structures in aqueous medium: impact on solubility.

artículo científico publicado en 2012

The application of P-gp inhibiting phospholipids as novel oral bioavailability enhancers - An in vitro and in vivo comparison.

artículo científico publicado en 2016

Transport of a fluorescent cAMP analog in teleost proximal tubules

artículo científico publicado en 2007

Transport of paclitaxel (Taxol) across the blood-brain barrier in vitro and in vivo

artículo científico publicado en 2002

Uptake of apolipoprotein E fragment coupled liposomes by cultured brain microvessel endothelial cells and intact brain capillaries

artículo científico publicado en 2009

What is the mechanism behind increased permeation rate of a poorly soluble drug from aqueous dispersions of an amorphous solid dispersion?

artículo científico publicado en 2014

Xenobiotic efflux pumps in isolated fish brain capillaries

artículo científico publicado en 2002

Zinc chloride rapidly stimulates efflux transporters in renal proximal tubules of killifish (Fundulus heteroclitus).

artículo científico publicado en 2017

Lista de obras de Gert Fricker

A Kinome-Wide Selective Radiolabeled TrkB/C Inhibitor for in Vitro and in Vivo Neuroimaging: Synthesis, Preclinical Evaluation, and First-in-Human

A fluorescence-based in vitro assay for drug interactions with breast cancer resistance protein (BCRP, ABCG2).

A simple method to quickly and simultaneously purify and enrich intact rat brain microcapillaries and endothelial and glial cells for ex vivo studies and cell culture

ABC transporters at the blood-brain barrier

Alkamides from Echinacea angustifolia Interact with P-glycoprotein of primary brain capillary endothelial cells isolated from porcine brain blood vessels

Alkylglycerol opening of the blood-brain barrier to small and large fluorescence markers in normal and C6 glioma-bearing rats and isolated rat brain capillaries

Amorphous solid dispersion enhances permeation of poorly soluble ABT-102: true supersaturation vs. apparent solubility enhancement

Application of simulated intestinal fluid on the phospholipid vesicle-based drug permeation assay.

Archaeal lipids in oral delivery of therapeutic peptides.

Aryl hydrocarbon receptor ligands increase ABC transporter activity and protein expression in killifish (Fundulus heteroclitus) renal proximal tubules

BCRP at the Blood−Brain Barrier: Genomic Regulation by 17β-Estradiol ⬇️

Biological effects of acrylamide after daily ingestion of various foods in comparison to water: A study in rats ⬇️

Biopharmaceutical classification of poorly soluble drugs with respect to "enabling formulations".

Blood Trimethylamine-N-Oxide Originates from Microbiota Mediated Breakdown of Phosphatidylcholine and Absorption from Small Intestine

Brain delivery of camptothecin by means of solid lipid nanoparticles: formulation design, in vitro and in vivo studies

By-passing of P-glycoprotein using immunoliposomes

Cellular uptake of PLGA nanoparticles targeted with anti-amyloid and anti-transferrin receptor antibodies for Alzheimer's disease treatment.

Characterization of cytochrome P450 protein expression along the entire length of the intestine of male and female rats

Characterization of efflux transport proteins of the human choroid plexus papilloma cell line HIBCPP, a functional in vitro model of the blood-cerebrospinal fluid barrier

Characterization of immortalized choroid plexus epithelial cell lines for studies of transport processes across the blood-cerebrospinal fluid barrier

Choroid plexus epithelial monolayers--a cell culture model from porcine brain

Cloning and characterization of a novel apolipoprotein A-I binding protein, AI-BP, secreted by cells of the kidney proximal tubules in response to HDL or ApoA-I

Closing the gaps: a full scan of the intestinal expression of p-glycoprotein, breast cancer resistance protein, and multidrug resistance-associated protein 2 in male and female rats

Comparative Assessment of Complex Stabilities of Radiocopper Chelating Agents by a Combination of Complex Challenge and in vivo Experiments.

Compound profiling for ABCC2 (MRP2) using a fluorescent microplate assay system

Compound profiling for P-glycoprotein at the blood-brain barrier using a microplate screening system

Confocal imaging of organic anion transport in intact rat choroid plexus

Correction to: Current research into brain barriers and the delivery of therapeutics for neurological diseases: a report on CNS barrier congress London, UK, 2017.

Current State of Radiolabeled Heterobivalent Peptidic Ligands in Tumor Imaging and Therapy

Current research into brain barriers and the delivery of therapeutics for neurological diseases: a report on CNS barrier congress London, UK, 2017.

Current status in the therapy of liver diseases

Cytotoxicity and inhibition of P-glycoprotein by selected medicinal plants from Thailand

Cytotoxicity and p-glycoprotein modulating effects of quinolones and indoloquinazolines from the Chinese herb Evodia rutaecarpa.

David S. Miller: Scientist, Mentor, Friend-a tribute and thank you

Delivery of Copper-chelating Trientine (TETA) to the central nervous system by surface modified liposomes

Delivery of nanoparticles to the brain detected by fluorescence microscopy

Design and synthesis of a fluorinated quinazoline-based type-II Trk inhibitor as a scaffold for PET radiotracer development

Design of novel artemisinin-like derivatives with cytotoxic and anti-angiogenic properties

Design, Synthesis, In Vitro, and Initial In Vivo Evaluation of Heterobivalent Peptidic Ligands Targeting Both NPY(Y₁)- and GRP-Receptors-An Improvement for Breast Cancer Imaging?

Development and characterization of novel highly-loaded itraconazole poly(butyl cyanoacrylate) polymeric nanoparticles

Development and lyophilization of itraconazole loaded poly(butylcyanoacrylate) nanospheres as a drug delivery system

Development and validation of a LC-MS/MS method for assessment of an anti-inflammatory indolinone derivative by in vitro blood-brain barrier models

Development of a New Method to Assess Nanocrystal Dissolution Based on Light Scattering ⬇️

Development of a fluorescence-based assay for drug interactions with human Multidrug Resistance Related Protein (MRP2; ABCC2) in MDCKII-MRP2 membrane vesicles

Drug interactions with natural products at the blood brain barrier

Dual asymmetric centrifugation as a novel method to prepare highly concentrated dispersions of PEG-b-PCL polymersomes as drug carriers

Dual ligand immunoliposomes for drug delivery to the brain.

Dynamic regulation of P-glycoprotein in human brain capillaries.

Effect of phospholipid-based formulations of Boswellia serrata extract on the solubility, permeability, and absorption of the individual boswellic acid constituents present

Effect of the non-ionic surfactant Poloxamer 188 on passive permeability of poorly soluble drugs across Caco-2 cell monolayers

Electrospray Synthesis of Poly(lactide-co-glycolide) Nanoparticles Encapsulating Peptides to Enhance Proliferation of Antigen-Specific CD8+ T Cells

Engaging neuroscience to advance translational research in brain barrier biology.

Enhanced absorption of boswellic acids by a lecithin delivery form (Phytosome(®)) of Boswellia extract

Enhancement of oral bioavailability of E804 by self-nanoemulsifying drug delivery system (SNEDDS) in rats

Establishment of optimized MDCK cell lines for reliable efflux transport studies

Exploring the fate of liposomes in the intestine by dynamic in vitro lipolysis

Extension of the mechanistic tissue distribution model of Rodgers & Rowland by systematic incorporation of lysosomal trapping: impact on Kpu and volume of distribution predictions in the rat

Fluo-cAMP is transported by multidrug resistance-associated protein isoform 4 in rat choroid plexus.

Fluorescein-methotrexate transport in dogfish shark (Squalus acanthias) choroid plexus

Fluorescein-methotrexate transport in rat choroid plexus analyzed using confocal microscopy

Formation of nano/micro-dispersions with improved dissolution properties upon dispersion of ritonavir melt extrudate in aqueous media

Formulation optimization of itraconazole loaded PEGylated liposomes for parenteral administration by using design of experiments

From blood to brain and vice versa: transport processes in choroid plexus can be studied in vitro.

Genomic Knockout of Endogenous Canine P-Glycoprotein in Wild-Type, Human P-Glycoprotein and Human BCRP Transfected MDCKII Cell Lines by Zinc Finger Nucleases

Glutaric aciduria type I and methylmalonic aciduria: simulation of cerebral import and export of accumulating neurotoxic dicarboxylic acids in in vitro models of the blood-brain barrier and the choroid plexus

Identification of [18F]TRACK, a Fluorine-18-Labeled Tropomyosin Receptor Kinase (Trk) Inhibitor for PET Imaging

Impact of FaSSIF on the solubility and dissolution-/permeation rate of a poorly water-soluble compound

Impact of Zn2+ on ABC Transporter Function in Intact Isolated Rat Brain Microvessels, Human Brain Capillary Endothelial Cells, and in Rat in Vivo

Improved Oral Bioavailability of Human Growth Hormone by a Combination of Liposomes Containing Bio-Enhancers and Tetraether Lipids and Omeprazole

In Vitro and In Situ Absorption and Metabolism of Sesquiterpenes from Petasites hybridus Extracts

In Vitro and In Situ Characterization of Triterpene Glycosides From Cimicifuga racemosa Extract

In situ formation of nanoparticles upon dispersion of melt extrudate formulations in aqueous medium assessed by asymmetrical flow field-flow fractionation

In vitro and in vivo evaluations of the performance of an indirubin derivative, formulated in four different self-emulsifying drug delivery systems

In vitro cytotoxicity and P-glycoprotein modulating effects of geranylated furocoumarins from Tetradium daniellii.

In vitro evaluation of liposomes containing bio-enhancers for the oral delivery of macromolecules.

In vitro metabolism, permeation, and brain availability of six major boswellic acids from Boswellia serrata gum resins

In vitro models to evaluate the permeability of poorly soluble drug entities: challenges and perspectives

In-vitro permeability of poorly water soluble drugs in the phospholipid vesicle-based permeation assay: the influence of nonionic surfactants

In-vitro permeability screening of melt extrudate formulations containing poorly water-soluble drug compounds using the phospholipid vesicle-based barrier.